Ketoconazole

This page contains recent news articles, when available, and an overview of Ketoconazole but does not offer medical advice. You should contact your physician with regard to any health issues or concerns.


Overview:

Ketoconazole
(when available)

Pharmacology and use:
Ketoconazole, like clotrimazole, fluconazole, itraconazole, and miconazole, is an imidazole antifungal agent. For the treatment of the following systemic fungal infections: candidiasis, chronic mucocutaneous candidiasis, oral thrush, candiduria, blastomycosis, coccidioidomycosis, histoplasmosis, chromomycosis, and paracoccidioidomycosis

Mechanism Of Action:
Ketoconazole interacts with 14-α demethylase, a cytochrome P-450 enzyme necessary for the conversion of lanosterol to ergosterol. This results in inhibition of ergosterol synthesis and increased fungal cellular permeability. Other mechanisms may involve the inhibition of endogenous respiration, interaction with membrane phospholipids, inhibition of yeast transformation to mycelial forms, inhibition of purine uptake, and impairment of triglyceride and/or phospholipid biosynthesis. Ketoconazole can also inhibit the synthesis of thromboxane and sterols such as aldosterone, cortisol, and testosterone.

News Articles on Ketoconazole

Dr Scurr: I've got an itchy scalp - how can I cure it?  -  ‎Dec 14, 2009‎
...(as an antiseptic), with a yeast infection like this what you need is an antifungal shampoo, ideally one containing ketoconazole (trade name Nizoral). ... Daily Mail

• Pharmacological class: Kinase inhibitor  -  ‎Dec 12, 2009‎
Concomitant strong CYP3A4 inhibitors (eg, ketoconazole, ritonavir, clarithromycin): avoid; if warranted, reduce dose of pazopanib to 400mg; ... American Journal of Hemotology and Oncology

Zolpidem: Drug Whys  -  ‎Dec 16, 2009‎
Both ketoconazole antibiotics and rifampin have demonstrated increased plasma levels of zolpidem suggesting a need for downward dose adjustment of the ... EMS1.com

幼兒掉髮起膿皰 竟是頭癬作怪  -  ‎Dec 24, 2009‎
...å?ˆä½µä½¿ç”¨æŠ—é»´è?Œé…?æ–¹(ketoconazole, selenium sulfide)的洗髮精,也å?¯ç¸®çŸ­é ­ç™¬æ²»ç™‚療程。在é ?防方é?¢ï¼Œå®¶ä¸­é¤Šçš„貓ã€?狗患皮膚癬è?Œç—…後,也能傳染給人,致æˆ?體癬或頭癬, ... yam天空新聞

Activity of dutasteride plus ketoconazole in castration-refractory prostate ...  -  ‎Nov 4, 2009‎
Ketoconazole is a commonly used secondary hormonal therapy in castration-refractory prostate cancer (CRPC), but disease progression inevitably occurs. ... UroToday

Research reports from University of Sydney, Faculty of Pharmacy provide new ...  -  ‎Nov 9, 2009‎
...(i) The CYP3A4 and CYP1A2 inhibitors ketoconazole and fluvoxamine inhibited CLZ oxidation to varying extents in individual microsomal fractions. ... Behavioral Health Central (blog)

Gilead Sciences Announces Plans for Phase IV Clinical Trial Evaluating First ...  -  ‎Nov 2, 2009‎
No clinically relevant interactions of Letairis with warfarin, sildenafil, tadalafil, omeprazole (CYP2C19 inhibitor), ketoconazole (strong CYP3A-inhibitor), ... WELT ONLINE

Generic Name: Omeprazole Sodium Bicarbonate Capsules, Zegerid  -  ‎Nov 11, 2009‎
If you also take an imidazole antifungal (eg, ketoconazole), take it at least 2 hours before taking Omeprazole/Sodium Bicarbonate. ... Pattaya Daily News

New Study Results Analyzed the Use of KAPIDEX(TM) (dexlansoprazole) for ...  -  ‎Oct 26, 2009‎
...interfere with the absorption of drugs for which gastric pH is important for bioavailability (eg, ampicillin esters, digoxin, iron salts, ketoconazole). ... Reuters

FDA Sends Letter to Sanofi-Aventis Regarding Uroxatral Promotion  -  ‎Oct 28, 2009‎
...in patients with moderate or severe hepatic impairment and co-administration with potent CYP3A4 inhibitors (eg, ketoconazole, itraconazole, ritonavir). ... PharmaLive.com (press release)

Market Watch  -  ‎Nov 5, 2009‎
The lower dose (2.5 mg) also is recommended for patients taking strong CYP3A4/5 inhibitors (eg, ketoconazole, atazanavir, clarithromycin, indinavir, ... The Hospitalist Online

