Kanamycin

This page contains recent news articles, when available, and an overview of Kanamycin but does not offer medical advice. You should contact your physician with regard to any health issues or concerns.


Overview:

Kanamycin
(when available)

Pharmacology and use:
Kanamycin is an aminoglycoside antibiotic. Aminoglycosides work by binding to the bacterial 30S ribosomal subunit, causing misreading of t-RNA, leaving the bacterium unable to synthesize proteins vital to its growth. Aminoglycosides are useful primarily in infections involving aerobic, Gram-negative bacteria, such as Pseudomonas, Acinetobacter, and Enterobacter. In addition, some mycobacteria, including the bacteria that cause tuberculosis, are susceptible to aminoglycosides. Infections caused by Gram-positive bacteria can also be treated with aminoglycosides, but other types of antibiotics are more potent and less damaging to the host. In the past the aminoglycosides have been used in conjunction with penicillin-related antibiotics in streptococcal infections for their synergistic effects, particularly in endocarditis. Aminoglycosides are mostly ineffective against anaerobic bacteria, fungi and viruses. For treatment of infections where one or more of the following are the known or suspected pathogens: E. coli, Proteus species (both indole-positive and indole-negative), E. aerogenes, K.pneumoniae, S.marcescens, Acinetobacter species

Mechanism Of Action:
Aminoglycosides like Kanamycin "irreversibly" bind to specific 30S-subunit proteins and 16S rRNA. Specifically Kanamycin binds to four nucleotides of 16S rRNA and a single amino acid of protein S12. This interferes with decoding site in the vicinity of nucleotide 1400 in 16S rRNA of 30S subunit. This region interacts with the wobble base in the anticodon of tRNA. This leads to interference with the initiation complex, misreading of mRNA so incorrect amino acids are inserted into the polypeptide leading to nonfunctional or toxic peptides and the breakup of polysomes into nonfunctional monosomes.

News Articles on Kanamycin

Florida TB case most extensively drug-resistant yet in US  -  ‎Dec 29, 2009‎
...resistant to isoniazid, rifampin, any fluoroquinolone and at least one second-line injectable drug, including amikacin, kanamycin or capreomycin. ... Pediatric SuperSite

Lab M culture media aids water-supply management  -  ‎Dec 9, 2009‎
Enterococci are confirmed by demonstrating aesculin hydrolysis on Kanamycin Aesculin Azide Agar. For the isolation of Legionella from clinical and ... Laboratory Talk

SESAME STREET CHARACTERS  -  ‎Nov 5, 2009‎
October 21, 2009, 6:25 pm: In the uncontrollably oversolicitous melanerpes, at my baldly, i kanamycin with thieving ancylidae by fortaz of the determinable ... We've Got Heart (blog)

Trouble on the plate  -  ‎Oct 24, 2009‎
Bt brinjal also has an antibiotic resistance marker which induces resistance to the antibiotic kanamycin. This could be a public disaster since... Financial Express

Transgenic aubergines put on ice  -  ‎Oct 20, 2009‎
...time (the time it takes blood to clot) in goats and rabbits, and caused the plants to produce a protein inducing resistance to the antibiotic kanamycin. ... Checkbiotech.org (press release)

FDA releases 2007 monitoring data for antimicrobial resistance in retail meat  -  ‎Oct 20, 2009‎
The prevalence of gentamicin resistance rose from 20.4 percent in 2002 to 34 percent in 2007, and the prevalence of kanamycin resistance rose from 28.9 ... Food Poison Journal

„ Aber der Husten hörte nicht auf … “ – Eine Tuberkulosepatientin berichtet  -  ‎Oct 28, 2009‎
Derzeit werde ich mit Zweitlinien-Medikamenten behandelt: Kanamycin- Injektion en und Medikamente zum Einnehmen (Pyrazinamid und Ethambutol). meist ... Ärzte ohne Grenzen (Pressemitteilung)

Phòng tránh tương tác các thuốc thưá»?ng gặp  -  ‎Nov 3, 2009‎
Dùng trùng các kháng sinh cùng nhóm: Khi bị nhiá»…m khuẩn hô hấp cấp nặng, cho tiêm gentamycin, ngưá»?i bệnh muốn khá»?i nhanh, chắc ăn uống thêm kanamycin. ... Báo Hoà Bình

Anbau von Gentechnik-Auberginen verhindert  -  ‎Oct 21, 2009‎
Zudem produzierten die Pflanzen ein Protein das zur Resistenz des Antibiotikas Kanamycin führt. Auf Basis dieser Daten könne die Sicherheit der Aubergine ... derStandard.at

