Fortovase

This page contains recent news articles, when available, and an overview of Fortovase but does not offer medical advice. You should contact your physician with regard to any health issues or concerns.


Overview:

Fortovase
(when available)

Pharmacology and use:
Saquinavir is a protease inhibitor with activity against Human Immunodeficiency Virus Type 1 (HIV-1). Protease inhibitors block the part of HIV called protease. HIV-1 protease is an enzyme required for the proteolytic cleavage of the viral polyprotein precursors into the individual functional proteins found in infectious HIV-1. Saquinavir binds to the protease active site and inhibits the activity of the enzyme. This inhibition prevents cleavage of the viral polyproteins resulting in the formation of immature non-infectious viral particles. Protease inhibitors are almost always used in combination with at least two other anti-HIV drugs. HIV-1 with advanced immunodeficiency together with antiretroviral nucleoside analogues

Mechanism Of Action:
Saquinavir inhibits the HIV viral proteinase enzyme which prevents cleavage of the gag-pol polyprotein, resulting in noninfectious, immature viral particles.

News Articles on Saquinavir

Fortovase (saquinavir): a complete guide from AIDSmeds.com  -  Nov 13, 2006
Fortovase is an anti-HIV medication. It is in a category of HIV medications called protease inhibitors (PIs). Fortovase prevents T-cells that have been ... AIDSmeds.com HIV/AIDS Treatment News

Fortovase.(Drug overview)  -  Jan 22, 2007
Fortovase is used in the treatment of advanced human immunodeficiency virus (HIV) infection. HIV causes the immune system to break down so that it can no ... Free with registration - PDR Family Guide to Prescription Drugs - AccessMyLibrary.com

Roche to discontinue US sale, distribution of Fortovase.  -  Feb 6, 2006
SAN FRANCISCO (MarketWatch) -- Roche Holdings Ltd. said Monday it plans to discontinue the US sale and distribution of Fortovase, the soft-gel formulation ... Free with registration - America's Intelligence Wire - AccessMyLibrary.com

… to Voluntarily Withdraw Anti-HIV Medication FORTOVASE(R) in Early ...  -  May 18, 2005
Roche to Voluntarily Withdraw Anti-HIV Medication FORTOVASE(R) in Early 2006. from PR Newswire. Highbeam Research – FREE Trial. Pay-Per-View - PR Newswire - HighBeam Research

Roche discontinues Fortovase.(Noted)  -  Jun 1, 2005
Roche discontinues Fortovase: Roche recently announced that it will discontinue the sale and distribution of its HIV therapy Fortovase (saquinavir). ... Free with registration - Pharmaceutical Processing - AccessMyLibrary.com

Saquinavir Side Effects from Consumer Reports Health.  -  Jan 10, 2005
Roche Pharmaceuticals has announced that Fortovase® brand saquinavir capsules will ... This action is not based on any known safety problems with Fortovase, ... consumerreports.org

Fortovase (saquinavir, free base) withdrawal of the marketing …  -  Aug 7, 2006
On 20 Aug 1998 the European Commission issued a marketing authorisation valid throughout the European Union for the medicinal product Fortovase, ... Pay-Per-View - EMEA (European Medicines Agency) - Factiva, from Dow Jones

Roche to discontinue Hivid and Fortovase due to lack of demand  -  Mar 22, 2005
Roche announced this week that it will discontinue production of two of its antiretroviral products, Hivid (zalcitabine, ddC) and Fortovase (soft gel ... Aidsmap

Fortovase withdrawal.(Branded Drugs)(Brief Article)  -  Jun 6, 2005
Hoffmann-La Roche Inc. plans to voluntarily withdraw Fortovase, its anti-HIV ... Roche says Fortovase is being discontinued because of reduced clinical demand. Free with registration - Chain Drug Review - AccessMyLibrary.com

Press Release: Roche to Focus Resources on Availability of INVIRASE(R...  -  Feb 6, 2006
Company Voluntarily Ceases Sale and Distribution of Fortovase(R) In the U.S. - ... Comparing pharmacokinetics of INVIRASE/r or FORTOVASE/r Two studies ... Pay-Per-View - PR Newswire - HighBeam Research

