Levofloxacin

This page contains recent news articles, when available, and an overview of Levofloxacin but does not offer medical advice. You should contact your physician with regard to any health issues or concerns.


Overview:

Levofloxacin
(when available)

Pharmacology and use:
Levofloxacin, a fluoroquinolone antiinfective, is the optically active L-isomer of ofloxacin. Levofloxacin is used to treat bacterial conjunctivitis, sinusitis, chronic bronchitis, community-acquired pneumonia and pneumonia caused by penicillin-resistant strains of Streptococcus pneumoniae, skin and skin structure infections, complicated urinary tract infections and acute pyelonephritis. For the treatment of Bacterial infection of; Respiratory tract, Urinary tract, GI, CNS and Immuno compromised patients caused by: S.pneumoniae, H.influenzae, M.catarrhalis, S.aureus, H.parainfluenzae, P.aeruginosa, S.marcescens, E.coli, K.pneumoniae, C.pn

Mechanism Of Action:
Levofloxacin inhibits bacterial type II topoisomerases, topoisomerase IV and DNA gyrase. Levofloxacin, like other fluoroquinolones, inhibits the A subunits of DNA gyrase, two subunits encoded by the gyrA gene. This results in strand breakage on a bacterial chromosome, supercoiling, and resealing; DNA replication and transcription is inhibited.

News Articles on Levofloxacin

Hypoglycemia Associated with the Use of Levofloxacin  -  ‎Jan 4, 2010‎
Levofloxacin 750 mg was administered orally on hospital day 1 for the treatment of CAP and was ordered to be administered every 48 hours. On hospital day 3, ... Medscape

Trio says Levaquin caused tendon injuries  -  ‎Dec 17, 2009‎
Aventis, the largest manufacturer of levofloxacin in Europe, agreed to two epidemiological studies in Europe regarding the antibiotic's tenotoxic effects. ... West Virginia Record

Generic Levaquin Is in the Pipeline  -  ‎Dec 14, 2009‎
Washington, DC: The potential for adverse responses to Levaquin increases with the expiry of Johnson & Johnson's (J&J) patent for levofloxacin, ... Lawyers and Settlements

Case 40-2009 — A 29-Year-Old Man with Fever and Respiratory Failure  -  ‎Dec 23, 2009‎
Levofloxacin was prescribed, and he was sent home. During the next 2 days, nausea and vomiting developed, with blood-tinged emesis. One day before admission ... New England Journal of Medicine (subscription)

Antibiotic Therapy in Elderly Patients with Acute Exacerbation of Chronic ...  -  ‎Dec 21, 2009‎
Patient stratification in the management of acute bacterial exacerbation of chronic bronchitis: the role of levofloxacin 750 mg. Eur. Respir. ... Medscape

Florida TB case most extensively drug-resistant yet in US  -  ‎Dec 29, 2009‎
...second-line therapies are available and include fluoroquinolones (levofloxacin, moxifloxacin, or gatifloxacin); amikacin, kanamycin , or capreomycin ... Pediatric SuperSite

Risk of Endophthalmitis After Intravitreal Drug Injection When Topical ...  -  ‎Dec 14, 2009‎
Puustjärvi T, Teräsvirta M, Nurmenniemi P, Lokkila J, Uusitalo H. Penetration of topically applied levofloxacin 0.5% and ofloxacin 0.3% into the vitreous of ... Archives of Ophthalmology

Rib-X Pharmaceuticals Enters into Collaborative Agreement on Delafloxacin with ...  -  ‎Dec 15, 2009‎
...delafloxacin has been shown to be at least 32-fold more potent than levofloxacin, ciprofloxacin, gatifloxacin and moxifloxacin. ... PR Newswire (press release)

Kenapa Bisa Kena Penyakit Lichen Planus?  -  ‎Jan 3, 2010‎
Untuk saat ini saya mengkonsumsi obat Cravit Levofloxacin 500 mg (antibiotik), Sulcolon Sulfasalazine 500 mg,Galflux Domperidone 10 mg, ... Detikcom

Daiichi Sankyo Submits Application for Approval of Levofloxacin Hydrate ...  -  14 Nov 2009
Cravit®, an oral Levofloxacin Hydrate agent, already is a widely accepted treatment in formulations of 500mg and 250mg tablets and as a 10% fine granular ... Ethio Planet News

Oculus Innovative Sciences Inc. Reports Operating Results (10-Q)  -  ‎Nov 10, 2009‎
At visit three (end of treatment) the clinical success rate for patients treated with Microcyn alone was 77.8% compared to 61.1% for the Levofloxacin plus ... GuruFocus.com

When Drugs for Ulcers Don't Work  -  ‎Nov 9, 2009‎
One is levofloxacin triple therapy, which consists of a PPI (proton-pump inhibitor) along with amoxicillin and levofloxacin. This regimen has been reported ... New York Times

