Interferon alfa-2b

This page contains recent news articles, when available, and an overview of Interferon alfa-2b but does not offer medical advice. You should contact your physician with regard to any health issues or concerns.


Overview:

Interferon alfa-2b
(when available)

Pharmacology and use:
Upregulates the expression of MHC I proteins, allowing for increased presentation of peptides derived from viral antigens. This enhances the activation of CD8+ T cells that are the precursors for cytotoxic T lymphocytes (CTLs) and makes the macrophage a better target for CTL-mediated killing. Interferon alpha also induce the synthesis of several key antiviral mediators, including 2'-5' oligoadenylate synthetase (2'-5' A synthetase) and protein kinase R. For treatment of hairy cell leukemia, malignant melanoma, and AIDS-related Kaposi's sarcoma

Mechanism Of Action:
Interferon alpha binds to type I interferon receptors (IFNAR1 and IFNAR2c) which upon dimerization activate two Jak (Janus kinase) tyrosine kinases (Jak1 and Tyk2). These transphosphorylate themselves and phosphorylate the receptors. The phosphorylated INFAR receptors then bind to Stat1 and Stat2 (signal transducers and activators of transcription)which dimerize and activate multiple (~100) immunomodulatory and antiviral proteins. Interferon alpha binds less stably to type I interferon receptors than interferon beta.

News Articles on Interferon alfa-2b

Assessment of Physical Illness by Mental Health Clinicians During Intake Visits  -  ‎Dec 31, 2009‎
Schafer A, Wissmann S, et al: Neurocognitive changes in patients with hepatitis C receiving interferon alfa-2b and ribavirin. ... Psychiatric Services (subscription)

Apotheker muss keinen Schadenersatz zahlen  -  ‎Dec 23, 2009‎
...einer nicht existierenden Internistin dazu gebracht, ihm mehrfach das Präparat Intron A (rekombinantes Interferon alfa-2b) zu verordnen. ... apotheke-adhoc

Apotheker soll für gefälschte Rezepte zahlen  -  ‎Dec 17, 2009‎
Internistin dazu gebracht, ihm von Oktober 1999 bis April 2000 mehrfach das Präparat Intron A (rekombinantes Interferon alfa-2b) zu verordnen. ... apotheke-adhoc

Low-dose Interferon-alfa Does Not Improve Outcomes of Patients with Renal Cell ...  -  ‎Nov 4, 2009‎
...[2] Phase II trial of sorafenib plus interferon alfa-2b as first-or second-line therapy in patients with metastatic renal cell cancer. ... Cancer Consultants

AASLD: HCV Response Linked Strongly to Gene Variant  -  ‎Nov 5, 2009‎
Schering-Plough, which sells pegylated interferon-alfa-2b (PEGIntron), owns commercial rights to develop the genotype test. A spokesman said the company was ... MedPage Today

AASLD: Once-Daily HCV Protease Inhibitors Show Early Promise  -  ‎Nov 3, 2009‎
At least 85% of patients adding narlaprevir (formerly called SCH 900518) to pegylated interferon-alfa-2b (PEGIntron) and ribavirin (Rebetol) after four ... MedPage Today

Valeant Pharmaceuticals Highlights Taribavirin Phase IIb End of Study Data ...  -  ‎Nov 3, 2009‎
The control group was administered weight-based dose ribavirin (800/1000/1200/1400mg daily) and pegylated interferon alfa-2b. Overall treatment duration was ... Reuters

FDA rejects expanded use of Pegintron  -  ‎Nov 2, 2009‎
...a complete response letter – an FDA notice of rejection – for Pegintron (pegylated interferon alfa-2b) as a treatment for stage 3 malignant melanoma. ... Drug Store News (blog)

An Infectious Problem for the Brain  -  ‎Oct 22, 2009‎
In 2001, Miller and colleagues reported that nearly half of people who take one such drug, interferon alfa-2b, become depressed within 12 weeks. ... Science Magazine (blog)

Schering-Plough receives FDA complete response letter regarding PEGINTRON  -  ‎Oct 31, 2009‎
PEGINTRON® (pegylated interferon alfa-2b) for the adjuvant treatment of patients with stage III malignant melanoma after complete lymphadenectomy. ... News-Medical.net