New drug for type 2 diabetes  -  ‎Oct 29, 2009‎
Interactions: Potentiated by strong CYP3A4/5 inhibitors (eg, ketoconazole, atazanavir, clarithromycin, indinavir, itraconazole, nefazodone, nelfinavir, ... Clinical Advisor

Novartis drug Tasigna(R) meets primary endpoint in pivotal trial against ...  -  ‎Oct 19, 2009‎
Examples of commonly used drugs that may significantly interact with Gleevec include ketoconazole, acetaminophen, warfarin, erythromycin, and phenytoin. ... Reuters

Khi vùng ngá»±c phụ nữ 'rậm' lông?  -  ‎Nov 12, 2009‎
...chỉ định thuốc hạn chế quá trình tiết ra hormone sinh dục nam như spironolactone, cyproterone acetate, flutamide, hoặc thuốc tránh thai, ketoconazole. ... Báo Đất Việt

Differential effects of ketoconazole on exposure to temsirolimus...  -  Mar 26, 2008
Intravenous (iv) temsirolimus, a novel inhibitor of mammalian target of rapamycin, is approved for the treatment of advanced renal cell carcinoma and is ... Nature.com

Ketoconazole Oral : Uses, Side Effects, Interactions, Pictures,...  -  Jan 8, 2007
This information is generalized and not intended as specific medical advice. Consult your healthcare professional before taking or discontinuing any drug or ... WebMD

Ketoconazole Oral : Uses, Side Effects, Interactions, Pictures,...  -  May 20, 2008
This information is generalized and not intended as specific medical advice. Consult your healthcare professional before taking or discontinuing any drug or ... WebMD

Ketoconazole Oral : Uses, Side Effects, Interactions, Pictures,...  -  Oct 10, 2008
This information is generalized and not intended as specific medical advice. Consult your healthcare professional before taking or discontinuing any drug or ... WebMD

Learn about Ketoconazole Topical from Consumer Reports Health.  -  Jan 4, 2005
Ketoconazole cream is used to treat tinea corporis (ringworm; fungal skin infection that causes a red scaly rash on different parts of the body), ... consumerreports.org

Ketoconazole (Topical).(Drug overview)  -  May 1, 2006
Ketoconazole (kee-toe-KOE-na-zole) is used to treat infections caused by a fungus or yeast. It works by killing the fungus or yeast or preventing its growth ... Free with registration - USP DI-Volume II, Advice for the... - AccessMyLibrary.com

Learn about Ketoconazole from Consumer Reports Health.  -  Jan 4, 2005
Ketoconazole may cause liver damage. Tell your doctor if you drink or have ever drunk large amounts ... Full Alert. Ketoconazole is used to treat fungal ... consumerreports.org

… Fluconazole Itraconazole Ketoconazole Antineoplastic Ketoconazole D  -  Aug 1, 2006
Azole antifungals are used to treat serious fungus infections that may occur in different parts of the body. These medicines may also be used for other ... Free with registration - USP DI-Volume II, Advice for the... - AccessMyLibrary.com

… [257] - Activity of Dustasteride Plus Ketoconazole in Hormone...  -  Feb 23, 2007
Introduction: Ketoconazole is commonly used as a secondary hormonal therapy ... Conclusions: Dutasteride in combination with ketoconazole is associated with ... UroToday International Journal

Ketoconazole (Topical).  -  Oct 27, 2005
Ketoconazole (kee-toe-KOE-na-zole) is used to treat infections caused by a fungus or yeast. It works by killing the fungus or yeast or preventing its growth ... Free with registration - USP DI-Volume II, Advice for the... - AccessMyLibrary.com

Dreadful dandruff  -  Sep 3, 2006
...active ingredients (selenium sulphide, cold tar, sulphur, salicylic acid, zinc pyrithione, ketoconazole) to find the best suited for any one individual. ... Malaysia Star

Ketoconazole 2% Foam Effective and Safe for Seborrheic Dermatitis: …  -  Feb 5, 2008
By Bruce Sylvester. SAN ANTONIO, TX -- Feb. 5, 2008 -- Ketoconazole 2% foam treatment is effective and safe, and is suitable for treatment of patients 12 ... DG News

A novel foam formulation of ketoconazole 2% for the treatment of …  -  Oct 1, 2007
Background: A novel topical foam formulation of ketoconazole has been developed for use on the scalp, body, and face. Objective: To evaluate the efficacy ... $4.95 - Journal of Drugs in Dermatology - ECNext

Site of Action of Low Dose Ketoconazole on Androgen Biosynthesis in …  -  Apr 1, 2005
Department of Medicine, Division of Endocrinology, The Milton S. Hershey Medical Center, The Pennsylvania State University (RJS) Hershey, Pennsylvania 17033 ... Journal of Clinical Endocrinology and...

