Methylphenidate

This page contains recent news articles, when available, and an overview of Methylphenidate but does not offer medical advice. You should contact your physician with regard to any health issues or concerns.


Overview:

Methylphenidate
(when available)

Pharmacology and use:
Methylphenidate, a central nervous system stimulant chemically similar to the amphetamines, is used to treat narcolepsy, attention-deficit hyperactivity disorder (ADHD) in children, post-stroke depression or other depressive disorders. Children with attention deficit disorders

Mechanism Of Action:
Methylphenidate blocks dopamine uptake in central adrenergic neurons by blocking dopamine transport or carrier proteins. Methylphenidate acts at the brain stem arousal system and the cerebral cortex and causes increased sympathomimetic activity in the central nervous system. Alteration of serotonergic pathways via changes in dopamine transport may result.

News Articles on Methylphenidate

文化鴻æº?:變è?°æ˜Žçš„æ?·å¾‘  -  05 Jan 2010
...其中的膽鹼酯酵素抑製劑(cholinesterase inhibitors)用來醫治è€?年癡呆症阿爾茨海默病(Alzheimer's disease)患者的èª?知方é?¢çš„症狀,呱醋甲酯(Methylphenidate)則 ... BBC中文網

文化鸿沟:å?˜è?ªæ˜Žçš„æ?·å¾„  -  05 Jan 2010
...其中的胆碱酯酶抑制剂(cholinesterase inhibitors)用æ?¥åŒ»æ²»è€?年痴呆症阿尔茨海默病(Alzheimer's disease)患者的认知方é?¢çš„症状,哌醋甲酯(Methylphenidate)则 ... BBC 中文网

Non-safety-related voluntary recall of a limited portion of Daytrana ...  -  ‎Dec 11, 2009‎
Shire plc , the global specialty biopharmaceutical company, announced a voluntary recall of five lots and voluntary market withdrawal of one lot of the ... Behavioral Health Central (blog)

Marshall man, Charles Howard Allen Jr,... with prescription fraud  -  ‎Jan 3, 2010‎
He also tried to get methylphenidate twice. He was released from the Buncombe County Detention Facility on a written promise to appear. ... Asheville Citizen-Times

Pharmacy robbery suspect nabbed  -  ‎Dec 23, 2009‎
At about 9:00 am, a man wearing a black balaclava to cover his face walked into the store, at 2109 Ottawa St., and demanded methylphenidate, ... CBC.ca

Stimulants May Offer Protection in ADHD  -  ‎Dec 24, 2009‎
ADHD treatment in children has been controversial, since the mainstay of treatment is stimulant medications, including methylphenidate and amphetamines. ... Brain Blogger (blog)

Facing Stunted Growth in ADHD Market, Shire Clicks on Twitter  -  ‎Dec 31, 2009‎
For example, the company has been unable to gain much traction for Daytrana, its transdermal patch of the common psycho-stimulant compound methylphenidate, ... BNET

Tired of Being Tired?Cancer-related fatigue doesn't have to slow you down.  -  ‎Dec 23, 2009‎
Stimulants such as Ritalin (methylphenidate), a treatment for attention deficit disorder, and Provigil (modafinil), which is approved for narcolepsy, ... Curetoday.com (press release)

New technology makes ADHD diagnosis more precise  -  ‎Dec 9, 2009‎
Stimulants such as amphetamine, dextroamphetamine, and methylphenidate are commonly used to treat ADHD. These include the brand-name medications Adderall ... Northwest Herald

Avoid a bad drug trip  -  ‎Dec 11, 2009‎
Caffeine in drinks or chocolate also can increase the impact of stimulant drugs such as Ritalin (methylphenidate) and decrease the effect of ... Washington Times

Seizure drug limits aggression in kids with ADHD  -  ‎Dec 14, 2009‎
Doctors typically use stimulants such as Ritalin (methylphenidate) and Adderal (a combination of amphetamines) to treat the main symptoms of ADHD. ... National Post

Assessment of Physical Illness by Mental Health Clinicians During Intake Visits  -  ‎Dec 31, 2009‎
Two psychiatrists referenced treatment guidelines in recommending an electrocardiogram before methylphenidate treatment and a lipid panel during ... Psychiatric Services (subscription)

Neptune Reports Third Quarter Sales Estimate and Business Update  -  ‎Dec 15, 2009‎
At the lowest daily dose of 250mg, NKPL showed a significant effect strongly resembling (by 80% and 100%) the activity of methylphenidate or Ritalin(R), ... CNNMoney.com (press release)

Shire Reports Tolerability and Clinical Effects Results of Daytrana(R ...  -  ‎Oct 30, 2009‎
Daytrana delivers medication directly through the skin into the bloodstream and is designed to release methylphenidate continuously while applied to the ... Reuters

The Ritalin study: Research raises concerns about safety of popular drug  -  ‎Nov 11, 2009‎
HOUSTON -- Most of us know it as Ritalin: the brand name for the drug methylphenidate. For a nearly a half-century, doctors have ... KVUE

Enforcement, regulation of Rx medicines lacking  -  ‎Nov 13, 2009‎
Vicodin, methamphetamine, Alprazolam, heroin and Methylphenidate. Addicts take as many as five of these very addictive and deadly drugs in combination. ... Colusa County Sun Herald

CONCERTA(R) in the Classroom: New Data on Attention in Children With ADHD  -  ‎Nov 4, 2009‎
Abuse of methylphenidate may lead to dependence. Tell your healthcare professional if you or your child has had problems with alcohol or drugs; ... Reuters

