Fenofibrate

This page contains recent news articles, when available, and an overview of Fenofibrate but does not offer medical advice. You should contact your physician with regard to any health issues or concerns.


Overview:

Fenofibrate
(when available)

Pharmacology and use:
Fenofibrate is a lipid regulating agent indicated as adjunctive therapy to diet to reduce elevated LDL-C, Total-C,Triglycerides and Apo B, and to increase HDL-C in adult patients with primary hypercholesterolemia or mixed dyslipidemia (Fredrickson Types IIa and IIb). Fenofibrate is also indicated as adjunctive therapy to diet for treatment of adult patients with hypertriglyceridemia (Fredrickson Types IV and V hyperlipidemia). Fenofibric acid, the active metabolite of Fenofibrate, produces reductions in total cholesterol, LDL cholesterol, apolipoprotein B, total triglycerides and triglyceride rich lipoprotein (VLDL) in treated patients. In addition, treatment with fenofibrate results in increases in high density lipoprotein (HDL) and apoproteins apoAI and apoAII. For use as adjunctive therapy to diet to reduce elevated LDL-C, Total-C,Triglycerides and Apo B, and to increase HDL-C in adult patients with primary hypercholesterolemia or mixed dyslipidemia (Fredrickson Types IIa and IIb)

Mechanism Of Action:
Fenofibrate exerts its therapeutic effects through activation of peroxisome proliferator activated receptor a (PPARa). This increases lipolysis and elimination of triglyceride-rich particles from plasma by activating lipoprotein lipase and reducing production of apoprotein C-III. The resulting fall in triglycerides produces an alteration in the size and composition of LDL from small, dense particles, to large buoyant particles. These larger particles have a greater affinity for cholesterol receptors and are catabolized rapidly.

News Articles on Fenofibrate

Comparison of the efficacy of administering a combination of ezetimibe plus ...  -  ‎Dec 17, 2009‎
Conclusions: The combination of ezetimibe plus fenofibrate appeared to produce nearly identical alterations in serum lipoprotein levels when compared to ... 7thSpace Interactive (press release)

International, Well-Known Scientific Experts Say That New GFT505 Data Unlikely ...  -  ‎Dec 16, 2009‎
These experts reaffirmed the continuing role of generic lipid-modifying treatments, fenofibrate and bezafibrate, in treating atherogenic dyslipidemia, ... PR Newswire (press release)

Cipher secures summary judgment in the company's favour in pending patent ...  -  ‎Jan 4, 2010‎
The Company's lead compound, CIP-FENOFIBRATE, received final approval from the US Food and Drug Administration and Health Canada in the first quarter of ... PR Newswire (press release)

Generic TriCor Agreement Allows Teva to Sell Early  -  ‎Dec 18, 2009‎
The deal giving Teva the right to market 145-mg tablets of generic TriCor (fenofibrate) in March 2011 was disclosed in an Abbott SEC filing last month. FDA news (subscription)

Abbott Labs' Deal with Teva Pharma Is 'Phat News' for Lipid-Lowering Franchise  -  ‎Dec 14, 2009‎
The settlement involves the 145 milligram dose of TriCor (fenofibrate), which is the cholesterol lowering drug's most popular strength. ... BNET

Steven A Kliewer and David J Mangelsdorf  -  ‎Dec 18, 2009‎
...hypertriglyceridemic patients had 2-fold elevated FGF21 concentrations, which were further increased by treatment with the PPAR agonist fenofibrate. ... Am J Clin Nutr (subscription)

ABT Seeks Simcor Label Expansion - Analyst Blog  -  ‎Dec 18, 2009‎
TriLipix was approved in December 2008 and should strengthen Abbott's position in the fenofibrate market. Abbott has been actively seeking to grow its ... Benzinga

LifeCycle Pharma secures Notice of Allowance for US patent for Fenoglide  -  ‎Dec 17, 2009‎
...issuance of a Notice of Allowance from the United States Patent and Trademark Office for the company's US patent application for its fenofibrate tablet. ... Trading Markets (press release)

Pharma's year of merger mania  -  ‎Dec 15, 2009‎
...for €4.5 billion (£4.0 billion) in September, giving it control of the cholesterol lowering drug fenofibrate it already uses in a combination product. ... Chemistry World

Kowa Pharmaceuticals America Announces the Divestment of CAMBIA™ and PRO-571  -  ‎Dec 14, 2009‎
Its lead product, LIPOFEN ® (fenofibrate capsules), is indicated as adjunctive therapy to diet to reduce elevated triglycerides and to increase HDL-C in ... Behavioral Health Central (blog)

Lilly, Kowa and Kowa Pharmaceuticals America Announce Co-Promotion and ...  -  ‎Dec 24, 2009‎
Its lead product, LIPOFEN® (fenofibrate capsules), is indicated as adjunctive therapy to diet to reduce elevated triglycerides and to increase HDL-C in ... PipelineReview.com (press release)

