Gemfibrozil

This page contains recent news articles, when available, and an overview of Gemfibrozil but does not offer medical advice. You should contact your physician with regard to any health issues or concerns.


Overview:

Gemfibrozil
(when available)

Pharmacology and use:
Gemfibrozil, a fibric acid antilipemic agent similar to clofibrate, is used to treat hyperlipoproteinemia and as a second-line therapy for type IIb hypercholesterolemia. For treatment of adult patients with very high elevations of serum triglyceride levels (Types IV and V hyperlipidemia) who present a risk of pancreatitis and who do not respond adequately to a determined dietary effort

Mechanism Of Action:
Gemfibrozil increases the activity of extrahepatic lipoprotein lipase (LL), thereby increasing lipoprotein triglyceride lipolysis. Chylomicrons are degraded, VLDLs are converted to LDLs, and LDLs are converted to HDL. This is accompanied by a slight increase in secretion of lipids into the bile and ultimately the intestine. Gemfibrozil also inhibits the synthesis and increases the clearance of apolipoprotein B, a carrier molecule for VLDL.

News Articles on Gemfibrozil

Favorable Vote from FDA Advisory Committee on Benefit/Risk of CRESTOR(R ...  -  ‎Dec 15, 2009‎
...increased with concurrent administration of some other lipid-lowering therapies (fibrates or niacin), gemfibrozil, cyclosporine, or lopinavir/ritonavir. ... CNNMoney.com (press release)

Advisory Committee Briefing Materials for CRESTOR(R) sNDA Available on US FDA ...  -  ‎Dec 11, 2009‎
...increased with concurrent administration of some other lipid-lowering therapies (fibrates or niacin), gemfibrozil, cyclosporine, or lopinavir/ritonavir. ... CNNMoney.com (press release)

Lipoprotein A: Genvariante steigert Herzinfarktrisiko  -  ‎Dec 28, 2009‎
Die VA-HIT-Studie gibt Evidenz für eine kardiovaskuläre Risikoreduktion durch eine HDL-steigernde Therapie mit Gemfibrozil. Die Assoziation zwischen hohen ... Deutsches Ärzteblatt

Kolasa: High triglycerides? Here are 10 tips that will help  -  ‎Nov 11, 2009‎
If these measures don't work, your doctor will talk with you about taking a medication like nicotinic acid (Niacin), fibrates like Gemfibrozil (Lopid) and ... Greenville Daily Reflector

What Risks Are Associated With High-Dose Rosuvastatin?  -  ‎Oct 22, 2009‎
A reduced initial dose should be considered in patients receiving fibrates or niacin; coadministration with gemfibrozil should be avoided. ... Medscape

EU Committee To Size Up Abbott, Solvay Cholesterol Drugs  -  ‎Oct 26, 2009‎
In addition to fenofibrates, the referral procedure will examine the drugs bezafibrate, ciprofibrate and gemfibrozil. EMEA spokesman Martin Harvey said ... Wall Street Journal

Statins such as Lipitor and Zocor can damage your liver and kidneys  -  ‎Nov 8, 2009‎
These include gemfibrozil, erythromycin (Erythrocin), antifungal medications, nefazodone (Serzone), cyclosporine and niacin. If you take statins and have ... Examiner.com

Red Yeast Rice and Hyperlipidemia: How Strong Is the Evidence?  -  ‎Oct 28, 2009‎
...[3] Of note, the risk for rhabdomyolysis is increased approximately 10 times among patients who have used a statin along with gemfibrozil. ... Medscape

Local Fish Eat Our Sunblock, Deodorant, and Valium  -  ‎Nov 4, 2009‎
All the samples of treated sewage contained ibuprofen, naproxen and the lipid-lowering drug gemfibrozil. Among the 37 chemicals found in the hornyhead ... San Diego Reader

Beoordelings- en verwijzingsprocedures CHMP [2]  -  ‎Oct 28, 2009‎
De CHMP startte een verwijzingsprocedure voor fibraten (fenofibraat, bezafibraat, ciprofibraat en gemfibrozil) door bezorgdheid over het klinische voordeel ... Medical facts

Early gemfibrozil therapy beneficial in dyslipidemia  -  Apr 12, 2006
Patients with dyslipidemia benefit from early gemfibrozil treatment, particularly if they have coronary heart disease (CHD) risk factors related to the ... Medwire (subscription)

