Lovastatin

This page contains recent news articles, when available, and an overview of Lovastatin but does not offer medical advice. You should contact your physician with regard to any health issues or concerns.


Overview:

Lovastatin
(when available)

Pharmacology and use:
Lovastatin, an antilipemic agent produced by fermentation of Aspergillus terreus, is the first of a class of lipid-lowering agents known as the HMG-CoA reductase inhibitors. Lovastatin is used to treat hypercholesterolemia, to slow coronary atherosclerosis, and to prevent myocardial infarction and stroke. Lovastatin, like simvastin and unlike pravastatin, is a prodrug, concentrating active drug in the liver during first-pass circulation. For management as an adjunct to diet to reduce elevated total-C, LDL-C, apo B, and TG levels in patients with primary hypercholesterolemia and mixed dyslipidemia; For primary prevention of coronary heart disease

Mechanism Of Action:
Lovastatin is a lactone that is readily hydrolyzed in vivo to the corresponding b-hydroxyacid, a potent inhibitor of HMG-CoA reductase, the enzyme that catalyzes the conversion of HMG-CoA to mevalonate. The conversion of HMG-CoA to mevalonate is an early step in the biosynthetic pathway for cholesterol.

News Articles on Lovastatin

The Taming of the Heart Attack  -  ‎Jan 1, 2010‎
The first one, lovastatin (Mevacor), didn't come on the market until 1987," Nissen recalled. "It wasn't a very good statin, but it was a lot better than ... MedPage Today

Eli Lilly Deal to Sell Livalo Not Without Risks  -  ‎Dec 28, 2009‎
...before approving a formulary change from one of the generically available statins (simvastatin, pravastatin, or lovastatin) to a branded-only statin. ... BNET

Med combo averts MI and stroke in some  -  ‎Dec 23, 2009‎
Clinical leaders implemented a medication bundle consisting of a statin (typically lovastatin 40 mg/day) and an ACE inhibitor (typically lisinopril 20 ... Cortlandt Forum

FDA Hands-Off On St. John's wort Cataract Connections (Part 3)  -  ‎Dec 14, 2009‎
Consumers were warned not to buy or eat three red yeast rice products sold on the Web, in August 2007, because the active pharmaceutical agent lovastatin, ... InjuryBoard.com (blog)

Consult specialist to tackle dysfunction problem  -  ‎Dec 14, 2009‎
My high blood pressure and cholesterol are normal with the following meds: Lisinopril 20 mg, Niaispan 1000 mg and Lovastatin 20 mg daily. ... Danbury News Times

Fereste-te de grepfrut cand iei pastile!  -  ‎Dec 11, 2009‎
De exemplu, medicamentul Lovastatin, care coboara colesterolul, nu poate fi luat cu grepfrut, insa poate fi inlocuit cu Fluvastatin. Ziare.com

Bệnh cao mỡ trong máu – phần 2  -  ‎Dec 24, 2009‎
...ngưá»?i ta hay dùng chúng tôi gá»?i chung là Statin thí dụ các loại thuốc có tên Lipitor, Crestor hay là những loại như Pravachol, Lovastatin, Simvastatin… ... Đài Á Châu Tự Do

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Researchers Reconstitute Enzyme That Synthesizes Cholesterol Drug Lovastatin  -  ‎Nov 9, 2009‎
The lovastatin-synthesizing enzyme is one of the most interesting but least understood of the polyketide synthases, which are found in filamentous fungi and ... Science Daily (press release)

Is Red Yeast Rice Effective in Lowering Lipid Levels?  -  ‎Nov 12, 2009‎
Plasma clearance of lovastatin versus Chinese red yeast rice in healthy volunteers. J Altern Complement Med. 2005;11:1031-1038. ... Medscape

Red Yeast Rice and Hyperlipidemia: How Strong Is the Evidence?  -  ‎Oct 28, 2009‎
The Air Force/Texas Coronary Atherosclerosis Prevention Study (AFCAPS/TexCAPS) examined treatment with lovastatin vs placebo among patients without a ... Medscape

How wonderful are 'wonder' drugs?  -  ‎Nov 6, 2009‎
Discovered: Lovastatin, the first of the statin drugs, was first used in 1987. Used: to reduce the amount of cholesterol in cells – forcing them to take ... Telegraph.co.uk

Former patient, surgeon leads cancer treatment center  -  ‎Oct 27, 2009‎
Cantrell, 46, applied for a patent in 2003, and thinks he may be close to getting it after an arduous process, for his combination of Lovastatin and ... Nashville Business Journal