Abbott suing Impax Labs over generic TriCor  -  ‎Oct 30, 2009‎
Annual sales of TriCor, or fenofibrate, are more than $1 billion. The patents protecting TriCor will start to expire in January 2011, opening the door to ... The Associated Press

Fenofibrate May Protect Diabetics Against Loss of Renal Function: Presented at ...  -  ‎Nov 4, 2009‎
SAN DIEGO -- November 4, 2009 -- Long-term fenofibrate use may protect against the loss of underlying renal function in patients with ... DG News

Impax Laboratories Continues Trend of Solid Growth in Revenue, Profit and ...  -  ‎Nov 3, 2009‎
Net Global product sales increased 132% to $46.6 million, an increase of $26.6 million over the same period in 2008 primarily due to sales of fenofibrate ... WELT ONLINE

Cipher appoints Dr. William Claypool to Board of Directors  -  ‎Nov 3, 2009‎
The Company's lead compound, CIP-FENOFIBRATE, received final approval from the US Food and Drug Administration and Health Canada in the first quarter of ... Reuters

Kolasa: High triglycerides? Here are 10 tips that will help  -  ‎Nov 11, 2009‎
...your doctor will talk with you about taking a medication like nicotinic acid (Niacin), fibrates like Gemfibrozil (Lopid) and Fenofibrate (Tricor), ... Greenville Daily Reflector

Study Demonstrates LIVALO(R) Is an Efficacious Treatment for Achieving Lipid Goals  -  ‎Oct 22, 2009‎
Its lead product, LIPOFEN® (fenofibrate capsules), is indicated as adjunctive therapy to diet to reduce elevated TG and to increase HDL-C in adult patients ... Reuters

Cipher receives complaint of patent infringement for CIP-TRAMADOL ER  -  ‎Nov 2, 2009‎
The Company's lead compound, CIP-FENOFIBRATE, received final approval from the US Food and Drug Administration and Health Canada in the first quarter of ... Trading Markets (press release)

Cipher reports Q3 2009 financial results  -  ‎Nov 4, 2009‎
The Company's lead compound, CIP-FENOFIBRATE, received final approval from the US Food and Drug Administration and Health Canada in the first quarter of ... CNW Telbec (Communiqué de presse)

Expect substantial contribution from Antara: Lupin  -  ‎Oct 26, 2009‎
The overall market of Fenofibrate in US is about USD 2 billion. Therefore we do expect substantial growth of this brand in our hands and a very promising ... Moneycontrol.com

SOLVAY : Operating result in the third quarter (EUR 285 million) in line with ...  -  ‎Oct 28, 2009‎
Earnings for the fenofibrate franchise in the United States in 2009 were lower following the significant revenues in December 2008 (EUR 39 million) related ... ITnews.it

Nuevo aporte de la Fundación OSDE al Hospital Santamarina  -  ‎Nov 6, 2009‎
La contribución realizada, que se suma a otras efectuados durante el año, incluyó en esta ocasión 84 unidades de FENOFIBRATE 120mg Tablet 90's USP Fenoglide ... LU 22 Radio Tandil

General Alvear: "El Hospital municipal recibió donación de medicamentos de la ...  -  ‎Oct 29, 2009‎
En esta oportunidad el Hospital recibió: • 84 Unidades x 90 comprimidos de FENOFIBRATE 120 mg (Medicamento p/ control de colesterol y triglicéridos). ... PlusInformacion

Solvay says study shows favourable effect of Fenofibrate on type 2 …  -  Nov 14, 2005
BRUSSELS (AFX) - Belgian chemicals and pharmaceutical group Solvay said that a study showed a favourable impact of its Fenofibrate drug on preventing ... Forbes

Is combined treatment with fenofibrate and ezetimibe safe and...  -  Jun 1, 2006
McKenney JM et al. (2006) Safety and efficacy of long-term co-administration of fenofibrate and ezetimibe in patients with mixed hyperlipidemia. ... Nature.com

Diabetes Drug Helps Protect Patients' Eyes  -  Nov 7, 2007
7 (HealthDay News) -- In people with type 2 diabetes, the drug fenofibrate reduces the need for laser treatment for diabetic retinopathy, the leading cause ... Washington Post

What is the effect of fenofibrate on cardiovascular disease events in...  -  Feb 22, 2006
Keech A et al. (2005) Effects of long-term fenofibrate therapy on cardiovascular events in 9795 people with type 2 diabetes mellitus (the FIELD study): ... Nature.com

