Indinavir

This page contains recent news articles, when available, and an overview of Indinavir but does not offer medical advice. You should contact your physician with regard to any health issues or concerns.


Overview:

Indinavir
(when available)

Pharmacology and use:
Indinavir is a protease inhibitor with activity against Human Immunodeficiency Virus Type 1 (HIV-1). Protease inhibitors block the part of HIV called protease. HIV-1 protease is an enzyme required for the proteolytic cleavage of the viral polyprotein precursors into the individual functional proteins found in infectious HIV-1. Indinavir binds to the protease active site and inhibits the activity of the enzyme. This inhibition prevents cleavage of the viral polyproteins resulting in the formation of immature non-infectious viral particles. Protease inhibitors are almost always used in combination with at least two other anti-HIV drugs. For the treatment of HIV infection

Mechanism Of Action:
Indinavir inhibits the HIV viral proteinase enzyme which prevents cleavage of the gag-pol polyprotein, resulting in noninfectious, immature viral particles.

News Articles on Indinavir

The impact of societal changes on patterns of urolithiasis - Abstract  -  ‎Dec 31, 2009‎
...added to food or drug products, have also led to the appearance of previously unrecognized stone types, that is, melamine and indinavir calculi. ... UroToday

FDA Hands-Off On St. John's wort Cataract Connections (Part 3)  -  ‎Dec 14, 2009‎
On the FDA's Web site, the only warning is a 2000 Public Health Advisory warning of drug interactions with St. John's wort and indinavir, a drug used to ... InjuryBoard.com (blog)

SEXUALLY TRANSMITTED DISEASES:- THEIR NATURE AND CURE - THIRD PUBLICATION  -  ‎Dec 18, 2009‎
Didanosine, Efavirenz, Lamivudine, Stavudine, Indinavir, Nelfinavir, Abalavir. Eminence Consult Natural Medicine destroys HIV and cures AIDS. ... Modern Ghana

Ranbaxy gains WHO pre-qualification for Indinavir - 400mg ARV capsules  -  ‎Nov 13, 2009‎
Ranbaxy Laboratories Ltd (Ranbaxy) announced today that the World Health Organisation, Geneva (WHO), has included the Company's Indinavir (as sulfate) ... Equity Bulls

India's Ranbaxy gets WHO approval for AIDS drug  -  ‎Nov 12, 2009‎
BO), India's top drug maker by sales, said on Thursday it received the World Health Organization pre-qualification for its Indinavir anti-retroviral AIDS ... Reuters

Indian shares to open down; Larsen watched  -  ‎Nov 12, 2009‎
...the country's top drug maker by sales said it has received the World Health Organization pre-qualification for its Indinavir anti-retroviral AIDS drug. ... Reuters India

Market Closing: Manufacturing in the limelight!  -  ‎Nov 13, 2009‎
Ranbaxy, the domestic pharma major ended marginally lower on the bourses today despite one of its ARV (Anti Retro Viral) capsules Indinavir, ... India Business Blog (blog)

India stx up 1 pct, Larsen gains after share sale  -  ‎Nov 12, 2009‎
...the country's top drug maker by sales said it has received the World Health Organization pre-qualification for its Indinavir anti-retroviral AIDS drug. ... Reuters

Also in global health news: Funding shortfall in Philippines; WHO-approved ARV  -  ‎Nov 12, 2009‎
Indian drug maker Ranbaxy Laboratories announced on Thursday it had received WHO "pre-qualification for its Indinavir anti-retroviral AIDS drug. ... News-Medical.net

Govt Stake Sale Talks Lift India Indexes  -  ‎Nov 13, 2009‎
Ranbaxy Laboratories Limited decreased 0.4% to Rs 410.40 after the pharmaceutical industry said the company''s anti-retroviral AIDS drug Indinavir was ... 123Jump.com

FDA Approves Labeling Update for REYATAZ® (atazanavir sulfate) Capsules to ...  -  ‎Nov 5, 2009‎
...ergonovine, methylergonovine, cisapride, St. John's wort (Hypericum perforatum)-containing products, lovastatin, simvastatin, pimozide, or indinavir. ... WELT ONLINE

Postexposure Prophylaxis for HIV Infection  -  ‎Oct 28, 2009‎
Treatment with indinavir, zidovudine, and lamivudine in adults with human immunodeficiency virus infection and prior antiretroviral therapy. ... New England Journal of Medicine (subscription)

Ambuja Cements, ACC, Maytas, Ranbaxy: India Stock Preview  -  ‎Nov 12, 2009‎
Ranbaxy Laboratories Ltd. (RBXY IN): India's biggest drugmaker said yesterday the World Health Organization included its Indinavir capsules to treat ... Bloomberg

Dietary Supplements May Increase Longevity Of HIV Patients  -  ‎Nov 8, 2009‎
Specifically the use of St. John's Wort with Crixivan (indinavir sulfate) reduced the effectiveness of this medication. Other protease inhibitors are ... The AIDS Beacon (blog)

