Glucagon

This page contains recent news articles, when available, and an overview of Glucagon but does not offer medical advice. You should contact your physician with regard to any health issues or concerns.


Overview:

Glucagon
(when available)

Pharmacology and use:
Used in the treatment of hypoglycemia and in gastric imaging, glucagon increases blood glucose concentration and is used in the treatment of hypoglycemia. Glucagon acts only on liver glycogen, converting it to glucose through the release of insulin. It also relaxes the smooth muscles of the gastrointestinal tract. For treatment of severe hypoglycemia, also used in gastrointestinal imaging

Mechanism Of Action:
Glucagon binds the glucagon receptor which then initiates a dual signaling pathway using both adenylate cyclase activation and increased intracellular calcium. Glucagon receptors are found in the liver, kidney, brain and pancreatic islet cells. The glucagon mediated signals lead to an increase in insulin excretion

News Articles on Glucagon recombinant

Byetta increases blood sugar during exericse  -  ‎Nov 10, 2009‎
Byetta is a drug which stimulates insulin secretion while suppressing glucagon secretion. It works by stimulating a receptor found on cells of the pancreas. ... Examiner.com

Eating Quickly Makes You Gain Weight  -  ‎Nov 10, 2009‎
Blood samples taken at the time of and during the experiment revealed that slower eaters had higher amounts of the hormones peptide YY and glucagon-like ... University of Virginia The Cavalier Daily

Researchers recommend adopted peak GH to ITT diagnostic cutoff point for GHD  -  ‎Nov 9, 2009‎
In another study, the researchers further examined the diagnostic value of the glucagon test as an alternative to the insulin tolerance test and arginine. ... Endocrine Today

New DPP4 inhibitor launched  -  ‎Nov 12, 2009‎
These incretin hormones stimulate insulin secretion and suppress glucagon production; consequently, blood glucose levels fall. Administered as a once daily ... Healthcare Republic

Pacing yourself during dinner limits overeating: Study  -  ‎Nov 4, 2009‎
...the "hunger" hormone, and two other hormones that trigger feelings of being full called peptide YY (PYY) and Glucagon-like peptide (GLP-1). ... The Gazette (Montreal)

How to respond when a diabetic has low blood sugar  -  ‎Nov 4, 2009‎
The other is to administer a shot of glucagon. Glucagon shots can be purchased with a doctor's prescription. They are expensive (about $100 a shot), ... Examiner.com

Jean Grant-Sutton  -  ‎Nov 13, 2009‎
Stress plays a big role in glucagon secretion. Yoga effectively reduces stress by lowering cortisol, adrenaline, and noradrenalin levels in the body. ... Petaluma Argus Courier

On the Pulse - 13th November 2009  -  ‎Nov 13, 2009‎
A paper in the Lancet assesses liraglutide, a glucagon-like peptide-1 agonist with an extended half-life, in 564 non-diabetic obese patients. ... OnMedica

Organ Lessons: The Pancreas  -  ‎Nov 10, 2009‎
In its endocrine duties, the pancreas produces insulin and glucagon, the hormones that lower and raise blood-sugar levels. Diabetes (both type 1 and type 2) ... FitSugar.com (blog)

Paladin Reports Record Third Quarter 2009 Financial Results  -  ‎Nov 11, 2009‎
During the quarter, Paladin announced that the Biologics and Genetic Therapies Directorate of Health Canada had approved GlucaGen(R) (recombinant glucagon ... Benzinga

LY2189265 Add-On Treatment Offers Positive Changes in Metabolic Effects in ...  -  ‎Oct 23, 2009‎
GLP-1 decreases secretion of glucagon from the pancreas, increases pancreatic secretion of insulin in a glucose-dependent fashion, and increases the mass ... DG News

Adelaide study confirms beneficial effects of GLP-1 on gastric emptying  -  ‎Nov 11, 2009‎
A study in Adelaide has confirmed that glucagon-like peptide-1 (GLP-1) has an important physiological role in slowing the rate of gastric empty and ... Endochrinology Update

Dear Medical Health Professional,  -  ‎Nov 7, 2009‎
This means emergency contacts, sources of food in the house, ginger ale, and crackers, glucagon, lots of water, and a phone handy because you just might ... Diabetes Health (press release)

Roche announces that primary endpoint in first phase III clinical trial of ...  -  ‎Oct 29, 2009‎
...phase III clinical study using Taspoglutide, the first human once weekly glucagon-like peptide-1 (GLP-1) analogue originating from Ipsen's Research. ... Trading Markets (press release)

Once weekly diabetes treatment promising in first Phase III trial  -  ‎Nov 2, 2009‎
This incretin hormone lowers blood glucose levels by regulating the secretion of insulin and glucagon. Unlike the two currently approved GLP-1 analogues ... Healthcare Republic

David A. Kaufmann: Eat, drink and be weary for tomorrow you diet!  -  ‎Oct 19, 2009‎
If the glucose in your blood drops, glucagon, another hormone from the pancreas, is secreted which converts stored glycogen to glucose for burning. ... Gainesville Sun

ironguides: Dawn Phenomenon & Glycogen Metabolism of Swimming  -  ‎Nov 6, 2009‎
Cortisol, Glucagon), which can lead to the overproduction of glucose by the liver and to the underutilization of glucose by peripheral tissues. ... Xtri.com

Ligand to Acquire Metabasis for Cash and Contingent Value Rights  -  ‎Oct 27, 2009‎
Ligand has agreed to spend a minimum of $7 million on Metabasis programs over the 30 months following closing, unless both the glucagon and TRß programs ... Reuters

