Esomeprazole magnesium

This page contains recent news articles, when available, and an overview of Esomeprazole magnesium but does not offer medical advice. You should contact your physician with regard to any health issues or concerns.


Overview:

Esomeprazole magnesium
(when available)

Pharmacology and use:
Omeprazole is a compound that inhibits gastric acid secretion and is indicated in the treatment of gastroesophageal reflux disease (GERD), the healing of erosive esophagitis, and H. pylori eradication to reduce the risk of duodenal ulcer recurrence. Omeprazole belongs to a new class of antisecretory compounds, the substituted benzimidazoles, that do not exhibit anticholinergic or H2 histamine antagonistic properties, but that suppress gastric acid secretion by specific inhibition of the H+/K+ ATPase enzyme system at the secretory surface of the gastric parietal cell. Because this enzyme system is regarded as the acid (proton) pump within the gastric mucosa, Omeprazole has been characterized as a gastric acid-pump inhibitor, in that it blocks the final step of acid production. This effect is dose-related and leads to inhibition of both basal and stimulated acid secretion irrespective of the stimulus. For the treatment of gastroesophageal reflux disease

Mechanism Of Action:
Omeprazole is a proton pump inhibitor that suppresses gastric acid secretion by specific inhibition of the H+/K+-ATPase in the gastric parietal cell. By acting specifically on the proton pump, Omeprazole blocks the final step in acid production, thus reducing gastric acidity.

News Articles on Omeprazole

Ranbaxy sure of monetising Flomax, Lipitor, Nexium  -  ‎Dec 14, 2009‎
...in the drug ---esomeprazole magnesium --- to AstraZeneca from May 2009 and gains from selling some Nexium from May 2010 as per other settlements. ... Daily News & Analysis

Outsourcing steroid for Indian pharma firms  -  ‎Dec 20, 2009‎
...of active pharmaceutical ingredient supply of the heartburn drug, Nexium (esomeprazole magnesium), to AstraZeneca, which has started since this May. ... Rediff

'Tis the season for heartburn-free holidays  -  ‎Dec 11, 2009‎
One such PPI, called NEXIUM (esomeprazole magnesium), is prescribed to treat the symptoms of acid reflux disease, which typically include persistent ... Anahuac Progress

Patients Taking VIMOVO(TM) Showed a Decrease in Incidence of NSAID-Associated ...  -  ‎Oct 19, 2009‎
The data demonstrated that patients at risk for developing NSAID-associated gastric ulcers taking VIMOVO(TM) (naproxen/esomeprazole magnesium, ... Reuters

POZEN Reports Third Quarter 2009 Results  -  ‎Oct 28, 2009‎
...of $14.3 million resulting from a $10 million milestone payment for the New Drug Application (NDA) filing for VIMOVO (naproxen/esomeprazole magnesium), ... Reuters

AstraZeneca sues Lupin for 'infringing on' drug patent  -  ‎Nov 10, 2009‎
...patent coverage by attempting to manufacture and market anti-ulcer drug Nexium (esomeprazole magnesium), one of the top five blockbuster drugs globally. ... Financial Express

AstraZeneca And Pozen Reveal Pivotal Data From Two POZEN Clinical Trials ...  -  ‎Oct 19, 2009‎
The data demonstrated that patients at risk for developing NSAID-associated gastric ulcers taking VIMOVO (naproxen/esomeprazole magnesium, formerly known as ... RTT News

Patients taking VIMOVO showed improved UGI tolerability assessments as ...  -  ‎Oct 29, 2009‎
...(naproxen/esomeprazole magnesium), formerly known as PN 400, and enteric-coated (EC) naproxen alone in patients at risk for NSAID-associated ulcers. ... The FINANCIAL

AstraZeneca sues Lupin to protect patent rights of anti-ulcer drug, Nexium  -  ‎Nov 9, 2009‎
...to market the generic version of 20 and 40 mg esomeprazole magnesium delayed-release capsules, marketed by AstraZeneca under the brand name – Nexium. ... pharmabiz.com

Results of Phase I Study Show Novel, Investigational PA65020 Compound ...  -  ‎Oct 27, 2009‎
...the proposed trade name for the proprietary fixed dose combination of naproxen with the proton pump inhibitor esomeprazole magnesium in a single tablet ... Reuters

POZEN Reports Third Quarter 2009 Results  -  ‎Oct 29, 2009‎
...$14.3 million resulting from a $10 million milestone payment for the New Drug Application (NDA) filing for VIMOVO(TM) (naproxen/esomeprazole magnesium), ... The FINANCIAL

POZEN To Present at the Credit Suisse Healthcare Conference  -  ‎Oct 30, 2009‎
...the proposed trade name for the proprietary fixed dose combination of naproxen with the proton pump inhibitor esomeprazole magnesium in a single tablet ... Reuters