Researcher did not die of overdose, autopsy says  -  ‎Nov 13, 2009‎
The most serious include possession of marijuana with intent to distribute and possession of two prescription narcotics, the stimulant methylphenidate ... Baltimore Sun

Shire reports tolerability/clinical effects results of Daytrana from study in ...  -  ‎Nov 2, 2009‎
Daytrana delivers medication directly through the skin into the bloodstream and is designed to release methylphenidate continuously while applied to the ... PhysOrg.com

HealthFirst-Exercising your memory  -  ‎Nov 13, 2009‎
ADD MEDICATIONS: The most common drugs used to treat ADD are methylphenidate (Ritalin, Concerta, Daytrana), dextroamphetamine-amphetamine (Adderall), ... ABC12.com

ADHD Drugs Killed Their Son, Parents Say  -  ‎Oct 29, 2009‎
The Kansas couple says the drug makers never warned them that the drug combination could kill their son with methylphenidate toxicity. ... Courthouse News Service

Plummeting Adderall XR sales drag on Shire's quarter  -  ‎Nov 3, 2009‎
Furthermore, the group also anticipates further expanding its ADHD franchise next year with the launch of Daytrana (methylphenidate) for adolescents in the ... Pharma Times

In court Monday:  -  ‎Nov 4, 2009‎
MAURO, James V., 44, Boston; possession of cocaine, possession of Hydrocodone, possession of methylphenidate, possession of Xanax as a subsequent offense ... Cape Cod Times

Two 17 Year Old's Arrested In Monterey  -  ‎Oct 25, 2009‎
Ritalin (methylphenidate), Bates found, is similar in nature to Cocaine. It is the most common drug prescribed for Attention Deficit Disorder. ... UC Daily News

Off the Deep End: Prescription drug abuse is not a small problem  -  ‎Nov 11, 2009‎
Stimulants for ADHD and narcolepsy are also abused and include dextroamphetamine or Dexedrine, methylphenidate brand name Ritalin and Concerta, ... Lake County Record-Bee

Band-Aid Won't Stop Generic Bleeding at Johnson & Johnson  -  ‎Nov 11, 2009‎
Further patent risks to stateside sales include exclusivity challenges to the attention deficit disorder medicine Concerta (methylphenidate), ... BNET

Getting Kids Off Meds  -  ‎Nov 9, 2009‎
ADD MEDICATIONS: The most common drugs used to treat ADD are methylphenidate (Ritalin, Concerta, Daytrana), dextroamphetamine-amphetamine (Adderall), ... ABC7Chicago.com

Government Adviser Fired For Saying Alcohol Is More Dangerous Than Drugs  -  ‎Nov 1, 2009‎
Class B includes cannabis, amphetamine, codeine and methylphenidate ("Ritalin"). Finally, Class C includes GHB, ketamine, diazepam, flunitrazepam and most ... Huffington Post (blog)

EU Committee To Size Up Abbott, Solvay Cholesterol Drugs  -  ‎Oct 26, 2009‎
A recent example of a referral procedure was the EMEA's review of medicines containing methylphenidate, which treat attention-deficit hyperactivity disorder ... Wall Street Journal

Over And Out  -  ‎Nov 5, 2009‎
For a teen with ADD, the methylphenidate in the pill stimulates certain receptors in the brain and helps a diagnosed patient focus and stay calm. ... LongIslandPress.com

Before Prozac: The Troubled History of Mood Disorders in Psychiatry  -  ‎Nov 2, 2009‎
Methylphenidate, first synthesized by the Ciba chemist Leandro Panizzon, was named Ritalin after his wife, Marguerite (Rita). Shorter tells us that both she ... Am J Psychiatry (subscription)

Smart Pills: More Focus or Hocus Pocus?  -  ‎Oct 29, 2009‎
Examples include stimulants such as Ritalin (methylphenidate) and Adderall (amphetamine/dextroamphetamine combination)—the drugs used for children with ... HealthNewsDigest.com

Births and nubs of the news  -  ‎Oct 29, 2009‎
Possession of methylphenidate: Kalee J. Kicksey, YOB 1985, Bismarck, deferred sentence for three years with supervised probation, also possession of ... Bismarck Tribune

Woman charged after drug raid  -  ‎Oct 24, 2009‎
Johnson, who was free on bail at the time, was in possession of ecstasy, marijuana and methylphenidate, marketed as Ritalin, according to indictments ... The Keene Sentinel

Drugs database to make police work easier, faster  -  ‎Oct 21, 2009‎
It showed restricted drugs, such as morphine sulphate, Ritalin (methylphenidate) and codeine. "The main benefit to staff is a reduction in the time it can ... Timaru Herald

Promising early results for UCB's new products  -  ‎Oct 22, 2009‎
...declined due to the mild cough and cold season in the US earlier in the year, while net sales of Metadate(TM) CD (methylphenidate) increased. ... The FINANCIAL

“è?ªæ˜Žè?¯â€?真有效å?—?  -  ‎Nov 10, 2009‎
...å?ˆæ³•的精神兴奋剂包括苯哌啶醋酸甲酯(methylphenidate,å?³åˆ©ä»–æž—)ã€?安é?žä»–明(amphetamine)å?ŠèŽ«è¾¾é?žå°¼(modafinil)。æ?®æŠ¥é?“,在æŸ?些学校,1/4的学生都在æœ?用这些è?¯ç‰©ã€‚ ... 中青在线