Surgeon with cancer tested radical new treatment on himself—successfully  -  ‎Oct 21, 2009‎
Finding nothing, he made a guess that paid off – he treated himself with an untested combination of lovastatin and interferon, taking copious notes on its ... Mesothelioma News

Complete Reconstitution of a Highly Reducing Iterative Polyketide Synthase  -  ‎Oct 22, 2009‎
We report efficient expression of the lovastatin nonaketide synthase (LovB) from an engineered strain of Saccharomyces cerevisiae, as well as complete ... Science Magazine (subscription)

Bundled medication associated with reduced risk for CV hospitalization  -  ‎Nov 2, 2009‎
The bundled combination of 40-mg lovastatin and 20-mg lisinopril was associated with reduced risk for hospitalization for MI and stroke in patients with ... Cardiology Today

Statin drugs may lower deaths from flu: study  -  ‎Oct 29, 2009‎
Statin drugs include AstraZeneca's Crestor, known generically as rosuvastatin, Bristol-Myers Squibb Pravachol or pravastatin and Merck's Mevacor, or lovastatin. Reuters

Red yeast rice: A natural approach to high cholesterol  -  ‎Oct 26, 2009‎
...that's used in traditional Chinese medicine, contains monacolin K, the same ingredient as in the prescription cholesterol drug lovastatin (Mevacor). ... Chicago Tribune

US: “Health benefits and risks of grapefruit and grapefruit juiceâ€?  -  ‎Nov 12, 2009‎
...cyclosporine, ethinyl, estradiol, felodipine, lovastatin, nifedipine, nimodipine, saquinavir, simvastatin, tacrolimus, testosterone, triazolam. ... FreshPlaza

The Adult Treatment Panel-IIIwomen nike air force (  -  ‎Oct 20, 2009‎
The results achieved with the dietary portfolio were virtually identical to the results obtained with lovastatin. The control diet achieved a paltry 8% ... 中金在线

FDA Approves Labeling Update for REYATAZ® (atazanavir sulfate) Capsules to ...  -  ‎Nov 5, 2009‎
...ergonovine, methylergonovine, cisapride, St. John's wort (Hypericum perforatum)-containing products, lovastatin, simvastatin, pimozide, or indinavir. ... WELT ONLINE

Alnylam Presents New Pre-Clinical Data on RNAi Therapeutics at ...  -  ‎Nov 5, 2009‎
...hepatocyte-derived cells in a culture system and to have additive effects together with the action of lovastatin in upregulation of LDLR protein levels. ... WELT ONLINE

What Risks Are Associated With High-Dose Rosuvastatin?  -  ‎Oct 22, 2009‎
...about twice as potent as atorvastatin, 4 times as potent as simvastatin, and at least 8 times as potent as pravastatin and lovastatin. ... Medscape

Rx copay cards: There's an easier way  -  ‎Nov 3, 2009‎
There are reasons that your physician may want you on atorvastatin instead of pravastatin or lovastatin. Not all medications are created equal. ... ModernMedicine

Protecting patients during influenza season especially important this year  -  ‎Nov 2, 2009‎
A lovastatin/caffeine combination was recently studied in H5N1-, H3N2- and H1N1-infected BALB/c mice (Liu Z, et al. Eur J Pharmaceutical Sci. ... Cardiology Today

Open enrollment: Time for your own health care debate  -  ‎Oct 24, 2009‎
But it does have therapeutic equivalents -- simvastatin, lovastatin, pravastatin, according to health insurer AmeriHealth. Most insurance plans will have ... Hillsboro Argus - OregonLive.com

… of Prescription-to-OTC Switch of Lovastatin (HRG Publication #1719)  -  Jan 14, 2005
For the switch of any statin, in this case lovastatin, none of the conditions are met and it is virtually certain that more harm than benefit would accrue ... Public Citizen - Auto Safety & Consumer...

Common drug cures learning disability  -  Nov 7, 2005
Lovastatin actually reversed the over-production of Ras and repaired the ... Lovastatin and other statins lower the lipids and, without anchors, ... New Scientist

Chinese Red Yeast Rice May Prevent Heart Attack  -  Jun 13, 2008
The XZK capsules contained a combination of lovastatin, lovastatin ... The extract of red yeast rice contains lovastatin, a drug that has been proven to ... Washington Post

Lovastatin restores the function of endothelial progenitor cells...  -  Nov 9, 2008
The aim of the study was to investigate whether lovastatin restores the survival and function of endothelial progenitor cells (EPCs) damaged by oxLDL. ... Nature.com

Atlanta health, diet and fitness news | ajc.com  -  Aug 9, 2007
FDA testing revealed that the products contain lovastatin, the active ingredient in Mevacor, a prescription drug approved for treating high cholesterol, ... Atlanta Journal Constitution

