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HycamtinThis page contains recent news articles, when available, and an overview of Hycamtin but does not offer medical advice. You should contact your physician with regard to any health issues or concerns.Overview: Hycamtin (when available) Topotecan, a semi-synthetic derivative of camptothecin (a plant alkaloid obtained from the Camptotheca acuminata tree), is an anti-tumor drug with topoisomerase I-inhibitory activity similar to irinotecan. Topotecan interferes with the growth of cancer cells, which are eventually destroyed. Since the growth of normal cells may also be affected by the medicine, other effects may also occur. Unlike irinotecan, topotecan is found predominantly in the inactive carboxylate form at neutral pH and it is not a prodrug. For the treatment of metastatic carcinoma of the ovary and small cell lung cancer following the failure of first-line chemotherapy. Mechanism Of Action: Topotecan has the same mechanism of action as irinotecan. Topoisomerase I relieves torsional strain in DNA by inducing reversible single strand breaks. Topotecan binds to the topoisomerase I-DNA complex and prevents religation of these single strand breaks. The cytotoxicity of topotecan is thought to be due to double strand DNA damage produced during DNA synthesis when replication enzymes interact with the ternary complex formed by topotecan, topoisomerase I and DNA. Mammalian cells cannot efficiently repair these double strand breaks. News Articles on Topotecan Partial victory for Hycamtin after final 'yes' from NICE - Oct 28, 2009 The cost regulator for England and Wales has issued the final go-ahead for doctors to prescribe GlaxoSmithKline's Hycamtin on the National Health Service ... Pharma Times Unigene Licenses Phase III Oral Calcitonin Program to Tarsa Therapeutics - Oct 21, 2009 ...for pre-launch commercial development plans for Coreg ® , Hycamtin ® and Requip ® . He also led the business units that launched Requip and Avandia ® . ... PharmaLive.com (press release) … granted EU marketing approval for Hycamtin for cervical cancer - Dec 1, 2006 LONDON (AFX) - GlaxoSmithKline PLC said the European Medicines Agency (EMEA) has granted marketing authorisation for its Hycamtin product in combination ... Forbes GlaxoSmithKline's Hycamtin receives positive lung cancer opinion in … - Nov 24, 2005 LONDON (AFX) - GlaxoSmithKline PLC said its Hycamtin drug has received a positive opinion on lung cancer treatment from an EU regulatory committee that it ... Forbes GSK says US FDA accepts Hycamtin, Cisplatin combination application - Feb 17, 2006 PHILADELPHIA (AFX) - GlaxoSmithKline said its supplemental New Drug Application (sNDA) for Hycamtin (topotecan HCl) for Injection submitted on Dec 15, ... Forbes Glaxo's lung cancer treatment candidate Oral Hycamtin gets FDA... - Jun 13, 2007 NEW YORK (Thomson Financial) - GlaxoSmithKline PLC said yesterday the Food and Drug Administration granted its lung cancer treatment candidate Oral Hycamtin ... Forbes IV HYCAMTIN(R) Receives European Marketing Approval As Treatment … - Feb 2, 2006 GlaxoSmithKline (GSK) announced that the European Commission (EC) has granted Marketing Authorisation for HYCAMTIN(R) (topotecan powder for concentrate for ... Medical News Today - Medical News Today (press release) EU agency backs Glaxo's Hycamtin for lung cancer - Feb 4, 2008 LONDON, Feb 4 (Reuters) - GlaxoSmithKline Plc (GSK.L) said on Monday its capsule drug Hycamtin had been recommended for approval by the European Medicines ... Reuters … Announces Expanded Indication For Hycamtin(R) To Treat Cervical … - Jun 16, 2006 GlaxoSmithKline (NYSE: GSK) announced