Maxzide

This page contains recent news articles, when available, and an overview of Maxzide but does not offer medical advice. You should contact your physician with regard to any health issues or concerns.

Overview:

Maxzide (when available)

Pharmacology and use:
Triamterene, a relatively weak, potassium-sparing distal tubule diuretic and antihypertensive, is used in the management of hypokalemia. Triamterene is similar in action to amiloride but, unlike amiloride, increases the urinary excretion of magnesium. For the treatment of oedema in congestive cardiac failure and renal and hepatic disease used with or without other diuretics to preserve potassium.

Mechanism Of Action:
Triamterene interferes with sodium reabsorption in the distal renal tubule by inhibiting sodium transport mechanisms directly. Specifically it inhibits the Na+/K+/2Cl^- co-transporter. The result is an electrical-potential difference across the membrane that blocks the passive distal tubular secretion of potassium. Relative to other diuretics, Triamterene has a unique mode of action as it inhibits the reabsorption of sodium ions in exchange for potassium and hydrogen ions at that segment of the distal tubule under the control of adrenal mineralocorticoids (especially aldosterone).

News Articles on Triamterene

What Is Vertigo? What Causes Vertigo?  -  ‎Aug 18, 2009‎
Diuretic medication, such as the drug combination triamterene and hydrochlorothiazide (Dyazide, Maxzide) may reduce fluid retention which lowers pressure in Medical News Today

Vitamin B6 can ease symptoms of nerve pain  -  Sep 13, 2008
Other medications on the drug mugger list for vitamin B6 include HCTZ, Vaseretic, Dyazide, Maxzide, Evista, hormone replacement drugs containing estradiol Tulsa World,

Just words, but Mrs. Clinton’s fell flat  -  Mar 2, 2008
...been taken in a field that includes such familiar products as Xanax, Zantac, Zocor, Zoloft, Prozac, Maxzide, Zithromax, Thorazine, Quinidine and Tylox. Worcester Telegram,

Brand Names/Synonyms:
Maxzide is also known by the following brand names and/or synonyms:
Ademin; Ademine; Diren; Ditak; Diucelpin; Diurene; Dyazide; Dyren; Dyrenium; Dytac; Jatropur; Maxzide; Maxzide-25; Noridil; Noridyl; Pterofen; Pterophene; SK&F 8542; SKF 8542; Taturil; Teriam; Teridin; Tri-Span; Triampur; Triamteren; Triamterene; Triamteril; Triamteril Complex; Trispan; Triteren; Urocaudal

Drug Category:
Maxzide is categorized under the following by the FDA: Diuretics; Potassium-sparing Diuretics; ATC:C03DB02

Dosage Forms:
TABLET

Absorption:
Triamterene is rapidly absorbed, with somewhat less than 50% of the oral dose reaching the urine.

Interactions:
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Chemical IUPAC Name:
6-phenylpteridine-2,4,7-triamine

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