大学生和白领æµ?行å?ƒçš„“è?ªæ˜Žè?¯â€?真有效?  -  ‎Nov 9, 2009‎
...å?ˆæ³•的精神兴奋剂包括苯哌啶醋酸甲酯(methylphenidate,å?³åˆ©ä»–林)ã€?安é?žä»–明(amphetamine)å?ŠèŽ«è¾¾é?žå°¼ï¼ˆmodafinil)。æ?®æŠ¥é?“,在æŸ?些学校,1/4的学生都在æœ?用这些 ... 人民网

è?ªæ˜Žè?¯è®©å¤§è„‘快速充电?  -  ‎Nov 4, 2009‎
...æ ¹æ?®ç¾Žå›½æ”¿åºœåœ¨2007å¹´æ?œé›†çš„资料,超过160万å??美国人在一年内曾因é?žåŒ»ç–—目的而使用需è¦?处方的兴奋剂,属于这个类别的å?ˆæ³•è?¯ç‰©åŒ…括派醋甲酯(methylphenidate,商å“?å??为 ... 中新网

ç’°ç?ƒç§‘學:è?°æ˜Žè—¥æƒ¹è³ªç–‘(組圖)  -  ‎Nov 6, 2009‎
...å?ˆæ³•的精神興奮劑包括苯呱啶醋酸甲酯(methylphenidate,å?³åˆ©ä»–æž—)ã€?安é?žä»–明(amphetamine)å?ŠèŽ«é?”é?žå°¼(modafinil)。據報導,在æŸ?些學校,1/4的學生都在æœ?用這些藥物。 ... 臺灣新浪網

Bổ ngá»­a vì... thuốc bổ óc  -  ‎Oct 20, 2009‎
Còn thuốc dextroamphetamine (biệt dược Dexedrine), methylphenidate (Ritalin) là thuốc kích thích hệ thần kinh được dùng chá»§ yếu trị bệnh gá»?i là “rối loạn ... Thanh Niên

Mehr Probleme mit der Psyche  -  ‎Oct 29, 2009‎
Häufig dafür missbrauchte Medikamente sind laut Krankenkasse beispielsweise Methylphenidate wie „Ritalin�, die eigentlich gegen Aufmerksamkeitsstörungen ... Derwesten.de

ריטלין וטיפול ב-ADHD ×?צל ילדי×?  -  ‎Nov 2, 2009‎
...ריטלין, הידוע בשמו הרפו×?×™ "methylphenidate", הינו תרופה ממשפחת החומרי×? המעוררי×? ופועל בעיקר על ידי חסימת החלבון המוביל לדופ×?מין שעל קרו×? ת×?×™ העצב במוח. ... BeOK פורטל בריאות ויופי

è?°æ˜Žè—¥å¹«å¤§è…¦å¿«é€Ÿå……電?  -  ‎Oct 28, 2009‎
...根據美國政府在2007å¹´è’?集的資料,超é?Ž160è?¬å??美國人在一年內曾因é?žé†«ç™‚目的而使用需è¦?處方的興奮劑,屬於這個類別的å?ˆæ³•藥物包括派醋甲酯(methylphenidate,商å“?å??為 ... 科學人雜誌 (需訂閲)

Rối loạn giấc ngá»§ ở ngưá»?i cao tuổi  -  ‎Oct 27, 2009‎
...dùng các chất gây hưng phấn trước khi ngá»§ như: trà, cà phê, nước ngá»?t có gas... hay má»™t số loại thuốc như Amphetamin, Methylphenidate. ... Báo Hoà Bình

Rapport intermédiaire - Premiers résultats prometteurs pour les nouveaux ...  -  ‎Oct 21, 2009‎
Les ventes nettes de Metadate(TM) CD (methylphenidate) ont par contre progressé. Les données concernant les prescriptions de Cimzia (certolizumab pegol) ... Euronext (persbericht)

“è?ªæ˜Žè?¯â€?争议:æ??高智商还是使人æˆ?瘾?  -  ‎Nov 5, 2009‎
...å?ˆæ³•的精神兴奋剂包括苯哌啶醋酸甲酯(methylphenidate,å?³åˆ©ä»–林)ã€?安é?žä»–明(amphetamine)å?ŠèŽ«è¾¾é?žå°¼ï¼ˆmodafinil)。æ?®æŠ¥é?“,在æŸ?些学校,1/4的学生都在æœ?用这些 ... 网易

Tussentijds rapport - Veelbelovende eerste resultaten voor nieuwe producten ...  -  ‎Oct 21, 2009‎
...van het zachte hoest- en verkoudhedenseizoen in de VS eerder dit jaar, terwijl de nettoverkoop van Metadate(TM) CD (methylphenidate) is gestegen. ... Analist.be (persbericht)

Prevalence of methylphenidate use among Canadian children following …  -  Jun 5, 2007
Background: Evidence suggests that children living in single-parent or step-parent households are more likely than children in households with 2 biological ... Free with registration - CMAJ: Canadian Medical Association... - AccessMyLibrary.com

FDA OKs first attention deficit patch  -  Apr 6, 2006
Approval of the patch comes as use of methylphenidate and other ADHD drugs ... Methylphenidate — in any form — cannot be taken if sensitization occurs. ... msnbc.com

Drugmaker awaits decision on attention deficit drug patch - Nov. 30,...  -  Nov 30, 2005
The failure of the generic pain patch leaves investors "paying little for the company's next potential product, a patch version of methylphenidate," ... CNNMoney.com

Pencils, pens, meds  -  Aug 20, 2007
One ad touts a flavored, chewable form of methylphenidate with the slogan, "Give me the grape." (Methylphenidate is best known under the trade name Ritalin, ... Los Angeles Times

