Inspra

This page contains recent news articles, when available, and an overview of Inspra but does not offer medical advice. You should contact your physician with regard to any health issues or concerns.


Overview:

Inspra
(when available)

Pharmacology and use:
Eplerenone, an aldosterone receptor antagonist similar to spironolactone, has been shown to produce sustained increases in plasma renin and serum aldosterone, consistent with inhibition of the negative regulatory feedback of aldosterone on renin secretion. The resulting increased plasma renin activity and aldosterone circulating levels do not overcome the effects of eplerenone. Eplerenone selectively binds to recombinant human mineralocorticoid receptors relative to its binding to recombinant human glucocorticoid, progesterone and androgen receptors. For improvement of survival of stable patients with left ventricular systolic dysfunction (ejection fraction <40%) and clinical evidence of congestive heart failure after an acute myocardial infarction.

Mechanism Of Action:
Eplerenone binds to the mineralocorticoid receptor and thereby blocks the binding of aldosterone (component of the renin-angiotensin-aldosterone-system, or RAAS). Aldosterone synthesis, which occurs primarily in the adrenal gland, is modulated by multiple factors, including angiotensin II and non-RAAS mediators such as adrenocorticotropic hormone (ACTH) and potassium. Aldosterone binds to mineralocorticoid receptors in both epithelial (e.g., kidney) and nonepithelial (e.g., heart, blood vessels, and brain) tissues and increases blood pressure through induction of sodium reabsorption and possibly other mechanisms.

News Articles on Eplerenone

Anti-smoking drugs in health basket  -  ‎Dec 23, 2009‎
Xarelto, Pradaxa and Soliris for hematology; Multaq, Inspra and Rqasilez for cardiovascular disease; Eraxis for infections; Avonex, Aricept, Exelon, ... Jerusalem Post

HEALTH CARE AND BLOOD PRESSURE  -  ‎Nov 11, 2009‎
Your doctor may also suggest nonthiazide diuretic drugs, such as spironolactone (Aldactone) or eplerenone (Inspra), which change the way your body absorbs ... The Cypress Times

Aldosterone Antagonists Recommended but Rarely Used  -  ‎Oct 20, 2009‎
That side effect can be avoided by using other drugs in the class, although the alternatives are branded drugs such as eplerenone (Inspra), Bhatt said. ... MedPage Today

Inspra.(Drug overview)  -  Dec 1, 2005
Inspra is prescribed to improve survival in patients who have congestive heart failure and left ventricular systolic dysfunction following a heart attack. ... Free with registration - PDR Family Guide to Prescription Drugs - AccessMyLibrary.com

Eplerenone | Life and style | BMJ Group  -  Jul 25, 2008
The brand name for eplerenone is Inspra. If you're already taking other treatments for heart failure (such as an ACE inhibitor, an angiotensin II blocker or ... guardian.co.uk

MP govt eyes greater foreign investment  -  Sep 27, 2005
GEI Hammon, Sonic Biochem, Hotline, Haylid Chemicals, JP Cement and CII-Bhopal chapter chairman, Vipin Mullick (Inspra) - who all would join the CM in Chicago. Business Standard

Australia OKs Inspra.(Inspra of Pfizer Inc. enters into Australia's …  -  Dec 19, 2005
Pfizer's Inspra (eplerenone) is to be added to Australia's Pharmaceutical Benefits Scheme from February 1, 2006. The government estimates that, ... Free with registration - Pharma Marketletter - AccessMyLibrary.com

… : REVISED: Early Use of Pfizer's Inspra(R) (Eplerenone) Significantl...  -  Aug 8, 2005
REVISED: Early Use of Pfizer's Inspra(R) (Eplerenone) Significantly Reduced Death Rates Among Heart Attack Patients With Reduced Heart Muscle Function and ... Pay-Per-View - PR Newswire Europe - HighBeam Research

Press Release: Early Use of Pfizer's Inspra(R) (Eplerenone) Significan...  -  Aug 8, 2005
Early Use of Pfizer's Inspra(R) (Eplerenone) Significantly Reduced Death Rates Among Heart Attack Patients With Reduced Heart Muscle Function and Signs of ... Pay-Per-View - PR Newswire Europe - HighBeam Research