Band-Aid Won't Stop Generic Bleeding at Johnson & Johnson  -  ‎Nov 11, 2009‎
Aciphex (rabeprazole) for heartburn and acid reflux, and Levaquin (levofloxacin), an antibiotic for urinary tract infections. ... BNET

Levaquin Trial Consolidation for Bellwether Cases Opposed by J&J  -  ‎Nov 11, 2009‎
Levaquin (levofloxacin), which is part of a class of medications known as fluoroquinolones, was approved by the FDA in December 1996. ... AboutLawsuits.com

Recurrent cellulitis following buttock augmentation  -  ‎Nov 3, 2009‎
She was discharged home on levofloxacin (Levaquin) 500 mg po daily for two weeks and clarithromycin (Biaxin) 500 mg po twice daily for at least six months. ... Clinical Advisor

New H. pylori Regimen Wins LAC and LOAD Trial  -  ‎Oct 27, 2009‎
The new four-drug treatment, known as LOAD, comprises levofloxacin, omeprazole (Prilosec), nitazoxanide (Alinia), and doxycycline. ... MedPage Today

New Advances and Insights in Gastroenterology Presented at College's 74th ...  -  ‎Oct 21, 2009‎
...was eradicated in 95 percent patients who took a 7-day course of combination therapy with levofloxacin, omeprazole, nitazoxanide (Alinia(R)) and ... Reuters

The Fluoroquinolone Antibiotic Levaquin® has Allegedly been Linked to ...  -  ‎Oct 29, 2009‎
Dallas, TX (PRWEB) October 29, 2009 -- Levaquin (a brand-name of Levofloxacin) is a powerful antibiotic in a class known as fluroquinones, and is prescribed ... PR Web (press release)

Questions raised about Human Genome Science's anthrax vaccine  -  ‎Oct 23, 2009‎
...“The combination efficacy studies demonstrated very high efficacies (nearly 100%) of levofloxacin in NZW rabbits and ciprofloxacin in cynomolgus monkeys ... Bizjournals.com

Karnataka DC seizes stocks of Ofloxacin tablets valued at Rs 1.20 lakh  -  ‎Oct 20, 2009‎
Levofloxacin is also an antibiotic to treat bacterial infections. It is in a class of antibiotics called fluoroquinolones which includes ciprofloxacin, ... pharmabiz.com

Travel in the Amazon: Health Tips for the Discerning Tourist  -  ‎Oct 27, 2009‎
Antibiotics such as levofloxacin or ciprofloxacin generally work well in Perú, although children and some adults are better treated with azithromycin. ... Living in Peru (blog)

다ì?´ì?´ì°Œ ì‚°êµ?, 레보프ë¡?사신 주사용 허가 ì‹ ì²­  -  ‎Oct 30, 2009‎
...김윤ì˜? 기ìž? 다ì?´ì?´ì°Œ ì‚°êµ?는 새로운 퀴놀론계 í•­ìƒ?ì œ 레보프ë¡?사신(Levofloxacin)ì?˜ 주사 제를 ì?¼ë³¸ì—?서 시íŒ? 허가를 신청했다. ì?´ í•­ìƒ?제는 ìž„ìƒ? 연구ì—?서 í??ë ´, ... 메디포뉴스

휴온스-유ì˜?제약, 'íƒ?루신캡ìŠ?' ê³µë?™íŒ?매  -  ‎Nov 4, 2009‎
...ë˜?한 지난 8ì›”ì—?ë?„ ì?¼í™” 측과 퀴놀론계 í•­ìƒ?ì œì?¸ '레사신정 (성분명 Levofloxacin)'ì?˜ ê³µë?™ íŒ?매 계약ì?„ 진행하는 등 BPH ë°? í•­ìƒ?ì œ 시장ì?˜ ì ?유 확대 ë¿? 아니ë?¼, ... 데일리팜

China's Jade Pharmaceutical begins manufacturing antibiotic levofloxac...  -  Jan 12, 2007
...'Jade Pharmaceuticals is producing levofloxacin at the Jiangxi Jade Biochemistry Ltd manufacturing facility in Jiangxi Province,' said AMDL CEO Gary Dreher. ... Forbes

Penetration of topically applied levofloxacin into eyes with thin...  -  Jul 6, 2005
Correspondence: NL Wang, Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, No.1 Dongjiaominxiang street, Dongcheng District, ... Nature.com

Levofloxacin works well for ear infections in kids  -  Jan 10, 2007
NEW YORK (Reuters Health) - The broad-spectrum antibiotic levofloxacin is highly effective against the bacteria that typically cause ear infections in ... Reuters

TB Drug Treatment Can Lead to Severe Pneumonia  -  Mar 24, 2008
Minimum inhibitory concentrations (MIC) for all isolates were measured, and levofloxacin resistance was defined as an MIC of 4mg/L or more. ... Washington Post