Doctors told to curb use of Ritalin in hyperactive children  -  Sep 24, 2008
Drugs such as Ritalin and Concerta (brand names for methylphenidate) and Strattera (atomoxetine) should be used as frontline treatments only when severe ... Times Online

New warnings due for ADHD drugs  -  Jun 29, 2005
At a meeting today of the FDA's Pediatric Advisory Committee, officials will discuss safety concerns about Concerta, a form of methylphenidate, the active ... USA Today

ADHD medications: Skin patch an option for kids  -  Apr 10, 2006
The patch, sold under the brand name Daytrana, contains methylphenidate — the ... As with other forms of methylphenidate, other side effects may include ... CNN

Methylphenidate Hydrochloride Increases Energy Expenditure in Healthy...  -  Jan 11, 2007
To examine the effects of methylphenidate hydrochloride (MPH) on resting energy expenditure (REE) and postprandial energy expenditure (PEE) and substrate ... Nature.com

ADHD Medications Don't Pose Cancer Risk  -  Nov 21, 2008
The new study, which looked at methylphenidate (Ritalin LA and Concerta) and amphetamine (Adderall and Adderall XR), used a larger study sample and ... BusinessWeek

ADHD Skin Patch Gets Approved  -  Apr 7, 2006
The skin patch contains methylphenidate, the same ingredient found in Ritalin, another ADHD drug made by Novartis (NVS - commentary - Cramer's Take) and by ... TheStreet.com - TheStreet.com (subscription)

Consumers Union: ADHD Drugs Overprescribed  -  Sep 28, 2005
Consumer Reports names several forms of the stimulant methylphenidate as a best buy, ... Methylphenidate is also contained in the well-known brand-name drug ... FOXNews

Brain boost drugs 'growing trend'  -  Oct 13, 2008
..."Methylphenidate does have substantial abusive potential so we have to be worried about substance abuse problems and the use of these drugs in the ... BBC News

New ADHD drugs reduce likelihood of abuse  -  May 29, 2007
Daytrana delivers methylphenidate through a skin patch with the dosage ... Findling's team compared the patch with oral methylphenidate and placebo in 270 ... Reuters UK

Influence of Ethanol and Gender on Methylphenidate Pharmacokinetics …  -  Jan 6, 2006
Jaffe, SL Intranasal abuse of prescribed methylphenidate by an alcohol and drug ... Bioequivalence of methylphenidate immediate-release tablets using a ... Nature.com

Alarm as prescriptions of Ritalin to children reach a record high  -  Sep 20, 2005
Prescriptions of Methylphenidate - most commonly sold as Ritalin - rose to 359100 last year, ... "While Methylphenidate undoubtedly works for some children, ... Telegraph.co.uk

ADHD Medications Don't Pose Cancer Risk  -  Nov 19, 2008
The new study, which looked at methylphenidate (Ritalin LA and Concerta) and amphetamine (Adderall and Adderall XR), used a larger study sample and ... ABC News

… Data Suggests Less Abuse-Related Effects For OROS® Methylphenidate  -  May 29, 2007
Stimulant drug abuse remains an ongoing concern for parents and physicians who prescribe medications to treat Attention Deficit Hyperactivity Disorder ... Medical News Today - Medical News Today (press release)

Hidden dangers of failure to diagnose ADHD correctly  -  Apr 1, 2006
The success of stimulants such as methylphenidate in treating ADHD is unprecedented in psychiatry. Unlike antidepressants, which work well in only about ... New Scientist

FDA plans stronger warning for ADHD drug  -  Jul 1, 2005
A subsequent review of all methylphenidate products found similar reports. The FDA can't say if the drugs actually cause those side effects — the reports ... Seattle Times

ADHD drug cuts adults' calorie, fat intake  -  Sep 4, 2007
Weight loss is known to be a potential side effect of methylphenidate, ... "I would say that since methylphenidate ... reduced food intake and fat intake in ... The Australian

FDA Approves CONCERTA(R) (Methylphenidate HCI) Extended-Release …  -  Jun 27, 2008
RARITAN, NJ, June 27 /PRNewswire/ -- ADHD is the most common emotional, cognitive and behavioral disorder treated in children(1), and according to the ... RedOrbit

ADD TREATMENT PATCH IS SAFE, FDA PANEL SAYS  -  Dec 3, 2005
The advisers said they are concerned about the rare possibility that some children might become "sensitized" to the patch's medicine, methylphenidate. ... Pay-Per-View - South Florida Sun - Sentinel - ProQuest Archiver

Methylphenidate patch: committee supports warning: sensitization …  -  Jan 1, 2006
Gaithersburg, MD, -- A federal advisory committee has supported approval of a transdermal methylphenidate patch for treating ADHD in children--with a caveat ... Free with registration - Pediatric News - AccessMyLibrary.com

Brain chemical has key role in ADHD: studies  -  Aug 6, 2007
The usual treatment for ADHD may include drugs like Ritalin, or methylphenidate, a stimulant intended to lower impulsiveness and hyperactivity and boost ... Reuters UK

Meth Comes Out of the Closet; In Parts of Washington's Gay Community,...  -  Nov 8, 2005
Researchers have suggested that, like crystal meth, methylphenidate amplifies the brain's release of dopamine, thereby improving attention and focus in ... Pay-Per-View - Washington Post - ProQuest Archiver

Noven Provides Update on Daytrana(TM) Methylphenidate Transdermal …  -  Nov 28, 2006
MIAMI -- Noven Pharmaceuticals, Inc. (NASDAQ:NOVN) today provided an update on production and prescription information related to its Daytrana[TM] ... Free with registration - Business Wire - AccessMyLibrary.com