today that the US Food and Drug Administration (FDA) approved Hycamtin (topotecan HCl) in combination with cisplatin, ... Medical News Today - Medical News Today (press release) Oral Hycamtin Receives FDA Priority Review - Jun 13, 2007 The FDA has granted priority review to GlaxoSmithKline's NDA for oral Hycamtin (topotecan) capsules, a proposed treatment for relapsed small cell lung ... Facts and Comparisons GlaxoSmithKline announces Hycamtin® receives positive opinion in … - Nov 28, 2005 28 Nov 2005 - GlaxoSmithKline (GSK) announced that HYCAMTIN® (topotecan powder for concentration for solution for infusion) received positive opinion from ... chemie.de Hycamtin IV : User Ratings covering uses, effectiveness, interactions... - Oct 14, 2008 My 54 year old wonderful wife has been treated with this drug for 6 months and she has tolerated it very well, with no negative side effects. ... WebMD GSK's Hycamtin Approved For Lung Cancer Treatment - Oct 15, 2007 Hycamtin is the first FDA approved oral therapy will allow patients to receive treatment for relapsed small cell lung cancer. ... emaxhealth.com FDA Approves GSK's Hycamtin - Oct 17, 2007 GlaxoSmithKline (GSK) received approval from the FDA for Hycamtin capsules for the treatment of relapsed small cell lung cancer. ... FDA news - FDA news (subscription) Oral Hycamtin(R) Clinically Active in the Treatment of Small Cell and... - May 23, 2005 Results from two new, investigational Phase III clinical trials showed that oral Hycamtin(R) was clinically active in both small cell lung cancer (SCLC) and ... i-newswire.com Oral Hycamtin(R) Clinically Active in the Treatment of Small Cell and... - May 19, 2005 Results from two new, investigational Phase III clinical trials showed that oral Hycamtin(R) was clinically active in both small cell lung cancer (SCLC) and ... Medical News Today - Medical News Today (press release) … Announces Expanded Indication For Hycamtin(R) To Treat Cervical … - Jun 18, 2006 GlaxoSmithKline (NYSE: GSK) announced today that the US Food and Drug Administration (FDA) approved Hycamtin (topotecan HCl) in combination with cisplatin, ... Medical News Today - Medical News Today (press release) … Priority Review for Oral Formulation of HYCAMTIN(R) (topotecan) to... - Jun 15, 2007 GlaxoSmithKline (GSK) announced today that its new drug application (NDA) for ORAL HYCAMTIN(R) (topotecan) capsules, a treatment for relapsed small cell ... Cancer Focus BioNumerik begins Phase III ovarian cancer trials on new drug - Feb 7, 2008 The Phase III trial will compare Karenitecin with the chemotherapy drug topotecan (Hycamtin). Either drug can be given intravenously to advanced ovarian ... Bizjournals.com GSK Receives Approval For Hycamtin® (topotecan) Capsules For The … - Oct 21, 2007 GlaxoSmithKline [NYSE: GSK] announced approval by the US Food and Drug Administration (FDA) for oral Hycamtin ® (topotecan) capsules for the treatment of ... Medical News Today - Medical News Today (press release) Hycamtin® (topotecan HCl) Indication Expanded To Include Treatment Of... - Dec 8, 2006 GlaxoSmithKline plc announced today that the European Medicines Agency (EMEA) has granted Marketing Authorisation for HYCAMTIN® (topotecan HCl) in ... Medical News Today - Medical News Today (press release) … gets OK for new type of HIV drug; Hycamtin is approved; Labopharm ... - Oct 15, 2007 ...