Fluconazole

This page contains recent news articles, when available, and an overview of Fluconazole but does not offer medical advice. You should contact your physician with regard to any health issues or concerns.


Overview:

Fluconazole
(when available)

Pharmacology and use:
Fluconazole, a synthetic antifungal agent of the imidazole class, is used to treat vaginal candidiasis. For the treatment of fungal infections.

Mechanism Of Action:
Fluconazole interacts with 14-α demethylase, a cytochrome P-450 enzyme necessary to convert lanosterol to ergosterol. As ergosterol is an essential component of the fungal cell membrane, inhibition of its synthesis results in increased cellular permeability causing leakage of cellular contents. Fluconazole may also inhibit endogenous respiration, interact with membrane phospholipids, inhibit the transformation of yeasts to mycelial forms, inhibit purine uptake, and impair triglyceride and/or phospholipid biosynthesis.

News Articles on Fluconazole

What Is Vaginitis? What Causes Vaginitis?  -  05 Jan 2010
Yeast infections may also be treated with an oral antifungal medication, such as fluconazole (Diflucan). The advantages of over-the-counter treatment for a ... Medical News Today

Conquering the Battle Zone in His Mind  -  ‎Dec 27, 2009‎
There was Trazodone, Gabapentin, Oxycodone, Citalopram, Fluconazole, Donepezil and Ranitidine — and, if the pharmaceutical combination did not drive him ... New York Times

Medicine en masse  -  ‎Dec 21, 2009‎
Add in their parents, plus other doctors/nurses coming in and out, asking if I had any spare Fluconazole or ear drops or if I could just have a quick look ... OnMedica

Cross-breeding leading to native livestock decline in Orissa  -  ‎Dec 13, 2009‎
Chlorpromazine, Ciprofloxacin, Co- amilozide, Diazepam, Dipyridamole, Erythromycin, Fluconazole, Fluoxetine, Indometacin, Ketoconozole, Lamotrigine, ... TopNews

Generic Name: Fluconazole, Trican  -  ‎Nov 11, 2009‎
Diflucan is different from other treatments for vaginal yeast infections because it is a tablet taken by mouth. Diflucan is also used to treat throat ... Pattaya Daily News

MethylGene Reports Third Quarter 2009 Financial Results  -  ‎Nov 5, 2009‎
Plans to initiate a 14-day study in combination with fluconazole are currently underway. This study is expected to commence by year-end. ... SYS-CON Media (press release)

MethylGene Reports Third Quarter 2009 Financial Results  -  ‎Nov 10, 2009‎
Plans to initiate a 14-day study in combination with fluconazole are currently underway. This study is expected to commence by year-end. ... PR-CANADA.net (press release)

The Medicinal Qualities of the Pumpkin  -  ‎Oct 29, 2009‎
Because C. albicans can become resistant to the antimycotics used to treat the infection, such as fluconazole, scientists hope this new discovery will lead ... eMaxHealth

MethylGene Inc. President and CEO, Donald F. Corcoran,  -  ‎Oct 21, 2009‎
...a fungal Hos2 inhibitor being developed for use in combination with fluconazole for serious fungal infections that is in Phase I clinical studies; ... TransWorldNews (press release)

المرأة الحامل..وسلامة تناول المضادات الحيوية  -  ‎Nov 12, 2009‎
Ù€ مجموعة من الأدوية المضادة للÙ?طريات أو الطÙ?يليات، مثل «Ù?لوكونازول» fluconazole و«ميكونازول» miconazole و«تيركونازول» terconazole و«ميبندازول» mebendazole. ... بلاغ

MethylGene présente ses résultats financiers du troisième trimestre de l ...  -  ‎Nov 5, 2009‎
La planification en vue de débuter une étude de 14 jours en traitement combiné avec du fluconazole est en cours. Cette étude devrait débuter d'ici la fin de ... Maketwire (Communiqué de presse)

Stevens-johnson syndrome  -  ‎Oct 23, 2009‎
...vcitane roznych liekov(wikipedia uvadza napr(allopurinol, diclofenac, etravirine, fluconazole,[2] valdecoxib, sitagliptin, oseltamivir, penicillins, ... Zdravie.sk