… TENTATIVE APPROVAL FROM US FDA TO MARKET LEVOFLOXACIN …  -  Apr 24, 2006
The branded sales of Levofloxacin Tablets in the US market in 2005 was estimated at USD$ 1.2 bn (NDC). The Company will market the drug through its US ... Pay-Per-View - Hindustan Times - Factiva, from Dow Jones

Levofloxacin-Based Triple Therapy in First-Line Treatment for …  -  Nov 14, 2005
Correspondence: Antonio Gasbarrini, Professor of Internal Medicine, Catholic University, Gemelli Hospital, Largo A Gemelli 8, 00168 Rome, Italy. ... Nature.com

Oculus Innovative's Microcyn meets primary endpoint in Phase II trial  -  Mar 14, 2008
...based biopharmaceutical company reported that Microcyn showed a 77.8% success rate compared with 61.1% for the levofloxacin plus saline treated patients. ... Forbes

AMDL Antibiotic Cleared in China  -  Nov 17, 2006
Drugmaker AMDL (ADL) announced that its China subsidiary Jade Pharmaceutical received approval from regulators there for its antibiotic levofloxacin. ... TheStreet.com - TheStreet.com (subscription)

Levofloxacin Prevents Infection in Neutropenic Cancer Patients  -  Sep 7, 2005
NEW YORK SEP 07, 2005 (Reuters Health) - Fears of bacterial resistance have generally prevented the prophylactic use of fluoroquinolones in patients with ... Cancerpage.com

Oculus reaches primary endpoint in Phase II trial of Microcyn for...  -  Feb 27, 2008
The study, which evaluated Microcyn as a monotherapy and in combination with systemic antibiotic levofloxacin after 10 days, demonstrated that 75% of ... Forbes

Levofloxacin IV : User Ratings covering uses, effectiveness, interacti...  -  Oct 12, 2007
I experienced an allergic reaction to this drug. Symptoms were an uncontrollable rigidness in my neck, chest and arms. Difficulty breathing, nervousness and ... WebMD

Levofloxacin Prevented Fever and Infection During Prolonged …  -  Mar 30, 2006
By Bucaneve, G; Micozzi, A; Menichetti, F; Tattersall, Martin. Bucaneve G, Micozzi A, Menichetti F, et al. Levofloxacin to prevent bacterial infection in ... RedOrbit

Losing an Old Friend: Goodbye to Ciprofloxacin?  -  Jul 11, 2008
...announced Thursday that it will require manufacturers of fluoroquinolone antibiotics — the group that includes ciprofloxacin and levofloxacin, ... ABC News

Levofloxacin-based triple therapy against persistent ulcer-inducing …  -  May 10, 2006
For those who suffer from stomach ulcers, the daily routine of breakfast, lunch and dinner can be painful. A common cause of these ulcers, as well as other ... News-Medical.net

Levofloxacin Treatment of Active Tuberculosis and the Risk of Adverse...  -  Sep 28, 2005
Background: Fluoroquinolones are commonly used in the treatment of tuberculosis (TB) for drug-sensitive patients who are intolerant to first-line ... RedOrbit

Levofloxacin treatment in patients with rheumatoid arthritis receiving...  -  Feb 1, 2007
Background: Sulfasalazine and tetracyclines are effective against rheumatoid arthritis (RA). Levofloxacin, the bacteriologically active isomer of ofloxacin, ... Free with registration - Southern Medical Journal - AccessMyLibrary.com

Teva Announces Tentative Approval of Levofloxacin Injection.  -  Feb 13, 2005
JERUSALEM -- Teva Pharmaceutical Industries Ltd. (Nasdaq: TEVA) announced today that the US Food and Drug Administration has granted tentative approval for ... Free with registration - Business Wire - AccessMyLibrary.com

… following concurrent amiodarone and levofloxacin therapy.(Clinical...  -  Oct 1, 2006
The third day after the operation, levofloxacin 250 mg intravenously daily was ... The dose of levofloxacin was increased to 500 mg daily due to a further ... Free with registration - Baylor University Medical Center... - AccessMyLibrary.com

Avelox As Effective As Levofloxacin Combination Therapy For Severe …  -  Apr 12, 2006
AVELOX (moxifloxacin HCl) monotherapy at 400 mg once daily is as effective as the high-dose combination of levofloxacin (500 mg twice daily) plus ... Medical News Today - Medical News Today (press release)

Levofloxacin Appears Safe and Effective for CAP in Children  -  Mar 15, 2008
Background: Levofloxacin (Levaquin) is not approved by the US Food and Drug Administration for use in children, but historical data on fluoroquinolones in ... AAFP News Now