Low Dose and High Dose Ketoconazole Demonstrate Similar Outcomes …  -  Sep 12, 2006
BERKELEY, CA (UroToday.com) - Patients on androgen deprivation therapy (ADT) for prostate cancer (CaP) eventually progress with a rising PSA. ... UroToday International Journal

Cougar Biotechnology Presents Positive CB7630 (Abiraterone Acetate) …  -  Jun 2, 2008
Seventeen patients (71%) had received prior treatment with ketoconazole ... Fifteen (79%) of these 19 patients had discontinued ketoconazole use due to ... RedOrbit

… in South India: Successful treatment with ketoconazole.(Letter To...  -  Sep 1, 2007
The patients were treated with oral ketoconazole (200mg twice daily for patients ... The efficacy of ketoconazole in different doses for variable periods in ... Free with registration - Indian Journal of Dermatology, Venereolo... - AccessMyLibrary.com

Low Dose And High Dose Ketoconazole Demonstrate Similar Outcomes …  -  Sep 15, 2006
Patients on androgen deprivation therapy (ADT) for prostate cancer (CaP) eventually progress with a rising PSA. Definitions of androgen-independence vary, ... Medical News Today - Medical News Today (press release)

Ketoconazole Side Effects from Consumer Reports Health.  -  Jan 4, 2005
Ketoconazole may cause liver damage. Tell your doctor if you drink or have ever drunk large amounts ... Full Alert. Ketoconazole may cause liver damage. ... consumerreports.org

Establishing a ketoconazole suppression test for verifying testosteron...  -  Jul 1, 2006
The ratio of urinary testosterone (uT) to epitestosterone (T/EpiT) is used to disclose testosterone (T) administration in the doping control of sports, ... Journal of Clinical Endocrinology and...

Use of ketoconazole to probe the pathogenetic importance of 1,25- …  -  Sep 1, 2008
Ketoconazole was used to probe the pathogenetic importance of the serum 1,25-dihydroxyvitamin D [1,25-(OH)2D] concentration in 19 patients with well ... Journal of Clinical Endocrinology and...

B3 (Au), C (US)  -  Sep 18, 2007
Ketoconazole is a synthetic antifungal drug used to prevent and treat ... Ketoconazole is very lipophilic, which leads to accumulation in fatty tissues. ... chemie.de

How to take Ketoconazole Topical from Consumer Reports Health.  -  Jan 4, 2005
...tell your doctor and pharmacist if you are allergic to ketoconazole or any other medications, creams, or shampoos. If you will be using the cream, ... consumerreports.org

Ketoconazole cleanser: DermaPet[R].(SMALL ANIMAL)  -  Oct 1, 2007
TrizULTRA+KETO features 0.15 percent ketoconazole in USP TrizEDTA, thus combining antifungal properties with an antibacterial cleanser. ... Free with registration - DVM Newsmagazine - AccessMyLibrary.com

Psychopharmacology; Ketoconazole synergizes with allopregnanolone …  -  Mar 8, 2005
They concluded that "fluoxetine, desipramine, ketoconazole, ... Ketoconazole, fluoxetine, or desipramine synergized with allopregnanolone." ... Pay-Per-View - Science Letter - Factiva, from Dow Jones

Phase III clinical trial of Extina (ketoconazole) Foam 2%.(PIPLELINE ...  -  Nov 1, 2006
Connetics Corporation recently announced positive results of a Phase III clinical trial of Extina (ketoconazole) Foam 2% in the treatment of seborrheic ... Free with registration - Journal of Drugs in Dermatology - AccessMyLibrary.com

Treatment of onychomycosis with nail avulsion and topical ketoconazole...  -  Jan 1, 2008
A new, effective treatment alternative for onychomycosis is presented. It involves the avulsion of the affected toenails and daily application of topical ... Journal of the American Podiatric...