To Eat Less, Your Body May Want You to Eat Slowly  -  ‎Nov 9, 2009‎
...they showed higher blood levels of two hormones -- peptide YY (PYY) and glucagon-like peptide 1 (GLP-1) -- for roughly three hours after the meal. ... ABC News

Lecture Series Named For Indiana Life Sciences Leader  -  ‎Nov 13, 2009‎
The company is also developing a glucagon analog for acute treatment of severe hypoglycemia. It was founded in 2005 and is located in Carmel, Indiana. ... Inside INdiana Business (press release)

Hormone Deficiency Linked to Impaired Glucose Metabolism Mice lacking ...  -  ‎Oct 19, 2009‎
Noting that dipeptidyl peptidases (DPPs) such as DPP4 have been shown to cleave and inactivate gastrointestinal hormones such as glucagon-like peptide 1 ... ModernMedicine

Health Matters : What is Pancreatitis ?  -  ‎Nov 13, 2009‎
Islands of cells in the pancreas produce the hormones insulin and glucagon. These hormones are critical for the metabolism of carbohydrates and fats. ... PR-Inside.com (Pressemitteilung)

Hypoglycemia Education - A Vital Weapon in the Battle to Conquer Diabetes  -  ‎Nov 12, 2009‎
...administer oral carbohydrate or injectable glucagon can quickly resolve a hypoglycemic episode, before requiring paramedic help or hospital admission. ... PR Newswire (press release)

REG-Lilly (Eli) & Co: STATEMENT ON FDA'S BYETTA (EXENATIDE) INJECTION UPDATE  -  ‎Nov 2, 2009‎
BYETTA exhibits many of the same effects as the human incretin hormone glucagon-like peptide-1 (GLP-1). GLP-1 improves blood sugar after food intake through ... Reuters

Data Demonstrate That GATTEX (Teduglutide) Improves Lean Body Mass, Mineral ...  -  ‎Oct 26, 2009‎
About GATTEX (teduglutide) GATTEX is the brand name for teduglutide, a proprietary analog of naturally occurring human glucagon-like peptide 2 (GLP-2), ... Reuters

Preparation, safety key to winter workouts  -  ‎Nov 11, 2009‎
..."Blood sugar and glucagon are needed to produce energy," Weber said. "You need to be able to shiver which requires increased energy. ... TheNewsTribune.com

De-stress from diabetes  -  ‎Nov 7, 2009‎
This includes cortisol and adrenaline (from the adrenal glands), glucagon and growth hormone. Stress tends to increase the levels of the second set of ... Hindu

Gastric bypass: Is it a diabetes fix?  -  ‎Oct 26, 2009‎
...the hormone that stimulates hunger, and elevates levels of peptide YY and glucagon-like peptide-1, both of which act as appetite suppressants. ... Los Angeles Times

Dangers from Without and Within  -  ‎Nov 7, 2009‎
Insulin acts to modulate this along with glucagon. Insulin blocks the liver production of glucose while glucagon promotes the production of glucose. ... A Sweet Life, the source for the healthy diabetic (blog)

A tale of calories  -  ‎Nov 11, 2009‎
It turned out that the slow eaters had higher concentrations of peptide YY and a glucagon-like peptide — the two hormones that the gut makes and sends to ... Philippine Star

Effects of Liraglutide in the Treatment of Obesity: A Randomised, Double-Blind ...  -  ‎Oct 23, 2009‎
Study Question: Liraglutide, a glucagon-like peptide-1 (GLP-1) administered subcutaneously once daily, is effective in diabetes and induces weight loss. ... Cardiosource

OTC: Emisphere Technologies Announces Financial and Operational Results for ...  -  ‎Nov 9, 2009‎
Oral Glucagon-Like Peptide-1 (GLP-1): o On September 8, 2009 , Emisphere Technologies announced that an article published in the September 2009 issue of ... RTT News (press release)

Amylin Pharmaceuticals Inc. Reports Operating Results (10-Q)  -  ‎Nov 5, 2009‎
BYETTA is the first and only approved medicine in a new class of compounds called glucagon-like peptide-1, or GLP-1, receptor agonists. ... GuruFocus.com

Tomatoes could help shed weight  -  ‎Nov 5, 2009‎
Previous studies on that gut hormones, such as peptide YY (PYY) and glucagon-like peptide (GLP-1), has shown that their release after a meal acts on the ... Rediff

Hi-maize Resistant Starch Shown to Help Adults Eat Less Food over 24 Hours  -  ‎Nov 12, 2009‎
...on the genes that make satiety hormones glucagon-like peptide-1 (GLP-1) and peptide YY (PYY), and that these hormones remained elevated for 20+ hours. ... Earthtimes (press release)

Children adapt to Type 1 diabetes  -  ‎Oct 23, 2009‎
They can, however, give a glucagon shot in an emergency; this happens when blood sugar dips so low the child can't drink or eat. ... Los Angeles Times

Ipsen's partner Roche announces positive results from Phase III diabetes study  -  ‎Oct 30, 2009‎
Phase III clinical study using taspoglutide, the first human once weekly glucagon-like peptide-1 or GLP-1 analogue originating from Ipsen's research. ... Trading Markets (press release)

Onglyza: new for diabetes  -  ‎Oct 26, 2009‎
These drugs prevent the breakdown of incretins, which stimulates insulin secretion and inhibits glucagon release; consequently, blood glucose levels fall. ... Healthcare Republic

