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LevoletThis page contains recent news articles, when available, and an overview of Levolet but does not offer medical advice. You should contact your physician with regard to any health issues or concerns.Overview: Levolet (when available) Levothyroxine (T4) is a synthetically prepared levo isomer of thyroxine, a hormone secreted by the thyroid gland. Levothyroxine is used alone or in combination with antithyroid agents to treat hypothyroidism, goiter, chronic lymphocytic thyroiditis, myxedema coma, or stupor. For use as replacement or supplemental therapy in patients of any age or state (including pregnancy) with hypothyroidism of any etiology except transient hypothyroidism during the recovery phase of subacute thyroiditis or primary hypothyroidism resulting from thyroid dysfunction. Mechanism Of Action: Levothyroxine acts like the endogenous thyroid hormone thyroxine (T4, a tetra-iodinated tyrosine derivative). In the liver and kidney, T4 is converted to T3, an active metabolite. In order to increase solubility, the thyroid hormones attach to thyroid hormone binding proteins, thyroxin-binding globulin and thyroxin-binding prealbumin (transthyretin). Transport to thyroid hormone receptors in the cytoplasm and nucleus then takes place. News Articles on Levothyroxine Managing the challenges of hypothyroidism.(Disease/Disorder overview) - Jun 1, 2006 It also discusses management of hypothyroidism and use of thyroid hormone replacement therapy, particularly levothyroxine (synthetic T4) (Levo-T, Levolet, ... Free with registration - Journal of Family Practice - AccessMyLibrary.com Brand Names/Synonyms: Levolet is also known by the following brand names and/or synonymsD-Thyroxine; Eltroxin; Euthyrox; Iodine; L-T4; L-THYROXIN SODIUM, 99%; L-Thyroxine; L-Thyroxine Sodium; L-Thyroxine Sodium Salt; L-Thyroxine Sodium Salt Hydrate; L-Thyroxine.Na; Laevothyroxinum; Laevoxin; Letter; Levaxin; Levo-T; Levolet; Levothroid; Levothyrox; Levothyroxine; Levothyroxine Sodium; Levoxine; Levoxyl; Novothyrox; Oroxine; Sodium Levothyroxine; Synthroid; Synthroid Sodium; Tetraiodothyronine; Thyratabs; Thyrax; Thyreoideum; Thyro-Tabs; Thyro-Tapbs; Thyroxevan; Thyroxin; Thyroxinal; Thyroxine; Unithroid Drug Category: Levolet is categorized under the following by the FDA: Antithyroid Agents; Anticoagulants; ATC:H03AA01 Dosage Forms: LIQUID; POWDER; TABLET Absorption: Varies from 48% to 80% Interactions: [an error occurred while processing this directive] Chemical IUPAC Name: 2-amino-3-[4-(4-hydroxy-3,5-diiodo-phenoxy)-3,5-diiodo-phenyl]-propanoicacid |
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