Kaletra

This page contains recent news articles, when available, and an overview of Kaletra but does not offer medical advice. You should contact your physician with regard to any health issues or concerns.


Overview:

Kaletra
(when available)

Pharmacology and use:
Ritonavir is a protease inhibitor with activity against Human Immunodeficiency Virus Type 1 (HIV-1). Protease inhibitors block the part of HIV called protease. HIV-1 protease is an enzyme required for the proteolytic cleavage of the viral polyprotein precursors into the individual functional proteins found in infectious HIV-1. Ritonavir binds to the protease active site and inhibits the activity of the enzyme. This inhibition prevents cleavage of the viral polyproteins resulting in the formation of immature non-infectious viral particles. Protease inhibitors are almost always used in combination with at least two other anti-HIV drugs. Indicated in combination with other antiretroviral agents for the treatment of HIV-infection.

Mechanism Of Action:
Ritonavir inhibits the HIV viral proteinase enzyme which prevents cleavage of the gag-pol polyprotein, resulting in noninfectious, immature viral particles.

News Articles on Ritonavir

Claims in drug advertising are attracting new scrutiny | Philadelphia Inquirer ...  -  ‎Dec 14, 2009‎
The FDA wrote to Illinois-based Abbott Laboratories, Kaletra's manufacturer, in July warning about unsubstantiated claims of long-term effectiveness. ... Philadelphia Inquirer

Global Sales of Abbotts Kaletra 2000-2006 ----Aarkstore Enterprise  -  ‎Jan 4, 2010‎
This Database Table is a one-page table of hard-to-find numerical information. The Database Table is derived from a proprietary source and is meant to ... PRMinds (press release)

FDA gets tough on ads for drugs  -  ‎Dec 10, 2009‎
The FDA wrote to Illinois-based Abbott Laboratories, Kaletra's manufacturer, in July warning about unsubstantiated claims of long-term effectiveness. ... Trading Markets (press release)

Does Switching to Norvir-Boosted Reyataz Spare the Heart?  -  ‎Dec 31, 2009‎
Most had been on Kaletra (lopinavir plus ritonavir). Twenty-four weeks into the study, people who switched to Norvir-boosted Reyataz saw significant ... AIDSmeds.com HIV/AIDS Treatment News

Reportlinker Adds The Future of HIV Therapeutics - Market Forecasts to 2015 ...  -  ‎Dec 15, 2009‎
Viread 9.3.4 Isentress 9.3.5 Trizivir 9.3.6 Kaletra 9.3.7 Reyataz 9.3.8 Combivir 9.3.9 Epzicom/Kivexa 9.3.10 Sustiva Franchise 9.4 Competitive Profiling ... IT News Online

Concert: protease inhibitor holds potential to be prescribed un-boosted  -  ‎Nov 10, 2009‎
While newer PIs such as Kaletra (lopinavir; Abbott), Reyataz (atazanavir; Bristol-Myers Squibb) and Prezista (darunavir; Tibotec) have addressed many of ... Trading Markets (press release)

What Risks Are Associated With High-Dose Rosuvastatin?  -  ‎Oct 22, 2009‎
...hypothyroidism, renal impairment, and coadministration with cyclosporine, lopinavir/ritonavir (Kaletra®), fibrates, niacin, or gemfibrozil. ... Medscape

Lower Norvir Boosting Dose Possible  -  ‎Oct 29, 2009‎
Hill and his colleagues also looked at studies with lopinavir (combined with ritonavir in Kaletra), Reyataz (atazanavir), Crixivan (indinavir) and Aptivus ... AIDSmeds.com HIV/AIDS Treatment News

Abbott cuts price of AIDS drug Kaletra by 55 pct in poor countries  -  Apr 11, 2007
CHICAGO (Thomson Financial) - Abbott Laboratories said it has agreed to more than halve the price of a key AIDS treatment Kaletra in more than 40 poor ... Forbes