Shire withdraws some ADHD skin patches  -  Sep 4, 2007
Daytrana patches contain methylphenidate, a central nervous system stimulant. The US Food and Drug Administration supports the company's withdrawal. ... Reuters

… Study Showed OROS(R) Methylphenidate Tablets Significantly...  -  May 19, 2008
Adults with attention deficit hyperactivity disorder (ADHD) treated in an investigational study with OROS® methylphenidate tablets experienced significantly ... Medical News Today - Medical News Today (press release)

ADHD - Positive study results for methylphenidate transdermal system  -  Oct 26, 2005
Shire announced at a major medical meeting in Toronto, Canada, that its investigational methylphenidate transdermal system (MTS) demonstrated statistically ... Medical News Today - Medical News Today (press release)

… use of ADHD therapy: transdermal methylphenidate approved.(care...  -  May 1, 2006
The Food and Drug Administration's approval of a transdermal methylphenidate patch for the treatment of attention-deficit hyperactivity disorder in children ... Free with registration - Clinical Psychiatry News - AccessMyLibrary.com

Ritalin may help elderly avoid falls  -  Jul 29, 2008
WASHINGTON - The medication Ritalin (methylphenidate), often prescribed to treat hyperactive children, may also be used to prevent elderly people from ... Channel News Asia

… Suggests Less Abuse-Related Effects For OROS(R) Methylphenidate  -  May 24, 2007
..."Although methylphenidate is proven to be an effective treatment for ADHD, ... A review of this data found that OROS(R) methylphenidate had a lower ... Medical News Today - Medical News Today (press release)

… Effective in Patients Converted From Oral Long-Acting Methylphenida...  -  Oct 31, 2006
PHILADELPHIA, PA -- October 31, 2006 -- Shire plc announced today that its Attention Deficit Hyperactivity Disorder (ADHD) patch Daytranaâ„¢ (methylphenidate ... DG News

… to higher daily doses of methylphenidate.(Conference Notes)(Attenti...  -  Jan 1, 2005
In recently presented findings, researchers suggested that once-daily methylphenidate (Concerta) at doses of 36-54 mg was more effective than either once ... Free with registration - Brown University Psychopharmacology... - AccessMyLibrary.com

Call for re-think on stimulants for ADHD  -  Feb 4, 2008
Professor Rey recounts the results of a US study that compared methylphenidate (Ritalin), psychosocial treatment and routine community care for 579 children ... 6minutes

Europe's health sector faces ADHD cost spike  -  Nov 15, 2007
Treatment often includes drugs like Ritalin, or methylphenidate, a stimulant intended to curb impulsiveness and hyperactivity and boost attention. ... Reuters UK

… Shorter DAYTRANA(TM) (methylphenidate transdermal system) Wear …  -  May 25, 2006
As with other products containing methylphenidate (the active ingredient in ... DAYTRANA should not be used by children allergic to methylphenidate or other ... Free with registration - PR Newswire - AccessMyLibrary.com

Methylphenidate Shows Promise In The Treatment Of Hyperactivity …  -  Nov 8, 2005
By JAMA/Archives, [RxPG] Medication commonly used to treat attention-deficit hyperactivity disorder (ADHD) may be effective for treatment of hyperactivity ... RxPG NEWS

Gov't adds two new ADHD drugs to formulary to combat Ritalin abuse  -  Jul 18, 2008
Medications such as Ritalin, containing the active drug methylphenidate, have become a popular street injection drug because they are easily dissolved. ... Canada.com

DAYTRANA (methylphenidate transdermal system) significant reduces …  -  May 24, 2006
Philadelphia, US – Shire plc (LSE: SHP, NASDAQ: SHPGY, TSX: SHQ) announced that its methylphenidate transdermal system (MTS), DAYTRANA TM demonstrated ... PsychCentral.com

Methylphenidate (Systemic).  -  Jul 28, 2005
Methylphenidate (meth-il-FEN-i-date) belongs to the group of medicines called central nervous system (CNS) stimulants. It is used to treat attention-deficit ... Free with registration - USP DI-Volume II, Advice for the... - AccessMyLibrary.com

Increased Rates Of Methylphenidate Use In Children Following Parental...  -  Jun 10, 2007
Divorce can be a predictor of subsequent methylphenidate use by children of broken families, according to a University of Alberta study. ... Medical News Today - Medical News Today (press release)

Depression (PDQ®)  -  Dec 19, 2008
Clinical experience suggests that analeptic agents (eg, methylphenidate and ... Methylphenidate and dextroamphetamine are administered in divided doses ... WebMD

Methylphenidate (Systemic).(Drug overview)  -  Aug 1, 2006
Methylphenidate (meth-il-FEN-i-date) belongs to the group of medicines called central nervous system (CNS) stimulants. It is used to treat attention-deficit ... Free with registration - USP DI-Volume II, Advice for the... - AccessMyLibrary.com

Drug helps ADHD children with poor sleep  -  Aug 2, 2007
2 (UPI) -- Children with attention deficit hyperactivity disorder and poor sleep efficiency improved reaction time after taking methylphenidate, a Canadian ... United Press International

FDA Issues Approvable Letter for Daytrana(TM) Methylphenidate …  -  Dec 23, 2005
...today that the US Food and Drug Administration (FDA) has issued an approvable letter relating to Daytrana(TM) (methylphenidate transdermal system), ... RedOrbit