… of Tigecycline Compared to Levofloxacin for Treating Streptococcus...  -  Apr 5, 2007
By Chris Berrie. MUNICH, GERMANY -- April 5, 2007 -- The first-in-class glycylcycline agent, tigecycline, appears safe and shows a clinical cure rate that ... DG News

Anti-Infectives; Levofloxacin prevents bacterial infection in...  -  Oct 27, 2005
2005 OCT 27 - (NewsRx.com) -- Prophylactic use of levofloxacin can prevent bacterial infection in patients with cancer and neutropenia. ... Pay-Per-View - Blood Weekly - Factiva, from Dow Jones

… with Cure Rates Similar to Levofloxacin in Hospitalized Patients...  -  Oct 4, 2006
By Paula Moyer. SAN FRANCISCO, CA -- October 4, 2006 -- Patients are hospitalized with community-acquired pneumonia have a cure rate of 89.7% when they are ... DG News

Once Daily Levofloxacin for 5 Days in the Treatment of Acute …  -  Apr 2, 2007
By Chris Berrie. MUNICH, GERMANY -- April 2, 2007 -- Five doses of levofloxacin are non-inferior to 20 doses of ciprofloxacin for the eradication of blood ... DG News

Once-Daily Oral Levofloxacin Effective and Safe in Patients With...  -  Apr 24, 2008
By Chris Berrie. BARCELONA, Spain -- April 24, 2008 -- Once-daily oral dosing of the fluoroquinolone levofloxacin is well tolerated and clinically and ... DG News

Levofloxacin looks effective for H. pylori.(Clinical Rounds) |...  -  Oct 1, 2005
Levofloxacin looks effective for H. pylori.(Clinical Rounds) ... find Family Practice News articles. Chicago -- Levofloxacin-based therapy is superior to ... Pay-Per-View - Family Practice News - HighBeam Research

Effect of ciprofloxacin and levofloxacin on the QT interval: is this...  -  Jan 1, 2006
Background: The widespread use of the fluoroquinolones has raised the question of the cardiac safety of these medications. This widespread use of this class ... Free with registration - Southern Medical Journal - AccessMyLibrary.com

Interaction between warfarin and levofloxacin: case series.(Case...  -  Jul 1, 2007
Interaction between warfarin and levofloxacin: case series.(Case Report) ... find Southern Medical Journal articles. Abstract: Warfarin is the most widely ... Pay-Per-View - Southern Medical Journal - HighBeam Research

Antimicrobial Agents; Levofloxacin may be an option for refractory H....  -  Feb 14, 2005
2005 FEB 14 - (NewsRx.com & NewsRx.net) -- A recent report describes high levels of dual resistance to clarithromycin and metronidazole and in vitro ... Pay-Per-View - Health & Medicine Week - Factiva, from Dow Jones

Researchers find improved treatment for pneumonia in elderly  -  Jan 24, 2006
The antibiotic moxifloxacin HCI has proved more effective in battling community-acquired pneumonia in patients 65 and older than levofloxacin, ... Bizjournals.com

Oral levofloxacin adequate for preventing ocular infections in study  -  Jun 21, 2007
Oral levofloxacin administered at doses of 400 mg/day provides adequate ocular penetration for preventing infections in the anterior chamber and vitreous of ... OSN SuperSite

Antimicrobial Agents; Levofloxacin may be an option for refractory H....  -  Feb 18, 2005
2005 FEB 18 - (NewsRx.com & NewsRx.net) -- A recent report describes high levels of dual resistance to clarithromycin and metronidazole and in vitro ... Pay-Per-View - Drug Week - Factiva, from Dow Jones

Tigecycline matches levofloxacin vs. pneumonia.(Infectious Diseases)(...  -  Jun 1, 2006
NICE, FRANCE -- Tigecycline is as effective as levofloxacin in treating patients hospitalized with community-acquired pneumonia, results of a phase III ... Free with registration - Internal Medicine News - AccessMyLibrary.com

Levofloxacin drop introduced for corneal ulcers  -  Nov 11, 2007
Levofloxacin ophthalmic solution 1.5% (Iquix) has been introduced for the treatment of corneal ulcers. It is the only newer-generation fluoroquinolone ... Ophthalmology Times

… /Loperamide Comparable With Levofloxacin/Loperamide for Treatment...  -  Oct 11, 2005
By Rabiya Tuma. SAN FRANCISCO, CA -- October 11, 2005 -- Azithromycin and loperamide works as well as, but is slower to take effect than levofloxacin and ... DG News

TaiGen Announces Presentation of Nemonoxacin at the Joint Meeting of ...  -  Oct 20, 2008
The top-rated phase 2 data of a randomized double-blind trial in comparison to levofloxacin will be reported. Nemonoxacin met the primary endpoints of ... International Business Times

