Fenfluramine

This page contains recent news articles, when available, and an overview of Fenfluramine but does not offer medical advice. You should contact your physician with regard to any health issues or concerns.


Overview:

Fenfluramine
(when available)

Pharmacology and use:
Used to treat diabetes and obesity, Fenfluramine decreases caloric intake by increasing serotonin levels in the brain’s synapses. Fenfluramine acts as a serotonin reuptake inhibitor. It also causes release of serotonin from the synaptosomes. For the management of exogenous obesity as a short-term (a few weeks) adjunct in a regimen of weight reduction based on caloric restriction.

Mechanism Of Action:
Fenfluramine binds to the serotonin reuptake pump. This causes inhbition of serotonin uptake and release of serotonin. The increased levels of serotonin lead to greater serotonin receptor activation which in turn lead to enhancement of serotoninergic transmission in the centres of feeding behavior located in the hypothalamus. This suppresses the appetite for carbohydrates.

News Articles on Fenfluramine

Abrupt end to eating, drinking and being merry  -  ‎Jan 4, 2010‎
Among other diet drug “mistakes� were thyroid hormone, which caused hyperthyroidism; fenfluramine, linked to heart valve abnormalities; ... Irish Times

Health ministry bans obesity drug rimonabant following reports of side effects  -  ‎Dec 28, 2009‎
In 1998, the government had prohibited imports of two anti obesity drugs – fenfluramine and dexfenfluramine – which was the last time when government ... pharmabiz.com

Brain serotonin-2 receptors in acute mania  -  ‎Dec 31, 2009‎
Neuroendocrine studies have reported unaltered prolactin responses to buspirone and dl-fenfluramine, growth hormone responses to sumatriptan, ... British Journal of Psychiatry

Valvulopathies iatrogènes : retrait du marché du benfluorex (Médiator)  -  ‎Dec 18, 2009‎
En 1997, le médicament est retiré du marché mondial ainsi que tous les dérivés fenfluraminiques comme la fenfluramine (Pondéral). ... theheart.org/fr

Những thuốc gây hại cho mắt  -  ‎Dec 14, 2009‎
Một số biệt dược như simvastatin, fenfluramine, các thuốc chống co thắt dạ dày, một số thuốc chống trầm cảm cũng bị nghi ng� là có thể gây ra glôcôm. ... Tin nhanh

Benfluorex (Médiator°) :un amphétaminique à bannir  -  ‎Dec 10, 2009‎
...qui ont conduit au retrait du marché de 2 autres amphétaminiques anorexigènes : la fenfluramine (ex-Pondéral°) et de dexfenfluramine (ex-Isoméride°). ... Vie Femme

Lorcaserin, nouvelles données sur la pilule lorcaserin de Arena  -  14 Nov 2009
La pilule lorcaserin fonctionne d'une manière similaire à la fenfluramine. Lorcaserin est conçu pour bloquer les signaux d'appétit dans le cerveau, ... RegimesMaigrir.com

The Mulligan Law Firm is Investigating Injury Claims: The Weight Loss Drugs ...  -  ‎Oct 23, 2009‎
It is a combination of two drugs: fenfluramine and phentermine. Not approved by the FDA ("off label"), it was nevertheless widely prescribed as the result ... PR Web (press release)

Nurse took Fen-phen, Diagnosis PPH  -  ‎Oct 26, 2009‎
...(Pondimin is the brand name for fenfluramine. Fen phen, which was withdrawn from the market in 1997, is a combination of fenfluramine and phentermin. ... Lawyers and Settlements

Brand and Generic ADIPEX (Phentermine). FDA approved. Fast Delivery ...  -  ‎Oct 31, 2009‎
Metric conversions are as a single daily administered before fenfluramine. During or within a phentermine with few weeks. Primary pulmonary hypertension. ... Newstalk ZB

Arena: 2nd weight loss trial shows cardiac benefit  -  ‎Oct 27, 2009‎
Lorcaserin works in a way similar to fenfluramine, which was part of the fen-phen diet cocktail before it was withdrawn in 1997 after being linked to heart ... Reuters India

Going Off-label Without Venturing Off-Course  -  ‎Oct 26, 2009‎
For example, fenfluramine hydrochloride and phentermine hydrochloride were approved by the FDA as individual agents for short-term use in the medical ... Archives of Internal Medicine

Companies Race To Bring Diet Drugs To Market  -  ‎Oct 28, 2009‎
The medicine stimulates a receptor in the brain that curbs appetite while sparing a related receptor in the heart that was the downfall of fenfluramine, ... NPR

