Fansidar

This page contains recent news articles, when available, and an overview of Fansidar but does not offer medical advice. You should contact your physician with regard to any health issues or concerns.


Overview:

Fansidar
(when available)

Pharmacology and use:
Pyrimethamine is an antiparasitic compound commonly used as an adjunct in the treatment of uncomplicated, chloroquine resistant, P. falciparum malaria. Pyrimethamine is a folic acid antagonist and the rationale for its therapeutic action is based on the differential requirement between host and parasite for nucleic acid precursors involved in growth. This activity is highly selective against plasmodia and Toxoplasma gondii. Pyrimethamine possesses blood schizonticidal and some tissue schizonticidal activity against malaria parasites of humans. However, the 4-amino-quinoline compounds are more effective against the erythrocytic schizonts. It does not destroy gametocytes, but arrests sporogony in the mosquito. The action of pyrimethamine against Toxoplasma gondii is greatly enhanced when used in conjunction with sulfonamides. For the treatment of toxoplasmosis and acute malaria; For the prevention of malaria in areas non-resistant to pyrimethamine

Mechanism Of Action:
Pyrimethamine inhibits the dihydrofolate reductase of plasmodia and thereby blocks the biosynthesis of purines and pyrimidines, which are essential for DNA synthesis and cell multiplication. This leads to failure of nuclear division at the time of schizont formation in erythrocytes and liver.

News Articles on Pyrimethamine

Doctor wins Shs300m grant for malaria research  -  ‎Dec 22, 2009‎
Currently, Fansidar is the drug used in malaria prevention during pregnancy, but there are fears that the parasite is becoming resistant to this drug. ... Daily Monitor

Malaria: desperate prevention measures  -  ‎Dec 26, 2009‎
Dr Mbewe said the government in treatment was using coartem, fansidar and quinine among others for the treatment of malaria. “Anything else from these ... postzambia.com

Aumento de casos de malaria preocupa autoridades sanitarias  -  ‎Dec 19, 2009‎
Para invertir el actual cuadro, Enoque Chivala dijo que están en curso acciones de prevención, con la administración de "Fansidar" (antipalúdico) a las ... AngolaPress

Pharmacist charged over drugs forgery  -  ‎Nov 6, 2009‎
Dan Tusubira, who resides in Banda, a Kampala suburb, is accused of forging chloroquine, quinine, metakelfin and fansidar. The prosecution told the ... New Vision

At least 10 years for new malaria drug  -  ‎Nov 6, 2009‎
The Artemisinin Based Combination Therapy (ACT) is the only recommended anti-malarial drug, after sulphur based medicines like fansidar which were ... Capital FM

The Problem with Generic Medicines in the Third World  -  ‎Nov 7, 2009‎
This time, it wasn't due to fake artesunate, but involved another drug, Fansidar.( SP or sulfadoxine-pyrimethamine). This drug's been around for awhile, ... Blogger News Network (blog)

Gates Foundation's Influence Criticized  -  Feb 16, 2008
Since it is not safe or practical to give Fansidar constantly to babies because it is a sulfa drug that can cause rare but deadly reactions and because ... New York Times

Ask Science  -  Jun 30, 2006
In Africa, where there are millions of malaria cases, resistance to chloroquine is widespread, while resistance to Fansidar, the brand name for a ... New York Times

World Briefing | Europe Belgium: Shipments of Fake Pills Seized  -  Oct 2, 2008
Blister packs of the pills, above, which included counterfeits of Tramal, a painkiller, and of Fansidar, an antimalaria drug, were found in large bags, ... New York Times

Kenya: Malaria Drug Was Ineffective, Says Ngilu  -  Apr 4, 2006
Nairobi — The Government was forced to replace the drug Fansidar with Coartem ... Speaking in Mombasa yesterday, the minister said Fansidar was replaced in ... AllAfrica.com

How charity fights killer.  -  Dec 14, 2005
Equally serious is the fact that resistance to the two drugs used, chloroquine and fansidar, is growing but the only effective alternative - Artemisinin ... Free with registration - Europe Intelligence Wire - AccessMyLibrary.com