Solvay says study shows fenofibrate cuts risk of vision loss in type...  -  Nov 7, 2007
BRUSSELS (Thomson Financial) - Belgian chemicals and pharmaceuticals group Solvay SA said a clinical study showed that its fenofibrate drug reduces the need ... Forbes

Abbott Labs, Two Solvay Units Sued Over TriCor Drug  -  Mar 18, 2008
The drug is a fenofibrate, a type used to reduce triglycerides and cholesterol. ... In fact, there are eight other fenofibrate products available.'' ... Bloomberg

LifeCycle gets fenofibrate approval in US  -  Aug 13, 2007
By Katrina Megget, 13-Aug-2007. The lowest formulated dose of cholesterol-busting fenofibrate has been approved for the US market using a new formulation ... In-PharmaTechnologist.com

Fenofibrate May Help Thwart Cardiovascular Disease in Type 2 Diabetics...  -  Nov 15, 2005
By Jill Stein. DALLAS, TX -- November 15, 2005 -- The cholesterol drug fenofibrate appears to decrease the risk of cardiovascular events compared to placebo ... DG News

Coadministration of Ezetimibe-Simvastatin and Fenofibrate  -  Jul 28, 2006
Target lipid values are difficult to achieve in mixed hyperlipidemia -- a metabolic disorder characterized by the constellation of elevated low-density ... Medscape

FDA Approves Triglide(TM) A Novel Formulation of Fenofibrate  -  May 9, 2005
SkyePharma PLC announces today that the US Food and Drug Administration ('FDA') has approved Triglide(TM), its novel formulation of fenofibrate. ... Medical News Today - Medical News Today (press release)

Abbott settles lawsuit related to its cholesterol drugs  -  Nov 20, 2008
The company said it had also settled some other previously-disclosed lawsuits related to the cholesterol-lowering fenofibrate formulations. ... Reuters

Lilly cholesterol drug no better than TriCor-study  -  Mar 25, 2007
Despite the potency of this new drug -- it's about 10000 times stronger than TriCor -- researchers found it showed no advantages over fenofibrate, ... Reuters

Cipher receives FDA approval for Lipofen (CIP-Fenofibrate)  -  Jan 13, 2006
MISSISSAUGA, CANADA -- January 13, 2006 -- Cipher Pharmaceuticals Inc. today announced that it has received final approval from the US Food and Drug ... DG News

Solvay says Teva files for generic TriCor drug  -  Jan 24, 2008
...which was informed of the application, "remains fully committed to its fenofibrate franchise and is currently evaluating its options." ... Reuters

Abbott settles fight over patent on drug  -  Jun 9, 2005
Last month, Teva received FDA approval for its Fenofibrate tablets with ... Fenofibrate is the generic equivalent of TriCor, and the 54 milligram and 160 ... Pay-Per-View - Chicago Tribune - ProQuest Archiver

Fenofibrate Oral : User Ratings covering uses, effectiveness,...  -  Jul 18, 2008
Not sure, I take it at bed time with all my other meds? I realize now it has to be taken with a meal, which one not sure?? ... WebMD

Study shows fenofibrate reduces need for laser treatment for diabetic...  -  Nov 5, 2007
By Lancet, [RxPG] Treatment with fenofibrate in individuals with type 2 diabetes mellitus reduces the need for laser treatment for diabetic retinopathy (DR) ... RxPG NEWS

… Acquisition of Cardiovascular Therapy ANTARA(R) 130mg (Fenofibrate)...  -  Aug 21, 2006
Fenofibrate has been associated with increases in serum transaminases. ... Fenofibrate may increase cholesterol excretion into the bile, ... RedOrbit

Abbott set for battle over generic Tricor.  -  May 17, 2005
Teva Pharmaceutical Industries Ltd. received FDA clearance to sell fenofibrate tablets, the generic equivalent of Tricor, in 54- and 160-milligram doses. ... Free with registration - Chicago Tribune - AccessMyLibrary.com

Bloomberg Printer-Friendly Page  -  Sep 9, 2008
Diabetics taking the drug, also known as fenofibrate, were 38 percent less likely ... Fenofibrate, like statins, improves the health of large blood vessels. ... Bloomberg

Abbott investors shrug at drug report -  -  Jun 5, 2007
..."There is absolutely no new science or data to suggest that fenofibrate causes renal harm," said Abbott spokeswoman Melissa Brotz. ... $2.95 - Chicago Sun-Times - NewsBank

… Therapy ANTARA(R) 130 mg (fenofibrate) Capsules From Rel  -  Jul 24, 2006
Oscient Pharmaceuticals (Nasdaq: OSCI) has agreed to acquire US rights to the cardiovascular product ANTARA(R) 130 mg (fenofibrate) capsules from Reliant ... Free with registration - Business Wire - AccessMyLibrary.com