Niacin and Lovastatin (Systemic ).  -  Feb 1, 2006
Niacin extended-release and Lovastatin NYE-a-sin and LOE-va-sta-tin combination medicine is used to help lower high cholesterol and fat levels in the blood. ... Free with registration - USP DI-Volume II, Advice for the... - AccessMyLibrary.com

Medicine / A CLOSER LOOK; Is this statin ready for a place over the …  -  Dec 17, 2007
Proponents for changing the status of lovastatin, including some physicians and Merck, have pointed to the 14 million Americans at moderate risk of heart ... Pay-Per-View - Los Angeles Times - ProQuest Archiver

Red yeast rice, fish oil fight high cholesterol  -  Jul 17, 2008
It contains a substance called monacolin-K that is nearly identical to the cholesterol-lowering drug lovastatin (Mevacor), as well as several other ... Reuters UK

Baldwin co. to recall supplements.  -  Aug 21, 2007
The label of the product, Cholestrix, claimed that the lovastatin, an active ingredient in certain prescription cholesterol drugs, provided "powerful ... Free with registration - Newsday - AccessMyLibrary.com

Mix of pills merits a review  -  Dec 12, 2005
My doctor recently put me on lovastatin because my cholesterol is 245. ... Because red yeast rice also contains lovastatin, it would be inadvisable to ... Los Angeles Times

Red yeast rice extract XZK cuts risk of dying after heart attack  -  Jun 10, 2008
They are less hard to believe when it is remembered that red yeast rice was the source of the first statin drug, lovastatin. So, in effect, the patients ... Times Online

Niacin and Lovastatin (Systemic ).(Drug overview)  -  May 1, 2006
Niacin extended-release and Lovastatin NYE-a-sin and LOE-va-sta-tin combination medicine is used to help lower high cholesterol and fat levels in the blood. ... Free with registration - USP DI-Volume II, Advice for the... - AccessMyLibrary.com

Red Yeast Rice, Lovastatin Warning  -  Aug 27, 2007
WASHINGTON—FDA (www.FDA.gov) is warning consumers not to buy or eat three red yeast rice products promoted and sold on Web sites, as they may contain an ... Natural Products Industry Insider

Lovastatin Prevents Cardiovascular Disease in Patients With Chronic …  -  Nov 7, 2008
By Maggie Schwarz. PHILADELPHIA -- November 7, 2008 -- In patients with chronic kidney disease (CKD), the use of statin drugs does not prevent loss of ... DG News

Consumer Reports: Prescription Best Buys  -  Dec 5, 2007
For example, if you have high cholesterol, ask about switching from top-selling Lipitor to a new generic called Lovastatin. Savings: $64 a month. ... ABC News

Drug Capsule .What You Should Know .Azithromycin .  -  Aug 28, 2006
...pharmacist it you're taking any prescription or products, particularly aluminum- and magnesium-containing antacids digoxin, live vaccines, lovastatin. Milwaukee Journal Sentinel - Google News Archive

FDA rejects over-the-counter statin Mevacor  -  Jan 25, 2008
The FDA indicated that a 20 milligram dose of Mevacor OTC, or lovastatin, would require a revised label and additional data to obtain approval. ... msnbc.com

Cholesterol drug also helps memory  -  Nov 9, 2005
Lovastatin belongs to a family of drugs called statins, the most common ... The medicine, lovastatin, has a long record in lowering cholesterol. ... Pay-Per-View - Newsday - ProQuest Archiver

AMA Asks FDA to Reject Over-The-Counter Status for Lovastatin ( …  -  Dec 11, 2007
It said people who don't need statin therapy might buy lovastatin over-the-counter nonetheless, putting them at risk for such side effects as muscle pain, ... MedPage Today

Lovastatin Not Harmful to Patients With Liver Disease: Presented at...  -  May 25, 2006
By Bruce Sylvester. LOS ANGELES, CA -- May 25, 2006 -- Lovastatin use does not appear to be harmful to patients with pre-existing liver disease, ... DG News

Cholesterol buster  -  Aug 19, 2008
The extract also contains lovastatin, one of the original drugs proven to improve cholesterol profiles and decrease the risk of heart attack, ... Malaysia Star

Over-the-counter statins and cardiovascular disease prevention: …  -  May 17, 2005
Lovastatin was begun at 20 mg/d and was then titrated at week 18 to 40 mg/d if ... In the lovastatin group, 50% of the patients underwent titration for this ... Nature.com