MethylGene émet des actions à Otsuka Pharmaceutical Co., Ltd.  -  ‎Oct 21, 2009‎
Le MGCD290, un inhibiteur d'Hos2 fongique en cours de développement en association avec du fluconazole pour traiter des infections fongiques, fait l'objet ... eMediaWorld.com Newswire Press Release Distribution Service (press release)

Fluconazole prophylaxis for prevention of invasive fungal infections...  -  Jan 10, 2008
Correspondence: Dr JH Weitkamp, Division of Neonatology, Department of Pediatrics, Monroe Carell Jr Children's Hospital at Vanderbilt, 1125 MRB IV/Light ... Nature.com

Aurobindo Pharma gets US FDA nod for Fluconazole tablets  -  Oct 13, 2008
PTI. Mumbai: Aurobindo Pharma today said it has received US regulatory approval for manufacturing and marketing of Fluconazole tablets, ... Livemint

JB Chem receives US FDA nod for fluconazole tablets  -  Sep 30, 2005
PTI / Mumbai September 30, 2005. JB Chemicals & Pharmaceuticals said on Thursday that it had received an approval from the US Food and Drug Administration ... Business Standard

Study: New Pfizer Drug No Better Than Old  -  Jun 14, 2007
Although prices of Eraxis and similar brand-name antifungals have "dropped substantially," they remain "several-fold higher than that of generic fluconazole ... TheStreet.com - TheStreet.com (subscription)

Fluconazole prophylaxis in extremely low birth weight infants:...  -  Feb 20, 2006
Correspondence: Dr ZH Aghai, Department of Pediatrics/Neonatology, Cooper University Hospital-UMDNJ, 755 Dorrance Bldg, One Cooper Plaza, Camden, NJ 08103, ... Nature.com

Schering drug prevents fungus in patients: study  -  Jan 24, 2007
That compares to 8 percent among the volunteers receiving either of two drugs available in generic form, fluconazole or itraconazole. ... Reuters

… with cranberry juice, grape juice, tea, and fluconazole: In vitro...  -  Jul 7, 2005
However, clearance in the fluconazole treatment condition (trial 5) was significantly reduced compared with the placebo control (175 mL/min versus 318 ... Nature.com

Pfizer's Anti-Fungal Treatment Approved  -  Feb 21, 2006
...“In the clinical trial setting, patients taking Eraxis for the treatment of candidemia had improved efficacy versus those taking fluconazole, making Eraxis ... Forbes

Anidulafungin (Eraxis) As Effective As Fluconazole (Diflucan)  -  Jun 14, 2007
By Michael Smith, Senior Staff Writer, MedPage Today. CAMDEN, NJ, June 14 -- In a head-to-head trial, anidulafungin (Eraxis) was at least as effective in ... MedPage Today

… FDA clearance for first automated fluconazole MIC Susceptibility...  -  Sep 27, 2006
The fluconazole susceptibility tests will be used to determine the ... The Fluconazole Minimum Inhibitory Concentration (MIC) Susceptibility test card for ... carolinanewswire.com

Aurobindo Pharma gets USFDA nod for two drugs  -  Oct 10, 2008
Fluconazole Tablets are used to treat fungal infection. Cyclobenzaprine is a generic version of MCNEIL -PPC's Flexeril tablets and are indicated to be used ... The Hindu

Spectrum receives FDA approval for fluconazole tablets  -  Oct 1, 2005
Spectrum Pharmaceuticals Inc. has received an approval from the office of generic drugs of the US Food and Drug Administration for the abbreviated new drug ... pharmabiz.com

Learn about Fluconazole from Consumer Reports Health.  -  Jan 4, 2005
Fluconazole is used to treat fungal infections, including yeast infections of the vagina, mouth, throat, esophagus (tube leading from the mouth to the ... consumerreports.org

Empirical Fluconazole Versus Placebo For Intensive Care Unit Patients  -  Aug 22, 2008
This study confirms two previous meta-analyses that showed that fluconazole is ineffective in decreasing mortality in general high-risk ICU patients. ... Medscape

Oral fixed drug eruption due to fluconazole.(Letter To Editor)( …  -  Sep 1, 2006
We report a case of oral FDE caused by fluconazole - a triazole antifungal agent. ... The patient had been prescribed oral fluconazole 150 mg weekly along ... Free with registration - Indian Journal of Dermatology, Venereolo... - AccessMyLibrary.com