Rifampin markedly decreases and gemfibrozil increases the plasma …  -  Jan 5, 2005
Janne T. Backman MD 1 , Harri Luurila MD 1 , Mikko Neuvonen MSc 1 and Pertti J. Neuvonen MD 1. 1 Department of Clinical Pharmacology, University of Helsinki ... Nature.com

Gemfibrozil (Systemic).  -  Oct 27, 2005
Gemfibrozil (gem-FI-broe-zil) is used to lower cholesterol and triglyceride (fat-like substances) levels in the blood. This may help prevent medical ... Free with registration - USP DI-Volume II, Advice for the... - AccessMyLibrary.com

Gemfibrozil's benefit seen in kids with severe metabolic syndrome.( …  -  Jun 1, 2007
NEW ORLEANS -- Gemfibrozil produces multiple benefits in children with severe ... The gemfibrozil-induced decrease in the elevated levels of alanine ... Free with registration - Family Practice News - AccessMyLibrary.com

Scottsdale tap water nearly pharmaceutical-free  -  Jun 26, 2008
...carbamazepine, sulfamethoxazole, fluoxetine, estradiol, estrone, ethynylestradiol, testosterone, progesterone, gemfibrozil, ibuprofen and triclosan. East Valley Tribune

Gemfibrozil Improves Some Risk Parameters in Children With Metabolic ...  -  Mar 26, 2007
By Danny Kucharsky. NEW ORLEANS, LA -- March 26, 2007 -- Gemfibrozil treatment significantly reduces triglycerides, raises levels of high-density ... DG News

Drug changes hair color  -  Mar 16, 2006
I take enalapril, verapamil, Levothroid and gemfibrozil. I would appreciate any help you ... Gemfibrozil (Lopid) may also cause constipation or diarrhea. ... $2.95 - Buffalo News - NewsBank

Gemfibrozil aids severe metabolic syndrome.(Clinical Rounds)(Brief …  -  Aug 1, 2007
NEW ORLEANS -- Gemfibrozil produces multiple benefits in children with severe metabolic syndrome, including a sharp reduction in triglyceride levels, ... Free with registration - Pediatric News - AccessMyLibrary.com

Sun Pharma gets USFDA nod for Gemfibrozil tablets  -  Dec 31, 2008
Sun Pharmaceutical Industries` US subsidiary has received final approval from the US Food and Drug Administration (USFDA) to market Gemfibrozil tablets, ... Myiris.com

Efficacy of Atorvastatin and Gemfibrozil, Alone and in Low Dose …  -  Jan 1, 2006
Departments of Endocrinology and Biochemistry (OJ, RB, JO-L.), Hospital Sant Pau, and Department of Biochemistry and Molecular Biology, Universitat Autònoma ... Journal of Clinical Endocrinology and...

… : With statin, fenofibrate safer than gemfibrozil: risk for...  -  Oct 1, 2005
With statin, fenofibrate safer than gemfibrozil: risk for rhabdomyolysis increased significantly when gemfibrozil was combined with most statins. Pay-Per-View - Internal Medicine News - HighBeam Research

Pioglitazone Linked to Drug Interactions With Gemfibrozil, Rifampin  -  Mar 13, 2007
Te FDA approved safety labeling revisions for the antidiabetic agents pioglitazone and pioglitazone/metformin to warn of interactions associated with ... Diabetes In Control

Managing Your Triglycerides  -  Feb 23, 2008
Since 1988 I am taking Gemfibrozil 600 mg and Niacin 500 mg twice daily. I take Gemfibrozil half an hour before lunch and dinner. ... HealthCentral.com

Statins Urged for Diabetic Patients: Presented at EAS  -  May 2, 2005
In the Veterans Administration HDL Intervention Trial, 2531 men with cardiovascular disease were randomised to receive gemfibrozil in a dose of 1200 mg per ... DG News

Gemfibrozil doesn't slow renal decline.(Clinical Capsules)(Brief...  -  Feb 1, 2005
Even though gemfibrozil cuts triglyceride and total cholesterol levels while raising HDL cholesterol, it does not slow renal decline in patients with mild ... Pay-Per-View - Family Practice News - Factiva, from Dow Jones

Article: Gemfibrozil aids severe metabolic syndrome.(Clinical...  -  Aug 1, 2007
Gemfibrozil aids severe metabolic syndrome.(Clinical Rounds)(Brief article)(Clinical report) ... find Pediatric News articles. NEW ORLEANS -- Gemfibrozil ... Pay-Per-View - Pediatric News - HighBeam Research