Govt to distribute cheap anti-malaria drugs to private clinics  -  Sep 18, 2008
Otaala said the subsidised drugs were intended to phase out chloroquine and fansidar, saying malaria parasites had become resistant to them ... New Vision

Uganda: Some Districts Still Use Chloroquine  -  Jul 10, 2007
..."Scarcity of the drug has forced people to resort to chloroquine and fansidar, which have scientifically been proven not to be as effective as before." ... AllAfrica.com

Kenya: State Phases Out Sulphur-Based Malaria Drugs  -  Apr 20, 2006
Some of the SPs widely used in Kenya include Metakelfin and Fansidar. "It is worrying to hear that out of every four persons treated, one will not recover ... AllAfrica.com

Uganda: Mulago Medics Linked to Theft of Medicine  -  Jan 16, 2008
Coartem is a drug which thegovernment introduced in 2006 to treat malaria after Chloroquine and Fansidar that had been widely used by Ugandans for many ... AllAfrica.com

Government labels free drugs  -  Oct 23, 2008
The commonly stolen drugs are coartem and fansidar, which cure malaria, measles vaccine, Depo Provera for family planning, ORS for diarrhoea and ... New Vision

Kenya: African Examples  -  Mar 10, 2007
The antifolate drugs of interest were Fansidar and Lapdap, a new antifolate ... While working on Fansidar and Lapdap, he started to look into other uses of ... AllAfrica.com

Tanzania Standard Newspapers|Home  -  Jul 9, 2008
The minister told the House that the government stopped the prescription of other medicines like chloroquine, fansidar and others because they had failed to ... DailyNewsOnline

Older drugs may be good stopgap treatment for malaria in Africa  -  Jan 24, 2006
However, the Fansidar-artesunate combination was more effective than the other ... Bukirwa and Critchley say Fansidar-amodiaquine may be a useful stopgap ... eurekalert.org

Older Drugs May Be Good Stopgap Treatment For Malaria In Africa  -  Jan 26, 2006
However, the Fansidar-artesunate combination was more effective than the other ... Bukirwa and Critchley say Fansidar-amodiaquine may be a useful stopgap ... Medical News Today - Medical News Today (press release)

Belgian Customs Seize Record Haul of Fake Pills from India  -  Oct 3, 2008
...pharmaceutical company Grunenthal, and Swiss-based Roche's antimalarial treatment Fansidar -- were discovered in large bags, the customs service said. ... IndustryWeek

Angola: Les femmes enceintes prennent du "Fansidar" comme …  -  Mar 19, 2005
Luanda — L'anti-paludique "Fansidar" est le médicament que les femmes enceintes prendront comme prophylaxie, à partir du mois d'avril prochain, ... AllAfrica.com - allafrica.com

Europe pharma: Largest fake drug haul in Europe from India  -  Oct 10, 2008
The two products targeted by the counterfeiters were: Fansidar (pyrimethamine sulfadoxine), an antimalarial made under license from Swiss drug major Roche; ... $34.00 - EIU Country Analysis - Alacra Store

Madagascar: Paludisme - le « fansidar » pour préserver les nouveau-nés  -  Jul 13, 2007
Trois doses de Fansidar (Sulfadoxine-Pyriméthamine ou SP) permettraient de prémunir le nouveau-né du paludisme pour sa première année de vie. ... AllAfrica.com - allafrica.com

Prospects for slashing the impact of malaria with old drug  -  Aug 21, 2005
Fansidar is a 20-year-old malaria drug. As with many other such curative drugs, ... But initial clinical evidence suggests that Fansidar could have a new ... i-newswire.com

Le Fansidar fait son chemin dans la lutte contre le paludisme chez...  -  Oct 5, 2007
Non seulement les femmes enceintes tant dans le milieu urbain que rural ont adopté la molécule, mais les effets secondaires sont rares. ... Kaba Bachir

Potensi Peredaran Obat Palsu di Maluku Sangat Besar  -  Apr 8, 2005
Fansidar termasuk jenis obat keras dan hanya bisa dijual di apotik. ... "Kalau memang terbukti benar fansidar yang dijual di apotek di Masohi itu palsu, ... Detikcom