Panacos Announces New Board Member.  -  Oct 26, 2006
INVIRASE and FORTOVASE are trademarks of Hoffmann-LaRoche Inc. Except for the historical information contained herein, statements made herein, ... Free with registration - Business Wire - AccessMyLibrary.com

Fortovase withdrawal.  -  Jun 6, 2005
Hoffmann-La Roche Inc. plans to voluntarily withdraw Fortovase, ... Roche says Fortovase is being discontinued because of reduced clinical demand. ... $9.94 - Chain Drug Review - Alacra Store

Article: Fortovase withdrawal.(Branded Drugs)(Brief Article) - Chain...  -  Jun 6, 2005
Fortovase withdrawal.(Branded Drugs)(Brief Article) ... find Chain Drug Review articles. Hoffmann-La Roche Inc. plans to voluntarily withdraw Fortovase, ... Pay-Per-View - Chain Drug Review - HighBeam Research

Article: Roche discontinues Fortovase.(Noted) - Pharmaceutical …  -  Jun 1, 2005
Roche discontinues Fortovase.(Noted) ... find Pharmaceutical Processing articles. Roche discontinues Fortovase: Roche recently announced that it will ... Pay-Per-View - Pharmaceutical Processing - HighBeam Research

HN75 Fortovase beter de koelkast in  -  Jul 10, 2007
Naar ervaring van meerdere gebruikers van Fortovase kun je deze proteaseremmer niet lang buiten de koelkast bewaren, al suggereert de bijsluiter van het ... Hiv Vereniging Nederland

500mg Invirase tablet approved in Europe  -  May 27, 2005
The 500mg tablet cuts the pill burden substantially for people taking saquinavir, and is also better tolerated than the Fortovase formulation of saquinavir, ... Aidsmap

New Study Results Find That Patients Treated With Boosted INVIRASE, A...  -  Jul 25, 2005
The efficacy of INVIRASE with ritonavir or FORTOVASE (with or without ... INVIRASE(R) (saquinavir mesylate) capsules and FORTOVASE(R) (saquinavir) soft ... $4.95 - PR Newswire - ECNext

Roche AIDS drug may be pulled out of India  -  Aug 11, 2006
Roche has taken this action because the clinical demand for Fortovase has ... Fortovase is an anti HIV drug and is taken along with ritonavir and other ... Financial Express

Door Hiv Vereniging Nederland  -  Jul 10, 2007
Volgens de fabrikant zouden die bijwerkingen deels verklaard kunnen worden door het gebruik van Fortovase in deze trial. Met Invirase, de andere versie van ... Hiv Vereniging Nederland

The Times - <b>R - Z</b>  -  Oct 22, 2008
A later formulation of Saquinavir (Fortovase), packaged in a soft gel capsule, ... The recommended dose of Fortovase is twice (he recommended dose of the ... The Times

Kort medisch: Kaletra-tabletten  -  Jul 10, 2007
In Hivnieuws 101 stond onder het kopje 'Kaletra-tabletten' abusievelijk een stukje over Fortovase uit Hivnieuws 98. Onze excuses. Het nieuwsbericht is wel ... Hiv Vereniging Nederland

Roche to take weak-selling AIDS drug off market.  -  May 19, 2005
The company, which plans |to stop selling Fortovase in early 2006, ... "The Fortovase formulation no longer meets the demands of convenience and ... Free with registration - The Record - AccessMyLibrary.com

Roche to take weak-selling AIDS drug off market | Article from The...  -  May 19, 2005
Roche announced Wednesday that it plans to stop selling its Fortovase AIDS drug ... The company, which plans to stop selling Fortovase in early 2006, ... Pay-Per-View - The Record - HighBeam Research

Invirase (saquinavir, SQV)  -  Mar 1, 2008
Fortovase, otra versión de saquinavir, fue aprobada en 1997. ... La información de la página de Fortovase seguirá vigente para personas VIH positivas que ... AIDSmeds.com HIV/AIDS Treatment News