> The FDA has approved Merck's Isentress for HIV. This is a new type of drug, which prevents HIV from inserting its DNA into human DNA, stunting its ability ... FierceBiotech EU approves Glaxo drug Hycamtin for lung cancer - Feb 1, 2006 LONDON (Reuters) - The European Commission has given approval for GlaxoSmithKline Plc's Hycamtin drug to be used as a treatment for small cell lung cancer, ... RedOrbit … Studies Showed Oral Hycamtin(R) (Topotecan Hydrochloride) Clinicall... - May 17, 2005 ORLANDO, Fla., May 17 /PRNewswire-FirstCall/ -- Results from two new, investigational Phase III clinical trials showed that oral Hycamtin(R) was clinically ... Pay-Per-View - PR Newswire - HighBeam Research … Accepted By The FDA To Expand Use Of Hycamtin(R) In Combination … - Feb 18, 2006 GlaxoSmithKline (NYSE: GSK) today announced that the supplemental New Drug Application (sNDA) submitted to the US Food and Drug Administration (FDA) on ... Medical News Today - Medical News Today (press release) Drug combo zaps childhood cancer - Jul 12, 2007 Then the potent cancer killer topotecan (Hycamtin) was administered. When the researchers administered topotecan to the tumor-bearing mice three days after ... United Press International … Announces Expanded Indication for Hycamtin(R) to Treat Cervical … - Jun 15, 2006 GlaxoSmithKline Announces Expanded Indication for Hycamtin(R) to Treat Cervical Cancer in Combination Chemotherapy. from PR Newswire. Pay-Per-View - PR Newswire - HighBeam Research GSK's Hycamtin gets positive CHMP feedback.(GlaxoSmithKline AB)( … - Dec 5, 2005 UK drug major GlaxoSmithKline says that Hycamtin (topotecan powder), the firm's treatment for relapsed small-cell lung cancer, has received a positive ... $4.95 - Pharma Marketletter - ECNext EC OKs GSK's Hycamtin for relapsed SCLC.(European Commission)( … - Feb 6, 2006 UK drug major GlaxoSmithKline says that the European Commission has granted Marketing Authorization for Hycamtin (topotecan powder for concentrate for ... $4.95 - Pharma Marketletter - ECNext NIPPON KAYAKU APPLIES TO MAKE HYCAMTIN DRUG FOR OVARIAN … - May 14, 2007 TOKYO, May 14 Asia Pulse - Nippon Kayaku Co. (TSE:4272) applied Friday to the Ministry of Health to add treatment of ovarian cancer to the indications for ... Free with registration - AsiaPulse News - AccessMyLibrary.com ImClone taps ex-CTRC director for chief medical officer - Feb 15, 2005 Throughout his career, Rowinsky has worked toward the development of several drugs including paclitaxel (Taxol), docetaxel (Taxotere), topotecan (Hycamtin). ... San Antonio Business Journal Expanded US label for GSK's Hycamtin.(united states Food and Drug … - Jun 26, 2006 UK drug major GlaxoSmithKline says that the US Food and Drug Administration has approved its topoisomerase I inhibitor Hycamtin (topotecan) in combination ... Free with registration - Pharma Marketletter - AccessMyLibrary.com Hycamtin.(Priority review)(Brief article) - Aug 1, 2007 Topotecan (Hycamtin, GlaxoSmithKline) for the treatment of relapsed small cell lung cancer (SCLC) Free with registration - Formulary - AccessMyLibrary.com … Accepted by the FDA to Expand Use of Hycamtin(R) in Combination... - Feb 17, 2006 The sNDA seeks marketing approval for the new use of Hycamtin in combination ... Hycamtin is currently indicated for the treatment of metastatic carcinoma ... Pay-Per-View - PR Newswire - HighBeam Research Hycamtin Capsules Topotecan - Dec 1, 2007 Topotecan is a semisynthetic derivative of camptothecin; this antitumor agent acts as a topoisomerase I inhibitor, thus causing double-strand DNA damage ... Free with registration - Formulary - AccessMyLibrary.com topotecan GlaxoSmithKline clinical data (phase II) (NSCLC).(Brief... - Jul 18, 2005 A clinical trial of topotecan (HYCAMTIN) in the treatment of platinum and taxane refractory advanced nonsmall cell lung cancer (NSCLC) is under way in ... Pay-Per-View - R & D Focus Drug News - Factiva, from Dow Jones ALSO NOTED: Glaxo wins approval for Hycamtin; Affymax forecasts share... - Nov 30, 2006 ...