Extina (ketoconazole) Foam.(NEW DRUGS)(FDA drug apporval)(Brief …  -  Aug 6, 2007
Stiefel Laboratories, Coral Gables, Fla., (888) 784-3335, has received FDA approval for Extina (ketoconazole) Foam 2% for the treatment of seborrheic ... Free with registration - Drug Topics - AccessMyLibrary.com

Psychopharmacology; Ketoconazole synergizes with allopregnanolone …  -  Mar 7, 2005
They concluded that "fluoxetine, desipramine, ketoconazole, ... Ketoconazole, fluoxetine, or desipramine synergized with allopregnanolone." ... Pay-Per-View - OBGYN & Reproduction Week - Factiva, from Dow Jones

Ketoconazole shampoo: DermaPet[R].(SMALL ANIMAL)  -  Oct 1, 2007
Mal-A-Ket Shampoo features 1 percent ketoconazole, 2 percent chlorhexidine and 2 percent acetic acid. The result is a shampoo that is pleasant-smelling, ... Free with registration - DVM Newsmagazine - AccessMyLibrary.com

Psychopharmacology; Ketoconazole synergizes with allopregnanolone …  -  Mar 7, 2005
They concluded that "fluoxetine, desipramine, ketoconazole, ... Ketoconazole, fluoxetine, or desipramine synergized with allopregnanolone." ... Pay-Per-View - Mental Health Weekly Digest - Factiva, from Dow Jones

Barrier gets US FDA approval for dermatitis gel  -  Aug 1, 2006
Xolegel is the first prescription gel formulation of ketoconazole approved in the US. Xolegel is Barrier's second product approved by the FDA this year and ... pharmabiz.com

Psychopharmacology; Ketoconazole synergizes with allopregnanolone …  -  Mar 10, 2005
They concluded that "fluoxetine, desipramine, ketoconazole, ... Ketoconazole, fluoxetine, or desipramine synergized with allopregnanolone." ... Pay-Per-View - Women's Health Weekly - Factiva, from Dow Jones

Azoles for ringworm of the scalp or beard  -  Apr 24, 2007
You can use ketoconazole shampoo along with pills to treat ringworm of the ... You should not take ketoconazole pills within 2 hours of taking antacids, ... MSN Health & Fitness

Barrier Therapeutics Receives FDA Approval of Xolegel(TM) Gel for the...  -  Jul 28, 2006
Xolegel is the first prescription gel formulation of ketoconazole approved in the US. Xolegel is Barrier's second product approved by the FDA this year and ... Genetic Engineering News - Genetic Engineering News (press release)

GU Cancers Symposium - ASCO ASTRO SUO - 2008 - Secondary …  -  Feb 15, 2008
Ketoconazole and hydrocortisone show a 27-63% PSA response rate. ... Ketoconazole is metabolized by CYP3A4 and thus its use can interfere with metabolism of ... UroToday International Journal

Psychopharmacology; Ketoconazole synergizes with allopregnanolone …  -  Mar 7, 2005
They concluded that "fluoxetine, desipramine, ketoconazole, ... Ketoconazole, fluoxetine, or desipramine synergized with allopregnanolone." ... Pay-Per-View - Health & Medicine Week - Factiva, from Dow Jones

Ketoconazole plus chlorhexidine: DermaPet[R].(SMALL ANIMAL)  -  Oct 1, 2007
TrizEDTA[TM] Plus features 0.15 percent chlorhexidine and USP tris-edta, thus combining the gram-negative activity of TrizEDTA with the gram-positive ... Free with registration - DVM Newsmagazine - AccessMyLibrary.com

Article: Ketoconazole available as gel.(Products) - Skin & Allergy...  -  Dec 1, 2006
Ketoconazole available as gel.(Products) ... find Skin & Allergy News articles. Xolegel (ketoconazole) gel 2% is indicated for the topical treatment of ... Pay-Per-View - Skin & Allergy News - HighBeam Research

Barrier Therapeutics Receives Regulatory Approval to Market Xolegel...  -  Mar 8, 2007
Barrier Therapeutics currently markets three pharmaceutical products in the United States: Xolegel TM (ketoconazole, USP) Gel, 2%, for seborrheic dermatitis ... ccnmatthews.com

Press Release: DiObex Announces Presentation of Scientific Poster at ...  -  Apr 1, 2008
DIO-902 is an oral, single enantiomer of ketoconazole, a common anti-fungal drug. ... It is a single enantiomer of racemic ketoconazole which suppresses ... Pay-Per-View - PR Newswire - HighBeam Research

FDA approved Xolegel Gel for the treatment of seborrheic dermatitis.(...  -  Oct 1, 2006
Xolegel Gel 2% is a formulation of topical 2% ketoconazole. This formulation is a waterless gel that is approved for once daily application in adults and ... Free with registration - Journal of Drugs in Dermatology - AccessMyLibrary.com

Extina (ketoconazole) Foam.  -  Aug 6, 2007
Extina (ketoconazole) Foam. Stiefel Laboratories, Coral Gables, Fla., (888) 784-3335, has received FDA approval for Extina (ketoconazole) Foam 2% for the ... $9.94 - Drug Topics - Alacra Store

