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MequitazineThis page contains recent news articles, when available, and an overview of Mequitazine but does not offer medical advice. You should contact your physician with regard to any health issues or concerns.Overview: Mequitazine (when available) In allergic reactions an allergen interacts with and cross-links surface IgE antibodies on mast cells and basophils. Once the mast cell-antibody-antigen complex is formed, a complex series of events occurs that eventually leads to cell-degranulation and the release of histamine (and other chemical mediators) from the mast cell or basophil. Once released, histamine can react with local or widespread tissues through histamine receptors. Histamine, acting on H1-receptors, produces pruritis, vasodilatation, hypotension, flushing, headache, tachycardia, and bronchoconstriction. Histamine also increases vascular permeability and potentiates pain. Mequitazine is a histamine H1 antagonist. It competes with histamine for the normal H1-receptor sites on effector cells of the gastrointestinal tract, blood vessels and respiratory tract. It provides effective, temporary relief of sneezing, watery and itchy eyes, and runny nose due to hay fever and other upper respiratory allergies. For the treatment of Hay fever, urticaria (hives) and allergic rhinitis Mechanism Of Action: Mequitazine binds to the histamine H1 receptor sites on effector cells in the gastrointestinal tract, blood vessels, and respiratory tract. This blocks the action of endogenous histamine, which subsequently leads to temporary relief of the negative symptoms brought on by histamine. News Articles on Mequitazine Experimental surveillance using data on sales of over-the-counter … - Aug 26, 2005 ...antihistaminics (eg, carbinoxamine maleate or mequitazine), vitamins (eg, vitamin B1, B2, or vitamin C), and others (eg, herbal medicines or caffeine). ... $4.95 - Morbidity and Mortality Weekly Report - ECNext REGULATORY NEWS IN BRIEF - Sep 19, 2005 The nine ingredients are cyproheptadine HCl, diphenhydramine tannate, mequitazine, metronidazole, setiptiline maleate, risperidone, repirinast, ... Pay-Per-View - Pharma Japan - Factiva, from Dow Jones Brand Names/Synonyms: Mequitazine is also known by the following brand names and/or synonymsButix; CHEMBANK2839; Instotal; Kitazemin; LM 209; LM-209; Mequitazina; Mequitazina [Inn-Spanish]; Mequitazina [Spanish]; Mequitazine; Mequitazine [Ban:Dcf:Inn:Jan]; Mequitazinum [Inn-Latin]; Metaplexan; Mircol; Primalan; Vigigan; Virginan; Zesulan Drug Category: Mequitazine is categorized under the following by the FDA: Bronchodilator Agents; Histamine H1 Antagonists; ATC:R06AD07 Dosage Forms: Tablet Absorption: Not Available Interactions: [an error occurred while processing this directive] Chemical IUPAC Name: 10-(4-azabicyclo[2.2.2]oct-7-ylmethyl)phenothiazine |
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