> President Bush has signed a new law that expands the powers of federal authorities targeting the activities of animal rights groups. Report ... FierceBiotech Article: Hycamtin cleared.(RXs)(Brief article) - Chain Drug Review | ... - Nov 19, 2007 Hycamtin cleared.(RXs)(Brief article) ... find Chain Drug Review articles. GlaxoSmithKline PLC has received approval for Hycamtin capsules for the treatment ... Pay-Per-View - Chain Drug Review - HighBeam Research GlaxoSmithKline Gets New FDA Hycamtin OK and Bristol-Meyers … - Jun 16, 2006 City of Industry, CA - Pharmaceuticals Instruments industry alert provided by US Equity News. British drug maker GlaxoSmithKline PLC (NYSE:GSK) said ... Free with registration - M2 Presswire - AccessMyLibrary.com Hycamtin cleared. - Nov 19, 2007 GlaxoSmithKline PLC has received approval for Hycamtin capsules for the treatment of relapsed small-cell lung cancer. According to GSK, the product is the ... $9.94 - Chain Drug Review - Alacra Store International Approvals: Rotarix, Hycamtin, Pulmicort HFA - Mar 6, 2006 March 6, 2006 — The European Commission has approved a live attenuated rotavirus vaccine for the prevention of rotavirus gastroenteritis in infants, ... Medscape Hycamtin® oral, de GlaxoSmithKline, recibe la opinión positiva del... - Jan 31, 2008 Madrid, 31 de enero de 2008. El CHMP (Comité de Medicamentos de Uso Humano), órgano dependiente de la Agencia Europea del Medicamento (EMEA), ha otorgado la ... acceso.com Hycamtin.(Priority review)(Brief article) - Aug 1, 2007 Topotecan (Hycamtin, GlaxoSmithKline) for the treatment of relapsed small cell lung cancer (SCLC) $4.95 - Formulary - ECNext … for late-stage cervical cancer.(Hycamtin from GlaxoSmithKline PLC ... - Sep 1, 2006 The FDA has approved a combination of Hycamtin (topotecan hydrochloride) and cisplatin for use as the first drug treatment for women with late-stage cancer ... $4.95 - FDA Consumer - ECNext Hycamtin.(Priority review) - Sep 1, 2007 Oral topotecan (Hycamtin, GlaxoSmithKline) for the treatment of relapsed small cell lung cancer (SCLC) $4.95 - Formulary - ECNext FDA accepts sNDA on GSK's Hycamtin.(GlaxoSmithKline PLC)(New Drug … - Feb 27, 2006 UK drug major GlaxoSmithKline says that its supplemental New Drug Application submitted to the US Food and Drug Administration on December 15, 2005, ... $4.95 - Pharma Marketletter - ECNext Press Release: GlaxoSmithKline Gets New FDA Hycamtin OK and Bristol- … - Jun 16, 2006 GlaxoSmithKline Gets New FDA Hycamtin OK and Bristol-Meyers Declares Dividends. from M2 Presswire. Highbeam Research – FREE Trial. Pay-Per-View - M2 Presswire - HighBeam Research Empresas.- 'Hycamtin' (GSK), único tratamiento indicado para pacientes... - Sep 18, 2008 El tratamiento con topotecan cápsulas duras, comercializado por GlaxoSmithKline (GSK) como 'Hycamtin', es el único agente oral quimioterápico aprobado como ... ecodiario Hycamtin gets EU OK for cervical cancer. - Dec 22, 2006 Hycamtin gets EU OK for cervical cancer. UK-based drug major GlaxoSmithKline says that the European Medicines Agency (EMEA) has approved its anticancer ... $9.94 - Pharma Marketletter - Alacra Store US BioDefense Wholly Owned Portfolio Company Stem Cell Research … - Feb 20, 2006 The company said the FDA will give Hycamtin a priority review for the expanded use in patients with well-advanced cervical cancer that has spread to distant ... Free with registration - M2 Presswire - AccessMyLibrary.com GSK's Hycamtin gets FDA OK. - Oct 22, 2007 The US Food and Drug Administration has approved UK drug major GlaxoSmithKline's anticancer agent Hycamtin (topotecan) for the treatment of