PicksThatMove: www.PicksThatMove.com: "Picks that move" Alerts, October 19 ...  -  ‎Oct 19, 2009‎
The data demonstrated that patients at risk for developing NSAID-associated gastric ulcers taking VIMOVO(TM) (naproxen/esomeprazole magnesium, ... Trading Markets (press release)

Ranbaxy settles patent issue with AstraZeneca  -  Apr 16, 2008
During the 180-day period following the date, Ranbaxy Pharma will be the only company to distribute Esomeprazole magnesium product in the US market. ... सिफी - सिफी

… Tentative Approval to Manufacture and Market Esomeprazole Magnesium...  -  Feb 7, 2008
...announced today that RLL has received tentative approval from the US Food and Drug Administration for Esomeprazole Magnesium Delayed-Release Capsules, ... Free with registration - PR Newswire - AccessMyLibrary.com

AstraZeneca: Esomeprazole magnesium cuts chest pain.  -  Nov 18, 2005
SAN FRANCISCO (MarketWatch) -- AstraZeneca Plc noted Friday that new clinical trial data shows the addition of the proton pump inhibitor esomeprazole ... Free with registration - America's Intelligence Wire - AccessMyLibrary.com

Article: Nexium (esomeprazole magnesium, AstraZeneca).(New & …  -  Apr 1, 2008
Nexium (esomeprazole magnesium, AstraZeneca).(New & Approved) ... find Pediatric News articles. The Food and Drug Administration approved the proton pump ... Pay-Per-View - Pediatric News - HighBeam Research

Press Release: FDA Approves NEXIUM for the Treatment of Zollinger- …  -  Oct 12, 2006
NEXIUM(R) (esomeprazole magnesium) was well tolerated throughout the trial. About ZES. ZES affects fewer than three out of every million Americans,(1) but ... Pay-Per-View - PR Newswire - HighBeam Research

… Announces NEXIUM(R)(esomeprazole magnesium) Savings Program for …  -  Nov 6, 2007
WILMINGTON, Del., Nov. 6 /PRNewswire-FirstCall/ -- AstraZeneca today announced the enhancements to the Purple Plus(TM) Program for patients with ... $4.95 - PR Newswire - ECNext

AstraZeneca submits sNDA for NEXIUM (esomeprazole magnesium)  -  Dec 21, 2008
AstraZeneca has announced the submission of a supplemental New Drug Application (sNDA) to the US Food and Drug Administration (FDA) for NEXIUM(R) ... News-Medical.net

… Announces NEXIUM(R)(esomeprazole magnesium) Savings Program for …  -  Nov 6, 2007
AstraZeneca Announces NEXIUM(R)(esomeprazole magnesium) Savings Program for Purple Plus(TM) Members. from PR Newswire. Highbeam Research – FREE Trial. Pay-Per-View - PR Newswire - HighBeam Research

Press Release: New Esomeprazole Magnesium Data in Non-cardiac …  -  Nov 18, 2005
New Esomeprazole Magnesium Data in Non-cardiac Chest Pain. from PR Newswire. Highbeam Research – FREE Trial. Pay-Per-View - PR Newswire - HighBeam Research

Nexium[R] (esomeprazole magnesium): AstraZeneca.(New Indication)  -  Feb 1, 2005
In addition to its original indication to treat frequent persistent heartburn and other symptoms associated with acid reflux disease, Nexium is now ... $4.95 - Clinician Reviews - ECNext

FDA Okays Esomeprazole (Nexium) for Pediatric GERD  -  Feb 28, 2008
28 -- The FDA today approved esomeprazole magnesium (Nexium) for short-term ... The FDA cautioned that the safety and efficacy of esomeprazole magnesium has ... MedPage Today

Press Release: Study Investigates NEXIUM(R) Benefits Patients With …  -  May 22, 2006
Article: AstraZeneca Announces NEXIUM(R)(esomeprazole magnesium) ... PR Newswire; November 6, 2007 ; 700+ words ... ... reflux disease (GERD) who are ... Pay-Per-View - PR Newswire - HighBeam Research

… Tentative Approval to Manufacture and Market Esomeprazole Magnesium...  -  Feb 7, 2008
Ranbaxy Receives Tentative Approval to Manufacture and Market Esomeprazole Magnesium DR Capsules. from PR Newswire. Highbeam Research – FREE Trial. Pay-Per-View - PR Newswire - HighBeam Research

FDA Concludes There is No Increased Risk of Cardiac Events for...  -  Dec 10, 2007
About NEXIUM(R) (esomeprazole magnesium). NEXIUM, launched in the US in 2001, is approved for the treatment of heartburn and other symptoms associated with ... Free with registration - PR Newswire - AccessMyLibrary.com

