Folinic

This page contains recent news articles, when available, and an overview of Folinic but does not offer medical advice. You should contact your physician with regard to any health issues or concerns.

Regeneron Reports Third Quarter 2009 Financial and Operating Results  -  ‎Nov 3, 2009‎
One trial (called VELOUR) is evaluating aflibercept as a 2nd line treatment for metastatic colorectal cancer in combination with FOLFIRI (folinic acid ... Reuters

Amgen: Vectibix disappoints in colorectal cancer but hope remains  -  ‎Nov 6, 2009‎
Results from the recent Phase III CRYSTAL trial evaluating Erbitux in combination with FOLFIRI (folinic acid, fluorouracil, irinotecan) demonstrated that ... Trading Markets (press release)

60-Year-Old Drug Shows New Promise for Inherited Cancer  -  ‎Aug 27, 2009‎
Methotrexate is similar to a normal molecule called folinic acid, which is required for copying DNA. The drug prevents cells from making and repairing DNA Insciences Organisation

Cetuximab for Colorectal Cancer  -  ‎Aug 26, 2009‎
Cetuximab in combination with 5-FU, folinic acid and irinotecan (FOLFIRI), within its licensed indication, for the first-line treatment of metastatic PharmiWeb.com (press release)

Amgen Reports Mixed Results from Prospective Vectibix Study in ...  -  ‎Aug 19, 2009‎
...metastatic colorectal cancer and randomized them to receive either Vectibix and FOLFIRI (folinic acid, fluorouracil, and irinotecan) or just FOLFIRI. GenomeWeb Daily News

Regeneron Reports Second Quarter 2009 Financial and Operating Results  -  ‎Aug 4, 2009‎
One trial (called VELOUR) is evaluating aflibercept as a 2nd line treatment for metastatic colorectal cancer in combination with FOLFIRI (folinic acid FOXBusiness

Response Genetics, Inc. Reports Second Quarter 2009 Financial ...  -  ‎Aug 13, 2009‎
EGFR gene expression, a additional test for sensitivity to the widely used chemotherapy combination irinotecan, fluorouracil and folinic acid (FOLFIRI). FOXBusiness

Pancreatic Cancer: Advances in Medical Therapy  -  ‎Jul 6, 2009‎
Adjuvant 5-fluorouracil and folinic acid vs observation for pancreatic cancer: composite data from the ESPAC-1 and -3(v1) trials. Br. J. Cancer 100246–250 Medscape

KRAS Status Predicts Survival to Cetuximab Plus FOLFOX6 in ...  -  ‎Jun 29, 2009‎
KRAS experience longer survival times after treatment with cetuximab plus either folinic acid, fluorouracil, and irinotecan (FOLFIRI) or folinic acid, DG News

Adding Cetuximab to Standard Chemotherapy Improves Response Rates ...  -  ‎Jun 26, 2009‎
The study compared response rates in 111 patients with nonresectable colorectal liver metastases in response to the addition of cetuximab to either folinic DG News

Second-Line Treatment for PCP a Viable Alternative  -  ‎Jun 24, 2009‎
Neutrexin (trimetrexate) combined with Leucovorin (folinic acid) is an effective and safe treatment option for people who don't respond to their first AIDSmeds.com HIV/AIDS Treatment News

ASCO 2009:5-FUé?Žé‡?的解毒劑顯示相當有效  -  ‎Jun 25, 2009‎
...ä¸?é?Žï¼Œå°‘數其他化療的é?Žé‡?已經有其解毒劑,例如leucovorin (folinic acid)用於methotrexateé?Žé‡?。 von Borstelå?šå£«è§£é‡‹ï¼Œéœ€è¦?數天æ‰?能確èª?5-FU毒性,所以病患在é?Žé‡? 臺灣新浪網

Quando Usare la Chemioterapia? Mai se vuoi restare in vita  -  ‎Jul 7, 2009‎
Siamo in attesa di conoscere la percentuale di sopravvissuti a 2 e 5 anni [Felici A.: Bi-weekly chemotherapy with cisplatin, epirubicin, folinic acid and ECPlanet

Cetuximab in combination with irinotecan/5-fluorouracil/folinic ...  -  ‎Apr 14, 2009‎
...folinic acid (FA) and two different doses of infusional 5-fluorouracil (5-FU) in the first-line treatment of EGFR-detectable metastatic colorectal 7thSpace Interactive (press release)

Administering a combination of vitamins tetrahydrofolate and ...  -  18 Mar 2009
Dr Miyan explained: “A combination of tetrahydrofolate and folinic acid – both naturally occurring substances – stimulated brain cell growth and had a Media Newswire (press release)