Skyepharma launches cholesterol drug Triglide in US  -  Jul 18, 2005
The treatment is based on the drug Fenofibrate, first introduced internationally in 1975. In its natural form it is virtually insoluble in water, ... Forbes

Simvastatin and Fenofibrate Reduces Cholesterol and Triglycerides in ...  -  Apr 3, 2007
..."We observed an average 52-mg decline in triglycerides when simvastatin was added to baseline treatment with fenofibrate," said Heidi May, MS, ... Diabetes In Control

Solvay's Fournier withdraws marketing application for Synordia - EMEA  -  Dec 8, 2006
...owned by Belgian chemicals group Solvay SA, was withdrawing its marketing authorisation application for Synordia (fenofibrate/metformin hydrochloride). ... Forbes

Combination of Simvastatin and Fenofibrate Reduces Cholesterol and …  -  Mar 28, 2007
By Ed Susman. NEW ORLEANS, LA -- March 28, 2007 -- The combination of cholesterol-lowering agents simvastatin and fenofibrate enhances the ability to reduce ... DG News

Fenofibrate Does Not Halt Atherosclerosis in Patients With Diabetes: ...  -  Apr 29, 2008
By Sara Freeman. ISTANBUL, Turkey -- April 29, 2008 -- Fenofibrate has no effect on atherosclerotic progression in patients with type 2 diabetes who are ... DG News

… and First Horizon extend agreement for novel formulation of fenofib...  -  Feb 1, 2005
Subject to FDA approval, the amended agreement would now permit First Horizon to launch the novel fenofibrate product in 1H 2005. ... Free with registration - Asia Africa Intelligence Wire - AccessMyLibrary.com

Fenofibrate (Systemic).(Drug overview)  -  Aug 1, 2006
Fenofibrate ( fen-o-FI-brate) is used to lower triglyceride (fat-like substances) levels and cholesterol levels in the blood. This may help prevent the ... Free with registration - USP DI-Volume II, Advice for the... - AccessMyLibrary.com

FIELD: Fenofibrate in diabetics  -  Sep 14, 2005
Dallas, TX - The fibrate hypolipemic fenofibrate failed to significantly reduce the primary end point (CHD death or nonfatal MI) vs placebo in diabetic ... Medscape

… Announce Selection of Next-Generation Fenofibrate ABT-335 and …  -  Aug 31, 2007
ABT-335 is Abbott's next-generation fenofibrate currently in late-stage clinical ... ABT-335 is a next-generation fenofibrate in clinical development for ... Free with registration - PR Newswire - AccessMyLibrary.com

Fenofibrate (Systemic).(Drug overview)  -  May 1, 2006
Fenofibrate ( fen-o-FI-brate) is used to lower triglyceride (fat-like substances) levels and cholesterol levels in the blood. This may help prevent the ... Free with registration - USP DI-Volume II, Advice for the... - AccessMyLibrary.com

Atorvastatin, Fenofibrate Fixed Combo Is Effective For Mixed Dyslipide...  -  Dec 22, 2008
A once-daily, fixed-dose tablet combining atorvastatin and a novel micronized formulation of fenofibrate outperformed either drug alone in a phase II ... Diabetes In Control

Novel therapy for lipid disorders shows mixed results in early...  -  Mar 27, 2007
In general, both LY518674 and fenofibrate were well tolerated, but the authors ... LY518674 and fenofibrate increased serum creatinine levels among patients ... Hindu

… when WelChol (colesevelam HCl) is added to fenofibrate in patients...  -  Oct 5, 2005
Following a 4-8 week washout period, participants received fenofibrate 160 mg/day for ... The combination of fenofibrate and WelChol had mean total LDL-C ... Pay-Per-View - Company Reports - Factiva, from Dow Jones

Fenofibrate showed no benefits for patients with type 2 diabetes  -  Dec 10, 2008
Treatment with fenofibrate had no effect on low-grade inflammation, endothelial activation, augmentation index or progression of carotid intima-media ... Endocrine Today

Fenofibrate cuts retinopathy in diabetic patients: those who were...  -  Dec 1, 2007
ORLANDO -- Treatment with fenofibrate led to a substantial drop in the need for laser treatments for retinopathy in a controlled trial of nearly 10000 ... Free with registration - Family Practice News - AccessMyLibrary.com

Ranbaxy, Ethypharm in pact  -  Sep 19, 2006
Fenofibrate is a drug prescribed to lower triglycerides in cases of Hyperlipidemia while Atorvastatin is a drug widely used to manage cholesterol levels, ... Hindu Business Line

… burn victims' recovery, diabetes, metabolism aided by fenofibrate...  -  Apr 3, 2005
..."We hoped that improving fat metabolism with fenofibrate, ... The patients were randomly assigned either to placebo or fenofibrate treatment after the first ... eurekalert.org

Effects of Short-Term Fenofibrate Treatment on Circulating Markers of...  -  Mar 1, 2008
Address all correspondence and requests for reprints to: Robert Krysiak, Department of Clinical Pharmacology, Medical University of Silesia, Medyków 18, ... Journal of Clinical Endocrinology and...