… thaliana ABC transporter confers kanamycin resistance to transgenic...  -  Aug 21, 2005
Selectable markers of bacterial origin such as the neomycin phosphotransferase type II gene, which can confer kanamycin resistance to transgenic plants, ... Nature.com

Kanamycin (Oral).  -  Oct 27, 2005
Oral kanamycin (kan-a-MYE-sin) belongs to the family of medicines called antibiotics. It is used before surgery affecting the bowel to help prevent ... Free with registration - USP DI-Volume II, Advice for the... - AccessMyLibrary.com

… States Code of Federal Regulations - 21 CFR § 522.1204 Kanamycin …  -  Jul 11, 2006
21 CFR § 522.1204 Kanamycin sulfate injection. (a) Specifications. Each milliliter of kanamycin sulfate injection veterinary contains either 50 or 200 ... Pay-Per-View - United States Code of Federal Regulation... - Loislaw

Eastern Cape is giving XDR-TB drugs  -  Feb 13, 2007
The other drugs being used in the fight against the diseases are: Amikacin, Kanamycin, Ofloxacin, and Dapsone. The department also denied reports of at ... Independent Online

Figure 1 : Protein-folding location can regulate manganese-binding …  -  Oct 23, 2008
...by mass-fingerprinting. f, Profile of sll1785 (top), and PCR products of sll1785 region confirming kanamycin gene-insertion in sll1785 (bottom left). ... Nature.com

Enzyme structural plasticity and the emergence of broad-spectrum …  -  Feb 22, 2008
...(A) Structure of AAC(6')-Ib in complex with kanamycin (Kan). The solvent-accessible surface is shown, coloured as a function of the electrostatic surface ... Nature.com

Chao Zhang, Denise M Kenski, Jennifer L Paulson, Arale Bonshtien, …  -  May 20, 2005
OD 600 of the cultures was measured after 12 h of incubation at 37 °C. The typical concentration used for kanamycin-resistance selection (100 g/ml) is ... Nature.com

… States Code of Federal Regulations - 21 CFR § 862.3520 Kanamycin...  -  Jul 11, 2006
21 C.F.R. § 862.3520 Kanamycin test system. (a) Identification. A kanamycin test system is a device intended to measure kanamycin, an antibiotic drug, ... Pay-Per-View - United States Code of Federal Regulation... - Loislaw

… - 21 CFR § 520.1204 Kanamycin, bismuth subcarbonate, activated …  -  Jul 11, 2006
21 CFR § 520.1204 Kanamycin, bismuth subcarbonate, activated attapulgite . ... (2) Each tablet contains 100 mg kanamycin (as the sulfate), 250 mg bismuth ... Pay-Per-View - United States Code of Federal Regulation... - Loislaw

Getting Smarter About Genetic Modification  -  Sep 6, 2005
A common marker is a bacterial gene complex that imparts resistance to the antibiotic kanamycin. The ostensibly modified plants are grown in soil containing ... Institute for Ethics and Emerging...

… 2006 - 71 FR 43967 Oral Dosage Form New Animal Drugs; Kanamycin, …  -  Aug 3, 2006
...(2) Each tablet contains 100 mg kanamycin (as the sulfate), 250 mg bismuth subcarbonate, and 500 mg activated attapulgite. * * * * * (c) Conditions of use ... Pay-Per-View - Federal Register 2006 - Loislaw

… Streptomycin Antibacterial, systemic Amikacin Gentamicin Kanamycin...  -  Jul 28, 2005
Aminoglycosides (a-mee-noe-GLYE-koe-sides ) are used to treat serious bacterial infections. They work by killing bacteria or preventing their growth. ... Free with registration - USP DI-Volume II, Advice for the... - AccessMyLibrary.com

… Regulations - 21 CFR § 524.1200 Kanamycin ophthalmic and topical …  -  Jul 11, 2006
21 C.F.R. § 524.1200 Kanamycin ophthalmic and topical dosage forms. Copyright © 2009 Loislaw.com, Inc. All Rights Reserved. Pay-Per-View - United States Code of Federal Regulation... - Loislaw

Illinois Administrative Code - 77 Ill. Adm. Code 790.5500 KANAMYCIN …  -  Aug 10, 2005
77 Ill. Adm. Code 790.5500 KANAMYCIN SULFATE (Repealed) Repealed. (Source: Repealed at 17 Ill. Reg. 15916, effective September 20, 1993) ... Pay-Per-View - Illinois Administrative Code - Loislaw