Renewed hope in Roche's malaria drug  -  Aug 19, 2005
A new clinical trial of Roche's malaria drug Fansidar is set to begin in Papua New ... But initial clinical evidence suggests that Fansidar could have a new ... Pay-Per-View - Datamonitor News and Comment - Factiva, from Dow Jones

Recordvangst namaakpillen op Brussels Airport  -  Oct 2, 2008
Het grootste deel van de inbeslaggenomen pillen waren Fansidar-pillen. "Dankzij deze inbeslagname zijn er levens gered", zegt Muylaert. ... Het Laatste Nieuws

CROI: Use of both cotrimoxazole and insecticide-treated bednets …  -  Mar 7, 2007
At the same time, CTX is closely related to other antifolate antimalarials, such as Fansidar, and the use of CTX against malaria could be complicated by ... Aidsmap

Top award for malaria scientist  -  Oct 10, 2006
Fansidar, an antifolate treatment, is used to inhibit the production of folate molecules to prevent malaria from multiplying but the malaria parasite can ... BBC News

Co-trimoxazole in Malawi: risks may outweigh benefits  -  Aug 24, 2005
The efficacy of Fansidar could be assessed in 53 cases of malaria where the ... Co-artemether has been proven more effective than Fansidar in a setting of ... Aidsmap

malaria research award  -  Oct 19, 2006
By comparing the role of these vitamins in the two diseases, Dr Nzila was able to understand how they aid resistance to a popular malaria drug, Fansidar. ... Wellcome Trust

Saisie record de pilules contrefaites au Brussels Airport de Zaventem  -  Oct 2, 2008
Il s'agit de médicaments de la marque Tramal, un analgésique de la société pharmaceutique Grunenthal, et de la marque Fansidar, comprimés antimalaria de ... Le Vif/L'Express - Le Vif/L'Express

Le Fansidar fait son chemin dans la lutte contre le paludisme chez...  -  Oct 10, 2008
Les dernières statistiques des établissements hospitaliers guinéens montrent selon un cadre du ministère de la santé et de l'hygiène publique, ... Kaba Bachir

Zambia: Zambia Commemorates Africa Malaria Day  -  Apr 24, 2005
When asked about Coartem, Ms Muswankila said: "We are given Fansidar when we go to the clinic although it makes us weak and that is why we are appealing for ... AllAfrica.com

… chez les femmes enceintes guinéennes : le Fansidar fait ses preuves  -  Apr 4, 2008
Le Fansidar met ainsi fin à la suprématie de la chloroquine dans le ... Le Fansidar, qui a un mode de libération prolongé semble mieux adapté pour remplacer ... Kaba Bachir

Uganda: Experts Warn On Coartem  -  Nov 28, 2006
This led to change of policy in 2000 where a combination of chloroquine and fansidar were encouraged but again a 21.4% resistance was noted. ... AllAfrica.com

3 held over fake malaria drugs  -  Nov 28, 2008
The suspects were also arrested with counterfeit Metakelfin drugs. Police say the suspects have been packing two tablets of fansidar in a Metakelfin packet. ... Daily Monitor

Fatal inaction: there is a silver bullet for Africa's malaria...  -  Jul 1, 2006
When he contracted malaria last week, she gave him Fansidar, a commonly ... He's had malaria twice in the past two months, and also took Fansidar, ... Free with registration - Washington Monthly - AccessMyLibrary.com

WHO official complains about Gates Foundation's dominance in malaria ...  -  Nov 7, 2008
Since it is not safe or practical to give Fansidar constantly to babies because it is a sulfa drug that can cause rare but deadly reactions and because ... New York Times

Roundup: Uganda steps up fight against malaria  -  Apr 26, 2005
..."Chloroquine and fansidar are no longer effective against the disease. They are facing a lot of resistance," said Rwakimari. ... People's Daily Online

WHO official criticizes Gates Foundation 'cartel' on malaria research  -  Feb 18, 2008
Since it is not safe or practical to give Fansidar constantly to babies because it is a sulfa drug that can cause rare but deadly reactions and because ... New York Times

Kenya: The Seedy Drug Wars  -  Jan 8, 2007
Metakelfin and Fansidar used to cost about Sh60 per dose, but ACTs manufactured by multinationals used to cost about Sh2,500 a dose before the Global Fund ... AllAfrica.com