In re Vicuron Pharmaceuticals, Inc. Securities Litigation, No. 04...  -  May 31, 2007
...fn1 At that time the two favored drugs for the treatment of EC were fluconazole and Caspofungin and Vicuron believed anidulafungin would join or surpass ... $2.95 - U.S. District Court, Eastern District... - VersusLaw

Teva Announces Approval of Fluconazole Injection.  -  Jan 14, 2005
JERUSALEM -- Teva Pharmaceutical Industries Ltd. (Nasdaq:TEVA) announced today that the US Food and Drug Administration has granted final approval of the ... Free with registration - Business Wire - AccessMyLibrary.com

Noxafil(R) (Posaconazole) Oral Suspension Approved in European Union …  -  Nov 9, 2006
A reduction in proven and probable IFIs vs. fluconazole/itraconazole [7/304 (2%) vs. ... A safety and tolerability profile comparable to fluconazole. ... DG News

Fluconazole prophylaxis: resistance risk lower than fungal disease...  -  Nov 10, 2005
Long-term prophylaxis against fungal infections using fluconazole may prove cost-effective in countries with a high burden of fungal diseases among people ... Aidsmap

MethylGene Presents Preclinical Data for MGD290, a Hos2 Fungal …  -  Oct 27, 2008
In this preclinical study, immunocompromised CD-1 mice were inoculated intravenously with a fluconazole-resistant clinical isolate of Candida albicans. ... International Business Times

Prophylactic Fluconazole May Reduce Candida Infection in Preterm …  -  Jun 18, 2007
June 18, 2007 -- Prophylactic fluconazole reduces the incidence of colonization and candida infection in preterm neonates, according to the results of a ... Medscape

… successful in treating fluconazole- and itraconazole-resistant...  -  Feb 15, 2007
An open-label study of oral posaconazole has found that it safely and effectively treats oropharyngeal and oesophageal candidiasis in people resistant to ... Aidsmap

Teva gets FDA OK for fluconazole injection.(Teva Pharmaceutical …  -  Jan 24, 2005
Isreal's Teva Pharmaceutical Industries says that the US Food and Drug Administration has granted final approval of its Abbreviated New Drug Application for ... $4.95 - Pharma Marketletter - ECNext

Free HIV drug for Aids patients  -  Feb 28, 2008
Free anti-fungal tablets known as Fluconazole are available and people who are infected ... Fluconazole, whose trade name is Diflucan is manufactured and ... Daily Monitor

Taking Fluconazole Injection from Consumer Reports Health.  -  Jan 8, 2006
Fluconazole may cause side effects. Tell your health care provider if any of these symptoms are severe or do not go away: ... consumerreports.org

The New England Journal Of Medicine Publishes Two Landmark Studies …  -  Jan 25, 2007
Fluconazole or Itraconazole Prophylaxis in Patients with Neutropenia (Cornely et ... In this study, NOXAFIL versus fluconazole/itraconazole demonstrated a ... Free with registration - PR Newswire - AccessMyLibrary.com

Low-dose fluconazole may prevent invasive fungal infection in...  -  Jan 1, 2005
SAN FRANCISCO -- Fluconazole prophylaxis twice weekly during the first 6 weeks of life is similar to the previously studied schedule of more frequent doses ... Free with registration - Pediatric News - AccessMyLibrary.com

Antiadrenal Ketoconazole Antifungal, systemic Fluconazole Itraconazole...  -  Aug 1, 2006
Cisapride (eg, Propulsid) -- Cisapride should not be taken with fluconazole, itraconazole or oral ketoconazole; these azole antifungals may increase the ... Free with registration - USP DI-Volume II, Advice for the... - AccessMyLibrary.com

Does posaconazole prevent invasive fungal infections in patients with...  -  May 18, 2007
...(2007) Posaconazole vs. fluconazole or itraconazole prophylaxis in patients with ... Fewer patients in the posaconazole group than in the fluconazole or ... Nature.com

Generic Drugs; US FDA grants approval ANDA for anti-fungal fluconazole...  -  Oct 29, 2005
Fluconazole is a widely used anti-fungal agent. ... The ANDA for fluconazole is the second oral product filed by NeoJB, LLC, a joint venture between ... Pay-Per-View - Obesity, Fitness & Wellness Week - Factiva, from Dow Jones