She looks like a man She's black People are uninformed bigots Women …  -  May 16, 2008
Kanamycin is a broad-spectrum antibiotic. It is however not effective in treating anaerobic ... Kanamycin is effective in treating infections of the lungs, ... Health24.com

Graduate School of Biological Sciences, Nara Institute of Science and...  -  Sep 28, 2005
...(A) Gene targeting fragment encoding kanamycin resistance with short homology ... All mutants contain a kanamycin resistance cassette in place of the gene ... Nature.com

From magic bullets back to the Magic Mountain: the rise of extensively...  -  Mar 1, 2007
...at least rifampin and isoniazid plus resistance to the fluoroquinolones and to at least one of the injectable drugs capreomycin, kanamycin and amikacin. ... Nature.com

日年增六ã€?七å??å??超級抗藥性çµ?核病患  -  Dec 26, 2006
...抗�藥具有抗藥性的話,WHO就將此分類為「多�抗藥性�核��,如果��那黴 素(kanamycin)等第二度用藥以後的抗�藥也具抗藥性的話,此為「超級抗藥性�核��。 ... epochtimes.com

Global distribution of Panton-Valentine leukocidin--positive methicill...  -  Apr 1, 2007
One ST8 isolate was resistant to penicillin, oxacillin, kanamycin, erythromycin ... The aph3'-III gene, which encodes high-level resistance to kanamycin and ... Free with registration - Emerging Infectious Diseases - AccessMyLibrary.com

Figure 1 : eSGA: : E. coli: synthetic genetic array analysis : Nature...  -  Aug 1, 2008
Simultaneously, the recipient F - mutant array strains marked with kan (kanamycin-resistance gene; red box) are pinned onto LB-kanamycin (Kan) plates. ... Nature.com

濫用抗生素å?¯å°Žè‡´è—¥ç‰©æ€§è€³è?¾è?½è¦ºéšœç¤™  -  Mar 7, 2006
...抗生素的濫用或長期使用會產生耳毒性的藥物,最有å??的應該è¦?算是氨基é…?醣 é«”(Aminoglycoside)類的廣效性殺è?ŒæŠ—生素如é?ˆé»´ç´ (streptomycin)ã€?康黴素(kanamycin)ã€?æ–° ... epochtimes.com

Suicide; Data from University of Malaga provide new insights into...  -  Jan 1, 2007
The single mutant strain, carrying now an antibiotic resistance marker other than kanamycin, can be used to introduce a second mutation using the original ... Pay-Per-View - Pharma Business Week - Factiva, from Dow Jones

Gezielter Einbau von Genen mittels Gene Targeting  -  Oct 1, 2008
Ein zweiter Teil der Pflanzen wird auf einem Medium ohne Kanamycin ausgesät. ... Die Pflanzen, in denen das Kanamycin-Resistenzgen erfolgreich restauriert ... bioSicherheit

Global distribution of Panton-Valentine leukocidin--positive methicill...  -  Apr 1, 2007
One ST8 isolate was resistant to penicillin, oxacillin, kanamycin, erythromycin ... The aph3'-III gene, which encodes high-level resistance to kanamycin and ... $4.95 - Emerging Infectious Diseases - ECNext

In vivo and in vitro protein solubility assays using split GFP  -  Sep 21, 2006
Plate 1 ml on 130-mm diameter nitrocellulose membranes on selective LB-agar Bauer plates containing 35 g/ml kanamycin and 75 g/ml spectinomycin. ... Nature.com

Health considerations regarding horizontal transfer of microbial …  -  Dec 14, 2005
Kharazmi et al [23] observed the transfer of nptII kanamycin resistance marker gene from transgenic potatoes to Bacillus subtilis with defective nptII by ... Free with registration - Journal of Biomedicine and Biotechnology - AccessMyLibrary.com

Enzyme and competent cell quality ensure cloning integrity: PCR...  -  Mar 1, 2005
XL10-Gold cells yielded 27-fold more kanamycin resistant transformants than DH5 ... The entire transformation was spread onto LB agar plates with kanamycin. ... Free with registration - Bioscience Technology - AccessMyLibrary.com

FACTBOX: Tuberculosis around the world  -  Jul 3, 2008
...kanamycin, ofloxacin, ethionamide, Paser, cycloserine and pirazinamide. If the patient does not react to kanamycin, capreomycin replaces it. Reuters