Sandra Larson retires, was Dist. 64 nurse for 19 years  -  Jun 5, 2008
In recognition of her work, the Illinois Chapter of the National School of Public Relations Association (INSPRA) named her the winner of the Award of ... $2.95 - Park Ridge Herald-Advocate - NewsBank

Australia OKs Inspra.(Inspra of Pfizer Inc. enters into Australia's …  -  Dec 19, 2005
Pfizer's Inspra (eplerenone) is to be added to Australia's Pharmaceutical Benefits Scheme from February 1, 2006. The government estimates that, ... $4.95 - Pharma Marketletter - ECNext

Early use of Pfizer's Inspra reduces early cardiac death risk.(Brief...  -  Aug 22, 2005
According to data published in the August edition of the Journal of the American College of Cardiology, the use of Pfizer's aldosterone blocker Inspra ... Pay-Per-View - Pharma Marketletter - Factiva, from Dow Jones

Heart Failure; Aldosterone blocker recommended for patients with...  -  Jun 24, 2005
Zannad continued, "By adding the aldosterone blocker INSPRA to our current treatment ... INSPRA, an aldosterone blocker, works by inhibiting the effects of ... Pay-Per-View - Genomics & Genetics Weekly - Factiva, from Dow Jones

Finance: Promotional Productivity  -  Mar 1, 2006
Look at Inspra (eplerenone). Pfizer launched this drug in Q4 2003 and continues ... But Inspra is likely to remain a dog, despite any amount of promotion, ... PharmExec.com

Inspra non ritarda la disfunzione ventricolare sinistra nella stenosi...  -  Nov 27, 2008
Giovedì 27 Novembre 2008 - Uno studio ha valutato se l'antagonista selettivo del recettore dell'aldosterone, Eplerenone ( Inspra ) fosse in grado di ... XagenaSalute

Article: Deaths plunge for heart attack patients - Chicago Sun-Times...  -  May 2, 2007
Article: Pfizer Receives Approval to Market Inspra for Congestive ... ... Inspra, an ... Ephesus, heart attack patients with LVSD and heart failure on ... Pay-Per-View - Chicago Sun-Times - HighBeam Research

Avastin e Inspra obtienen los Premios Panorama 2005  -  Dec 15, 2005
Los fármacos bevacizumab y eplerenona, comercializados por Roche y Pfizer como Avastin e Inspra, respectivamente, han sido galardonados con los Premios ... doyma.es

SLV vil godkjenne billige legemidler  -  May 11, 2006
Inspra er et Pfizer-produkt. Ett års behandling med spironolakton koster 450 kroner, ... Inspra og Aldactone har ulik virkning og ulik dokumentasjon. ... Dagens Medisin

Press Release: New Data Examines the Effect of Adding a Statin to …  -  Nov 5, 2007
Article: Early Use of Pfizer's Inspra(R) (Eplerenone) Significantly ... ... Inspra ... morbidity in patients with heart failure. According ... ... Pay-Per-View - PR Newswire Europe - HighBeam Research

Press Release: Arginox Pharmaceuticals Reaches 50 Percent Enrollment …  -  May 17, 2006
Article: Early Use of Pfizer's Inspra(R) (Eplerenone) Significantly ... PR Newswire Europe; August 8, 2005 ; 700+ words ... ... early death in patients who ... Pay-Per-View - PR Newswire Europe - HighBeam Research

Herald News, The : classroomnotes  -  Oct 3, 2007
The INSPRA Communications Contest is an annual opportunity for school districts to submit publications, Web sites and campaigns for judging. ... $2.95 - Herald News - NewsBank

Press Release: Atrial Fibrillation Found to be Common in Patients...  -  Nov 7, 2008
Article: Early Use of Pfizer's Inspra(R) (Eplerenone) Significantly ... PR Newswire Europe; August 8, 2005 ; 700+ words ... ... early death in patients who ... Pay-Per-View - PR Newswire Europe - HighBeam Research

Press Release: New Research Shows ACTOS(R) (pioglitazone HCI) is …  -  Sep 19, 2007
Article: Early Use of Pfizer's Inspra(R) (Eplerenone) Significantly ... PR Newswire Europe; August 8, 2005 ; 700+ words ... ... early death in patients who ... Pay-Per-View - PR Newswire Europe - HighBeam Research