PPH and Fen-Phen Research Ongoing  -  ‎Nov 7, 2009‎
Although the disease is rare, it is 100 times more likely to occur among former users of Fen-Phen and other fenfluramine drugs like Redux and Pondimin. ... Lawyers and Settlements

Phentermine para adelgazar, contraindicaciones  -  ‎Nov 10, 2009‎
Tampoco pueden ingerirlo los que tomen fenfluramine (Phen-Fen) o dexfenfluramine (Redux), anorexígenos, ya que en estos casos se estarían arriesgando a ... Nutricion.pro

上海交大教授获新è?¯ç ”ç©¶æ–°æˆ?æžœ  -  ‎Nov 4, 2009‎
Antinociceptive properties of fenfluramine, a serotonin reuptake inhibitor, in a rat model of neuropathy. J. Pharmacol. Exp. Ther. 291: 1008-1016. 33. ... 生物通

ANALYSIS-Arena Obesity Drug Emerges from Shadow of Fen-Phen  -  Mar 18, 2008
Pondimin and Redux, also known as fenfluramine and dexfenfluramine, were withdrawn more than a decade ago, but Wyeth, which has spent billions of dollars ... Reuters

Fat Chances  -  May 11, 2005
That combo of two medicines, fenfluramine and phentermine, ... Fenfluramine was withdrawn from the market, resulting in massive legal costs for drugmaker ... Forbes

Banned Obesity Drug Tied to Heart Risks Long After Use  -  Nov 7, 2008
The appetite suppressant fenfluramine has been banned in the United States ... In all, 0.44 percent of these former fenfluramine users had valve surgery ... Washington Post

Abuse of prescribed slimming drug seen in HK  -  Jun 1, 2007
But the Food and Drug Administration banned fenfluramine, and a related drug, dexfenfluramine, ... Fenfluramine and dexfenfluramine were made by Wyeth (WYE. ... Reuters

Wyeth Says Popular Drugs Spurred Gains  -  Apr 22, 2006
...litigation over the drugs, chemical cousins that were the fenfluramine half of the fen-phen diet-drug combination that was popular in the mid-1990's. New York Times

… Court Opinions - IN RE DIET DRUGS (PHENTERMINE/FENFLURAMINE) …  -  May 25, 2005
IN RE DIET DRUGS (PHENTERMINE/FENFLURAMINE) (EDPa. 2005) 381 F. Supp.2d 421 IN RE: DIET DRUGS (Phentermine/Fenfluramine/Dexfenfluramine) PRODUCTS LIABILITY ... Pay-Per-View - Loislaw Federal District Court Opinions - Loislaw

Wright v. American Home Products Corp., No. 06-CV-4183-NKL (WDMo. …  -  Apr 18, 2008
This case involves alleged injuries suffered by Plaintiff Becky Wright as a result of ingesting fenfluramine, marketed as Pondimin, by its manufacturer(s) ... $2.95 - U.S. District Court, Western District... - VersusLaw

Judge awards fees of $414M in diet case  -  Apr 10, 2008
Madison, NJ-based pharmaceutical maker Wyeth, formerly known as American Home Products, produced fenfluramine, half of the diet drug cocktail known as ... Boston Globe

Weight cycling alters the effects of D-fenfluramine on susceptibility...  -  Feb 1, 2006
It has been proposed that anorexia nervosa (AN) is treatable with serotonergic (5-HT) agonists. It seems paradoxical to treat a disorder characterized by ... Am J Clin Nutr (subscription)

The anorectic effect of fenfluramine is influenced by sex and stage...  -  Jan 5, 2005
The controls of food intake differ in male and female rats. Daily food intake is typically greater in male rats, relative to female rats, and a decrease in ... AJP-Regul Integr Comp Physiology...

The Health Page: Unofficial 'diet pills': Drugs to treat epilepsy,...  -  Sep 3, 2006
...(Fenfluramine had been commonly given to patients along with phentermine, another appetite suppressant; the combination, which was never approved by the FDA ... $2.95 - Chicago Sun-Times - NewsBank

… Administrative Code - CSB 2.03 Addition of fenfluramine to...  -  Jul 16, 2005
CSB 2.03 Addition of fenfluramine to schedule IV. The substance known as fenfluramine is hereby added to s. 161.20, Stats., schedule IV in sub. ... Pay-Per-View - Wisconsin Administrative Code - Loislaw

Dopamine agonists and valvular heart disease: the unknown unknowns.( …  -  Apr 1, 2007
Fenfluramine (the racemic mixture of dexfenfluramine plus levofenfluramine) had been ... But fenfluramine and dexfenfluramine are not ergot derivatives. ... Free with registration - Brown University Psychopharmacology... - AccessMyLibrary.com