Agarwal et al., High-Level Aminoglycoside Resistance and Beta- …  -  Aug 11, 2008
High-level resistance (HLR) to gentamicin, kanamycin, and streptomycin was ... Frequent occurrence of HLR to kanamycin makes amikacin a poor choice for ... �康・栄養ニュース

Mycobacterium tuberculosis drug resistance, Abkhazia.(Letters)(Letter...  -  Mar 1, 2005
Resistance to kanamycin and ethionamide was 14.3% and 12.8%, respectively, while resistance to ofloxacin was low (1.5%). Fluoroquinolones have not been ... $4.95 - Emerging Infectious Diseases - ECNext

Extensively drug-resistant Mycobacterium tuberculosis, India.(LETTERS)...  -  Sep 1, 2007
Resistance to ofloxacin, kanamycin, and ethionamide was determined by a cut-off of MIC [greater than or equal to] 8 [micro]g/mL, [greater than or equal to] ... $4.95 - Emerging Infectious Diseases - ECNext

Antimicrobial Resistance; Cross-resistance to antibiotics in M. …  -  Oct 11, 2005
According to recent research from the United States, "Capreomycin, kanamycin, amikacin, and viomycin are drugs that are used to treat multidrug-resistant ... Pay-Per-View - Life Science Weekly - Factiva, from Dow Jones

Monsanto Co. v. Bayer Bioscience NV, No. 2007-1109 (Fed. Cir. 01/25/ …  -  Jan 25, 2008
This plant gene should express the insecticide and kanamycin resistance from the same promoter. . . . [27], Bayer's application, as amended following an ... $2.95 - U.S. Court of Appeals, Federal Circuit - VersusLaw

Antibiotic Resistance Genes: A Threat?  -  Dec 12, 2006
Resistance genes for the antibiotics kanamycin and ampicillin, the most commonly used marker genes ... Kanamycin is now rarely prescribed in human medicine. ... GMO Compass

Box 1 : Detection of protein-protein interactions using a simple...  -  Aug 30, 2007
The pREP4 plasmid carries kanamycin resistance. The trimethoprim assures conservation of both pQE-derived vectors on selective medium (Step 3A(vi)), ... Nature.com

Antimicrobial Resistance; Cross-resistance to antibiotics in M. …  -  Oct 16, 2005
According to recent research from the United States, "Capreomycin, kanamycin, amikacin, and viomycin are drugs that are used to treat multidrug-resistant ... Pay-Per-View - Medical Letter on the CDC & FDA - Factiva, from Dow Jones

Molecular Systems Biology  -  Oct 16, 2007
They demonstrated using the indicator hydroxyphenyl fluorescein that norfloxacin, ampicillin and kanamycin, but not five other bacteriostatic antibiotics, ... Nature.com

Unexpected occurrence of plasmid-mediated quinolone resistance …  -  Feb 1, 2008
A. media 42 was also resistant to several aminoglycosides (kanamycin, tobramycin), chloramphenicol, and tetracycline, whereas A. punctata 37 was fully ... Free with registration - Emerging Infectious Diseases - AccessMyLibrary.com

Agrobacterium-mediated transformation of Arabidopsis thaliana using...  -  Jun 29, 2006
In this experiment, we selected primary transformants using kanamycin (+ ... For kanamycin (+ carbenicillin) selection, non-transformed seedlings can ... Nature.com

Figure 2 : Silencing of mammalian genes by tetracycline-inducible...  -  Dec 13, 2007
The expression of kanamycin resistance gene is controlled by a EM-7 promoter (black); simian virus 40 (SV40) promoter (dark blue) controls the expression of ... Nature.com

BAC TransgeneOmics: a high-throughput method for exploration of …  -  Apr 6, 2008
...(a) In the N-terminal cassette, the neomycin-kanamycin resistance gene (neo) is placed inside an artificial intron flanked by loxP sites. ... Nature.com

Harnessing homologous recombination in vitro to generate recombinant ...  -  Feb 11, 2007
Plasmid DNAs from 20 independent kanamycin-resistant colonies (lanes 1–20) and vector control (lane "v") were digested with AfeI. ... Nature.com

W. Steven Pray, PhD, DPh; Joshua J. Pray, PharmD candidate  -  Nov 7, 2005
Aminoglycoside antibiotics (eg, kanamycin, neomycin, amikacin, streptomycin, gentamicin) exhibit cochleotoxicity but also affect the stria vascularis, ... Medscape

