Imipramine

This page contains recent news articles, when available, and an overview of Imipramine but does not offer medical advice. You should contact your physician with regard to any health issues or concerns.


Overview:

Imipramine
(when available)

Pharmacology and use:
Imipramine is a tricyclic antidepressant with general pharmacological properties similar to those of structurally related tricyclic antidepressant drugs such as amitriptyline and doxepin. A tertiary amine, imipramine inhibits the reuptake of serotonin more so than most secondary amine tricyclics, meaning that it blocks the reuptake of neurotransmitters serotonin and noradrenaline almost equally. It is also effective in migraine prophylaxis, but not in abortion of acute migraine attack. For the relief of symptoms of depression and as temporary adjunctive therapy in reducing enuresis in children aged 6 years and older.

Mechanism Of Action:
Imipramine works by inhibiting the re-uptake of the neurotransmitters norepinephrine and serotonin by nerve cells. It binds the Sodium-dependent serotonin transporter and Sodium-dependent noradrenaline transporter, preventing or reducing the reuptake of norepinephrine and serotonin by nerve cells. As norepinephrine and serotonin are used to stimulate the synapse, and depression has been linked to a lack of stimulation of the recipient neuron at a synapse, slowing the reuptake of these neurotransmitters allows them to remain in the synaptic gap longer than it normal, increasing the stimulation of the recipient neuron and relieving the symptoms of depression. However, it does not act primarily by stimulation of the central nervous system. The clinical effect is also hypothesized as being due to potentiation of adrenergic synapses by blocking uptake of norepinephrine at nerve endings.

News Articles on Imipramine

Limits to antidepressants' effectiveness: study  -  05 Jan 2010
Combining data from six studies that examined the effectiveness of two commonly prescribed antidepressants -- paroxetine and imipramine -- found the drugs ... Reuters

Les antidépresseurs ont très peu d'efficacité pour les dépressions légères et ...  -  05 Jan 2010
Les doses d'imipramine utilisées étaient aussi insuffisantes selon Hellerstein qui considère toutefois que cette étude met tout de même en lumière le peu ... PsychoMédia

항우울제 효과, 매우 심ê°?한 환ìž?ì—?서만 나타나  -  05 Jan 2010
...펜실베니아 대학ì?˜ 로버트 드루베스 박사는 ì?¼ë°˜ì ?으로 ë§Žì?´ 사용ë?˜ëŠ” GSKì?˜ 'íŒ?실(Paxil, paroxetine)'ê³¼ ì?´ë¯¸í”„ë?¼ë¯¼(imipramine)ì—? 대한 효과를 조사한 6ê±´ì?˜ 연구를 ... 메디게이트뉴스

Lena Palaniyappan , Lisa Insole and Nicol Ferrier  -  ‎Jan 3, 2010‎
Albers LJ, Reist C, Helmeste D, et al (1996) Paroxetine shifts imipramine metabolism. Psychiatry Research; 59: 189–96.[CrossRef][Medline] Alvan G, ... Adv Psychiatric Treat (subscription)

St. John's wort - The Cataract Connection  -  ‎Dec 10, 2009‎
...imipramine [Tofranil]; and sertraline [Zoloft], in the treatment of mild to moderate depression with far fewer side effects of standard antidepressants. ... InjuryBoard.com (blog)

Pharmacotherapy for borderline personality disorder: Cochrane systematic ...  -  ‎Dec 31, 2009‎
...lithium, oxcarbazepine), antidepressants (eg tranylcypromine, reboxetine, venlafaxine, duloxetine, sertraline, paroxetine, desipramine and imipramine), ... British Journal of Psychiatry

Brain serotonin-2 receptors in acute mania  -  ‎Dec 31, 2009‎
For instance, the studies of cerebrospinal fluid 5-hydroxyindoleacetic acid (5-HIAA) levels, platelet 5-HT uptake or tritiated imipramine binding sites in ... British Journal of Psychiatry

Pintar Membaca Obat  -  ‎Dec 9, 2009‎
Namun, dua jenis yang sering digunakan, yaitu obat tricyclic seperti amitriptiline dan imipramine serta selective serotonin re-uptake inhibitors (SSRIs) ... KOMPAS.com

FAQ: Pain Medications  -  ‎Nov 8, 2009‎
...antidepressants, which may relieve certain kinds of chronic pain. Common antidepressants include amitriptyline, trazodone, and imipramine. 24 Medica