Thai govt approves generic versions of Kaletra, Plavix  -  Jan 29, 2007
BANGKOK (XFN-ASIA) - The health ministry said it has approved generic versions of the anti-AIDS drug Kaletra and the blockbuster heart drug Plavix. ... Forbes

Abbott, Brazil in AIDS pact: Price of Kaletra drug to be slashed.  -  Jul 6, 2007
Jul. 6--For more than a year the world's pharmaceutical giants have been battling to protect their patents in the face of threats by developing nations to ... Free with registration - Chicago Tribune - AccessMyLibrary.com

Kaletra change OKd  -  May 3, 2005
Abbott Laboratories said it has received U.S. approval to market the HIV drug Kaletra, the most-prescribed drug in its class for the virus that causes AIDS, ... Pay-Per-View - Chicago Tribune - ProQuest Archiver

Abbott's tablet form of Kaletra gains EU marketing authorization  -  Jul 3, 2006
LONDON (AFX) - Abbott Laboratories said it has received marketing authorization from the European Commission for the tablet form of Kaletra drug, ... Forbes

J&J says Prezista matches Kaletra in HIV trial  -  Sep 18, 2007
By Ransdell Pierson. NEW YORK (Reuters) - Johnson & Johnson said on Tuesday its drug Prezista was as effective in a late-stage trial as Abbott Laboratories ... Reuters

Kaletra monotherapy as effective as triple therapy for at least 18...  -  Aug 18, 2006
Following on from the results of the KalMo study, presented on Tuesday at the Sixteenth International AIDS Conference in Toronto, three more studies ... Aidsmap

Brazil and US Maker Reach Deal on AIDS Drug  -  Jul 9, 2005
Under the agreement, Brazil's annual expenses for Kaletra will remain unchanged for the next six years, even though the number of patients that require the ... New York Times

Abbott's Kaletra(R) Tablet Dosed Once-Daily or Twice-Daily …  -  Aug 5, 2008
MEXICO CITY, Aug. 5 /PRNewswire-FirstCall/ -- Initial treatment regimens containing once-daily or twice-daily dosing of Abbott's protease inhibitor ... RedOrbit

Abbott to Cut New Kaletra Price by 30% in Brazil  -  Jul 4, 2007
By Katia Cortes. July 4 (Bloomberg) -- Abbott Laboratories, the third largest US drugmaker, agreed to cut the price of its new AIDS treatment drug Kaletra ... Bloomberg

Abbott faces more litigation over AIDS drug  -  Aug 3, 2008
Corporate documents produced in court showed Abbott executives hoped that the price increase in 2003 would boost sales of Kaletra at the expense of two ... FOXNews

Abbott expands its AIDS program: 45 countries to get drug at lower...  -  Aug 14, 2006
In the United States, Kaletra costs more than $7500 a year per patient. In expanding the program Abbott said it would add countries considered "low income," ... Free with registration - Chicago Tribune - AccessMyLibrary.com

RedHerring.com ~ The Business of Technology  -  Jun 27, 2005
Although Abbott has brought the unit price of Kaletra down from $1.60 to $1.17 since ... One-third of the 2008 budget is earmarked for the purchase of Kaletra. Red Herring

Abbott shareholders vote down proposals: Measures on executive pay, …  -  Apr 29, 2006
The newer tablet form of Kaletra, which is in a class of HIV medicines called ... Abbott is making Kaletra available for $500 per patient per year in nearly ... Free with registration - Chicago Tribune - AccessMyLibrary.com

AIDS patients to protest in front of Abbott Labs  -  Apr 26, 2007
The Thai Government has understood the problem, out of the total five lakh HIV-AIDS people, about 50000 would need second-line medicines like Kaletra, ... Hindu Business Line

Theft, extortion and AIDS  -  Jul 6, 2005
In this case it's Abbott's Kaletra, one of the most potent AIDS drugs. ... Kaletra is the most potent member of a family of drugs called protease inhibitors ... Pay-Per-View - Chicago Tribune - ProQuest Archiver

