Methylphenidate

This page contains recent news articles, when available, and an overview of Methylphenidate but does not offer medical advice. You should contact your physician with regard to any health issues or concerns.


Overview:

Methylphenidate
(when available)

Pharmacology and use:
Methylphenidate, a central nervous system stimulant chemically similar to the amphetamines, is used to treat narcolepsy, attention-deficit hyperactivity disorder (ADHD) in children, post-stroke depression or other depressive disorders. Children with attention deficit disorders

Mechanism Of Action:
Methylphenidate blocks dopamine uptake in central adrenergic neurons by blocking dopamine transport or carrier proteins. Methylphenidate acts at the brain stem arousal system and the cerebral cortex and causes increased sympathomimetic activity in the central nervous system. Alteration of serotonergic pathways via changes in dopamine transport may result.

News Articles on Methylphenidate

Shire Reports Tolerability and Clinical Effects Results of Daytrana(R ...  -  ‎Oct 30, 2009‎
Daytrana delivers medication directly through the skin into the bloodstream and is designed to release methylphenidate continuously while applied to the ... Reuters

The Ritalin study: Research raises concerns about safety of popular drug  -  ‎Nov 11, 2009‎
HOUSTON -- Most of us know it as Ritalin: the brand name for the drug methylphenidate. For a nearly a half-century, doctors have ... KVUE

Enforcement, regulation of Rx medicines lacking  -  ‎Nov 13, 2009‎
Vicodin, methamphetamine, Alprazolam, heroin and Methylphenidate. Addicts take as many as five of these very addictive and deadly drugs in combination. ... Colusa County Sun Herald

CONCERTA(R) in the Classroom: New Data on Attention in Children With ADHD  -  ‎Nov 4, 2009‎
Abuse of methylphenidate may lead to dependence. Tell your healthcare professional if you or your child has had problems with alcohol or drugs; ... Reuters

Researcher did not die of overdose, autopsy says  -  ‎Nov 13, 2009‎
The most serious include possession of marijuana with intent to distribute and possession of two prescription narcotics, the stimulant methylphenidate ... Baltimore Sun

Shire reports tolerability/clinical effects results of Daytrana from study in ...  -  ‎Nov 2, 2009‎
Daytrana delivers medication directly through the skin into the bloodstream and is designed to release methylphenidate continuously while applied to the ... PhysOrg.com

HealthFirst-Exercising your memory  -  ‎Nov 13, 2009‎
ADD MEDICATIONS: The most common drugs used to treat ADD are methylphenidate (Ritalin, Concerta, Daytrana), dextroamphetamine-amphetamine (Adderall), ... ABC12.com

ADHD Drugs Killed Their Son, Parents Say  -  ‎Oct 29, 2009‎
The Kansas couple says the drug makers never warned them that the drug combination could kill their son with methylphenidate toxicity. ... Courthouse News Service

Plummeting Adderall XR sales drag on Shire's quarter  -  ‎Nov 3, 2009‎
Furthermore, the group also anticipates further expanding its ADHD franchise next year with the launch of Daytrana (methylphenidate) for adolescents in the ... Pharma Times

In court Monday:  -  ‎Nov 4, 2009‎
MAURO, James V., 44, Boston; possession of cocaine, possession of Hydrocodone, possession of methylphenidate, possession of Xanax as a subsequent offense ... Cape Cod Times

Two 17 Year Old's Arrested In Monterey  -  ‎Oct 25, 2009‎
Ritalin (methylphenidate), Bates found, is similar in nature to Cocaine. It is the most common drug prescribed for Attention Deficit Disorder. ... UC Daily News

Off the Deep End: Prescription drug abuse is not a small problem  -  ‎Nov 11, 2009‎
Stimulants for ADHD and narcolepsy are also abused and include dextroamphetamine or Dexedrine, methylphenidate brand name Ritalin and Concerta, ... Lake County Record-Bee

Band-Aid Won't Stop Generic Bleeding at Johnson & Johnson  -  ‎Nov 11, 2009‎
Further patent risks to stateside sales include exclusivity challenges to the attention deficit disorder medicine Concerta (methylphenidate), ... BNET

Getting Kids Off Meds  -  ‎Nov 9, 2009‎
ADD MEDICATIONS: The most common drugs used to treat ADD are methylphenidate (Ritalin, Concerta, Daytrana), dextroamphetamine-amphetamine (Adderall), ... ABC7Chicago.com