… Cell Research; Fluvastatin and lovastatin induce neuroglial...  -  Feb 16, 2005
2005 FEB 16 - (NewsRx.com & NewsRx.net) -- Fluvastatin and lovastatin induce neuroglial differentiation in mesenchymal stem cells. ... Pay-Per-View - Immunotherapy Weekly - Factiva, from Dow Jones

Updates on heart health: the Portfolio diet challenges current...  -  Apr 1, 2006
The reductions in C-reactive protein were 10.0% for the control group, 33.3% for the Lovastatin group, and 28.2% for the Portfolio dieters. ... Free with registration - Prepared Foods - AccessMyLibrary.com

SoCal man pleads no contest to giving dog poisoned meatballs  -  Aug 23, 2007
30 after a toxicology report showed traces of rat poison, aspirin and lovastatin, a medication used to lower bad cholesterol, in the food. San Diego Union - Tribune - San Diego Union Tribune

Study: Red Rice Yeast Helps Cut Bad Cholesterol : NPR  -  Jul 1, 2008
One product had over 10 milligrams of lovastatin per pill; another one had less than 0.1 milligrams of lovastain. AUDREY: Another finding is that four of ... NPR

Atherogenesis; Lovastatin and fenofibrate have anti-inflammatory...  -  Jan 2, 2005
2005 JAN 2 - (NewsRx.com & NewsRx.net) -- Researchers have investigated C-reactive protein-induced expression of CD40-CD40L and the effect of lovastatin and ... Pay-Per-View - Heart Disease Weekly - Factiva, from Dow Jones

PEOPLE'S PHARMACY  -  Mar 23, 2007
My pharmacist says I must not eat grapefruit while I am taking lovastatin (a generic for Mevacor). Would it be safe if I eat my grapefruit at breakfast and ... Pay-Per-View - The Sun - ProQuest Archiver

Adding Niacin to Lovastatin Therapy Might Improve Efficacy for …  -  Oct 5, 2005
By Crystal Phend. SAN FRANCISCO, CA -- October 5, 2005 -- Adding extended release niacin to lovastatin appears to improve lipoprotein control in patients ... DG News

… panel rejects OTC switch for lovastatin.(Cardiovascular Medicine)(o...  -  Jan 15, 2008
FDA panel rejects OTC switch for lovastatin.(Cardiovascular Medicine)(over the counter drugs) ... find Internal Medicine News articles. SILVER SPRING, MD. Pay-Per-View - Internal Medicine News - HighBeam Research

Clinical Trials; Safety for heart patients taking lovastatin and...  -  Jun 27, 2006
2006 JUN 27 - (NewsRx.com) -- Moderate drinking did not adversely influence the safety of low-dose warfarin or even high-dose lovastatin among men with ... Pay-Per-View - Life Science Weekly - Factiva, from Dow Jones

Relief for dry hands  -  Mar 20, 2007
My pharmacist says I must not eat grapefruit while I am taking lovastatin (a generic for Mevacor). Would it be safe if I eat my grapefruit at breakfast and ... $2.95 - Buffalo News - NewsBank

Statins Stop Hepatitis C Virus From Replicating  -  Jul 6, 2006
Based on recent reports that one statin, lovastatin, inhibits HCV ... Atorvastatin and simvastatin had moderate effects while lovastatin had a weak effect. ... EndoNurse

FDA Advisers Again Oppose Over-the-Counter Sale of Lovastatin ( …  -  Dec 14, 2007
If lovastatin were available on drug store shelves, "there is going to be abuse," she said. Edwin L. Hemwall, of Merck Research Laboratories, ... MedPage Today

Fresh onion juice eases kitchen burns, prevents blisters  -  Jul 24, 2008
But I heard that in 2007, the Food and Drug Administration restricted sales of red yeast rice if it contained lovastatin, the ingredient in Mevacor. ... Youngstown Vindicator

With Warfarin .  -  Dec 7, 2005
My doctor recently put me on lovastatin cause my cholesterol is 1 have read ... Because red yeast rice also contains lovastatin, it would be inadvisable to ... Lakeland Ledger - Google News Archive

Smart Care via a Mouse, but What Will It Cost?  -  Aug 20, 2006
In recent years, Kaiser and the VA have been using generic lovastatin for many ... Kaiser's research on safety and effectiveness concluded that lovastatin ... New York Times

Ease up on meds to help muscle weakness  -  Apr 2, 2007
...a ago nu doctor changed me to lovastatin. For months. I complained to my doctor of severe cramps, and in both legs and hands I could hardly walk and ... Spokesman-Review - Google News Archive

Panel rejects OTC version of statin.(News)  -  Feb 15, 2005
Merck, which manufacturers lovastatin under the trade name Mevacor, has proposed that the daily 20-mg dose--at a retail price of about $1 per pill--be ... Pay-Per-View - OB GYN News - Factiva, from Dow Jones