Roche stopt met ddC en Fortovase; introduceert Invirase 500 mg  -  Mar 23, 2005
Roche Nederland heeft meegedeeld ze de levering van ddC en Fortovase binnen afzienbare tijd wereldwijd willen beëindigen. Roche is hierover in overleg met ... Hiv Vereniging Nederland

Roche sắp ngừng bán thuốc Fortovase trị HIV  -  May 20, 2005
Tập đoàn dược phẩm Roche của Thụy Sỹ sẽ ngừng bán thuốc Fortovase trị HIV vào đầu năm 2006 do nhu cầu thuốc này giảm đáng kể. Tuy nhiên, thuốc Invirase dạng ... VietNamNet

Article: Tough pill: Prescription instructions causing confusion -...  -  Nov 30, 2006
Article: Twice-Daily HIV Regimen With FORTOVASE(R) and ... PR Newswire; October 31, 2001 ; 700+ words ... ... conducted clinical studies evaluating a ... Pay-Per-View - Chicago Sun-Times - HighBeam Research

Roche to Pull HIV/AIDS Drug Due to Dwindling Demand  -  May 18, 2005
Roche has decided to discontinue the sale and distribution of the HIV/AIDS drug Fortovase (saquinavir), the company announced today, because clinical demand ... Daily News Central

Press Release: New Diabetes Compound AVE0010 Showed Clear Dose …  -  Jun 7, 2008
Article: Twice-Daily HIV Regimen With FORTOVASE(R) and ... PR Newswire; October 31, 2001 ; 700+ words ... ... conducted clinical studies evaluating a ... Pay-Per-View - PR Newswire - HighBeam Research

Schor v. Abbott Laboratories, 457 F.3d 608 (7th Cir. 07/26/2006)  -  Jul 26, 2006
For example, a standard dose of FORTOVASE® (saquinavir) is 1200 mg three times a day; when combined with NORVIR, however, FORTOVASE is effective in doses of ... $2.95 - U.S. Court of Appeals, Seventh Circuit - VersusLaw

HIV/AIDS Therapy; Study shows effectiveness of protease inhibitor in ...  -  Aug 24, 2005
The efficacy of INVIRASE with ritonavir or FORTOVASE (with or without ritonavir ... INVIRASE (saquinavir mesylate) capsules and FORTOVASE (saquinavir) soft ... Pay-Per-View - Vaccine Weekly - Factiva, from Dow Jones

Article: Correction.(Opinion)(Correction notice) - Family Practice...  -  Oct 15, 2006
Article: Twice-Daily HIV Regimen With FORTOVASE(R) and ... PR Newswire; October 31, 2001 ; 700+ words ... ... conducted clinical studies evaluating a ... Pay-Per-View - Family Practice News - HighBeam Research

Article: Winter cough drives me mad; Complimentary medicine.(Features)...  -  Dec 3, 2006
Article: Twice-Daily HIV Regimen With FORTOVASE(R) and ... PR Newswire; October 31, 2001 ; 700+ words ... ... conducted clinical studies evaluating a ... Pay-Per-View - Sunday Mail - HighBeam Research

Press Release: Abbott Submits Application to US FDA for a New, More …  -  May 3, 2005
Article: FORTOVASE with Kaletra Shows Encouraging Results Among ... ... Study, FORTOVASE with Kaletra reduced HIV-RNA plasma levels to ... ... Pay-Per-View - PR Newswire - HighBeam Research

Ã?ndice de lecciones  -  Mar 1, 2008
Crixivan puede aumentar los niveles en la sangre de Fortovase (saquinavir en ... Invirase y Fortovase no afectan los niveles de Crixivan (no existen ... AIDSmeds.com HIV/AIDS Treatment News

LaSalud.com.mx - Por que la salud es primero  -  Feb 14, 2008
Fortovase fue finalmente retirado del mercado en 2007, cuando Roche apostó otra vez por saquinavir, con una nueva formulación que, potenciada con ritonavir, ... LaSalud.com.mx

Calidad de vida - eluniversal.com  -  Jun 13, 2005
Roche cambia el Fortovase. Ante las noticias acerca del retiro del mercado del inhibidor de proteasa Fortovase, Roche nos envió una nota para "destacar que ... El Universal - El Universal (Venezuela)