Article: Heartburn ads treat the pain of drug firms. - Chicago...  -  Mar 9, 2005
Oral Suspension 40 mg/1680 mg, Nexium(R) (esomeprazole magnesium) delayed-release capsules 40 mg and Prevacid(R) (lansoprazole) delayed ... while being ... Pay-Per-View - Chicago Tribune - HighBeam Research

Nexium - Esomeprazole magnesium trihydrate - Medical Drug  -  Jul 1, 2008
This is an ulcer caused by a bacterium called helicobacter pylori. Nexium and the antibiotics work together to eradicate the bacteria and allow the ulcer to ... Virtual Medical Centre - The Virtual Medical Centre

Press Release: Ranbaxy and AstraZeneca Reach Agreement in …  -  Apr 15, 2008
Two of these agreements concern Esomeprazole magnesium capsules. ... Article: New Esomeprazole Magnesium Data in Non-cardiac ... PR Newswire; November 18, ... Pay-Per-View - PR Newswire - HighBeam Research

Press Release: FDA Concludes There is No Increased Risk of Cardiac …  -  Dec 10, 2007
Article: Esomeprazole Magnesium Capsules ... Internal Medicine Alert; March 29, ... Article: Nexium (esomeprazole magnesium, AstraZeneca).(New & ... ... Pay-Per-View - PR Newswire - HighBeam Research

BARRX Medical, Inc. Initiates Landmark Study Comparing Two Treatment …  -  Mar 20, 2006
AstraZeneca (NYSE: AZN), makers of NEXIUM(R) (esomeprazole magnesium), ... All patients will receive esomeprazole magnesium (NEXIUM) as therapy for acid ... Free with registration - Business Wire - AccessMyLibrary.com

FDA Approvals: Nexium IV, Zofran, Xibrom  -  Apr 7, 2005
Esomeprazole magnesium oral therapy (Nexium delayed-release capsules, made by AstraZeneca) is indicated for the treatment of symptomatic GERD, ... Medscape

Article: Claim based on deceptive drug ads is preempted, Third...  -  Nov 1, 2007
Food and Drug Administration (FDA) has approved a new indication ... prescription proton pump inhibitor NEXIUM(R) (esomeprazole magnesium . ... Pay-Per-View - Trial - HighBeam Research

Loislaw Federal District Court Opinions - DR. REDDY'S LABORATORIES, …  -  Aug 28, 2008
Defendants, also drug manufacturers, market NEXIUM® esomeprazole magnesium 20mg and 40mg capsules. To that end, AstraZeneca owns a New Drug Application ... Pay-Per-View - Loislaw Federal District Court Opinions - Loislaw

New Study Shows Erosive Esophagitis Healing Linked To Gastric Acid …  -  May 23, 2006
About NEXIUM(R) (esomeprazole magnesium) delayed-release capsules NEXIUM is approved for treating frequent, persistent heartburn and other symptoms ... Medical News Today - Medical News Today (press release)

FDA Approves NEXIUM For The Treatment Of Zollinger-Ellison Syndrome  -  Oct 13, 2006
NEXIUM(R) (esomeprazole magnesium) was well tolerated throughout the trial. ZES affects fewer than three out of every million Americans,(1) but it is ... Medical News Today - Medical News Today (press release)

FDA Approves New Formulation For NEXIUM  -  Oct 25, 2006
About NEXIUM(R) (esomeprazole magnesium) Delayed-Release Capsules and For Delayed-Release Oral Suspension. NEXIUM is approved for treating frequent, ... Medical News Today - Medical News Today (press release)

Press Release: Obesity epidemic leading to increase in Upper GI …  -  Nov 15, 2007
Findings Demonstrates NEXIUM Maintained Normal Acid Production In ... that the proton pump inhibitor (PPI) NEXIUM(R) (esomeprazole magnesium) maintained . ... Pay-Per-View - M2 Presswire - HighBeam Research

Prilosec has enough going for it to jump-start antacids.  -  Oct 10, 2005
Nexium (esomeprazole magnesium), AstraZeneca PLC's prescription "purple pill" for acid reflux, is advertised aggressively and has many heartburn patients ... $9.94 - Chain Drug Review - Alacra Store

Article: BG gushes as Brazil looks a blockbuster ; MARKET ROUND-UP - ...  -  Apr 15, 2008
Article: AstraZeneca Announces NEXIUM(R)(esomeprazole magnesium) ... PR Newswire; November 6, 2007 ; 700+ words ... ... reflux disease (GERD) who are ... Pay-Per-View - Evening Standard - London - HighBeam Research