Abbott faces more litigation over AIDS drug  -  Aug 4, 2008
Corporate documents produced in court showed Abbott executives hoping that the price increase in 2003 would boost sales of Kaletra at the expense of two ... San Francisco Chronicle

AIDS activists target Abbott's Kaletra  -  Mar 26, 2006
AIDS activists have set their sights on Abbott Laboratories aimed at making the newly reconstituted Kaletra available in less developed nations at no profit ... FierceBiotech

Brazil Says Deal on Drug Isn't Assured  -  Jul 16, 2005
Last Friday, the government and Abbott announced an agreement that would freeze the annual amount Brazil pays for Kaletra over the next six years, ... New York Times

Abbott to settle lawsuit over HIV drug pricing  -  Jul 31, 2008
The plaintiffs contended that Abbott increased Norvir's price in hopes of switching patients to a newer medicine, Kaletra, its own combination HIV treatment ... Reuters UK

Abbott to offer new AIDS drug in Thailand  -  Apr 23, 2007
N) to sell a newer form of its AIDS drug Kaletra at a discounted price, ... Abbott announced earlier this month it would cut the price of Kaletra by more ... Reuters

Brazil Near Deal With Abbott for Price Cut on AIDS Drug  -  Oct 5, 2005
A drop in the price of Kaletra, Brazilian officials argued, was essential ... Kaletra is one of 17 medications that doctors use to treat 170000 Brazilians ... New York Times

Once- vs. Twice-Daily Kaletra Tablets: Similar Safety and Potency  -  Feb 5, 2008
By Tim Horn. Once- and twice-daily doses of Kaletra (lopinavir/ritonavir) tablets have similar tolerability and comparable efficacy, according to 48-week ... AIDSmeds.com HIV/AIDS Treatment News

Africa: New-Version Kaletra Victory for MSF  -  Jul 26, 2006
Johannesburg — A new version of the second-line antiretroviral (ARV) drug, Kaletra, began arriving in parts of West and Southern Africa this week, ... AllAfrica.com

Abbott investors don't want vote - Say no to vote on executive pay  -  Apr 28, 2007
The government of Thailand, which has contended the price of Kaletra is too ... In refusing to sell the new version of Kaletra and six other drugs there, ... $2.95 - Chicago Sun-Times - NewsBank

Abbott Receives FDA Approval for New Kaletra(R) (Lopinavir/Ritonavir)...  -  Oct 31, 2005
ABBOTT PARK, Ill., Oct. 31 /PRNewswire-FirstCall/ -- Abbott announced today that it has received US Food and Drug Administration (FDA) approval for a new ... Free with registration - PR Newswire - AccessMyLibrary.com

Abbott Labs Meets Estimates  -  Jan 23, 2008
Quarterly sales of the company's HIV drug Kaletra grew 25% to $371 million, and sales of cholesterol drug TriCor rose 20% to $392 million. ... TheStreet.com - TheStreet.com (subscription)

Abbott Kaletra tablet  -  Jul 4, 2006
North Chicago-based Abbott Laboratories received marketing authorization from the European Commission for a tablet formulation of Kaletra, a more convenient ... Pay-Per-View - Chicago Tribune - ProQuest Archiver

Activists: Abbott's image tarnished; AIDS group says suit is a strong...  -  Jun 19, 2007
Thai officials, however, issued a compulsory license for Kaletra and ... In April Abbott lowered the price of Kaletra to $1000 a year in Thailand and more ... Pay-Per-View - Chicago Tribune - ProQuest Archiver

2 nations unite on AIDS care ; Argentina, Brazil vow to make generic ...  -  Aug 25, 2005
And it argues that without strong profits from Kaletra and other successful ... But Brazilian officials say Kaletra itself eats up a third of the country's ... Pay-Per-View - Chicago Tribune - ProQuest Archiver

Abbott sets Asia nutritionals plant  -  Jan 31, 2008
The advisory panel's OK means Kaletra could be available for sale in Europe in 60 to ... Once the lower-strength dosage of Kaletra officially wins European ... Pay-Per-View - Chicago Tribune - ProQuest Archiver