Statin-free supplement? Not quite -- latimes.com  -  Jan 14, 2008
The industrious fungi growing on rice are actually little pharmaceutical factories creating a natural supply of monacolin K, also known as lovastatin. ... Los Angeles Times

Not all yeasts are the same  -  Jan 25, 2006
You can read more about red yeast rice and mevinolin (lovastatin) at www.nlm.nih.gov/medlineplus/druginfo/natural/patient-redyeast.html. ... Waterloo Cedar Falls Courier

… Cell Research; Fluvastatin and lovastatin induce neuroglial...  -  Feb 14, 2005
2005 FEB 14 - (NewsRx.com & NewsRx.net) -- Fluvastatin and lovastatin induce neuroglial differentiation in mesenchymal stem cells. ... Pay-Per-View - Cardiovascular Week - Factiva, from Dow Jones

… US OTC Marketing Rights to MEVACOR(R) (lovastatin) from Merck &...  -  Nov 26, 2007
MEVACOR* (Lovastatin) is a cholesterol lowering agent isolated from a strain of ... After oral ingestion, lovastatin, which is an inactive lactone, ... $4.95 - PR Newswire - ECNext

Lovastatin inhibits formation of AA amyloid  -  Feb 19, 2008
JCH van der Hilst * ,1 , B. Kluve-Beckerman , EJ Bodar * , JWM van der Meer * , JPH Drenth and A. Simon * ,. 1 Correspondence: Department of General ... Journal of Leukocyte Biology (subscripti...

… Cell Research; Fluvastatin and lovastatin induce neuroglial...  -  Feb 20, 2005
2005 FEB 20 - (NewsRx.com & NewsRx.net) -- Fluvastatin and lovastatin induce neuroglial differentiation in mesenchymal stem cells. ... Pay-Per-View - Medical Devices & Surgical Technology... - Factiva, from Dow Jones

Lovastatin and Gemfibrozol  -  Jun 12, 2007
My husband had high triglycerides and elevated cholestorol several years ago, and had been taking both Lovastatin and Gemfibrozol for all this time. ... HealthCentral.com

New research shows neuroprotective effect of lovastatin  -  Apr 9, 2008
April 9, 2008 High cholesterol levels are considered to be a risk factor for cardiovascular disease including stroke. Therefore, many cholesterol lowering ... Genetic Engineering News - Genetic Engineering News (press release)

FDA panels vote against lovastatin's OTC switch; several panel...  -  Feb 15, 2005
They also agreed that the 20-mg lovastatin dose was safe to use in the nonprescription setting without monitoring liver function, and, except for one member ... Pay-Per-View - Family Practice News - HighBeam Research

FDA Warns Consumers To Avoid Red Yeast Rice Products Promoted On …  -  Aug 12, 2007
FDA testing revealed the products contain lovastatin, the active ... This risk is greater in patients who take higher doses of lovastatin or who take ... Medical News Today - Medical News Today (press release)

Switches are now harder to come by.  -  Jan 2, 2006
A high-profile example in 2005 involved 20-mg lovastatin, a cholesterol-lowering agent. In January 2005 an FDA panel voted against recommending the ... $9.94 - Chain Drug Review - Alacra Store

Cholesterol Lowering: Neuroprotective Effect Of Lovastatin Described  -  Apr 12, 2008
ScienceDaily (Apr. 12, 2008) — High cholesterol levels are considered to be a risk factor for cardiovascular disease including stroke. ... sciencedaily.com

… secondary prevention trials with lovastatin, pravastatin, and...  -  Sep 12, 2005
Although six statins are currently available, large clinical trials reported thus far have mainly evaluated atorvastatin, lovastatin, pravastatin, ... OnMedica

Statins help kill brain cancer cells  -  Jan 22, 2007
The treatment, combining cholesterol-lowering statin drug lovastatin with ... In combination with lovastatin, the two drugs provide a powerful brake on the ... Cancer Research UK - News & Resources

Lovastatin inhibits formation of AA amyloid  -  Jan 3, 2008
JCH van der Hilst * @ , B. Kluve-Beckerman , EJ Bodar * , JWM van der Meer * , JPH Drenth , and A. Simon *. @ To whom correspondence should be addressed. ... Journal of Leukocyte Biology (subscripti...