Press Release: NEXIUM(R) Shown to Reduce Gastric Ulcers in At-Risk …  -  Mar 22, 2006
PR Newswire; October 12, 2006 ; 700+ words ... ... prescription proton pump inhibitor NEXIUM(R) (esomeprazole magnesium ... Ellison Syndrome (ZES). ... Pay-Per-View - PR Newswire - HighBeam Research

NEXIUM® Savings Program for Purple Plusâ„¢ Members  -  Nov 15, 2007
NEXIUM® (esomeprazole magnesium) patients can enroll by: 1) Visiting www.PurplePill.com, 2) Calling 1-888-PurplePill, or 3) Activating the Purple Plus™ ... EndoNurse

Press Release: FDA Approves Use of NEXIUM(R) in Children Ages 12 to …  -  May 1, 2006
Article: Esomeprazole Magnesium Capsules ... Internal Medicine Alert; March 29, ... Article: Nexium (esomeprazole magnesium, AstraZeneca).(New & ... ... Pay-Per-View - PR Newswire - HighBeam Research

Press Release: AstraZeneca Submits sNDA for NEXIUM(R) for the Short- …  -  Dec 19, 2008
The formulation contains esomeprazole magnesium, the same active ingredient used in ... Article: AstraZeneca Announces NEXIUM(R)(esomeprazole magnesium) . ... Pay-Per-View - PR Newswire - HighBeam Research

Adverse Drug Reaction; Effects of esomeprazole in NSAID-induced …  -  Apr 19, 2005
Koch and colleagues published their study in Digestive Diseases and Sciences (Effects of esomeprazole magnesium on nonsteroidal anti-inflammatory drug ... Pay-Per-View - Science Letter - Factiva, from Dow Jones

FDA Approves NEXIUM for the Treatment of Zollinger-Ellison Syndrome.  -  Oct 12, 2006
NEXIUM(R) (esomeprazole magnesium) was well tolerated throughout the trial. ZES affects fewer than three out of every million Americans,(1) but it is ... Free with registration - PR Newswire - AccessMyLibrary.com

AstraZeneca Submits sNDA for NEXIUM(R) for the Short-Term Treatment …  -  Dec 19, 2008
The formulation contains esomeprazole magnesium, the same active ingredient used in NEXIUM Delayed-Release Capsules. The sNDA submission for NEXIUM in ... International Business Times

Press Release: Studies Show Body Mass Index Has No Effect on …  -  Oct 16, 2007
NEXIUM(R) (esomeprazole magnesium) Proven Effective at Standard Doses Regardless of Body Mass Index -. PHILADELPHIA, Oct. 16 /PRNewswire-FirstCall/ -- The ... Pay-Per-View - PR Newswire - HighBeam Research

Adverse Drug Reaction; Effects of esomeprazole in NSAID-induced …  -  Apr 18, 2005
Koch and colleagues published their study in Digestive Diseases and Sciences (Effects of esomeprazole magnesium on nonsteroidal anti-inflammatory drug ... Pay-Per-View - Pain & Central Nervous System Week - Factiva, from Dow Jones

NEXIUM(R) Maintains Healing Of Erosive Esophagitis Better Than …  -  Jul 26, 2006
About NEXIUM(R) (esomeprazole magnesium) Delayed-release Capsules NEXIUM is approved for treating frequent, persistent heartburn and other symptoms ... Medical News Today - Medical News Today (press release)

Adverse Drug Reaction; Effects of esomeprazole in NSAID-induced …  -  Apr 22, 2005
Koch and colleagues published their study in Digestive Diseases and Sciences (Effects of esomeprazole magnesium on nonsteroidal anti-inflammatory drug ... Pay-Per-View - Drug Week - Factiva, from Dow Jones

FDA Approves NEXIUM for Treatment of Zollinger-Ellison Syndrome  -  Oct 19, 2006
NEXIUM® (esomeprazole magnesium) was well tolerated throughout the trial. ZES affects fewer than three out of every million Americans, 1 but it is difficult ... EndoNurse

Nexium, Niox Mino.(New & Approved)(Drug overview) | Article from …  -  Apr 15, 2008
Nexium (esomeprazole magnesium, AstraZeneca) The Food and Drug ... (esomeprazole magnesium, AstraZeneca). The Food and Drug Administration approved the ... Pay-Per-View - Family Practice News - HighBeam Research

Article: Expert offers tips to avoid PPI failure in children with...  -  Feb 1, 2007
Article: Nexium (esomeprazole magnesium, AstraZeneca).(New & Approved) Pediatric News; April 1, 2008 ; 700+ words ...The Food and Drug Administration ... Pay-Per-View - Pediatric News - HighBeam Research