Press Release: New Lifeline for Elderly Heart Attack Patients. - PR …  -  Apr 3, 2006
Article: Early Use of Pfizer's Inspra(R) (Eplerenone) Significantly ... PR Newswire Europe; August 8, 2005 ; 700+ words ... ... systolic dysfunction [LVSD]) ... Pay-Per-View - PR Newswire Europe - HighBeam Research

Getting a head start Eighth-graders visit Mundelein High for a...  -  May 9, 2007
The annual program is sponsored by the Illinois Chapter of the National School Public Relations Association (INSPRA). The awards luncheon will be at the ... $4.95 - Daily Herald - ECNext

Press Release: European Commission Expands Indication for PLAVIX(R) …  -  Sep 7, 2006
Article: Early Use of Pfizer's Inspra(R) (Eplerenone) Significantly ... PR Newswire Europe; August 8, 2005 ; 700+ words ... ... early death in patients who ... Pay-Per-View - PR Newswire Europe - HighBeam Research

Press Release: Medtronic Announces Key Activities at Cardiostim 2008....  -  Jun 16, 2008
Article: Early Use of Pfizer's Inspra(R) (Eplerenone) Significantly ... PR Newswire Europe; August 8, 2005 ; 700+ words ... ... systolic dysfunction [LVSD]) ... Pay-Per-View - PR Newswire Europe - HighBeam Research

Fed: Heart drug to be added to PBS from February | Article from AAP …  -  Dec 7, 2005
From February 1, Inspra - used to treat thousands of Australians with heart disease ... "Inspra is being listed for patients who have heart failure and left ... Pay-Per-View - AAP General News - HighBeam Research

New PBS listings  -  Feb 14, 2006
Inspra will be available for patients who have heart failure and left ventricular ... It is estimated Inspra will help about 5000 people in the first full ... $2.50 - Northern Miner - News Limited Australia

Press Release: Brigham and Women's Cardiac Group Finds Enoxaparin …  -  Mar 14, 2006
Article: Early Use of Pfizer's Inspra(R) (Eplerenone) Significantly ... PR Newswire Europe; August 8, 2005 ; 700+ words ... ... early death in patients who ... Pay-Per-View - PR Newswire Europe - HighBeam Research

Press Release: Arginox Enrolls First European Patients in Phase III...  -  Jul 26, 2005
Article: Early Use of Pfizer's Inspra(R) (Eplerenone) Significantly ... PR Newswire Europe; August 8, 2005 ; 700+ words ... ... early death in patients who ... Pay-Per-View - PR Newswire Europe - HighBeam Research

Press Release: Takeda's Actos(R) (pioglitazone) Helps to Prevent...  -  Nov 18, 2005
Article: Early Use of Pfizer's Inspra(R) (Eplerenone) Significantly ... PR Newswire Europe; August 8, 2005 ; 700+ words ... ... early death in patients who ... Pay-Per-View - PR Newswire Europe - HighBeam Research

Thousands of UK Heart Failure Deaths Could be Prevented, According to...  -  Feb 4, 2005
Article: Early Use of Pfizer's Inspra(R) (Eplerenone) Significantly ... PR Newswire Europe; August 8, 2005 ; 700+ words ... ... systolic dysfunction [LVSD]) ... Pay-Per-View - PR Newswire Europe - HighBeam Research

Brooks Middle School's students of the month are:  -  Oct 10, 2007
The INSPRA Communications Contest is an annual opportunity for school districts to submit publications, Web sites and campaigns for judging. ... $2.95 - Herald News - NewsBank

Press Release: Clopidogrel Before Angioplasty Cuts in Half Risk of...  -  Sep 4, 2005
Article: Early Use of Pfizer's Inspra(R) (Eplerenone) Significantly ... PR Newswire Europe; August 8, 2005 ; 700+ words ... ... early death in patients who ... Pay-Per-View - PR Newswire Europe - HighBeam Research

