InnoPran XL

This page contains recent news articles, when available, and an overview of InnoPran XL but does not offer medical advice. You should contact your physician with regard to any health issues or concerns.

Overview:

InnoPran XL (when available)

Pharmacology and use:
Propranolol, the prototype of the beta-adrenergic receptor antagonists, is a competitive, nonselective beta-blocker similar to nadolol without intrinsic sympathomimetic activity. Propanolol is a racemic compound; the l-isomer is responsible for adrenergic blocking activity. For the prophylaxis of migraine

Mechanism Of Action:
Like atenolol and metoprolol, propranolol competes with sympathomimetic neurotransmitters such as catecholamines for binding at beta(1)-adrenergic receptors in the heart and vascular smooth muscle, inhibiting sympathetic stimulation. This results in a reduction in resting heart rate, cardiac output, systolic and diastolic blood pressure, and reflex orthostatic hypotension. Higher doses of atenolol also competitively block beta(2)-adrenergic responses in the bronchial and vascular smooth muscles.

News Articles on Propranolol

GlaxoSmithKline to close Reliant HQ, lay off marketers - Apr 4, 2008
Reliant's other drugs include Dyna Circ and InnoPran XL to treat high blood pressure and Rythmol SR for abnormal heartbeats. Among the affected positions Medical Marketing and Media,

Eurand's formulations stack up at the FDA - 11 Mar 2008
...a timed and sustained-release dosage form of the beta-blocker propranolol developed for Reliant Pharmaceuticals and launched in the US as Innopran XL. In-PharmaTechnologist.com,

Brand Names/Synonyms:
InnoPran XL is also known by the following brand names and/or synonyms:
Angilol; Apsolol; Avlocardyl; Bedranol; Beprane; Berkolol; Beta-Neg; Beta-Propranolol; Beta-Tablinen; Beta-Timelets; Betachron; Betalong; Cardinol; Caridolol; Corpendol; Deralin; Dl-Propranolol Hydrochloride; Dociton; Duranol; Efektolol; Elbrol; Etalong; Euprovasin; Frekven; Inderal; Inderal La; Inderide; Indobloc; Innopran Xl; Intermigran; Kemi S; Obsidan; Oposim; Prano-Puren; Propanalol; Propanix; Propanolol; Prophylux; Propranalol; Propranolol; Propranolol Hcl; Propranolol Hcl Intensol; Propranolol Hydrochloride; Propranur; Proprasylyt; Pylapron; R,S-Propranolol Hydrochloride; Rapynogen; Reducor; Reducor Line; Sagittol; Servanolol; Sloprolol; Sumial; Tesnol

Drug Category:
InnoPran XL is categorized under the following by the FDA: Vasodilator Agents; Anti-anxiety Agents; Antihypertensive Agents; Antiarrhythmic Agents; Adrenergic Agents; ATC:C07AA05

Dosage Forms:
Tablets, I.V.

Absorption:
Propranolol is almost completely absorbed from the GI tract; however, plasma concentrations attained are quite variable among individuals

Interactions:
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Chemical IUPAC Name:
1-(1-methylethylamino)-3-naphthalen-1-yloxy-propan-2-ol

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