Government Adviser Fired For Saying Alcohol Is More Dangerous Than Drugs  -  ‎Nov 1, 2009‎
Class B includes cannabis, amphetamine, codeine and methylphenidate ("Ritalin"). Finally, Class C includes GHB, ketamine, diazepam, flunitrazepam and most ... Huffington Post (blog)

EU Committee To Size Up Abbott, Solvay Cholesterol Drugs  -  ‎Oct 26, 2009‎
A recent example of a referral procedure was the EMEA's review of medicines containing methylphenidate, which treat attention-deficit hyperactivity disorder ... Wall Street Journal

Over And Out  -  ‎Nov 5, 2009‎
For a teen with ADD, the methylphenidate in the pill stimulates certain receptors in the brain and helps a diagnosed patient focus and stay calm. ... LongIslandPress.com

Before Prozac: The Troubled History of Mood Disorders in Psychiatry  -  ‎Nov 2, 2009‎
Methylphenidate, first synthesized by the Ciba chemist Leandro Panizzon, was named Ritalin after his wife, Marguerite (Rita). Shorter tells us that both she ... Am J Psychiatry (subscription)

Smart Pills: More Focus or Hocus Pocus?  -  ‎Oct 29, 2009‎
Examples include stimulants such as Ritalin (methylphenidate) and Adderall (amphetamine/dextroamphetamine combination)—the drugs used for children with ... HealthNewsDigest.com

Births and nubs of the news  -  ‎Oct 29, 2009‎
Possession of methylphenidate: Kalee J. Kicksey, YOB 1985, Bismarck, deferred sentence for three years with supervised probation, also possession of ... Bismarck Tribune

Woman charged after drug raid  -  ‎Oct 24, 2009‎
Johnson, who was free on bail at the time, was in possession of ecstasy, marijuana and methylphenidate, marketed as Ritalin, according to indictments ... The Keene Sentinel

Drugs database to make police work easier, faster  -  ‎Oct 21, 2009‎
It showed restricted drugs, such as morphine sulphate, Ritalin (methylphenidate) and codeine. "The main benefit to staff is a reduction in the time it can ... Timaru Herald

Promising early results for UCB's new products  -  ‎Oct 22, 2009‎
...declined due to the mild cough and cold season in the US earlier in the year, while net sales of Metadate(TM) CD (methylphenidate) increased. ... The FINANCIAL

“è?ªæ˜Žè?¯â€?真有效å?—?  -  ‎Nov 10, 2009‎
...å?ˆæ³•的精神兴奋剂包括苯哌啶醋酸甲酯(methylphenidate,å?³åˆ©ä»–æž—)ã€?安é?žä»–明(amphetamine)å?ŠèŽ«è¾¾é?žå°¼(modafinil)。æ?®æŠ¥é?“,在æŸ?些学校,1/4的学生都在æœ?用这些è?¯ç‰©ã€‚ ... 中青在线

大学生和白领æµ?行å?ƒçš„“è?ªæ˜Žè?¯â€?真有效?  -  ‎Nov 9, 2009‎
...å?ˆæ³•的精神兴奋剂包括苯哌啶醋酸甲酯(methylphenidate,å?³åˆ©ä»–林)ã€?安é?žä»–明(amphetamine)å?ŠèŽ«è¾¾é?žå°¼ï¼ˆmodafinil)。æ?®æŠ¥é?“,在æŸ?些学校,1/4的学生都在æœ?用这些 ... 人民网

è?ªæ˜Žè?¯è®©å¤§è„‘快速充电?  -  ‎Nov 4, 2009‎
...æ ¹æ?®ç¾Žå›½æ”¿åºœåœ¨2007å¹´æ?œé›†çš„资料,超过160万å??美国人在一年内曾因é?žåŒ»ç–—目的而使用需è¦?处方的兴奋剂,属于这个类别的å?ˆæ³•è?¯ç‰©åŒ…括派醋甲酯(methylphenidate,商å“?å??为 ... 中新网

