Fluphenazine Decanoate

This page contains recent news articles, when available, and an overview of Fluphenazine Decanoate but does not offer medical advice. You should contact your physician with regard to any health issues or concerns.


Overview:

Fluphenazine Decanoate
(when available)

Pharmacology and use:
Fluphenazine is a trifluoro-methyl phenothiazine derivative intended for the management of schizophrenia and other psychotic disorders. Fluphenazine has not been shown effective in the management of behaviorial complications in patients with mental retardation. For management of manifestations of psychotic disorders.

Mechanism Of Action:
Fluphenazine blocks postsynaptic mesolimbic dopaminergic D1 and D2 receptors in the brain; depresses the release of hypothalamic and hypophyseal hormones and is believed to depress the reticular activating system thus affecting basal metabolism, body temperature, wakefulness, vasomotor tone, and emesis.

News Articles on Fluphenazine

Historical perspective on antipsychotic long-acting injections  -  ‎Oct 31, 2009‎
Two years later, fluphenazine decanoate was introduced as a 3-weekly injection. The next available preparation, flupenthixol decanoate, was also recommended ... British Journal of Psychiatry

Fluphenazine decanoate for psoriasis.(PSORIASIS)(Brief article)  -  Oct 1, 2007
Condition Intervention Phase Psoriasis Drug: Fluphenazine Decanoate Phase II Study ID Numbers: FP-CL1 ClinicalTrials.gov Identifier: NCT00356200. Free with registration - Journal of Drugs in Dermatology - AccessMyLibrary.com

Haloperidol decanoate v. fluphenazine decanoate as maintenance …  -  Mar 1, 2005
In a double-blind study of 38 chronic schizophrenic in-patients, haloperidol decanoate was compared with fluphenazine decanoate as maintenance therapy over ... British Journal of Psychiatry (subscript...

Fluphenazine decanoate for psoriasis.(PSORIASIS)(Brief article)  -  Oct 1, 2007
Sponsors and Collaborators: Tufts-New England Medical Center and Immune Control. The purpose of this research study is to evaluate the effectiveness and ... $4.95 - Journal of Drugs in Dermatology - ECNext

… the Dose Regime of Fluphenazine Decanoate in Maintenance Therapy...  -  Mar 1, 2005
An analysis of the drug regimes prescribed to two separate groups of unselected schizophrenic. patients indicates certain trends of clinical importance. ... British Journal of Psychiatry (subscript...

… Code - 77 Ill. Adm. Code 790.3996 FLUPHENAZINE DECANOATE ( …  -  Aug 10, 2005
77 Ill. Adm. Code 790.3996 FLUPHENAZINE DECANOATE (Repealed) Repealed. (Source: Repealed at 17 Ill. Reg. 15916, effective September 20, 1993) ... Pay-Per-View - Illinois Administrative Code - Loislaw

The conventional long-acting antipsychotics.(RX Primer)  -  Mar 22, 2006
Fluphenazine decanoate is available for both intramuscular and ... Both haloperidol decanoate and fluphenazine decanoate can cause the following adverse ... $4.95 - Annals of the American Psychotherapy... - ECNext

The conventional long-acting antipsychotics.(RX Primer) | Article...  -  Mar 22, 2006
Fluphenazine decanoate is available for both intramuscular and ... Both haloperidol decanoate and fluphenazine decanoate can cause the following adverse ... Pay-Per-View - Annals of the American Psychotherapy... - HighBeam Research

Adverse Effects of a Performance Enhancer  -  Sep 27, 2006
Researchers noted that the side effects of fluphenazine decanoate appear to be "unpredictable and can be severe and life threatening. ... TheHorse.com

Antipsychotics' effects differ in substance abusers: activation of …  -  Jun 1, 2005
...haloperidol decanoate (Haldol), and fluphenazine decanoate. This enzyme does not metabolize risperidone or ziprasidone, said Dr. Stuyt of the University ... Pay-Per-View - Clinical Psychiatry News - Factiva, from Dow Jones

The depot paradox: long-acting formulations of antipsychotics can...  -  May 1, 2007
I am reminded of a study I conducted 20 years ago, in which I measured the pharmacokinetic profile of fluphenazine decanoate in outpatients. (12) For this. $4.95 - Behavioral Healthcare - ECNext

Lillys Zyprexa LAI trips up over sedation effects  -  Mar 3, 2008
...haloperidol decanoate and fluphenazine decanoate; and one atypical, risperidone long-acting injection (Johnson & Johnson's Risperdal Consta). ... In-PharmaTechnologist.com

United States v. Session, No. 04-783-01 (EDPa. 08/14/2006)  -  Aug 14, 2006
...including an intramuscular injection of an anti-psychotic drug (fluphenazine decanoate) on a bi-monthly basis, removed Session's "overt" psychotic ... $2.95 - U.S. District Court, Eastern District... - VersusLaw

Psychiatric Times. Coffee, Cigarettes and Meds: What Are the Metabolic...  -  May 1, 2005
Fluphenazine (Permitil, Prolixin) clearance is increased significantly in smokers, and lower levels of fluphenazine decanoate have been reported (Jann et ... Psychiatric Times

WHO expert committee on specifications for pharmaceutical preparations...  -  Aug 1, 2005
200mg 195199 9930312 fluorouracil 100mg 184122 9930313 fluphenazine decanoate dihydrochloride 100mg 182107 9930314 fluphenazine enantate dihydrochloride ... Free with registration - Technical Report Series - AccessMyLibrary.com

Loislaw Federal District Court Opinions - US v. SESSION (EDPa. 8-14- …  -  Aug 14, 2006
...including an intramuscular injection of an anti-psychotic drug (fluphenazine decanoate) on a bi-monthly basis, removed Session's "overt" psychotic ... Pay-Per-View - Loislaw Federal District Court Opinions - Loislaw

Antipsychotics' effects differ in substance abusers: activation of …  -  Jun 1, 2005
...haloperidol decanoate (Haldol), and fluphenazine decanoate. This enzyme does not metabolize risperidone or ziprasidone, said Dr. Stuyt of the University ... Pay-Per-View - Clinical Psychiatry News - HighBeam Research

Article: Schizophrenia prodrome therapies show promise: early …  -  Oct 1, 2005
...an outpatient research clinic at UCLA from 1981 to 1992, patients were treated with fluphenazine decanoate, usually in a dose of 12.5 mg every 2 weeks . ... Pay-Per-View - Clinical Psychiatry News - HighBeam Research

Brand Names/Synonyms:
Fluphenazine Decanoate is also known by the following brand names and/or synonymsAnatensol; Apo-Fluphenazine; Elinol; Fluorfenazine; Fluorophenazine; Fluorphenazine; Fluphenazine; Fluphenazine Decanoate; Fluphenazine Hcl; Modecate; Modecate Concentrate; Moditen; Moditen Enanthate; Moditen Hcl; Omca; Pacinol; Permitil; Permitil Concentrate; Perphenazine; Pms Fluphenazine; Prolixin; Prolixin Concentrate; Prolixin Decanoate; Prolixin Enanthate; Prolixine; S 94; SQ 4918; Sevinol; Siqualine; Siqualon; Tensofin; Triflumethazine; Valamina; Vespazine; Yespazine

Drug Category:
Fluphenazine Decanoate is categorized under the following by the FDA: Antipsychotics; Phenothiazines; ATC:N05AB02

Dosage Forms:
LIQUID

Absorption:
Not Available

Interactions:
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Chemical IUPAC Name:
2-[4-[3-[2-(trifluoromethyl)-10H-phenothiazin-10-yl]propyl]piperazin-1-yl]ethanol





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