Tests home in on new hope against bird flu  -  Jan 19, 2008
..."When we tried gemfibrozil, it worked so well, we ran with it." ... According to Alleva, the benefits of gemfibrozil - if it worked in humans - could be ... The Australian

Article: Gemfibrozil does not slow renal decline.(CLINICAL CAPSULES)(...  -  Jan 15, 2005
Even though gemfibrozil cuts triglyceride and total cholesterol levels while raising HDL cholesterol, it does not slow renal decline in patients with mild ... Pay-Per-View - Internal Medicine News - HighBeam Research

Is it time to stop using Fibrates?  -  Mar 5, 2007
These include: Clofibrate, Gemfibrozil and Fenofibrate. This would lead to the assumption that fibrates will reduce the risk of heart and major vessel ... Virtual Medical Centre - The Virtual Medical Centre

Bellow Falls, Vt., pharmacist arrested on numerous charges.  -  Aug 4, 2006
On March 16, Illingworth reportedly admitted to loss prevention officers he took 20 bottles of hydrocodone, 364 gemfibrozil pills, which is a cholesterol ... Free with registration - Eagle Times - AccessMyLibrary.com

Multitherapy for diabetes -- Ménard and Ardilouze 175 (10): 1247 -- …  -  Nov 7, 2006
Trials have been conducted with gemfibrozil, 2 , 3 bezafibrate, 4 clofibrate 5 and ... The observation that the cardioprotective effects of gemfibrozil were ... CMAJ

Fibric acid derivatives for high cholesterol  -  Jul 11, 2008
Gemfibrozil or fenofibrate is prescribed for people who have very high ... Gemfibrozil may be used to reduce the risk of heart attack in people with ... MSN Health & Fitness

Le gemfibrozil diminue le risque d'AVC chez les hommes coronariens …  -  Nov 25, 2006
Rubins HB, Davenport J, Babikian V, et al, for the VA-HIT Study Group. Reduction in stroke with gemfibrozil in men with coronary heart disease and low HDL ... EBM Journal (Abonnement)

… kontraindikasjon: NovoNorm skal ikke brukes sammen med gemfibrozil  -  Oct 20, 2007
Det europeiske kontor for legemiddelvurdering (EMEA) og dets vitenskapelige komité (CPMP) er gjort kjent med ny sikkerhetsinformasjon vedrørende ... Statens legemiddelverk

Fibrate/statin called safer combo therapy.(Cardiovascular Medicine)  -  Oct 1, 2005
Treatment with gemfibrozil appears to boost the maximum concentration and the area ... This effect appears to occur because statins and gemfibrozil are ... Free with registration - Family Practice News - AccessMyLibrary.com

Article: AP investigation details pharmaceuticals found in watersheds...  -  Mar 10, 2008
Cincinnati: 4 (gemfibrozil, ibuprofen, sulfamethaxazole and ethinyl estradiol) ... Oklahoma City: 12 (including acetaminophen, fluoxetine, gemfibrozil, ... Pay-Per-View - Deseret News - HighBeam Research

… nel lungo periodo nei pazienti dislipidemici trattati con Gemfibroz...  -  Jun 23, 2006
Lo studio era finalizzato a valutare l'efficacia del Gemfibrozil ( Lopid ) nella ... Circa due terzi dei partecipanti di entrambi i gruppi ( Gemfibrozil, ... XagenaSalute

What are effective medication combinations for dyslipidemia?(CLINICAL...  -  Jan 1, 2006
EVIDENCE-BASED ANSWER Most combination therapies increase the risk of intolerance or side effects, including myopathy. The statin/gemfibrozil combination ... $4.95 - Journal of Family Practice - ECNext

Statin-Drug Interactions: Update on the Most Common and Clinically …  -  Sep 15, 2005
Other agents such as gemfibrozil also increase the risk of myopathy, ... Gemfibrozil inhibits OATP2, and has been shown to increase rosuvastatin plasma ... $4.95 - Consultant - ECNext

Cheaper approaches to flu divide researchers  -  Aug 30, 2007
Gemfibrozil is a fibrate, a class of drug widely prescribed to lower lipid concentrations in the blood. But it also inhibits the release of inflammatory ... Nature.com

Statins: Are these cholesterol-lowering drugs right for you?  -  Mar 28, 2008
Certain other cholesterol-lowering drugs, such as gemfibrozil (Lopid) and niacin, increase the ... These include gemfibrozil, erythromycin (Erythrocin), ... CNN International