Lưu dấu ngày xưa - Kết  -  Nov 16, 2008
Ba viên Fansidar như thần dược đã cắt hẳn cơn sốt kéo dài trong tôi suốt mấy năm li�n. Riêng bệnh dạ dày thì đã có thuốc của Thu làm giảm được cơn đau. ... DCV Online

Rwanda: Drug Crisis Hits Country  -  Feb 9, 2007
Look, there is no more Cotexin, Fansidar or quinine, ... We had a problem with drugs like chloroquin, fansidar cotexin and the like because the malaria ... AllAfrica.com

WHO official complains about Gates Foundation Malaria research risks ...  -  Feb 18, 2008
Since it is not safe or practical to give Fansidar constantly to babies because it is a sulfa drug that can cause rare but deadly reactions and because ... Pay-Per-View - International Herald Tribune - HighBeam Research

Article: Malaria chief at WHO faults Gates Foundation - International...  -  Feb 19, 2008
Since it is not safe or practical to give Fansidar constantly to babies because it is a sulfa drug that can cause rare but deadly reactions and because ... Pay-Per-View - International Herald Tribune - HighBeam Research

The Observer Media Ltd. :: The Weekly Observer :: Uganda's Top …  -  May 10, 2006
The number of pregnant women using Fansidar to prevent malaria has also risen from ... Government policy has since changed from Chroloquine and Fansidar to ... Observer - The Observer

Zambia: Malaria - Will It Ever Be Eradicated?  -  Mar 14, 2007
Veronica's first choice treatment of Fansidar failed to cure her condition and had to resort to Coartem drug. In the course of the month of December 2006, ... AllAfrica.com

Does Gates group have monopoly on malaria?  -  Feb 23, 2008
Because it is not safe or practical to give Fansidar constantly to babies -- it is a sulfa drug that can cause rare but deadly reactions -- and because ... Minneapolis Star-Tribune - Minneapolis Star Tribune

Uganda: Anti-Malarials - What Drug Works Best?  -  Aug 14, 2008
Some will buy fansidar, others artemether. There are different antimalarial drugs such as fansidar, chloroquine, quinine, coartem, lumartem, artequine, ... AllAfrica.com

VOA NEWS: BURUNDI TACKLES MALARIA USING NEW DRUG …  -  Apr 25, 2006
In the past, drugs called chloroquin and fansidar were used to treat malaria, ... "But before, it was around 70 percent by fansidar, by chloroquin. ... Pay-Per-View - US Fed News - Factiva, from Dow Jones

Uganda: Coartem Use for Malaria Deferred  -  Nov 5, 2006
So we have agreed to reduce ordering for Fansidar and Chloroquine, a combination for homapak, to have the ones in stock distributed and exhausted before we ... AllAfrica.com

Uganda: New Malaria Drug Free  -  Feb 22, 2006
The new drug, which falls under the newly- adopted Artemisinin-based combination treatments, is to replace chloroquine and fansidar as a first line ... AllAfrica.com

25 aprile, giornata mondiale contro la Malaria.  -  Apr 24, 2007
...“Prima di lavorare con MSF usavo la clorochina e il Fansidar per trattare la malaria. Circa 5 paziento su 10 non rispondevano a questi medicinali e ... Medici Senza Frontiere

New malaria treatment out  -  Mar 4, 2006
Muhwezi said the existing chloroquine and fansidar drugs would be used concurrently until stocks are depleted. Coartem is being procured through the Global ... New Vision

Ugandan turns to shrub for producing malaria drug.  -  Jul 26, 2005
26--KAMPALA -- Uganda will launch a new antimalarial drug combination to replace the common chloroquine plus fansidar or quinine drugs, which have become ... Free with registration - Kyodo News International - AccessMyLibrary.com

Uganda: Why Pregnant Women Need Antenatal Care  -  Feb 8, 2006
Nabirye said those with HIV/AIDS get three tablets of Fansidar thrice because of their low immunity. "We are diagnosed for any conditions that can affect ... AllAfrica.com