Methicillin-resistant Staphylococcus aureus in pigs with exudative …  -  Sep 1, 2007
...([dagger]) T, tetracycline; K, kanamycin; G, gentamicin; Ty, tylosin; L, lincomycin; E, erythromycin; all isolates were also resistant to ampicillin. ... Free with registration - Emerging Infectious Diseases - AccessMyLibrary.com

Federal Register 2007 - 72 FR 62858 Lederle Laboratories et al.; …  -  Nov 7, 2007
USP, 500 mg/2 mL -------------------------------------------------------------- ---------------- ANDA 63-025 Kanamycin Sulfate Injection Do. ... Pay-Per-View - Federal Register 2007 - Loislaw

Antimicrobial-drug susceptibility of human and animal Salmonella …  -  Dec 1, 2005
S. Typhimurium R-type AKSSuT (with resistance to kanamycin) has also recently emerged in the United States (4). Several studies have documented adverse ... $4.95 - Emerging Infectious Diseases - ECNext

Figure - Nature Structural & Molecular Biology  -  Mar 20, 2005
...(a) Map of the NHEJ reporter plasmid pMSG288, which contains a mycobacterial origin of replication (OriM), a kanamycin-resistance gene (kan) and a lacZ gene ... Nature.com

Methicillin-resistant Staphylococcus aureus in pigs with exudative …  -  Sep 1, 2007
...([dagger]) T, tetracycline; K, kanamycin; G, gentamicin; Ty, tylosin; L, lincomycin; E, erythromycin; all isolates were also resistant to ampicillin. ... $4.95 - Emerging Infectious Diseases - ECNext

Figure - Nature Cell Biology  -  Dec 25, 2005
Surviving seedlings from +/gcs1 compl pollen were observed in kanamycin- and gentamicin-containing media (k). (l) Dead wild-type (black bars) and surviving ... Nature.com

Press Releases - Nature Biotechnology  -  Aug 14, 2005
Overexpression of this gene causes resistance to the common antibiotic kanamycin in tobacco plants. Belonging to a group of proteins that specialise in ... Nature.com

Ari Robicsek, Jacob Strahilevitz, George A Jacoby, Mark Macielag, …  -  Dec 20, 2005
Examples of acetylation rate comparisons for (a) kanamycin and ciprofloxacin and ... Michaelis-Menten plots for (c) kanamycin and (d) ciprofloxacin are shown. Nature.com

DRDO develops transgenic tomato  -  Jan 7, 2008
In vitro selection against selectable marker Kanamycin and PCR analysis of regenerated tomato plantlets for promoter (CaMV), Kanamycin (npt-II) and Osmotin ... Financial Express

Notice to Readers: Revised Definition of Extensively Drug-Resistant …  -  Dec 20, 2006
...and rifampin plus resistant to any fluoroquinolone and at least one of three injectable second-line drugs (ie, amikacin, kanamycin, or capreomycin). ... Journal of American Medical Association - Journal of American Medical Association...

Free-living Canada Geese and antimicrobial resistance.(DISPATCHES)  -  Jun 1, 2005
...(19) Tetracycline 0 Sulfamethoxazole 0 Gentamicin 0 Kanamycin 0 Streptomycin 0 Nalidixic acid 0 Resistance to [greater than or equal to] 3 antimicrobial ... $4.95 - Emerging Infectious Diseases - ECNext

Plasmid profile of antibiotic resistant Escherichia coli isolated...  -  Jul 1, 2006
Most of the isolated strains shared resistance to four antibiotics, namely kanamycin, nalidixic acid, streptomycin, and tetracycline and therefore exhibited ... Free with registration - Journal of the Alabama Academy of... - AccessMyLibrary.com

Article: Antibiotics could save nerves.(Biomedicine)(Brief Article) -...  -  Jan 15, 2005
...(FDA) for the use of the kanamycin marker gene in genetically ... number of ... the plant-based ALS marker gene as well as the kanamycin marker gene. ... Pay-Per-View - Science News - HighBeam Research

Dissemination of clonally related Escherichia coli strains expressing...  -  Feb 1, 2008
OXA-1] and aacA4, which confers reduced susceptibility to amikacin and kanamycin. Location and Transferability of [bla.sub.CTX-M-15] The [bla.sub. ... Free with registration - Emerging Infectious Diseases - AccessMyLibrary.com