Gemfibrozil riduce mortalità a lungo termine in obesi dislipidemici  -  Jun 19, 2006
Un prolungamneto a 18 anni del follow-up del Helsinky Heart study dimostra che la mortalità globale è ridotta nel gruppo gemfizobril rispetto al gruppo ... Pillole.org

Rischi cardiovascolari con un nuovo farmaco antidiabete, Muraglitazar  -  Dec 2, 2005
Farmaci ad attività sul PPAR-alfa sono i derivati dell'Acido Fibrico, Fenofibrato e Gemfibrozil. Questi farmaci modulano il metabolismo lipidico abbassando ... XagenaSalute

Mistaken Medication: A Hard Pill to Swallow  -  Dec 20, 2006
She explained to me that neither gemfibrozil nor Vicodin is actually dispensed by human pharmacists but by a robot, and she speculated that the robot must ... LegalNewsTV USA

The Role of Fibrates in a Statin World  -  Apr 10, 2006
Gemfibrozil has clearly stood the test of time. Its long-term safety and efficacy, in both primary and secondary prevention, have been established. ... Archives of Internal Medicine

Fibrate/statin called safer combo therapy.(Cardiovascular Medicine) |...  -  Oct 1, 2005
Treatment with gemfibrozil appears to boost the maximum concentration and the area ... This effect appears to occur because statins and gemfibrozil are ... Pay-Per-View - Family Practice News - HighBeam Research

Ten dermatology drug interactions to watch.(Skin Disorders)  -  Feb 15, 2006
Bexarotene and gemfibrozil. "Bexarotene has been a godsend for patients with ... Unfortunately, gemfibrozil raises bexarotene levels, and there have been ... Free with registration - Family Practice News - AccessMyLibrary.com

Fibrates: What Have We Learned in the Past 40 Years?  -  Apr 24, 2007
With the introduction of gemfibrozil in the 1980s came a renewed interest in ... The widely prescribed fibrates in the United States include gemfibrozil and ... Medscape

Derm drug interactions: top ten to watch for.(Rx)  -  Feb 1, 2006
Bexarotene and gemfibrozil. "Bexarotene has been a godsend for patients with ... Unfortunately, gemfibrozil raises bexarotene levels, and there have been ... Free with registration - Internal Medicine News - AccessMyLibrary.com

Loislaw Federal District Court Opinions - BOBAY v. WALGREEN …  -  Aug 5, 2008
On April 14, 2005, Dr. Mark Hazen called in a Gemfibrozil prescription for Ms. Bobay to the Bluffton Walgreen store. The prescription was filled on that ... Pay-Per-View - Loislaw Federal District Court Opinions - Loislaw

Severe hypertriglyceridemia with a history of treatment failure  -  May 17, 2005
Because of his history of dyspepsia with fenofibrate, gemfibrozil was ... Since gemfibrozil was tolerated, the dose was increased to 600 mg twice daily. ... Nature.com

Management of hypertriglyceridemia.(Disease/Disorder overview)  -  May 1, 2007
...(18,19) When combined with statins, gemfibrozil may increase serum statin ... Compared with gemfibrozil/statin therapy, fenofibrate/statin therapy has a ... Free with registration - American Family Physician - AccessMyLibrary.com

Derm drug interactions: top ten to watch for.(Dermatologic Therapy) |...  -  Mar 1, 2006
Bexarotene and gemfibrozil. "Bexarotene has been a godsend for patients with ... Unfortunately, gemfibrozil raises bexarotene levels, and there have been ... Pay-Per-View - Skin & Allergy News - HighBeam Research

Arteriosclerosis of the Extremities  -  May 15, 2008
Gemfibrozil (Lopid) is the standard fibrate. Newer fibrates, including fenofibrate (Tricor) and bezafibrate (Bezalip), may be more effective in lowering ... New York Times

Management of hypertriglyceridemia.(Disease/Disorder overview)  -  May 1, 2007
...(18,19) When combined with statins, gemfibrozil may increase serum statin ... Compared with gemfibrozil/statin therapy, fenofibrate/statin therapy has a ... $4.95 - American Family Physician - ECNext

What's the evidence for fibrates for people who don't have heart...  -  Nov 6, 2008
We found one study that looked at the effects of the drug gemfibrozil over five years ... Helsinki Heart Study: primary-prevention trial with gemfibrozil in ... guardian.co.uk

Adverse Events Related to Muraglitazar Use in Diabetes  -  May 3, 2006
One of the 3 large studies examining the use of gemfibrozil in the secondary prevention ... 2 Another study showed a nonsignificant benefit for gemfibrozil, ... Journal of American Medical Association - Journal of American Medical Association...