What Is Enuresis? What Is Nocturnal Bedwetting?  -  ‎Nov 4, 2009‎
The antidepressant imipramine (Tofranil) may provide bed-wetting relief by changing a child's sleeping and waking pattern. The medication may also increase ... Medical News Today

Excerpts from Robert Whitaker's Anatomy of an Epidemic: Psychiatric Drugs and ...  -  ‎Oct 30, 2009‎
At the end of 16 weeks (in a study comparing cognitive behavior therapy, interpersonal therapy, the tricyclic antidepressant imipramine and placebo) there ... The People's Voice (blog)

Horse Sleep Disorders and Seizures Reviewed for Equine Vets  -  ‎Nov 3, 2009‎
In both adults and foals, the sleep attacks appear to be lifelong conditions, but can sometimes be treated with the antidepressant drug imipramine ... TheHorse.com

Which Antidepressants Treat Comorbid Anxiety and Depression?  -  ‎Oct 28, 2009‎
...[9,10] Tricyclic antidepressants (TCAs) (eg, amitriptyline, imipramine) are considered second-line treatments, given the concerns of safety and tolerability ... Medscape

Suffering from Chronic Pain  -  ‎Oct 27, 2009‎
...doctors are prescribing medications, like certain tricyclic antidepressants (such as amitriptyline and imipramine), to address that sensitivity, ... MSN Health & Fitness

Å afrán - přírodní pomoc pÅ™i depresích  -  ‎Nov 2, 2009‎
Comparison of Crocus sativus L. and imipramine in the treatment of mild to moderate depression: A pilot double-blind randomized trial. ... Pressweb (press release)

Study Says Depression May Weaken Bones  -  Oct 30, 2006
Imipramine is a tricyclic antidepressant, one of a group of older drugs that predate ... When the depressed mice drank water laced with imipramine, ... WebMD

Imipramine and Duloxetine for Urinary Incontinence Treatment  -  Sep 17, 2008
Duloxetine is an antidepressant called a "selective serotonin and norepinephrine reuptake inhibitor." It changes how the brain uses certain brain chemicals. ... WebMD

What's the evidence for tricyclic antidepressants?  -  Dec 4, 2008
The studies looked mainly at the tricyclic antidepressant imipramine. The reviews and studies found that imipramine helps to reduce the symptoms of panic ... guardian.co.uk

Learn about Imipramine from Consumer Reports Health.  -  Jan 8, 2007
A small number of children, teenagers, and young adults (up to 24 years of age) who took ... Full Alert. Imipramine tablets and capsules are used to treat ... consumerreports.org

How to take Imipramine from Consumer Reports Health.  -  Jan 8, 2007
A small number of children, teenagers, and young adults (up to 24 years of age) who took ... Full Alert. tell your doctor and pharmacist if you are allergic ... consumerreports.org

Man who gave teen fatal pill overdose sentenced  -  Dec 14, 2006
White, 39, a previously convicted sex offender, had earlier pleaded guilty to giving an excessive amount of the antidepressant imipramine to Samantha ... Deseret News

Man, 39, held: He already faces sex and abuse counts, and could be …  -  Aug 17, 2006
The toxicology report says the girl died from ingesting imipramine. Based on his interview with police and evidence at the scene, White was charged last ... $2.95 - Salt Lake Tribune, The - NewsBank

The Use of Imipramine ("Tofranil") and Other Psychotropic Drugs in …  -  Nov 1, 2005
Organic emotionalism appears as inseparable from mood and sentiment as normal emotion, and however transiently felt usually goes with a sense of sadness or ... British Journal of Psychiatry (subscript...

Antidepressants; Effects of imipramine and citalopram on cortical...  -  Feb 21, 2005
2005 FEB 21 - (NewsRx.com & NewsRx.net) -- Cortical gene expression changes induced by imipramine and/or citalopram have been identified in a rat model. ... Pay-Per-View - Mental Health Weekly Digest - Factiva, from Dow Jones

imipramine (drug) -- Britannica Online Encyclopedia  -  Jun 5, 2008
Britannica online encyclopedia article on imipramine (drug), synthetic drug used in the treatment of depression and enuresis (bed-wetting). Subscription - Encyclopedia Britannica

Teen's homicide leads to a 20-year sentence  -  Dec 15, 2006
Police said the girl ingested a lethal dose of imipramine, an anti-depressant. White - who claims he also ingested the pills - woke up the next morning, ... $2.95 - Salt Lake Tribune, The - NewsBank