PulseCareers: Time out working in a rural African health centre.  -  Sep 6, 2007
I tried to limit indiscriminate prescribing of chloroquine and fansidar. The main changes to medical practice I made were simple ones, as I was conscious ... Free with registration - Pulse - AccessMyLibrary.com

Ugandan Turns to Shrub for Producing Malaria Drug  -  Jul 28, 2005
26--KAMPALA -- Uganda will launch a new antimalarial drug combination to replace the common chloroquine plus fansidar or quinine drugs, which have become ... RedOrbit

Govt sets guidelines to check distribution of expired drugs  -  Jul 18, 2008
...“This followed scientific studies on the effectiveness of chloroquine and fansidar as recommended by the World Health Organisation,� he observed. New Vision

Newborn safety measures acceptable but remain unpracticed  -  Oct 1, 2008
It is always frustrating when women get only three tablets of fansidar (the appropriate treatment). “I was given three fansidars and they are at home. ... Daily Monitor

Rwanda: Pharmacies Under Investigation Over Fake Malaria Drugs  -  May 29, 2008
Except for Fansidar which is soon to be banned, the health official said that the other two drugs (Coartem and Mefloquine) are imported under our quality ... AllAfrica.com

Zambia: The Fight Against Malaria  -  Apr 26, 2006
Unfortunately, the high levels of resistance of up to 64 per cent in some cases forced the government to start using Fansidar. Again, the resistance to ... AllAfrica.com

BOPA Daily News Archive  -  Jan 25, 2008
New first line Malaria treatment drug that replaces Fansidar known as Coartem is due for use in Botswana as from the 2008 Malaria season, he said adding ... www.gov.bw

The Observer Media Ltd. :: The Weekly Observer :: Uganda's Top …  -  May 4, 2006
Not only does Artemisinin cost over 10 times more than Fansidar and Chloroquine, its supply is still limited. According to the PEAP document, Uganda could ... Observer - The Observer

São Tomé e Príncipe lança novos antipalúdicos  -  Mar 1, 2005
As combinações artesunato-amodiaquina e artemeter-lumefrantine vão substituir a cloroquina eo fansidar, até aqui medicamentos de primeira e segunda ... panapress.com

Ouganda: le gouvernement prêt à distribuer les médicaments …  -  Sep 20, 2008
M. Otaala a noté que ces médicaments subventionnés ont pour objectif d'éliminer progressivement la chloroquine et le fansidar car les parasites du paludisme ... XINHUA

Cameroun: Femmes enceintes : la quinine ou rien  -  Apr 26, 2006
Contre le paludisme, les médecins préconisent ce médicament qui se présente sous forme de Fansidar, Maloxine, ou Paloxine comme unique traitement. ... AllAfrica.com - allafrica.com

Information drive aims to combat UK complacency about malaria  -  May 16, 2005
...sleeping under a mosquito net at night when the insects are most active and taking correctly prescribed prophylac tics such as Fansidar, ... guardian.co.uk

Mozambique: Malaria Consortium Chairperson Visits  -  Sep 24, 2007
Mozambique is committed to switching to Artemisinin-based Combination Therapy (ACT), and phasing out the previous drugs such as fansidar. ... AllAfrica.com

Label drugs - activists  -  Dec 3, 2007
He listed the drugs most stolen as coartem and fansidar for malaria, measles vaccine, Depo Provera for family planning, ORS for diarrhoea and cotrimaxazole ... New Vision

::Cameroun | Camer.be , l'information claire et nette ::Cameroon  -  Oct 3, 2008
La plupart des médicaments étaient des Fansidar. « Grâce à cette saisie, on a sauvé des vies », dit M. Muylaert. L'attention des douaniers avait été attirée ... Camer.be

Journée africaine contre le paludisme: Butembo peaufine des stratégies...  -  Apr 25, 2006
Toutefois, l'administration du fansidar aux femmes enceintes, la campagne sur l'utilisation de la moustiquaire imprégnée et l'assainissement du milieu ... Radio Okapi

Saisie de médicaments contrefaits à Zaventem  -  Oct 6, 2008
La plupart des médicaments étaient des Fansidar. « Grâce à cette saisie, on a sauvé des vies », dit M. Muylaert. L'attention des douaniers avait été attirée ... leTogolais.com