Trial may change duties of pharmacy  -  Sep 17, 2008
By September of that year, the FDA asked the manufacturers of fenfluramine to voluntarily withdraw it from the market. But patient Steve Downing, ... $2.95 - Salt Lake Tribune, The - NewsBank

Man pleads guilty to importing banned drug  -  Sep 10, 2005
They allegedly imported fenfluramine from England from October 1999 to ... Officials banned fenfluramine from the US market in 1997 after a series of ... $2.95 - Kansas City Star - NewsBank

Louisiana Fen Phen Lawyer Johnson Sees Increase in Primary …  -  Jun 6, 2007
According to the American Heart Association, the drug fenfluramine was taken off the market in September 1997 after being linked to heart valve damage. ... Web Services Journal - Web Services Journal

Anorexia Nervosa; Fenfluramine accelerates weight loss from activity-...  -  Apr 26, 2005
2005 APR 26 - (NewsRx.com) -- Fenfluramine treatment in female rats accelerates the weight loss associated with activity-based anorexia. ... Pay-Per-View - Life Science Weekly - Factiva, from Dow Jones

Appetite suppressants, the big hope, the big letdown .  -  Jan 11, 2006
The combination of phentermine and fenfluramine or were pre scribed for thousands of people ... In 1997 fenfluramine and were with drawn from the US market, ... Aberdeen Times - Google News Archive

Effect of clozapine on d-fenfluramine-evoked neuroendocrine responses...  -  Mar 1, 2008
BACKGROUND. Clozapine is an effective antipsychotic that has high affinity for serotonin type 2 (5-HT2) receptors. The importance of 5-HT antagonism in the ... British Journal of Psychiatry (subscript...

TODAY IN HISTORY .  -  Sep 15, 2007
Ten years ago: Two of the nation's most popular diet drugs — dexfenfluramine and fenfluramine — were pulled off the market because of new evidence they ... Times Daily - Google News Archive

Mobile - News, Events, Restaurants, Music from Phoenix - Phoenix New ...  -  Aug 25, 2006
...(The "Fen" referred to the appetite depressant fenfluramine, and the "Phen" to phentermine. Both are amphetamines.) Chernov had been suffering from severe ... Phoenix New Times

Anorexia Nervosa; Fenfluramine accelerates weight loss from activity-...  -  Apr 28, 2005
2005 APR 28 - (NewsRx.com) -- Fenfluramine treatment in female rats accelerates the weight loss associated with activity-based anorexia. ... Pay-Per-View - Women's Health Weekly - Factiva, from Dow Jones

Researchers find clue to safer obesity drugs  -  Nov 27, 2008
...“Conventional wisdom is that fenfluramine increases serotonin release that then activates serotonin receptors in the brain to regulate food intake and body ... Insciences Organisation

Houston Law Firms Win Fen-Phen Verdict.  -  Mar 27, 2006
In 1997, the Food and Drug Administration announced the withdrawal of fen- phen, named for a combination of the drugs fenfluramine and appetite- suppressant ... Free with registration - PR Newswire - AccessMyLibrary.com

Illinois Administrative Code - 77 Ill. Adm. Code 2070.2400 Fenfluramin...  -  Aug 10, 2005
77 Ill. Adm. Code 2070.2400 Fenfluramine Any material, compound, mixture, or preparation which contains any quantity of the following substances, ... Pay-Per-View - Illinois Administrative Code - Loislaw

Serotonergic function in children with ADHD linked to later antisocial...  -  Aug 1, 2007
Using blood samples of 7- to 11-year old children, the investigators measured plasma prolactin levels in response to fenfluramine, which is an index of ... Free with registration - Brown University Child and Adolescent... - AccessMyLibrary.com

Progress in settling Wyeth diet drug claims.(Brief Article)  -  Mar 7, 2005
...by the firm's previously-marketed fenfluramine slimming drugs) have agreed to participate in a proposed process for settling downstream opt-out cases, ... $4.95 - Pharma Marketletter - ECNext

Wisconsin Administrative Code - CSB 2.11 Renumbering and addition to ...  -  Jul 16, 2005
161.20, Stats., schedule IV is hereby renumbered to read: (b) Fenfluramine Paragraph (a) of sub. (2m), s. 161.20, Stats., schedule IV is hereby created to ... Pay-Per-View - Wisconsin Administrative Code - Loislaw

医è?¯ä¸€å‘¨ï¼šâ€œä¼ªè?¯å“?â€?纷纷è?½é©¬æ€€å­•“惨案â€?屡è§?报端  -  Jul 31, 2008
...澳门特区近日�布公告说,根�香港�生署的公告,产�“新康散�掺�有西��份“西布曲 明(sibutramine)��“氟苯丙胺(fenfluramine)�。澳门�生局的资料显示,上述产�从 ... 人民网