Article: Debate renewed: diabetes drug ups heart risk.(This Week)( …  -  Sep 15, 2007
Article: Early Use of Pfizer's Inspra(R) (Eplerenone) Significantly ... ... Article: Pfizer Receives Approval to Market Inspra for Congestive ... ... Pay-Per-View - Science News - HighBeam Research

Weber Shandwick wins Lipitor account.(PUBLIC RELATIONS)(contracts …  -  Dec 1, 2006
Pfizer has assigned the PR for the launch of its congestive heart failure treatment Inspra to Weber Shandwick. Inspra will launch in early 2004. ... Pay-Per-View - Medical Marketing & Media - HighBeam Research

For your health's sake, shake the salt habit | Article from The...  -  Apr 26, 2005
The Record (Bergen County, NJ); October 1, 2002 ; 632 words ... ... patients showed Inspra lowered blood pressure alone and with other blood pressure ... Pay-Per-View - The Record - HighBeam Research

Press Release: Published Study Shows Benefits of Revatio (Sildenafil ...  -  Nov 16, 2005
Article: Pfizer Receives Approval to Market Inspra for Congestive Heart ... ... Inspra is contraindicated in patients with serum potassium ... of this ... Pay-Per-View - PR Newswire - HighBeam Research

Article: Pfizer: Celebrex Causes No Increased Risk - AP Online | …  -  Feb 5, 2005
Article: Pfizer Receives Approval to Market Inspra for Congestive . ... Inspra, an aldosterone ... been injured from a heart attack or high blood pressure . ... Pay-Per-View - AP Online - HighBeam Research

Press Release: New ESC Heart Failure Guidelines Recommend Addition …  -  May 24, 2005
Pfizer's INSPRA(R) (eplerenone) has the potential to save more lives ... Article: Pfizer Receives Approval to Market Inspra for Congestive ... ... Pay-Per-View - PR Newswire Europe - HighBeam Research

Article: Inpatient mortality from heart attack and heart failure...  -  Jan 1, 2008
Article: Early Use of Pfizer's Inspra(R) (Eplerenone) Significantly ... ... Article: Pfizer Receives Approval to Market Inspra for Congestive ... ... Pay-Per-View - Internal Medicine News - HighBeam Research

Dilated cardiomyopathy  -  Sep 18, 2007
These drugs include spironolactone (Aldactone) and eplerenone (Inspra). They are primarily potassium-sparing diuretics, but they have additional properties ... CNN International

Press Release: Head-to-Head Study Showed Prasugrel Statistically …  -  Aug 21, 2008
INSPRA(R) reduced the risk of death by 15%, cardiovascular death by 17%, ... Article: Early Use of Pfizer's Inspra(R) (Eplerenone) Significantly ... ... Pay-Per-View - PR Newswire Europe - HighBeam Research

Conns syndrom  -  Aug 23, 2005
Det finst to typar aldosteronantagonistar, spironolacton (Spirix og Aldactone) og eplerenon (Inspra). Inspra er eit nokså nytt medikament som ein sjølvsagt ... Lommelegen.no

Press Release: InterCure Supports AHA Endorsement of Home Blood …  -  May 29, 2008
Article: FDA Approves INSPRA(TM), An Aldosterone Blocker for the Treatment ... ... Of those, 73 percent ... control of their high blood pressure, INSPRA ... Pay-Per-View - PR Newswire - HighBeam Research

Article: Diabetes drug lowers some cardiac risks, but not heart...  -  Dec 1, 2007
Article: Early Use of Pfizer's Inspra(R) (Eplerenone) Significantly ... ... Article: Pfizer Receives Approval to Market Inspra for Congestive ... ... Pay-Per-View - Healthy Years - HighBeam Research

Article: "America's best cardiac hospitals"--many others are just as...  -  Sep 1, 2006
Article: Early Use of Pfizer's Inspra(R) (Eplerenone) Significantly ... ... Article: Treatment With INSPRA(TM) Resulted in Significantly Fewer Deaths ... ... Pay-Per-View - HealthFacts - HighBeam Research

Research and Markets: Cardiovascular Market Outlook to 2009: Key …  -  Mar 16, 2005
Key findings of the report - Pfizer's growth will be adversely affected by the continuing disappointing performance of recent launches Inspra and Caduet as ... $4.95 - PR Newswire - ECNext