Press Release: Merck, Pfizer Releases Data on Drugs to Treat Diabetes....  -  Jun 25, 2007
Article: FORTOVASE with Kaletra Shows Encouraging Results Among Protease ... PR Newswire; March 1, 2002 ; 700+ words ... ... undetectable levels of HIV on a ... Pay-Per-View - M2 Presswire - HighBeam Research

Article: Jarlsberg Reserve, a stronger version of the Norwegian...  -  Dec 2, 2006
...the stage for thousands of patients to switch medicines. Hoffman-La Roche's Fortovase, the improved version of the protease inhibitor saquinavir, will ... Pay-Per-View - Grocer - HighBeam Research

Article: Tx for noncompliant H. pylori patients.(CLINICAL CAPSULES)( …  -  Dec 1, 2005
Article: Twice-Daily HIV Regimen With FORTOVASE(R) and ... ... 1000 mg FORTOVASE with 100 mg ritonavir twice daily, an investigational dosage . ... Pay-Per-View - Pediatric News - HighBeam Research

Article: New twists in topical psoriasis therapies.(Dermatologic...  -  Aug 1, 2005
Article: Twice-Daily HIV Regimen With FORTOVASE(R) and ... PR Newswire; October 31, 2001 ; 700+ words ... ... conducted clinical studies evaluating a ... Pay-Per-View - Skin & Allergy News - HighBeam Research

Article: New dosing.(RXs)(Brief article) - Chain Drug Review |...  -  Apr 23, 2007
Article: New dosing for Invirase and Fortovase.(FDA ... HIV Treatment: ALERTS!; June 1, 2004 ; 504 words ...In December, the FDA approved new dosing ... Pay-Per-View - Chain Drug Review - HighBeam Research

Press Release: /CORRECTION - Schering-Plough Corporation/. - PR …  -  Jan 11, 2008
Article: FORTOVASE with Kaletra Shows Encouraging Results Among Protease ... PR Newswire; March 1, 2002 ; 700+ words ... ... undetectable levels of HIV on a ... Pay-Per-View - PR Newswire - HighBeam Research

Press Release: New Study Results Show Asenapine More Effective Than …  -  Dec 17, 2007
Article: FORTOVASE with Kaletra Shows Encouraging Results Among Protease ... PR Newswire; March 1, 2002 ; 700+ words ... ... undetectable levels of HIV on a ... Pay-Per-View - PR Newswire - HighBeam Research

Reyataz Oral : Uses, Side Effects, Interactions, Pictures, Warnings &...  -  Sep 30, 2008
Fortovase (saquinavir) US prescribing information. Roche Laboratories, Inc. December, 2004. 13.Invirase (saquinavir mesylate) US prescribing information. ... WebMD

Ritonavir Oral : Uses, Side Effects, Interactions, Pictures, Warnings...  -  Sep 30, 2008
Fortovase (saquinavir) US prescribing information. Roche Laboratories, Inc. December, 2004. 9.Invirase (saquinavir mesylate) US prescribing information. ... WebMD

Calidad de vida - eluniversal.com  -  May 18, 2005
La farmacéutica suiza dijo que Fortovase será descontinuado en el primer trimestre del 2006 debido a la disponibilidad de una versión mejorada del ... El Universal - El Universal (Venezuela)

Actualité des traitements  -  Mar 2, 2006
L'absence d'Hivid® (zalcitabine) et de Fortovase® (saquinavir) dans les recommandations du groupe d'experts (Rapport Delfraissy 2004) dans les indications ... Act Up-Paris

Article: Monthly and daily dosing of ibandronate similarly effective.(...  -  Jan 15, 2005
AIDS Weekly; May 7, 2001 ; 700+ words ... ... and antiviral activity with once-daily dosing of its protease inhibitor Fortovase ... weeks. ... Pay-Per-View - Internal Medicine News - HighBeam Research

Nicht nur Medikamente schicken  -  Feb 7, 2007
Um das Übertragungsrisiko auf ihre Kinder so niedrig wie möglich zu halten, nahm die schwangere Ruth das Medikament Fortovase, einen Proteasehemmer, ... derStandard.at