盘点å‡?è‚¥è?¯ä¹?ç§?副作用(图)  -  Mar 22, 2007
...芬芬也是一�食欲抑制剂,其主��分之一就是芬弗拉明(fenfluramine)。 美国食��物 管�局于1997 年9 月就正��止将芬芬用于�肥的用途,这是因为�芬芬的�肥�� ... 浙江在线

Challenges in the Discovery and Development of New Agents for the …  -  Mar 21, 2007
Starting in 1994, sales of phentermine and fenfluramine increased dramatically. ... Valvular heart disease associated with fenfluramine-phentermine. ... Nature.com

Woman's death highlights risk of herbal diet products  -  Aug 16, 2005
Fenfluramine was banned in the United States in 1997 after being linked to ... In Hong Kong, fenfluramine was deregistered in 1998 after being linked to ... The Standard

Coupe-faim et anorexigènes et risque d'hypertension artérielle …  -  Mar 16, 2006
C'est notamment le cas de la fenfluramine et de la dexfenfluramine. Largement utilisées, notamment en Europe et aux États-Unis pour lutter contre le ... Actualités News Environnement

香港四種纖體產å“?å?«è¥¿è—¥æˆ?份有副作用  -  Sep 29, 2006
Fenfluramine以往曾被用以抑制食慾,以�減肥效果。有科學研究顯示,Fenfluramine與 心瓣疾病有關,因此香港於一��八年起撤銷�這種�份的西藥註冊。 epochtimes.com

Loislaw Federal District Court Opinions - MADSEN v. AMERICAN HOME …  -  Mar 7, 2007
Plaintiff was prescribed fenfluramine and dexfenfluramine by Timothy J. Miller, ... Plaintiff alleges that at the time she ingested fenfluramine and ... Pay-Per-View - Loislaw Federal District Court Opinions - Loislaw

Loislaw Federal District Court Opinions - IN RE DIET DRUGS …  -  Apr 8, 2008
During the period from March to August, 1997 the Mayo Clinic in Rochester, Minnesota observed and reported an association between the use of fenfluramine ... Pay-Per-View - Loislaw Federal District Court Opinions - Loislaw

Loislaw Federal District Court Opinions - CAVENDER v. AMERICAN …  -  May 7, 2007
Page 2 Phentermine and fenfluramine ("Phen-fen")[fn3] were prescribed for Plaintiff by ... She attributes her alleged injuries to her use of fenfluramine. ... Pay-Per-View - Loislaw Federal District Court Opinions - Loislaw

Serotonergic Stimulation of Adrenocorticotropin Secretion in Man *  -  Jun 1, 2005
We gave normal men three oral doses (0.5, 1.0, and 1.5 mg/kg) of fenfluramine, a serotonin-releasing agent and uptake inhibitor, and a corresponding placebo ... Journal of Clinical Endocrinology and...

HK experts warn against "herbal" slimming products  -  Jun 11, 2007
Laboratory tests of these products found they contained N-nitrosofenfluramine, an analogue of fenfluramine, and N-desmethyl-sibutramine, an analogue of ... Reuters

Experimental obesity drug of Arena Pharmaceuticals expected to clear ...  -  Mar 6, 2008
Arena says its drug, like fenfluramine, blocks appetite signals in the brain ... Fenfluramine, which was tied to heart failure and a fatal lung disorder, ... New York Times

HK experts warn against "herbal" slimming products  -  Jun 12, 2007
Laboratory tests of these products found they contained N-nitrosofenfluramine, an analogue of fenfluramine, and N-desmethyl-sibutramine, an analogue of ... Reuters India

å?«é™?血壓西藥æˆ?分/ 「壯腎之寶ã€?須回收  -  Jul 26, 2008
...署亦呼籲市民ä¸?è¦?購買或æœ?用一種å??為「新康散ã€?的減肥產å“?,因為產å“?被發ç?¾å?«æœªç¶“ 註冊西藥æˆ?分「西布曲明ã€?(sibutramine)å?Šå°‘é‡?「氟苯丙胺ã€?(fenfluramine)。 ... takungpao.com

WYETH IS CLOSER TO RESOLVING SUITS ; DRUG MAKER, PLAINTIFF …  -  Jan 19, 2005
Wyeth, a major Richmond-area employer, made Pondimin, the fenfluramine half of fen-phen, and Redux, a chemical cousin. Pondimin was made only in Richmond. ... Pay-Per-View - Richmond Times - Dispatch - ProQuest Archiver