Press Release: New Benefit Shown for Patients With Damaged Hearts. - ...  -  Jul 26, 2005
Article: Early Use of Pfizer's Inspra(R) (Eplerenone) Significantly ... PR Newswire Europe; August 8, 2005 ; 700+ words ... ... Cardiology (JACC). ... Pay-Per-View - PR Newswire Europe - HighBeam Research

eplerenone Pfizer marketed, Netherlands (heart failure).(Pharmaceutica...  -  Mar 14, 2005
In November 2004 Pfizer launched eplerenone (INSPRA), a selective aldosterone receptor ... eplerenone, epoxymexrenone, CGP 30083, SC 66110, INSPRA, C1D, ... Pay-Per-View - R & D Focus Drug News - Factiva, from Dow Jones

… RESEARCH) - Nutraceuticals World | HighBeam Research - FREE trial  -  May 1, 2007
Article: Early Use of Pfizer's Inspra(R) (Eplerenone) Significantly ... ... Article: Pfizer Receives Approval to Market Inspra for Congestive ... ... Pay-Per-View - Nutraceuticals World - HighBeam Research

Primer cara a cara parlamentario de Zapatero y Rajoy tras el congreso...  -  Jun 26, 2008
Este Gobierno me inspra poca confianza. No te empeñes Mariano, los socialistas son unos negados para la economia. Ya nos lo han demostrado a lo largo de la ... Diario de Navarra

High blood pressure (hypertension)  -  Aug 7, 2008
Your doctor may also suggest nonthiazide diuretic drugs, such as spironolactone (Aldactone) or eplerenone (Inspra), which change the way your body absorbs ... CNN International

Article: Dutch treat: Eating chocolate could be good for you - The...  -  Feb 28, 2006
0000 Pharmacia gets FDA approval for blood pressure pill -- Merger expected before launch ... approval of Inspra, a treatment for high blood pressure. ... Pay-Per-View - The Record - HighBeam Research

Maker of Heart Drug Intended for Blacks Bases Price on Patients'...  -  Jul 8, 2005
...based on the costs of heart-failure treatments currently on the market: Coreg by Glaxo Smith Kline and Inspra by Pfizer. At $1.80 a pill, however, ... New York Times

Pfizer's Funk  -  Feb 28, 2005
...(Ever heard of Caduet or Inspra?) The diseases Pfizer and others now chase are harder to defeat with a one-pill, mass-market solution. ... BusinessWeek

The blood-pressure self-check | Article from The Record (Bergen...  -  Dec 9, 2008
0000 Pharmacia gets FDA approval for blood pressure pill -- Merger expected before launch ... approval of Inspra, a treatment for high blood pressure. ... Pay-Per-View - The Record - HighBeam Research

Article: Serious fetal risk seen from hypertension drug - The Record...  -  Jun 8, 2006
0000 Pharmacia gets FDA approval for blood pressure pill -- Merger expected before launch ... approval of Inspra, a treatment for high blood pressure. ... Pay-Per-View - The Record - HighBeam Research

Why Are So Many Pills Used To Treat Heart Failure?  -  May 24, 2008
These drugs, including spironolactone (Aldactone) and eplerenone (Inspra), are primarily potassium-sparing diuretics that may or may not be the part of the ... Pay-Per-View - Tampa Tribune - ProQuest Archiver

Drug reduces risk of a heart problem | Article from The Record...  -  Apr 24, 2007
0000 Pharmacia gets FDA approval for blood pressure pill -- Merger expected before launch ... approval of Inspra, a treatment for high blood pressure. ... Pay-Per-View - The Record - HighBeam Research

Sun avoidance tops survey.(Clinical Rounds) | Article from OB GYN...  -  Apr 1, 2005
Article: New & Approved: Inspra Clozaril. (Clinical Rounds). ... Inspra (eplerenone, Pharmacia) An aldosterone blocker for treating hypertension, ... Pay-Per-View - OB GYN News - HighBeam Research

Press Release: Study Shows Advanced Heart Failure Patients Improve …  -  Jun 6, 2005
Article: Early Use of Pfizer's Inspra(R) (Eplerenone) Significantly ... PR Newswire Europe; August 8, 2005 ; 700+ words ... ... systolic dysfunction [LVSD]) ... Pay-Per-View - PR Newswire Europe - HighBeam Research