Six different drugs in Elgin's water? Officials not worried  -  Sep 12, 2008
Six drugs - carbamazepine, continine, gemfibrozil, monensin, ... Gemfibrozil is a cholesterol medicine. And monensin is a veterinary antibiotic, ... Chicago Daily Herald - Chicago Daily Herald

Maintain good vigilance for statin side effects, interactions.( …  -  Jul 15, 2006
If it is necessary to use both gemfibrozil and a statin--a common scenario--it's ... Article: With statin, fenofibrate safer than gemfibrozil: risk for ... ... Pay-Per-View - Internal Medicine News - HighBeam Research

Amiodarone Interacts with Simvastatin but not with Pravastatin...  -  Nov 9, 2006
Kyrklund, C., Backman, JT, Neuvonen, M. & Neuvonen, PJ Gemfibrozil increases plasma pravastatin concentrations and reduces pravastatin renal clearance. ... Nature.com

A Randomized Trial of a Strategy for Increasing High-Density Lipoprote...  -  Jan 22, 2005
Intervention: Gemfibrozil, niacin, and cholestyramine or corresponding placebos, ... The Helsinki Heart Study (9) examined the use of gemfibrozil in primary ... RedOrbit

Severe statin-induced problems rare in diabetes: statin users had...  -  Jul 15, 2006
Article: With statin, fenofibrate safer than gemfibrozil: risk for ... ... 252 atherosclerotic patients receiving a statin plus gemfibrozil, ... Pay-Per-View - Internal Medicine News - HighBeam Research

Merck/Schering-Plough Announces Update for the IMPROVE-IT Trial.  -  Nov 15, 2005
Gemfibrozil: In a study of twelve healthy adult males, concomitant administration of gemfibrozil (600 mg twice daily) significantly increased the oral ... Free with registration - Business Wire - AccessMyLibrary.com

Konsumsi Makanan Berkolesterol Dapat Sebabkan Hiperlipidemia  -  Sep 25, 2008
Obat yang termasuk dalam golongan asam fibrat adalah gemfibrozil, fenofibrate, ... Gemfibrozil sangat efektif dalam menurunkan trigliserid plasma. ... Okezone

Merck's Investigational Extended-Release Niacin/Laropiprant ( …  -  Nov 5, 2007
Gemfibrozil: Coadministration of gemfibrozil (600 mg twice daily for 3 days) with simvastatin (40 mg daily) resulted in clinically significant increases in ... Free with registration - Business Wire - AccessMyLibrary.com

Maintain good vigilance for statin side effects, interactions.( …  -  Jul 15, 2006
If it is necessary to use both gemfibrozil and a statin--a common scenario--it's important to document the reason. Also, educate the patient about myalgias ... Free with registration - Internal Medicine News - AccessMyLibrary.com

HIV and hyperlipidemia: current recommendations and treatment.( …  -  Feb 1, 2006
In 19 of the 25 patients on gemfibrozil, atorvastatin was added due to the ... The combined effect of gemfibrozil and atorvastatin reduced the total ... $4.95 - MedSurg Nursing - ECNext

Does raising high-density lipoprotein cholesterol level benefit...  -  Feb 25, 2005
Treatment with gemfibrozil, niacin and cholestyramine, in conjunction with diet and lifestyle changes, can increase HDL cholesterol levels, ... Nature.com

Konsumsi Makanan Berkolesterol Dapat Sebabkan Hiperlipidemia  -  Sep 29, 2008
Obat yang termasuk dalam golongan asam fibrat adalah gemfibrozil, fenofibrate, ... Gemfibrozil sangat efektif dalam menurunkan trigliserid plasma. ... Portal CBN

Be careful when buying medication online | Article from New Straits...  -  Feb 26, 2007
...group was voluntarily ... lowering medicine, gemfibrozil," an FDA statement read. "Fatal rhabdomyolysis ... in combination with gemfibrozil. ... Pay-Per-View - New Straits Times - HighBeam Research

Should we target HDL-cholesterol to reduce coronary heart disease...  -  Nov 14, 2005
Trial (LRC-CPPT), of 10% with gemfibrozil in the Helsinki Heart Study, of 6% with gemfibrozil in the Veterans Affairs HDL Intervention Trial (VA-HIT), ... Nature.com