POZEN Reports Third Quarter 2006 Results.  -  Oct 31, 2006
...fixed dose combinations of the proton pump inhibitor esomeprazole magnesium, with the non-steroidal anti-inflammatory drug naproxen in a single tablet. ... $4.95 - Business Wire - ECNext

Press Release: FDA Approves Nexium for Use in Children Ages 1-11 …  -  Feb 28, 2008
The U.S. Food and Drug Administration approved Nexium (esomeprazole magnesium) for short-term use in children ages 1-11 years for the treatment of ... Pay-Per-View - M2 Presswire - HighBeam Research

Press Release: FDA Approves New Formulation for NEXIUM. - PR …  -  Oct 24, 2006
About NEXIUM(R) (esomeprazole magnesium) Delayed-Release Capsules and For Delayed-Release Oral Suspension. NEXIUM is approved for treating frequent, ... Pay-Per-View - PR Newswire - HighBeam Research

Suit seeks to block copy of Nexium  -  Nov 22, 2005
In its suit, the London-based drug maker accused Ranbaxy of "willful infringement" of its patents on esomeprazole magnesium. The drug is protected by six ... New York Times

On the Move: Metro, STM, Air France-KLM  -  Nov 22, 2005
The company has launched a patent infringement lawsuit against Ranbaxy for willful infringement of its patents protecting Nexium (esomeprazole magnesium). ... BusinessWeek

Atlanta health, diet and fitness news | ajc.com  -  Feb 28, 2008
The drug Nexium (esomeprazole magnesium) has been approved for short-term treatment of children ages one to 11 years with gastroesophageal reflux disease ... Atlanta Journal Constitution

On the Move: Capitalia, Endesa, BMW  -  Mar 9, 2006
...s patents protecting NEXIUM (esomeprazole magnesium). KUDELSKI was up CHF0.85 to CHF36.60. The company's Nagravision digital TV system has been selected by ... BusinessWeek

Ranbaxy gets tentative FDA okay for generic Nexium  -  Feb 7, 2008
Ranbaxy has first-to-file status on the drug, which is also known as esomeprazole magnesium, potentially giving it 180 days of marketing exclusivity when ... Reuters India

Pozen Announces August 2, 2007, Webcast.  -  Aug 2, 2007
...and with AstraZeneca for proprietary fixed dose combinations of naproxen with the proton pump inhibitor esomeprazole magnesium in a single tablet for ... Free with registration - Business Wire - AccessMyLibrary.com

Mkts: Bulls remain relentless @ 13:17 hrs  -  Apr 15, 2008
Two of these agreements concern Esomeprazole magnesium capsules. The third agreement pertains to Omeprazole 40mg tablets, and the fourth agreement pertains ... सिफी - सिफी

Dr Reddy's follows Teva on Nexium  -  Jun 6, 2008
...and Ranbaxy have also entered into a manufacturing contract for supply raw material for making esomeprazole magnesium to AstraZeneca from 2009 onwards. सिफी - सिफी

Wiley-Blackwell Press Room  -  Mar 27, 2006
...to be published in the April 2006 edition of the American Journal of Gastroenterology, indicate that esomeprazole magnesium can reduce the incidence of ... WIREs Nanomedicine and Nanobiotechnology

Perrigo to Launch Generic Prilosec OTC  -  Dec 19, 2007
...is no evidence of an increased risk of heart problems with Prilosec (omeprazole) or AstraZeneca's other heartburn drug, Nexium (esomeprazole magnesium). ... FDA news - FDA news (subscription)

Now, Ranbaxy seeks peace with Takeda  -  Jun 22, 2008
During the 180-day period following the date, Ranbaxy will distribute the only generic Esomeprazole magnesium product in the US market. ... Business Standard

AstraZeneca stock falls on threat to its best-selling drug | Article...  -  Feb 8, 2008
Ranbaxy has first-to-file status on the drug, which is also known as esomeprazole magnesium, potentially giving it six months of marketing exclusivity when ... Pay-Per-View - International Herald Tribune - HighBeam Research

Astrazaneca's Nexium threatened  -  Oct 19, 2005
In a statement on its website the UK-based firm said it had received a notice from Ranbaxy about the submission of an ANDA for Esomeprazole magnesium ... Financial Express

Court: FDA Approval Preempts State False Advertising Laws  -  Aug 24, 2007
...action suit in which a group of consumers sued AstraZeneca for engaging in deceptive conduct in its advertising of Nexium (esomeprazole magnesium). ... FDA news - FDA news (subscription)

NPS Appoints Dr. Bo Joelsson as Head of Clinical Research  -  May 13, 2008
...of several major gastrointestinal products, including Tagamet(R) (cimetidine), Prilosec(R) (omeprazole), and Nexium(R) (esomeprazole magnesium). ... Bloomberg