Feds to evaluate disease Tx.(Clinical Rounds) | Article from OB GYN …  -  Feb 15, 2005
Article: New & Approved: Inspra Clozaril. (Clinical Rounds). ... Inspra (eplerenone, Pharmacia) An aldosterone blocker for treating hypertension, ... Pay-Per-View - OB GYN News - HighBeam Research

Article: Novartis gets FDA approval for heart attack treatment;...  -  Aug 31, 2005
Article: Early Use of Pfizer's Inspra(R) (Eplerenone) Significantly ... ... Article: Treatment With INSPRA(TM) Resulted in Significantly Fewer Deaths ... ... Pay-Per-View - Transplant News - HighBeam Research

Press Release: FDA Approves Diovan(R) (Valsartan) to Reduce …  -  Aug 3, 2005
Article: Early Use of Pfizer's Inspra(R) (Eplerenone) Significantly ... ... Article: Treatment With INSPRA(TM) Resulted in Significantly Fewer Deaths ... ... Pay-Per-View - PR Newswire - HighBeam Research

Article: FINDINGS - The Washington Post | HighBeam Research - FREE …  -  Aug 30, 2005
Article: Early Use of Pfizer's Inspra(R) (Eplerenone) Significantly ... PR Newswire Europe; August 8, 2005 ; 700+ words . ... Pay-Per-View - Washington Post - HighBeam Research

THE PRESSURE COOKERS | Article from The Record (Bergen County, …  -  Jul 25, 2006
0000 Pharmacia gets FDA approval for blood pressure pill -- Merger expected before launch ... approval of Inspra, a treatment for high blood pressure. ... Pay-Per-View - The Record - HighBeam Research

Blood pressure, cholesterol drug use rises | Article from The Record...  -  Oct 30, 2007
0000 Pharmacia gets FDA approval for blood pressure pill -- Merger expected before launch ... approval of Inspra, a treatment for high blood pressure. ... Pay-Per-View - The Record - HighBeam Research

NATIONAL BRIEFS | Article from The Record (Bergen County, NJ) | …  -  Jan 22, 2008
0000 Pharmacia gets FDA approval for blood pressure pill -- Merger expected before launch ... approval of Inspra, a treatment for high blood pressure. ... Pay-Per-View - The Record - HighBeam Research

Beware of drug interactions | Article from The Record (Bergen County,...  -  Jan 10, 2008
0000 Pharmacia gets FDA approval for blood pressure pill -- Merger expected before launch ... approval of Inspra, a treatment for high blood pressure. ... Pay-Per-View - The Record - HighBeam Research

Taking a pill at bedtime may be healthier | Article from The Record (...  -  Dec 18, 2007
0000 Pharmacia gets FDA approval for blood pressure pill -- Merger expected before launch ... approval of Inspra, a treatment for high blood pressure. ... Pay-Per-View - The Record - HighBeam Research

Moms' low-allergen diets could calm colicky babies | Article from The...  -  Nov 22, 2005
0000 Pharmacia gets FDA approval for blood pressure pill -- Merger expected before launch ... approval of Inspra, a treatment for high blood pressure. ... Pay-Per-View - The Record - HighBeam Research

Third of teens would fail treadmill test, study says | Article from...  -  Dec 21, 2005
0000 Pharmacia gets FDA approval for blood pressure pill -- Merger expected before launch ... approval of Inspra, a treatment for high blood pressure. ... Pay-Per-View - The Record - HighBeam Research

Article: Commentator to give back some money he took - Chicago Sun- …  -  Oct 3, 2005
2004 ; 697 words ... ... details of the federal No Child Left Behind Act. Parents ... the National School Public Relations Association, or INSPRA . ... Pay-Per-View - Chicago Sun-Times - HighBeam Research

Non-aspirin painkillers tied to blood pressure risk in women |...  -  Aug 16, 2005
0000 Pharmacia gets FDA approval for blood pressure pill -- Merger expected before launch ... approval of Inspra, a treatment for high blood pressure. ... Pay-Per-View - The Record - HighBeam Research