IAC: HIV Suppressed on Long-Term Boosted-Kaletra Monotherapy  -  Aug 21, 2006
By Ed Susman, Contributing Writer, MedPage Today. TORONTO, Aug. 21 -- A high percentage of HIV patients taking monotherapy lopinavir boosted with ritonavir ... MedPage Today

Brazil Threatens AIDS Patent  -  Jun 26, 2005
Although Abbott has brought the unit price of Kaletra down from $1.60 to $1.17 since ... One-third of the 2008 budget is earmarked for the purchase of Kaletra. Red Herring

Abbott in Thailand  -  May 10, 2007
The company also cut the price of Kaletra to $1000 a year for some 40 other developing countries that are several steps up from the poorest. ... Pay-Per-View - Chicago Tribune - ProQuest Archiver

Kaletra monotherapy studies yield conflicting results  -  Jan 28, 2008
Two studies, both published in the January 30 th edition of AIDS, have reported disparate findings on the 48-week effectiveness of lopinavir/ritonavir ... Aidsmap

Abbott's New Tablet Formulation Of Kaletra(R) (Lopinavir/Ritonavir) …  -  Apr 30, 2006
Abbott announced today that the Committee for Medicinal Products for Human Use (CHMP), the scientific committee of the European Medicines Agency (EMEA), ... Medical News Today - Medical News Today (press release)

Abbott Revenue Jumps 16%  -  Apr 12, 2005
Abbott expects Kaletra, its HIV drug, to be approved for a once-daily dosage ... Kaletra is the No. 1 prescribed protease inhibitor, a class of drugs that ... TheStreet.com - TheStreet.com (subscription)

Africa: Daily HIV/Aids Report  -  Mar 14, 2007
The seven withdrawn drugs include a new version of Kaletra; an antibiotic; a painkiller; and medicines to treat blood clots, arthritis, kidney disease and ... AllAfrica.com

Glaxo HIV drug performs well in study  -  May 16, 2006
Glaxo officials said Lexiva was compared to Kaletra in the clinical study because Kaletra is listed by the US Department of Health and Human Services and ... Bizjournals.com

Norvir/Reyataz Comparable to Kaletra for First-Line Therapy  -  Feb 4, 2008
By Tim Horn. Data from a study comparing Norvir (ritonavir)-boosted Reyataz (atazanavir) to Kaletra (lopinavir/ritonavir) suggest that both drugs have ... AIDSmeds.com HIV/AIDS Treatment News

Thailand Expected to Break Patents on Two Drugs  -  Jan 25, 2007
..."Kaletra is the obvious candidate. It is an essential drug for people with HIV, and as time goes by, more people will need it," he said. ... FOXNews

ABBOTT PRESSURED TO CUT PRICE OF ANTI-AIDS DRUG  -  Aug 19, 2005
An estimated 23400 people in Brazil use Kaletra, making it the drug's biggest ... Kaletra is a protease inhibitor that blocks an enzyme involved in the ... $2.95 - Miami Herald - NewsBank

Lexiva HIV treatment 'comparable' to Kaletra  -  Aug 18, 2006
A new study published by The Lancet found GlaxoSmithKline's Lexiva treatment to have comparable effects as Abbott Laboratories' Kaletra. ... Hays Pharma

Thailand to override more patented drugs: minister  -  May 28, 2007
Aluvia is needed badly in tropical Thailand because it does not require refrigeration like Kaletra, eliminating the need for costly cold storage. ... Reuters

Abbott Laboratories faced with anti-Aids drug dilemma  -  Jul 4, 2005
...powers under global trade rules to break Abbott's patent and make a generic copy of the Kaletra pill to cut the costs of its fight against the disease. ... Independent

… boosted atazanavir comparable to twice-daily Kaletra in treatment...  -  Feb 4, 2008
Atazanavir appeared to be better tolerated than Kaletra, ... Fewer patients on atazanavir (2%) than on Kaletra (8%) initiated lipid-lowering therapy during ... Aidsmap