Fluconazole in NICU not linked to resistance.(Infectious Diseases)( …  -  Jan 15, 2007
TORONTO -- Fluconazole prophylaxis for invasive candidiasis in extremely low-birth-weight infants is not associated with the emergence of ... Free with registration - Family Practice News - AccessMyLibrary.com

USA pharma: Aurobindo receives FDA nod for fluconazole  -  Oct 15, 2008
Aurobindo Pharma today said it has received US regulatory approval for manufacturing and marketing of Fluconazole tablets, used as an anti-fungal drug. ... $34.00 - EIU Country Analysis - Alacra Store

… , Inc. US FDA grants approval ANDA for anti-fungal fluconazole table...  -  Oct 26, 2005
Fluconazole is a widely used anti-fungal agent. ... The ANDA for fluconazole is the second oral product filed by NeoJB, LLC, a joint venture between ... Pay-Per-View - Biotech Week - Factiva, from Dow Jones

Noxafil wins approval for the prevention of invasive Aspergillus,...  -  Nov 1, 2006
After 100 days, these figures were 5% for the posaconazole group and 11% for the fluconazole/itraconazole group. Reported side effects of posaconazole ... Free with registration - Internal Medicine News - AccessMyLibrary.com

Boric Acid Beats Fluconazole for Candidiasis in Diabetics  -  Feb 20, 2007
Boric acid vaginal suppositories appear to be more effective than oral fluconazole in the treatment of diabetics with non-albicans Candida glabrata ... Diabetes In Control

Spectrum Pharmaceuticals Receives FDA Approval for Fluconazole …  -  Sep 28, 2005
Fluconazole is a widely used anti-fungal agent. ... The ANDA for fluconazole is the second oral product filed by NeoJB, LLC, a joint venture between ... $4.95 - PR Newswire - ECNext

Voriconazole: A highly potent treatment for fungal infections  -  Dec 16, 2008
The researchers analyzed the effect of itraconazole, fluconazole, amphotericin B ... It is notably more active than fluconazole in terms of both potency and ... eurekalert.org

Article: Fluconazole prophylaxis in NICU not linked to resistance.(ID...  -  Dec 1, 2006
TORONTO -- Fluconazole prophylaxis for invasive candidiasis in extremely low-birth-weight infants is not associated with the emergence of ... Pay-Per-View - Pediatric News - HighBeam Research

Generic Drugs; US FDA grants approval ANDA for anti-fungal fluconazole...  -  Oct 24, 2005
Fluconazole is a widely used anti-fungal agent. ... The ANDA for fluconazole is the second oral product filed by NeoJB, LLC, a joint venture between ... Pay-Per-View - Anti-Infectives Week - Factiva, from Dow Jones

Polk Jail Couey Trial Nurse Continue Faces  -  Feb 15, 2007
When detectives interviewed her and searched her home, they found several types of prescription drugs, including amoxicillin and fluconazole. ... Lakeland Ledger - Google News Archive

New drugs could slow rise in fungal infections.(Dermatologic Therapy)  -  Nov 1, 2006
Moreover, mainstay drugs like fluconazole, itraconazole, ketoconazole, terbinaline, and griseofulvin are more widely used than ever, applying plenty of ... Free with registration - Skin & Allergy News - AccessMyLibrary.com

Sumatriptan, fluconazole called safe too.(News)  -  Dec 15, 2005
Sumatriptan and fluconazole were among the drugs that received a green light for routine adverse event monitoring by the Food and Drug Administration's ... Pay-Per-View - Family Practice News - Factiva, from Dow Jones

Pronunciation : (floo koe' na zole)  -  Apr 27, 2008
Fluconazole also has been used to treat vaginal infections. When it is to be taken : Fluconazole is usually taken once a day. Follow the instructions on ... MedIndia

… with invasive candidiasis.(echinocandin anidulafungin and fluconazo...  -  Sep 1, 2007
Additional encouraging findings have recently been reported by Reboli and coworkers, who compared anidulafungin with fluconazole in a randomized, ... $4.95 - Journal of Respiratory Diseases - ECNext

New Study Shows NOXAFIL(R) (Posaconazole) Oral Suspension …  -  Oct 25, 2005
In the study, NOXAFIL compared to fluconazole significantly reduced the ... 21; p=.006) compared to fluconazole and was as effective as fluconazole in ... RedOrbit