MEDIZIN TEIL 10 – Spezialisten für AIDS, HAUT- UND …  -  Nov 5, 2007
Vor zwei Wochen erfolgte etwa in den USA die Zulassung des Proteasehemmers Fortovase. Der bereits bekannte Wirkstoff (Saquinavir) wurde in eine neue „Hülle“ ... FOCUS Online

Prudential Insurance Co. of America v. Life Partners, Inc., No. 07...  -  May 8, 2008
He previously had been treated with Kaletra, Viread, AZT, DDI, Viramune, Norvir, Viracept, Ziagen, Sustiva, Trizivir, Fortovase and Crixivan. ... $2.95 - U.S. District Court, District of... - VersusLaw

Sooner the better for AIDS treatment | Article from The Record...  -  Oct 27, 2008
Although the data on Roche's new drug, Fortovase, are preliminary, Levin said, "It ... The Record (Bergen County, NJ). Article: AROUND THE WORLD ... Pay-Per-View - The Record - HighBeam Research

THE ESSENTIALS  -  Jul 25, 2007
HIV drugs: saquinavir (Fortovase, Invirase), indinavir (Crixivan). Immunosuppressant drugs: cyclosporine (Neoral, Sandimmune), tacrolimus (Prograf) ... Pay-Per-View - Providence Journal - ProQuest Archiver

Article: Ibandronate shots better in those with GI intolerance.( …  -  Nov 1, 2006
Article: FORTOVASE with Kaletra Shows Encouraging Results Among Protease ... ... Fourteen patients required initial FORTOVASE ... primarily due to ... Pay-Per-View - Family Practice News - HighBeam Research

Grapefruit Juice Bad Mix With Some Rx Drugs  -  Jan 20, 2005
...vinblastine, vincristine, Dextromethorphan (found in many over-the-counter cold medicines), Agenerase, Crixivan, Viracept, Norvir, Fortovase, Proscar, ... FOXNews

Kombinasjonen rifampicin og ritonavir/sakinavir: Legemiddelindusert …  -  Jul 4, 2005
I studien, utført av produsenten av Fortovase/Invirase – Roche, utviklet 39,3% ... Produsenten av Fortovase og Invirase (begge inneholder sakinavir), Roche, ... Statens legemiddelverk

Virginian-Pilot, The : gRAPEFRUIT, ITS JUICE CAN INTERFERE WITH …  -  Jul 30, 2007
HIV drugs: saquinavir (Fortovase, Invirase), indinavir (Crixivan). * Immunosuppressant drugs: cyclosporine (Neoral, Sandimmune), tacrolimus (Prograf) ... $2.95 - Virginian-Pilot - NewsBank

Article: Novel agent improves GI function in pain patients.(Pain...  -  Oct 1, 2006
Article: FORTOVASE with Kaletra Shows Encouraging Results Among Protease ... PR Newswire; March 1, 2002 ; 700+ words ... ... occurred in two patients and ... Pay-Per-View - Clinical Psychiatry News - HighBeam Research

IAC: HIV Care Guidelines Expand Treatment Eligibility  -  Aug 3, 2008
...including lopinavir (Kaletra), atazanavir (Reyataz), fosamprenavir (Lexiva), darunavir (Prezista), and saquinavir (Fortovase, Invirase). ... MedPage Today

Article: FDA ordered Centocor to add a new warning on hepatotoxicity...  -  Mar 1, 2005
Article: New warning added to Fortovase labeling.(by ... Medical Marketing & Media; April 1, 2001 ; 700+ words ...* Hoffmann-LaRoche has added a new warning ... Pay-Per-View - Medical Marketing & Media - HighBeam Research

Article: Valsartan indicated for cutting post-MI death risk.(Rx) -...  -  Sep 15, 2005
Article: FORTOVASE with Kaletra Shows Encouraging Results Among Protease ... PR Newswire; March 1, 2002 ; 700+ words ... ... undetectable levels of HIV on a ... Pay-Per-View - Internal Medicine News - HighBeam Research

Levitra Oral : Uses, Side Effects, Interactions, Pictures, Warnings &...  -  Oct 24, 2006
Fortovase (saquinavir) US prescribing information. Roche Laboratories, Inc. December, 2004. 7.Invirase (saquinavir mesylate) US prescribing information. ... WebMD