… group urges Thailand to disallow more generic drugs after Plavix,...  -  Feb 15, 2007
...in January decided to allow imports from India of cheaper generic forms of Plavix, the world's second top-selling medicine, and AIDS drug Kaletra. ... Forbes

New Data Show a Kaletra(R) (Lopinavir/Ritonavir)-Based Regimen …  -  Nov 18, 2005
DUBLIN, Nov. 18 /PRNewswire-FirstCall/ -- The longest clinical study of any HIV treatment -- seven years (360 weeks) -- of Kaletra(R) ... biotech-intelligence.com

IAC: Sustiva vs. Kaletra – ACTG Study Declares a Likely Winner  -  Aug 18, 2006
By Tim Horn, Senior Writer & Editor, AIDSmeds.com. The US Department of Health and Human Services (DHHS) currently recommends either Sustiva® (efavirenz) or ... AIDSmeds.com HIV/AIDS Treatment News

Article: Abbott, Brazil in AIDS pact: Price of Kaletra drug to be...  -  Jul 6, 2007
Abbott, Brazil in AIDS pact: Price of Kaletra drug to be slashed. ... find Chicago Tribune (Chicago, IL) articles. Byline: Bruce Japsen Jul. Pay-Per-View - Chicago Tribune - HighBeam Research

Brazil/Abbott Kaletra price deal "near".(Abbott Laboratories Inc....  -  Oct 10, 2005
Agreement is said to be close between Brazil and Abbott Laboratories to cut the price which the country's HIV/AIDS prevention and treatment program pays for ... Free with registration - Pharma Marketletter - AccessMyLibrary.com

IAC: Kaletra Alone Can Keep Suppressed HIV at Bay  -  Aug 16, 2006
By Michael Smith, Senior Staff Writer, MedPage Today. TORONTO, Aug. 16 -- Simplifying HIV treatment by dropping some of the medications can work for an ... MedPage Today

Abbott Net Changes Little as Costs Offset Sales Gain  -  Oct 17, 2007
Rising sales of drugs including Kaletra for HIV and the migraine medicine ... Kaletra gained 15 percent to $338 million, and the cholesterol drug TriCor ... Bloomberg

US presses Thailand on drug patents  -  May 2, 2007
Thailand in January issued compulsory licences for two drugs - a heart disease medicine and the Aids drug Kaletra produced by US drug maker Abbott ... Aljazeera.net

Religious investors criticize Abbott's decision not to introduce new...  -  Mar 22, 2007
Abbott announced the move earlier this month after Thailand said it was going to break the patent on Abbott's AIDS drug Kaletra because the price was too ... San Diego Union - Tribune - San Diego Union Tribune

… and US Regulatory Filings for New Lower-Strength Kaletra(R) and...  -  Jul 20, 2007
The new tablet formulation will complement the availability of Kaletra oral ... Pediatric dosing of Kaletra is based on body surface area or weight. ... Free with registration - PR Newswire - AccessMyLibrary.com

Thailand turns giant pharma killer  -  May 15, 2007
In exchange, the pharma giant wanted the CL for Kaletra dropped. Thai public health officials, out to capitalize on the frequently debated WTO rule, ... Asia Times Online

Article: Abbott Laboratories lowers price of AIDS drug for Brazil. -...  -  Jul 9, 2005
Brazil had threatened to break Abbott's patent on Kaletra and manufacture it in its ... Article: ANTI-RETROVIRAL DRUG KALETRA TO BE PRODUCED IN ... ... Pay-Per-View - Chicago Tribune - HighBeam Research

FDA Approves Abbott's Kaletra for Pediatric Patients  -  Nov 13, 2007
Abbott has received FDA approval for a new lower-strength tablet formulation of its leading HIV protease inhibitor, Kaletra, which is marketed as Aluvia in ... FDA news - FDA news (subscription)