å?±éšªè—¥ç¼ºè¨˜éŒ„/ 西醫罰款四è?¬  -  Oct 28, 2008
...衛生署在今年一月在被告�於銅鑼���仔診所,發�大��未經註冊西藥氟 苯丙胺(Fenfluramine)��引致心臟病發並致命的減肥藥丸膠囊,證實�沒有�照第一部藥表的 ... takungpao.com

法庭簡訊/ 先科案å?„被告續ä¿?  -  Jul 11, 2008
...上市纖體公�修身堂旗下西醫張英傑,�衛生署�發涉嫌今年一月在銅鑼���仔診所, �有大��未經註冊西藥氟苯丙胺(Fenfluramine)��引致心臟病發並致命的減肥藥丸 ... takungpao.com

NJ Launches Campaign for Better Health | Article from AP Online | …  -  Nov 15, 2006
Three New Jersey women are suing the company on behalf of 94000 New Jerseyans who took the pills. AHP -- which made fenfluramine, the ``fen'' half of the . ... Pay-Per-View - Associated Press/AP Online - HighBeam Research

å?°å°¼å¥³å­?誤食減肥藥出幻覺  -  Aug 28, 2008
...化驗çµ?果顯示,該產å“?å?«æœ‰ã€Œè¥¿å¸ƒæ›²æ˜Žã€?(sibutramine)å?Šã€Œæ°Ÿè‹¯ä¸™èƒºã€?(fenfluramine) , 兩種æˆ?分會引致嚴é‡?副作用。 產å“?據稱從å?°å°¼å¸¶ä¾†é¦™æ¸¯ï¼Œè©²å??女å­?從朋å?‹è™•購得。 ... 雅虎香港

Obesity Pharmacotherapy from a Regulatory Perspective: Overview and …  -  Mar 28, 2007
26 Unfortunately, in the case of fenfluramine–phentermine, one component of the combination (fenfluramine) was associated with unexpected serious adverse ... Nature.com

減肥產å“?å?«æœªè¨»å†Šè¥¿è—¥æˆ?分  -  Jul 25, 2008
...投訴,懷疑該產�所�的�分,隨�展開調查,�得產�樣本作化驗,今日化驗�果 顯示產��有「西布曲明�(sibutramine)�少�「氟苯丙胺�(fenfluramine)。 ... 雅虎香港

In re Diet Drugs Products, No. 02-4020 (3d Cir. 03/10/2005)  -  Mar 10, 2005
See Press Release, FDA, FDA Announces Withdrawal of Fenfluramine and Dexfenfluramine (Fen-Phen) (Sept. 15, 1997). Subsequent studies suggested that the ... $2.95 - U.S. Court of Appeals, Third Circuit - VersusLaw

There's still no magic pill for weight loss  -  Feb 19, 2006
Some say the field remains shaken by the FDA's decision to pull fenfluramine and dexfenfluramine from the market in 1997. The combination known as fen-phen ... Boston Globe

Maryland Code - § 5-405 CRIM. LAW Controlled dangerous substances: …  -  Aug 18, 2005
...(c) Fenfluramine. — Substances listed in Schedule IV include: (1) a material, compound, mixture, or preparation that contains fenfluramine; and (2) if its ... Pay-Per-View - Maryland Code - Loislaw

Arena's obesity drug fares well in early tests But questions remain...  -  Mar 7, 2008
Arena says its drug, like fenfluramine, blocks appetite signals in the brain ... Fenfluramine, which was tied to heart failure and a fatal lung disorder, ... Pay-Per-View - International Herald Tribune - HighBeam Research

UT Southwestern researchers find clue to safer obesity drugs  -  Nov 25, 2008
..."Conventional wisdom is that fenfluramine increases serotonin release that then activates serotonin receptors in the brain to regulate food intake and body ... eurekalert.org

Nationaal > PAS OP MET CHINESE KRUIDEN  -  Sep 9, 2005
In alle verpakkingen die men in beslag nam, kwam fenfluramine en/of nitroso-fenfluramine voor, maar in sterk verschillende hoeveelheden. ... Dagblad Suriname

Clue To Safer Obesity Drugs: Mechanism Links Serotonin With …  -  Dec 7, 2008
..."Conventional wisdom is that fenfluramine increases serotonin release that then activates serotonin receptors in the brain to regulate food intake and body ... sciencedaily.com

PILS Compliance Columnist  -  Jan 13, 2005
Fen-phen refers to the use in combination of fenfluramine and phentermine. Fenfluramine acts through serotonergic mechanisms resulting in a feeling of ... honeycombconnect.com

Trattamento dell'obesità: diversi farmaci sono stati ritirati dal...  -  Apr 11, 2006
Problemi di sicurezza hanno comportato il ritiro di Aminorex, delle fenfluramine nel 1997 e della Fenilpropanolamina nel 2000. ... XagenaSalute