Is abiraterone acetate well tolerated and effective in the treatment...  -  Aug 8, 2008
Ketoconazole (a nonselective, competitive inhibitor of several cytochrome P450 ... (2008) Impact of prior ketoconazole therapy on response proportion to ... Nature.com

Ketoconazole available as gel.(Products)  -  Dec 1, 2006
Xolegel (ketoconazole) gel 2% is indicated for the topical treatment of seborrheic dermatitis in immunocompetent adults and children aged 12 years or older. ... Pay-Per-View - Skin & Allergy News - Factiva, from Dow Jones

Alfuzosin (Systemic).  -  Jul 28, 2005
Itraconazole (eg, Sporanox) or Ketoconazole (eg, Nizoral) or Ritonavir (eg, Norvir) -- These medicines may cause there to be more alfuzosin in your body and ... Free with registration - USP DI-Volume II, Advice for the... - AccessMyLibrary.com

Extina (ketoconazole) Foam.(NEW DRUGS)(FDA drug apporval)(Brief …  -  Aug 6, 2007
Stiefel Laboratories, Coral Gables, Fla., (888) 784-3335, has received FDA approval for Extina (ketoconazole) Foam 2% for the treatment of seborrheic ... $4.95 - Drug Topics - ECNext

Cytokinetics Provides Updates From Phase I Clinical Trials of CK- …  -  Jun 13, 2008
The primary objective of this study is to evaluate the effect of ketoconazole (a potent inhibitor of the drug-metabolizing enzyme, cytochrome P450 (CYP3A4) ... Lifescience-online

Connetics to Resume Extina Development with New Phase III Trial.  -  Jun 8, 2005
Previously announced results from Connetics' Phase III clinical trial with Extina demonstrated non-inferiority to Nizoral(R) (ketoconazole) 2% Cream as ... $4.95 - Business Wire - ECNext

Neonatal acne receives new name.(Clinical Rounds)  -  Jun 1, 2007
If the parents are concerned, twice-daily 2% ketoconazole cream "works beautifully and very rapidly," according to Dr. Kress, chief of pediatric dermatology ... Free with registration - Skin & Allergy News - AccessMyLibrary.com

Cougar Biotechnology Presents CB7630 Clinical Data  -  Oct 29, 2007
Sixty-three percent had received prior treatment with ketoconazole, a drug used off label as a secondary hormonal therapy. Treatment with CB7630 was found ... FDA news - FDA news (subscription)

DI-VE - Lifestyle details  -  Mar 3, 2008
Both Ketoconazole and Zinc Pyrithione work wonders when combined together. ... An ingenious product since it combines both Ketoconazole and Zinc Pyrithione ... di-ve.com

Mold may cause excessive coughing  -  Oct 7, 2007
The doctor finally gave me ketoconazole 2 percent and ketoconazole 200-milligram tablets, which he said was treatment for mold. ... $3.50 - Intelligencer, The - NewsBank

Barrier Therapeutics gains FDA approval for Sebazole NDA.(Food and …  -  Dec 19, 2005
...that the Food and Drug Administration has accepted its New Drug Application for Sebazole (ketoconazole USP 2%), which the firm submitted in September. ... $4.95 - Pharma Marketletter - ECNext

DiObex Presents Phase 2a Data of DIO-902 Demonstrating Trends of …  -  Jun 25, 2007
It is a single enantiomer of racemic ketoconazole which suppresses cortisol production by inhibiting the 11 beta hydroxylase enzyme, the terminal step in ... $4.95 - PR Newswire - ECNext

What's the best treatment for cradle cap?(CLINICAL INQUIRIES)  -  Mar 1, 2007
Ketoconazole (Nizoral) shampoo appears to be a safe and efficacious ... Based on small studies, ketoconazole appears safe and effective for infants. ... $4.95 - Journal of Family Practice - ECNext

Antifungals, Azole (Systemic).(Drug overview)  -  May 1, 2006
Didanosine (eg, ddI, Videx) -- Use of didanosine with itraconazole or ketoconazole may decrease the effects of itraconazole or ketoconazole, as well as of ... Free with registration - USP DI-Volume II, Advice for the... - AccessMyLibrary.com

Nizoral Oral : Uses, Side Effects, Interactions, Pictures, Warnings &...  -  Sep 30, 2008
Itraconazole and ketoconazole may slow down how quickly your liver processes ... The amount of itraconazole and ketoconazole in your blood may increase and ... WebMD