Article: Sumatriptan, fluconazole also called safe.(News) - Skin &...  -  Jan 1, 2006
Sumatriptan, fluconazole also called safe.(News) ... find Skin & Allergy News articles. Sumatriptan and fluconazole were among the drugs that received a ... Pay-Per-View - Skin & Allergy News - HighBeam Research

How Reducing Yeast in your Diet can Cure Candida ?  -  Mar 12, 2008
...and other symptoms of yeast overgrowth receive medical treatment in the form of products like Difflucan, Fluconazole or over the counter medications. ... Buzzle

OTC: In brief - Vantage fluconazole.(Brief article)  -  Sep 30, 2006
New in the Vantage own-label range are fluconazole 150mg single-dose capsules to provide relief from thrush symptoms. Vantage Fluconazole retails at #4.99. $4.95 - Chemist & Druggist - ECNext

Effect of fluconazole on phagocytic response of polymorphonuclear …  -  Jan 1, 2005
Recently, fluconazole (FLZ) has been shown to improve survival and reduce multiorgan ... Fluconazole (FLZ) is a well-tolerated antifungal drug with a ... Free with registration - Mediators of Inflammation - AccessMyLibrary.com

Fluconazole in NICU not linked to resistance.(Infectious Diseases)( …  -  Jan 15, 2007
Fluconazole in NICU not linked to resistance.(Infectious Diseases)(neonatal intensive care unit) ... find Family Practice News articles. Pay-Per-View - Family Practice News - HighBeam Research

Literature Commentary by Dr. Bartlett: Cryptococcal Meningitis, Jan...  -  Jan 15, 2008
Patients with a baseline GCS < 10 received oral fluconazole (400 mg/d) for 10 weeks. Beginning at week 10, the fluconazole dose was changed to 200 mg/d for ... Medscape

National Pharmacy Association concerns.(fluconazole 150mg capsules …  -  Nov 10, 2005
The National Pharmacy Association says it has &quot;serious concerns&quot; about the request to reclassify fluconazole 150mg capsules from P to GSL for the ... $4.95 - Community Pharmacy - ECNext

Article: Fluconazole reduces candidiasis in VLBW infants.(Infectious ...  -  Oct 1, 2006
SAN FRANCISCO -- Fluconazoleprophylaxis reduced fungal infections and mortality in very low-birth-weight infants at two neonatal intensive care units in ... Pay-Per-View - Pediatric News - HighBeam Research

TNF-[alpha] inhibitors may raise coccidioidomycosis risk.(Clinical...  -  May 1, 2007
All but one patient were treated with fluconazole 200 mg twice daffy (orally for ... It may be safe if patients continue fluconazole and as long as their ... Free with registration - Skin & Allergy News - AccessMyLibrary.com

FDA Fast Track Designation for Basilea's Novel Broad-Spectrum Water- …  -  May 2, 2006
BAL8557's extended antifungal spectrum covers most yeasts and molds including fluconazole resistant candida strains, aspergillus and zygomyces that cause ... primezone.com

Fluconazole; Bioequivalence of fluconazole capsules evaluated  -  Apr 10, 2005
According to published research from Brazil, "Fluconazole is an antifungal agent. The purpose of this study was to evaluate bioequivalence of two commercial ... Pay-Per-View - Medical Letter on the CDC & FDA - Factiva, from Dow Jones

Fluconazole; Bioequivalence of fluconazole capsules evaluated  -  Apr 4, 2005
According to published research from Brazil, "Fluconazole is an antifungal agent. The purpose of this study was to evaluate bioequivalence of two commercial ... Pay-Per-View - Clinical Trials Week - Factiva, from Dow Jones

Basilea Maintains Global Commercialization Rights for BAL8557, its …  -  Dec 19, 2005
The phase II study compared three dosing regimens of BAL8557 to fluconazole in the treatment of esophageal candidiasis to demonstrate antifungal efficacy in ... Free with registration - Europe Intelligence Wire - AccessMyLibrary.com

Anti-fungal drug fomeningitis in HIV-positive patients  -  Oct 26, 2008
It aimed at assessing whether routine use of fluconazole, can prevent cryptococcal ... Half of these were put on fluconazole capsules and others on placebo ... New Vision

Vicuron reports positive Phase III results.(Tuesday, February...  -  Feb 14, 2005
Vicuron Pharmaceuticals Inc. said data from a Phase III trial of its antifungal product anidulafungin demonstrated superior results compared to fluconazole ... Free with registration - BioWorld Week - AccessMyLibrary.com