Optimal Insulin Treatment in Type 2 Diabetes  -  ‎Oct 22, 2009‎
Long-term data are lacking for dipeptidyl peptidase-4 inhibitors, which increase endogenous levels of glucagon-like peptide 1 (GLP-1), and for exenatide and ... New England Journal of Medicine (subscription)

AACE updates guidelines for GH use, dosing and diagnosis of GH deficiency  -  ‎Nov 6, 2009‎
The arginine + GH-releasing hormone stimulation test, glucagon test and the arginine test alone are acceptable alternatives. The authors of the guidelines ... Endocrine Today

'Silent killer' has variety of symptoms, causes  -  ‎Nov 1, 2009‎
The endocrine function involves the production of the hormones insulin and glucagon to maintain the proper levels of sugar in the blood. ... Aiken Standard (subscription)

Health Matters : Insulinoma ?  -  ‎Nov 7, 2009‎
Specialized clusters of cells in the pancreas, called islets of Langerhans, secrete insulin and glucagon directly in to the blood stream. ... PR-Inside.com (Pressemitteilung)

Cardiovascular connections: two-way street between heart and health  -  ‎Nov 4, 2009‎
It also makes insulin, a hormone needed to usher blood sugar into muscle cells, and glucagon, which tells the liver to release stored glucose when blood ... Sun-Sentinel.com

New drug for type 2 diabetes  -  ‎Oct 29, 2009‎
Also, pancreatic glucagon secretion is lowered by GLP-1. Saxagliptin inhibits DPP4, thereby slowing down the inactivation of the incretin hormones, ... Clinical Advisor

Alkermes 'Pops' Back in Gear: Cash Aplenty to Fuel Licensing  -  ‎Nov 6, 2009‎
Hanging over Byetta LAR's PDUFA date is a mixed panel vote in April for potential competitor liraglutide (Novo Nordisk), another glucagon-like peptide-1 ... Therapeutics Daily (press release) (registration)

Metabolic disease: Dual benefit of bile acid receptor agonist  -  ‎Oct 30, 2009‎
...as these cells secrete the incretin glucagon-like peptide 1 (GLP1), which increases insulin secretion in response to elevated blood glucose levels. ... Nature.com (subscription)

Liraglutide bests Xenical at cutting weight, blood pressure  -  ‎Oct 23, 2009‎
Novo Nordisk has had to be patient with liraglutide, a glucagon-Like Peptide-1 (GLP-1) analogue that inhibits appetite and stimulates the release of insulin ... FierceBiotech

New Report Just Published GPCRs: Dawn of a New Era?  -  ‎Oct 23, 2009‎
Drug Candidates for Glucagon and Glucagon-Like Peptide-1 Receptors Table 4.38. Launched Drugs Targeting the Gonadotropin-Releasing Hormone Receptor Table ... Live-PR.com (Pressemitteilung)

NPS Reports Two Teduglutide Abstracts Accepted for Presentation at American ...  -  ‎Oct 21, 2009‎
GATTEX (teduglutide) is a proprietary analog of human glucagon-like peptide 2 that stimulates the repair and regeneration of cells lining the intestine. ... Earthtimes (press release)

매ì?¼ê²½ì œ 홈 > 뉴스센터 > êµ­ì œ  -  ‎Oct 22, 2009‎
...[1]About Victoza(R)Victoza(R) is a human glucagon-like peptide-1 (GLP-1) analogue developed for the treatment of type 2 diabetes. Victoza(R) lowers blood ... 매일경제

Glucagon - Tests, Test Results & Diagnosis - NY Times Health Informati...  -  Sep 2, 2008
A glucagon test measures the amount of a hormone called glucagon in your blood. Glucagon is produced by cells in the pancreas. It helps control blood sugar ... New York Times

Is secretion of glucagon-like peptide-1 reduced in type 2 diabetes...  -  Mar 15, 2008
Postprandial augmentation of insulin secretion by gastrointestinal peptide hormones—the so-called 'incretin effect'—is reduced in patients with type 2 ... Nature.com

… /carbohydrate mixtures on postprandial glucagon and insulin...  -  Oct 16, 2006
Postprandial plasma glucose, glucagon, insulin and amino acids were determined over 2 h ... Gluten protein hydrolysate induced the lowest glucagon response. ... Nature.com

New Diabetes Drug Works Well in Trial  -  Sep 29, 2008
The drug, liraglutide, is a laboratory-made version of glucagon-like peptide-1 (GLP-1), ... "Then it also promotes glucagon release from the pancreas. ... Washington Post

GLP-1 and Appetite Responses to a Meal in Lean and Overweight …  -  Feb 16, 2007
We prospectively investigated the effects of exercise on glucagon-like ... Glucagon-like peptide-1 (GLP-1) is produced primarily by the intestine in ... Nature.com

Glucagon-like peptide-1 (7–36) amide response to low versus high …  -  Nov 14, 2005
Contributors: JEM was responsible for the experimental design, subject recruitment, data collection and analysis, biochemical analysis and writing of the ... Nature.com

The Role of Glucagon in Postprandial Hyperglycemia—The Jury's Still …  -  Jun 12, 2007
Address all correspondence and requests for reprints to: Dr. Carla J. Greenbaum, Benaroya Research Institute, 1201 9th Avenue, Seattle, Washington 98101. ... Journal of Clinical Endocrinology and...