Driver cellphone use increases accident risk | Article from The...  -  Aug 2, 2005
0000 Pharmacia gets FDA approval for blood pressure pill -- Merger expected before launch ... approval of Inspra, a treatment for high blood pressure. ... Pay-Per-View - The Record - HighBeam Research

Article: Therapy may help resolve sleeplessness problem - The Record...  -  Dec 20, 2005
0000 Pharmacia gets FDA approval for blood pressure pill -- Merger expected before launch ... approval of Inspra, a treatment for high blood pressure. ... Pay-Per-View - The Record - HighBeam Research

New Pfizer CEO begins tackling drugmaker's mounting challenges.  -  Aug 17, 2006
Sales of several recently launched drugs, including Inspra for heart failure and Caduet for both high cholesterol and high blood pressure have been ... Free with registration - America's Intelligence Wire - AccessMyLibrary.com

Nombres, nombres y... nombres  -  Feb 20, 2008
De los nuevos está el Champix para eliminar la adicción al tabaco, el Inspra para insuficiencia cardiaca y están en el tintero para su aprobación aquí el ... El Universal - El Universal (México)

Pfizer's new chief enters under the gun  -  Sep 3, 2006
Sales of several recently launched drugs, including Inspra for heart failure and Caduet for high cholesterol and high blood pressure have been disappointing ... sptimes.com

Ny behandling minskar dödligheten hos hjärtsviktspatienter  -  Mar 10, 2005
Den visar att dödligheten hos dessa patienter minskar med 15 % om behandling med en aldosteron receptorhämmare kallad Inspra, sätt in direkt. ... Sveriges Radio

辉瑞制è?¯å…¬å?¸å¼ºåŒ–在日本的开å?‘  -  Mar 21, 2005
...抗霉�感染的�物Prodif(fosfluconazole)。2005年�能在日本获得批准的产�有全身 性抗真��物Vfend(voriconazole),Inspra(eplerenone)以�Detrol(tolterodine)。 ... 中金在线

Aldosterone antagonists treat tough HT.(Hypertension)(Disease/Disorder...  -  Jul 15, 2006
He is a consultant to Pfizer Inc., which markets eplerenone (Inspra). Spironolactone is a generic drug. Dr. Calhoun said that in his experience, ... Free with registration - Family Practice News - AccessMyLibrary.com

St dipressed  -  Oct 30, 2007
If so, you might ask her doctor to either switch her to a potassium-sparing diuretic (eg, dyrenium, spironolactone, or Inspra, which is a new drug which ... HealthCentral.com

Longtime LW board member steps down  -  Nov 4, 2008
Fagan has received a number of awards for his service to the board including the INSPRA [Illinois Chapter National School Public Relations Association] ... New Lenox Patriot

Pfizer Fourth-Quarter and Full-Year 2005 Financial Results Reflect …  -  Jan 19, 2006
The combined sales of these products (Inspra, Caduet, Olmetec, Macugen, Revatio, Zmax, and Lyrica) generated $284 million in fourth-quarter 2005 revenue and ... Free with registration - PR Newswire - AccessMyLibrary.com

Research and Markets: ARBs Continue To Be The Only Class of …  -  Feb 15, 2005
Pfizer's growth will be adversely affected by the continuing disappointing performance of recent launches Inspra and Caduet as well as the expiry of patents ... Free with registration - Business Wire - AccessMyLibrary.com

Mayo Clinic expertise  -  Jan 3, 2008
These drugs include spironolactone (Aldactone) and eplerenone (Inspra). They're primarily potassium-sparing diuretics, but they have additional properties ... MayoClinic.com

MILESTONES  -  Apr 4, 2005
Kurt Daniel, D.O., an internal medicine specialist at Wake Forest University Baptist Medical Center, has been selected to the Inspra Young Investigator ... Pay-Per-View - Winston-Salem Journal - ProQuest Archiver

Daily Southtown (Chicago, IL)  -  Oct 22, 2007
The INSPRA Communications Contest is an annual opportunity for school districts to submit publications, Web sites and campaigns for judging. ... $2.95 - Daily Southtown - NewsBank