Glancy Binkow & Goldberg LLP, Representing Investors Who Purchased …  -  Nov 15, 2005
The next day, based on the huge disparity between defendants' prior guidance and the realization that Hyphanox failed to work as well as fluconazole, ... primezone.com

Letter: Fluconazole switch concerns.(Letter to the Editor)  -  Oct 15, 2005
I am dismayed to learn that yet another company has applied for an inappropriate P to GSL reclassification. I'm referring to Relonchem's proposal to ask the ... $4.95 - Chemist & Druggist - ECNext

Schatz & Nobel, PC Announces Class Action Lawsuit Against Barrier …  -  Oct 11, 2005
...did not have a better safety or efficacy profile than fluconazole/Diflucan and, ... Hyphanox was significantly less effective than fluconazole/Diflucan; ... primezone.com

Azoles for ringworm of the scalp or beard  -  Apr 24, 2007
Fluconazole seems to work just as well as griseofulvin to treat ringworm of the scalp. But fluconazole has not been used for as many years as griseofulvin. ... MSN Health & Fitness

IN BRIEF: Fluconazole switch?  -  Sep 24, 2005
IN BRIEF: Fluconazole switch? Pharmaceutical company Relonchem Ltd has applied for a Pharmacy (P) to General Sales List (GSL) switch for its vaginal thrush ... $9.94 - Chemist & Druggist - Alacra Store

… Receives FDA Approval for Fluconazole Tablets. - PR Newswire | …  -  Sep 28, 2005
Spectrum Pharmaceuticals Receives FDA Approval for Fluconazole Tablets. from PR Newswire. Highbeam Research – FREE Trial. Pay-Per-View - PR Newswire - HighBeam Research

Letter: Fluconazole switch concerns  -  Oct 15, 2005
I am dismayed to learn that yet another company has applied for an inappropriate P to GSL reclassification. I'm referring to Relonchem's proposal to ask the ... Pay-Per-View - Chemist & Druggist - Factiva, from Dow Jones

Sumatriptan, fluconazole called safe too.(News) | Article from Family...  -  Dec 15, 2005
Sumatriptan, fluconazole called safe too.(News) ... find Family Practice News articles. Sumatriptan and fluconazole were among the drugs that received a ... Pay-Per-View - Family Practice News - HighBeam Research

Micafungin (Mycamine[trademark])  -  Dec 1, 2005
However, fluconazole is not effective against certain non-albicans species, including C. krusei and C. glabrata and is, therefore, not recommended for the ... Free with registration - Infectious Disease Alert - AccessMyLibrary.com

… Site Release[R] vaginal cream (Gynazole-1[R]) compared to fluconazo...  -  Jan 1, 2005
Fluconazole (Diflucan[R]) is the only orally available imidazole with approved ... Several clinical studies have compared a single fluconazole 150 mg oral ... Free with registration - Infectious Diseases in Obstetrics and... - AccessMyLibrary.com

… switch.(Bayer HealthCare expressed concerns to switch fluconazole)(...  -  Oct 15, 2005
Bayer Healthcare has expressed concerns over Relonchem's recent application to switch fluconazole 150mg capsules from P to GSL status (C&D, September 24, ... $4.95 - Chemist & Druggist - ECNext

Medicalmatters: Single dose fluconazole leads to bleeds.(Brief...  -  Mar 11, 2006
Single dose fluconazole may increase the risk of bleeding in warfarin patients, a US study has warned. Emerging findings have highlighted the risk posed by ... $4.95 - Chemist & Druggist - ECNext

65 -- FLUCONAZOLE ORAL TABLETS  -  Aug 15, 2005
CLASSIFICATION CODE: 65 - Medical, dental & veterinary equipment & supplies SUBJECT: 65 -- Fluconazole Oral Tablets SOLICITATION NUMBER: 797-NC-05-0043 ... Pay-Per-View - FedBizOpps - Factiva, from Dow Jones

65 -- FLUCONAZOLE ORAL TABLETS  -  Aug 15, 2005
CLASSIFICATION CODE: 65 - Medical, dental & veterinary equipment & supplies SUBJECT: 65 -- Fluconazole Oral Tablets SOLICITATION NUMBER: 797-NC-05-0043 ... Pay-Per-View - FedBizOpps - Factiva, from Dow Jones