… Phase III Clinical Trial of Extina(R) (Ketoconazole) Foam, 2%; NDA  -  Aug 28, 2006
Ketoconazole is used to treat a variety of fungal infections, including seborrheic dermatitis. Seborrheic dermatitis is a chronic, recurrent skin condition ... Free with registration - Business Wire - AccessMyLibrary.com

Barrier Therapeutics Introduces Dual-Component Xolegel CorePak(TM) …  -  Jul 28, 2008
..."By providing the hydrocortisone and ketoconazole gels separately in one ... Xolegel Gel is a patented topical formulation of 2% ketoconazole in a ... RedOrbit

Press Release: DiObex Takes Novel Cortisol Synthesis Inhibitor Into …  -  Feb 22, 2006
DIO-902 (2S,4R ketoconazole) is one of the two enantiomers contained within the ... "The data generated for racemic ketoconazole in patients with type 2 ... Pay-Per-View - PR Newswire - HighBeam Research

Company Profile Report  -  Mar 29, 2008
Altana Pharma Ketoconazole; Doak Dermatologics Selseb (Selenium Sulfide) ... Altana Pharma Oxistat (Oxiconazole Nitrate); Altana Pharma Ketoconazole ... $50.00 - Revere Reports - Revere

Interactions  -  Apr 25, 2006
The problem turned out to be related to simultaneous administration of the antifungal drug ketoconazole. Both of these drugs were metabolized by the same ... Pay-Per-View - Washington Post - ProQuest Archiver

Barrier Therapeutics Announces Issuance of Xolegel(TM) Patent  -  Feb 20, 2007
Xolegel (ketoconazole, USP) Gel, 2% is a cosmetically elegant, ... Xolegel Gel is a topical formulation of 2% ketoconazole, an antifungal agent, ... Web Services Journal - Web Services Journal

Competitors by Product Report  -  Dec 16, 2006
NIZORAL Cream (Ketoconazole); NIZORAL Shampoo (Ketoconazole) ... Ciclopirox Olamine Cream; Ciclopirox Topical Suspension; Ketoconazole. Dermatoses ... $75.00 - Revere Reports - Revere

Barrier Therapeutics Introduces New Xolegel Duo TM Offering at the …  -  Aug 2, 2007
Xolegel Gel is a topical formulation of 2% ketoconazole, an antifungal agent, in a translucent, non-greasy gel that provides powerful relief comparable to ... marketwire.com

Experimental Drug Improves Glycemic Control, Lipids in Type 2...  -  Jun 4, 2007
Dubbed DIO-902, an enantiomer of ketoconazole, the compound was ... Dr. Welles noted that ketoconazole, a racemic combination of two enantiomers, ... DG News

Seborrheic dermatitis: an overview.(disease overview)(Disease/Disorder...  -  Jul 1, 2006
...(29) Patients also may use a 2 % ketoconazole or a fluconazole shampoo. (29,30,35) Some azoles (e.g., itraconazole [Sporanox], ketoconazole) also have ... Free with registration - American Family Physician - AccessMyLibrary.com

â—‹â•® 腳丫å•?題多》 香港腳æ?”癢難è€?~ 難看å?ˆç—›è‹¦  -  Jul 15, 2008
...藥�有多種,包括ketoconazole�allyamine�tolnaftate 等,且治療周期至少�續 ... 一般常用的��藥包括Griseofulvin �Ketoconazole。Griseofulvin �抑制黴�細胞 ... udn.com

Press Release: DiObex Begins Dosing Patients in Phase 2b Trial of...  -  Sep 26, 2007
DIO-901 has received ... Drug Administration. DIO-902 is a single enantiomer ... ketoconazole and is a novel cortisol synthesis inhibitor. Abnormalities ... ... Pay-Per-View - PR Newswire - HighBeam Research

Dermatology; Connetics reports positive results from second Phase III...  -  Sep 26, 2006
Results demonstrated Extina was not inferior to Nizoral (ketoconazole), 2%, ... Ketoconazole is used to treat a variety of fungal infections, ... Pay-Per-View - Life Science Weekly - Factiva, from Dow Jones

Rx FOR READERS  -  Aug 12, 2005
Ketoconazole (Nizoral) should not be given long term, and I generally do not ... Concomitant use of ketoconazole or itraconazole with sildenafil (Viagra) ... Pay-Per-View - Jerusalem Post - ProQuest Archiver

The making of a pharma brand  -  Sep 15, 2006
Whereas the prescribed brand had two percent Ketoconazole, the advertised ... Another brand with the original Ketoconazole 2%, along with an additional ... Express Pharma