Low doses of interferon alfa-2b after surgery  -  Sep 1, 2008
No. Low doses of interferon alfa-2b after surgery probably won't help you live longer if you have a melanoma. But if you have this treatment it may take ... guardian.co.uk

Long-Term Pegylated Interferon Alfa-2b Therapy in Stage III Melanoma ...  -  Jul 11, 2008
KENILWORTH, NJ, July 11 /PRNewswire-FirstCall/ -- Today, Schering-Plough and the EORTC announced that long-term treatment with pegylated interferon alfa-2b ... RedOrbit

Adjuvant therapy with high-dose interferon 2b in patients with high...  -  Jul 20, 2007
In 2007, a predictably curative therapy for metastatic melanoma has yet to be identified, but we have begun to understand the immunosuppressive impact of ... Nature.com

… Therapy; Positive phase-II data reported on pegylated interferon...  -  Jul 26, 2005
2005 JUL 26 - (NewsRx.com) -- Positive results were reported from a phase-II study of pegylated interferon alfa-2b for patients with metastatic renal cell ... Pay-Per-View - Life Science Weekly - Factiva, from Dow Jones

… AND INTERFERON ALFA-2B, RECOMBINANT (Systemic).(Drug …  -  May 1, 2006
Ribavirin and interferon alfa-2b (rye -- ba -- VYE-rin and in -- ter -- FEER -- on AL -- fa) combination is used to treat a viral liver infection known as ... Free with registration - USP DI-Volume II, Advice for the... - AccessMyLibrary.com

RIBAVIRIN AND INTERFERON ALFA-2B, RECOMBINANT (Systemic).  -  Feb 1, 2006
Ribavirin and interferon alfa-2b (rye -- ba -- VYE-rin and in -- ter -- FEER -- on AL -- fa) combination is used to treat a viral liver infection known as ... Free with registration - USP DI-Volume II, Advice for the... - AccessMyLibrary.com

RIBAVIRIN AND INTERFERON ALFA-2B (Oral route, Injection route) - rye …  -  May 1, 2007
Ribavirin and interferon alfa-2b combination is used to treat a viral liver infection known as hepatitis C infection. Ribavirin is taken by mouth and ... Free with registration - USP DI-Volume II, Advice for the... - AccessMyLibrary.com

Alcoholic Liver Disease Treatment - Alcoholic Liver Disease Health …  -  Dec 12, 2008
The only treatment for alcoholic cirrhosis is to stop drinking. Individuals with alcoholic cirrhosis are typically malnourished and require increased ... New York Times

EU Label Change for Intron A (Interferon Alfa-2b) Incorporates Long...  -  Apr 26, 2006
KENILWORTH, NJ -- April 26, 2006 -- Schering-Plough Corporation today reported that the European Commission has adopted changes to the European Union (EU) ... DG News

Long-Term Pegylated Interferon Alfa-2b Therapy in Stage III Melanoma ...  -  Jun 2, 2007
CHICAGO, June 2 /PRNewswire-FirstCall/ -- Long-term treatment with pegylated interferon alfa-2b in stage III melanoma had a significant and sustained impact ... Free with registration - PR Newswire - AccessMyLibrary.com

Article: New drugs, new hope; Medications offer options for kidney...  -  Jun 19, 2006
New drugs, new hope; Medications offer options for kidney cancer puzzle ... find The Milwaukee Journal Sentinel articles. For more than a decade, ... Pay-Per-View - Milwaukee Journal Sentinel - HighBeam Research

Trial Shows Long-Term Pegylated Interferon Alfa-2b Therapy Helps in …  -  Jun 5, 2007
Long-term treatment with pegylated interferon alfa-2b in Stage III melanoma had a significant and sustained impact on relapse-free survival (RFS), ... FDA news - FDA news (subscription)

… Change for INTRON(R) A (interferon Alfa-2b) Incorporates Long-Term...  -  Apr 26, 2006
EU Label Change for INTRON(R) A (interferon Alfa-2b) Incorporates Long-Term Efficacy Data in Patients with Chronic Hepatitis C. from PR Newswire. Pay-Per-View - PR Newswire - HighBeam Research