relapsed ... $4.95 - Pharma Marketletter - ECNext … Human Use post-authorisation summary of positive opinion for Hycamt... - Oct 19, 2006 Union languages after the variation to the marketing authorisation has been granted by the European Commission. The full indication for Hycamtin is given. Pay-Per-View - EMEA (European Medicines Agency) - Factiva, from Dow Jones Triple-Chemo Regimen No Improvement in Ovarian Cancer - Aug 1, 2006 Rather than improving outcome, the addition of Hycamtin to the Paraplatin ... Data were available for 648 women in the Hycamtin arm and 639 women in the ... MedPage Today Loislaw Federal District Court Opinions - REID v. SMITHKLINE … - Apr 11, 2005 In November 2002 GSK conducted a two and a half week training program on Hycamtin and Navelbine for transfers to the Oncology division. ... Pay-Per-View - Loislaw Federal District Court Opinions - Loislaw FDA Approves First Drug Treatment for Late-Stage Cervical Cancer - Jun 17, 2006 This week it approved a combination of Hycamtin (topotecan hydrochloride) ... The treatment approval includes a new use for Hycamtin, which was approved in ... SeniorJournal.com GlaxoSmithKline leases Upper Merion, Pa., manufacturing site to... - Jul 19, 2005 Pfizer also will take over production of Hycamtin for GlaxoSmithKline on a ... Hycamtin is for ovarian and certain lung cancers and had modest sales of $45 ... Free with registration - Philadelphia Inquirer - AccessMyLibrary.com HYCAMTIN®, DE GLAXOSMITHKLINE, RECIBE LA AUTORIZACIÓN … - Feb 1, 2006 Londres, 1 de febrero de 2006. GlaxoSmithKline (GSK) anunció hoy que la Comisión Europea (CE) ha autorizado la indicación de HYCAMTIN® (topotecan) para el ... acceso.com NUEVA INDICACIÓN DE HYCAMTIN® (TOPOTECAN HCL) PARA EL … - Dec 20, 2006 LONDRES, diciembre 2006 – GlaxoSmithKline anuncia que la Agencia Europea del Medicamento (European Medicines Agency, EMEA) ha concedido la Autorización de ... acceso.com Hycamtin chữa trị ung thÆ° cổ tá» cung - Jul 1, 2006 CÆ¡ quan Quản lý Thá»±c phẩm và Dược phẩm FDA (Mỹ) má»›i cấp phép lÆ°u hà nh má»™t loại thuốc có tên Hycamtin dùng để Ä‘iá»?u trị ung thÆ° cổ tá» cung kết hợp vá»›i Ä‘iá»?u ... VietNamNet Empresas.- La Comisión Europea autoriza ´Hycamtin´ (GSK) para el … - Jan 2, 2006 La Comisión Europea ha autorizado la indicación de topotecam desarrollado por GlaxoSmithKline (GSK) como ´Hycamtin´ para el tratamiento de los pacientes con ... Medicinatv.com FDA approves drug for late cervical cancer - Jun 28, 2006 The combination of the drug, Hycamtin, and cisplatin is the first drug ... The FDA originally approved Hycamtin in 1996 for treating ovarian cancer and in ... msnbc.com GSK cancer drug receives extended indication - Dec 4, 2006 GlaxoSmithKline (GSK) has announced that its cancer drug Hycamtin (topotecan HCl) has been approved to treat recurrent cervical cancer in the EU. ... Hays Pharma EBSCOhost Connection: Drug Approved for Late-Stage Cervical Cancer. - Sep 1, 2006 The approval is a new indication for Hycamtin, which was approved in 1996 ... The combination of Hycamtin and cisplatin is specifically indicated for women ... Subscription - FDA Consumer - EBSCO Publishing What Is in the Pipeline at GlaxoSmithKline? - Feb 26, 2007 Hycamtin, a topo-isomerase I inhibitor, is an indicated therapy for ovarian cancer first-line therapy in phase III trials with expected filing for approval ... Cancer Focus GSK Drug Approved in Europe for Lung Cancer - Feb 3, 2006 GlaxoSmithKline's anticancer drug, Hycamtin, has been approved by European regulators for ... Hycamtin, already approved as a treatment for ovarian cancer, ... RedOrbit כימותרפיה לסרטן הרי×?ות מעתה בקפסולות לבליעה - Jun 7, 2008 ...