… Not Approvable Letter from FDA for OTC MEVACOR® (lovastatin) 20 mg  -  Jan 28, 2008
...the US Food and Drug Administration (FDA) to its New Drug Application (NDA) seeking approval for over-the-counter (OTC) MEVACOR® (lovastatin) 20 mg. ... webwire.com

FDA Warns Consumers to Avoid Red Yeast Rice Products Promoted on …  -  Aug 14, 2007
FDA testing revealed the products contain lovastatin, the active ... This risk is greater in patients who take higher doses of lovastatin or who take ... webwire.com

HIV/AIDS Therapy; Lovastatin potentiates antitumor effects of...  -  Feb 28, 2005
..."Antiretroviral protease inhibitors have been shown to cause hyperlipidemia, raising concerns for the possibility of cardiovascular complications among ... Pay-Per-View - Cardiovascular Week - Factiva, from Dow Jones

New research shows neuroprotective effect of lovastatin  -  Oct 4, 2008
High cholesterol levels are considered to be a risk factor for cardiovascular disease including stroke. Therefore, many cholesterol lowering drugs have been ... innovations report - Innovations-Report

Medication May Reduce Alzheimer's and Parkinson's | Psych Central …  -  Jul 19, 2007
Using three different models for analysis, the researchers examined the effects of three different statins (atorvastatin, lovastatin and simvastatin) and ... PsychCentral.com

… and dissolution properties of lovastatin hydroxypropyl-[beta]...  -  Feb 1, 2007
Keywords: lovastatin, hydroxypropyl-[beta]-cyclodextrin, ... Lovastatin (LVS) is a well-known compound for lowering plasma cholesterol levels. ... $9.94 - Pharmaceutical Technology - Alacra Store

Article: FDA panels vote against lovastatin going OTC: fears were …  -  Feb 15, 2005
FDA panels vote against lovastatin going OTC: fears were expressed that the OTC version might be used by consumers with contraindicated conditions. ... find ... Pay-Per-View - Internal Medicine News - HighBeam Research

Article: FDA panel recommends against OTC lovastatin.(News)(Food and ...  -  Jan 1, 2008
FDA panel recommends against OTC lovastatin.(News)(Food and Drug Administration)(over the counter) ... find Family Practice News articles. Pay-Per-View - Family Practice News - HighBeam Research

Bentley Announces Product Approvals in Spain and Ireland.  -  Oct 29, 2007
Lovastatin is marketed in the United States by Merck & Co. under the trade ... The annual market size in Spain for lovastatin is approximately $14 million ... Free with registration - Business Wire - AccessMyLibrary.com

HIV/AIDS Therapy; Lovastatin potentiates antitumor effects of...  -  Mar 3, 2005
..."Antiretroviral protease inhibitors have been shown to cause hyperlipidemia, raising concerns for the possibility of cardiovascular complications among ... Pay-Per-View - Blood Weekly - Factiva, from Dow Jones

Is Medicare for everyone?  -  Dec 8, 2005
Following such a diet lowered most people's cholesterol about as much as the drug lovastatin current Atherosclerosis Reports, November 2004 In another ... Tuscaloosa News - Google News Archive

US considers establishing behind-the-counter drugs  -  Jan 29, 2008
13, 2007, when Merck requested over-the-counter status for a 20 mg dose of lovastatin (Mevacor). Merck's request was rejected by a vote of 10 to 2, ... CMAJ

Lovastatin in treating patients at high risk of recurrent melanoma.(SK...  -  Nov 1, 2007
Sponsors and Collaborators: Chao Family Comprehensive Cancer Center and National Cancer Institute (NCI). This randomized phase II trial is studying ... $4.95 - Journal of Drugs in Dermatology - ECNext

Jaw Side Effect From Fosamax Unusual  -  Sep 5, 2007
...wants me to take two cholesterol pills instead of the one pill that I usually take lovastatin 10 milligrams). Are two pills going to damage my liver more? ... Southeast Missourian - Google News Archive

Is Cranberry Sauce Safe With Blood Thinner?  -  Dec 5, 2005
Q. My doctor recently put me on lovastatin because my cholesterol is 245. ... A. Because red yeast rice also contains lovastatin, it would be inadvisable to ... HealthCentral.com

USA pharma: Lovastatin regimen shrinks patient tumor 70%  -  Dec 1, 2008
NeoPlas Innovation, a cancer treatment center in Nashville, Tennessee, USA, says that a new cancer therapy regimen using approved drugs is realizing ... $34.00 - EIU Country Analysis - Alacra Store

Lovastatin; Lovastatin attenuates CD40-mediated inhibition of Abeta …  -  Jan 2, 2005
..."These results provide an insight into the mechanism of the beneficial effects of lovastatin in neurodegenerative disorders, particularly Alzheimer's ... Pay-Per-View - Heart Disease Weekly - Factiva, from Dow Jones