First of Merck's many court days  -  Jul 11, 2005
Wyeth, the maker of fenfluramine, a diet drug that withdrawn from the market ... Wyeth's seemingly unending payments to settle fenfluramine cases have led ... New York Times

New Jersey Superior Court Reports - IN RE DIET DRUG LITIGATION, 384 …  -  Apr 7, 2005
The updated warning included the following: Fenfluramine has been reported ... In these reports and other reported cases, fenfluramine was generally taken ... Pay-Per-View - New Jersey Superior Court Reports - Loislaw

Worth the weight? ; People desperate to lose extra pounds are turning...  -  Aug 23, 2006
...(Fenfluramine had been commonly given to patients along with phentermine, another appetite suppressant; the combination, which was never approved by the FDA ... Pay-Per-View - Chicago Tribune - ProQuest Archiver

Unequal Treatment; How African Americans have often been the …  -  Jan 7, 2007
In the 1990s, African American youths in New York were injected with Fenfluramine -- half of the deadly, discontinued weight loss drug Fen-Phen -- by ... Pay-Per-View - Washington Post - ProQuest Archiver

Improvements in sexual quality of life after moderate weight loss  -  Apr 28, 2008
This was due in large part to the cessation of the trial when adverse cardiac effects associated with the use of phentermine--fenfluramine were identified. ... Nature.com

[U] Fisher v. Teva Pfc Srl, 212 Fed.Appx. 72 (3d Cir. 12/22/2006)  -  Dec 22, 2006
In 1997, in order to control Wanda Fisher's weight problem, a Utah physician prescribed Ms. Fisher a drug containing Fenfluramine and Phentermine, ... $2.95 - U.S. Court of Appeals, Third Circuit - VersusLaw

Drug withdrawals from the Canadian market for safety reasons, 1963- …  -  Mar 15, 2005
It took over 25 years (October 1970 to September 1997) before it was recognized that fenfluramine was associated with cardiac valve abnormalities. ... Free with registration - CMAJ: Canadian Medical Association... - AccessMyLibrary.com

Digital Chosunilbo (English Edition) : Daily News in English About...  -  Sep 11, 2005
The Korean consulate in Shanghai said Sunday some of the slimming medication available in China without a prescription contain fenfluramine, a proscribed ... 조선�보 - 조선�보(�문�)

Retired Drugs: Failed Blockbusters, Homicidal Tampering, Fatal …  -  Oct 1, 2008
Taken alone, Redux (which was dexfenfluramine, a derivative of fenfluramine) produced drowsiness and mood swings. But when patients accompanied Redux with ... Wired News

Leading Doctor Cites Obesity Drugs in Attack on FDA Approval Process  -  Nov 8, 2005
..."Fenfluramine was known to cause pulmonary hypertension that could be fatal, and its d-isomer was expected to do so as well. "But despite this risk, ... Acomplia Report

Acomplia Report - ADP356 Said Effective in Short Preliminary Trial  -  Nov 8, 2005
The new pill thus bears some similarities to the diet combination of fenfluramine and phentermine (fen-phen), in that fenfluramine also worked by increasing ... Acomplia Report

Health Canada: Avoid Energy II, Apisate, Obat Asam Urat, Asam Urat  -  Aug 22, 2008
Energy ll contained sibutramine and Apisate contained fenfluramine. ... Fenfluramine, also used in the treatment of obesity, is currently prohibited for ... emaxhealth.com

Painkiller in the dock  -  Jul 28, 2005
Wyeth, another drug firm based in New Jersey, has so far paid $21 billion in charges related to lawsuits filed by people who took its diet drug fenfluramine ... Nature.com

Article: Appetite suppressants, the big hope, the big letdown - New...  -  Jan 18, 2006
Clinical psychologist Armond Aserinsky ... which he founded after his wife contracted PH from fen-phen. Its fenfluramine component was pulled ... ... Pay-Per-View - New York Beacon, The - HighBeam Research

Burton v. Wyeth-Ayerst Laboratories Division of American Home...  -  Apr 9, 2007
These products contained the drugs fenfluramine and dexfenfluramine, ... 719 (1998) (concluding that exposure to fenfluramine or dexfenfluramine for four ... $2.95 - U.S. District Court, Northern District... - VersusLaw

United States 3rd Circuit Court of Appeals Reports - IN RE DIET DRUGS...  -  Nov 30, 2005
2005) In re: DIET DRUGS (PHENTERMINE/FENFLURAMINE/DEXFENFLURAMINE) PRODUCTS LIABILITY LITIGATION Clara Clark, Linda Smart and all other class members ... Pay-Per-View - United States 3rd Circuit Court of... - Loislaw