SCHOOL DIGEST  -  May 17, 2007
The award presentation will be made Friday (May 18) in Bolingbrook at the annual INSPRA awards luncheon. Dick Johnson of NBC News will serve as master of ... $2.95 - Elk Grove Times - NewsBank

Waiting for the sun Hawthorn North students go solar for energy …  -  Oct 11, 2006
District 95 also received the INSPRA Golden Achievement Award of Merit for its annual Staff Recognition Program, which honors staff members for specific ... $4.95 - Daily Herald - ECNext

Personnel; Philip Needleman, August Watanabe named to drug …  -  Apr 15, 2005
...as chief scientist and chairman of research and development, overseeing the commercialization of drugs including Celebrex, Bextra, Dynastat and Inspra. ... Pay-Per-View - Drug Week - Factiva, from Dow Jones

Press Release: PFIZER INC - Regulatory Approval. - PR Newswire UK …  -  Feb 2, 2006
The combined sales of these products (Inspra, Caduet, Olmetec, Macugen, Revatio, Zmax, and Lyrica) generated $284 million in fourth-quarter 2005 revenue and ... Pay-Per-View - PR Newswire UK Disclose - HighBeam Research

Development of highly innovative drugs continues to decline.  -  Nov 1, 2005
Specific medications evaluated with a safety advantage were ezetimibe (Zetia, Merck/Schering-Plough), eplerenone (Inspra, Pfizer), and nitazoxanide (Alinia, ... $9.94 - Formulary - Alacra Store

Hypertension: upping the ante.(CLINICAL TWISTERS Rx)(Heart failure)( …  -  Sep 17, 2007
Since aldosterone blockers are recommended in HE treatment with spironolactone 25 mg or eplerenone (Inspra, Pfizer) 25 mg daily should be considered. ... $4.95 - Drug Topics - ECNext

Press Release: Finalists Announced For the Fourth Annual …  -  May 11, 2005
Inc.: Tarceva Pfizer, Inc.: Inspra Outstanding Biologic Drug Product Award Genentech Inc.: Avastin Imclone Systems, Inc & Bristol-Myers Squibb Co. ... Pay-Per-View - PR Newswire - HighBeam Research

Personnel; Philip Needleman, August Watanabe named to drug …  -  Apr 16, 2005
...as chief scientist and chairman of research and development, overseeing the commercialization of drugs including Celebrex, Bextra, Dynastat and Inspra. ... Pay-Per-View - Obesity, Fitness & Wellness Week - Factiva, from Dow Jones

Unstable angina, non-STEMI get new guidelines.(Cardiovascular …  -  Sep 1, 2007
A new addition in the guidelines is use of an aldosterone receptor blocker, either spironolactone or eplerenone (Inspra) for patients with a left ... $4.95 - Internal Medicine News - ECNext

Press Release: The Lancet Publishes Vasogen's ACCLAIM Results. - PR …  -  Jan 18, 2008
Article: Early Use of Pfizer's Inspra(R) (Eplerenone) Significantly ... PR Newswire Europe; August 8, 2005 ; 700+ words ... ... survival and morbidity in ... Pay-Per-View - PR Newswire Europe - HighBeam Research

Press Release: Kalypsys Announces Appointment of CEO; John McKearn …  -  Mar 22, 2005
...products developed successfully under his management, including the blockbuster inflammation drugs Celebrex(R) and Bextra(R) as well as Inspra(R). ... Pay-Per-View - PR Newswire - HighBeam Research

Personnel; Philip Needleman, August Watanabe named to drug …  -  Apr 11, 2005
...as chief scientist and chairman of research and development, overseeing the commercialization of drugs including Celebrex, Bextra, Dynastat and Inspra. ... Pay-Per-View - Biotech Business Week - Factiva, from Dow Jones

Brand Names/Synonyms:
Inspra is also known by the following brand names and/or synonymsCgp 30083; Eplerenone; Eplerenone [Usan]; Epoxymexrenone; INSPRA; Inspra; SC-66110

Drug Category:
Inspra is categorized under the following by the FDA: Antihypertensive Agents; ATC:C03DA04

Dosage Forms:
TABLET (film-coated - 25, 50 mg)

Absorption:
The absolute bioavailability of eplerenone is unknown.

Interactions:
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Chemical IUPAC Name:
Not Available





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