… Pharma A/S forms exclusive licensing agreement for fenofibrate in...  -  May 1, 2007
This agreement covers the marketing of fenofibrate in the US, ... Fenofibrate is prescribed for the treatment of hyperlipidemia and triglyceridemia. ... Free with registration - Nordic Business Report - AccessMyLibrary.com

… burn victims' recovery, diabetes, metabolism aided by fenofibrate...  -  Apr 4, 2005
..."We hoped that improving fat metabolism with fenofibrate, ... The patients were randomly assigned either to placebo or fenofibrate treatment after the first ... Medical News Today - Medical News Today (press release)

Cipher receives Health Canada approval of CIP-Fenofibrate.  -  Feb 20, 2006
MISSISSAUGA, ON, Feb. 20 /PRNewswire-FirstCall/ -- Cipher Pharmaceuticals Inc. (TSX: DND) today announced that it has received final approval from Health ... Free with registration - PR Newswire - AccessMyLibrary.com

… burn victims' recovery, diabetes, metabolism aided by fenofibrate...  -  Mar 30, 2005
..."We hoped that improving fat metabolism with fenofibrate, ... The patients were randomly assigned either to placebo or fenofibrate treatment after the first ... PsychCentral.com

Fish Oil Plus Fenofibrate Good for High Triglycerides  -  Dec 17, 2007
Fish oil supplements, combined with the lipid-lowering drug fenofibrate (Tricor), reduced triglycerides to normal levels in a significant percentage of ... AIDSmeds.com HIV/AIDS Treatment News

Utah study may help diabetics  -  Mar 13, 2006
All the study patients received dual therapy with simvastatin and fenofibrate, which both slow down production of cholesterol and triglycerides in the liver ... Deseret News

Two cholesterol drugs better than one for diabetics  -  Mar 25, 2008
Combination therapy plus fenofibrate shifted LDL cholesterol pattern B to a more buoyant LDL cholesterol that was less inclined to form plaques on the walls ... Reuters India

Tricor (fenofibrate) Aids Pediatric Burn Victims' Recover by Reducing...  -  Apr 12, 2005
One of the immediate serious results of sudden extreme trauma or stress, including burns and even surgery, is insulin resistance, or diabetes. ... Diabetes In Control

Fenofibrate - First Lipid Modifying Agent Shown to Protect Diabetic...  -  Jun 11, 2007
Fenofibrate is the first and only widely available lipid modifying agent to demonstrate significant protection to the eye of patients with type 2 diabetes, ... ITNews

Fenofibrate Intervention and Event Lowering in Diabetes (FIELD)  -  Feb 28, 2006
The goal of the trial was to evaluate treatment with fenofibrate compared with placebo among patients with diabetes at risk for coronary heart disease. ... Medscape

Two cholesterol drugs better than one for diabetics  -  Mar 24, 2008
Combination therapy plus fenofibrate shifted LDL cholesterol pattern B to a more buoyant LDL cholesterol that was less inclined to form plaques on the walls ... Reuters

International Approvals: Grazax and CIP-Fenofibrate  -  Mar 20, 2006
March 20, 2006 — The Swedish Medical Products Agency has approved a tablet-based immunotherapy for hay fever, and Health Canada has approved CIP-fenofibrate ... Medscape

Sciele to Work on Fenofibrate and Pravastatin Combination  -  Feb 6, 2007
Sciele Pharma entered into an agreement with Galephar Pharmaceutical Research to develop and market a combination of fenofibrate and pravastatin to treat ... Genetic Engineering News - Genetic Engineering News (press release)

Abbott drug doesn't prevent fatal heart attacks in diabetics - Nov....  -  Nov 14, 2005
Keech said that Tricor, also known as fenofibrate, could be used as an additive, not a replacement, to statins, the drugs used to control cholesterol levels ... CNNMoney.com

Press Release: Fenofibrate Reduces the Risk of Amputations in...  -  Sep 9, 2008
Fenofibrate Reduces the Risk of Amputations in Patients With Type 2 Diabetes.(Clinical report) from PR Newswire Europe. Highbeam Research – FREE Trial. Pay-Per-View - PR Newswire Europe - HighBeam Research

FDA Gives Final Approval to Fenofibrate Tablets  -  May 19, 2005
By Teva Pharmaceutical, [RxPG] Teva Pharmaceutical Industries Ltd. (Nasdaq: TEVA) announced today that the US Food and Drug Administration has granted final ... RxPG NEWS