… as Effective as High-Dose Levofloxacin and Ceftriaxone Combination...  -  Apr 7, 2006
KENILWORTH, NJ, April 7 /PRNewswire-FirstCall/ -- AVELOX(R) (moxifloxacin HCl) monotherapy at 400 mg once daily is as effective as the high-dose combination ... Free with registration - PR Newswire - AccessMyLibrary.com

Topical levofloxacin reduces ocular surface bacteria after 1 day  -  Oct 23, 2007
One-day and 3-day applications of topical levofloxacin show similar efficacy for reducing ocular surface bacteria, a study by researchers in California ... OSN SuperSite

BACTERIAL INFECTIONS .  -  Sep 19, 2005
Levofloxacin is in a class of antibiotics called fluoroquinolones and works by eliminating bacteria that cause infec tions. ... Milwaukee Journal Sentinel - Google News Archive

… /Shionogi's Avelox Has Advantages Over Levofloxacin in the Treatment...  -  Apr 17, 2008
Bayer/Schering-Plough/Shionogi's Avelox Has Advantages Over Levofloxacin in the Treatment of Community-Acquired Pneumonia. from PR Newswire. Pay-Per-View - PR Newswire - HighBeam Research

Levofloxacin safe, effective against pneumonia in children.(News)  -  Nov 1, 2007
Levofloxacin appears to be at least as safe and effective as standard-of-care drugs for children with community-acquired pneumonia, Dr. John S. Bradley and ... $4.95 - Pediatric News - ECNext

… 2006 - ABST [68] Lower level of levofloxacin induces biofilm...  -  May 21, 2006
Introduction and Objective: Bacterial biofilms are defined as surface-associated bacterial communities. One of the most striking features of bacteria in a ... UroToday International Journal

Levofloxacin Prophylaxis Beneficial Despite Antimicrobial Resistance  -  Apr 28, 2005
NEW YORK APR 28, 2005 (Reuters Health) - Levofloxacin prophylaxis for chemotherapy-related neutropenia may reduce morbidity and infection-related mortality, ... Cancerpage.com

Rib-X Pharmaceuticals Reports Positive Top-Line Results from Phase 2 ...  -  Dec 8, 2008
The second study compared delafloxacin to levofloxacin in the treatment of acute bacterial exacerbation of chronic bronchitis (ABECB). ... RedOrbit

Levofloxacin should be the first choice for antibacterial prophylaxis  -  Sep 12, 2006
Levofloxacin 0.5% eye drops should be the first choice for antibacterial prophylaxis and treatment, according to Professor P. Asbell of the Mount Sinai ... Ophthalmology Times

… tentative US OK for generic levofloxacin.(Pharmaceutical industry)(...  -  Feb 21, 2005
Teva notes that its levofloxacin injection is the AP-rated generic equivalent of Ortho McNeil's broad-spectrum antibacterial agent Levaquin Injection, ... $4.95 - Pharma Marketletter - ECNext

Oculus Innovative Sciences Announces Fiscal Second Quarter 2008 …  -  Aug 6, 2008
The trial is designed to show only that topical Microcyn has sufficiently similar cure and improvement rates to oral levofloxacin, thereby providing ... businesswire.com

Levofloxacin succeeds vs. AOM.(Clinical Capsules)(Drug overview)(Brief...  -  Jan 1, 2007
Treatment with oral levofloxacin is safe and effective against bacteria in the middle-ear fluid of children with recurrent or persistent acute otitis media, ... Free with registration - Pediatric News - AccessMyLibrary.com

Levofloxacin (Ophthalmic).(Drug overview)  -  Aug 1, 2006
Ophthalmic levofloxacin (lee-voh-FLOKS-a-sin) is used in the eye to treat bacterial infections of the eye . Ophthalmic levofloxacin works by killing ... Free with registration - USP DI-Volume II, Advice for the... - AccessMyLibrary.com

… ; Efficacy of culture media for levofloxacin susceptibility testing...  -  Feb 7, 2005
..."To determine the stability of levofloxacin in the two newer test systems (BACTEC ... "Results show that levofloxacin is stable over the course of testing," ... Pay-Per-View - Health & Medicine Week - Factiva, from Dow Jones

(Taiwan) TaiGen continues advancing its drug development pipeline  -  Apr 8, 2008
TaiGen announced that nemonoxacin had met the primary endpoint of non-inferiority versus levofloxacin, the leading quinolone on the market. ... Biotecheast.com

Five Days Of LEVAQUIN® (levofloxacin) As Effective As 10 Days Of …  -  May 29, 2007
Data presented today at a major medical meeting found that LEVAQUIN® (levofloxacin) 750 mg tablets administered once-daily for five days is as effective as ... Medical News Today - Medical News Today (press release)