Market Watch  -  ‎Nov 5, 2009‎
The lower dose (2.5 mg) also is recommended for patients taking strong CYP3A4/5 inhibitors (eg, ketoconazole, atazanavir, clarithromycin, indinavir, ... The Hospitalist Online

Lower Norvir Boosting Dose Possible  -  ‎Oct 29, 2009‎
Hill and his colleagues also looked at studies with lopinavir (combined with ritonavir in Kaletra), Reyataz (atazanavir), Crixivan (indinavir) and Aptivus ... AIDSmeds.com HIV/AIDS Treatment News

New drug for type 2 diabetes  -  ‎Oct 29, 2009‎
Interactions: Potentiated by strong CYP3A4/5 inhibitors (eg, ketoconazole, atazanavir, clarithromycin, indinavir, itraconazole, nefazodone, nelfinavir, ... Clinical Advisor

Sensex gains 153 points, Nifty ends near 5K  -  ‎Nov 13, 2009‎
...the country's top drug maker by sales said it has received the World Health Organization pre-qualification for its Indinavir anti-retroviral AIDS drug. ... mydigitalfc.com

How antiretroviral therapy prolongs life  -  ‎Oct 21, 2009‎
...cause conformational changes at the active site of reverse transcriptase thereby inhibiting its activity. l Protease inhibitors such as indinavir, ... The Southern Times

Atazanavir et lithiases urinaires  -  ‎Nov 2, 2009‎
...pour l'autre, à l'indinavir (Crixivan®), inhibiteur de protéase. La spectrophotométrie a mis en évidence des cristaux d'atazanavir dans les calculs. ... vih.org

中国医è?¯äº§ä¸šç«žäº‰åŠ›æž„å»ºä¸Žå?¯æŒ?ç»­å?‘展  -  ‎Nov 2, 2009‎
...å¹´1月美国专利到期;奈韦拉平(Nevirapine),2011å¹´11月美国专利到期;å?Œæ ·å°†äºŽ2011å¹´11月美国专利到期的还有HIV感染治疗用è?¯èŒšåœ°é‚£éŸ¦ï¼ˆIndinavir)。 ... 中国生物技术信息网

Indinavir (Systemic).  -  Jul 28, 2005
Indinavir ( in-DIN-a-veer) is used, alone or in combination with other medicines, in the treatment of the infection caused by the human immunodeficiency ... Free with registration - USP DI-Volume II, Advice for the... - AccessMyLibrary.com

Indinavir (Systemic).(Drug overview)  -  May 1, 2006
Indinavir ( in-DIN-a-veer) is used, alone or in combination with other medicines, in the treatment of the infection caused by the human immunodeficiency ... Free with registration - USP DI-Volume II, Advice for the... - AccessMyLibrary.com

PSU to make HIV medicines indinavir sulfate 400, zidovudine 300, …  -  Aug 31, 2006
Pune, August 30: THE long-awaited revival of Hindustan Antibiotics Ltd (HA) may prove to be a damp squib on the operational front for the first PSU ... Expressindia.com

Argentinian generic indinavir compares well with Crixivan  -  Mar 28, 2005
Systemic exposure to indinavir is similar whether using Crixivan brand name indinavir or a generic indinavir formulation from Argentina, according to a ... Aidsmap

… sparing combination of ritonavir-boosted indinavir and efavirenz...  -  Aug 10, 2006
Patients who have failed an anti-HIV treatment regimen containing only nucleoside reverse transcriptase inhibitors (NRTIs) show modest improvements in fat ... Aidsmap

Dry skin affects up to half of adults with HIV  -  Oct 5, 2007
The association of indinavir use and dry skin was higher among men with a ... Of all the antiretrovirals, indinavir had the strongest association with dry ... Aidsmap

HIV/AIDS Therapy; 400 mg indinavir may be efficacious and less toxic ...  -  Feb 7, 2005
2005 FEB 7 - (NewsRx.com & NewsRx.net) -- 400 mg indinavir may be efficacious and less toxic than ritonavir and efavirenz. ... Pay-Per-View - AIDS Weekly - Factiva, from Dow Jones

Indinavir use not recommended for pregnant HIV-infected patients, FDA...  -  Jan 13, 2005
The protease inhibitor indinavir (Crixivan) is not recommended for use in pregnant women with HIV, according to a revision of the United States Food and ... Aidsmap

Long-Term Indinavir Treatment Keeps HIV Under Control at 156 Weeks: …  -  Oct 11, 2005
By Ed Susman. SAN FRANCISCO, CA -- October 11, 2005 -- Most patients who were treated with an antiretroviral regimen that included the protease inhibitor ... DG News

AIDS at 25: A Quarter Century of Medical Miracles  -  May 25, 2006
Merck's protease inhibitor (later called indinavir) initially did not look ... And there were dramatic 24-week results for indinavir in combination with AZT ... Medscape