ì?˜ë£Œê³„ ì •ë¡  메디í?¬ë‰´ìФ  -  Apr 17, 2008
AZ는 란박시가 넥시움(esomeprazole magnesium)� 대한 복제품 제조를 위해 FDA� ... �로� 란박시는 2009년 5월부터 esomeprazole magnesium, 활성 성분 제조계약� ... 메디�뉴스

Esomeprazole for GI symptoms  -  Jun 7, 2005
Nottingham, UK - Two AstraZeneca-funded studies have found that esomeprazole magnesium (Nexium) cuts gastrointestinal (GI) symptoms in patients on chronic ... Medscape

Court: FDA Approval Preempts State False Advertising Laws  -  Aug 30, 2007
...action suit in which a group of consumers sued AstraZeneca for engaging in deceptive conduct in its advertising of Nexium (esomeprazole magnesium). ... FDA news - FDA news (subscription)

Santarus Announces DDW Clinical Abstract Regarding Nighttime Acid …  -  May 22, 2006
Nexium(R) (esomeprazole magnesium) delayed-release capsules 40 mg and Prevacid(R) (lansoprazole) delayed-release capsules 30 mg on an empty stomach at ... Free with registration - Business Wire - AccessMyLibrary.com

POZEN/AstraZeneca Announce Start of the PN 400 Phase III Program  -  Sep 7, 2007
...of the proton pump inhibitor (PPI), esomeprazole magnesium, with the non-steroidal anti-inflammatory drug (NSAID) naproxen, in a single tablet. ... carolinanewswire.com

AstraZeneca Proposes Mandatory FDA Review of All Pharmaceutical …  -  Nov 1, 2005
Reflecting those principles, television advertisements launched earlier this year for CRESTOR(R) (rosuvastatin) and NEXIUM(R) (esomeprazole magnesium) are ... $4.95 - PR Newswire - ECNext

POZEN Plans to Submit Response to Approvable Letter For Treximaâ„¢  -  Oct 5, 2007
...and with AstraZeneca for a proprietary fixed dose combination of naproxen with the proton pump inhibitor esomeprazole magnesium in a single tablet for ... carolinanewswire.com

PPIs May Be Cost-Effective in Some Patients Taking Prophylactic...  -  Aug 13, 2008
OTC PPIs (eg, omeprazole magnesium) vs higher-cost prescription PPIs (eg, esomeprazole magnesium, rabeprazole sodium, and pantoprazole sodium). ... Medscape

AstraZeneca Beats Back Legal Challenge by Pharmacies  -  Feb 28, 2008
...switched market demand from the prescription version of Prilosec (omeprazole magnesium) to an OTC version and Nexium (esomeprazole magnesium). ... FDA news - FDA news (subscription)

Pozen Expects to Submit Revised Response to Trexima(TM) (Sumatriptan …  -  Dec 13, 2006
...and with AstraZeneca for proprietary fixed dose combinations of the proton pump inhibitor esomeprazole magnesium with naproxen in a single tablet for ... Genetic Engineering News - Genetic Engineering News (press release)

POZEN Announces Positive Top Line Results for Its PN 400 Phase 3 …  -  Dec 3, 2008
...and with AstraZeneca for proprietary fixed dose combinations of naproxen with the proton pump inhibitor esomeprazole magnesium in a single tablet for ... carolinanewswire.com

AstraZeneca Commences Patent Infringement Litigation Against IVAX.  -  Mar 8, 2006
Ltd. and its US subsidiary, Teva Pharmaceuticals USA, for willful infringement of AstraZeneca's patents protecting NEXIUM(R) (esomeprazole magnesium). ... Free with registration - PR Newswire - AccessMyLibrary.com

POZEN and AstraZeneca Announce Global Collaboration to Co-Develop …  -  Aug 2, 2006
...fixed dose combinations of the proton pump inhibitor (PPI) esomeprazole magnesium, with the non-steroidal anti-inflammatory drug (NSAID) naproxen, ... Free with registration - Business Wire - AccessMyLibrary.com

Study compares stomach acid control of three proton pump inhibitors...  -  May 16, 2005
CHICAGO, IL, May 16th, 2005 бV Data from a clinical trial comparing stomach acid control of three proton pump inhibitors (PPIs), esomeprazole magnesium ... PsychCentral.com

POZEN Informed of FDA Internal Review of Gastric Ulcers as a Primary ...  -  Oct 17, 2008
...in adults, and with AstraZeneca for proprietary fixed dose combinations of naproxen with the proton pump inhibitor esomeprazole magnesium in a single ... Genetic Engineering News - Genetic Engineering News (press release)

FDA Reviewing Prilosec and Nexium, Finds No Increased Heart Risk  -  Aug 13, 2007
The FDA began a review of the products after results from a Prilosec (omeprazole) study and an analysis from an ongoing Nexium (esomeprazole magnesium) ... FDA news - FDA news (subscription)