… patients with panic disorder taking imipramine.(Panic Disorder)(cog...  -  May 1, 2007
Panic disorder patients treated with imipramine and cognitive behavioral ... Data from 172 participants were used--83 from the imipramine-only group, ... Free with registration - Brown University Psychopharmacology... - AccessMyLibrary.com

Antidepressants; Effects of imipramine and citalopram on cortical...  -  Feb 25, 2005
2005 FEB 25 - (NewsRx.com & NewsRx.net) -- Cortical gene expression changes induced by imipramine and/or citalopram have been identified in a rat model. ... Pay-Per-View - Drug Week - Factiva, from Dow Jones

Sex offender admits giving overdose to teen  -  Nov 5, 2006
A toxicology report showed Mikesell had seven times the legal dose of the drug, imipramine, in her system. White also admitted to 2nd District Judge Darwin ... $2.95 - Deseret News - NewsBank

can i take lithum and imipramine and klonopin together  -  May 4, 2008
...first of all it is very hard to take lithium anyway everyone knows that ..i've been bi-polar since i was eleven..my daughter is off too war ..is this combo ... HealthCentral.com

Antidepressants; Effects of imipramine and citalopram on cortical...  -  Feb 27, 2005
2005 FEB 27 - (NewsRx.com & NewsRx.net) -- Cortical gene expression changes induced by imipramine and/or citalopram have been identified in a rat model. ... Pay-Per-View - Medical Devices & Surgical Technology... - Factiva, from Dow Jones

Mich. Court of Appeals rules barred testimony prevented defendant...  -  May 5, 2008
Her autopsy revealed she had a "significant amount" of the antidepressant Imipramine in her system, leading the Bay County medical examiner to determine she ... $2.95 - Michigan Lawyers Weekly - NewsBank

Depression is a risk factor for osteoporosis  -  May 30, 2007
Moreover, they found that imipramine—a member of an older class of drugs called tricyclic antidepressants—reversed both depression and depression-induced ... News-Medical.net

Depression Model Leaves Mice with Molecular Scar  -  Mar 2, 2006
Notably, imipramine was unable to remove these silencer molecules, ... Imipramine reversed the suppressed BDNF gene expression by triggering a compensatory ... Kansas City infoZine

Popularity Doesn't Necessarily Make Prozac Best Antidepressant Choice  -  Dec 6, 2005
Patients found fluoxetine more tolerable than both Elavil or Endep (amitryptilline) and Tofranil (imipramine). Cipriani, a psychiatrist at the University of ... DG News

Pharmacy Your Health Treatment for this Painful Bladder Condition .  -  Jul 5, 2007
Amitriptyline and imipramine are tricyclic antidepressants which may be prescribed to help relax the bladder and block pain. ... Clinch Valley Times - Google News Archive

Illinois Administrative Code - 77 Ill. Adm. Code 790.5300 IMIPRAMINE ...  -  Aug 10, 2005
77 Ill. Adm. Code 790.5300 IMIPRAMINE HYDROCHLORIDE (Repealed) Repealed. (Source: Repealed at 17 Ill. Reg. 15916, effective September 20, 1993) ... Pay-Per-View - Illinois Administrative Code - Loislaw

TradeName : Antidep, Depranil, Depsol, Depsonil, Depsonil-PM, …  -  Jan 26, 2008
When it is to be taken : Imipramine is taken one or more times a day. ... Imipramine must be taken regularly to be effective. Do not skip doses, ... MedIndia

imipramine | Definition of imipramine | HighBeam.com: Online Dictionar...  -  Jul 12, 2006
Find out what imipramine means: The Oxford American College Dictionary has the definition of imipramine. Research related newspaper, magazine, ... Pay-Per-View - Oxford American College Dictionary - HighBeam Research

Antidepressants, Tricyclic (Systemic).(Drug overview)  -  Aug 1, 2006
Antibulimic Amitriptyline Clomipramine Desipramine Imipramine Anticataplectic ... One form of this medicine (imipramine) is also used to treat enuresis ... Free with registration - USP DI-Volume II, Advice for the... - AccessMyLibrary.com

Drug Therapy; Mg2+ efflux from erythrocytes studied, differential...  -  Mar 1, 2005
..."The effect of imipramine on Mg2+ efflux in NaCl medium (Na+/Mg2+ antiport), ... "The effects of imipramine on Na+/Mg2+ antiport and choline/Mg2+ antiport ... Pay-Per-View - Life Science Weekly - Factiva, from Dow Jones