Cancer Therapy; Intermediate doses of interferon alfa 2b did not...  -  Nov 29, 2005
2005 NOV 29 - (NewsRx.com) -- Scientists observed that intermediate doses of interferon alfa 2b did not improve the outcome for patients with stage IIb/III ... Pay-Per-View - Life Science Weekly - Factiva, from Dow Jones

Pegylated interferon alfa-2b a possible adjuvant treatment option for...  -  Aug 7, 2008
Adjuvant pegylated interferon alfa-2b improved the recurrence-free survival in patients with stage III melanoma. Researchers for the EORTC Melanoma Group ... HemOncToday

… Efficacy Shown For Pegylated Interferon Alfa-2b, Pegylated Interfero...  -  Nov 7, 2007
By Maria Bishop. BOSTON, MA -- November 7, 2007 -- There is no difference in sustained viral response (SVR) rates between patients with hepatitis C virus ... DG News

… system, transdermal BIPHASIX interferon alfa-2b Helix BioPharma...  -  Jun 20, 2005
Helix BioPharma announced on 2 June 2005 that it has opened two additional German clinical sites for the phase II trial of its topical interferon alfa-2b. ... Pay-Per-View - R & D Focus Drug News - Factiva, from Dow Jones

Press Release: Long-Term Pegylated Interferon Alfa-2b Therapy in...  -  Jul 11, 2008
Long-Term Pegylated Interferon Alfa-2b Therapy in Stage III Melanoma Demonstrated Significant and Sustained Impact on Relapse-Free Survival. from PR ... Pay-Per-View - PR Newswire - HighBeam Research

drug delivery system, transdermal BIPHASIX interferon alfa-2b Helix …  -  Sep 19, 2005
Helix BioPharma announced on 12 September 2005 that it has received approval from the Swedish Medical Products Agency to conduct a multicenter, randomized, ... Pay-Per-View - R & D Focus Drug News - Factiva, from Dow Jones

Phase II Trial of Sorafenib Plus Interferon Alfa-2b as First- or...  -  Oct 16, 2007
Between November 2004 and October 2006, 40 patients at two sites were enrolled onto a phase II trial of sorafenib plus IFN-alpha-2b. ... UroToday International Journal

Press Release: Long-Term Pegylated Interferon Alfa-2b Therapy in...  -  Jun 2, 2007
Long-Term Pegylated Interferon Alfa-2b Therapy in Stage III Melanoma Demonstrated Significant and Sustained Impact on Relapse-Free Survival. from PR ... Pay-Per-View - PR Newswire - HighBeam Research

Bartlett HIV/AIDS Review: March 15, 2005: HIV and Hepatitis  -  Mar 15, 2005
Carrat F, Bani-Sadr F, Pol S, et al. Pegylated interferon alfa-2b vs. standard interferon alfa-2b, plus ribavirin, for chronic hepatitis C in HIV-infected ... Medscape

… Change for INTRON(R) A (interferon alfa-2b) Incorporates Long-Term...  -  Apr 26, 2006
EU Label Change for INTRON(R) A (interferon alfa-2b) Incorporates Long-Term Efficacy Data in Patients with Chronic Hepatitis C. from PR Newswire Europe. Pay-Per-View - PR Newswire Europe - HighBeam Research

Hepatitis A Medications - Hepatitis A Health Information - NY Times …  -  Dec 5, 2008
These drugs block the replication of hepatitits B in the body. They may also help prevent the development of progressive liver disease (cirrhosis and liver ... New York Times

Sorafenib with Interferon Alfa-2b as First-Line Treatment of Advanced...  -  Oct 15, 2007
This phase II study evaluated the activity of combined treatment with interferon alfa-2b and sorafenib, a Raf and multiple receptor tyrosine kinase ... UroToday International Journal

Hepatitis C Medications - Hepatitis C Health Information - NY Times …  -  Feb 20, 2008
These drugs block the replication of hepatitits B in the body. They may also help prevent the development of progressive liver disease (cirrhosis and liver ... New York Times

High-risk melanoma with nodal involvement in a young woman  -  Oct 30, 2005
Background An 18-year-old female presented to her General Practitioner with a bleeding mole on her back. The mole had been present since childhood but had ... Nature.com

PegIntron(R) (peginterferon alfa-2b) Clinical Studies in Hepatitis to...  -  Apr 7, 2005
Schering-Plough's PegIntron(R) (peginterferon alfa-2b), used in combination therapy with Rebetol(R) (ribavirin), is proven effective in treating patients ... Free with registration - PR Newswire Europe - AccessMyLibrary.com