Does Folic Acid Reduce the Toxicity of Methotrexate?  -  ‎Feb 19, 2009‎
The effect of folic acid and folinic acid supplements on purine metabolism in methotrexate-treated rheumatoid arthritis. Arthritis Rheum. 2004;50:3104-3111. Medscape

Packaging linked to drug mixups  -  ‎Feb 24, 2009‎
..."Folinic acid is easily mistaken for folic acid on a handwritten prescription." Were you the victim of a sentinel health error? Stuff.co.nz

Regeneron Reports Full Year and Fourth Quarter 2008 Financial and ...  -  ‎Feb 26, 2009‎
One trial is evaluating aflibercept as a 2nd line treatment for metastatic colorectal cancer (the VELOUR study) in combination with FOLFIRI (folinic acid MarketWatch (press release)

Biocompatibles International plc - Final 2008 Results  -  ‎Mar 5, 2009‎
FOLFIRI A chemotherapy regimen for the treatment of colorectal cancer, made up of the drugs FOLinic Acid (Leucovorin), Fluorouracil (5-FU) and IRInotecan FOXBusiness

Adjuvant chemotherapy and radiation following PDD for pancreatic ...  -  ‎Mar 11, 2009‎
3 Chemotherapy alone, or as maintenance following CRT, was 5-FU (425 mg/ m 2 ) and folinic acid (20 mg/m 2 ) administered on a 5-day schedule for 4 weeks American Journal of Hemotology and Oncology

Toxoplasmosis and HIV  -  Jan 21, 2009
This drug is also known as calcium leucovorin or folinic acid. Most people get better after about two to three weeks. You can get toxoplasmosis from cats guardian.co.uk,

Study into post-op chemotherapy  -  Jan 20, 2009
The patients were given the drug 5FU, which is available on the NHS, alongside folinic acid after surgery and had a five-year survival rate of 24%. The Press Association

Bilateral macular hemorrhage as a complication of drug induced ...  -  Jan 13, 2009
Prophylactic use of folinic acid could prevent such complications but in many cases, it is not prescribed owing to its cost or is mistakenly substituted 7thSpace Interactive (press release),

Drug therapy boosts survival rates  -  Jan 21, 2009
The research by experts at the University of Liverpool involved patients receiving the drug 5FU alongside folinic acid. About 7600 people are diagnosed with Pharmacy Europe,

Second-line chemotherapy drugs  -  Jan 21, 2009
The two drugs used most often for chemotherapy in colorectal cancer are 5-fluorouracil (5-FU) and leucovorin (also called folinic acid). guardian.co.uk,

Latest chemotherapy drugs help people with bowel cancer live longer  -  Jan 21, 2009
Chemotherapy for advanced bowel cancer often includes the drugs fluorouracil and leucovorin (also called folinic acid). The researchers imagined a patient guardian.co.uk,

The Evolving Role of EGFR Inhibitors in Colorectal Cancer—A Report ...  -  Jan 23, 2009
...(irinotecan 180 mg/m2, folinic acid 400 mg/m2, 5-fluorouracil bolus 400 mg/m2, and 5-fluorouracil infusion 2400 mg/m2 over 46 hours administered every Cancer Consultants,

Cetuximab Addition Well Tolerated, Allows Patients With ...  -  Jan 19, 2009
...followed by a 2400 mg/m 2 infusion, and folinic acid 400 mg/m 2 (FOLFOX6) or a similar regimen that replaced oxaliplatin with irinotecan (FOLFIRI). DG News

What's the evidence for chemotherapy?  -  Jan 21, 2009
Comparison of fluorouracil with additional levamisole, higher-dose folinic acid, or both, as adjuvant chemotherapy for colorectal cancer: a randomised trial guardian.co.uk,

Angiogenesis Inhibition in Early Breast Cancer: An Expert ...  -  Jan 13, 2009
...a 2-year period to receive FOLFOX6 [oxaliplatin, folinic acid, day 1 followed by a 5-FU bolus and infusion every 2 weeks], plus or minus bevacizumab. Medscape

New Data Reinforce Consistent Efficacy Profile Of Erbitux In 1st ...  -  Jan 14, 2009
Merck has also acquired the rights for the cancer treatment UFT® (tegafur-uracil) - an oral chemotherapy administered with folinic acid (FA) for the Medical News Today (press release),

Serial Transvaginal Sonographic Findings of Cervical Ectopic ...  -  Dec 23, 2008
...which was injected intravascularly at 100 mg/m 2 plus 200 mg/m 2 in 500 mL of a normal saline solution with folinic acid rescue. Journal of Ultrasound in Medicine (subscription)