… ; Adverse events similar between levofloxacin and conventional...  -  Dec 6, 2005
Marra concluded, "Concomitant use of a levofloxacin-containing regimen resulted in a ... Marra and colleagues published their study in Chest (Levofloxacin ... Pay-Per-View - Life Science Weekly - Factiva, from Dow Jones

AMDL Announces Launch Of Antibiotic Levofloxacin In China  -  Nov 18, 2006
AMDL (Amex: ADL) announced today that its China subsidiary, Jade Pharmaceutical Inc., has received approval from the China State Food and Drug ... Medical News Today - Medical News Today (press release)

… in bronchitis flare-up.(Infectious Diseases)(cethromycin; levofloxa...  -  Feb 1, 2007
Infectious Diseases)(cethromycin; levofloxacin)(Clinical report) ... find Internal Medicine News articles. SAN FRANCISCO -- Clinical signs and symptoms of ... Pay-Per-View - Internal Medicine News - HighBeam Research

… ; Efficacy of culture media for levofloxacin susceptibility testing...  -  Feb 11, 2005
..."To determine the stability of levofloxacin in the two newer test systems (BACTEC ... "Results show that levofloxacin is stable over the course of testing," ... Pay-Per-View - Drug Week - Factiva, from Dow Jones

… ; Efficacy of culture media for levofloxacin susceptibility testing...  -  Feb 13, 2005
..."To determine the stability of levofloxacin in the two newer test systems (BACTEC ... "Results show that levofloxacin is stable over the course of testing," ... Pay-Per-View - Medical Devices & Surgical Technology... - Factiva, from Dow Jones

China Sky One Medical (CSKI) Subsidiary Receives Production Approval ...  -  Dec 23, 2008
Levofloxacin Lactate injection is used to treat moderate to severe respiratory system, urinary system, and digestive system infections, as well as soft skin ... StreetInsider.com - StreetInsider.com (subscription)

Levofloxacin looks effective for H. pylori.(Clinical Rounds)  -  Oct 1, 2005
Chicago -- Levofloxacin-based therapy is superior to the other commonly used antibiotic combinations for Helicobacterpylori eradication, both as first- and ... Pay-Per-View - Family Practice News - Factiva, from Dow Jones

HITK Receives Tentative Approval for Levofloxacin Ophthalmic Solution  -  Mar 30, 2005
Hi-Tech Pharmacal Co., Inc. (NASDAQ: HITK) announced that the US Food and Drug Administration (FDA) has granted tentative approval to the Company's ... StreetInsider.com - StreetInsider.com (subscription)

Levofloxacin (Ophthalmic).  -  Feb 1, 2006
First, wash your hands. Then tilt the head back and pull the lower eyelid away from the eye to form a pouch. Drop the medicine into the pouch and gently ... Free with registration - USP DI-Volume II, Advice for the... - AccessMyLibrary.com

… in bronchitis flare-up.(Infectious Diseases)(cethromycin; levofloxa...  -  Feb 1, 2007
A new study comparing a 300-mg daily dose of cethromycin with levofloxacin therapy is warranted, said Dr. Eiznhamer of Advanced Life Sciences, ... $4.95 - Internal Medicine News - ECNext

Article: Effect of ciprofloxacin and levofloxacin on the QT interval:...  -  Jan 1, 2006
Effect of ciprofloxacin and levofloxacin on the QT interval: is this a significant "clinical" event?(Original Article) ... find Southern Medical Journal ... Pay-Per-View - Southern Medical Journal - HighBeam Research

Hi-Tech Pharmacal Receives Tentative Approval for Levofloxacin …  -  Mar 30, 2005
Hi-Tech's Levofloxacin Ophthalmic Solution USP, 0.5% is the generic equivalent of Santen's Quixin(R) Ophthalmic Solution, 0.5% indicated for the treatment ... Free with registration - Business Wire - AccessMyLibrary.com

Azithromycin Microspheres and Levofloxacin Equally Effective in COPD:...  -  May 22, 2006
By Jill Stein. SAN DIEGO, CA -- May 22, 2006 -- Single-dose azithromycin-microspheres (AZ-M) and 7-day levofloxacin (LEV) are equally effective treatments ... DG News

Generic 750 mg levofloxacin (Levaquin[R]) for bacterial infections in...  -  May 1, 2005
A first-time generic formulation of 750 mg levofloxacin tablets (Levaquin, ... Levofloxacin is a fluoroquinolone antibiotic and is currently indicated for ... Free with registration - Journal of Drugs in Dermatology - AccessMyLibrary.com

Zydus Cadila receives tentative approval for Levofloxacin  -  May 15, 2006
Zydus Cadila has received tentative approval from the USFDA to market Levofloxacin Tablets, 250 mg, 500 mg and 750 mg in the US market. ... Express Pharma

