Hydergine

This page contains recent news articles, when available, and an overview of Hydergine but does not offer medical advice. You should contact your physician with regard to any health issues or concerns.

Overview:

Hydergine (when available)

Pharmacology and use:
Ergoloid Mesylate may increase cerebral metabolism and blood flow. The role of this medication in the therapy of dementia is controversial. A recent controlled study in patients with Alzheimer's disease found that there was no advantage to the use of ergoloid mesylates compared to placebo, suggesting that ergoloid mesylates may lower scores on some cognitive and behavioral rating scales. Further study is needed to determine the risk-benefit profile of ergoloid mesylates in the treatment of dementia. For use as an adjunct therapy for patients with dementia

Mechanism Of Action:
Ergoloid mesylates act centrally, decreasing vascular tone and slowing the heart rate, and acts peripherally to block alpha-receptors. One other possible mechanism is the effect of ergoloid mesylates on neuronal cell metabolism, resulting in improved oxygen uptake and cerebral metabolism, thereby normalizing depressed neurotransmitter levels.

News Articles on Ergoloid Mesylate

Smart pills’n such: cognitive enhancement is “easy�? - but risky?  -  Dec 22, 2008
For piracetam and Hydergine, start with a Web search. For donezepil, see MS Mumenthaler, et al., Psychoactive drugs and pilot performance: a comparison of Lifeboat Foundation,

性命攸关：�?�物�?分介�?  -  Oct 29, 2008
It is used in the treatment of... 本�?适用于治疗...... In therapeutic doses (hydergine 新浪网,

RCI revises drug and steroid classifications  -  Aug 21, 2008
...“There is no specific evidence which clearly establishes the mechanism by which Hydergine® (ergoloid mesylates) preparations produce mental effects, The U.S. Trotting Association Newsroom,

From the Editor’s desk  -  Jun 30, 2008
This may explain why the pharmacological benefits of most botanical therapies such as ginkgo, hydergine, passion flower, valerian, a myriad of Chinese British Journal of Psychiatry (subscription),

Pros & cons of ergot fungus, a floral parasite  -  Jun 16, 2008
...of medical drugs from ergot fungus, including methergine (which is still used to halt bleeding after birth) and hydergine (which improves circulation). American Chronicle,

HEALTHY LIFE: New Macular Degeneration Treatment  -  Apr 11, 2008
Dry AMD drops: Hydergine is currently being tested on patients with dry AMD. Researchers say it is an antioxidant -- similar to a vitamin -- that prevents KCRG,

Rambling into eternity: Part 3  -  Apr 3, 2008
Royal jelly, coenzyme Q10, DMAE, l-deprenyl, salmon oil, Piracetem, Hydergine, melatonin, vinpocetine, all kinds of goodies. There’s even LactAid, Georgia Straight,

Ask Dr. Weil: These drugs aren't so smart  -  11 Mar 2008
Another smart drug, Hydergine, is marketed as a nonspecific cerebral stimulant and is prescribed to help relieve symptoms of age- related mental decline. Arizona Daily Star,

Brand Names/Synonyms:
Hydergine is also known by the following brand names and/or synonyms:
Alkergot; CCK 179; Circanol; Co-Dergocrine Mesylate; Deapril-St; Dihydroergotoxin Mesilat; Dihydroergotoxin Mesylate; Dihydroergotoxin Methanesulfonate; Dihydroergotoxine Mesilate; Dihydroergotoxine Mesylate; Dihydroergotoxine Methanesulfonate; Dihydroergotoxine Methanesulphonate; ERGOLOID MESYLATES; Ergoloid Mesylate; Ergoloid Mesylates; Ergoloid Mesylates [Usan]; Gerimal; Hydergin; Hydergine; Hydergine Lc; Hydrogenated Ergot Alkaloids; Ischelium; Redergin; Trigot

Drug Category:
Hydergine is categorized under the following by the FDA: Adrenergic alpha-Antagonists; Nootropic Agents; Vasodilator Agents; Sympatholytics; ATC:C04AE01

Dosage Forms:
CAPSULE; LIQUID; POWDER; POWDER FOR SOLUTION; SOLUTION; SYRUP; TABLET

Absorption:
Rapidly but incompletely (~ 25%) absorbed from the gastrointestinal tract. Approximately 50% of the absorbed dose is eliminated by first-pass metabolism.

Interactions:
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Chemical IUPAC Name:
Not Available

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