HIV/AIDS-Related Infection; Indinavir directly impairs Cryptococcus …  -  Jan 4, 2005
..."In this report we investigated the effect(s) of the PI indinavir on protease ... "It was found that indinavir impaired cryptococcal protease activity in a ... Pay-Per-View - Virus Weekly - Factiva, from Dow Jones

Ritonavir Oral : Uses, Side Effects, Interactions, Pictures, Warnings...  -  Sep 30, 2008
When indinavir and didanosine are taken at the same time, ... If you take indinavir at the same time as your didanosine, the levels of indinavir in your ... WebMD

… di Scienze Igienistiche, Modena; Indinavir directly impairs...  -  Jan 5, 2005
..."In this report we investigated the effect(s) of the PI indinavir on protease ... "It was found that indinavir impaired cryptococcal protease activity in a ... Pay-Per-View - Biotech Week - Factiva, from Dow Jones

HIV/AIDS-Related Infection; Indinavir directly impairs Cryptococcus …  -  Jan 4, 2005
..."In this report we investigated the effect(s) of the PI indinavir on protease ... "It was found that indinavir impaired cryptococcal protease activity in a ... Pay-Per-View - TB & Outbreaks Week - Factiva, from Dow Jones

HIV/AIDS-Related Infection; Indinavir directly impairs Cryptococcus …  -  Jan 3, 2005
..."In this report we investigated the effect(s) of the PI indinavir on protease ... "It was found that indinavir impaired cryptococcal protease activity in a ... Pay-Per-View - Anti-Infectives Week - Factiva, from Dow Jones

HIV/AIDS-Related Infection; Indinavir directly impairs Cryptococcus …  -  Jan 7, 2005
..."In this report we investigated the effect(s) of the PI indinavir on protease ... "It was found that indinavir impaired cryptococcal protease activity in a ... Pay-Per-View - Drug Week - Factiva, from Dow Jones

HIV/AIDS-Related Infection; Indinavir directly impairs Cryptococcus …  -  Jan 5, 2005
..."In this report we investigated the effect(s) of the PI indinavir on protease ... "It was found that indinavir impaired cryptococcal protease activity in a ... Pay-Per-View - Immunotherapy Weekly - Factiva, from Dow Jones

HN84 Lagere dosis indinavir  -  Jul 10, 2007
Indinavir waarvan de bloedspiegel door ritonavir is opgevoerd, is een krachtige proteaseremmer, maar geeft relatief veel bijwerkingen (onder andere ... Hiv Vereniging Nederland

Johns Hopkins University; 400 mg indinavir may be efficacious and...  -  Feb 9, 2005
2005 FEB 9 - (NewsRx.com & NewsRx.net) -- 400 mg indinavir may be efficacious and less toxic than ritonavir and efavirenz. ... Pay-Per-View - Biotech Week - Factiva, from Dow Jones

HIV/AIDS Therapy; Indinavir/ritonavir 667/100 mg toxicity profile may...  -  Feb 10, 2005
2005 FEB 10 - (NewsRx.com & NewsRx.net) -- The toxicity profile of indinavir/ritonavir 667/100 mg may be similar to unboosted indivavir. ... Pay-Per-View - Blood Weekly - Factiva, from Dow Jones

Alopecia induced by lopinavir plus ritonavir therapy in an HIV...  -  Jul 1, 2007
There are several reports that link the protease inhibitor indinavir with ... Harry TC, Matthews M, Salvary I. Indinavir use: associated hair loss and mood ... $4.95 - Journal of Drugs in Dermatology - ECNext

La trithérapie associant indinavir, zidovudine et lamivudine diminue...  -  May 12, 2006
Gulick RM, Mellors JW, Havlir D, et al. Treatment with indinavir, zidovudine, and lamivudine in adults with human immunodeficiency virus infection and prior ... EBM Journal (Abonnement)

HIV/AIDS Therapy; Indinavir/ritonavir 667/100 mg toxicity profile may...  -  Feb 12, 2005
2005 FEB 12 - (NewsRx.com & NewsRx.net) -- The toxicity profile of indinavir/ritonavir 667/100 mg may be similar to unboosted indivavir. ... Pay-Per-View - Obesity, Fitness & Wellness Week - Factiva, from Dow Jones

Lopinavir-Ritonavir Oral: Dosage, Uses and Warnings  -  Oct 24, 2006
CLINICAL EFFECTS: Concurrent use of vardenafil with indinavir or ritonavir ... The US manufacturer of indinavir states that the dose of vardenafil should ... Medscape

HN70 Mozenavir (DMP450)  -  Jul 10, 2007
Een vierde groep kreeg indinavir in plaats van mozenavir. ... Diarree kwam bij het gebruik van indinavir vaker voor, misselijkheid ongeveer even vaak. ... Hiv Vereniging Nederland