Descontinúan 39 fármacos mercado de Estados Unidos  -  Jul 30, 2007
USP), Flovent Rotadisk, en polvo para inhalación, Fortovase (saquinavir) en cápsulas de 200 mg, Humulin U Ultralente, HIVID (zalcitabine) en tabletas, ... Listín Diario

Loislaw Federal District Court Opinions - BECKWITHE v. BARNHART ( …  -  Mar 10, 2005
At the time of the hearing before the ALJ, Plaintiff was on several types of medication, including Fortovase, Zerit, Epivir, as well as BC Powder and ... Pay-Per-View - Loislaw Federal District Court Opinions - Loislaw

Eating grapefruit can work against several prescription medications  -  Nov 16, 2008
Cancer medications include Sandimmune, Tacrolimus and Fortovase. Grapefruit will increase these blood levels and can cause toxicity. ... News Chief

Loislaw Federal District Court Opinions - SCHOR v. ABBOTT …  -  Jul 12, 2005
At least seven other boosted PIs, not manufactured by defendant, are boosted by Norvir: Agenerase, Crixivan, Fortovase, Invirase, Lexiva, Reyataz, ... Pay-Per-View - Loislaw Federal District Court Opinions - Loislaw

Roche extends 2 AIDS drug trials | Article from The Record (Bergen …  -  Jan 18, 2006
Fortovase, a more potent version of the protease inhibitor-type AIDS drug introduced by Hoffmann-La Roche Inc. of Nutley two years ... ... Pay-Per-View - The Record - HighBeam Research

'Empty stomach' direction is not to be ignored | Article from The...  -  Sep 5, 2006
Roche applied for FDA approval to market Fortovase in May, following clinical trials involving nearly 1 ... The Record (Bergen County, NJ) ... Pay-Per-View - The Record - HighBeam Research

St. Paul Pioneer Press : MANY MEDS DON'T MIX WITH THE SUN  -  Sep 21, 2005
...oxytetracycline (Terra-mycin), pyrazinamide, ritonavir (Norvir), saquinavir (Fortovase, Invirase), sulfamethoxazole/tri-methoprim (Bactrim), ... $2.95 - St. Paul Pioneer Press - NewsBank

Philanthropic Roche shares manufacturing technology with Africa  -  Jun 4, 2007
Invirase and Fortovase (saquinavir) saw a 28 per cent increase to 182m Swiss francs (€110m), as a result of an increase in the use of the recently ... In-PharmaTechnologist.com

How to take Erlotinib from Consumer Reports Health.  -  Jan 12, 2008
...indinavir (Crixivan), nelfinavir (Viracept), ritonavir (Norvir), and saquinavir (Fortovase, Invirase); H2 blockers such as cimetidine (Tagamet), ... consumerreports.org

Study shows drug helps obese teenagers lose weight. | Article from …  -  Jun 15, 2005
Hoffman-La Roche, maker of Fortovase, supplies doctors ... associate clinical director for Hoffman-La Roche, said from Geneva. He dismissed the . ... Pay-Per-View - Washington Times - HighBeam Research

YM BioSciences Strengthens Program Management of Lead Drugs.  -  Apr 3, 2007
La-Roche Inc. with leadership responsibility through NDA filings and certain of the approvals for Xeloda(TM), Fortovase(TM), Zenapax(TM), Xenical(TM). ... Free with registration - PR Newswire - AccessMyLibrary.com

Other FDA Advisories:  -  Jun 1, 2005
...with marked transaminase elevations after taking simultaneous regimens of rifampin (Rifadin) and ritonavir (Norvir)-boosted saquinavir (Fortovase). ... Pay-Per-View - American Family Physician - Factiva, from Dow Jones

Gilead rains manufacturing deals on India's generic firms  -  Sep 26, 2006
African companies free of charge with the technical expertise to manufacture a generic version of its HIV protease inhibitor Fortovase (saquinavir). ... In-PharmaTechnologist.com