Pharmacist suspended - Suspect faces theft accusations  -  Jun 12, 2006
The camera also caught him taking gemfibrozil, an anticholesterol drug. When confronted by the company investigators, Illingworth allegedly admitted to ... $2.95 - Rutland Herald - NewsBank

Article: Positive buzz around cholesterol drug Crestor unlikely to...  -  Mar 14, 2006
PR Newswire; August 12, 2004 ; 700+ words ... ... gemfibrozil or antacids. CRESTOR is not right for everyone ... a doctor right away. ... Pay-Per-View - AP Worldstream - HighBeam Research

A 47-year-old man with eruptions on his trunk.(Clinical report)  -  Jul 1, 2006
It is believed that fenofibrate undergoes a different pathway of glucuronidation than gemfibrozil. Most statins undergo glucuronidation in the same family ... $4.95 - Journal of Family Practice - ECNext

Management of diabetic dyslipidemia: doing the right thing  -  May 30, 2006
Surprisingly, two trials of gemfibrozil were found to reduce coronary events as effectively as statins did in three of the four outcome measures, ... Nature.com

New Study Showed VYTORIN(R) (ezetimibe/simvastatin) Significantly …  -  Jun 18, 2006
Gemfibrozil: In a study of twelve healthy adult males, concomitant administration of gemfibrozil (600 mg twice daily) significantly increased the oral ... Free with registration - Business Wire - AccessMyLibrary.com

New Analysis Showed VYTORIN(R) (ezetimibe/simvastatin) Superior to …  -  Mar 13, 2006
Gemfibrozil: In a study of twelve healthy adult males, concomitant administration of gemfibrozil (600 mg twice daily) significantly increased the oral ... Free with registration - Business Wire - AccessMyLibrary.com

Merck and Schering-Plough to Develop Another New Cholesterol …  -  Mar 26, 2007
Gemfibrozil: In a study of twelve healthy adult males, concomitant administration of gemfibrozil (600 mg twice daily) significantly increased the oral ... $4.95 - Business Wire - ECNext

Data Analysis Showed VYTORIN(R) (ezetimibe/simvastatin) Significantly...  -  Mar 13, 2006
Gemfibrozil: In a study of twelve healthy adult males, concomitant administration of gemfibrozil (600 mg twice daily) significantly increased the oral ... $4.95 - Business Wire - ECNext

FDA Approves New Label for VYTORIN(R) (ezetimibe/simvastatin).  -  Oct 5, 2006
Gemfibrozil: In a study of twelve healthy adult males, concomitant administration of gemfibrozil (600 mg twice daily) significantly increased the oral ... $4.95 - Business Wire - ECNext

Drugs found in suburban cities' drinking water  -  Sep 12, 2008
Aurora's water found gemfibrozil. Chicago's contained a cholesterol medication and a nicotine derivative. Many cities found the anticonvulsant carbamazepine ... $2.95 - Daily Herald - NewsBank

New Analysis Showed VYTORIN(R) (ezetimibe/simvastatin) Superior to …  -  Mar 13, 2006
Gemfibrozil: In a study of twelve healthy adult males, concomitant administration of gemfibrozil (600 mg twice daily) significantly increased the oral ... $4.95 - Business Wire - ECNext

Merck's Investigational Extended-Release Niacin/Laropiprant ( …  -  Nov 5, 2007
Gemfibrozil: Coadministration of gemfibrozil (600 mg twice daily for 3 days) with simvastatin (40 mg daily) resulted in clinically significant increases in ... $4.95 - Business Wire - ECNext

Data Recently Published in Mayo Clinic Proceedings Showed VYTORIN( …  -  Dec 21, 2006
Gemfibrozil: In a study of twelve healthy adult males, concomitant administration of gemfibrozil (600 mg twice daily) significantly increased the oral ... $4.95 - Business Wire - ECNext

GRAEDONS | People's Pharmacy Drugs turn reader's hair from white to …  -  Mar 11, 2006
I take enalapril, verapamil, Levothroid and gemfibrozil. I would appreciate any help you ... Gemfibrozil (Lopid) may also cause constipation or diarrhea. ... Youngstown Vindicator

Medicamentos en el río  -  Jan 17, 2006
Gemfibrozil, diclofenaco, carbamezapina, ibuprofeno... El agua del Ebro está llena de estos y otros muchos compuestos. ... El País - El País (España)