Albumin interferon alfa-2b.  -  Feb 1, 2007
Albumin interferon alfa-2b. * Albumin interferon alfa-2b. McHutchison J, Zeuzem S, Benhamou Y, et ai. Interim antiviral and safety data with albumin ... $9.94 - Formulary - Alacra Store

Systemic Adjuvant Therapy for Patients With High-Risk Melanoma  -  Nov 10, 2006
Question: What is the evidence that systemic adjuvant therapy is of benefit in patients with high-risk resected melanoma? In their study, Verma et al ... Archives of Dermatology

Albumin interferon alfa-2b.(Selected literature)(Brief article)  -  Feb 1, 2007
...* Albumin interferon alfa-2b. McHutchison J, Zeuzem S, Benhamou Y, et ai. Interim antiviral and safety data with albumin interferon alfa-2b combined with ... $4.95 - Formulary - ECNext

Chronic hepatitis B treatment  -  May 18, 2008
SCHERING-Plough recently announced that the pegylated interferon alfa-2b drug has been approved by the Malaysian Drug Control Authority for the treatment of ... Malaysia Star

GI Journal Scan Dec 2004  -  Jan 18, 2005
Journal Scan is the clinician's guide to the latest clinical research findings in Gastroenterology, Hepatology, The American Journal of Gastroenterology, ... Medscape

Emerging strategies for pegylated interferon combination therapy  -  Aug 8, 2006
Several advances afford promise for improving the management of hepatitis C virus (HCV) infection. Current therapies primarily target the immune system; ... Nature.com

Combo Tx for melanoma lacks survival advantage.(Clinical Rounds) | …  -  Jul 1, 2005
Combo Tx for melanoma lacks survival advantage.(Clinical Rounds) ... find Skin & Allergy News articles. VIENNA -- Combination therapy with the brain cancer ... Pay-Per-View - Skin & Allergy News - HighBeam Research

Summary and Introduction  -  Mar 1, 2006
Interferon alfa 2b alone or in combination with ribavirin as initial treatment for chronic hepatitis C. N Engl J Med 1998; 339: 1485-1492. ... Medscape

What treatments work?  -  Sep 1, 2008
Melanoma is a type of skin cancer that usually starts as a dark spot or mole on your skin. It is the most serious type of skin cancer and can spread to ... guardian.co.uk

Summary and Introduction  -  Sep 12, 2005
Tong MJ, Blatt LM, McHutchison JG, Co RL, Conrad A. Prediction of response during interferon alfa 2b therapy in chronic hepatitis C patients using viral and ... Medscape

Schering-Plough Presents Positive Results From Phase III Melanoma …  -  Jul 14, 2008
Schering-Plough and the European Organization for the Research and Treatment of Cancer have announced positive results from a randomized Phase III melanoma ... RedOrbit

New paradigms in the management of hepatitis C virus co-infections  -  Jul 31, 2006
Liver disease has emerged as a major contributor to morbidity and mortality in patients with HIV infection. Hepatitis C virus (HCV) infection is a key ... Nature.com

Immunotherapy Used Successfully to Treat Warts  -  May 18, 2005
By Archives of Dermatology, [RxPG] Injection of skin test antigens (preparations used in skin tests for immunity) into warts appears to stimulate the immune ... RxPG NEWS

Type I interferon deemed central to SLE therapy.(Across Specialties)...  -  Aug 1, 2008
Type I interferon deemed central to SLE therapy.(Across Specialties) ... find Skin & Allergy News articles. WAIKOLOA, HAWAII -- Recent developments ... Pay-Per-View - Skin & Allergy News - HighBeam Research

peginterferon alfa-2b Schering Plough clinical data (hepatitis C).  -  Dec 11, 2006
On 27 October 2006 Shering-Plough reported further data from EPIC3, a large multicenter clinical study in chronic HCV patients who failed previous ... Pay-Per-View - R & D Focus Drug News - Factiva, from Dow Jones

Data on PEG-INTRON(R) and REBETOL(R) Combination Therapy in …  -  May 12, 2005
KENILWORTH, NJ, May 12 /PRNewswire-FirstCall/ -- Important new data on PEG-INTRON(R) (peginterferon alfa-2b) and REBETOL(R) (ribavirin, USP) combination ... RedOrbit