How to take Ziprasidone from Consumer Reports Health.  -  Jan 4, 2007
...and saquinavir (Fortovase, Invirase); hormonal contraceptives (birth control pills, rings, patches, implants, and injections); lovastatin (Mevacor, ... consumerreports.org

Large analysis shows benefits of starting treatment with efavirenz  -  Aug 23, 2006
The boosted protease inhibitors included were amprenavir (Agenerase), lopinavir (Kaletra), saquinavir (Invirase / Fortovase) and indinavir (Crixivan): newer ... Aidsmap

HIV Patients May Be at Risk of Heart Problems When Taking Protease …  -  Feb 17, 2005
Brand names include Kaletra, Viracept, Crixivan, Norvir and Fortovase. The researchers emphasize that the drugs' therapeutic benefits are still greater than ... Free with registration - AScribe Medicine News Service - AccessMyLibrary.com

HIV patients may be at risk of heart problems when taking protease …  -  Feb 19, 2005
Brand names include Kaletra, Viracept, Crixivan, Norvir and Fortovase. The researchers emphasize that the drugs' therapeutic benefits are still greater than ... Medical News Today - Medical News Today (press release)

HIV Patients May Be At Risk Of Heart Problems When Taking Protease …  -  Feb 21, 2005
Brand names include Kaletra, Viracept, Crixivan, Norvir and Fortovase. The researchers emphasize that the drugs' therapeutic benefits are still greater than ... sciencedaily.com

NGN Capital's Managing General Partner Georg Nebgen Joins Javelin …  -  Dec 11, 2006
...development team activities for Invirase/Fortovase. Dr. Nebgen obtained his doctorate in Pharmaceutical Technology Sciences from the University of Bonn, ... Free with registration - Business Wire - AccessMyLibrary.com

How to take Doxazosin from Consumer Reports Health.  -  Jan 3, 2007
...nelfinavir (Viracept), ritonavir (Norvir, in Kaletra), or saquinavir (Fortovase, Invirase); medications for irritable bowel disease, motion sickness, ... consumerreports.org

Tipranavir continues to show benefit in treatment-experienced...  -  Nov 30, 2005
...from a choice of ritonavir-boosted lopinavir (Kaletra), indinavir (Crixivan), saquinavir (Invirase / Fortovase) or amprenavir (Agenerase). ... Aidsmap

CD4-guided structured treatment interruptions safe in patients at...  -  Feb 9, 2005
These patients went on to receive three years of highly active antiretroviral therapy (HAART) with ritonavir-boosted soft-gel saquinavir (Fortovase), ... Aidsmap

Delavirdine (Systemic).(Drug overview)  -  Aug 1, 2006
Fortovase) -- Use of this medicine with delavirdine may increase the amount of saquinavir in your body Sildenafil (eg, Viagra) -- Use of this medicine ... Free with registration - USP DI-Volume II, Advice for the... - AccessMyLibrary.com

Generic name product may also be available in the US  -  Jul 28, 2005
Choledyl) or Quinidine (eg, Quinidex) or Ritonavir (eg, Norvir) or Saquinavir (eg, Fortovase, Invirase) or Theophylline (eg, Theo-Dur, Somophyllin-T) or ... Free with registration - USP DI-Volume II, Advice for the... - AccessMyLibrary.com

Exploiting natural HIV defence  -  Feb 9, 2007
Next came HIV protease inhibitors such as Roche's Invirase/Fortovase (saquinavir), Abbott Laboratories Norvir (ritonavir), Merck & Co's Crixivan (indinavir) ... DrugResearcher.com

Sildenafil (Systemic).(Drug overview)  -  May 1, 2006
Nizoral) Mibefradil (eg, Posicor) Ritonavir (eg, Norvir) Saquinavir (eg, Fortovase or Invirase) -- These medicines may increase the unwanted effects of ... Free with registration - USP DI-Volume II, Advice for the... - AccessMyLibrary.com

Fluticasone.(Drug overview)  -  Jan 22, 2007
...fluticasone with ketoconazole (Nizoral) or HIV drugs known as protease inhibitors, including Agenerase, Crixivan, Fortovase, Norvir, and Viracept. ... Free with registration - PDR Family Guide to Prescription Drugs - AccessMyLibrary.com