Door Hiv Vereniging Nederland  -  Jul 10, 2007
Na een jaar was bijna de helft van de groep indinavir-gebruikers die de uitslagen niet te horen kreeg, van combinatie veranderd. ... Hiv Vereniging Nederland

Ministério da Saúde envia mais medicamentos ao Líbano  -  Aug 11, 2006
...estão sendo enviados lotes com aproximadamente 3,5 milhões de comprimidos de aminofilina 100 mg e em torno de 940 mil cápsulas de indinavir 400 mg. ... Terra Brasil

A Review of the Aetiology of Dyslipidaemia and Hyperlipidaemia in …  -  Oct 29, 2005
Clinically, even a single dose of a PI such as indinavir given to healthy volunteers is enough to induce reduced peripheral removal of glucose.10 In ... RedOrbit

Effets secondaires rénaux  -  Nov 13, 2007
Parmi les inhibiteurs de protéase, l'indinavir est l'antirétroviral le plus ... Ils sont dus à la cristallisation, c'est-à-dire au dépôt de l'indinavir sous ... Act Up-Paris

Antiretroviral therapy improves renal function among HIV-infected …  -  Jul 9, 2008
Certain antiretrovirals, such as tenofovir 12, 13 and indinavir, ... As participants did not receive tenofovir or indinavir as part of their initial HAART ... Nature.com

Indinavir (plasma, serum), klinisk kemi, Landstinget i Jönköping, …  -  Dec 18, 2007
Ett Na-Heparinrör (5 mL, grön propp (bild, nytt fönster)) alternativt rör utan gel (4 mL, röd propp (bild, nytt fönster)). Gelrör får ej användas. ... Landstinget i Jönköpings län

Probiotic supplementation improves symptoms in children with atopic …  -  Dec 22, 2005
Plasma samples were then collected for indinavir pharmacokinetic evaluation. ... Beginning on day 6 of vitamin C administration, 800 mg of indinavir every ... $4.95 - Original Internist - ECNext

Probiotic supplementation improves symptoms in children with atopic …  -  Dec 22, 2005
Plasma samples were then collected for indinavir pharmacokinetic evaluation. ... Beginning on day 6 of vitamin C administration, 800 mg of indinavir every ... Pay-Per-View - Original Internist - HighBeam Research

An AZ guide for essential terms relating to HIV/Aids  -  Oct 22, 2008
Indinavir (Crixivan): a protease inhibitor from Merck. Indinavir must be taken every eight hours on an empty or mostly empty stomach; fat interferes with ... The Times

Lopinavir/ritonavir not linked to hepatotoxicity regardless of HCV...  -  Jan 25, 2005
Regimens used included lopinavir boosted with 200 mg daily ritonavir (89 patients), unboosted indinavir (Crixivan) (100 patients), indinavir boosted with ... Aidsmap

Basic research paving way to clinical care -  -  Feb 12, 2007
It turns out that HIV-infected people taking drugs such as indinavir have a ... That means indinavir and its protease inhibitor cousins are blocking GLUT4 ... $1.95 - Worcester Telegram Gazette - NewsBank

Acute and chronic paronychia.(Disease/Disorder overview)  -  Feb 1, 2008
Indinavir is the most common cause of chronic or recurrent paronychia of the toes ... The mechanism of indinavir-induced retinoid-like effects is unclear. ... Free with registration - American Family Physician - AccessMyLibrary.com

Cai preço de remédio para aids  -  Feb 5, 2005
O menor preço para o Indinavir, por exemplo, é de US$ 285,00 por quilo do produto. Já o valor mais baixo encontrado no caso do lopinavir é de US$ 2,9 mil ... Paraná-Online - Paraná-Online (Assinatura)

Press Release: /CORRECTION - Schering-Plough Corporation/. - PR …  -  Jan 11, 2008
Article: Twice-Daily Indinavir/Ritonavir Regimens Effective. ... Both 400/400 mg and 800/100 mg twice-daily doses of indinavir and ritonavir ... based ... Pay-Per-View - PR Newswire - HighBeam Research

Costa diz que vai cobrar maior eficiência dos laboratórios públicos …  -  Mar 30, 2005
...desde novembro do ano passado e se agravou em fevereiro, quando os estoques de AZT, Atazanavir, Indinavir e Lamivudina foram praticamente zerados. ... Paraná-Online - Paraná-Online (Assinatura)

HIV/AIDS HAART; Protease inhibitors block adipocyte differentiation …  -  Jan 2, 2006
..."Although indinavir stimulated the accumulation of unprocessed lamin A," BA Kudlow and colleagues at the University of Washington wrote, ... Pay-Per-View - Anti-Infectives Week - Factiva, from Dow Jones

A 39-Year-Old Man With HIV-Associated Lipodystrophy  -  Aug 3, 2008
Other drugs previously received include lamivudine, indinavir, and ritonavir. ... It was a gradual change, and by the second year of being on [indinavir], ... Journal of American Medical Association - Journal of American Medical Association...