Drug Therapy; Mg2+ efflux from erythrocytes studied, differential...  -  Mar 5, 2005
..."The effect of imipramine on Mg2+ efflux in NaCl medium (Na+/Mg2+ antiport), ... "The effects of imipramine on Na+/Mg2+ antiport and choline/Mg2+ antiport ... Pay-Per-View - Obesity, Fitness & Wellness Week - Factiva, from Dow Jones

Medical University of Berlin; Mg2+ efflux from erythrocytes studied, ...  -  Mar 2, 2005
..."The effect of imipramine on Mg2+ efflux in NaCl medium (Na+/Mg2+ antiport), ... "The effects of imipramine on Na+/Mg2+ antiport and choline/Mg2+ antiport ... Pay-Per-View - Biotech Week - Factiva, from Dow Jones

Vue v. Commissioner of Social Security, No. CIV S-06-1818-CMK (EDCal....  -  May 28, 2008
Dr. Kim noted she had some improvement with imipramine. She was to continue taking imipramine, and was prescribed Celexa, and Tylenol. ... $2.95 - U.S. District Court, Eastern District... - VersusLaw

Nadia M Tsankova, Olivier Berton, William Renthal, Arvind Kumar,...  -  Feb 26, 2006
Viral-mediated overexpression of HDAC5 blocks the ability of chronic imipramine to reverse behavioral deficits of chronic defeat stress. ... Nature.com

Nadia M Tsankova, Olivier Berton, William Renthal, Arvind Kumar,...  -  Feb 26, 2006
Chronic imipramine treatment in control mice induced a significant increase in Bdnf compared to that in control saline-treated mice (P < 0.05). ... Nature.com

Barbeau Pharma Announces That Its Studies Of The Cardiotoxicity Of …  -  Nov 22, 2005
Historically, imipramine has been used as an adjunctive therapy in combination with ... However, imipramine is not approved for use alone to treat nocturnal ... RedOrbit

La sertraline et l'imipramine améliorent la symptomatologie de la …  -  May 12, 2006
Thase ME, Fava M, Halbreich U et al. A placebo-controlled, randomized clinical trial comparing sertraline and imipramine for the treatment of dysthymia. ... EBM Journal (Abonnement)

Loislaw Federal District Court Opinions - VUE v. COMMISSIONER OF …  -  May 28, 2008
Dr. Kim noted she had some improvement with imipramine. She was to continue taking imipramine, and was prescribed Celexa, and Tylenol. Page 3 On October 14, ... Pay-Per-View - Loislaw Federal District Court Opinions - Loislaw

… la dépression : le rapport coût-efficacité de l'imipramine est...  -  May 12, 2006
Comparer les rapports coût-efficacité de l'imipramine et de la paroxétine ... Dans les hypothèses TS1, TS2 et TS3, le traitement par imipramine était d'un ... EBM Journal (Abonnement)

Is a combination of alarm and drug therapies effective in nocturnal …  -  Nov 14, 2005
Combination therapy with an alarm and either desmopressin or imipramine offered no advantage compared with alarm monotherapy. Nature.com

Michigan Court of Appeals Reports - PEOPLE v. YOST, 278 Mich. App. …  -  Mar 27, 2008
Monique had months earlier been prescribed the Imipramine to control ... On the basis of the level of Imipramine found in Monique's body and the ratio of ... Pay-Per-View - Michigan Court of Appeals Reports - Loislaw

Enurésie nocturne : l'imipramine est plus efficace que la miansérine  -  May 12, 2006
Smellie JM, McGrigor VS, Meadow SR, Rose SJ, Douglas ME. Nocturnal enuresis : a placebo controlled trial of two antidepressant drugs. ... EBM Journal (Abonnement)

Efficacy and tolerability of oral and intramuscular S-adenosyl- L- …  -  Feb 1, 2006
Results: In both studies, the results of SAMe and imipramine treatment did not differ significantly for any efficacy measure. However, significantly fewer ... Am J Clin Nutr (subscription)

Not a controlled substance  -  Nov 5, 2005
In 1976, Lippman and Pugsley reported that viloxazine, like imipramine, inhibited norepinephrine reuptake in the hearts of rats and mice; unlike imipramine, ... chemie.de

ASK AN EXPERT  -  Dec 7, 2007
The antidepressant imipramine (Tofranil) may provide bed-wetting relief by changing a child's sleeping ... Imipramine has few side effects for bed-wetters. ... CNN