First of Merck's many court days | Article from International Herald...  -  Jul 11, 2005
Wyeth, the maker of fenfluramine, a diet drug that withdrawn from the market ... Wyeth's seemingly unending payments to settle fenfluramine cases have led ... Pay-Per-View - International Herald Tribune - HighBeam Research

Article: First of Merck's many court days - International Herald...  -  Jul 11, 2005
Wyeth, the maker of fenfluramine, a diet drug that withdrawn from the market ... Wyeth's seemingly unending payments to settle fenfluramine cases have led ... Pay-Per-View - International Herald Tribune - HighBeam Research

Louisiana Acts - ACT NO. 56 OF 2006  -  May 16, 2006
...position, or geometric), and salts of isomers, whenever the existence of such salts, isomers, and salts of isomers including Fenfluramine is possible. ... Pay-Per-View - Louisiana Acts - Loislaw

'Rethinking Thin' and the Myths, Realities of Dieting  -  May 23, 2007
The pill turned out to be phen-fen, for phentermine-fenfluramine. It was a combination of an appetite suppressant (phentermine) and a drug that not only ... NPR

Montana Statutes - 50-32-229. Specific dangerous drugs included in …  -  Aug 5, 2005
...(3) Fenfluramine. Any material, compound, mixture, or preparation that contains any quantity of fenfluramine, including its salts, isomers (whether optical, ... Pay-Per-View - Montana Statutes - Loislaw

Search for obesity drugs still looks golden  -  Nov 9, 2008
Eleven years ago, the search for an obesity drug ran into controversy when fenfluramine, an appetite suppressant, was banned in the United States over fears ... Independent Online

Despite failures, search for obesity drugs still looks golden  -  Nov 16, 2008
Eleven years ago, the search for an obesity drug ran into controversy when fenfluramine, an appetite suppressant, was banned in the US over fears of its ... eTaiwan News

United States 3rd Circuit Court of Appeals Reports - IN RE DIET DRUGS...  -  Mar 10, 2005
In re: DIET DRUGS (PHENTERMINE/FENFLURAMINE/DEXFENFLURAMINE) PRODUCTS ... See Press Release, FDA, FDA Announces Withdrawal of Fenfluramine and ... Pay-Per-View - United States 3rd Circuit Court of... - Loislaw

Canadian drug safety system is inadequate, has no "withdrawn" list,...  -  Mar 21, 2005
For example in 2000, nefazodone was the 118th most-prescribed drug in Canada, while fenfluramine was the 190th most-prescribed in 1996 and pemoline was used ... $4.95 - Pharma Marketletter - ECNext

The risky business of off-label use: off-label use of drugs and...  -  Mar 1, 2005
Ironically, the FDAMA was enacted only two months after the popular diet drugs fenfluramine and dexfenfluramine were withdrawn from the market because of ... $4.95 - Trial - ECNext

Some drugs gain popularity for weight-loss effects  -  Aug 22, 2006
...(Fenfluramine had been commonly given to patients along with phentermine, another appetite suppressant; the combination, which was never approved by the FDA ... Pittsburgh Post-Gazette - Pittsburgh Post Gazette

All that wobbles is market gold to some eyes  -  Sep 4, 2006
In the mid-1990s, Time published a cover story on the "magic" new drug combination of phentermine and fenfluramine (affectionately referred to as phen-fen). ... Sydney Morning Herald

Despite failures, search for obesity drugs still looks golden  -  Nov 17, 2008
Eleven years ago, the search for an obesity drug ran into controversy when fenfluramine, an appetite suppressant, was banned in the United States over fears ... ABS CBN News

Comparison of combinations of drugs for treatment of obesity: body …  -  Aug 30, 2005
The combination of phentermine, an adrenergic agent, and fenfluramine, a serotonergic ... Fenfluramine is no longer available because it was associated with ... Nature.com

Arena Son of Fen-Phen Shows Promise That Eluded Wyeth  -  Nov 21, 2007
In 1996, Wyeth began selling Redux, a tablet that combined Wyeth's fenfluramine, approved in 1973, and the generic drug phentermine, on the market since ... Bloomberg

Appetite downer awaits approval  -  Sep 29, 2005
A case in point is the fenfluramine–phentermine combination popularly called ... Its fenfluramine component suppressed appetite by boosting serotonin levels ... Nature.com

In re Briscoe, 448 F.3d 201 (3d Cir. 05/15/2006)  -  May 15, 2006
...[68], The clinical and epidemiological studies demonstrate -- and all the experts agree -- that insofar as the use of fenfluramine or dexfenfluramine ... $2.95 - U.S. Court of Appeals, Third Circuit - VersusLaw