Roche to market Ipsen diabetes drug, pay Ipsen at least 59 mln eur - ...  -  Jul 19, 2006
BIM 51077, an analogue of peptide hormone GLP-1 (Glucagon Like Peptide-1), controls insulin secretion in response to elevated blood glucose levels. Forbes

A new drug can improve treatment by increasing insulin sensivity and ...  -  Sep 15, 2008
If the level is too low, glucagon is produced and this restricts the production of ... The incretins are the glucagon-like peptide GLP-1 and the gastric ... Times Online

Liraglutide, a Once-daily Human Glucagon-like Peptide-1 Analog, …  -  May 23, 2006
Correspondence: Kirsten Raun Diabetes Pharmacology, Novo Nordisk A/S, Novo Nordisk Park, DK-2760 Maaloev, Denmark. E-mail: kira@novonordisk.com ... Nature.com

glucagon - MSN Health & Fitness - Medications  -  Jul 13, 2005
Familiarize yourself with the directions included in the glucagon product before you have to use it. This information handout is not intended to replace the ... MSN Health & Fitness

Digital Chosunilbo (English Edition) : Daily News in English About...  -  Aug 27, 2008
They discovered that leptin removed glucagon, a hormone involved in carbohydrate metabolism, and thus lowered the blood sugar level. ... 조선�보 - 조선�보(�문�)

Clinical Results Of VLD-Glucagon For Nocturnal Hypoglycemia Are …  -  Jun 25, 2007
DIO-901, a Very Low Dose Glucagon (VLD(TM)-Glucagon), can delay or prevent nocturnal hypoglycemia and reduce the number and duration of hypoglycemic ... emaxhealth.com

A human -cell line for transplantation therapy to control type 1...  -  Sep 25, 2005
...(i,j) Glucagon-staining (green) of the pancreas. Reverted NAKT-15 cells in the kidney capsule were immunopositive for insulin, whereas the pancreas and ... Nature.com

What Are The Meanings and Significance Of These Terms Related To …  -  Jan 11, 2008
Question: What are the meanings and significance of these terms related to diabetes: 'beta cells,' 'islets,' 'glucagon,' and 'amylin'? ... ABC News

Glucagon :: Diabetes Self-Management  -  May 18, 2006
Diabetes Self-Management provides a wealth of information from blogs to recipes to articles to help manage your health. These articles cover a wide range of ... Diabetes Self Management

… Announces a License Agreement for its Glucagon-Like Peptide-1 (GLP...  -  Sep 26, 2007
...under which OctoPlus NV (Euronext:OCTO) has acquired exclusive worldwide rights to develop and commercialize Theratechnologies' Glucagon-like Peptide-1 ... marketwire.com

Learn about Glucagon from Consumer Reports Health.  -  Jan 4, 2005
Glucagon is a hormone produced in the pancreas. Glucagon is used to raise very low blood sugar. Glucagon is also used in diagnostic testing of the stomach ... consumerreports.org

Apparent thermogenic effect of injected glucagon is not due to a...  -  Apr 1, 2006
To examine the significance of brown adipose tissue for the thermogenic response to glucagon, we injected glucagon intraperitoneally into rats (that have ... AJP-Regul Integr Comp Physiology...

GLUCAGON (Injection route) - GLOO-ka-gon.(Drug overview)  -  May 1, 2007
Glucagon belongs to the group of medicines called hormones. It is an emergency medicine used to treat severe hypoglycemia (low blood sugar) in patients with ... Free with registration - USP DI-Volume II, Advice for the... - AccessMyLibrary.com

Diabetes Therapy; Glucagon receptor antagonists lower glucose levels...  -  Jan 3, 2005
2005 JAN 3 - (NewsRx.com & NewsRx.net) -- Peptidyl and non-peptidyl glucagon receptor antagonists bind to hepatic glucagon receptors and lower glucose ... Pay-Per-View - Diabetes Week - Factiva, from Dow Jones

How to give glucagon  -  Oct 3, 2008
This information is for people who may need to give a person with diabetes an injection of glucagon during a low blood sugar emergency. ... MSN Health & Fitness

Meal-stimulated glucagon release is associated with postprandial...  -  May 14, 2007
Sven Pörksen * , Lotte B. Nielsen, Anne Kaas, Mirjana Kocova, Francesco Chiarelli, Cathrine rskov, Jens J. Holst, Kenneth B. Ploug, Philip Hougaard, ... Journal of Clinical Endocrinology and...

… muscle in the calorigenic response to glucagon of cold-acclimated ...  -  Apr 1, 2006
The site of the calorigenesis observed in birds after glucagon was sought in ... Glucagon-induced calorigenesis (GIC) was estimated at 25 degrees C after a ... AJP-Regul Integr Comp Physiology...

Merck Research Laboratories; Glucagon receptor antagonists lower …  -  Jan 5, 2005
2005 JAN 5 - (NewsRx.com & NewsRx.net) -- Peptidyl and non-peptidyl glucagon receptor antagonists bind to hepatic glucagon receptors and lower glucose ... Pay-Per-View - Biotech Week - Factiva, from Dow Jones

R-type Ca 2+ -channel-evoked CICR regulates glucose-induced …  -  Mar 18, 2007
In addition to insulin-producing -cells and glucagon-secreting -cells, ... Somatostatin is a powerful inhibitor of insulin and glucagon secretion 2 . ... Nature.com

Article: Appetite control: A sweet result.(glucagon-like peptide-1...  -  Jul 26, 2008
Article: Appetite control: A sweet result.(glucagon-like peptide-1 and how we perceive sweetness) ... find The Economist (US) articles. Pay-Per-View - The Economist - HighBeam Research

Diabetes Therapy; Glucagon receptor antagonists lower glucose levels...  -  Jan 7, 2005
2005 JAN 7 - (NewsRx.com & NewsRx.net) -- Peptidyl and non-peptidyl glucagon receptor antagonists bind to hepatic glucagon receptors and lower glucose ... Pay-Per-View - Drug Week - Factiva, from Dow Jones