Pozen Revises 2006 Guidance Upon Receipt of $40 M from AstraZeneca  -  Sep 21, 2006
...of fixed-dose single-tablet combinations of the proton pump inhibitor esomeprazole magnesium with the nonsteroidal anti-inflammatory drug naproxen. ... Genetic Engineering News - Genetic Engineering News (press release)

FDA Approves New Formulation for NEXIUM.  -  Oct 24, 2006
...for its prescription proton pump inhibitor NEXIUM (R) (esomeprazole magnesium) has been approved by the US Food and Drug Administration (FDA). ... Free with registration - PR Newswire - AccessMyLibrary.com

McKesson Sued for Alleged Drug Price Manipulation  -  May 23, 2008
...heartburn drug Nexium (esomeprazole magnesium) and diazepam, sold by Roche under the brand name Valium, as examples of allegedly overpriced drugs. ... FDA news - FDA news (subscription)

Pozen Announces Trexima(TM) (Sumatriptan Succinate and Naproxen …  -  Nov 1, 2007
...and with AstraZeneca for the proprietary fixed dose combination of the proton pump inhibitor esomeprazole magnesium with naproxen in a single tablet for ... Free with registration - Business Wire - AccessMyLibrary.com

POZEN Announces Receipt of Million in Milestone Payments From …  -  Apr 28, 2008
...and with AstraZeneca for proprietary fixed dose combinations of naproxen with the proton pump inhibitor esomeprazole magnesium in a single tablet for ... RedOrbit

POZEN Names Gilda M. Thomas as Senior Vice President and General …  -  Jan 10, 2007
...and with AstraZeneca for proprietary fixed dose combinations of the proton pump inhibitor esomeprazole magnesium with naproxen in a single tablet for ... Free with registration - Business Wire - AccessMyLibrary.com

POZEN Announces Settlement Agreement in Shareholder Lawsuit  -  Jul 10, 2007
...and with AstraZeneca for proprietary fixed dose combinations of naproxen with the proton pump inhibitor esomeprazole magnesium in a single tablet for ... carolinanewswire.com

POZEN Announces Positive Outcome for PA 325 Proof of Concept Study.  -  Mar 6, 2007
...and with AstraZeneca for proprietary fixed dose combinations of naproxen with the proton pump inhibitor esomeprazole magnesium in a single tablet for ... Free with registration - Business Wire - AccessMyLibrary.com

POZEN To Present at the 2007 UBS Global Generic and Specialty …  -  Apr 30, 2007
...and with AstraZeneca for proprietary fixed dose combinations of naproxen with the proton pump inhibitor esomeprazole magnesium in a single tablet for ... RedOrbit

14 News, The Tri-State's News and Weather Leader-Nexium Reduces …  -  Mar 22, 2006
The research was funded by the drug company AstraZeneca, which markets Nexium, known generically as esomeprazole magnesium. ... WFIE-TV

FDA Approves Use of NEXIUM(R) in Children Ages 12 to 17 For Short- …  -  May 1, 2006
...(esomeprazole magnesium) delayed release capsules, in children ages 12 to 17 for the short-term treatment of gastroesophageal reflux disease (GERD). ... Free with registration - PR Newswire - AccessMyLibrary.com

POZEN Announces October 29, 2008 Webcast of Third Quarter 2008 …  -  Oct 29, 2008
...and with AstraZeneca for proprietary fixed dose combinations of naproxen with the proton pump inhibitor esomeprazole magnesium in a single tablet for ... International Business Times

Studies Show Body Mass Index Has No Effect on Resolution and Healing ...  -  Oct 16, 2007
In the first study, data from two randomized, double-blind trials comparing NEXIUM(R) (esomeprazole magnesium) 20 mg or 40 mg once daily with placebo were ... Free with registration - PR Newswire - AccessMyLibrary.com

Trade Alert for Pozen, Inc.  -  Mar 23, 2007
...fixed dose combinations of the proton pump inhibitor (PPI) esomeprazole magnesium, with the non-steroidal anti-inflammatory drug (NSAID) naproxen, ... Free with registration - M2 Presswire - AccessMyLibrary.com

POZEN Announces May 2, 2007 Webcast of First Quarter 2007 Results  -  May 2, 2007
...and with AstraZeneca for proprietary fixed dose combinations of naproxen with the proton pump inhibitor esomeprazole magnesium in a single tablet for ... Genetic Engineering News - Genetic Engineering News (press release)

POZEN Submits Full Response to FDA Approvable Letter For Trexima(TM …  -  Nov 9, 2006
...and with AstraZeneca for proprietary fixed dose combinations of the proton pump inhibitor esomeprazole magnesium with naproxen in a single tablet for ... Free with registration - Business Wire - AccessMyLibrary.com