FIELD: Mixed results found with fenofibrate therapy among patients...  -  Jan 1, 2006
DALLAS – Fenofibrate therapy for diabetes-specific lipid disorders produced mixed results, with a reduction in nonfatal myocardial infarction but no effect ... Endocrine Today

ProEthics licenses Lipofen to Cipher  -  Jul 11, 2007
..."Total fenofibrate prescriptions have increased strongly over the past several years, with US prescriptions rising 18 percent in 2006." United Press International

Fenofibrate Protects Against Diabetic Retinopathy  -  Nov 20, 2007
Patients with type 2 diabetes given fenofibrate for lipid lowering required significantly less laser treatment for retinopathy, investigators reported. ... Diabetes In Control

Fenofibrate reduces need for laser retinopathy treatment in diabetic ...  -  Nov 21, 2007
Treating patients with type 2 diabetes mellitus with fenofibrate reduces the need for laser treatment of diabetic retinopathy, according to the Fenofibrate ... OSN SuperSite

Sciele Pharma posts $13.8M profit  -  Oct 30, 2007
III clinical trials for both Glycopyrrolate and the Pravastatin/Fenofibrate combination," said Patrick Fourteau, president and CEO of Sciele Pharma. ... Bizjournals.com

Paradoxical Decrease in HDL-Cholesterol With Statin and Fenofibrate …  -  Mar 19, 2008
...[9,15] We present seven cases where HDL-C has been observed to be decreased during combination therapy with fenofibrate plus a statin. Medscape

GlobeNewswire, Inc. - News Room  -  Mar 24, 2005
Fenofibrate: Therapeutic doses of Fournier Pharma's main product fenofibrate ... The active ingredient in fenofibrate is fenofibric acid. ... primezone.com

Endorsing the Future Value of the Fenofibrate Franchise  -  May 7, 2006
Pharmaceutical groups AstraZeneca and Abbott today announced that they will jointly develop and commercialize in the United States a fixed-dose combination ... euronext.com

Lipofen™ (fenofibrate capsules), a New Prescription Treatment for …  -  Oct 3, 2007
By Staff. (HealthNewsDigest.com) - MONTGOMERY, AL, – ProEthic Pharmaceuticals, Inc. today announced that Lipofen™ (fenofibrate capsules), a new prescription ... HealthNewsDigest.com

Fenofibrate Slows Progression to Microalbuminuria in Diabetic Patients  -  Mar 29, 2005
Fenofibrate treatment for at least 3 years is effective in reducing the progression of renal disease in people with type 2 diabetes. ... Diabetes In Control

Atherogenesis; Lovastatin and fenofibrate have anti-inflammatory...  -  Jan 2, 2005
2005 JAN 2 - (NewsRx.com & NewsRx.net) -- Researchers have investigated C-reactive protein-induced expression of CD40-CD40L and the effect of lovastatin and ... Pay-Per-View - Heart Disease Weekly - Factiva, from Dow Jones

SCOLR Pharma, Inc. Starts CDT(R)-Fenofibrate Testing  -  Apr 9, 2007
SCOLR Pharma, Inc. (AMEX: DDD) announced today that it has commenced pilot bioavailability testing in Canada of its immediate release CDT(R)-fenofibrate ... Genetic Engineering News - Genetic Engineering News (press release)

… ; Cholesterol drug co-administered with fenofibrate study results...  -  Jan 27, 2005
The treatment with Zetia and fenofibrate for 12 weeks was also well-tolerated with a safety profile comparable to fenofibrate monotherapy. ... Pay-Per-View - Women's Health Weekly - Factiva, from Dow Jones

… ; Cholesterol drug co-administered with fenofibrate study results...  -  Jan 28, 2005
The treatment with Zetia and fenofibrate for 12 weeks was also well-tolerated with a safety profile comparable to fenofibrate monotherapy. ... Pay-Per-View - Drug Week - Factiva, from Dow Jones

… OF SHORT-TERM FENOFIBRATE TREATMENT ON CIRCULATING …  -  Feb 13, 2006
Context. Apart from lowering lipid levels, peroxisome proliferator-activated receptor (PPAR) activators (fibrates) produce many other favorable effects that ... Journal of Clinical Endocrinology and...