… Statutes - 53A-11-603. Administration of glucagon — Training of...  -  Jun 7, 2006
53A-11-603 . Administration of glucagon — Training of volunteer school personnel — Authority to use glucagon — Immunity from liability. ... Pay-Per-View - Utah Statutes - Loislaw

… Promising Preclinical Results with Its Novel Glucagon Antagonist...  -  Sep 17, 2007
Glucagon is a hormone produced by the pancreas that stimulates the liver to ... Glucagon receptor antagonists are designed to lower glucose levels by ... Genetic Engineering News - Genetic Engineering News (press release)

Convalescent Mulroney reportedly 'despondent'  -  Jun 9, 2005
...a large gland responsible for secreting digestive enzymes into the small intestine, as well as pumping insulin and glucagon into the bloodstream. ... CTV.ca

Glucagon Suppression of Ghrelin Secretion is exerted at Hypothalamus-...  -  Jun 13, 2006
AM Arafat * , FH Perschel, B. Otto, MO Weickert, H. Rochlitz, C. Schöfl, J. Spranger, M. Möhlig, and AFH Pfeiffer. * To whom correspondence should be ... Journal of Clinical Endocrinology and...

Evidence for an Augmented Glucagon Dependence of Hepatic Glucose …  -  Feb 15, 2007
Address correspondence and requests for reprints to: Ulrich Keller, MD, Division of Endocrinology and Metabolism, Kantonsspital Basel, CH-4031 Basel, ... Journal of Clinical Endocrinology and...

glucagon -- Britannica Online Encyclopedia  -  Jun 5, 2008
Britannica online encyclopedia article on glucagon: a pancreatic hormone produced by cells in the islets of Langerhans. Glucagon, a protein of low molecular ... Subscription - Encyclopedia Britannica

Gender difference in the glucagon response to glucopenic stress in...  -  May 1, 2005
A gender difference in the glucagon response to insulin-induced hypoglycemia was previously demonstrated in humans. Whether this reflects a gender ... AJP-Regul Integr Comp Physiology...

Diabetes: glucagon injections.  -  May 24, 2006
Glucagon is a hormone made in the pancreas, like insulin. However, it has the opposite effect of insulin. It raises the blood sugar level rather than ... $4.95 - Clinical Reference Systems - ECNext

Wales News Surgery 'cure' for diabetes  -  Jun 4, 2007
...at Swansea NHS Trust, will focus its research efforts on a protein known as Glucagon Like Peptide 1 (GLP-1), which is produced in the small intestine. ... WalesOnline

Diabetes Therapy; Glucagon-like peptide derivatives show promise for ...  -  Jun 20, 2005
2005 JUN 20 - (NewsRx.com) -- Researchers review glucagon-like peptide 1 and its derivatives in the treatment of diabetes in a recent issue of Regulatory ... Pay-Per-View - Health & Medicine Week - Factiva, from Dow Jones

Lipolytic and metabolic response to glucagon in fasting king penguins:...  -  Aug 1, 2008
This study aims to determine how glucagon intervenes in the regulation of fuel metabolism, especially lipolysis, at two stages of a spontaneous long-term ... AJP-Regul Integr Comp Physiology...

Diabetes: glucagon injections.(Pediatric Advisor 2006)(Drug overview)  -  Nov 1, 2006
Glucagon is a hormone made in the pancreas, like insulin. However, it has the opposite effect of insulin. It raises the blood sugar level rather than ... $4.95 - Clinical Reference Systems - ECNext

Anesiva licenses drug injection system to Particle Therapeutics  -  Aug 30, 2007
Particle, based in Oxford, England, will use the injection system for glucagon, a hormone used in treating diabetic hypoglycemia. ... Bizjournals.com

Diabetes Therapy; Glucagon-like peptide-1 on benefits diabetic...  -  Jan 23, 2005
2005 JAN 23 - (NewsRx.com & NewsRx.net) -- Glucagon-like peptide-1 on improves endothelial function in type 2 diabetes patients with stable coronary artery ... Pay-Per-View - Heart Disease Weekly - Factiva, from Dow Jones

… hormone, cortisol, and insulin responses to glucagon injection in...  -  Sep 1, 2008
We performed glucagon stimulation tests in 59 normally growing siblings of ... There was a significant correlation between age and glucagon- stimulated ... Journal of Clinical Endocrinology and...

Diabetes Pathogenesis; Glucagon works to induce ERK 1/2 …  -  Apr 12, 2006
According to recent research from the United States, "Glucagon, a major insulin ... Inappropriate increases in serum glucagon play a critical role in the ... Pay-Per-View - Life Science Weekly - Factiva, from Dow Jones

… oscillations in the secretion of insulin and glucagon to the...  -  Jul 1, 2007
Influences of the central nervous system on these ultradian glucagon and insulin ... Significant glucagon and insulin peaks were determined by the peak ... Journal of Clinical Endocrinology and...