Suddenly sick: Rush to new weight-loss drugs zaps patients' health.  -  Jul 7, 2005
It also stopped selling Pondimin, its brand-name fenfluramine, half of the phen-fen combo. Melum said her doctor, Nadine Burrington in Mount Vernon, ... Free with registration - Seattle Times - AccessMyLibrary.com

Florida Statutes - 893.03 Standards and schedules. —  -  Aug 3, 2005
...(w)[fn1] Fenfluramine. (x) Fenproporex. (y) Fludiazepam. (z) Flurazepam. ... 97-1 , added paragraph (4)(w) listing fenfluramine. Section 5, ch. ... Pay-Per-View - Florida Statutes - Loislaw

13,000 weight-loss pills seized in raid  -  Jun 1, 2007
Fenfluramine, commonly referred to as "FenPhen,'' was withdrawn from the US market in 1997 by the US Food and Drug Administration, after research linked it ... $2.95 - The Sun - NewsBank

Slim, trim and playing with fire  -  Aug 29, 2005
In Hong Kong, pharmaceutical products containing fenfluramine were de- registered in 1998. But slimming aids containing the drug can still be found in Hong ... Pay-Per-View - The Standard - Factiva, from Dow Jones

The Health Page: Unofficial 'diet pills': Drugs to treat epilepsy,...  -  Sep 3, 2006
...(Fenfluramine had been commonly given to patients along with phentermine, another appetite suppressant; the combination, which was never approved by the FDA ... Pay-Per-View - Chicago Sun-Times - HighBeam Research

Article: EXPERTS WEIGH IN ON NEW OVER-THE-COUNTER DIET PILL.( …  -  Jun 15, 2007
The new diet pill Redux could be next to face scrutiny in the wake of reports linking ... fenfluramine. But Dr. Harold Solomon, a Beth Israel Deaconess ... Pay-Per-View - Cincinnati Post - HighBeam Research

VIRGINIA / Massey names Grinnan to two top positions  -  May 25, 2006
Wyeth, a major Richmond-area employer, made Pondimin, the fenfluramine half of fen-phen, and Redux, a chemical cousin. Pondimin was made only in Richmond. ... Pay-Per-View - Richmond Times - Dispatch - ProQuest Archiver

Article: Wyeth to finance research as part of diet drug deal - The...  -  Aug 23, 2005
Wyeth made the drug Pondimin, which is generically known as fenfluramine. Pondimin was used with another non-Wyeth drug, phentermine, as part of the ... Pay-Per-View - The Record - HighBeam Research

In re: Diet Drugs Products Liability Litigation, No. 99-20593 (EDPa....  -  Nov 16, 2007
...*fn3 "Fen-Phen" is widely used to refer to the combination of the diet drugs Fenfluramine and Phentermine. Fenfluramine, marketed under the brand name ... $2.95 - U.S. District Court, Eastern District... - VersusLaw

Brand Names/Synonyms:
Fenfluramine is also known by the following brand names and/or synonymsAcino; Adipomin; CHEMBANK1560; Dea No. 1670; F1884; Fenfluramina [Dcit]; Fenfluramine; Fenfluramine Hydrochloride; Fenfluraminum [Inn-Latin]; HSDB 3080; Obedrex; Pesos; Ponderax Pa; Ponderex; Pondimin; Rotondin; S 768

Drug Category:
Fenfluramine is categorized under the following by the FDA: Serotonin reuptake inhibitor; Anorexigenic Agents; Stimulants; ATC:A08AA02; ATC:A08AA04

Dosage Forms:
TABLET

Absorption:
Not Available

Interactions:
[an error occurred while processing this directive]



Chemical IUPAC Name:
N-ethyl-1-[3-(trifluoromethyl)phenyl]-propan-2-amine





Health Home | Conditions | Cancer | Medications | Surgery | Vaccines


The Cancer News Network


Disclaimer:

Contact a physician with regard to health concerns. Email requests for further health information will be discarded.

The materials contained on this Web site are for informational purposes only and do not constitute health or medical advice. Use of information on this site does not create or constitute any kind of agreement or contract between you and the owners or users of this site, the owners of the servers upon which it is housed, or anyone else who is in any way connected with this site.

Many links on cancernewsnetwork.org lead to other sites. cancernewsnetwork.org does not sponsor, endorse or otherwise approve of the materials appearing in such sites. Nor is CancerNewsNetwork.org responsible for dead or misdirected links.

IF YOU NEED A LINK OR TEXT REMOVED FROM THIS PAGE PLEASE CONTACT cancernewsnetwork (at) live.com.
We will do our best to accommodate your request.



COPYRIGHT 2009 CANCERNEWSNETWORK | Privacy