Hydroxyurea (Systemic).(Drug overview)  -  May 1, 2006
Viramune) or Ritonavir (eg, Norvir) or Saquinavir (eg, Fortovase) or Saquinavir mesylate (eg, Invirase) or Stavudine (eg D4T, Zerit) or Zalcitabine (eg, ... Free with registration - USP DI-Volume II, Advice for the... - AccessMyLibrary.com

GSK lets Chinese firm manufacture flu drug  -  Oct 5, 2006
African companies free of charge with the technical expertise to manufacture a generic version of its HIV protease inhibitor Fortovase (saquinavir). In-PharmaTechnologist.com

How to take Sildenafil from Consumer Reports Health.  -  Jan 12, 2007
...ritonavir (Norvir, in Kaletra), saquinavir (Fortovase, Invirase), and tipranavir (Aptivus); nevirapine (Viramune); other medications or devices to treat ... consumerreports.org

Cyclosporine (Systemic).  -  Feb 1, 2006
Diflucan) or Human immunodeficiency virus (HIV) protease inhibitors (eg, Crixivan, Fortovase, Invirase, Norvir, Viracept) or Imatinib (eg, ... Free with registration - USP DI-Volume II, Advice for the... - AccessMyLibrary.com

Ritonavir (Systemic).  -  Feb 1, 2006
Flagyl) or Rifabutin (eg, Mycobutin) or Rifampin (eg, Rifadin) or Saquinavir (eg, Fortovase, Invirase) or Sildenafil (eg, Viagra) or Theophylline (eg, ... Free with registration - USP DI-Volume II, Advice for the... - AccessMyLibrary.com

Eplerenone (Systemic).  -  Oct 27, 2005
...which may increase the chance of side effects Erythromycin [eg, E-Mycin] or Fluconazole [eg, Diflucan] or Saquinavir [eg, Fortovase] or Verapamil [eg, ... Free with registration - USP DI-Volume II, Advice for the... - AccessMyLibrary.com

Rifampin (Systemic).(Drug overview)  -  Aug 1, 2006
Choledyl) or Quinidine (eg, Quinidex) or Ritonavir (eg, Norvir) or Saquinavir (eg, Fortovase, Invirase) or Theophylline (eg, Theo-Dur, Somophyllin-T) or ... Free with registration - USP DI-Volume II, Advice for the... - AccessMyLibrary.com

Rifampin Plus Ritonavir-Boosted Saquinavir Therapy Linked to High...  -  Feb 10, 2005
...saquinavir/saquinavir mesylate (Fortovase/Invirase) as part of combination antiretroviral therapy (ART) due to a high risk of hepatotoxicity. ... Medscape

Lopinavir/ritonavir not linked to hepatotoxicity regardless of HCV...  -  Jan 25, 2005
...indinavir boosted with 200-400 mg daily ritonavir (94 patients), saquinavir (Invirase, Fortovase) plus 800 mg daily ritonavir (273 patients), ... Aidsmap

Risk of diabetes increased by being HIV-positive and on HAART  -  Jun 3, 2005
...the four most commonly used protease inhibitors: ritonavir (Norvir), nelfinavir (Viracept), saquinavir (Invirase / Fortovase) and indinavir (Crixivan). ... Aidsmap

Brand Names/Synonyms:
Fortovase is also known by the following brand names and/or synonymsFortovase; Invirase; ROC; SAQUINAVIR; SQV; Saquinavir; Saquinavir Mesylate; Saquinavir [Usan]

Drug Category:
Fortovase is categorized under the following by the FDA: Anti-HIV Agents; Anti-HIV Agents; ATC:J05AE01

Dosage Forms:
INVIRASE (saquinavir mesylate) capsules and FORTOVASE (saquinavir) soft gelatin capsules

Absorption:
Absolute bioavailability of saquinavir administered as INVIRASE averaged 4%

Interactions:
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Chemical IUPAC Name:
N-[1-benzyl-2-hydroxy-3-[3-(tert-butylcarbamoyl)-1,2,3,4,4a,5,6,7,8,8a-decahydroisoquinolin-2-yl]-propyl]-2-quinolin-2-ylcarbonylamino-butanediamide





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