Lipid-Lowering Drugs Protect Against Peripheral Diabetic Neuropathy  -  Jun 23, 2007
At the end of the longitudinal study, gemfibrozil continued to be the primary fibrate used, although some had begun to use fenofibrate. ... Medical News Today - Medical News Today (press release)

Actos, controindicazioni, interazioni, effetti indesiderati  -  Apr 24, 2007
La co-somministrazione di Pioglitazone con Gemfibrozil ( un inibitore del citocromo P450 2C8 ) ha comportato un aumento di 3 volte dell'AUC del Pioglitazone ... XagenaSalute

Dawka leku a wystąpienie miopatii  -  Apr 4, 2007
W kilku opracowaniach, w tym i firm farmaceutycznych, spotkałem się z opinią, że wśród fibratów gemfibrozil jest lekiem, który najczęściej wywołuje miopatię ... Puls Medycyny

Independent Nurse: Clinical focus - Hyperlipidaemia.(care and...  -  Mar 31, 2006
Gemfibrozil showed some CHD benefit in primary prevention patients,4 and was also found to benefit those with low HDL and low LDL.5 Note that gemfibrozil ... Free with registration - GP - AccessMyLibrary.com

Early Fibrate Therapy Found to Cut Heart Mortality  -  Apr 10, 2006
...with dyslipidemia who were given early treatment with Lopid (gemfibrozil), according to an 18-year follow-up of patients in the Helsinki Heart Study. ... MedPage Today

Abstract and Introduction  -  Mar 16, 2006
Helsinki Heart Study: primary prevention trial with gemfibrozil in middle-aged men with dyslipidemia: safety of treatment, changes in risk factors, ... Medscape

High-Dose Statins in Acute Coronary Syndromes  -  Jan 5, 2005
Gemfibrozil for the secondary prevention of coronary heart disease in men with low levels of high-density lipoprotein cholesterol. N Engl J Med. ... Journal of American Medical Association - Journal of American Medical Association...

Drug Changes Hair Color  -  Mar 18, 2006
I take enalapril, verapamil, Levothroid and gemfibrozil. I would appreciate any help you ... Gemfibrozil (Lopid) may also cause constipation or diarrhea. ... RedOrbit

Diabetics benefit from statins.(Clinical report)  -  Jul 15, 2006
The use of statins or gemfibrozil reduced the risk of a first major coronary event by 21% in diabetic patients and by 23% in nondiabetics. ... Free with registration - Internal Medicine News - AccessMyLibrary.com

CK determinations in asymptomatic patients on statins  -  May 26, 2006
...(2) Never give gemfibrozil with a statin. Gemfibrozil blocks the glucuronidation of all of the statins, producing toxic levels. Fenofibrate appears to be ... Cortlandt Forum

Generics makers keep new products coming.(RX/GENERICS)(Statistical …  -  Sep 17, 2007
Gemfibrozil $79807334.84 Watson Labs Necon $79337469.00 Novartis Vivelle-DOT $79094483.73 Sandoz Triamterene w/HCTZ $78733450.29 Par Pharm. ... Free with registration - Chain Drug Review - AccessMyLibrary.com

Brigham and Women's Hospital  -  Feb 11, 2005
The best known fibrate is gemfibrozil (brand name: Lopid). ... Here's the good news: Pooled data on gemfibrozil and other fibrates show they lower total ... Intelihealth.com

Lowering LDL targets  -  Feb 20, 2006
First, adding gemfibrozil to a statin results in a fatal rhabdomyolysis because gemfibrozil interferes with the glucuronidation of all statins, ... Cortlandt Forum

Global top 300 multisource generic pharmaceuticals by sales, …  -  Apr 28, 2008
Fexofenadine HCI 00093725201 135 Apotex Gemfibrozil 60505003408 136 Watson Labs Hydrocodone-acetaminophen 00591038705 137 Sandoz Fentanyl 00781711155 ... $20.00 - Chain Drug Review - Alacra Store

Illinois Appellate Court Reports - JENSEN v. BAYER AG, 371 Ill....  -  Feb 2, 2007
They can occur with statin monotherapy, although the risk appears to be increased significantly by concomitant use of gemfibrozil (Lopid). ... Pay-Per-View - Illinois Appellate Court Reports - Loislaw

Lipid-lowering therapies reduce development of peripheral neuropathy.  -  Aug 1, 2007
At the end of the longitudinal study, the majority of patients receiving fibrates were treated with gemfibrozil, although some patients received fenofibrate ... $9.94 - Formulary - Alacra Store