Vectors for Gene Knockout.(RNA RESEARCH PRODUCTS)  -  Jan 1, 2006
The vector pACD4K-C-1oxP is a linearized E. coli expression vector containing loxP sites to facilitate the removal of the kanamycin marker. ... Free with registration - Bioscience Technology - AccessMyLibrary.com

pVir and bloody diarrhea in Campylobacter jejuni enteritis.(RESEARCH)  -  Jun 1, 2005
...also resistant to nalidixic acid, 2 isolates were also resistant to kanamycin, and 1 isolate was also resistant to both nalidixic acid and kanamycin. ... $4.95 - Emerging Infectious Diseases - ECNext

Skystar Receives Approval for 36 New Veterinary Medicines.  -  Jun 11, 2007
Kanamycin Sulfate Injection is a Western drug that is designed for treatment ... Kanamycin Sulfate Injection is estimated to generate annual revenue of RMB ... Free with registration - PR Newswire - AccessMyLibrary.com

Antibiotic susceptibility of potentially probiotic vaginal lactobacill...  -  Jan 1, 2006
...at concentrations above 10 [micro]g/mL of chloramphenicol, aztreonam, norfloxacin, ciprofloxacin, ceftazidime, ceftriaxone, streptomycin and kanamycin. ... Free with registration - Infectious Diseases in Obstetrics and... - AccessMyLibrary.com

EFSA panel reconfirms opinion on nptII plant gene safety  -  Apr 16, 2007
It said that both kanamycin and neomycin were rarely used because of their side-effects. Although EFSA agrees with EMEA on its evaluation of the use of ... FoodNavigator

Drug-resistant TB on the rise It accounts for at least 5% of all new...  -  Feb 27, 2008
...is resistant to both of those antibiotics and to fluoroquinolones and any of the injectable antibiotics, such as kanamycin or capreomycin. ... San Francisco Chronicle

New plant gene could help allay concerns over GM crops  -  Aug 24, 2005
Overexpression of this gene causes resistance to the common antibiotic kanamycin in tobacco plants. Belonging to a group of proteins that specialise in ... Medical News Today - Medical News Today (press release)

Targeted Disruption Using Group II Introns  -  Jul 1, 2005
To complement the current kanamycin-based TargeTron system (TA0100), Sigma plans to release a series of TargeTron pACD4 vectors that do not insert ... Genetic Engineering News - Genetic Engineering News (press release)

Haplosporidium nelsoni (MSX) rDNA detected in oysters from the Gulf...  -  Apr 1, 2007
1] kanamycin (MP Biomedicals) and 100 [micro]g X-gal and grown overnight at ... 1] kanamycin. Plasmid DNA was isolated with the UltraClean Standard Mini ... Free with registration - Journal of Shellfish Research - AccessMyLibrary.com

Skystar Receives Approval For 36 New Veterinary Medicines  -  Jun 12, 2007
Kanamycin Sulfate Injection is a Western drug that is designed for treatment ... Kanamycin Sulfate Injection is estimated to generate annual revenue of RMB ... Medical News Today - Medical News Today (press release)

From Enemies to Friends  -  Jan 6, 2005
First they engineered both bacteriophages, adding a gene that provides resistance to a different antibiotic (kanamycin for IKe and chloramphenicol for f1). ... corante.com

New plant gene could help allay concerns over GM crops  -  Aug 28, 2005
Overexpression of this gene causes resistance to the common antibiotic kanamycin in tobacco plants. Belonging to a group of proteins that specialise in ... i-newswire.com

Notice to Readers: Revised Definition of Extensively Drug-Resistant …  -  Nov 3, 2006
...and rifampin plus resistant to any fluoroquinolone and at least one of three injectable second-line drugs (ie, amikacin, kanamycin, or capreomycin). ... Pay-Per-View - Morbidity and Mortality Weekly Report - Factiva, from Dow Jones

Louisiana Revised Statutes - 46:2263. Definitions  -  Aug 18, 2005
...(vi) Ototoxic medications, including but not limited to the aminoglycosides used for more than five days, such as gentamicin, tobramycin, kanamycin, ... Pay-Per-View - Louisiana Revised Statutes - Loislaw

University of Wisconsin-Madison; Availability of Environmental …  -  Aug 12, 2005
Strain WPP40 contains an insertion of a kanamycin resistance gene (aph ) cassette ... The kanamycin resistance gene cassette contains aph , which encodes ... Pay-Per-View - Federal Register - Factiva, from Dow Jones

DNA Research; Charge transfer bands' effect on the photo-induced DNA ...  -  Apr 25, 2005
A 50 mcM solution of 1 in presence of 100 mcM phen and kanamycin-A cleaves similar to99% and similar to60% SC DNA to its nicked circular form, respectively, ... Pay-Per-View - Health & Medicine Week - Factiva, from Dow Jones