Article: AIDS issue dominates Abbott Labs' annual meeting. - Chicago ...  -  Apr 27, 2007
Laboratories, antiretroviral protease inhibitor Kaletra (lopinavir/ritonavir). The report ... drugmaker eventually hopes to supply generic Kaletra to ... Pay-Per-View - Chicago Tribune - HighBeam Research

Thai activists call for boycott of US drugmaker over generics row  -  Mar 19, 2007
Rosana Tositrakoon from the Thai Holistic Health Foundation defended the government's approval of generic versions of the anti-AIDS drugs Kaletra and ... Forbes

Thailand widens scope of generic drugs  -  Jan 31, 2007
It cited a similar financial constraint on access to Kaletra, an anti-retroviral made by US-based Abbott Laboratories. Around 120000 of an estimated 500000 ... Christian Science Monitor

Drug Interaction Caution With Crestor and Kaletra  -  Jan 7, 2008
Kaletra (lopinavir/ritonavir) can significantly increase blood levels of Crestor (rosuvastatin)—one of the most effective drugs used to lower high ... AIDSmeds.com HIV/AIDS Treatment News

Firms fail on pledge to deliver life-saving drugs  -  Mar 13, 2006
Another big research-based pharmaceutical company, Abbott, has just had a new version of its drug Kaletra licensed in the US. Instead of six pills a day, ... guardian.co.uk

Africa: Daily HIV/Aids Report  -  Apr 16, 2007
The company on Tuesday said it plans to reduce the cost of Kaletra in Thailand ... The company said it will provide Kaletra in the countries for $1000 per ... AllAfrica.com

Prezista/Norvir Bests Kaletra in Treatment-Experienced Patients  -  Jul 6, 2007
...by Tim Horn. Results from a Phase III clinical trial indicate that Prezista (darunavir) plus Norvir (ritonavir) is more effective than Kaletra ... AIDSmeds.com HIV/AIDS Treatment News

… Agreement With Brazilian Government for Kaletra(R) (Lopinavir/Riton...  -  Jul 12, 2005
The price of Kaletra will be dependent on the number of patients treated. ... Kaletra should not be taken by patients who have had an allergic reaction to ... i-newswire.com

EACS: Once-a-day Kaletra can be risky  -  Oct 29, 2007
An analysis of the ARTEMIS trial in which boosted darunavir (DRV/r – Prezista) was compared to boosted lopinavir (LPV/r – Kaletra) indicates that most of ... Aidsmap

Global dispute over drug patents comes to a head  -  Mar 24, 2007
...giant Abbott says it will not sell seven new drugs in Thailand after the country issued a "compulsory licence" for its anti-HIV drug Kaletra. ... New Scientist

US drug makers win little-seen victory in trade pact  -  Jul 2, 2005
The Brazilian government currently buys Kaletra for about 180000 citizens with AIDS. Abbott charges Brazil $2500 per patient, per year. ... New York Times

… Agreement With Brazilian Government for Kaletra(R) (Lopinavir/Riton...  -  Sep 7, 2005
The price of Kaletra will be dependent on the number of patients treated. ... Kaletra should not be taken by patients who have had an allergic reaction to ... FinanzNachrichten.de

Bloomberg Printer-Friendly Page  -  Nov 9, 2007
Glaxo claims Abbott raised prices on Norvir, a boosting agent for protease inhibitors, without increasing the price of Abbott's medicine Kaletra, ... Bloomberg

Daily HIV/Aids Report  -  Feb 15, 2007
Mongkol last month signed the compulsory license, which allows Thailand to produce a lower-cost version of Kaletra, into law. ... AllAfrica.com

Roche says study shows its HIV drug Invirase as effective as Kaletra  -  Oct 25, 2007
By : Agencies. ZURICH (Thomson Financial) - Roche Holdings AG said a phase IIIb trial indicates that its HIV drug Invirase is as effective as the commonly ... ABCmoney.co.uk

MSF calls for rapid registration of heat-stable Kaletra in low-income...  -  Mar 16, 2006
Medicins Sans Frontieres this week called on Abbott Laboratories to speed up the registration of its heat-stable formulation of the protease inhibitor ... Aidsmap