ç’°ç?ƒç§‘學:è?°æ˜Žè—¥æƒ¹è³ªç–‘(組圖)  -  ‎Nov 6, 2009‎
...å?ˆæ³•的精神興奮劑包括苯呱啶醋酸甲酯(methylphenidate,å?³åˆ©ä»–æž—)ã€?安é?žä»–明(amphetamine)å?ŠèŽ«é?”é?žå°¼(modafinil)。據報導,在æŸ?些學校,1/4的學生都在æœ?用這些藥物。 ... 臺灣新浪網

Bổ ngá»­a vì... thuốc bổ óc  -  ‎Oct 20, 2009‎
Còn thuốc dextroamphetamine (biệt dược Dexedrine), methylphenidate (Ritalin) là thuốc kích thích hệ thần kinh được dùng chá»§ yếu trị bệnh gá»?i là “rối loạn ... Thanh Niên

Mehr Probleme mit der Psyche  -  ‎Oct 29, 2009‎
Häufig dafür missbrauchte Medikamente sind laut Krankenkasse beispielsweise Methylphenidate wie „Ritalin�, die eigentlich gegen Aufmerksamkeitsstörungen ... Derwesten.de

ריטלין וטיפול ב-ADHD ×?צל ילדי×?  -  ‎Nov 2, 2009‎
...ריטלין, הידוע בשמו הרפו×?×™ "methylphenidate", הינו תרופה ממשפחת החומרי×? המעוררי×? ופועל בעיקר על ידי חסימת החלבון המוביל לדופ×?מין שעל קרו×? ת×?×™ העצב במוח. ... BeOK פורטל בריאות ויופי

è?°æ˜Žè—¥å¹«å¤§è…¦å¿«é€Ÿå……電?  -  ‎Oct 28, 2009‎
...根據美國政府在2007å¹´è’?集的資料,超é?Ž160è?¬å??美國人在一年內曾因é?žé†«ç™‚目的而使用需è¦?處方的興奮劑,屬於這個類別的å?ˆæ³•藥物包括派醋甲酯(methylphenidate,商å“?å??為 ... 科學人雜誌 (需訂閲)

Rối loạn giấc ngá»§ ở ngưá»?i cao tuổi  -  ‎Oct 27, 2009‎
...dùng các chất gây hưng phấn trước khi ngá»§ như: trà, cà phê, nước ngá»?t có gas... hay má»™t số loại thuốc như Amphetamin, Methylphenidate. ... Báo Hoà Bình

Rapport intermédiaire - Premiers résultats prometteurs pour les nouveaux ...  -  ‎Oct 21, 2009‎
Les ventes nettes de Metadate(TM) CD (methylphenidate) ont par contre progressé. Les données concernant les prescriptions de Cimzia (certolizumab pegol) ... Euronext (persbericht)

“è?ªæ˜Žè?¯â€?争议:æ??高智商还是使人æˆ?瘾?  -  ‎Nov 5, 2009‎
...å?ˆæ³•的精神兴奋剂包括苯哌啶醋酸甲酯(methylphenidate,å?³åˆ©ä»–林)ã€?安é?žä»–明(amphetamine)å?ŠèŽ«è¾¾é?žå°¼ï¼ˆmodafinil)。æ?®æŠ¥é?“,在æŸ?些学校,1/4的学生都在æœ?用这些 ... 网易

Tussentijds rapport - Veelbelovende eerste resultaten voor nieuwe producten ...  -  ‎Oct 21, 2009‎
...van het zachte hoest- en verkoudhedenseizoen in de VS eerder dit jaar, terwijl de nettoverkoop van Metadate(TM) CD (methylphenidate) is gestegen. ... Analist.be (persbericht)

ADHD Drugs Are Used To Get High  -  30 Aug 2009
Stimulant medications, including Adderall and methylphenidate (Ritalin), have a high abuse potential. Due to the fact Adderall has a powerful effect of 24-7PressRelease.com (press release)

High-dose methylphenidate raises heart rate, BP in ADHD kids  -  ‎Aug 17, 2009‎
High-dose extended-release methylphenidate or Ritalin may increase heart rate and blood pressure in children with ADHD, researchers found. SmartBrief

More Teens Abuse ADHD Stimulants  -  ‎Aug 24, 2009‎
Methylphenidate-related calls decreased 30%, even though prescriptions increased 52% for that age group. And reports of exposure to methylphenidate fell MedPage Today