Glucagon Receptor Recycling: Role of Carboxyl Terminus, -arrestins,...  -  Aug 30, 2008
Glucagon receptor (GR) activity and expression are altered in several diseases, including Type 2 diabetes. Previously, we investigated the mechanism of GR ... AJP - Cell Physiology (subscription)

… Pathogenesis; Paradoxical stimulation of glucagon secretion by...  -  Oct 3, 2006
According to recent research from Sweden, "Hypersecretion of glucagon contributes to the ... To clarify the underlying mechanism, glucose-regulated glucagon ... Pay-Per-View - Life Science Weekly - Factiva, from Dow Jones

Diabetic kids to go to DC  -  Jun 6, 2005
The kit also includes glucagon, which is used if Anthony were to go unconscious, ... Glucagon is a hormone used to release stored sugar in the body. ... $3.50 - The Sun - NewsBank

Diabetes: glucagon injections.(Pediatric Advisor 2007)  -  May 31, 2007
Glucagon is a hormone made in the pancreas, like insulin. However, it has the opposite effect of insulin. It raises the blood sugar level rather than ... $4.95 - Clinical Reference Systems - ECNext

Glucagon .  -  Nov 23, 2006
...contends that is not the case, noting that a parent-designated adult who is properly trained in glucagon administration can give such treatment. ... Fress Press - Google News Archive

… Endocrine-Disrupting Chemicals Impair Glucagon-Releasing Alpha...  -  May 16, 2005
Glucagon is released by alpha cells in the pancreas. ... This suggests that glucagon levels in the bloodstream could be affected by low levels of BPA and ... newswise.com

Pentagastrin and Glucagon Stimulate Serum Somatostatin-Like …  -  Sep 1, 2008
Address all correspondence and requests for reprints to: Dr. Sol Epstein, Clinical Research Center, Indiana University Medical Center, 1100 West Michigan ... Journal of Clinical Endocrinology and...

Glucagon .  -  Nov 23, 2006
...contends that is not the case, noting that a parent-designated adult who is properly trained in glucagon administration can give such treatment. ... Cheney Free Press - Google News Archive

… as Determinants of Glucose, Insulin, and Glucagon Responses to...  -  Sep 1, 2005
The effect of human β-endorphin on plasma glucose, insulin, and glucagon concentrations was studied in patients with noninsulin-dependent diabetes mellitus ... Journal of Clinical Endocrinology and...

… Clinical Results of VLD(TM)-Glucagon for Nocturnal Hypoglycemia at...  -  Jun 22, 2007
SAN FRANCISCO , June 22 /PRNewswire/ -- DiObex, Inc., a privately-held biopharmaceutical company focused on the development of therapeutics to treat ... Genetic Engineering News - Genetic Engineering News (press release)

Gene Oppositely Controlled By Dietary Protein, Sugar  -  Apr 10, 2008
When blood glucose is low, glucagon is secreted by other pancreatic cells, ... The antagonism between insulin and glucagon is not strict, the researchers ... Medical News Today - Medical News Today (press release)

Diabetes Therapy; Recent findings in diabetes therapy described  -  Apr 4, 2005
Study 2: Peptidyl and non-peptidyl glucagon receptor antagonists bind to hepatic ... "Glucagon receptor antagonists have been actively pursued as potential ... Pay-Per-View - Proteomics Weekly - Factiva, from Dow Jones

… with Altered Plasma Insulin and Glucagon: Similarity to Effects of...  -  Jun 1, 2007
Fasting plasma glucagon concentrations were unaltered in AGS, but suppression of the hormone after oral glucose was greater and more prolonged relative to ... Journal of Clinical Endocrinology and...

Discovery Of Glucagon Secretion Mechanism May Lead To Improved …  -  Jan 14, 2006
A University of Toronto research team directed by Professor Qinghua Wang has discovered a mechanism for secretion of the hormone glucagon, ... Medical News Today - Medical News Today (press release)

Potentiation of Glucagon Secretion by Serotonin Antagonists in Man  -  Mar 1, 2005
Presented at the 11th Annual Meeting of the European Association for the Study of Diabetes, September 4, 1975, Munich, Federal Republic of Germany. ... Journal of Clinical Endocrinology and...

Gene oppositely controlled by dietary protein, sugar  -  Apr 8, 2008
When blood glucose is low, glucagon is secreted by other pancreatic cells, ... The antagonism between insulin and glucagon is not strict, the researchers ... PhysOrg.com

… ; Arginine vasopressin plays role in diabetic increase in glucagon ...  -  Feb 1, 2005
Both glucagon and AVP were determined in the effluent of the perfused pancreas ... Both normal and diabetic rats had similar basal glucagon secretion," ... Pay-Per-View - Science Letter - Factiva, from Dow Jones

Endocrinology; Prohormone convertase studied, role in glucagon …  -  Mar 21, 2005
..."Cotransfection studies in GH4C1 cells show significant amounts of glucagon production by PC2 along with some glicentin, glicentin-related ... Pay-Per-View - Health & Medicine Week - Factiva, from Dow Jones

DiObex Receives Fast-Track Status From FDA for VLD-Glucagon.  -  Sep 28, 2005
SAN FRANCISCO, Sept. 28 /PRNewswire/ -- DiObex, Inc., a biotechnology company developing therapeutics for the treatment of metabolic diseases, ... $4.95 - PR Newswire - ECNext

… ; Arginine vasopressin plays role in diabetic increase in glucagon ...  -  Feb 5, 2005
Both glucagon and AVP were determined in the effluent of the perfused pancreas ... Both normal and diabetic rats had similar basal glucagon secretion," ... Pay-Per-View - Obesity, Fitness & Wellness Week - Factiva, from Dow Jones

… ; Arginine vasopressin plays role in diabetic increase in glucagon ...  -  Feb 4, 2005
Both glucagon and AVP were determined in the effluent of the perfused pancreas ... Both normal and diabetic rats had similar basal glucagon secretion," ... Pay-Per-View - Drug Week - Factiva, from Dow Jones