… atomoxetine and twice-daily methylphenidate equally effective...  -  Apr 1, 2006
Response rates were 77% for atomoxetine and 81% for methylphenidate--not a statistically significant difference. The total score changes on the parents' ... Free with registration - Pediatric News - AccessMyLibrary.com

Funding for ADHD drug  -  Aug 20, 2008
Concerta will be the third form of methylphenidate it subsidises. Pharmac says the immediate-release and sustained-release versions it pays for now are ... New Zealand Herald

Does methylphenidate cause a cytogenetic effect in children with …  -  Jun 1, 2007
BACKGROUND AND OBJECTIVE: Attention deficit hyperactivity disorder (ADHD) is the most common psychiatric disorder in children and adolescents (6-12% ... Free with registration - Environmental Health Perspectives - AccessMyLibrary.com

Helping kids with ADHD  -  Aug 18, 2005
These are Methylphenidate (Ritalin) and Dexamphetamine. ... Recently, a sustained release form of Methylphenidate has also become available and is very ... Malaysia Star

FDA approves patch for ADHD  -  Apr 18, 2006
Approval of the patch comes as use of methylphenidate and other ADHD drugs increases. Nearly 3.3 million Americans age 19 and younger used an ADHD drug last ... Pay-Per-View - Chicago Tribune - ProQuest Archiver

Ritalin funded again after alternative causes side effects  -  Sep 27, 2007
Pharmac switched its funding from ritalin to rubifen another, cheaper, methylphenidate medicine earlier this year. Medsafe interim manager Dr Stewart ... New Zealand Herald

Small study ties Ritalin to higher cancer risk.  -  Feb 25, 2005
The study is the first to look at the potential chromosome-damaging effects associated with methylphenidate, the generic name for Ritalin, the most widely ... Free with registration - Houston Chronicle - AccessMyLibrary.com

Noven Provides Update on Daytrana(TM) Methylphenidate Transdermal …  -  Jun 9, 2008
Noven Pharmaceuticals, Inc. (NASDAQ:NOVN) today provided an update on the status of Daytrana(TM), the only transdermal patch indicated for the treatment of ... Genetic Engineering News - Genetic Engineering News (press release)

… events following risperidone-to-methylphenidate switch.(Case...  -  May 1, 2007
All 3 cases resolved upon discontinuation of methylphenidate. In 2 cases, methylphenidate was re-administered after a drug-free interval, ... Free with registration - Brown University Child and Adolescent... - AccessMyLibrary.com

Daytrana.(methylphenidate transdermal system for treatment of...  -  May 1, 2006
This central nervous system stimulant delivered via a transdermal patch is the first and only non-oral therapy to receive approval for the treatment of ... Free with registration - Formulary - AccessMyLibrary.com

… That ADHD Patients on CONCERTA(R) (Methylphenidate HCl) Are More …  -  Jun 28, 2005
NEW YORK, June 28 /PRNewswire/ -- The results of a new analysis of data by Columbia University Medical Center and New York State Psychiatric Institute ... $4.95 - PR Newswire - ECNext

Taking Methylphenidate Transdermal from Consumer Reports Health.  -  Jan 6, 2007
Methylphenidate can be habit-forming. Do not apply more patches, apply the patches more often, or ... Full Alert. Methylphenidate may cause side effects. ... consumerreports.org

Study looks at effect of methylphenidate on young ADHD drivers  -  May 4, 2007
When a song on the radio or the cell phone on the car seat next to a young driver beckon, she may not resist the temptation to turn up the dial or take a ... News-Medical.net

Noven Provides Update on Daytrana(R) Methylphenidate Transdermal …  -  Aug 25, 2008
Noven Pharmaceuticals, Inc. (NASDAQ:NOVN) today provided an update on the status of Daytrana(R), the only transdermal patch indicated for the treatment of ... Genetic Engineering News - Genetic Engineering News (press release)

… -Deficit Hyperactivity Disorder; Methylphenidate linked to chromosom...  -  Mar 26, 2005
2005 MAR 26 - (NewsRx.com) -- In a small but startling preliminary new study, Texas researchers have found that after just 3 months, every one of a dozen ... Pay-Per-View - Obesity, Fitness & Wellness Week - Factiva, from Dow Jones

Study Shows Methylphenidate Linked to Chromosomal Changes  -  Feb 28, 2005
In a small but startling preliminary new study, Texas researchers have found that after just three months, every one of a dozen children treated for ... Medical News Today - Medical News Today (press release)

… Potential Of Leading ADHD Medication, CONCERTA® (methylphenidate …  -  Nov 3, 2006
The study found that immediate-release methylphenidate produced greater subjective ... Its leading pediatric product, CONCERTA® (methylphenidate HCl) ... Medical News Today - Medical News Today (press release)

… Methylphenidate and Lisdexamfetamine: Transdermal Methylphenidate  -  Apr 6, 2006
On April 6, 2006, the FDA approved the first methylphenidate transdermal system (MTS) for the management of ADHD in children 6 to 12 years of age. ... Medscape

Information For Patients Taking Concerta Or Their Parents Or Caregiver...  -  Dec 30, 2006
Before taking concerta tell your doctor if child are pregnant or plan on becoming pregnant If methylphenidate is taken, it may be in breast milk. ... Pittsburgh Post-Gazette - Google News Archive

Positive study results for methylphenidate transdermal system  -  Nov 11, 2005
Shire announced at the US Psychiatric and Mental Health Congress in Las Vegas, Nevada, that its investigational methylphenidate transdermal system (MTS) ... eurekalert.org