Fluconazole switch concern.(Brief Article)  -  Oct 22, 2005
Serious safety concerns have prompted the NPA to oppose the recent proposal to reclassify as GSL fluconazole 150mg capsules for treating vaginal candidiasis ... $4.95 - Chemist & Druggist - ECNext

Nail Fungus Products – Are they worthy?  -  Sep 29, 2006
Oral treatment include the use of Itraconazole (Sporanox), Fluconazole (Diflucan) or Terminafine (Lamisil). Of course if you prefer to go the natural way, ... Buzzle

Vicuron Pharmaceuticals Announces Phase 3 Trial Results Demonstrate …  -  Feb 7, 2005
The study compared anidulafungin to fluconazole, and was designed to show ... Anidulafungin was superior to fluconazole in the primary endpoint, ... RedOrbit

New treatment for oral thrush as effective as current standard of...  -  Mar 29, 2006
The current standards of care are fluconazole or itraconazole, ... The impact of posaconazole and fluconazole on candida cultured from patients enrolled in ... Aidsmap

Systemic Antifungal Therapy for Cutaneous Infections in Children  -  Jul 24, 2006
Patients were randomly assigned to one of 3 fluconazole dosage regimens (1.5, ... Systemic therapy with fluconazole 6 mg/kg/d and griseofulvin 11 mg/kg/d ... Medscape

Generic Drugs; Pharmaceutical company receives US FDA approval for …  -  Feb 14, 2005
Fluconazole is the generic equivalent of Pfizer's antifungal agent Diflucan. Total annual sales of this configuration of fluconazole injection, ... Pay-Per-View - Pharma Business Week - Factiva, from Dow Jones

Generic Drugs; Pharmaceutical company receives US FDA approval for …  -  Feb 15, 2005
Fluconazole is the generic equivalent of Pfizer's antifungal agent Diflucan. Total annual sales of this configuration of fluconazole injection, ... Pay-Per-View - Science Letter - Factiva, from Dow Jones

Pfizer to buy biotech Vicuron in $1.9B deal to gain anti-infective...  -  Jun 27, 2005
Recently, Vicuron announced positive Phase III results on anidulafungin, demonstrating superiority versus fluconazole in invasive candidiasis/candidemia. ... $4.95 - Pharma Marketletter - ECNext

Fighting fungal infections: new antifungal therapies may help tame...  -  Aug 7, 2006
In vitro and in vivo studies show that posaconazole has activity against Candida species, including fluconazole-resistant non-albicans strains, ... Free with registration - Drug Topics - AccessMyLibrary.com

Preventing invasive fungal infections: Results of two studies on …  -  Apr 1, 2007
The first study compared posaconazole with fluconazole in patients with graft versus host disease. The second compared it with fluconazole or itraconazole ... $4.95 - Journal of Respiratory Diseases - ECNext

Posaconazole demonstrates efficacy for prophylaxis of fungal infection...  -  Mar 1, 2007
Posaconazole demonstrated efficacy equal to fluconazole (with a trend ... Posaconazole or fluconazole for prophylaxis in severe graft-versus-host disease. ... $9.94 - Formulary - Alacra Store

Pfizer's Vfend equals two-drug candidemia regimen, with fewer serious...  -  Nov 7, 2005
In addition, the prevalence of fluconazole-resistant Candida is increasing. The study used a non-inferiority study design in which the trial objective was ... Medical News Today - Medical News Today (press release)

Lancet study: Pfizer's Vfend equals two-drug candidemia regimen, with...  -  Nov 4, 2005
In addition, the prevalence of fluconazole-resistant Candida is increasing. The study used a non-inferiority study design in which the trial objective was ... eurekalert.org

HOW SHOULD WE USE ANTI-FUNGALS TO TREAT THRUSH?  -  Oct 22, 2005
Treatment was with a single 150mg oral dose of fluconazole or placebo tablet ... With weekly oral fluconazole, only one in 10 women had a recurrence of ... Free with registration - Pulse - AccessMyLibrary.com

Anidulafungin Appears Safe in Patients With Candidiasis: Presented at...  -  Oct 14, 2005
Fluconazole was dose-adjusted for creatinine clearance. ... Dr. Rotstein said that fluconazole is currently the standard of care for Candida and that ... DG News