×”× ×§×¨×? הייקמטין (Hycamtin), ×©× ×™×ª×Ÿ מעתה בקפסולות לבליעה ומיוצר בחברת התרופות גלקסו סמית ... הידען Empresas.- GlaxoSmithKline anuncia que la EMEA ha concedido la … - Dec 21, 2006 La autorización de comercialización para 'Hycamtin' se produce después de ... La mediana de supervivencia para 'Hycamtin' más cisplatino fue de 9,4 meses, ... Pay-Per-View - Europa Press - Servicio de Noticias... - Factiva, from Dow Jones Press Release: LILLY (ELI) & COMPANY - Asco Study - Non-Small Cell … - May 16, 2008 Article: Hycamtin(TM) Achieves Promising Results in Patients With ... ... Article: SMITHKLINE BEECHAM: Hycamtin approved for use as second-line ... ... Pay-Per-View - PR Newswire UK Disclose - HighBeam Research Glaxo gets EU approval for a lung cancer drugBRIEFING: LONDON | … - Feb 2, 2006 Hycamtin, administered via injection, can be used to treat patients whose first line of treatment was not successful in eliminating the cancer, Glaxo said. ... Pay-Per-View - International Herald Tribune - HighBeam Research Press Release: BioNumerik Commences Global Phase III Ovarian Cancer … - Feb 7, 2008 ...label trial to prospectively evaluate the safety and efficacy of Karenitecin compared to the chemotherapy drug topotecan (also known as Hycamtin(R)). ... Pay-Per-View - PR Newswire - HighBeam Research Women: New drug hope for lung cancer; HEALTH NEWS.(Features) | … - Feb 8, 2006 ...find The Mirror (London, England) articles. HYCAMTIN has been granted authorisation by the European Commission for treatment of small cell lung cancer (S... Pay-Per-View - The Mirror - HighBeam Research Article: Cancer drug receives expanded approval to treat late-stage … - Jun 15, 2006 The combination of the drug, Hycamtin, and cisplatin is the first drug ... The FDA originally approved Hycamtin in 1996 for treating ovarian cancer and in ... Pay-Per-View - AP Worldstream - HighBeam Research Press Release: US BioDefense Wholly Owned Portfolio Company Stem … - Feb 20, 2006 Successfully Completes Evaluation and Validation of Human Neural Crest Stem Cell Line and Glaxo's Hycamtin to Get Fast FDA Review. from M2 Presswire. Pay-Per-View - M2 Presswire - HighBeam Research Article: Cancer Drug Usage Expanded - AP Online | HighBeam Research … - Jun 15, 2006 The combination of the drug, Hycamtin, and cisplatin is the first drug ... The FDA originally approved Hycamtin in 1996 for treating ovarian cancer and in ... Pay-Per-View - AP Online - HighBeam Research … to Host R&D Investor Day and GlaxoSmithKline Gets New FDA Hycamtin... - Jun 16, 2006 Abraxis BioScience to Host R&D Investor Day and GlaxoSmithKline Gets New FDA Hycamtin OK. from M2 Presswire. Highbeam Research – FREE Trial. Pay-Per-View - M2 Presswire - HighBeam Research YourLIFE: HEALTH NEWS - New drug hope for lung cancer.(Features) | … - Feb 8, 2006 ...find The Mirror (London, England) articles. HYCAMTIN has been granted authorisation by the European Commission for treatment of small cell lung cancer (S... Pay-Per-View - The Mirror - HighBeam Research Press Release: LILLY (ELI) & COMPANY - FDA Grants Lilly's ALIMTA(R) … - Sep 29, 2008 Article: Hycamtin(TM) Achieves Promising Results in Patients With ... ... Article: SMITHKLINE BEECHAM: Hycamtin approved for use as second-line ... ... Pay-Per-View - PR Newswire UK Disclose - HighBeam Research Glaxo lung-cancer treatment approved for use with cisplatin. |... - Jun 15, 2006 15--GlaxoSmithKline PLC's lung-cancer treatment Hycamtin, once manufactured in Upper Merion, received federal approval today for use along with the generic ... Pay-Per-View - Philadelphia Inquirer - HighBeam Research Business News in Brief - Feb 2, 2006 GlaxoSmithKline PLC's cancer