… ; Arginine vasopressin plays role in diabetic increase in glucagon ...  -  Feb 2, 2005
Both glucagon and AVP were determined in the effluent of the perfused pancreas ... Both normal and diabetic rats had similar basal glucagon secretion," ... Pay-Per-View - Biotech Week - Factiva, from Dow Jones

Endocrinology; Prohormone convertase studied, role in glucagon …  -  Mar 26, 2005
..."Cotransfection studies in GH4C1 cells show significant amounts of glucagon production by PC2 along with some glicentin, glicentin-related ... Pay-Per-View - Obesity, Fitness & Wellness Week - Factiva, from Dow Jones

… ; Arginine vasopressin plays role in diabetic increase in glucagon ...  -  Jan 31, 2005
Both glucagon and AVP were determined in the effluent of the perfused pancreas ... Both normal and diabetic rats had similar basal glucagon secretion," ... Pay-Per-View - Proteomics Weekly - Factiva, from Dow Jones

Glucagon Secretion Mechanism Discovered  -  Jan 31, 2006
Researchers at the University of Toronto have discovered a mechanism for secretion of the hormone glucagon, which could facilitate the development of new ... Diabetes In Control

… of Insulin on Secretion of Insulin, Glucagon, Gastric Inhibitory...  -  Nov 1, 2005
The direct effect of insulin on the secretion of insulin (as measured by C-peptide), glucagon, gastric inhibitory polypeptide, and gastrin was studied in ... Journal of Clinical Endocrinology and...

… -Track Status From FDA for VLD-Glucagon. - PR Newswire | HighBeam …  -  Sep 28, 2005
DiObex Receives Fast-Track Status From FDA for VLD-Glucagon. from PR Newswire. Highbeam Research – FREE Trial. Pay-Per-View - PR Newswire - HighBeam Research

Diabetics lobby for lifesaving-injection bill  -  Mar 24, 2007
Insulin is used to lower blood sugar, while glucagon is used to raise it when ... According to the association, there have been cases where glucagon was not ... Salem News - The Salem News

Insulin; Fast track status received for VLD-Glucagon  -  Oct 24, 2005
2005 OCT 24 - (NewsRx.com) -- DiObex, Inc., a biotechnology company developing therapeutics for the treatment of metabolic diseases, announced that the US ... Pay-Per-View - Biotech Business Week - Factiva, from Dow Jones

Insulin; Fast track status received for VLD-Glucagon  -  Oct 29, 2005
2005 OCT 29 - (NewsRx.com) -- DiObex, Inc., a biotechnology company developing therapeutics for the treatment of metabolic diseases, announced that the US ... Pay-Per-View - Obesity, Fitness & Wellness Week - Factiva, from Dow Jones

Insulin; Fast track status received for VLD-Glucagon  -  Oct 25, 2005
2005 OCT 25 - (NewsRx.com) -- DiObex, Inc., a biotechnology company developing therapeutics for the treatment of metabolic diseases, announced that the US ... Pay-Per-View - Science Letter - Factiva, from Dow Jones

How to take Glucagon from Consumer Reports Health.  -  Jan 4, 2005
...tell your doctor and pharmacist if you are allergic to glucagon, any other drugs, or beef or pork products. tell your doctor and pharmacist what ... consumerreports.org

Key Regulator of Blood Glucose Levels Discovered  -  Sep 7, 2005
At night, however, the pancreas releases glucagon into the bloodstream, ... This increase in glucagon turns on the TORC2 switch and allows the liver to make ... RedOrbit

Cheney Schools Seek To Resolve Glucagon Issue .  -  Nov 23, 2006
Cheney schools seek to resolve glucagon issue . Staff Reporter . As parents of an eighth-grade student with type 1 diabetes, Cheney School District parents ... Cheney Free Press - Google News Archive

… Associated with Reduced Insulin and Glucagon Secretion and...  -  Dec 1, 2006
Also, the glucagon response to arginine was reduced in the athletes (58.8 ± 6.7 vs. ... Abbreviations: ACR, Acute C-peptide response; AGR, acute glucagon ... Journal of Clinical Endocrinology and...

… intrinsic heart rate in mice independent of the glucagon-like...  -  Jun 9, 2006
Oxyntomodulin (OXM), a postprandially released intestinal hormone, inhibits food intake via the glucagon-like peptide-1 receptor (GLP-1R). ... AJP-Regul Integr Comp Physiology...

Be Aware of Hypoglycemia Unawareness  -  Jul 20, 2006
Glucagon should be given based on a child's symptoms, not his blood sugar level. ... Inject glucagon instead. On the other hand, if your child's blood ... Diabetes Self Management

Emergency warning signs  -  May 1, 2006
Your doctor may want you to have a glucagon kit for emergencies. Consult your doctor about who should learn how to inject glucagon in the event that you ... Daily Advance - The Daily Advance

Diabetes Therapy; Role of glucagon-like peptide 1 in treatment of …  -  Apr 26, 2005
2005 APR 26 - (NewsRx.com) -- Researchers review the role of glucagon-like peptide 1 in the treatment of diabetes in a recent issue of Hormone and Metabolic ... Pay-Per-View - Science Letter - Factiva, from Dow Jones

… Phase 1 Study of ISIS 325568 Targeting Glucagon Receptor to Treat ...  -  Sep 4, 2007
Isis Initiates Phase 1 Study of ISIS 325568 Targeting Glucagon Receptor to Treat Type 2 Diabetes. from PR Newswire. Highbeam Research – FREE Trial. Pay-Per-View - PR Newswire - HighBeam Research