HIV/AIDS; Research from the United Kingdom, Brazil and Italy in HIV/ …  -  May 17, 2006
..."In this work, a simple and rapid electrokinetic chromatography method for the simultaneous separation of different protease inhibitors (indinavir, ... Pay-Per-View - Life Science Weekly - Factiva, from Dow Jones

Pharmacokinetics and Safety of Saquinavir/Ritonavir and Omeprazole in...  -  Feb 5, 2007
11 A reduction in AUC was also seen when omeprazole was given with the protease inhibitor indinavir 800 mg, three times daily. However, boosted indinavir ... Nature.com

Factiva Search  -  Mar 14, 2006
HIV/AIDS Drug Monitoring; Low urine pH associated with reduced indinavir crystalluria in indinavir-treated patients. 14 March, 2006 Life Science Weekly ... Pay-Per-View - Life Science Weekly - Factiva, from Dow Jones

Pancreatitis risk studied in 20 US HIV drug trials  -  Jun 2, 2005
HAART regimes including the protease inhibitor indinavir with 3TC/AZT, 3TC/d4T, ddI/3TC, ddI/AZT produced similar rates of clinical pancreatitis (0.42 per ... Aidsmap

Ritonavir Oral : Uses, Side Effects, Interactions, Pictures, Warnings...  -  Sep 30, 2008
Crixivan (indinavir sulfate) US prescribing information. ... Piscitelli SC, Burstein AH, Chaitt D, Alfaro RM, Falloon J. Indinavir concentrations and St ... WebMD

Press Release: Merck, Pfizer Releases Data on Drugs to Treat Diabetes....  -  Jun 25, 2007
Article: Twice-Daily Indinavir/Ritonavir Regimens Effective. ... Both 400/400 mg and 800/100 mg twice-daily doses of indinavir and ritonavir ... based ... Pay-Per-View - M2 Presswire - HighBeam Research

HIV/AIDS Therapy; Variable molecular structures contribute to...  -  Mar 29, 2005
..."The protease affinity for indinavir was estimated by calculating the averaged molecular mechanics interaction energy. A correlation coefficient of 0.96 was ... Pay-Per-View - Virus Weekly - Factiva, from Dow Jones

HIV/AIDS Therapy; Variable molecular structures contribute to...  -  Mar 28, 2005
..."The protease affinity for indinavir was estimated by calculating the averaged molecular mechanics interaction energy. A correlation coefficient of 0.96 was ... Pay-Per-View - Hematology Week - Factiva, from Dow Jones

HIV/AIDS Therapy; Variable molecular structures contribute to...  -  Apr 3, 2005
..."The protease affinity for indinavir was estimated by calculating the averaged molecular mechanics interaction energy. A correlation coefficient of 0.96 was ... Pay-Per-View - Medical Devices & Surgical Technology... - Factiva, from Dow Jones

Drug Interactions; Efavirenz lowers amprenavir AUCs but NEV/IDV/RTV …  -  Sep 19, 2005
2005 SEP 19 - (NewsRx.com) -- Efavirenz lowers amprenavir AUCs but nevirapine, indinavir or ritonavir compensates for efavirenz induction. ... Pay-Per-View - AIDS Weekly - Factiva, from Dow Jones

Antiretroviral Drug Resistance and Routine Therapy, Cameroon  -  Jun 13, 2006
NFV, nelfinavir; ATV, atazanavir; RTV, ritonavir; IDV, indinavir; PIs, protease inhibitors; NVP, nevirapine; EFV, efavirenz; non-NRTIs, non-nucleoside ... Medscape

Upper abdominal pain, nausea, and vomiting  -  Oct 7, 2007
Delavirdine, indinavir, nelfinavir and zalcitabine should be taken two hours prior to the ingestion of an antacid. [Burger-DM et al. ... Hiv Vereniging Nederland

Abstract and Introduction  -  Nov 3, 2005
Results of preliminary experiences using lopinavir/ritonavir [16-18] or indinavir/ritonavir [19] also support the use of boosted protease inhibitors as ... Medscape

Genetic test can help predict who will develop hyperbilirubinaemia  -  Sep 14, 2005
They calculated that universal provision of antiretroviral treatment including either atazanavir or indinavir would involve a 22% incidence of ... Aidsmap

Article: New twists in topical psoriasis therapies.(Dermatologic...  -  Aug 1, 2005
Article: Twice-Daily Indinavir/Ritonavir Regimens Effective. ... Both 400/400 mg and 800/100 mg twice-daily doses of indinavir and ritonavir, ... Pay-Per-View - Skin & Allergy News - HighBeam Research

PRESIDENT'S ADDRESS TO THE MEMBERS OF BOTH HOUSES OF …  -  Dec 1, 2006
Another medicine found is INDINAVIR with equally good results. A foreign University has tried a combination of AZT-INDINAVIR and 3TC, for some patients, ... pib.nic.in