drug Hycamtin, manufactured in Upper Merion, received approval from the European Union for use against small-cell lung cancer. ... $2.95 - Philadelphia Inquirer - NewsBank Business News in Brief - Jun 16, 2006 GlaxoSmithKline PLC's lung-cancer treatment Hycamtin, once manufactured in Upper Merion, ... Hycamtin had relatively modest sales last year of $99 million, ... $2.95 - Philadelphia Inquirer - NewsBank Press Release: ASCO Study Confirms Importance of Histology in … - May 16, 2008 Article: Hycamtin(TM) Achieves Promising Results in Patients With ... ... Article: SMITHKLINE BEECHAM: Hycamtin approved for use as second-line ... ... Pay-Per-View - PR Newswire - HighBeam Research Press Release: GlaxoSmithKline Reports Further Progress of Oncology … - Apr 22, 2008 New data will also be presented for HYCAMTIN(R) (topetecan HCl). GSK will also present data for several investigational medicines, including the oral ... Pay-Per-View - PR Newswire - HighBeam Research Article: Guidelines: treat lung cancer aggressively.(Clinical Rounds)... - Jun 15, 2005 Article: Hycamtin(TM) Achieves Promising Results in Patients With ... ... Article: SMITHKLINE BEECHAM: Hycamtin approved for use as second-line ... ... Pay-Per-View - Family Practice News - HighBeam Research Press Release: Perceptronix Receives Health Canada License for Early ... - Aug 21, 2006 Article: Hycamtin(TM) Achieves Promising Results in Patients With ... ... Oncology (ASCO), Hycamtin(TM) (topotecan hydrochloride for ... suffering from ... Pay-Per-View - PR Newswire Europe - HighBeam Research Press Release: Perceptronix Receives Health Canada License for Early ... - Aug 21, 2006 Article: Hycamtin(TM) Achieves Promising Results in Patients With ... ... Oncology (ASCO), Hycamtin(TM) (topotecan hydrochloride for ... suffering from ... Pay-Per-View - PR Newswire - HighBeam Research Press Release: FDA Grants Lilly's ALIMTA(R) (Pemetrexed for Injection)... - Sep 29, 2008 Article: Hycamtin(TM) Achieves Promising Results in Patients With ... ... Article: SmithKline Beecham's Hycamtin(R) Recommended for Approval by FDA ... ... Pay-Per-View - PR Newswire - HighBeam Research Article: Chemoradiation can boost lung cancer survival: locally... - May 1, 2005 Article: Hycamtin(TM) Achieves Promising Results in Patients With ... ... Article: SMITHKLINE BEECHAM: Hycamtin approved for use as second-line ... ... Pay-Per-View - Internal Medicine News - HighBeam Research Product news from the 06/20/06 News Brief - Jun 20, 2006 The FDA approved the expanded indication of GlaxoSmithKline's ovarian and lung cancer drug Hycamtin (topotecan HCI), as a treatment for advanced cervical ... Medical Marketing & Media - Medical Marketing and Media Article: Treatment of late stage non-small cell lung cancer: we have... - Nov 1, 2005 Article: Hycamtin(TM) Achieves Promising Results in Patients With ... ... Article: SMITHKLINE BEECHAM: Hycamtin approved for use as second-line ... ... Pay-Per-View - Southern Medical Journal - HighBeam Research Bird Flu Not Forgotten By GlaxoSmithKline - May 19, 2008 The approval is the latest in a string of small positives for the British company, which also got European approval for lung cancer drug Hycamtin earlier ... Forbes Average Increase in Price of Cancer Drugs Below CPI Trend - Oct 9, 2006 For example, the price of Hycamtin, an injectable chemotherapy for the treatment of ovarian cancer, increased 10% in 2006 while the cost of carboplatin ... Genetic Engineering News - Genetic Engineering News (press release) Meeting Highlights From The Committee For Medicinal Products For … - Oct 16, 2006 Hycamtin (topotecan), from SmithKline Beecham Plc, received a positive ... Hycamtin was first granted a marketing authorisation in the European Union on 12 ... Medical News Today - Medical News Today (press release) Article: New resources for cancer patients.