Positive study results for methylphenidate transdermal system  -  Oct 24, 2005
Philadelphia, US – October 24, 2005 – Shire announced at a major medical meeting in Toronto, Canada, that its investigational methylphenidate transdermal ... eurekalert.org

Learn about Methylphenidate from Consumer Reports Health.  -  Jan 6, 2007
Methylphenidate can be habit-forming. Do not take a larger dose, take it more often, take it for a ... Full Alert. Methylphenidate is used as part of a ... consumerreports.org

Learn about Methylphenidate Transdermal from Consumer Reports …  -  Jan 6, 2007
Methylphenidate can be habit-forming. Do not apply more patches, apply the patches more often, or ... Full Alert. Methylphenidate transdermal patches are ... consumerreports.org

Methylphenidate reduces fatigue safely in hospice patients.(care and ...  -  May 1, 2006
NASHVILLE, TENN. -- Treatment with methylphenidate safely reduced fatigue and depression in hospice patients in a controlled study with 30 patients. ... Free with registration - Clinical Psychiatry News - AccessMyLibrary.com

Atomoxetine and Methylphenidate Appear Equal in Clinical Efficacy for...  -  Oct 27, 2005
By Mark Pownall. AMSTERDAM, THE NETHERLANDS -- October 27, 2005 -- The attention deficit/hyperactivity disorder (ADHD) treatments methylphenidate and ... DG News

ADHD/Narcolepsy Drug Recalled  -  Feb 9, 2005
...by the manufacturer, Mallinckrodt Inc. of St. Louis, found that tablets of all dosage strengths may have too much or too little methylphenidate. ... CBS News

… Hyperactivity Disorder; US FDA approves methylphenidate patch to...  -  May 11, 2006
Daytrana is a once daily treatment containing the drug methylphenidate, ... Has allergies to methylphenidate or other ingredients in Daytrana. ... Pay-Per-View - Health & Medicine Week - Factiva, from Dow Jones

… Deliver Steady Pharmacokinetics of Methylphenidate: Presented at...  -  Sep 12, 2007
..."The methylphenidate transdermal system 20 cm 2 once-daily patch worn daily for 7 ... [Presentation title: Pediatric Pharmacokinetics of a Methylphenidate ... DG News

How to take Methylphenidate from Consumer Reports Health.  -  Jan 6, 2007
Methylphenidate can be habit-forming. Do not take a larger dose, take it more often, take it for a ... Full Alert. tell your doctor and pharmacist if you ... consumerreports.org

Taking Methylphenidate from Consumer Reports Health.  -  Jan 6, 2007
Methylphenidate can be habit-forming. Do not take a larger dose, take it more often, take it for a ... Full Alert. Methylphenidate may cause side effects. ... consumerreports.org

How to take Methylphenidate Transdermal from Consumer Reports …  -  Jan 6, 2007
Methylphenidate can be habit-forming. Do not apply more patches, apply the patches more often, or ... Full Alert. tell your doctor and pharmacist if you are ... consumerreports.org

McNeil Pediatrics Presents Data on CONCERTA(R) (methylphenidate …  -  Jul 17, 2006
Abuse of methylphenidate may lead to dependence. ... Its leading pediatric product, CONCERTA(R) (methylphenidate HCl) Extended-release Tablets, ... Free with registration - PR Newswire - AccessMyLibrary.com

Alternatives to drugs for ADHD preschooler  -  Sep 5, 2007
The Harvard Mental Health Letter advised the first large, controlled trial of methylphenidate -- also known as Ritalin and others -- in children aged 3 to 5 ... United Press International

… Potential of Leading ADHD Medication, CONCERTA(R) (Methylphenidate …  -  Oct 27, 2006
The study found that immediate-release methylphenidate produced greater subjective ... Its leading pediatric product, CONCERTA(R) (methylphenidate HCl) ... RedOrbit

… Children With ADHD Not Linked to Methylphenidate: Presented at AACAP  -  Nov 1, 2007
Subjects in the methylphenidate transdermal group received 10-mg, 15-mg, ... After 5 weeks, among the methylphenidate transdermal, methylphenidate oral or ... DG News

Methylphenidate Transdermal System (Daytranaâ„¢)  -  Jun 15, 2006
By William T. Elliott, MD, FACP, and James Chan, PhD, PharmD, Dr. Elliott is Chair, Formulary Committee, Northern California Kaiser Permanente; ... Free with registration - Internal Medicine Alert - AccessMyLibrary.com

McNeil Pediatrics Presents Data On CONCERTA(R) (methylphenidate …  -  Jul 18, 2006
Abuse of methylphenidate may lead to dependence. ... Its leading pediatric product, CONCERTA(R) (methylphenidate HCl) Extended-release Tablets, ... Medical News Today - Medical News Today (press release)

… : FDA Approves CONCERTA(R) (methylphenidate HCI) Extended-release …  -  Jun 27, 2008
FDA Approves CONCERTA(R) (methylphenidate HCI) Extended-release Tablets for Treatment of ADHD (Attention Deficit Hyperactivity Disorder) in Adults. from PR ... Pay-Per-View - PR Newswire - HighBeam Research

ADHD prescriptions may face govt inquiry  -  Jul 8, 2006
Novartis also warned against the long-term use of methylphenidate - which covers drugs branded Ritalin, Attenta and Concerta - because of incomplete safety ... The Age

Effect of low-dose methylphenidate on comorbid ADHD/SUDs limited.( …  -  Apr 1, 2006
A double-blind, placebo-controlled pilot study failed to show any definite effect of methylphenidate on adult patients with attention deficit/hyperactivity ... Free with registration - Brown University Digest of Addiction... - AccessMyLibrary.com