FDA Approves Noxafil(R) (Posaconazole) for Prevention of Invasive …  -  Sep 18, 2006
A reduction in proven and probable IFIs vs. fluconazole/itraconazole (2% vs. ... A reduction in proven/probable IFIs at 16 weeks compared to fluconazole (5% ... DG News

Schering-Plough Announces FDA Approval Of NOXAFIL(R) ( …  -  Sep 19, 2006
A reduction in proven and probable IFIs vs. fluconazole/itraconazole (2 ... A reduction in proven/probable IFIs at 16 weeks compared to fluconazole (5 ... Medical News Today - Medical News Today (press release)

Prophylaxis or treatment in coping with invasive fungal infections;...  -  Apr 24, 2006
Conventional therapy for IFI includes fluconazole, itraconazole and ... "Fluconazole and micafungin lack mould activity and fluconazole has been associated ... Pay-Per-View - Pharma Marketletter - Factiva, from Dow Jones

A review of the new antifungals: posaconazole, micafungin, and …  -  Dec 1, 2007
Posaconazole is a triazole in the same class as fluconazole. ... Anidulafungin was shown to be noninferior to fluconazole in the treatment of invasive ... $4.95 - Journal of Drugs in Dermatology - ECNext

Cutaneous sporotrichosis of face: Polymorphism and reactivation after...  -  May 1, 2007
SSKI was stopped and fluconazole (600 mg/day) was started. Lesional erythema, tenderness and pus discharge subsided in five days. SSKI was reintroduced at a ... Free with registration - Indian Journal of Dermatology, Venereolo... - AccessMyLibrary.com

Antifungal Therapy; US FDA approves Schering-Plough's posaconazole …  -  Oct 18, 2006
An open-label study compared Noxafil oral suspension 200 mg three times daily (n=304) to pooled standard azole therapies (fluconazole oral suspension 400 mg ... Pay-Per-View - Biotech Week - Factiva, from Dow Jones

Antifungal Therapy; US FDA approves Schering-Plough's posaconazole …  -  Oct 20, 2006
An open-label study compared Noxafil oral suspension 200 mg three times daily (n=304) to pooled standard azole therapies (fluconazole oral suspension 400 mg ... Pay-Per-View - Drug Week - Factiva, from Dow Jones

Press Release: Vicuron Pharmaceuticals Announces Phase 3 Trial …  -  Feb 7, 2005
The study compared anidulafungin to fluconazole, and was designed to show ... Anidulafungin was superior to fluconazole in the primary endpoint, ... Pay-Per-View - PR Newswire - HighBeam Research

An Emerging Extended-Spectrum Triazole Antifungal: Noxafil[R] ( …  -  Jun 1, 2006
Posaconazole vs Fluconazole for Prophylaxis of Invasive Fungal Infections in Allogeneic Hematopoietic Stem Cell Transplant Recipients with Graft-versus-Host ... Free with registration - Infectious Disease Alert - AccessMyLibrary.com

Breakthrough fungal infections after allogeneic hematopoietic stem...  -  Jun 25, 2007
2 Current evidence-based guidelines recommend 400 mg fluconazole daily after HSCT ... However, fluconazole has no activity against Aspergillus or the more ... Nature.com

Empirical Anti-Candida Therapy among Selected Patients in the...  -  Dec 20, 2005
Empirical fluconazole therapy is the most reasonable strategy ($12 593 per DLY ... For low prevalences of invasive candidiasis, culture-based fluconazole is ... Annals of Internal Medicine

Brand Names/Synonyms:
Fluconazole is also known by the following brand names and/or synonymsBiocanol; Biozolene; Diflucan; Diflucan in Sodium Chloride 0.9%; Elazor; FLUCONAZOLE , 99%; Flucazol; Fluconazole; Fluconazole in Sodium Chloride 0.9%; Flucostat; Flukezol; Flunizol; Flusol; Pritenzol; Triflucan

Drug Category:
Fluconazole is categorized under the following by the FDA: Antifungals; Antifungals; ATC:D01AC15; ATC:J02AC01

Dosage Forms:
CAPSULE; LIQUID; POWDER FOR SOLUTION; SOLUTION; TABLET

Absorption:
90%

Interactions:
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Chemical IUPAC Name:
2-(2,4-difluorophenyl)-1,3-bis(1H-1,2,4-triazol-1-yl)propan-2-ol





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