Study Links ADHD Drug Abuse With Increase In Prescriptions  -  ‎Aug 27, 2009‎
...being treated for the disorder turning to misusing the drugs. ADHD drugs are typically a mixture of the stimulates amphetamine salts and methylphenidate. AHN

Children taught to snort aspartame in kindergarten  -  ‎Aug 23, 2009‎
They have been using aspartame as a replacement for methylphenidate. ADD is rampant here. Students reportedly have been "thinking outside the box", The Spoof (satire)

EMEA makes adverse drug reaction research a priority  -  ‎Aug 11, 2009‎
The European Medicines Agency (EMEA) will look at the long-term effects in children and young adults of gold standard treatment methylphenidate for Pharmafocus

Possible association between stimulants used for ADHD and sudden ...  -  ‎Aug 28, 2009‎
Stimulant use was defined as the use of amphetamine, dextroamphetamine, methamphetamine, methylphenidate, or their derivatives immediately prior to death, Clinical Advisor

Generics versus Brands: Questions About Quality Control  -  ‎Aug 26, 2009‎
Legacy Pharmaceuticals for the Efudex brand of topical fluorouracil cream; and Noven Pharmaceuticals for its Daytrana transdermal methylphenidate patch. MedPage Today

Ask the Expert: Psychosomatic Medicine/Delirium  -  ‎Aug 28, 2009‎
...consider the use of psychostimulant agents (eg, methylphenidate, dextroamphetamine, or modafinil) or conventional dopamine agonists (eg, bromocriptine, Focus (subscription)

The Dangers of 99% Pure Caffeine  -  ‎Aug 26, 2009‎
For example, methylphenidate which is more commonly known as Ritalin is used for patients of ADHD or Attention Deficit Hyperactivity Disorder as well as Media Channel

EUROPE: New medical research priorities for 2010  -  ‎Aug 28, 2009‎
Researchers have been encouraged to propose reports on the adverse effects of the common ADHD treatment methylphenidate on children and youth, University World News

Wake Up and Smell the Coffee: Caffeine Has Its Benefits  -  ‎Aug 19, 2009‎
Caffeine has been shown to greatly intensify and prolong the effects of epinephrine-like drugs such as methamphetamine, amphetamine, and methylphenidate. Alternative Health Journal

Treatment of Narcolepsy Complicated by Psychotic Symptoms  -  ‎Aug 17, 2009‎
Narcolepsy with cataplexy was diagnosed, and treatment with central stimulants (methylphenidate) was initiated. Mr. A responded favorably to treatment, Psychosomatics (subscription)

Irritable bowel syndrome makes patients miserable  -  ‎Aug 7, 2009‎
Doctors prescribe methylphenidate or amphetamine for this strange illness. Modafinil is another drug that appears to be effective and safe. Alexandria Town Talk

Patient Safety: Getting the Name Wrong May be Fatal  -  ‎Aug 13, 2009‎
After receiving methadone instead of methylphenidate, a drug used to treat attention deficit disorders, an 8-year-old died, according to MedicineNet.com. ADVANCE

Targacept, Inc. Q2 2009 Earnings Call Transcript  -  ‎Aug 5, 2009‎
And the result indicated that our compound has the magnitude of affect comparable to what would be expected with stimulants, amphetamine and methylphenidate Seeking Alpha

Medication Implicated in Drug Abuse  -  ‎Aug 10, 2009‎
This year about six million children, roughly one child out of every eight, will take Ritalin or other forms of methylphenidate. The number of stimulants TransWorldNews (press release)

Tangled web left by online networking  -  ‎Aug 4, 2009‎
...threefold increase over this period in prescriptions for methylphenidate, the drug prescribed for attention-deficit hyperactivity disorder," she said. LLanelli Star

Adderall XR sales sink as Shire enthuses over new products  -  ‎Aug 6, 2009‎
Back to the figures, and sales of Shire's ADHD patch product Daytrana (methylphenidate), sales fell 34% to $14.9 million, while revenues from Elaprase Pharma Times

Israeli Researchers Explore Ritalin Alternative for ADHD  -  ‎Aug 6, 2009‎
Methylphenidate (MPH), or Ritalin, is a stimulant medication which has been used in the treatment of ADHD, or Attention Deficit Hyperactivity Disorder, Arutz Sheva

Psychiatric Aspects of HIV Spectrum Disease  -  ‎Aug 28, 2009‎
The combination of a short-acting form of methylphenidate with a long-acting form may be particularly useful. The short-acting form may be used to establish Focus (subscription)