Agriculture; New plant gene could help allay concerns over GM crops  -  Sep 16, 2005
Overexpression of this gene causes resistance to the common antibiotic kanamycin in tobacco plants. Belonging to a group of proteins that specialize in ... Pay-Per-View - Genomics & Genetics Weekly - Factiva, from Dow Jones

Federal Register 2006 - 71 FR 1506 University of Wisconsin-Madison; …  -  Jan 10, 2006
Strain WPP40 contains an insertion of a kanamycin resistance gene (aph) cassette into ... The kanamycin resistance gene cassette contains aph, which encodes ... Pay-Per-View - Federal Register 2006 - Loislaw

Federal Register 2006 - 71 FR 29606 Availability of an Environmental ...  -  May 23, 2006
...bahiagrass plants that are genetically engineered to express resistance to the herbicide glufosinate and resistance to the antibiotic kanamycin. ... Pay-Per-View - Federal Register 2006 - Loislaw

Press Release: Skystar Receives Approval for 36 New Veterinary …  -  Jun 11, 2007
Kanamycin Sulfate Injection is a Western drug that is designed for treatment ... Kanamycin Sulfate Injection is estimated to generate annual revenue of RMB ... Pay-Per-View - PR Newswire - HighBeam Research

Agriculture; New plant gene could help allay concerns over GM crops  -  Sep 13, 2005
Overexpression of this gene causes resistance to the common antibiotic kanamycin in tobacco plants. Belonging to a group of proteins that specialize in ... Pay-Per-View - Life Science Weekly - Factiva, from Dow Jones

Agriculture; New plant gene could help allay concerns over GM crops  -  Sep 12, 2005
Overexpression of this gene causes resistance to the common antibiotic kanamycin in tobacco plants. Belonging to a group of proteins that specialize in ... Pay-Per-View - Health & Medicine Week - Factiva, from Dow Jones

Federal Register 2006 - 71 FR 11372 Availability of Environmental …  -  Mar 7, 2006
...bahiagrass plants that are genetically engineered to express resistance to the herbicide glufosinate and resistance to the antibiotic kanamycin. ... Pay-Per-View - Federal Register 2006 - Loislaw

Plasmid profile of antibiotic resistant Escherichia coli isolated...  -  Jul 1, 2006
Most of the isolated strains shared resistance to four antibiotics, namely kanamycin, nalidixic acid, streptomycin, and tetracycline and therefore exhibited ... $4.95 - Journal of the Alabama Academy of... - ECNext

Construction of nano-quantity, full-length and normalized cDNA...  -  Jul 1, 2005
After electroporation the bacteria were incubated and plated at different amounts on L-broth kanamycin agar plates for library titer and total colony ... $9.94 - Bioscience Technology - Alacra Store

Simultaneous insertion of 2, 3, or 4 DNA fragments into a single...  -  Aug 1, 2006
Transformants were selected on LB kanamycin plates or on LB kanamycin + X-Gal plates. LR reactions were performed using LR Clonase II Plus. ... $9.94 - Bioscience Technology - Alacra Store

Vibrio cholerae SXT element, Laos.(Letters)(Letter to the Editor)  -  Feb 1, 2005
R391 contains an intact rumAB operon and a transposon-associated kanamycin resistance gene located [approximately equal to] 3.5 kbp from the rumAB operon ... $4.95 - Emerging Infectious Diseases - ECNext

Sigma-Aldrich Introduces New Vectors to Increase the Flexibility of...  -  Oct 17, 2005
The TargeTron Vector pACD4K-C-loxP is a linerized E. coli expression vector containing loxP sites to facilitate the removal of the kanamycin marker. ... $4.95 - PR Newswire - ECNext

New Jersey Administrative Code - 10:58A-4.3 HCPCS procedure codes …  -  Aug 16, 2005
...itraconazole, 50 mg 36.97 (Sporanox) J1840 Injection, kanamycin sulfate, (Kantrex), 3.36 up to 500 mg J1850 Injection, kanamycin sulfate, (Kantrex), ... Pay-Per-View - New Jersey Administrative Code - Loislaw

Vancomycin-resistant Enterococcus faecium clone in swine, Europe.( …  -  Dec 1, 2005
Two Spanish isolates were also highly resistant to streptomycin and kanamycin [aph(3')-IIIa] (Table). All VREF isolates tested carried a Tn1546 type D, ... $4.95 - Emerging Infectious Diseases - ECNext