Fenofibrate Does Not Prevent Coronary Events  -  Apr 15, 2006
Synopsis: In this study, nearly 10000 patients between 50 and 75 years of age with type 2 diabetes were randomly assigned to receive 200 mg micronized ... AAFP News Now

… News: Fenofibrate may cut retinopathy in diabetes.(usage of fenofib...  -  Nov 10, 2007
Fenofibrate reduces the need for laser treatment of retinopathy in patients with type 2 diabetes, according to a controlled trial published early online by ... Free with registration - Chemist & Druggist - AccessMyLibrary.com

… ; Cholesterol drug co-administered with fenofibrate study results...  -  Jan 24, 2005
The treatment with Zetia and fenofibrate for 12 weeks was also well-tolerated with a safety profile comparable to fenofibrate monotherapy. ... Pay-Per-View - Health & Medicine Week - Factiva, from Dow Jones

… Therapy; PPAR alpha agonist fenofibrate improves diabetic nephropat...  -  Jun 27, 2006
The data revealed, "Fenofibrate treatment dramatically reduced fasting blood ... Fenofibrate also ameliorated insulin resistance (p<0.001) and reduced ... Pay-Per-View - Life Science Weekly - Factiva, from Dow Jones

SOY SAUCE ON BURN GIVES RELIEF  -  Aug 9, 2007
TriCor (fenofibrate) works differently from statins and Zetia. It can be an effective cholesterol-lowering drug that rarely causes muscle pain. ... Pay-Per-View - The Sun - ProQuest Archiver

… Trials; Type 2 diabetes trial shows fenofibrate can reduce...  -  Dec 20, 2005
2005 DEC 20 - (NewsRx.com) -- Results of the largest intervention study to assess the risk of cardiovascular disease events in people with type 2 diabetes ... Pay-Per-View - Life Science Weekly - Factiva, from Dow Jones

Hopes for Fenofibrate in diabetics dashed, primary end point unmet.( …  -  Jan 1, 2006
Hopes for Fenofibrate in diabetics dashed, primary end point unmet.(Metabolic Disorders) ... find Family Practice News articles. Pay-Per-View - Family Practice News - HighBeam Research

Combination of New Fenofibrate and Atorvastatin Improves Lipids in …  -  Apr 3, 2008
By Bruce Sylvester. CHICAGO -- April 3, 2008 -- Twelve weeks of daily combination treatment with the next-generation fenofibrate, ABT-335, and atorvastatin ... DG News

… Pharma A/S announces successful clinical trial of its novel fenofib...  -  Jan 5, 2005
Sales of Fenofibrate were in excess of $1 bn in 2004, and continue to demonstrate strong ... Fenofibrate is currently marketed by Abbott in the US under the ... Free with registration - Asia Africa Intelligence Wire - AccessMyLibrary.com

FDA Approves Triglide(TM) A Novel Formulation of Fenofibrate  -  May 10, 2005
SkyePharma PLC announces today that the US Food and Drug Administration ('FDA') has approved Triglide(TM), its novel formulation of fenofibrate. ... i-newswire.com

Lipid Research; Lipoprotein(a) level is increased by fenofibrate thera...  -  Mar 28, 2006
Fenofibrate therapy increased lipoprotein(a) level from 9.4±10.6 to 15.6 ±17.5 ... "Fenofibrate elevated lipoprotein(a) level greater in patients with a ... Pay-Per-View - Life Science Weekly - Factiva, from Dow Jones

Fenofibrate is Solvay Pharmaceuticals Flagship Product and Principal ...  -  Jan 12, 2007
Operating in the three sectors of Pharmaceuticals, Chemicals and Plastics, Solvay is represented worldwide. Over 95 per cent of its sales come from outside ... Free with registration - M2 Presswire - AccessMyLibrary.com

Novel therapy for lipid disorders shows mixed results in early...  -  Mar 25, 2007
In general, both LY518674 and fenofibrate were well tolerated, but the authors ... LY518674 and fenofibrate increased serum creatinine levels among patients ... eurekalert.org

… Announce Selection of Next-Generation Fenofibrate ABT-335 and …  -  Sep 2, 2007
ABT-335 is Abbott's next-generation fenofibrate currently in late-stage clinical trials. Based on the significant progress made in the ABT-335 and CRESTOR ... webwire.com

… burn victims' recovery, diabetes, metabolism aided by fenofibrate  -  Apr 25, 2005
..."We hoped that improving fat metabolism with fenofibrate, ... The patients were randomly assigned either to placebo or fenofibrate treatment after the first ... Pay-Per-View - Health & Medicine Week - Factiva, from Dow Jones

… burn victims' recovery, diabetes, metabolism aided by fenofibrate  -  Apr 30, 2005
..."We hoped that improving fat metabolism with fenofibrate, ... The patients were randomly assigned either to placebo or fenofibrate treatment after the first ... Pay-Per-View - Obesity, Fitness & Wellness Week - Factiva, from Dow Jones

… receives FDA approval for CIP-Fenofibrate. - PR Newswire |...  -  Jan 13, 2006
Cipher receives FDA approval for CIP-Fenofibrate. from PR Newswire. Highbeam Research – FREE Trial. Pay-Per-View - PR Newswire - HighBeam Research