Fourth International Consultation On Incontinence (ICI) - Drug...  -  Jul 24, 2008
Imipramine has non-selective antimuscarinic activity, alpha-adrenergic activity, and effects on renal water absorption. The committee noted serious issues ... Medical News Today - Medical News Today (press release)

Clinical Evidence Concise  -  Jun 1, 2007
One RCT found that imipramine was not as effective at improving remission as CBT was for bulimia, and the other found no significant difference in remission ... AAFP News Now

Antidepressant-like effect of Cecropia glazioui Sneth and its...  -  Jun 1, 2007
Imipramine (15mg/kg, ip) was employed as the antidepressant standard drug using ... Treatment with the tricyclic antidepressant imipramine (IMI 15 mg/kg, ... Free with registration - Phytomedicine: International Journal of... - AccessMyLibrary.com

Lavender (Lavandula angustifolia)  -  Jul 14, 2005
Imipramine alone was found to be more effective than lavendula alone, but the combination of the two was better than imipramine alone. ... Intelihealth.com

Pietrafeso v. Lawrence County, South Dakota, 452 F.3d 978 (8th Cir....  -  Jul 11, 2006
He has had anxiety background with Ativan and Imipramine. . . . He is at the point where he feels that he may need some systemic steroids, which he has been ... $2.95 - U.S. Court of Appeals, Eighth Circuit - VersusLaw

Nadia M Tsankova, Olivier Berton, William Renthal, Arvind Kumar,...  -  Feb 26, 2006
...(a) Hdac5 mRNA was significantly downregulated in chronically defeated mice receiving chronic imipramine (P < 0.01). This experiment was repeated twice, ... Nature.com

Nadia M Tsankova, Olivier Berton, William Renthal, Arvind Kumar,...  -  Feb 26, 2006
In contrast, chronic imipramine or fluoxetine treatment of defeated mice reversed the defeat stress–induced decrease in interaction to a level that was ... Nature.com

Bedwetting | Life and style | BMJ Group  -  Dec 4, 2008
In studies, up to one-third of children taking imipramine got side effects. These included anxiety, loss of appetite, constipation, depression, diarrhoea, ... guardian.co.uk

Depression Model Leaves Mice with Molecular Scar  -  Mar 1, 2006
Notably, imipramine was unable to remove these silencer molecules, ... Imipramine reversed the suppressed BDNF gene expression by triggering a compensatory ... emaxhealth.com

H. GIL RUSHTON, Children's National Medical Center, Washington, DC  -  May 1, 2006
One systematic review showed that the use of tricyclic drugs (imipramine, ... One small RCT showed that a combination of oxybutynin and imipramine increased ... AAFP News Now

Depression model leaves mice with molecular scar  -  Jan 3, 2006
Notably, imipramine was unable to remove these silencer molecules, ... Imipramine reversed the suppressed BDNF gene expression by triggering a compensatory ... innovations report - Innovations-Report

What's the evidence for applied relaxation?  -  Dec 4, 2008
A comparison of cognitive therapy, applied relaxation and imipramine in the treatment of panic disorder. British Journal of Psychiatry. 1994; 164: 759-769. ... guardian.co.uk

Neuropsychiatric manifestations of HIV infection and AIDS.(Review...  -  Jul 1, 2005
At 6 weeks of treatment, 74% of the imipramine group and 26% of the placebo group showed improvement of depressive symptoms without changes in CD3+/CD4+ ... Free with registration - Journal of Psychiatry and Neuroscience - AccessMyLibrary.com

Oral treatment of chronic peripheral diabetic neuropathy.(Drug...  -  Apr 1, 2006
Secondary amines (nortriptyline and desipramine) tend to produce fewer of these effects than do the tertiary amines (amitriptyline, imipramine). ... Pay-Per-View - Skin & Allergy News - HighBeam Research

Depression; Depression model leaves mice with molecular scar  -  Apr 4, 2006
Notably, imipramine was unable to remove these silencer molecules, ... Imipramine reversed the suppressed BDNF gene expression by triggering a compensatory ... Pay-Per-View - Life Science Weekly - Factiva, from Dow Jones

The Convergence of Conventional Therapeutic Drug Monitoring and …  -  Feb 28, 2007
In the case of amitriptyline, clomipramine, imipramine, and venlafaxine, the measurements of their active metabolites are also recommended. ... Nature.com

16th Meeting of the American Academy of Addiction Psychiatry: …  -  Dec 8, 2005
Imipramine treatment of alcoholism with comorbid depression. ... Imipramine treatment of alcoholics with primary depression: a placebo-controlled clinical ... Medscape