… -blocker toxicity treated with vasopressin or glucagon shows no...  -  Apr 4, 2006
Each pig was randomly assigned to receive either vasopressin or glucagon after the ... The glucagon group received a 0.05-mg/kg bolus followed by continuous ... Pay-Per-View - Life Science Weekly - Factiva, from Dow Jones

… of EDCs: low doses can impair glucagon secretion.(Environews:...  -  Aug 1, 2005
These cells secrete glucagon and insulin, respectively, hormones that regulate blood ... Glucagon regulates functions in fat tissue and in the liver, brain, ... $4.95 - Environmental Health Perspectives - ECNext

Ipsen: Roche Moves Investigational Diabetes Drug, Taspoglutide, into ...  -  Jun 10, 2008
1,2,) Taspoglutide, the first human once weekly glucagon-like peptide-1 (GLP-1) analogue originating from Ipsen's Research, is a compound similar to the ... RedOrbit

… Clinical Results of VLD(TM)-Glucagon for Nocturnal Hypoglycemia at...  -  Jun 22, 2007
DiObex Announces Clinical Results of VLD(TM)-Glucagon for Nocturnal Hypoglycemia at the 67th Annual Scientific Sessions of the American Diabetes ... Pay-Per-View - PR Newswire - HighBeam Research

Dosing Convenience Mandates The Pipeline Of Glucagon-like Peptide-1 …  -  Feb 6, 2006
Twice-daily injection is the benchmark set by exenatide, the first GLP-1 analog launched in the US by Lilly in June 2005 and half-year sales of US$ 74.6 mln ... Medical News Today - Medical News Today (press release)

Diabetes Therapy; Role of glucagon-like peptide 1 in treatment of …  -  Apr 29, 2005
2005 APR 29 - (NewsRx.com) -- Researchers review the role of glucagon-like peptide 1 in the treatment of diabetes in a recent issue of Hormone and Metabolic ... Pay-Per-View - Drug Week - Factiva, from Dow Jones

… 5-412. Definition — parent-designated adult — administration of...  -  Aug 5, 2005
...(3) A parent-designated adult may administer glucagon to a diabetic student ... The glucagon must be provided by the parent, an individual who has executed ... Pay-Per-View - Montana Statutes - Loislaw

Endocrinology; Glucagon receptor gene ablation raised fetal lethality...  -  Oct 17, 2006
2006 OCT 17 - (NewsRx.com) -- Ablation of the glucagon receptor gene increases fetal lethality and produces alterations in islet development and maturation. ... Pay-Per-View - Life Science Weekly - Factiva, from Dow Jones

… nutrients potentiate the intestinotrophic action of glucagon-like...  -  Sep 29, 2008
Glucagon-like peptide-2 (GLP-2) is a nutrient-dependent, intestinotrophic hormone derived from posttranslational processing of proglucagon in the distal ... AJP-Regul Integr Comp Physiology...

Higher fasting plasma concentrations of glucagon-like peptide 1 are …  -  Sep 1, 2007
Background: Glucagon-like peptide 1 (GLP-1) is a gut hormone that decreases appetite and promotes satiety. Its role in energy metabolism regulation is still ... Am J Clin Nutr (subscription)

Cheney schools seek to resolve glucagon issue .  -  Nov 23, 2006
As parents of an eighth-grade student with type 1 diabetes, Cheney School District parents Brent and anne-jeannette Dickson are understandably concerned ... Fress Press - Google News Archive

… Availability of doses of epinephrine and glucagon to trained...  -  Mar 1, 2007
The person may possess and administer glucagon to the student for whom the glucagon is prescribed, if the student is suffering a severe hypoglycemic ... Pay-Per-View - Oregon Statutes - Loislaw

Exogenous Glucagon-Like Peptide-2 (GLP-2) Augments GLP-2 Receptor …  -  May 1, 2008
Exogenous Glucagon-Like Peptide-2 (GLP-2) Augments GLP-2 Receptor mRNA and Maintains Proglucagon mRNA Levels in Resected Rats ... find JPEN, ... Pay-Per-View - JPEN, Journal of Parenteral and Enteral... - HighBeam Research

Metabolism; Control of glucagon-like peptide secretion reviewed  -  Apr 4, 2005
2005 APR 4 - (NewsRx.com) -- Researchers review nutrient, neural, and endocrine control of glucagon-like peptide secretion in a recent issue of Hormone and ... Pay-Per-View - Diabetes Week - Factiva, from Dow Jones

Liraglutide Phase 2 Study Shows Increased Insulin Secretion And …  -  Jun 14, 2006
When glucose levels become too high, GLP-1 triggers the release of insulin from the pancreas(13) and decreases the secretion of glucagon,(14) a hormone that ... Medical News Today - Medical News Today (press release)

Brand Names/Synonyms:
Glucagon is also known by the following brand names and/or synonymsGlucagon precursor [Contains: Glicentin; Glicentin-related polypeptide;GRPP; Oxyntomodulin;OXY;OXM; Glucagon; Glucagon-like peptide 1;GLP-1; Glucagon-like peptide 1(7-37);GLP-1(7-37); Glucagon-like peptide 1(7-36);GLP-1(7-36); Glucagon-like peptide 2;GLP-2];Fragment; Glucagon (Eli Lilly); GlucaGen (Novo Nordisk)

Drug Category:
Glucagon is categorized under the following by the FDA: Antihypoglycemic Agents; glycogenolytic agents (68:22.12)

Dosage Forms:
KIT;POWDER FOR SOLUTION

Absorption:
Not Available

Interactions:
Not Available



Chemical IUPAC Name:
Human Glucagon





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