Study investigates Nexium benefits patients with Zollinger-Ellison …  -  May 22, 2006
A new clinical study shows that the proton pump inhibitor (PPI) Nexium (esomeprazole magnesium) maintained normal gastric (stomach) acid levels in patients ... Pay-Per-View - Company Reports - Factiva, from Dow Jones

NEXIUM(R) Shown To Reduce Gastric Ulcers In At-Risk Patients Using …  -  Mar 23, 2006
...indicate that NEXIUM(R) (esomeprazole magnesium) can reduce the incidence of gastric (stomach) ulcers in patients at risk of developing gastric ulcers ... Medical News Today - Medical News Today (press release)

Treatments and drugs  -  Jul 26, 2008
...medications include lansoprazole (Prevacid), omeprazole (Prilosec), pantaprazole (Protonix), rabeprazole (Aciphex), and esomeprazole magnesium (Nexium). ... MayoClinic.com

Treatment reduces gastric ulcers in at-risk patients using long-term ...  -  Mar 30, 2006
...to be published in the April 2006 edition of the American Journal of Gastroenterology, indicate that esomeprazole magnesium can reduce the incidence of ... News-Medical.net

NEXIUM® can reduce upper GI symptoms in patients using NSAIDS, …  -  May 15, 2005
Results from two clinical trials, published in the American Journal of Gastroenterology, demonstrate that NEXIUM® (esomeprazole magnesium) can reduce upper ... i-newswire.com

Clincal trials indicate NEXIUM® can reduce upper GI symptoms in …  -  May 12, 2005
...published in the American Journal of Gastroenterology, demonstrate that NEXIUM® (esomeprazole magnesium) can reduce upper gastrointestinal (GI) symptoms ... eurekalert.org

POZEN Confirms ANDA Filing for Treximet(R) Tablets  -  Oct 17, 2008
...in adults, and with AstraZeneca for proprietary fixed dose combinations of naproxen with the proton pump inhibitor esomeprazole magnesium in a single ... Genetic Engineering News - Genetic Engineering News (press release)

Pharmaceutical patent round-up  -  Nov 22, 2007
...pellet tablets (MUPS) formulation (EP 723 437), used in the company's drugs Nexium (esomeprazole magnesium) and Losec (omeprazole), was still valid. ... In-PharmaTechnologist.com

Brand Names/Synonyms:
Esomeprazole magnesium is also known by the following brand names and/or synonymsAntra; Antra Mups; Audazol; Aulcer; Belmazol; CCRIS 7099; Ceprandal; Danlox; Demeprazol; Desec; Dizprazol; Dudencer; Elgam; Emeproton; Epirazole; Erbolin; Esomeprazole; Esomeprazole Magnesium; Exter; Gasec; Gastrimut; Gastroloc; Gibancer; H 168/68; HSDB 3575; Indurgan; Inhibitron; Inhipump; Lensor; Logastric; Lomac; Losec; Mepral; Miol; Miracid; Mopral; Morecon; Nexium; Nexium Iv; Nilsec; Nopramin; OMEP; OMEPRAZOLE; OMP; OMZ; Ocid; Olexin; Omapren; Omebeta 20; Omed; Omegast; Omepral; Omeprazol [Inn-Spanish]; Omeprazole; Omeprazole [Usan:Ban:Inn:Jan]; Omeprazolum [Inn-Latin]; Omeprazon; Omeprol; Omesek; Omezol; Omezolan; Omid; Omisec; Omizac; Ompanyt; Ortanol; Osiren; Ozoken; Paprazol; Parizac; Pepticum; Pepticus; Peptilcer; Prazentol; Prazidec; Prazolit; Prilosec; Prilosec Otc; Procelac; Proclor; Prysma; Ramezol; Regulacid; Result; Sanamidol; Secrepina; Tedec Ulceral; Ulceral; Ulcesep; Ulcometion; Ulcozol; Ulcsep; Ulsen; Ultop; Ulzol; Victrix; Zefxon; Zegerid; Zepral; Zimor; Zoltum

Drug Category:
Esomeprazole magnesium is categorized under the following by the FDA: Anti-ulcer Agents; Proton-pump Inhibitors; ATC:A02BC01; ATC:A02BC05

Dosage Forms:
Oral tablets

Absorption:
Absorption is rapid, Absolute bioavailability (compared to intravenous administration) is about 30-40% at doses of 20-40 mg

Interactions:
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Chemical IUPAC Name:
5-methoxy-2-[(4-methoxy-3,5-dimethyl-pyridin-2-yl)methylsulfinyl]-3H-benzoimidazole





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