Pharmacodynamics and Viral Kinetics during Albinterferon Alfa-2b …  -  Dec 15, 2008
Lynn Rozenberg; 1 Vince G. Bain; 2 John G. McHutchison; 3 Erik Pulkstenis; 4 GM Subramanian; 4 Avidan U. Neumann 1. Abstract: Background: Using mathematical ... Cortlandt Forum

Novartis strengthens infectious disease portfolio by acquiring rights...  -  Jun 6, 2006
Corporate news announcement processed and transmitted by Hugin ASA. The issuer is solely responsible for the content of this announcement. ... Free with registration - Europe Intelligence Wire - AccessMyLibrary.com

Schering-Plough Highlights PEGINTRON(TM) Clinical Data Presentations …  -  Oct 30, 2007
KENILWORTH, NJ, Oct. 30 /PRNewswire-FirstCall/ -- Leading researchers will present 68 data presentations involving Schering-Plough's hepatitis products, ... RedOrbit

Dermatologists Use Immunotherapy to Treat Warts  -  May 12, 2005
Newswise — Injection of skin test antigens (preparations used in skin tests for immunity) into warts appears to stimulate the immune system and successfully ... newswise.com

Valeant Pharmaceuticals Initiates Taribavirin Phase 2b Clinical Study  -  Mar 14, 2007
Valeant Pharmaceuticals (NYSE:VRX) today announced that it has begun enrolling patients in a Phase 2b clinical study for its antiviral compound, taribavirin ... Genetic Engineering News - Genetic Engineering News (press release)

Dermatologists Use Immunotherapy to Treat Warts  -  May 22, 2005
Injection of skin test antigens (preparations used in skin tests for immunity) into warts appears to stimulate the immune system and successfully treat the ... i-newswire.com

The role of cytoreductive nephrectomy for renal cell carcinoma in the...  -  Apr 29, 2008
Cytoreductive nephrectomy (CN) is well-established as an integral part of the treatment of patients with metastatic renal cell carcinoma (RCC). ... Nature.com

Autoimmunity During Interferon Treatment for Melanoma Linked with …  -  Feb 21, 2006
Among patients receiving immunotherapy for melanoma, those who showed evidence of autoimmunity (an immune response against the body's own tissues) survived ... emaxhealth.com

Press Release: FDA Grants Priority Review for Schering-Plough's …  -  Jan 31, 2008
FDA Grants Priority Review for Schering-Plough's Peginterferon Alfa-2b for the Adjuvant Treatment of Patients With Stage III Melanoma. from PR Newswire. Pay-Per-View - PR Newswire - HighBeam Research

Making choices: women, younger patients more likely to select...  -  Oct 1, 2007
However, a one-year course of interferon-alfa-2b is linked to hematologic ... Moreover, results of clinical trials with interferon alfa-2b have been mixed, ... $4.95 - Dermatology Times - ECNext

Combination Therapy for Chronic Hepatitis B: Simultaneous or Sequentia...  -  Sep 19, 2006
Correspondence: Man-Fung Yuen, MD, PhD, Department of Medicine, The University of Hong Kong, Queen Mary Hospital, Pokfulam Road, Hong Kong. ... Nature.com

Abstract and Introduction  -  Jul 7, 2005
Melanoma is the fastest growing solid tumor in men and women, and despite accounting for only 4% of skin cancer cases, it accounts for more than 79% of skin ... Medscape

Quality of life and cost-effectiveness of interferon-alpha in...  -  Nov 4, 2005
A definitive conclusion regarding the value of low-dose extended duration adjuvant interferon-alpha therapy in the treatment of malignant melanoma is only ... Nature.com

Ribavirin (Systemic).  -  Oct 27, 2005
Ribavirin (rye-ba-VYE-rin) is used to treat severe virus pneumonia in infants and young children. It is given by oral inhalation (breathing in the medicine ... Free with registration - USP DI-Volume II, Advice for the... - AccessMyLibrary.com