Drug Resistance; Ciprofloxacin, ofloxacin, and levofloxacin have...  -  Jan 2, 2006
2006 JAN 2 - (NewsRx.com) -- Ciprofloxacin, ofloxacin, and levofloxacin have potent in vitro activity against Mycobacterium tuberculosis. ... Pay-Per-View - Anti-Infectives Week - Factiva, from Dow Jones

Antimicrobial Agents; Levofloxacin may be an option for refractory H....  -  Feb 15, 2005
2005 FEB 15 - (NewsRx.com & NewsRx.net) -- A recent report describes high levels of dual resistance to clarithromycin and metronidazole and in vitro ... Pay-Per-View - Life Science Weekly - Factiva, from Dow Jones

Helicobacter Pylori; New levofloxacin cures MET- and CLA-susceptible...  -  Mar 28, 2006
..."Failed primary anti-H. pylori therapy results in a high rate of antimicrobial resistance. This necessitates a search for new regimens to cure H. pylori ... Pay-Per-View - Life Science Weekly - Factiva, from Dow Jones

Anti-Infectives; Levofloxacin prevents bacterial infection in...  -  Oct 24, 2005
2005 OCT 24 - (NewsRx.com) -- Prophylactic use of levofloxacin can prevent bacterial infection in patients with cancer and neutropenia. ... Pay-Per-View - Health & Medicine Week - Factiva, from Dow Jones

Levofloxacin treatment in patients with rheumatoid arthritis receiving...  -  Feb 1, 2007
Levofloxacin treatment in patients with rheumatoid arthritis receiving methotrexate.(Original Article)(Clinical report) ... find Southern Medical Journal ... Pay-Per-View - Southern Medical Journal - HighBeam Research

University Hospital of Marburg; New levofloxacin cures MET- and CLA- …  -  Mar 29, 2006
..."Failed primary anti-H. pylori therapy results in a high rate of antimicrobial resistance. This necessitates a search for new regimens to cure H. pylori ... Pay-Per-View - Biotech Week - Factiva, from Dow Jones

Levofloxacin safe, effective against pneumonia in children.(News) |...  -  Nov 1, 2007
Levofloxacin safe, effective against pneumonia in children.(News) ... find Pediatric News articles. Levofloxacin appears to be at least as safe and ... Pay-Per-View - Pediatric News - HighBeam Research

Chlamydia Pneumoniae; Levofloxacin does not eliminate C. pneumoniae …  -  Mar 1, 2005
..."Although antibiotics are known to affect the intracellular growth of Chlamydia pneumoniae in acute infections, their efficacy in therapy for chronic ... Pay-Per-View - Life Science Weekly - Factiva, from Dow Jones

… a new 5-day treatment regimen for levofloxacin (Levaquin, Ortho...  -  Sep 1, 2005
FDA approved a new 5-day treatment regimen for levofloxacin (Levaquin, Ortho-McNeil) for the treatment of acute bacterial sinusitis. Free with registration - Formulary - AccessMyLibrary.com

… Detects Decreasing Susceptibility to Levofloxacin and Macrolides...  -  Apr 2, 2007
However, macrolide susceptibility has predominantly decreased, and, of note, levofloxacin susceptibility has decreased, with the detection of resistant ... DG News

Chlamydia Pneumoniae; Levofloxacin does not eliminate C. pneumoniae …  -  Mar 6, 2005
..."Although antibiotics are known to affect the intracellular growth of Chlamydia pneumoniae in acute infections, their efficacy in therapy for chronic ... Pay-Per-View - Medical Devices & Surgical Technology... - Factiva, from Dow Jones

Chlamydia Pneumoniae; Levofloxacin does not eliminate C. pneumoniae …  -  Mar 2, 2005
..."Although antibiotics are known to affect the intracellular growth of Chlamydia pneumoniae in acute infections, their efficacy in therapy for chronic ... Pay-Per-View - Immunotherapy Weekly - Factiva, from Dow Jones

AMDL to produce levofloxacin in China.  -  Jan 15, 2007
AMDL to produce levofloxacin in China. California, USA-headquartered AMDL says that its Chinese subsidiary, Jade Pharmaceutical, has begun production of the ... $9.94 - Pharma Marketletter - Alacra Store

… Release: Teva granted approval for Levofloxacin Tablets and...  -  Jan 28, 2005
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New Treatment Against Persistent Ulcer-inducing Bacteria Successful  -  May 5, 2006
Levofloxacin is commonly prescribed to treat such infections as pneumonia, ... Levofloxacin-based triple therapy may offer an effective and safe treatment ... sciencedaily.com

… : AMDL Announces Launch of Antibiotic Levofloxacin in China. - PR …  -  Nov 17, 2006
AMDL Announces Launch of Antibiotic Levofloxacin in China. from PR Newswire. Highbeam Research – FREE Trial. Pay-Per-View - PR Newswire - HighBeam Research