More In Business Briefs  -  Oct 30, 2007
Merck said it has been advised that the NDA for OTC Mevacor (lovastatin) will be ... Merck is seeking approval of lovastatin 20 mg taken once daily to help ... Medical Marketing & Media - Medical Marketing and Media

06/18/07 #3 - Joint pain and triptans?  -  Jun 18, 2007
When I first went back to Imitrex all was fine but I am now getting some knee pain after taking Imitrex and I'm still on Lovastatin. Have you ever heard of ... HealthCentral.com

Competitors by Product Report  -  Jul 19, 2008
Eon Labs Lovastatin; Lescol (Fluvastatin Sodium); Lescol XL (Fluvastatin Sodium) ... IVAX Simvastatin; Lovastatin; Pravastatin Sodium; Simvastatin ... $75.00 - Revere Reports - Revere

Statins can cause loss of memory .  -  Mar 7, 2007
I started on lovastatin in September 2004. About January of 2005 1 began to have memory problems and a strange intermittent tremor of my lips (the upper lip ... Rock Hill Herald - Google News Archive

FDA Warns on Red Yeast Rice  -  Mar 7, 2008
Lovastatin is a type of cholesterol-lowering drug known as a statin that is also ... The FDA is concerned about these specific lovastatin-containing ... Newsinferno.com

News in brief - Jan. 14, 2008  -  Jan 14, 2008
13, 2007, against the nonprescription sale of lovastatin, which was approved in 1987 as the first of the blockbuster statin class of cholesterol-lowering ... American Medical News

A commonly prescribed drug reverses learning and attention deficits...  -  Nov 3, 2005
The work reported by Silva and colleagues this week in Current Biology demonstrates that a commonly prescribed statin drug, Lovastatin, can reverse the ... PsychCentral.com

FDA Moves to Shut Down Red Yeast Rice Distributors Online  -  Sep 20, 2007
The letter states, "FDA testing revealed the products contain lovastatin, ... Here is one case Fallon and Enig relate concerning Mevacor (lovastatin); ... Natural News.com

Drug reactions create a medical mess  -  Jan 28, 2007
Such medications included acetaminophen, thyroid hormone, sulfa, anti-inflammatory medications, digoxin and lovastatin/simvastatin. ... $3.50 - Intelligencer, The - NewsBank

Contamination Is A Common Problem in Red Yeast Rice Products  -  Jul 11, 2008
Red yeast rice is produced by fermenting yeast with rice, with the resultant product containing lovastatin, the active ingredient in the prescription drug ... Newsinferno.com

Effective Mesothelioma Treatment Found Using Cholesterol Drug - …  -  Aug 27, 2008
The drug under investigation is Lovastatin, which was introduced in 1980. Early studies on Lovastatin originally excited researchers because of the ... Asbestos.com

Eat Right to Reduce Heart Disease Risk  -  Mar 10, 2005
Lovastatin and the functional foods diet were equally able to reduce LDL ... There was no difference in heart disease risk between the lovastatin and ... Medfinds

Contamination common in red yeast rice products  -  Jul 9, 2008
Red yeast rice is produced by fermenting yeast with rice, and contains lovastatin, the active ingredient in the prescription drug Mevacor, a member of the ... Reuters

Competitors by Product Report  -  Jul 19, 2008
Eon Labs Lovastatin; Lescol (Fluvastatin Sodium); Lescol XL (Fluvastatin Sodium) ... IVAX Simvastatin; Lovastatin; Pravastatin Sodium; Simvastatin ... $75.00 - Revere - Alacra Store

Pour mieux combattre le cholestérol  -  Mar 8, 2006
...de LDL a atteint plus de 20 %, un résultat équivalent à un groupe étudié auparavant et qui était traité au médicament Lovastatin, précise-t-il. ... Le Devoir - Le Devoir (Abonnement)

Which Statin Is Right for My Patient?  -  Aug 28, 2007
Lovastatin, pravastatin, and simvastatin are derived from fungi, ... Lovastatin and simvastatin are prodrugs and must be hydrolyzed to the active hydroxy ... Medscape

FDA Safety Labeling Changes: Hectorol, Mevacor, Pulmicort Respules  -  Sep 28, 2005
On June 13, the FDA approved safety labeling revisions for lovastatin (Mevacor ... As with other HMG-CoA reductase inhibitors, lovastatin may cause myopathy ... Medscape

Generics aren't always cheaper.(LETTERS)(Letter to the Editor)  -  Dec 15, 2005
In the drug update on statins, you listed the cost of generic lovastatin as $6.40 per day, ... The cost information for generic lovastatin is correct. ... Free with registration - Internal Medicine News - AccessMyLibrary.com