å?‹éœ–生技ã€?美DURECTå?ˆä½œ 開發治療ADHD專利新藥  -  ‎Aug 18, 2009‎
...症狀會�續到�年,目�約有50%的ADHD �動兒接�甲麻黃素(Amphetamine)或中樞神經興奮劑(Methylphenidate)的治療,2008年全�ADHD治療用藥市場�模約為40億美金。 NOWnews

드림파마, ADHD 치료제 ë?¼ì?´ì„¼ìФ 계약  -  ‎Aug 9, 2009‎
...현재 한국내 ADHDì?˜ 대표ì ?ì?¸ 치료약물ì?€ methylphenidate 제제(한국얀센ì?˜ 콘서타 등)와 atomoxetine 제제(한국릴리ì?˜ 스트ë?¼í…Œë?¼) 등ì?´ 있다. 데일리팜

Accro aux smart drugs  -  ‎Aug 17, 2009‎
Favorise le calme et la concentration. concerta et pMS-Methylphenidate sont d'autres marques de méthylphénidate. Adderall XR (sels mixtes d'amphétamine à Châtelaine

בחירת הטיפול בהפרעת קשב  -  ‎Aug 27, 2009‎
...הטיפולי×? התרופתיי×? השכיחי×? ביותר מכילי×? חומר ממריץ (סטימולנט) בש×? methylphenidate, שהו×? החומר ×”×?קטיבי בתרופות המוכרות ב×?רץ בש×? ריטלין וקונצרטה. דוקטורס

9월부터 í??ê²½ 후 호르몬제 등 약제 5항목 급여신설  -  ‎Aug 27, 2009‎
...ì?˜í•œ 중ì¦?ì?˜ 불안장애를 ë?™ë°˜í•´ Methylphenidate HCl 서방형 경구제(품명: 콘서타OROS서방정, 메타ë?°ì?´íЏCD서방캡ìŠ?)를 사용할 수 없는 경우 요양급여가 ì?¸ì •ë?œë‹¤. 메디포뉴스

9월부터 '헵세ë?¼Â·ë°”ë?¼í?¬ë£¨ë“œ' 급여기준 확대  -  ‎Aug 27, 2009‎
...(품명 : 스트ë?¼í…Œë?¼ 캡ìŠ?)ì?˜ 경우 중ì¦?ì?˜ 불안장애를 ë?™ë°˜í•˜ì—¬ Methylphenidate HCl 서방형 경구제(품명 : 콘서타OROS서방정, 메타ë?°ì?´íЏCD서방캡ìŠ?)를 사용할 수 없는 메디게이트뉴스

Brand Names/Synonyms:
Methylphenidate is also known by the following brand names and/or synonyms:
4311/B Ciba; C 4311; CHEMBANK1663; Calocain; Centedein; Centedrin; Centedrine; Centredin; Concerta; Dea No. 1724; Focalin; Focalin Xr; HSDB 3126; METHYLPHEN; Meridil; Metadate; Metadate Cd; Metadate Er; Methyl Phenidyl Acetate; Methylin; Methylin Er; Methylofenidan; Methylphenidan; Methylphenidate; Methylphenidate Hcl; Methylphenidate Hydrochloride; Methylphenidatum [Inn-Latin]; Methylphenidylacetate Hydrochloride; Methypatch; Metilfenidat Hydrochloride; Metilfenidato [Inn-Spanish]; Metilfenidato [Italian]; Phenidylate; Plimasine; Pms-Methylphenidate; Riphenidate; Ritalin; Ritalin Hydrochloride; Ritalin La; Ritalin Sr; Ritalin-Sr; Ritaline; Ritcher Works

Drug Category:
Methylphenidate is categorized under the following by the FDA: Adrenergic Agents; Dopamine Agents; Central Nervous System Agents; Anorexigenic Agents; Stimulants; ATC:N06BA04

Dosage Forms:
Tablets, SR tablets

Absorption:
readily absorbed in a biphasic manner. It reaches peak absorption at approximately two hours for the first phase and five hours for the second phase. bioavailability is low (approx. 30%)

Interactions:
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Chemical IUPAC Name:
methyl2-phenyl-2-(2-piperidyl)ethanoate





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