Treating depression in alcoholics curbs drinking.(Mental Health)  -  Feb 1, 2006
He gave imipramine to a group of alcoholic patients who appeared to have ... The more recent study suggested a response rate of 50% with imipramine ... Free with registration - Family Practice News - AccessMyLibrary.com

The Health Consequences of Antidepressants  -  Jul 17, 2006
Consider, for example, imipramine, an older antidepressant that has ... And there is the opposite problem: what if you've been on imipramine for years, ... HealthCentral.com

A Publication of BMJ Publishing Group  -  Jun 1, 2006
Two RCTs, primarily including persons with severe depression, showed no significant difference in symptoms between desipramine or imipramine and reboxetine ... AAFP News Now

Understanding and Using the Placebo Effect  -  Oct 1, 2006
In the more severely ill patients, imipramine, which was a popular antidepressant ... In the severely ill patients, imipramine worked better than any other ... Psychiatric Times

Sex Offender Suspected in Death of Utah Teen; Michael Jackson Facing ...  -  Jul 6, 2006
But the fact that he was on imipramine, which was an antidepressant, ... But it`s more likely that because imipramine is an antidepressant that`s also used ... CNN International

Glycogen synthase kinase-3 gene is associated with antidepressant …  -  Jan 15, 2008
Firstly, treatment with the antidepressants fluoxetine and imipramine was found to inhibit ... 3 In another study, pretreatment with imipramine attenuated ... Nature.com

Drugs With Special Side Effect Risks  -  Apr 18, 2006
Antidepressants: Effexor, Elavil, imipramine, Paxil, Prozac ... Antidepressants: Anafranil, Celexa, imipramine, Prozac, Zoloft. Cardiovascular: Inderal ... Pay-Per-View - Washington Post - ProQuest Archiver

Drugs With Special Side Effect Risks | Article from The Washington...  -  Apr 18, 2006
Antidepressants: Effexor, Elavil, imipramine, Paxil, Prozac ... Antidepressants: Anafranil, Celexa, imipramine, Prozac, Zoloft. Cardiovascular: Inderal ... Pay-Per-View - Washington Post - HighBeam Research

Tennessee Reports - BEAL v. WALGREEN CO., W2004-02925-COA-R3- …  -  Jan 12, 2006
Mrs. Beal's physician gave her a prescription for Imipramine. ... [fn1] The Food and Drug Administration approved Imipramine for the treatment of depression ... Pay-Per-View - Tennessee Reports - Loislaw

Refractory Enuresis Related To Alarm Therapy  -  Jan 26, 2007
The pharmacotherapy that was studied was DDAVP and imipramine. The group found that the effective rates of these 2 drugs for non-responders to alarm ... Medical News Today - Medical News Today (press release)

Pharmacologic treatment of psychotic depression.(Disease/Disorder …  -  Jun 1, 2006
An antidepressant such as imipramine (Tofranil) or sertraline (Zoloft), ... Based on these limited data, the preferred initial agents are imipramine and ... $4.95 - American Family Physician - ECNext

Correction.(Correction Notice)  -  Aug 1, 2005
Aventyl) Not recommended for elderly Imipramine (Tofranil) SNRIs Venlafaxine XR Immediate-release (Effexor) For moderate hepatic impairment Decrease ... $4.95 - Journal of Neuroscience Nursing - ECNext

Arrest coming in teen's death  -  Jul 7, 2006
Someone who doesn't need imipramine will experience ventricular defibrillation, or heart flutters, said Davis County Sheriff's Sgt. Tadd Lowe. ... Deseret News

ANTIHISTAMINE (Oral route, Parenteral route, Rectal route).(Drug …  -  May 1, 2007
Imipramine * Indinavir * Iproniazid * Isocarboxazid * Isoflurane * Itraconazole ... Imipramine * Isoflurane * Isradipine * Josamycin * Levorphanol ... Free with registration - USP DI-Volume II, Advice for the... - AccessMyLibrary.com

Treatment of panic disorder.  -  Feb 15, 2005
Boyer W. Serotonin uptake inhibitors are superior to imipramine and alprazolam ... Cognitive-behavioral therapy, imipramine, or their combination for panic ... Pay-Per-View - American Family Physician - Factiva, from Dow Jones

Le pourcentage de patients dépressifs poursuivant leur traitement est...  -  Nov 25, 2006
Existe-t-il un avantage à débuter le traitement des patients dépressifs par la fluoxétine plutôt que par la désipramine ou l'imipramine en termes ... EBM Journal (Abonnement)