New AIDS drug, new Abbott rival  -  Oct 30, 2008
Kaletra, like other protease inhibitors, is typically taken with two other drugs ... Patients, these doctors say, like the convenience of taking Kaletra, ... Pay-Per-View - Chicago Tribune - ProQuest Archiver

Lexiva and Kaletra Comparable in Long-Term Study  -  Sep 17, 2007
...by Tim Horn. New data reported at the 47th Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC) in Chicago suggest that Norvir ... AIDSmeds.com HIV/AIDS Treatment News

Kenya bans use of recalled HIV/AIDS drug  -  Aug 10, 2007
..."All patients received Kaletra as a replacement. This drug is not inferior to Viracept," he said. Viracept belongs to a class of AIDS drugs known as ... Reuters

AIDS drugs sales seen topping $10 billion by 2015  -  Apr 12, 2007
Just this week Abbott Laboratories Inc., widely criticized for aggressive pricing of its AIDS medicines, agreed to slash the price of its Kaletra AIDS drug ... Reuters UK

Sanofi-Aventis to sign agreement with Thai govt for cheap access to …  -  May 3, 2007
At the end of January, the Thai government authorised the manufacture of generic versions of Abbott's HIV treatment Kaletra, and Sanofi's Plavix to provide ... Forbes

New AIDS drugs bests Kaletra  -  Jul 25, 2007
SYDNEY, July 25 (UPI) -- In a head-to-head clinical trial, Johnson & Johnson's Prezista (darunavir) outperformed Abbott's Kaletra (lopinavir) in controlling ... United Press International

Abbott seeks FDA approval for new form of Kaletra  -  May 4, 2005
Abbott Laboratories said Tuesday it submitted a new drug application to the Food and Drug Administration for a new, more convenient tablet formulation of ... $2.95 - News Sun - NewsBank

Abbott's sickening plot: E-mail trail shows efforts to price-gouge on...  -  Jan 4, 2007
But the executives expected a Norvir price increase would help Kaletra sales ... Kaletra sales in the United States rose 10 percent over the next two years. ... $2.95 - Chicago Sun-Times - NewsBank

Abbott's New Tablet Formulation of Kaletra'R', Lopinavir/Ritonavir, …  -  Sep 12, 2006
MONTREAL, QUEBEC--(CCNMatthews - Sept. 12, 2006) - Abbott Canada announced today that it has received marketing authorization from Health Canada for the ... marketwire.com

Abbott present results of 7-year Kaletra study.(Brief Article)  -  Nov 28, 2005
The results from a long-term assessment of the HIV treatment Kaletra (lopinavir/ritonavir), manufactured by US health care giant Abbott Laboratories, ... $4.95 - Pharma Marketletter - ECNext

Abbott To Reduce Cost Of Antiretroviral Kaletra In Brazil By About...  -  Jul 9, 2007
Abbott Laboratories has agreed to reduce the cost of its antiretroviral drug Kaletra in Brazil by about 30%, Brazilian Health Minister Jose Gomes Temporao ... Medical News Today - Medical News Today (press release)

Abbott hit after Kaletra reaches Africa | Article from Chicago Sun...  -  Aug 7, 2006
Abbott hit after Kaletra reaches Africa ... find Chicago Sun-Times articles. Doctors Without Borders welcomed the arrival of the new tablet formulation of ... Pay-Per-View - Chicago Sun-Times - HighBeam Research

FDA Reminds Clinicians of Appropriate Dosing for Kaletra Oral Solution  -  Aug 14, 2007
August 14, 2007 — Abbott Laboratories, the manufacturer of Kaletra Oral Solution, has released a worldwide Dear Healthcare Provider letter after a ... Medscape

More Lipoatrophy with Sustiva vs. Kaletra  -  Feb 26, 2007
By Tim Horn. Additional results from a study comparing three HIV drug regimens indicates that Kaletra® (lopinavir/ritonavir) combined with two nucleoside ... AIDSmeds.com HIV/AIDS Treatment News