HIV/AIDS Therapy; New findings in HIV/AIDS therapy described  -  Mar 1, 2005
Study 1: The toxicity profile of indinavir/ritonavir 667/100 mg may be similar to unboosted indivavir. "Human immunodeficiency virus (HIV) patients on ... Pay-Per-View - Life Science Weekly - Factiva, from Dow Jones

UGT1A1 promoter polymorphism increases risk of nilotinib-induced …  -  Jul 5, 2007
In contrast, indinavir is thought to be metabolized by UGT1A1, 10 and the adverse events associated ... Mechanism of indinavir-induced hyperbilirubinemia. ... Nature.com

HIV/AIDS Therapy; New findings in HIV/AIDS therapy described  -  Mar 2, 2005
Study 1: The toxicity profile of indinavir/ritonavir 667/100 mg may be similar to unboosted indivavir. "Human immunodeficiency virus (HIV) patients on ... Pay-Per-View - Immunotherapy Weekly - Factiva, from Dow Jones

USPHS releases updated guidelines for management of occupational …  -  Dec 1, 2005
Indinavir (Crixivan) with Potential for serious or life- or without ritonavir threatening drug interactions; serious toxicity possible; consumption of eight ... $4.95 - American Family Physician - ECNext

Door Hiv Vereniging Nederland  -  Jul 10, 2007
Een kleine groep van 12 hiv-positieven die succesvol gemiddeld 32 maanden combinatietherapie met door ritonavir opgevoerde indinavir had gebruikt, ... Hiv Vereniging Nederland

Door Kees Rümke  -  Jul 1, 2008
Berucht zijn ook de voedselregels van het in onbruik geraakte indinavir. ... Nuchter bij de inname van indinavir is: tenminste een uur voor of twee uur na ... Hiv Vereniging Nederland

Article: Efavirenz-based treatment better at reducing viral load.(Infe...  -  Sep 15, 2006
27%; P=0 ... with indinavir. The study established efavirenz plus two NRTIs as an effective option for ... Formulary. Article: Sustiva: NNRTI to be used in ... Pay-Per-View - Internal Medicine News - HighBeam Research

Article: Tx for noncompliant H. pylori patients.(CLINICAL CAPSULES)( …  -  Dec 1, 2005
Article: Twice-Daily Indinavir/Ritonavir Regimens Effective. ... Both 400/400 mg and 800/100 mg twice-daily doses of indinavir and ritonavir ... reported in ... Pay-Per-View - Pediatric News - HighBeam Research

Article: Valsartan indicated for cutting post-MI death risk.(Rx) -...  -  Sep 15, 2005
Article: Twice-Daily Indinavir/Ritonavir Regimens Effective. ... Both 400/400 mg and 800/100 mg twice-daily doses of indinavir and ritonavir ... based ... Pay-Per-View - Internal Medicine News - HighBeam Research

Lab studies show that protein in St John's wort can inhibit HIV, but...  -  Oct 31, 2005
This interaction can lead to low blood levels of indinavir, increasing the chance that HIV resistant to indinavir and other protease inhibitors will emerge. ... Aidsmap

Progress in Treating HIV Infection: State-of-the Art Issues and...  -  Aug 31, 2005
In CNAA 3005, [24] a double-blind comparison of abacavir vs indinavir, both with zidovudine/lamivudine, the subset of patients with a baseline HIV RNA ... Medscape

HAART agents can cause adverse skin reactions.(Infectious Diseases)  -  Mar 1, 2006
Indinavir, ritonavir, stavudine, and zidovudine can cause lipodystrophy. ... Indinavir can cause retinoidlike effects that include recurrent paronychia, ... Pay-Per-View - Internal Medicine News - Factiva, from Dow Jones

Acute kidney failure more common in people newly diagnosed with HIV  -  Jun 25, 2008
After indinavir was discontinued as a commonly-used HIV drug, ARV-related ... These included six cases of indinavir-related kidney stones (all in the early ... Aidsmap

Note d'information aux patients sur les données de COPHAR I  -  May 3, 2005
Pour l'indinavir, les concentrations résiduelles mesurées ont été comprises entre 17 et 1 252 ng/ml ; les concentrations mesurées au pic ont été comprises ... survivreausida.net

Localized Mycobacterium avium complex infection of vertebral and …  -  Feb 1, 2006
His symptoms were attributed to indinavir-induced nephrolithiasis, and this was replaced by tenofovir. Despite the change and the use of ibuprofen, ... $4.95 - Southern Medical Journal - ECNext

HIV/AIDS Therapy; Protease inhibitors impair glucose-stimulated...  -  Mar 21, 2005
No such effects on signaling were observed with amprenavir or indinavir," M. Schutt and colleagues reported. The authors conclude that certain "HIV-1 ... Pay-Per-View - Obesity & Diabetes Week - Factiva, from Dow Jones