CME questions.  -  Feb 1, 2005
...a. Cervistatin alone b. Gemfibrozil alone c. Other statins alone d. Gemfibrozil plus cervistatin Answers: 7. (b); 8. (d); 9. (a); 10. (d) Pay-Per-View - Clinical Cardiology Alert - Factiva, from Dow Jones

Loislaw Federal District Court Opinions - IN RE BAYER AG SECURITIES …  -  Sep 14, 2005
In December 1999, Bayer Corp. revised the Baycol label to include a warning that Baycol should not be prescribed with gemfibrozil. (Compl. ¶ 69. ... Pay-Per-View - Loislaw Federal District Court Opinions - Loislaw

Lipid drugs have varying effects on overall mortality.(Patient...  -  Jul 1, 2005
Fibrates (gemfibrozil and others) actually increase overall mortality and at the same time decrease cardiac mortality. (Level of evidence [LOE]=1a) $4.95 - Journal of Family Practice - ECNext

Genetic Risk Factors for Myopathies Induced by Lipid-Lowering Drugs  -  Oct 1, 2006
Fifteen patients were taking statins, 2 were taking gemfibrozil, and one was taking fenofibrate. One patient was taking a statin and gemfibrozil. ... Pay-Per-View - Neurology Alert - Factiva, from Dow Jones

Factiva Search  -  Jan 15, 2005
Even though gemfibrozil cuts triglyceride and total cholesterol levels while raising HDL cholesterol, it does not slow ... Copyright 2005 Gale Group. ... Pay-Per-View - Internal Medicine News - Factiva, from Dow Jones

Article: Study: Crestor Not As Effective As Hoped - AP Online |...  -  Mar 25, 2007
PR Newswire; August 12, 2004 ; 700+ words ... ... gemfibrozil or antacids. CRESTOR is not right for everyone ... a doctor right away. ... Pay-Per-View - Associated Press/AP Online - HighBeam Research

United States top 250 generic drugs by retail sales and manufacturer...  -  Apr 23, 2007
Gemfibrozil $62204488.42 Teva USA Clonazepam $62043027.63 Sandoz Loratadine $61997663.28 Qualitest Hydrocodone w/APAP $61864963.25 Par Pharm. ... $20.00 - Chain Drug Review - Alacra Store

United States top 190 multisource generic drugs ranked by sales in …  -  Sep 29, 2008
Gemfibrozil 153 Watson Labs Hydrocodone-acetaminophen 154 Apotex Corp. ... Oxcarbazepine 176 Teva USA Gemfibrozil 177 Barr Fentanyl citrate 178 Teva USA ... $20.00 - Chain Drug Review - Alacra Store

Brand Names/Synonyms:
Gemfibrozil is also known by the following brand names and/or synonymsApo-Gemfibrozil; Ausgem; Bolutol; Brozil; CCRIS 318; CHEMBANK796; CI 719; CI-719; Cholespid; Clearol; Decrelip; Elmogan; Fetinor; Fibratol; Fibrocit; GFZ; Gem-S; Gemd; Gemfibril; Gemfibromax; Gemfibrozil; Gemfibrozil [Usan:Ban:Inn]; Gemfibrozilo [Inn-Spanish]; Gemfibrozilum [Inn-Latin]; Gemlipid; Gemnpid; Gen-Fibro; Genlip; Gevilon; Gevilon Uno; Gozid; Hidil; Hipolixan; Innogen; Ipolipid; Jezil; Lanaterom; Lifibron; Lipazil; Lipigem; Lipira; Lipizyl; Lipozid; Lipur; Litarek; Lopid; Low-Lip; Micolip; Normolip; Novo-Gemfibrozil; Nu-Gemfibrozil; Pilder; Po-Gemfibrozil; Polyxit; Progemzal; Reducel; Regulip; Renabrazin; Sinelip; Synbrozil; TEVA-A; Taborcil; Tentroc; Trialmin; Uno; Wl-Gemfibrozil; [Usan:Ban:Inn]

Drug Category:
Gemfibrozil is categorized under the following by the FDA: Antilipemic Agents; Fribic Acid Derivatives; ATC:C10AB04

Dosage Forms:
CAPSULE; TABLET

Absorption:
Well absorbed from GI after oral administration (within 1-2 hours)

Interactions:
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Chemical IUPAC Name:
5-(2,5-dimethylphenoxy)-2,2-dimethyl-pentanoic acid





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