Levoleucovorin (FUSILEVâ„¢) Listed in the NCCN Drugs & Biologics ...  -  Dec 11, 2008
FUSILEV is contraindicated for patients who have had previous allergic reactions attributed to folic acid or folinic acid. Due to calcium content, WELT ONLINE,

Merck Serono: European Commission Approves Erbitux For 1st-Line ...  -  Dec 1, 2008
Merck has also acquired the rights for the cancer treatment UFT® (tegafur-uracil) - an oral chemotherapy administered with folinic acid (FA) for the Medical News Today (press release),

Regeneron Reports Third Quarter 2008 Financial and Operating Results  -  Nov 4, 2008
One trial is evaluating aflibercept as a 2nd line treatment for metastatic colorectal cancer (the VELOUR study) in combination with FOLFIRI (folinic acid Trading Markets (press release),

Spectrum Pharmaceuticals Announces Third Quarter Corporate Update ...  -  Nov 7, 2008
FUSILEV is contraindicated for patients who have had previous allergic reactions attributed to folic acid or folinic acid. Due to calcium content, istockAnalyst.com (press release),

Spectrum Pharmaceuticals Files Supplemental New Drug Application ...  -  Oct 31, 2008
FUSILEV is contraindicated for patients who have had previous allergic reactions attributed to folic acid or folinic acid. Due to calcium content, MarketWatch

Merck KGaA: Overall Survival in First-Line NSCLC Reaches 15 Months  -  Nov 13, 2008
Merck has also acquired the rights for the cancer treatment UFT® (tegafur-uracil) – an oral chemotherapy administered with folinic acid (FA) for the PipelineReview.com (press release),

Overall Survival In 1st-line NSCLC Reaches 15 Months With Erbitux ...  -  Nov 14, 2008
Merck has also acquired the rights for the cancer treatment UFT® (tegafur-uracil) - an oral chemotherapy administered with folinic acid (FA) for the Medical News Today (press release),

FUSILEV(TM) Receives Unique, Product-Specific J-Code from the ...  -  Nov 9, 2008
FUSILEV is contraindicated for patients who have had previous allergic reactions attributed to folic acid or folinic acid. Due to calcium content, PR-Inside.com (Pressemitteilung),

Merck KGaA: Survival In 1st-Line Non-Small Cell Lung Cancer (NSCLC ...  -  Oct 3, 2008
Merck has also acquired the rights for the cancer treatment UFT® (tegafur-uracil) - an oral chemotherapy administered with folinic acid (FA) for the Medical News Today (press release),

Merck Serono’s Erbitux Nominated for International Prix Galien Award  -  Oct 15, 2008
Merck has also acquired the rights for the cancer treatment UFT® (tegafur-uracil) – an oral chemotherapy administered with folinic acid (FA) for the PharmaLive.com (press release),

Merck KGaA Submits New License Application for Erbitux in ...  -  Sep 11, 2008
Merck has also acquired the rights for the cancer treatment UFT® (tegafur-uracil) – an oral chemotherapy administered with folinic acid (FA) for the PharmaLive.com (press release),

Nutrition and Rheumatic Disease  -  Sep 2, 2008
...about management: supplement with 1 mg of folate daily and add folinic acid (leucovorin) 12 hours before and/or after the weekly methotrexate dose. Journal of American Medical Association (subscription),

Spectrum Pharmaceuticals Launches FUSILEV(TM)  -  Aug 17, 2008
FUSILEV is contraindicated for patients who have had previous allergic reactions attributed to folic acid or folinic acid. Due to calcium content, RedOrbit,

Regeneron Reports Second Quarter 2008 Financial and Operating Results  -  Jul 31, 2008
One trial is evaluating aflibercept as a 2nd line treatment for metastatic colorectal cancer in combination with FOLFIRI (Folinic Acid (leucovorin), MarketWatch

ASCO 2008: The Evolving Role of EGFR Inhibitors in Colorectal Cancer  -  Jul 31, 2008
...(irinotecan 180 mg/m2, folinic acid 400 mg/m2, 5-fluorouracil bolus 400 mg/m2, and 5-fluorouracil infusion 2400 mg/m2 over 46 hours administered every Cancer Consultants,

Merck Serono: Erbitux Phase III Clinical Study in Gastric Cancer ...  -  Jul 10, 2008
...(tegafur-uracil) - an oral chemotherapy administered with folinic acid (FA) for the first-line treatment of metastatic colorectal cancer. 뉴스와�어,

Biomarkers in Targeted Therapy for Colorectal Cancer  -  Jul 22, 2008
The CRYSTAL trial compared the use of folinic acid/fluorouracil/irinotecan (FOLFIRI) vs FOLFIRI plus cetuximab in the first-line treatment of metastatic Medscape (subscription)