Pharmaceuticals - Solvay Completes Fournier Pharma Buyout  -  Jul 12, 2005
Fenofibrate: Therapeutic doses of Fournier Pharma's main product fenofibrate ... The active ingredient in fenofibrate is fenofibric acid. ... Jobwerx

University of Liverpool; Fenofibrate lowers adiposity and corrects …  -  Mar 16, 2005
2005 MAR 16 - (NewsRx.com) -- Fenofibrate lowers adiposity and corrects metabolic abnormalities, but only partially restores endothelial function in dietary ... Pay-Per-View - Biotech Week - Factiva, from Dow Jones

Lowering triglycerides  -  Aug 6, 2005
If these actions aren't enough, then taking drugs such as fenofibrate (brand name Tricor) will lower triglyceride levels. Because of the increased risk of ... $2.95 - Buffalo News - NewsBank

Article: Fenofibrate curbed retinopathy in diabetic patients: need...  -  Dec 1, 2007
Fenofibrate curbed retinopathy in diabetic patients: need for laser therapy was cut by 37%.(Endocrinology)(Clinical report) ... find Internal Medicine News ... Pay-Per-View - Internal Medicine News - HighBeam Research

Fenofibrate cuts retinopathy in diabetic patients: those who were...  -  Dec 1, 2007
Fenofibrate cuts retinopathy in diabetic patients: those who were treated with the drug also had less progression of albuminuria and fewer amputations. Pay-Per-View - Family Practice News - HighBeam Research

Oscient Pharmaceuticals Reports Financial Results for First Quarter...  -  May 2, 2007
During this same period, prescriptions for branded fenofibrate products grew 2.3%. ... ANTARA([R]) (fenofibrate) capsules is indicated for the adjunct ... Free with registration - Business Wire - AccessMyLibrary.com

Daiichi Sankyo, Inc. Announces Filing Of Supplemental New Drug …  -  Jan 3, 2007
Additionally, WelChol has been studied with fenofibrate and had no significant ... WelChol, either alone or in combination with a statin or fenofibrate, ... Medical News Today - Medical News Today (press release)

Q2 2007 Oscient Pharmaceuticals Corporation Earnings Conference Call ...  -  Aug 2, 2007
Importantly, ANTARA growth and prescriptions again outpaced the branded fenofibrate market in total prescriptions. On the other hand, ... Free with registration - Fair Disclosure Wire - AccessMyLibrary.com

WelChol and Ezetimibe Combination Therapy Provides Significant LDL-C …  -  Nov 13, 2006
Additionally, WelChol has been studied with fenofibrate and had no effect on the ... WelChol, either alone or in combination with a statin or fenofibrate, ... RedOrbit

Sciele Enrolls Patients in Combination Pravastatin and Fenofibrate...  -  Oct 10, 2007
Sciele Pharma has completed enrollment of patients in a Phase III clinical trial using pravastatin and fenofibrate to treat mixed dyslipidemia. ... FDA news - FDA news (subscription)

Zetia, with fenofibrate, approved.(PRODUCTS)(Brief article)  -  Oct 15, 2006
Zetia (ezetimibe) has received an expanded approval in combination with diet and fenofibrate for the reduction of total cholesterol and ... Free with registration - Internal Medicine News - AccessMyLibrary.com

Sciele Pharma to test cholesterol drugs  -  Apr 18, 2007
The study will compare the combination of pravastatin and fenofibrate to pravastatin alone and fenofibrate alone. The phase III clinical trial will have 500 ... Atlanta Business Chronicle

Brand Names/Synonyms:
Fenofibrate is also known by the following brand names and/or synonymsAnkebin; Antara; CCRIS 7282; CHEMBANK1172; Elasterate; Elasterin; F6020; FNF; Fenobrate; Fenofibrate; Fenofibrate [Ban:Inn]; Fenofibrato [Inn-Spanish]; Fenofibratum [Inn-Latin]; Fenogal; Fenotard; Finofibrate; LF-178; Lipanthyl; Lipantil; Lipidex; Lipidil; Lipidil Micro; Lipidil Supra; Lipifen; Lipirex; Lipoclar; Lipofene; Liposit; Lipsin; Lofibra; Luxacor; Nolipax; Procetofen; Proctofene; Protolipan; Secalip; Sedufen; Tricor; Triglide

Drug Category:
Fenofibrate is categorized under the following by the FDA: Antilipemic Agents; Fribic Acid Derivatives; ATC:C10AB05

Dosage Forms:
CAPSULE; TABLET

Absorption:
Fenofibrate is well absorbed from the gastrointestinal tract. After absorption, fenofibrate is mainly excreted in the urine in the form of metabolites, primarily fenofibric acid and fenofibric acid glucuronide

Interactions:
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Chemical IUPAC Name:
1-methylethyl2-[4-(4-chlorobenzoyl)phenoxy]-2-methyl-propanoate





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