HIV/AIDS Drug Action; Pharmacodynamics of CYP3A inactivation by HIV …  -  Apr 12, 2005
..."All the PIs, except indinavir," reported CS Ernest and colleagues at Wishard ... Saquinavir and indinavir did not show time- and concentration-dependent ... Pay-Per-View - Life Science Weekly - Factiva, from Dow Jones

Door Hiv Vereniging Nederland  -  Jul 10, 2007
Toen gebeurde het dan toch nog (Indinavir en saquinavir volgden kort na ritonavir). Op 31 mei kwam Borst dan toch met een brief aan de toenmalige ... Hiv Vereniging Nederland

Ruhr University of Bochum; Protease inhibitors impair glucose...  -  Mar 23, 2005
No such effects on signaling were observed with amprenavir or indinavir," M. Schutt and colleagues reported. The authors conclude that certain "HIV-1 ... Pay-Per-View - Biotech Week - Factiva, from Dow Jones

Drug Monitoring; Automated LC/LC-MS rapidly analyses samples for …  -  Jan 2, 2005
..."The 6 PIs, amprenavir, indinavir, ritonavir, lopinavir, nelfinavir, ... A nonlinear fit (y-1=a+b/x, all r(2)>0.999) for amprenavir, indinavir, ritonavir, ... Pay-Per-View - Medical Devices & Surgical Technology... - Factiva, from Dow Jones

Drug Monitoring; Automated LC/LC-MS rapidly analyses samples for …  -  Jan 1, 2005
..."The 6 PIs, amprenavir, indinavir, ritonavir, lopinavir, nelfinavir, ... A nonlinear fit (y-1=a+b/x, all r(2)>0.999) for amprenavir, indinavir, ritonavir, ... Pay-Per-View - Obesity, Fitness & Wellness Week - Factiva, from Dow Jones

HIV/AIDS Drug Action; Pharmacodynamics of CYP3A inactivation by HIV …  -  Apr 16, 2005
..."All the PIs, except indinavir," reported CS Ernest and colleagues at Wishard ... Saquinavir and indinavir did not show time- and concentration-dependent ... Pay-Per-View - Obesity, Fitness & Wellness Week - Factiva, from Dow Jones

HIV/AIDS Therapy; Protease inhibitors impair glucose-stimulated...  -  Mar 27, 2005
No such effects on signaling were observed with amprenavir or indinavir," M. Schutt and colleagues reported. The authors conclude that certain "HIV-1 ... Pay-Per-View - Medical Devices & Surgical Technology... - Factiva, from Dow Jones

Localized Mycobacterium avium complex infection of vertebral and …  -  Feb 1, 2006
His symptoms were attributed to indinavir-induced nephrolithiasis, and this was replaced by tenofovir. Despite the change and the use of ibuprofen, ... Pay-Per-View - Southern Medical Journal - HighBeam Research

Wishard Memorial Hospital, Indianapolis; Pharmacodynamics of CYP3A …  -  Apr 13, 2005
..."All the PIs, except indinavir," reported CS Ernest and colleagues at Wishard ... Saquinavir and indinavir did not show time- and concentration-dependent ... Pay-Per-View - Biotech Week - Factiva, from Dow Jones

Ritonavir Oral : Uses, Side Effects, Interactions, Pictures, Warnings...  -  Oct 24, 2006
If your are taking indinavir, do not take more than 2.5 mg of vardenafil every 24 hours. ... Crixivan (indinavir sulfate) US prescribing information. ... WebMD

Myelomeningocele in an Infant with Intrauterine Exposure to Efavirenz  -  Jun 9, 2005
Efavirenz plus zidovudine and lamivudine, efavirenz plus indinavir, and indinavir plus zidovudine and lamivudine in the treatment of HIV-1 infection in ... Nature.com

HN74 Nevirapine als cholesterolverlager?  -  Jul 10, 2007
Naast deze middelen krijgen ze indinavir of nevirapine of 3TC. In een substudie is gekeken naar het cholesterol bij de trialdeelnemers. ... Hiv Vereniging Nederland

Brochure Bijwerkingen - St Middelen  -  Jun 10, 2005
Bij gebruik van de proteaseremmer indinavir kunnen nierstenen ontstaan. Deze bestaan uit kristallen indinavir, al dan niet met calcium. ... Hiv Vereniging Nederland

Age-dependent Pharmacokinetics of Lamivudine in HIV-infected Children  -  Oct 15, 2006
Pharmacokinetics of the protease inhibitor indinavir in human immunodeficiency ... Pharmacokinetics of indinavir combined with low-dose ritonavir in human ... Nature.com

A Low Dose of Ritonavir-Boosted Atazanavir Provides Adequate …  -  Aug 15, 2008
16,17,18 As a result, drugs such as saquinavir and indinavir are ... Pharmacokinetics of reduced-dose indinavir/ritonavir 400/100 mg twice daily in ... Nature.com