An Expert Interview With Dr. Herbert Hurwitz  -  Jun 30, 2008
...[5] The CRYSTAL study, which evaluated FOLFIRI (folinic acid, 5-fluorouracil, and irinotecan) plus or minus cetuximab in patients with metastatic colon Medscape (subscription)

Treatments for chronic fatigue syndrome  -  Jun 30, 2008
The new injection, made of Hepapressin, glutathione, magnesium, vitamin B12, folic acid, folinic acid and trace elements (when administered weekly) yielded SheKnows.com,

Patients with KRAS Mutation Do Not Benefit from EGFR Inhibitors  -  Jun 20, 2008
...(irinotecan 180 mg/m2, folinic acid 400 mg/m2, 5-fluorouracil bolus 400 mg/m2, and 5-fluorouracil infusion 2400 mg/m2 over 46 hours administered every Cancer Consultants,

Merck Applies To Extend Use Of Erbitux For 1st-Line Head And Neck ...  -  Jun 20, 2008
Merck has also acquired the rights for the cancer treatment UFT® (tegafur-uracil) - an oral chemotherapy administered with folinic acid (FA) for the Medical News Today (press release),

Spectrum Pharmaceuticals Announces FUSILEVâ„¢ as Tradename for ...  -  Jun 17, 2008
FUSILEVâ„¢ is contraindicated for patients who have had previous allergic reactions attributed to folic acid or folinic acid. Due to calcium content, Business Wire (press release),

KRAS Predicts Which Colorectal Cancer Patients Will Benefit from ...  -  Jun 17, 2008
FOLFIRI, comprised of irinotecan 180 mg/m2, folinic acid 400 mg/m2, 5-fluorouracil bolus 400 mg/m2, and 5-fluorouracil infusion 2400 mg/m2 over 46 hours, RMGH Health News,

Addition of Cetuximab Improves Treatment of KRAS Wild-Type ...  -  Jun 3, 2008
By Bruce Sylvester CHICAGO -- June 3, 2008 -- Addition of cetuximab to folinic acid, 5-fluorouracil, and irinotecan (FOLFIRI) achieves a significant DG News

Cancer of the Esophagus and Stomach  -  Jun 14, 2008
Cetuximab has been combined with irinotecan-based chemotherapy (folinic acid- 5-FU-irinotecan regimen) in advanced gastric and GEJ cancer. RedOrbit,

Modified FOLFOX-6 chemotherapy in advanced gastric cancer: Results ...  -  May 27, 2008
The objective of this study was to evaluate the efficacy and toxicity of infusional 5-fluorouracil (5-FU), folinic acid and oxaliplatin (modified FOLFOX-6) 7thSpace Interactive (press release),

Sanofi-Aventis, Regeneron Pharma Present Update On Clinical ...  -  May 21, 2008
The companies also expect a Phase 2 1st-line study of aflibercept in metastatic colorectal cancer in combination with folinic acid, 5-FU, and oxaliplatin to RTT News,

Incidence, Impact, and Current Management Strategies for Treatment ...  -  May 22, 2008
Abstract Alpert JE, Mischoulon D, Rubenstein GE, Bottonari K, Nierenberg AA, Fava M. Folinic acid (leucovorin) as an adjunctive treatment for Medscape (subscription)

Adjunctive Bevacizumab Somewhat Beneficial in Metastatic ...  -  May 16, 2008
...or to fluorouracil/folinic acid plus oxaliplatin (FOLFOX-4) and then randomized them again to bevacizumab or placebo in a 2 x 2 factorial design. Cancerpage.com,

Erbitux Significantly Prolongs Survival in 1st-Line Treatment of ...  -  May 31, 2008
Merck has also acquired the rights for the cancer treatment UFT(R) (tegafur-uracil) - an oral chemotherapy administered with folinic acid (FA) for the PR Newswire Brasil (liberação de imprensa),

Antioxidants Do Not Help Development  -  Apr 15, 2008
One group was given a daily dose of antioxidants, one folinic acid, one a combination of antioxidants and folinic acid, and one a placebo. Advance for Speech-Language Pathologists and Audiologists,

Updates in the Management of Gastrointestinal Cancers: A Report ...  -  Mar 28, 2008
Randomized Phase III trial comparing infused irinotecan / 5-fluorouracil (5-FU)/folinic acid (IF) versus 5-FU/FA (F) in stage III colon cancer patients Cancer Consultants,

Chemotherapy Better Than Surgery Alone in Liver Metastases From ...  -  Apr 1, 2008
April 1, 2008 — Perioperative chemotherapy with the combination of cetuximab and oxaliplatin/5-fluorouracil/folinic acid (FOLFOX4) regimen in patients Medscape (subscription)





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