Methylphenidate use and divorce.(Letters)  -  Sep 25, 2007
The findings in a CMAJ research article by Lisa Strohschein on methylphenidate use among Canadian children are likely to be misinterpreted because of the ... Free with registration - CMAJ: Canadian Medical Association... - AccessMyLibrary.com

What are the effects of methylphenidate treatment in preschoolers...  -  Dec 1, 2006
This issue of The Update presents an overview of the key findings from the Preschool ADHD Treatment Study (PATS). The landmark study is the first long-term ... Free with registration - Brown University Child and Adolescent... - AccessMyLibrary.com

Methylphenidate Side Effects from Consumer Reports Health.  -  Jan 6, 2007
Methylphenidate can be habit-forming. Do not take a larger dose, take it more often, take it for a ... Full Alert. Methylphenidate can be habit-forming. ... consumerreports.org

Methylphenidate Transdermal Side Effects from Consumer Reports …  -  Jan 6, 2007
Methylphenidate can be habit-forming. Do not apply more patches, apply the patches more often, or ... Full Alert. Methylphenidate can be habit-forming. ... consumerreports.org

… Study Demonstrates Long-Acting Methylphenidate Effective In...  -  Feb 8, 2006
The average doses of immediate release methylphenidate and once daily ... CONCERTA XL is a once-daily, long-acting formulation of methylphenidate and is ... Medical News Today - Medical News Today (press release)

… , Inc. Releases CONCERTA(R) (methylphenidate HCl) Extended-releas  -  Mar 20, 2006
Abuse of methylphenidate may lead to dependence. ... Methylphenidate may produce difficulties with accommodation and blurring of vision. ... Free with registration - PR Newswire - AccessMyLibrary.com

Methylphenidate may reduce hyperactivity in autistic kids.(care and …  -  May 1, 2006
TUCSON, ARIZ. -- Two new studies support the use of methylphenidate in treating hyperactivity in children with autism. The results contradict much of the ... Free with registration - Clinical Psychiatry News - AccessMyLibrary.com

Lifting The Curtain On How Ritalin Packs Its 1-2 Punch  -  May 30, 2006
Methylphenidate, prescribed under the brand name Ritalin, has been used for more ... "If we can show exactly how methylphenidate works, we may be able to ... sciencedaily.com

Drug Delivery; Non-oral methylphenidate transdermal patch system for ...  -  May 8, 2006
2006 MAY 8 - (NewsRx.com) -- Shire plc (SHP) announced that the US Food and Drug Administration (FDA) approved Daytrana (methylphenidate transdermal system) ... Pay-Per-View - Mental Health Weekly Digest - Factiva, from Dow Jones

Abrupt Conversion From Oral Methylphenidate to a Transdermal Patch: …  -  May 25, 2006
By Danny Kucharsky. TORONTO, CANADA -- May 25, 2006 -- Children with attention deficit/hyperactivity disorder (ADHD) who were abruptly converted from oral ... DG News

ADHD preschoolers tolerate methylphenidate.(Behavioral Pediatrics)( …  -  Jan 1, 2007
A dverse events were well tolerated in a majority of 3- to 5-year-olds who took methylphenidate for attention-deficit hyperactivity disorder, based on data ... Free with registration - Pediatric News - AccessMyLibrary.com

ADHD Appears to Be Associated With Depressed Dopamine Activity in …  -  Aug 9, 2007
In individuals with ADHD, methylphenidate caused less of a decrease in the ... Since levels of methylphenidate in the blood were the same in both groups, ... allamericanpatriots.com

Meds Help Preschoolers with ADHD  -  Oct 17, 2006
Methylphenidate is the most commonly prescribed medication to treat children ... The study then compared the effectiveness of methylphenidate to placebo. ... PsychCentral.com

Methylphenidate may be effective in treating autism  -  Nov 26, 2005
Methylphenidate, a medication used to treat attention-deficit hyperactivity disorder (ADHD), may be effective in treating hyperactivity symptoms in children ... News-Medical.net

Brand Names/Synonyms:
Methylphenidate is also known by the following brand names and/or synonyms4311/B Ciba; C 4311; CHEMBANK1663; Calocain; Centedein; Centedrin; Centedrine; Centredin; Concerta; Dea No. 1724; Focalin; Focalin Xr; HSDB 3126; METHYLPHEN; Meridil; Metadate; Metadate Cd; Metadate Er; Methyl Phenidyl Acetate; Methylin; Methylin Er; Methylofenidan; Methylphenidan; Methylphenidate; Methylphenidate Hcl; Methylphenidate Hydrochloride; Methylphenidatum [Inn-Latin]; Methylphenidylacetate Hydrochloride; Methypatch; Metilfenidat Hydrochloride; Metilfenidato [Inn-Spanish]; Metilfenidato [Italian]; Phenidylate; Plimasine; Pms-Methylphenidate; Riphenidate; Ritalin; Ritalin Hydrochloride; Ritalin La; Ritalin Sr; Ritalin-Sr; Ritaline; Ritcher Works

Drug Category:
Methylphenidate is categorized under the following by the FDA: Adrenergic Agents; Dopamine Agents; Central Nervous System Agents; Anorexigenic Agents; Stimulants; ATC:N06BA04

Dosage Forms:
Tablets, SR tablets

Absorption:
readily absorbed in a biphasic manner. It reaches peak absorption at approximately two hours for the first phase and five hours for the second phase. bioavailability is low (approx. 30%)

Interactions:
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Chemical IUPAC Name:
methyl2-phenyl-2-(2-piperidyl)ethanoate





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