Seborrheic dermatitis: an overview.(disease overview)(Disease/Disorder...  -  Jul 1, 2006
...(29) Patients also may use a 2 % ketoconazole or a fluconazole shampoo. (29,30,35) Some azoles (e.g., itraconazole [Sporanox], ketoconazole) also have ... $4.95 - American Family Physician - ECNext

Competitors by Product Report  -  Aug 2, 2008
Products:. Xolegel (Ketoconazole). Johnson & Johnson (JNJ) Products:. NIZORAL Cream (Ketoconazole); NIZORAL Shampoo (Ketoconazole) ... $75.00 - Revere - Alacra Store

Drug/Medical Device  -  Dec 16, 2006
Ketoconazole, Tinea Corporis, Tinea Cruris, Tinea Pedis, Tinea Versicolor, Cutaneous Candidiasis, Seborrheic Dermatitis, Nausea and/or Vomiting, ... $70.00 - Revere Reports - Revere

Competitors by Product Report  -  Aug 2, 2008
Products:. Xolegel (Ketoconazole). Johnson & Johnson (JNJ) Products:. NIZORAL Cream (Ketoconazole); NIZORAL Shampoo (Ketoconazole) ... $75.00 - Revere Reports - Revere

Newborn skin: Part I. common rashes.  -  Jan 1, 2008
One meta-analysis found that topical ketoconazole (Nizoral, brand no longer available in the united States) and steroid creams are effective in the ... Free with registration - American Family Physician - AccessMyLibrary.com

Personal digital assistant-based drug reference software as tools to ...  -  Jan 25, 2005
The final set—erythromycin and ketoconazole—was chosen to test whether the software could predict a potentially life-threatening drug interaction (cardiac ... Nature.com

Barrier Therapeutics Announces Third Quarter 2006 Financial Results  -  Oct 31, 2006
Xolegel (ketoconazole, USP) Gel, 2%, has been shipped to the major wholesalers. Xolegel is a waterless gel formulation containing 2.0% of the antifungal ... CNNMoney.com

FDA Approves Extina(R) for the Treatment of Seborrheic Dermatitis  -  Jul 17, 2007
Extina(R) (ketoconazole) Foam, 2% is indicated for the topical treatment of seborrheic dermatitis in immunocompetent patients 12 years of age and older. ... RedOrbit

FDA approves Extina for seborrheic dermatitis  -  Jul 18, 2007
Extina(R) (ketoconazole) Foam, 2% is indicated for the topical treatment of seborrheic dermatitis in immunocompetent patients 12 years of age and older. ... News-Medical.net

Fighting fungal disease: updates on topical, oral treatments.(Special...  -  Dec 1, 2005
Ketoconazole covers a dermatophyte fungus like griseofulvin, ... "Today, dermatologists do not often use ketoconazole because we know about one out of 10000 ... Free with registration - Dermatology Times - AccessMyLibrary.com

The Effect of Granisetron on in Vitro Metabolism of Doxorubicin,...  -  May 10, 2005
Positive controls were ketoconazole, 20 M, a potent inhibitor of CYP3A metabolism ... Ketoconazole prevented the breakdown of both irinotecan and etoposide, ... RedOrbit

Tinea versicolor is harmless but can recur  -  Apr 19, 2007
Prescription treatments include ketoconazole 2 percent shampoo applied to ... Ketoconazole 400 mg as a single oral dose results in short-term cure in 90 ... Honolulu Advertiser

Drug Metabolism; Metabolism of alfentanil by CYP3A enzymes …  -  Apr 26, 2005
..."Effects of the CYP3A inhibitors troleandomycin and ketoconazole were also determined," the investigators wrote in the journal Drug Metabolism and ... Pay-Per-View - Science Letter - Factiva, from Dow Jones

Antifungal activity of some Brazilian Hypericum species.  -  Mar 1, 2005
The antifungal agents ketoconazole (Janssen Pharmaceutical) and amphotericin B (Sigma Chemical Co.) were included in the assay as positive controls. ... Free with registration - Phytomedicine: International Journal of... - AccessMyLibrary.com

Seborrheic Dermatitis Therapy; Positive phase III results reported...  -  Jan 17, 2005
Sebazole is a topical formulation consisting of 2.0% ketoconazole, an antifungal agent, ... Compared to currently approved ketoconazole cream products, ... Pay-Per-View - Pharma Business Week - Factiva, from Dow Jones

Seborrheic Dermatitis Therapy; Positive phase III results reported...  -  Jan 21, 2005
Sebazole is a topical formulation consisting of 2.0% ketoconazole, an antifungal agent, ... Compared to currently approved ketoconazole cream products, ... Pay-Per-View - Drug Week - Factiva, from Dow Jones