Tuberculosis in South Africa - A Global System in Crisis - Health -...  -  Mar 20, 2007
...along with two other drugs: a member of the fluoroquinolone class and at least one of three others (capreomycin, kanamycin and amikacin). ... New York Times

Mycobacterium lentiflavum infection in immunocompetent patient.( …  -  Jan 1, 2005
...ethambutol, isoniazid, streptomycin, rifabutin, cycloserine, and terizidon and resistance to rifampin, amikacin, kanamycin, pyrazinamide, and ofloxacin. ... $4.95 - Emerging Infectious Diseases - ECNext

New UN Plan Commits $2.15 Billion to Fight Drug-Resistant Tuberculosis  -  Jun 22, 2007
...to any of the fluoroquinolone class and to at least one of three second-line drugs (amikacin, capreomycin and kanamycin) that are given by injection. ... New York Times

Templatecache ist für diese Session deaktiviert!  -  Apr 17, 2008
Die Kartoffel enthält als gentechnischen Marker ein Gen, das eine Resistenz gegenüber dem Antibiotikum Kanamycin vermittelt. Daran entzündet sich der Streit ... fdp-fraktion.de

Doctors Warn of Powerful and Resistant Tuberculosis Strain  -  Aug 18, 2006
...bacteria resistant to all first- and second-line drugs, including isoniazid, rifampin, ethambutol, streptomycin, kanamycin and ciprofloxacin. ... New York Times

FACTBOX-Tuberculosis and its variants  -  Nov 7, 2007
...resists antibiotics in a class called fluoroquinolones, and at least one of three injectable second-line drugs -- capreomycin, kanamycin, and amikacin. ... Reuters

Nehmen Bakterien Pflanzengene auf?  -  Mar 21, 2006
Diese enthielten nämlich das vollständige Kanamycin-Resistenz-Gen als Markergen . Weil in Pflanze und Bakterium gleiche DNA-Sequenzen vorlagen, ... bioSicherheit

Flavr Savr Tomate Vorteile und Nachteile  -  May 31, 2007
Kanamycin könnte dann nicht mehr als Antibiotikum zur Darmsterilisierung eingesetzt werden. Zu der Thematik bleibt anzumerken, dass eine solche Aufnahme ... Onmeda

Moderne Pflanzenzüchtung - die Amylopektin-Kartoffel  -  Sep 27, 2007
Kürzlich wurde diesbezüglich über den Einsatz des Kanamycin -Resistenzgens nptII als Markergen diskutiert. Die europäische Arzneimittelbehörde (EMEA) betont ... Laborpraxis

Der Chemiekonzern BASF darf seine gentechnisch veränderten …  -  Mar 16, 2007
Doch nun hat die Kommission entschieden, erst noch eine Stellungnahme über die Risiken der Kanamycin-Resistenz bei der Europäischen Arzneimittelbehörde Emea ... taz.de

BASF gene-altered potato is dividing EU  -  Nov 7, 2008
...that reports to the European Commission on food safety issues, said that antibiotics affected by the marker gene - kanamycin and neomycin - had none, ... New York Times

TB Tests Show Promise, but Flaws Limit Progress  -  Jul 24, 2007
...antibiotic class of second-line drugs and to at least one of three injectable second-line drugs like amikacin, capreomycin and kanamycin. New York Times

WHO says drug-resistant TB infects 500,000  -  Jul 3, 2007
...resists antibiotics in a class called fluoroquinolones, and at least one of three injectable second-line drugs -- capreomycin, kanamycin, and amikacin. ... Reuters

Brand Names/Synonyms:
Kanamycin is also known by the following brand names and/or synonymsAminodeoxykanamycin; Bekanamycin; KAN; Kanamycin; Kanamycin A; Kanamycin B; Kanamycin Base; Kanamycin Sulfate; Kantrex; Kenamycin A; Klebcil; NK 1006; NK-1006; Nebramycin Factor 5

Drug Category:
Kanamycin is categorized under the following by the FDA: Anti-bacterial Agents; ATC:A07AA08; ATC:J01GB04; ATC:S01AA24

Dosage Forms:
Not Available

Absorption:
Not Available

Interactions:
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Chemical IUPAC Name:
2-(aminomethyl)-6-[4,6-diamino-3-[4-amino-3,5-dihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl]oxy-2-hydroxy-cyclohexoxy]-tetrahydropyran-3,4,5-triol





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