Understanding Comorbid Depression and Anxiety  -  Dec 1, 2007
24 Findings from a study that compared the TCA imipramine with the SSRI fluoxetine suggest that the SSRI would be more effective in individuals with ... Psychiatric Times

Arrest coming in teen's death | Article from Deseret News (Salt Lake...  -  Jul 7, 2006
Someone who doesn't need imipramine will experience ventricular defibrillation, or heart flutters, said Davis County Sheriff's Sgt. Tadd Lowe. ... Pay-Per-View - Deseret News - HighBeam Research

CAPITOL WATCH: FOSTERING SUCCESS.(Editorial) | Article from …  -  Feb 10, 2005
The second most common pill for foster children was the anti-depressant imipramine ... SSRIs were prescribed to Washington foster children less often than ... Pay-Per-View - Seattle Post-Intelligencer - HighBeam Research

Clinical: Management for cases of bedwetting - The basics.  -  May 18, 2007
Imipramine is a tricyclic antidepressant, and the mechanism of its action in ... Although a child is four times more likely to become dry, imipramine has a ... Free with registration - GP - AccessMyLibrary.com

Search Results - The Austin Chronicle  -  Jun 23, 2006
DL-phenylalanine may also be an effective antidepressant drug on a par with imipramine, one of the first and, for a long time, the standard antidepressant ... Austin Chronicle

Antidepressants and antiepileptic drugs for chronic non-cancer pain.  -  Feb 1, 2005
Tertiary amines such as amitriptyline and imipramine (Tofranil) show more ... Venlafaxine versus imipramine in painful polyneuropathy: a randomized, ... $4.95 - American Family Physician - ECNext

Antidepressants for Bipolar Disorder  -  Jun 1, 2008
Patients treated with an antidepressant (paroxetine, imipramine, or fluoxetine) were more likely to achieve remission than those who were not taking an ... Psychiatric Times

FLUOROQUINOLONE (Oral route, Injection route, Intravenous route).( …  -  May 1, 2007
Imipramine * Lofepramine * Mesoridazine * Methotrimeprazine * Moricizine ... Imipramine * Insulin * Insulin Aspart, Recombinant * Insulin Glulisine ... Free with registration - USP DI-Volume II, Advice for the... - AccessMyLibrary.com

Antidepressants and antiepileptic drugs for chronic non-cancer pain.  -  Feb 1, 2005
Tertiary amines such as amitriptyline and imipramine (Tofranil) show more balanced ... imipramine (Tofranil) * 10 to 25 mg per week up to 75 to 150 ... Pay-Per-View - American Family Physician - Factiva, from Dow Jones

Abstract and Introduction  -  Mar 28, 2008
...[6] randomized participants to electroconvulsive therapy, imipramine or a Sudarshan Kriya yoga programme focused on rhythmic breathing. ... Medscape

SAMe I am: amino acid metabolite offers more than a mood boost.( …  -  Jan 1, 2005
In a head-to-head comparison with the antidepressant imipramine, SAMe performed equally well for major depression after 4 weeks, as noted in the December ... Free with registration - Better Nutrition - AccessMyLibrary.com

Antidepressants and Bipolar Disorder: Update From Recent Studies - …  -  May 1, 2006
...our re-analysis of the lithium-plus-paroxetine (or imipramine) study ... rate was 3 times higher with imipramine than with placebo (risk ratio, 3.14), ... Psychiatric Times

What is the best treatment for nocturnal enuresis in children?(CLINICA...  -  Oct 1, 2005
Medication choices include desmopressin and imipramine, although relapse rates are high. Short-term use of desmopressin may be used for sleepovers or ... Free with registration - Journal of Family Practice - AccessMyLibrary.com

A conspiracy of good intentions.(Prozac as a Way of Life)(Book Review)  -  Dec 1, 2005
The Swiss pharmaceutical company Geigy had actually refused to develop imipramine in the 1950s on the grounds that the market was too sluggish to provide a ... Free with registration - Quadrant - AccessMyLibrary.com

WHO expert committee on specifications for pharmaceutical preparations...  -  Aug 1, 2005
...trihexyphenidyl hydrochloride haloperidol trimethoprim hydrochlorothiazide valproic acid ibuprofen verapamil hydrochloride imipramine hydrochloride ... Free with registration - Technical Report Series - AccessMyLibrary.com