Drug-makers to withdraw single-drug malaria treatment  -  May 12, 2006
...ministry of health announced on Friday that it was changing its treatment policy from the less effective combination of chlorine and fansidar to ACTs. ... New Scientist

Rwanda: Country Reduces Malaria Deaths By Half  -  Sep 20, 2008
The use of Artemisinin-based Combination Therapy (ACT) recommended by WHO to replace previously used anti-malarials such as Fansidar and Chloroquine has ... AllAfrica.com

An Iron Fist Joins the Malaria Wars  -  Jun 27, 2006
Since then, DDT has been withdrawn because of its environmental damage, chloroquine and its successor, Fansidar, have become all but useless and the health ... New York Times

The enemy is malaria. The cure is £25  -  Apr 25, 2008
Part of the reason is that the drugs - a combination of chloroquine and Fansidar - have now been replaced nationally by the World Health ... guardian.co.uk

Chloroquin imports to stop in December  -  Oct 2, 2007
Even when chloroquin was used in combination with fansidar, it failed to cure 30% of the patients, Lugemwa said. The Government decision was based on both ... New Vision

Uganda: Uganda: Anti-DDT Lobby Could Slow Fight Against Malaria, …  -  Apr 25, 2005
..."Chloroquine and fansidar are no longer effective against malaria," he told IRIN on Friday. He added that part of the $66-million the country recently ... AllAfrica.com

Nigeria: Onitsha Drug Market is a National Embarrassment, says...  -  Apr 3, 2007
Others were clones of fast moving and costly drugs (ie Halfan, Fansidar, Septrin, Ampiclox, Ciprxin, Diflucan, Nizoral); thermolabile drugs like Tetanus ... AllAfrica.com

New Malarial Therapy Reaches Remote Africa  -  Nov 2, 2005
The Health Ministry has decided to use artemisinin in combination with other drugs rather than the old mainstays -- chloroquine and fansidar -- which have ... NPR

AT&T Finds a Temporary Home; Woods's Event Set to Shift to Suburban …  -  Oct 7, 2008
The doctors studied brand names for antibiotics and found seven categories that included allusions ... only to the maker" (Fansidar, Anspor, Symmetrel). ... Pay-Per-View - Washington Post - HighBeam Research

Uganda: Flowers And Frowns  -  Oct 3, 2007
Dr Sendagire was part of the team that researched on why malaria in Uganda was becoming resistant to chloroquin and Fansidar and later prescribed cortem. ... AllAfrica.com

Uganda: Global Fund Hailed in Fight Against HIV, Malaria  -  Dec 7, 2005
..."It has also allowed prompt case management of patients and increase the number of pregnant women who receive two doses of Fansidar. ... AllAfrica.com

'Kiyingi accused had been drugged'  -  Sep 19, 2006
He said Atwine also complained of cough, chest pain, headache and fever and the diagnosis was malaria for which he received chloroquin, panadol and fansidar. New Vision

Make new laws to fight fake drugs  -  Oct 31, 2008
...stated on the package such as Paracetamol tablet ingredients packaged and fraudulently labeled as fansidar (sulphadoxine and pyrimethamine combination). ... The Punch

Fake malaria drugs on sale  -  May 16, 2008
The drugs sampled were sulfadoxine-pyromethamine (commonly known as fansidar), amodiaqine (commonly known as camaquin), mefloquine, artesunate, artemether, ... New Vision

Uganda: Ministry Distributes Coartem  -  Apr 17, 2006
...of Health has distributed the new malaria drug, Coartem, to districts in order to stop the use of the parasite-resistant chloroquine and fansidar. ... AllAfrica.com

Uganda battles problem of counterfeit drugs  -  Sep 13, 2008
The drugs tested included amodiaqine (camaquin), sulfadoxine-pyromethamine (fansidar), and coartem. A similar study was done in Uganda's neighbours (Kenya, ... Daily Monitor

Hospitals lack drugs, says survey  -  Dec 14, 2008
Medicine like amoxicillin capsules, septrin tablets and diclofenac tablets, gentamycin injection, fansidar, quinine injection and tetracycline eye ointment. ... New Vision