HN73 Rumoer over therapietrouw  -  Jul 10, 2007
Wanneer je indinavir zonder ritonavir gebruikt zal je vrij stipt om de ... Wie indinavir met ritonavir neemt zal een grotere speelruimte hebben in tijd. ... Hiv Vereniging Nederland

Brochure Bijwerkingen - St Middelen  -  Jun 10, 2005
...(fos)amprenavir, delavirdine, indinavir, nelfinavir en zalcitabine dienen een uur voor of na een zuurbindend middel te worden ingenomen.[DM Burger et al.] ... Hiv Vereniging Nederland

Proteaseremmer of niet-nucleoside?  -  Jul 10, 2007
Een trial suggereert dat een combinatie met efavirenz beter is dan met indinavir en de Atlanticstudie suggereert dat een combinatie met indinavir even goed ... Hiv Vereniging Nederland

HN77 Kaletra en vrouwen  -  Jul 10, 2007
Eerder is een dergelijk sekseverschil ook aangetoond voor indinavir. Ook bij indinavir was de indinavir-spiegel bij vrouwen hoger dan bij mannen. ... Hiv Vereniging Nederland

Wisselwerking tussen alcohol en drugs en hiv-remmers (2)  -  Jul 17, 2005
Als je indinavir gebruikt, moet je extra water, thee of sap drinken om te ... Als je indinavir gebruikt en alcohol wilt drinken moet je nog meer extra water ... Hiv Vereniging Nederland

HN70 Vijf jaar combinatietherapie  -  Jul 10, 2007
Twee kleine trials met indinavir + AZT + 3TC respectievelijk indinavir + AZT + ddI ... In de VS werden saquinavir, ritonavir en indinavir in een enorm tempo ... Hiv Vereniging Nederland

HN84 Bloedspiegels, de juiste afspiegeling?  -  Jul 10, 2007
Indinavir bijvoorbeeld wordt slecht opgenomen wanneer het met voedsel gemengd ... Voor indinavir en efavirenz is ook een bovengrens bekend waarboven er meer ... Hiv Vereniging Nederland

Las mujeres, el VIH y la depresión  -  Oct 25, 2007
Esta hierba también tiene una interacción significativa con el indinavir (Crixivan). Los niveles sanguíneos del indinavir se reducen notablemente cuando se ... universia.net.co

Voor vragen over leven met hiv en de Hiv Vereniging Nederland  -  Jul 10, 2007
Bij een hoge bloedspiegel van indinavir wordt de kans op nierstenen groter. Als je er pas na vier uur voor inname van de volgende dosis achter komt dat je ... Hiv Vereniging Nederland

Door Hiv Vereniging Nederland  -  Jul 10, 2007
In de MaxCMin1 trial worden combinaties met onder andere indinavir + ritonavir ... Na 24 weken had 87% van hen die met de indinavir-combinatie begonnen een ... Hiv Vereniging Nederland

EU commission approves Aptivus® for the treatment of HIV  -  Oct 26, 2005
The comparator PIs were lopinavir, indinavir, saquinavir and amprenavir. In addition, patients in both arms received an optimized background regimen of ... biotech-intelligence.com

Brand Names/Synonyms:
Indinavir is also known by the following brand names and/or synonymsCompound J; Crixivan; Indinavir; Indinavir Sulfate; Indinavir [Usan]

Drug Category:
Indinavir is categorized under the following by the FDA: Anti-HIV Agents; ATC:J05AE02

Dosage Forms:
Oral capsules

Absorption:
Rapidly absorbed

Interactions:
[an error occurred while processing this directive]



Chemical IUPAC Name:
1-[2-hydroxy-4-[(2-hydroxy-2,3-dihydro-1H-inden-1-yl)carbamoyl]-5-phenyl-pentyl]-4-(pyridin-3-ylmethyl)-N-tert-butyl-piperazine-2-carboxamide





Health Home | Conditions | Cancer | Medications | Surgery | Vaccines


The Cancer News Network


Disclaimer:

Contact a physician with regard to health concerns. Email requests for further health information will be discarded.

The materials contained on this Web site are for informational purposes only and do not constitute health or medical advice. Use of information on this site does not create or constitute any kind of agreement or contract between you and the owners or users of this site, the owners of the servers upon which it is housed, or anyone else who is in any way connected with this site.

Many links on cancernewsnetwork.org lead to other sites. cancernewsnetwork.org does not sponsor, endorse or otherwise approve of the materials appearing in such sites. Nor is CancerNewsNetwork.org responsible for dead or misdirected links.

IF YOU NEED A LINK OR TEXT REMOVED FROM THIS PAGE PLEASE CONTACT cancernewsnetwork (at) live.com.
We will do our best to accommodate your request.



COPYRIGHT 2009 CANCERNEWSNETWORK | Privacy