… , Allow Generic Production of Antiretroviral Kaletra Unless Abbott...  -  Jul 1, 2005
Costa said that the Kaletra patent is of public interest, adding that if the patent is broken, it would be the first time Brazil has broken a patent on any ... Medical News Today - Medical News Today (press release)

Abbott Laboratories first-quarter profit rises 3 percent  -  Apr 19, 2006
Also posting double-digit sales increases were its HIV drug Kaletra and several of ... It rose 33 percent in the United States, where Kaletra, TriCor and ... $2.95 - Associated Press Archive - NewsBank

… Thailand against issuing compulsory license for antiretroviral...  -  Feb 7, 2007
Thailand's Ministry of Public Health last week said that it had broken a patent on Kaletra by issuing a compulsory license and Health Minister Mongkol na ... News-Medical.net

Holding Big Pharma's feet to the fire  -  May 17, 2007
That was followed by a compulsory license issued here for Kaletra, another ARV produced by the US pharma multinational Abbott Laboratories. ... Asia Times Online

Abbott warns on risk of overdose with Kaletra liquid  -  Aug 15, 2007
Abbott, the manufacturer of the protease inhibitor Kaletra, has warned healthcare professionals about the risk of overdosing infants and small children when ... Aidsmap

… with concurrent administration of rifabutin and lopinavir/ritonavir...  -  Oct 26, 2007
A 41-year-old HIV-infected man received lamivudine/zidovudine and nevirapine therapy. He also took isoniazid/rifampicin/pyrazinamide and ethambutol for ... Nature.com

Abbott's decision not to introduce new drugs in Thailand criticised  -  Mar 23, 2007
Abbott announced the move earlier this month after Thailand said it was going to break the patent on Abbott's AIDS drug Kaletra because the price was too ... Malaysia Star

Strategies for Success With Kaletra Monotherapy  -  Oct 25, 2007
By David Evans. Switiching from Kaletra (lopinavir/ritonavir) plus nucleoside reverse transcriptase inhibitors (NRTIs) to Kaletra monotherapy may be a safe ... AIDSmeds.com HIV/AIDS Treatment News

Atazanavir/ritonavir as potent over two years as Kaletra, but has...  -  Mar 15, 2006
Atazanavir (Reyataz) with low dose ritonavir is as effective as Kaletra (lopinavir/ritonavir) at suppressing viral load over two years in ... Aidsmap

Pharmaceuticals: Abbott to cut price of Kaletra for Brazil | Article...  -  Jul 6, 2007
Pharmaceuticals: Abbott to cut price of Kaletra for Brazil ... find Chicago Sun-Times articles. The Brazilian government and Abbott Laboratories have agreed ... Pay-Per-View - Chicago Sun-Times - HighBeam Research

… Lexiva(R) (fosamprenavir Calcium) To Kaletra Presented At IAC 2006...  -  Aug 20, 2006
The publication of the48-week clinical study known as KLEAN (Kaletra vs. Lexiva with Epivir(R) (lamivudine) and Abacavir in ART-Naive patients)was announced ... Medical News Today - Medical News Today (press release)

Brand Names/Synonyms:
Kaletra is also known by the following brand names and/or synonymsAbbott 84538; Kaletra; Norvir; Norvir Sec; Ritonavir; Ritonavir [Usan]

Drug Category:
Kaletra is categorized under the following by the FDA: Anti-HIV Agents; HIV Protease Inhibitors; ATC:J05AE03

Dosage Forms:
CAPSULE (100 mg); SOLUTION (80 mg/mL of ritonavir)

Absorption:
The absolute bioavailability of ritonavir has not been determined.

Interactions:
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Chemical IUPAC Name:
1,3-thiazol-5-ylmethyl [3-hydroxy-5-[3-methyl-2-[methyl-[(2-propan-2-yl-1,3-thiazol-4-yl)methyl]carbamoyl]amino-butanoyl]amino-1,6-diphenyl-hexan-2-yl]aminoformate





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