Loniten

This page contains recent news articles, when available, and an overview of Loniten but does not offer medical advice. You should contact your physician with regard to any health issues or concerns.

Overview:

Loniten (when available)

Pharmacology and use:
Minoxidil is an orally effective direct acting peripheral vasodilator that reduces elevated systolic and diastolic blood pressure by decreasing peripheral vascular resistance. Minoxidil is also used topically to treat androgenetic alopecia. Microcirculatory blood flow in animals is enhanced or maintained in all systemic vascular beds. In man, forearm and renal vascular resistance decline; forearm blood flow increases while renal blood flow and glomerular filtration rate are preserved. The predominant site of minoxidil action is arterial. Venodilation does not occur with minoxidil; thus, postural hypotension is unusual with its administration. The antihypertensive activity of minoxidil is due to its sulphate metabolite, minoxidil sulfate. Indicated in the treatment of severe hypertension and in the topical treatment (regrowth) of androgenic alopecia in males and females and stabilisation of hair loss in patients with androgenic alopecia.

Mechanism Of Action:
Minoxidil is thought to promote the survival of human dermal papillary cells (DPCs) or hair cells by activating both extracellular signal-regulated kinase (ERK) and Akt and by preventing cell death by increasing the ratio of BCl^-2/Bax. Minoxidil may stimulate the growth of human hairs by prolonging anagen through these proliferative and anti-apoptotic effects on DPCs. Minoxidil, when used as a vasodilator, acts by opening adenosine triphosphate-sensitive potassium channels in vascular smooth muscle cells. This vasodilation may also improve the viability of hair cells or hair follicles.

News Articles on Minoxidil

Help for Hair Loss: Men's Hair Loss -- Treatments  -  Jul 1, 2005
For many years, minoxidil, in pill form (brand name Loniten), was widely used to treat high blood pressure. Just like finasteride, researchers discovered a ... WebMD

Pleurisy.  -  May 1, 2007
...bromocriptine (Parlodel), cyclophosphamide (Cytoxan), methotrexate, methysergide (Sansert; not available in the United States), minoxidil (Loniten), ... $4.95 - American Family Physician - ECNext

Losing Your Hair? Here's What to Do  -  Aug 6, 2008
Topical application of 2 or 5 percent Minoxidil (loniten) is available over the counter under the name Rogaine. The exact mechanism of this treatment is ... Islam Online - Islam Online

Nitroglycerin.(Drug overview)  -  Dec 1, 2005
Isordil, others), isosorbide mononitrate (Ismo, others), blood vessel dilators such as Loniten, and beta-blocker medications such as Tenormin. ... Free with registration - PDR Family Guide to Prescription Drugs - AccessMyLibrary.com

Nitroglycerin.(Drug overview)  -  Jan 22, 2007
Isordil, others), isosorbide mononitrate (Ismo, others), blood vessel dilators such as Loniten, and beta-blocker medications such as Tenormin. ... Free with registration - PDR Family Guide to Prescription Drugs - AccessMyLibrary.com

Washington Administrative Code - WAC 260-70-680 This section …  -  Mar 17, 2006
Mibefradil Posicor Mibolerone Midodrine Pro-Amiline Minoxidil Loniten Moexipril (metabolite moexiprilat) Uniretic Muscarine Namumetone Anthraxan, ... Pay-Per-View - Washington Administrative Code - Loislaw

Loislaw Federal District Court Opinions - PALOZIE v. DAVIS (SDIll....  -  Aug 24, 2005
He states that Defendants Lyle, Bakke, Castillo, Walsh, Barger, Mays, and Cross withheld the drugs Lasix and Xanax and instead gave him Tenormin, Loniten, ... Pay-Per-View - Loislaw Federal District Court Opinions - Loislaw

E. 高血壓治療�?�用藥物�?�?�  -  May 2, 2008
B. Minoxidil(Loniten) 副作用為多毛症, �?�外用増髮, 改善禿頭. C. Nitroprusside(Nipride) 造�?紅血素變性, 甲狀腺機能�?足, 使用時�?需�?�光 ... udn.com

禿頭脫髮救星──美國活髮寶  -  Oct 8, 2006
...營養的天然�?生乳液﹔以�?�沒有包括在內，隨使用者情�?而定的藥物﹕�?�邦藥物管�?� 局(FDA)批准的米諾地爾(Loniten)的頭髮�?生治療藥物，全天然�?�本片劑DHT阻斷素。 ... epochtimes.com

Management of hypertension in older persons.  -  Feb 1, 2005
...(22) Like central alpha agonists, the vasodilators hydralazine (Apresoline) and minoxidil (Loniten) cause sodium and water retention and reflex tachycardia, ... $4.95 - American Family Physician - ECNext

Management of hypertension in older persons.  -  Feb 1, 2005
...(22) Like central alpha agonists, the vasodilators hydralazine (Apresoline) and minoxidil (Loniten) cause sodium and water retention and reflex tachycardia, ... Pay-Per-View - American Family Physician - Factiva, from Dow Jones

Brand Names/Synonyms:
Loniten is also known by the following brand names and/or synonymsAlopexil; Alostil; Apo-Gain; CHEMBANK82; Gen-Minoxidil; HSDB 6538; KC-125; Loniten; Lonolox; M142; Minodyl; Minossidile; Minossidile [Italian]; Minoxidil; Minoxidil [Usan:Ban:Inn]; Minoxidilum [Inn-Latin]; Minoxigaine; Minoximen; Normoxidil; PDP; Pierminox; Prexidil; Regaine; Rogaine; Rogaine Extra Strength for Men; Rogaine for Men; Rogaine for Women; Theroxidil; Triclosan; Tricoxidil; Trocoxidil

Drug Category:
Loniten is categorized under the following by the FDA: Vasodilator Agents; Antihypertensive Agents; Skin and Mucous Membrane Agents (84:92.00); ATC:C02DC01; ATC:D11AX01

Dosage Forms:
LIQUID, TABLET

Absorption:
Minoxidil is at least 90% absorbed from the GI tract in experimental animals and man.

Interactions:
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Chemical IUPAC Name:
3-hydroxy-2-imino-6-(1-piperidyl)-3H-pyrimidin-4-amine

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