St. John's Wort.(COMPLEMENTARY AND ALTERNATIVE MEDICINE)( …  -  Dec 1, 2005
The authors of an earlier study (17) (n = 209) concluded that St. John's wort was equivalent to imipramine in patients with severe depression. ... Free with registration - American Family Physician - AccessMyLibrary.com

A preliminary study of tricyclic antidepressant (TCA) ovine FAB for...  -  Apr 1, 2006
1]; imipramine 15 x [10.sup.-9][M.sup.-1]; and desipramine 7.2 x [10.sup.-9][M.sup.-1]. The TCA Fab was provided as a solution of 1.5 grams Fab/30 mL in ... Free with registration - Clinical Toxicology - AccessMyLibrary.com

Sertraline (Systemic).(Drug overview)  -  May 1, 2006
Also, taking sertraline with amitriptyline, clomipramine, or imipramine may increase the chance of developing the serotonin syndrome Other medical problems ... Free with registration - USP DI-Volume II, Advice for the... - AccessMyLibrary.com

Last.fm: Web Service Beta  -  Sep 9, 2005
...doxepin (Sinequan), nortriptyline (Pamelor), imipramine (Tofranil), clomipramine (Anafranil), protriptyline (Vivactil), or desipramine (Norpramin). ... corante.com

Depression Can Hurt, Right Down to Your Bones  -  Nov 21, 2006
The researchers also found that using the anti-depressant imipramine -- sold in this country as Tofranil -- helped stave off not only the blues but also ... wtopnews.com

Psychiatric Times. How Quickly Do Antidepressants Begin to Work?  -  Oct 1, 2005
In one of the earliest descriptions of antidepressant therapy, Roland Kuhn (1957) suggested that the benefits of imipramine (Tofranil) could be observed ... Psychiatric Times

Sertraline (Systemic).  -  Feb 1, 2006
Also, taking sertraline with amitriptyline, clomipramine, or imipramine may increase the chance of developing the serotonin syndrome Other medical problems ... Free with registration - USP DI-Volume II, Advice for the... - AccessMyLibrary.com

Fluoxetine (Systemic).(Drug overview)  -  Aug 1, 2006
Also, taking amitriptyline, clomipramine, or imipramine with fluoxetine may increase the chance of developing the serotonin syndrome Thioridazine (eg, ... Free with registration - USP DI-Volume II, Advice for the... - AccessMyLibrary.com

Efficacy of Tricyclic Antidepressant is Associated with Beta2...  -  Dec 27, 2006
The IC patients were treated with imipramine hydrochloride, and the efficacy of treatment was assessed to be no change, fair, or good. ... UroToday International Journal

Clinical: Compact guidelines - Commentary - Your weekly review of key...  -  Aug 12, 2005
Although desmopressin and imipramine are of equal efficacy, treatment with imipramine has a higher risk of adverse effects and can be fatal in overdose. ... Free with registration - GP - AccessMyLibrary.com

Paroxetine (Systemic).  -  Oct 27, 2005
Also, taking paroxetine with amitriptyline, clomipramine, or imipramine may increase the chance that the serotonin syndrome will develop Warfarin (eg, ... Free with registration - USP DI-Volume II, Advice for the... - AccessMyLibrary.com

Brand Names/Synonyms:
Imipramine is also known by the following brand names and/or synonymsAntideprin; Apo-Imipramine; Berkomine; Censtim; Censtin; DPID; Declomipramine; Dimipressin; Dyna-Zina; Dynaprin; Estraldine; Eupramin; G-22355; IM; Imavate; Imidobenzyle; Imipramina; Imipramine; Imipramine Hcl; Imiprin; Imizin; Imizine; Imizinum; Impramine; Impril; Intalpram; Iramil; Irmin; Janimine; Melipramin; Melipramine; Nelipramin; Norfranil; Novopramine; Pramine; Prazepine; Presamine; Promiben; Psychoforin; Sk-Pramine; Surmontil; Surplix; Timolet; Tipramine; Tofranil; Tofranil, Base; Tofranil-Pm; Tofraniln A; Trimipramine Maleate

Drug Category:
Imipramine is categorized under the following by the FDA: Antidepressive Agents, Tricyclic; Norepinephrine-Reuptake Inhibitors; Adrenergic Uptake Inhibitors; ATC:N06AA02; ATC:N06AA03; ATC:N06AA06

Dosage Forms:
TABLET

Absorption:
Rapidly and well absorbed after oral administration

Interactions:
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Chemical IUPAC Name:
Not Available





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