Seborrheic Dermatitis; Barrier Therapeutics receives US FDA approval...  -  Aug 30, 2006
Xolegel is the first prescription gel formulation of ketoconazole approved in the US. Xolegel is Barrier's second product approved by the FDA this year and ... Pay-Per-View - Immunotherapy Weekly - Factiva, from Dow Jones

Press Release: Barrier Therapeutics to Present Data on Azoline and …  -  Feb 18, 2005
Barrier Therapeutics, Inc., an emerging ... combination topical agent containing ketoconazole, an antifungal agent ... in middle age. ... Pay-Per-View - PR Newswire - HighBeam Research

Seborrheic Dermatitis; Barrier Therapeutics receives US FDA approval...  -  Sep 1, 2006
Xolegel is the first prescription gel formulation of ketoconazole approved in the US. Xolegel is Barrier's second product approved by the FDA this year and ... Pay-Per-View - Drug Week - Factiva, from Dow Jones

Seborrheic Dermatitis Therapy; Positive phase III results reported...  -  Jan 22, 2005
Sebazole is a topical formulation consisting of 2.0% ketoconazole, an antifungal agent, ... Compared to currently approved ketoconazole cream products, ... Pay-Per-View - Obesity, Fitness & Wellness Week - Factiva, from Dow Jones

Drug Metabolism; Metabolism of alfentanil by CYP3A enzymes …  -  Apr 30, 2005
..."Effects of the CYP3A inhibitors troleandomycin and ketoconazole were also determined," the investigators wrote in the journal Drug Metabolism and ... Pay-Per-View - Obesity, Fitness & Wellness Week - Factiva, from Dow Jones

抗屑洗髮精å?¯å¹«ä½ æˆ°ç—˜  -  Aug 6, 2006
...皮屑芽孢�毛囊炎�用一般治療�春痘的抗生素效果�佳,必須使用治療黴�的�分� 是ketoconazole�能見效。�間的抗屑洗髮精也有這種�分,如果患者背上長的剛好是這類 ... 自由時報

Pharmacological management of secreting pituitary tumors.( …  -  Feb 1, 2007
Ketoconazole, an antifungal agent that blocks adrenal steroid synthesis, ... Ketoconazole enhances the effect of anticoagulant drugs such as warfarin. ... Free with registration - Journal of Neuroscience Nursing - AccessMyLibrary.com

Calcium.(dosage and administration)  -  Jun 1, 2006
Ketoconazole: Concomitant use may result in decreased effectiveness of ketoconazole. Clinical Management: Concurrent administration of ketoconazole and ... Free with registration - PDR for Herbal Medicines - AccessMyLibrary.com

The keys to identifying and managing fungal infections of the lungs:...  -  Mar 1, 2005
The triazole antifungals include ketoconazole, itraconazole, fluconazole, and voriconazole. Because of poor absorption and significant drug interactions, ... $4.95 - Journal of Respiratory Diseases - ECNext

Declining Gastrointestinal Opportunistic Infections in HIV-Infected …  -  Jan 19, 2005
Ketoconazole-resistant Candida esophagitis in patients with acquired ... Fluconazole compared with ketoconazole for the treatment of Candida esophagitis in ... Nature.com

Seborrheic Dermatitis - Symptoms, Diagnosis, Treatment of Seborrheic ...  -  Jul 18, 2007
Shampoos or lotions containing selenium, ketoconazole, or corticosteroids may be prescribed for severe cases. To apply shampoos, part the hair into small ... New York Times

Brand Names/Synonyms:
Ketoconazole is also known by the following brand names and/or synonymsDRG-0073; Extina; Fungarest; Fungoral; KETOCONAZOLE, 99%; KW-1414; Ketocanazole; Ketoconazol; Ketoconazol [Inn-Spanish]; Ketoconazole; Ketoconazole [Usan:Ban:Inn:Jan]; Ketoconazolum [Inn-Latin]; Ketoderm; Ketoisdin; Ketozole; Nizoral; Nizoral Cream; Nizoral Shampoo; Nizoral a-D; Nizoral a-D Shampoo; Orifungal; Orifungal M; Panfungol

Drug Category:
Ketoconazole is categorized under the following by the FDA: Antifungals; Antifungals; ATC:D01AC08; ATC:G01AF11; ATC:J02AB02

Dosage Forms:
Oral tablets, Shampoo, Cream, Suspension;

Absorption:
Moderate

Interactions:
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Chemical IUPAC Name:
1-[4-[4-[[2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]piperazin-1-yl]ethanone





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