Press Release: Telenor Resists Alfa's Attempt to Gain Control of …  -  Jun 7, 2005
Telenor Resists Alfa's Attempt to Gain Control of VimpelCom. from PR Newswire Europe. Highbeam Research – FREE Trial. Pay-Per-View - PR Newswire Europe - HighBeam Research

Treatment of Chronic Hepatitis C Virus in African Americans With …  -  May 12, 2006
Previous studies have documented that sustained virologic response (SVR) is significantly reduced in African Americans with chronic HCV genotype 1 following ... Nature.com

Bloomberg Printer-Friendly Page  -  Jul 10, 2008
By Chantal Britt. July 11 (Bloomberg) -- Schering-Plough Corp.'s hepatitis drug helped reduce recurrence of the deadliest form of skin cancer in a ... Bloomberg

Press Release: Celgosivir Combination Therapy Demonstrates Positive …  -  Nov 6, 2006
Celgosivir Combination Therapy Demonstrates Positive Clinical Benefit in Chronic Hepatitis C Non-Responder Patients. from PR Newswire. Pay-Per-View - PR Newswire - HighBeam Research

European Union's CHMP Issues Positive Opinion on PEGINTRON(Tm) …  -  Apr 30, 2007
KENILWORTH, NJ, April 30 /PRNewswire-FirstCall/ -- Schering-Plough Corporation today reported that the Committee for Medicinal Products for Human Use (CHMP) ... RedOrbit

Article: Combination therapy for HCV assessed.(Gastroenterology)( …  -  Jul 1, 2006
Long-term treatment with pegylated interferon alfa-2b in stage III melanoma ... Median RFS was 34.8 months in the pegylated interferon alfa-2b arm vs. ... Pay-Per-View - Internal Medicine News - HighBeam Research

Press Release: Coley Pharmaceutical Group Reports First Quarter …  -  May 11, 2006
Coley Pharmaceutical Group Reports First Quarter Financial Results. from PR Newswire. Highbeam Research – FREE Trial. Pay-Per-View - PR Newswire - HighBeam Research

Lamivudine is still useful against some hepatitis B.(Gastroenterology)...  -  Oct 1, 2006
Lamivudine is still useful against some hepatitis B.(Gastroenterology)(Clinical report) ... find Internal Medicine News articles. SOUTH LAKE TAHOE, CALIF. Pay-Per-View - Internal Medicine News - HighBeam Research

Interferon- after autologous stem cell transplantation in pediatric...  -  Apr 18, 2006
Maintenance therapy with interferon Alfa 2b in Hodgkin disease. Leukemia Lymphoma 1998; 30: 651–656. | PubMed | ChemPort |. Parmar S, Platanias LC. ... Nature.com

Hepatitis C Virus/HIV Coinfection  -  Apr 13, 2005
Data from 4 major trials evaluating the treatment of hepatitis C virus (HCV) in HIV-HCV coinfection make it clear that many HIV-infected individuals can be ... Medscape

Ribavirin and Use of Clotting Factors in Patients With Hemophilia and...  -  Mar 9, 2005
To the Editor: Ribavirin has been used in combination with interferon (IFN) alfa to treat chronic hepatitis C. This combination therapy has been reported to ... Journal of American Medical Association - Journal of American Medical Association...

Long-Term Follow-Up of Previous Hepatitis C Virus Positive …  -  Dec 14, 2005
A randomized 4-arm multicenter study of interferon alfa-2b plus ribavirin in ... Peginterferon alfa-2b plus ribavirin compared with interferon alfa-2b plus ... Nature.com

Intron-A may reduce West Nile complications.(Rx)  -  Jan 1, 2005
WASHINGTON -- Interferon alfa-2b reduced the severity of neurologic symptoms in patients infected with West Nile virus, according to the results of a small ... Pay-Per-View - Internal Medicine News - Factiva, from Dow Jones

STAT3 as a Biomarker of Progression in Atypical Nevi of Patients with...  -  Feb 28, 2008
Correspondence: Dr John M. Kirkwood, Department of Medicine, University of Pittsburgh, Melanoma and Skin Cancer Program, University of Pittsburgh Cancer ... Nature.com

Hepatitis Combination Therapy Okay for Children: Study  -  Nov 15, 2005
...by John C. Martin. Adding the antiviral medication, ribavirin, to interferon as a combination therapy for children with hepatitis C is "effective" and ... Hepatitis Neighborhood