é™?血脂藥勿與紅麴製劑並用  -  Jul 26, 2008
...國內共發出四å??å…­å¼µå?«æœ‰lovastatinæˆ?分的é™?血脂藥物藥證,扣除已註銷,大約還有近四 å??張,一顆約二å??毫克的lovastatinæˆ?分製劑,價格約在å??到å??五元之間。 ... 自由時報

statiné™?血脂藥加紅麴膠囊傷è‚?è…Ž  -  Jul 25, 2008
...但是紅麴膠囊是經�純化的產物,這些紅麴製�之所以有效,就來自於其中的Lovastatin�分。 黃瑞�說,Lovastatin�分跟醫師開立的statin類藥物,作用是�疊的,也就是說 ... ��新�網

TradeName : Aztatin, Elstatin, Favolip, Lestric, Lipistat, Lochol,...  -  Feb 21, 2007
Why it is prescribed (Indications) : Lovastatin is used, along with diet changes ie, ... When it is to be taken : Lovastatin usually is taken once a day ... MedIndia

Rhode Island news | projo.com | The Providence Journal  -  Jan 3, 2006
As an example, he points to lovastatin, a cholesterol-lowering drug ... Lovastatin costs $32 to $63 for a 30-day supply, and often does the job for patients ... Providence Journal

å?°ç?£ç™Œç—‡åŸºé‡‘會與å?°åŒ—醫大研究發ç?¾ï¼šé‡Žç”Ÿç´…樟èŠ?抑癌見療效  -  Mar 7, 2008
...賴基銘則指出,臨床上把Lovastatin併用樟�,�癌細胞明顯減少。�外,由�北醫學大學 研究團隊發表的「進�攻,退�守—兼具癌症�防與治療的牛樟��論文指出,H441GL ... 自由時報

The Grapefruit-Drug Interaction debate: role of statins.  -  Jul 15, 2007
The cited studies also used high-dose statins (80 mg of lovastatin, ... Grapefruit juice greatly increases serum concentrations of lovastatin and lovastatin ... Free with registration - American Family Physician - AccessMyLibrary.com

Press Release: NHLBI Study Will Examine Benefits of Raising HDL-C and...  -  Jul 6, 2005
A decision-analytic model found lovastatin/extended-release niacin to be superior to simvastatin ... than lovastatin/extended- release niacin ($665 versus ... Pay-Per-View - PR Newswire - HighBeam Research

FDA Advisers Reject Over-the-Counter Statin  -  Dec 14, 2007
Mevacor Daily [lovastatin 20 mg] is an appropriate choice for an OTC statin. The efficacy and safety of lovastatin has been well-established through the 20 ... Washington Post

PMS-Lovastatin – Emplois, Effets secondaires, Interactions - …  -  Jul 12, 2005
Prenez votre santé en main avec notre bulletin d'information. Demeurez informé et en bonne santé! Nous recherchons des gens souffrant de pression artérielle ... Canoë

… Approval of Merck's NDA for Non-prescription MEVACOR(R) (lovastatin...  -  Dec 13, 2007
After oral ingestion, lovastatin, which is an inactive lactone, ... The empirical formula of lovastatin is C24H36O5 and its molecular weight is 404.55. ... Free with registration - Business Wire - AccessMyLibrary.com

… Approval of Merck's NDA for Non-prescription MEVACOR(R) (lovastatin...  -  Dec 13, 2007
After oral ingestion, lovastatin, which is an inactive lactone, ... The empirical formula of lovastatin is C24H36O5 and its molecular weight is 404.55. ... $4.95 - Business Wire - ECNext

Brand Names/Synonyms:
Lovastatin is also known by the following brand names and/or synonymsCCRIS 7557; Compactin; Elisor; Lipostat; Lovastatin; Mevalotin; Mevastatin; Mevinolin; Oliprevin; Pravachol; Pravaselect; Pravastatin; Pravastatin Sodium; Pravastatina [Spanish]; Pravastatine [French]; Pravastatinum [Latin]; Selectin; Selipran; Vasten

Drug Category:
Lovastatin is categorized under the following by the FDA: Anticholesteremic Agents; HMG-CoA Reductase Inhibitors; ATC:C10AA03

Dosage Forms:
TABLET

Absorption:
Average oral absorption of pravastatin is 34% and absolute bioavailability is 17%.

Interactions:
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Chemical IUPAC Name:
3,5-dihydroxy-7-[6-hydroxy-2-methyl-8-(2-methylbutanoyloxy)-1,2,6,7,8,8a-hexahydronaphthalen-1-yl]-heptanoicacid





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