Uganda: Label Free Drugs, Health Ministry Urged  -  Oct 19, 2008
The commonly stolen drugs are Coartem and Fansidar for malaria, the measles vaccine, Depo Provera for family planning, ORS for diarrhoea and Cotrimaxazole ... AllAfrica.com

Uganda: Health Ministry Imports Stronger Malaria Drug  -  Feb 3, 2006
Coartem, the first fixed-dose combination of artemether and lumefantrine, is the first line treatment against malaria, replacing chloroquine and fansidar. ... AllAfrica.com

Without DDT spraying malaria will kill more  -  May 20, 2008
This can be anything from traditional herbal medicine through dangerously ineffective but cheap combination therapies like chloroquine and fansidar, ... New Vision

Uganda: Govt Must Focus On Malaria Prevention  -  Sep 21, 2008
The subsidised drugs are intended to phase out chloroquine and fansidar that have ceased to be effective in treating malaria. ... AllAfrica.com

Uganda: Gulu Monitors Drug  -  Apr 3, 2006
Coartem will replace Chloroquine and Fansidar in the treatment of malaria. Every year, Gulu records 320000 cases of malaria, most of them from the ... AllAfrica.com

Kenya: Drive to Curb Drug Resistance  -  Apr 28, 2006
Mr Chepkwony identified sulpha-based drugs like Fansidar and Metakelfin, and painkillers containing paracetamol, as the most abused by counterfeiters, ... AllAfrica.com

Hope looms in fight against malaria  -  Nov 16, 2008
Up until recently, monotherapy drugs like chloroquine and fansidar were used to treat malaria but have over the years developed resistance. ... Daily Monitor

Uganda: More Drugs to Expire - NMS  -  Oct 13, 2006
They said the government's erratic switch to a new Malaria drug regime (Coartem) is to blame for the huge stockpile of the traditional Fansidar and ... AllAfrica.com

Kenya: Killer Malaria Gets Its Match, Free of Charge  -  Sep 27, 2006
Even Sulphadoxine-Pyrimethamine (SP) drugs such as Fansidar and Metakelfin - which the ACTs are replacing - will continue selling at local outlets. ... AllAfrica.com

Nigeria: Partnering to Tame Malaria Scourge  -  May 22, 2007
Although the company is a pharmaceutical manufacturing and marketing one with a wide range of anti-malarials like FANSIDAR (and FANSIMEF), as well as ACTs ... AllAfrica.com

Uganda: Ministry of Health Changes Malaria Treatment Strategy  -  May 12, 2006
Kampala — The Ministry of Health has changed the malaria treatment policy from the lesser effective combination of chlorine and fansidar to a more effective ... AllAfrica.com

In Brief  -  Dec 22, 2005
KAMPALA — A new malaria drug called Coartem is going to replace fansidar and chloroquine for the treatment of severe malaria, an official of the Uganda ... New Vision

Malaria Drug Lowers Anemia, Improves Attention Span in Children  -  Jul 10, 2008
Researchers from London, Boston, and Kenya looked at whether treatment with Roche's Fansidar and Sanofi-Aventis' Flavoquine would reduce anemia, ... Bloomberg

Brand Names/Synonyms:
Fansidar is also known by the following brand names and/or synonyms4753 R.P.; BW 5063; CD; Chloridin; Chloridine; Chloridyn; Darachlor; Daraclor; Darapram; Daraprim; Daraprime; Diaminopyritamin; Disulone; Erbaprelina; Ethylpyrimidine; Fansidar; Khloridin; Malacid; Malocid; Malocide; Maloprim; NSC-3061; Pirimecidan; Pirimetamin; Pirimetamina; Primethamine; Pyremethamine; Pyrimethamin; Pyrimethamine; Pyrimethamine Hcl; RP 4753; Tindurin; Tinduring; WR 2978

Drug Category:
Fansidar is categorized under the following by the FDA: Antiprotozoals; Antimalarials; Folic Acid Antagonists; ATC:P01BD01

Dosage Forms:
TABLET

Absorption:
Well absorbed with peak levels occurring between 2 to 6 hours following administration

Interactions:
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Chemical IUPAC Name:
5-(4-chlorophenyl)-6-ethyl-pyrimidine-2,4-diamine





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