Chronic Hepatitis C in Latinos: Natural History, Treatment Eligibility...  -  Feb 27, 2005
The natural history of chronic hepatitis C and treatment response are different between blacks and Caucasians, but little comparable data is available about ... Nature.com

Competitors by Product Report  -  Mar 29, 2008
Enzon Pharmaceuticals, Inc. (ENZN) Products:. PEG-Intron A (PEG-Interferon Alfa 2B Recombinant Human); Pegasys (Pegylated Interferon Alfa-2a) ... $75.00 - Revere Reports - Revere

Competitors by Product Report  -  Mar 1, 2008
Enzon Pharmaceuticals, Inc. (ENZN) Products:. PEG-Intron A (PEG-Interferon Alfa 2B Recombinant Human); Pegasys (Pegylated Interferon Alfa-2a) ... $75.00 - Revere Reports - Revere

FDA Safety Labeling Changes: Aranesp, Avastin, Intron A  -  Apr 6, 2005
April 6, 2005 — The US Food and Drug Administration (FDA) announced in January revisions to safety labeling to advise healthcare professionals of the ... Medscape

Autoimmunity Suggests Better Response to Interferon for Melanoma  -  Feb 16, 2006
NEW YORK FEB 16, 2006 (Reuters Health) - Autoimmunity during treatment of melanoma with interferon alfa-2b signals longer relapse-free and overall survival, ... Cancerpage.com

Condylomata Acuminata; Pegylated IFN alfa-2b safe and effective for...  -  Apr 26, 2006
2006 APR 26 - (NewsRx.com) -- Pegylated interferon alfa-2b safe and effective for HIV-related condylomata acuminata. "Interferon in a variety of topical, ... Pay-Per-View - Life Science Weekly - Factiva, from Dow Jones

Hepatitis C: reviewing the options.(Letter to the editor)  -  Jul 4, 2006
Tom Wong and Samuel Lee (1) mention some extrahepatic manifestations of infection with hepatitis C virus (HCV), but they do not discuss the urticarias. ... Free with registration - CMAJ: Canadian Medical Association... - AccessMyLibrary.com

Press Release: Milliman Releases MG-ALFA(R) Version 6.6. - PR …  -  Jun 16, 2008
Milliman Releases MG-ALFA(R) Version 6.6. from PR Newswire. Highbeam Research – FREE Trial. Pay-Per-View - PR Newswire - HighBeam Research

Press Release: Idenix Pharmaceuticals, Inc. Announces Results of...  -  Jun 12, 2007
Idenix Pharmaceuticals, Inc. Announces Results of Phase II Trial. from M2 Presswire. Highbeam Research – FREE Trial. Pay-Per-View - M2 Presswire - HighBeam Research

Article: HCV therapy during HIV coinfection.(CLINICAL CAPSULES)(Brief...  -  Jan 15, 2005
HCV therapy during HIV coinfection.(CLINICAL CAPSULES)(Brief Article) ... find Internal Medicine News articles. Pegylated interferon alfa-2b plus ribavirin ... Pay-Per-View - Internal Medicine News - HighBeam Research

FDA Safety Changes: Keppra, Naropin, Rebetol  -  Dec 22, 2006
December 22, 2006 — The US Food and Drug Administration (FDA) has approved safety label revisions to advise of the expected similarity of levetiracetam's ... Medscape

Press Release: Research and Markets: Less than 50% of Chronically …  -  May 16, 2005
Research and Markets: Less than 50% of Chronically Infected Hepatitis C Patients Do Not Benefit from the Current Standard of Care, Pegylated Interferon Plus ... Pay-Per-View - PR Newswire - HighBeam Research

Press Release: Coley Pharmaceutical Group Announces Top-line Data …  -  Mar 21, 2006
Long-term treatment with pegylated interferon alfa-2b in stage III melanoma ... Median RFS was 34.8 months in the pegylated interferon alfa-2b arm vs. ... Pay-Per-View - PR Newswire - HighBeam Research

Press Release: Idenix Reports Interim Analysis of a Phase IIa...  -  Jan 10, 2005
Idenix Reports Interim Analysis of a Phase IIa Clinical Trial of Valopicitabine (NM283) in Combination with Pegylated Interferon in Treatment- Naive ... Pay-Per-View - PR Newswire - HighBeam Research