(News)(Brief Article) -... - Aug 1, 2005 Beecham product web site; www.hycamtin ... tapes and books for people living with ovarian and ... launched an updated web site, www.hycamtin ... and ... Pay-Per-View - Internal Medicine News - HighBeam Research Press Release: Vion Pharmaceuticals Presents Initial Data From a... - Oct 26, 2006 Article: Hycamtin(TM) Achieves Promising Results in Patients With ... ... Article: SmithKline Beecham's Hycamtin(R) Recommended for Approval by FDA ... ... Pay-Per-View - PR Newswire - HighBeam Research Press Release: Threshold Pharmaceuticals Initiates Phase 2 Clinical... - Feb 5, 2007 Article: Hycamtin(TM) Achieves Promising Results in Patients With ... ... Article: SmithKline Beecham's Hycamtin(R) Recommended for Approval by FDA ... ... Pay-Per-View - PR Newswire - HighBeam Research Press Release: Pharmion Initiates Pivotal Phase 3 Study of Amrubicin... - Oct 17, 2007 Article: Hycamtin(TM) Achieves Promising Results in Patients With ... ... Article: SmithKline Beecham's Hycamtin(R) Recommended for Approval by FDA ... ... Pay-Per-View - PR Newswire - HighBeam Research Press Release: Avastin is Leading the Way for New Targeted Therapies ... - Dec 10, 2007 Article: Hycamtin(TM) Achieves Promising Results in Patients With ... ... Article: SmithKline Beecham's Hycamtin(R) Recommended for Approval by FDA ... ... Pay-Per-View - PR Newswire - HighBeam Research SMOKING CESSATION AIDS - COMPETITION - 2007/01/01 - TF Market … - Jan 1, 2007 GSK Receives FDA Approval for Hycamtin (R) ... 23, 1. GSK Receives EU Approval for Rotarix. ... Hycamtin, 27, 1. Navelbine, 27, 1. Cardiovascular, 27, 1 ... $3,450.00 - GLOBAL INDUSTRY ANALYSTS KEY PLAYERS - Alacra Store Press Release: View Details on the Top 20 Companies with Products in ... - Aug 24, 2007 Article: Hycamtin(TM) Achieves Promising Results in Patients With ... ... Article: SMITHKLINE BEECHAM: Hycamtin approved for use as second-line ... ... Pay-Per-View - M2 Presswire - HighBeam Research Press Release: OncoGenex Announces Encouraging Data from a Phase I … - May 3, 2006 Article: Hycamtin(TM) Achieves Promising Results in Patients With ... ... Article: SmithKline Beecham's Hycamtin(R) Recommended for Approval by FDA ... ... Pay-Per-View - PR Newswire - HighBeam Research Press Release: Sunesis Pharmaceuticals Initiates Phase II Clinical... - Mar 20, 2006 Article: Hycamtin(TM) Achieves Promising Results in Patients With ... ... Article: SmithKline Beecham's Hycamtin(R) Recommended for Approval by FDA ... ... Pay-Per-View - PR Newswire - HighBeam Research Press Release: Today There Are No Less Than 170 Emerging … - May 8, 2007 Article: Hycamtin(TM) Achieves Promising Results in Patients With ... ... Article: SMITHKLINE BEECHAM: Hycamtin approved for use as second-line ... ... Pay-Per-View - M2 Presswire - HighBeam Research Brand Names/Synonyms: Hycamtin is also known by the following brand names and/or synonymsHycamptamine; Hycamptin; Hycamtin; TOPOTECAN, HYCAMTIN; TPT; TTC; Topotecan; Topotecan Hcl; Topotecan Hydrochloride; Topotecan Lactone; Topotecane [Inn-French]; Topotecanum [Inn-Latin] Drug Category: Hycamtin is categorized under the following by the FDA: Antineoplastic Agents; Enzyme Inhibitors; ATC:L01XX17 Dosage Forms: POWDER FOR SOLUTION Absorption: Not Available Interactions: [an error occurred while processing this directive] Chemical IUPAC Name: (S)-10-[(dimethylamino) methyl]-4-ethyl-4,9-dihydroxy-1H-pyrano[3', 4' |
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