Oculus fills up clinical trial for foot ulcer treatment  -  Dec 5, 2007
The company aims to show in the tests that its topical Microcyn treatment works as well as the oral treatment levofloxacin. Results of the test should be ... San Francisco Business Times

First-Time Generic Approvals: Climara, Duragesic, Levaquin  -  Feb 11, 2005
Levofloxacin is a fluoroquinolone antibiotic indicated in the treatment of various infections caused by susceptible gram-negative and gram-positive ... Medscape

Outpatient Treatment of Low-Risk Pneumonia Patients Effective, More …  -  Jan 31, 2005
The patients were randomized to either outpatient treatment with oral levofloxacin (500 mg/d), or hospitalization at one of two hospitals in Barcelona, ... MedPage Today

Enrollment Complete in Microcyn Trial  -  Dec 6, 2007
...which is being conducted at 15 US sites, is designed to demonstrate that topical Microcyn has similar cure and improvement rates as oral levofloxacin. ... FDA news - FDA news (subscription)

Article: Levofloxacin succeeds vs. AOM.(Clinical Capsules)(Drug …  -  Jan 1, 2007
Levofloxacin succeeds vs. AOM.(Clinical Capsules)(Drug overview)(Brief article) ... find Pediatric News articles. Treatment with oral levofloxacin is safe ... Pay-Per-View - Pediatric News - HighBeam Research

… as Effective as High-Dose Levofloxacin and Ceftriaxone Combination...  -  Apr 7, 2006
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IVAX Receives Tentative Approval for Levofloxacin Tablets.  -  May 19, 2005
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Fluoroquinolone prophylaxis in chemotherapy-induced neutropenia  -  Feb 25, 2008
Levofloxacin, a second generation fluoroquinolone, has been studied more recently ... Levofloxacin has better coverage for gram-positive organisms but it is ... HemOncToday

PRESS RELEASE: FDA Approves LEVAQUIN for Urinary Tract Infections …  -  Sep 17, 2007
Levofloxacin is not indicated for pediatric patients (<18 years of age). Levofloxacin is contraindicated in persons with known hypersensitivity to ... FierceBiotech

… Bits)(Food and drug administration)(Levaquin (levofloxacin) and...  -  Apr 1, 2005
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Generic Drugs; Tentative approval granted for Levofloxacin Ophthalmic...  -  Apr 29, 2005
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… Fluticasone approval granted in UK, tentative levofloxacin approval...  -  Jun 20, 2005
Levofloxacin tablets is the generic equivalent of Levaquin Tablets, a quinolone antibiotic used to treat lung, sinus, skin and urinary tract infections ... Pay-Per-View - Health & Medicine Week - Factiva, from Dow Jones

… Fluticasone approval granted in UK, tentative levofloxacin approval...  -  Jun 21, 2005
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Elusys' Anthrax Drug, Anthim(TM), Superior to Antibiotic as a Post- …  -  Feb 16, 2006
This study was designed to determine if the co-administration of Anthim and the antibiotic levofloxacin after exposure to a lethal, ... $4.95 - PR Newswire - ECNext

AMDL to Address Chinese Pharmaceutical Market With Recent Product …  -  Nov 28, 2006
The market for antibiotic products (including Roxithromycin and Levofloxacin) exceeded (US) $4.8 billion globally in 2003 with a continuing estimated growth ... Free with registration - PR Newswire - AccessMyLibrary.com

Hi-Tech Pharmacal Co., Inc. Tentative approval granted for Levofloxaci...  -  Apr 27, 2005
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Quinolone safety and efficacy.(LETTERS)(Letter to the Editor)  -  Jun 1, 2005
...(7) levofloxacin was studied in only 16 patients classified as having severe ... (8) a dose of levofloxacin 500 mg every 12 hours was studied in severe ... $4.95 - Emerging Infectious Diseases - ECNext

Brand Names/Synonyms:
Levofloxacin is also known by the following brand names and/or synonymsCravit; Cravit Ophthalmic; Elequine; Floxel; IQUIX; Leroxacin; Lesacin; Levaquin Leva-Pak; Levaquin; Levokacin; Levox; Levoxacin; Mosardal; Nofaxin; Quixin; Reskuin; Tavanic; Volequin

Drug Category:
Levofloxacin is categorized under the following by the FDA: Anti-bacterial Agents; Anti-Infectives; Quinolones; ATC:J01MA12; ATC:S01AX19

Dosage Forms:
TABLET, LIQUID, SOLUTION

Absorption:
Absorption of ofloxacin after single or multiple doses of 200to 400 mg is predictable, and the amount of drug absorbed increases proportionately with the dose.

Interactions:
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Chemical IUPAC Name:
(-)-(S)-9-fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7Hpyrido[1,2,3-de]-1,4 benzoxazine-6-carboxylic acid hemihydrate





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