Press Release: Valopicitabine Combined with Standard of Care Cleared ...  -  Jun 12, 2007
Valopicitabine Combined with Standard of Care Cleared Hepatitis C Virus in 72% of Patients Who Completed 12 Weeks of Treatment in a Phase II Trial. from PR ... Pay-Per-View - PR Newswire - HighBeam Research

A Pilot Study of Extended Duration Peginterferon Alfa-2a for Patients...  -  Feb 6, 2007
A randomized, controlled trial of a 24-month course of interferon alfa 2b in patients with chronic hepatitis B who had hepatitis B virus DNA without ... Nature.com

Treatment of Chronic Hepatitis B Infection  -  Oct 15, 2005
Chronic hepatitis B infection can lead to cirrhosis, hepatic failure, and hepatocellular carcinoma. Current therapies are successful in a minority of ... AAFP News Now

Press Release: MIGENIX receives approval to initiate MX-3253 Phase...  -  Aug 11, 2005
MIGENIX receives approval to initiate MX-3253 Phase IIb combination study in HCV non-responders. from PR Newswire. Highbeam Research – FREE Trial. Pay-Per-View - PR Newswire - HighBeam Research

Peg-Interferon Improves Event-Free Survival Compared With Colchicine ...  -  Apr 25, 2008
...[Presentation title: Colchicine Versus Peg-Interferon Alfa 2b Long Term Therapy: Results of the 4 Year COPILOT Trial. Abstract 3] DG News

Pharmacologic management of chronic hepatitis B.  -  Jul 1, 2007
Pharmacologic management of chronic hepatitis B. * Abstract Chronic hepatitis B is a common disease worldwide with significant morbidity and mortality. ... $9.94 - Formulary - Alacra Store

Treatment for renal cancer: are we beyond the cytokine era?  -  Jan 9, 2006
Cytokines have been the mainstay of treatment for metastatic renal cancer for the past 20 years. Response rates of patients treated with these agents are ... Nature.com

Results of PEG-INTRON(R) and REBETOL(R) Study in Retreating …  -  Oct 27, 2006
BOSTON, Oct. 27 /PRNewswire-FirstCall/ -- Schering-Plough today reported data from EPIC3, a large ongoing clinical study, showing that retreatment with ... RedOrbit

Peg-Interferon Slows Melanoma Recurrence  -  Jul 10, 2008
Interferon alfa-2b, at both high and intermediate doses, has previously been ... The median length of treatment with pegylated interferon alfa-2b was 12 ... MedPage Today

Modified interferon improves melanoma survival  -  Jul 11, 2008
A chemically modified form of interferon alfa-2b improves recurrence-free survival (RFS) in melanoma patients compared with observation alone, ... Pharmacy Europe

Pegylated Interferon/Lamivudine Combo Tested as HBV Therapy  -  Jan 19, 2005
...by John C. Martin. Standard interferon has been used as a form of therapy for hepatitis B (HBV) for more than two decades. 1 Currently, interferon alfa-2b ... Hepatitis Neighborhood

Schering-Plough Addresses Major Milestones and Challenges in …  -  Apr 11, 2007
KENILWORTH, NJ, April 11 /PRNewswire-FirstCall/ -- Schering-Plough Corporation reaffirms its commitment to advancing the science and treatment of chronic ... Free with registration - PR Newswire - AccessMyLibrary.com

Cancer Therapy; Recent studies add new data to cancer therapy research  -  Nov 22, 2005
2005 NOV 22 - (NewsRx.com) -- Investigators in the United States, Netherlands and United Kingdom have published new cancer therapy data. ... Pay-Per-View - Life Science Weekly - Factiva, from Dow Jones

Brand Names/Synonyms:
Interferon alfa-2b is also known by the following brand names and/or synonymsInterferon alpha-2 precursor;Interferon alpha-A;LeIF A; Intron A (Schering Corp)

Drug Category:
Interferon alfa-2b is categorized under the following by the FDA: Antiviral Agents; Immunomodulatory Agents; Antineoplastic Agents; interferons (08:18.20);antineoplastic agents (10:00.00)

Dosage Forms:
LIQUID

Absorption:
Not Available

Interactions:
Not Available



Chemical IUPAC Name:
Not Available





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