Mevacor

This page contains recent news articles, when available, and an overview of Mevacor but does not offer medical advice. You should contact your physician with regard to any health issues or concerns.


Overview:

Mevacor
(when available)

Pharmacology and use:
Lovastatin, an antilipemic agent produced by fermentation of Aspergillus terreus, is the first of a class of lipid-lowering agents known as the HMG-CoA reductase inhibitors. Lovastatin is used to treat hypercholesterolemia, to slow coronary atherosclerosis, and to prevent myocardial infarction and stroke. Lovastatin, like simvastin and unlike pravastatin, is a prodrug, concentrating active drug in the liver during first-pass circulation. For management as an adjunct to diet to reduce elevated total-C, LDL-C, apo B, and TG levels in patients with primary hypercholesterolemia and mixed dyslipidemia; For primary prevention of coronary heart disease

Mechanism Of Action:
Lovastatin is a lactone that is readily hydrolyzed in vivo to the corresponding b-hydroxyacid, a potent inhibitor of HMG-CoA reductase, the enzyme that catalyzes the conversion of HMG-CoA to mevalonate. The conversion of HMG-CoA to mevalonate is an early step in the biosynthetic pathway for cholesterol.

News Articles on Lovastatin

Statins Don't Curb Colorectal Cancer Risk  -  ‎Dec 29, 2009‎
Although laboratory studies have indicated that statins -- which include drugs such as Lipitor, Crestor, Pravachol, and Mevacor -- can inhibit cancer cell ... ABC News

The Taming of the Heart Attack  -  ‎Jan 1, 2010‎
The first one, lovastatin (Mevacor), didn't come on the market until 1987," Nissen recalled. "It wasn't a very good statin, but it was a lot better than ... MedPage Today

The Top 10 Medical Advances of the Decade  -  ‎Dec 18, 2009‎
Moreover, drugs that didn't exist 25 years ago -- chiefly statins like simvastatin, Lipitor, mevacor, and Crestor -- are now routinely used to slow the ... MedPage Today

FDA Hands-Off On St. John's wort Cataract Connections (Part 3)  -  ‎Dec 14, 2009‎
...because the active pharmaceutical agent lovastatin, is the same ingredient in the prescription drug, Mevacor, marketed for treating high cholesterol. ... InjuryBoard.com (blog)

Las estatinas no limitan el riesgo de cáncer colorrectal  -  ‎Jan 1, 2010‎
Aunque estudios de laboratorio indicaban que las estatinas -que incluyen fármacos como Lipitor, Crestor, Pravachol y Mevacor- pueden inhibir la ... Público

Para algunos, una hierba sería la alternativa a las estatinas  -  ‎Dec 29, 2009‎
...a la estatina llamados monacolinas, incluida la monacolina K, que es estructuralmente idéntica a la lovastatina (Mevacor) para bajar el colesterol. ... Público

Are US consumers subsidizing prescription drug costs in other countries?  -  ‎Nov 12, 2009‎
Ever wonder why the same Mevacor for which we pay $200 (per 100 pills) cost's a mere $8-10 (per 100 pills) in Mexico? Think that's a exception....think ... Examiner.com

Red yeast rice: A natural approach to high cholesterol  -  ‎Oct 26, 2009‎
...that's used in traditional Chinese medicine, contains monacolin K, the same ingredient as in the prescription cholesterol drug lovastatin (Mevacor). ... Chicago Tribune

Cholesterol-Lowering Statin May Diminish Flu Deaths  -  ‎Oct 30, 2009‎
...were taking statins containing Crestor, Lescol, Lipitor, Mevacor, Pravachol, and Zocor, are less likely to die than those who weren't taking the drugs. ... TopNews New Zealand

Cholesterol drug sales set to double  -  ‎Nov 6, 2009‎
Other than Lipitor, statins also include other top grossers like AstraZeneca's Crestor, Merck's Zocor and Mevacor, amongst others. Daily News & Analysis

스타틴 복용, ë?…ê°? ì?¸í•œ 사ë§?률 50% ê°?소해  -  ‎Oct 29, 2009‎
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Merck's Mevacor Requires Prescription, FDA Panel Says  -  Jan 14, 2005
By Kerry Dooley. Jan. 14 (Bloomberg) -- Merck & Co. and Johnson & Johnson shouldn't be allowed to sell their Mevacor cholesterol drug without a doctor's ... Bloomberg

Cholesterol buster Mevacor again seeks OTC approval  -  Dec 9, 2007
By Rita Rubin, USA TODAY. A Food and Drug Administration advisory panel on Thursday will consider whether consumers should be able to buy a ... USA Today

FDA rejects over-the-counter statin Mevacor  -  Jan 25, 2008
WHITEHOUSE STATION, NJ - Merck & Co. on Friday said the Food and Drug Administration rejected its application to market an over-the-counter cholesterol drug ... msnbc.com

FDA Staff Notes Mevacor Criteria Confusion  -  Jan 12, 2005
Staff researchers at the Food and Drug Administration raised questions Wednesday about how well consumers understand guidelines for Mevacor, a cholesterol ... TheStreet.com - TheStreet.com (subscription)

Panel: Keep Mevacor off shelves - Merck wants its statin to be over...  -  Dec 14, 2007
A panel of advisers to the Food and Drug Administration yesterday rejected a request by Merck & Co. Inc. to sell its cholesterol-lowering statin drug ... $2.95 - Philadelphia Inquirer - NewsBank

… enters OTC marketing rights agreement for Merck's Mevacor  -  Nov 26, 2007
The new drug application for over-the-counter Mevacor will be reviewed by the Food and Drug Administration on Dec. 13. US-listed shares of GlaxoSmithKline ... Forbes

Glaxo to buy US rights to Merck's Mevacor  -  Nov 27, 2007
By Bloomberg News | November 27, 2007. GlaxoSmithKline PLC, Europe's largest drug maker, agreed to buy the rights to sell Merck & Co.'s Mevacor ... Boston Globe

FDA Panel Nixes OTC Cholesterol Drug Sales  -  Jan 17, 2005
The safety of Mevacor (search) is well-established, but advisers worried that the wrong people might take it if it sat on open drugstore shelves, ... FOXNews

Vytorin On Trial  -  Mar 21, 2008
Mevacor and other statins were developed from genetic insights gleaned from patients ... In 1994 and 1995, studies of Merck's Zocor, a Mevacor replacement, ... Forbes

Mevacor Rejected for Over-The-Counter Use  -  Jan 19, 2005
Merck's prescription drug Mevacor, prescribed for lowering cholesterol, was rejected on January 14, 2005. Find out why the Food and Drug Administration ... Buzzle

Pharmacies offer 'behind the counter' service  -  Feb 7, 2005
The panel voted 20-3 against Merck's plan to switch Mevacor, a prescription ... "It's an option we ought to look at," Ganley said after the Mevacor meeting. ... USA Today

Lipitor pills can be safely split  -  Mar 20, 2006
Researchers at Veterans Affairs and Kaiser Permanente in California determined that splitting atorvastatin (Lipitor), lovastatin (Mevacor) and simvastatin ... Los Angeles Times

Article: Will Mevacor be next? - The Record (Bergen County, NJ) | …  -  Jan 12, 2005
Will Mevacor be next? ... find The Record (Bergen County, NJ) articles. LEWIS KRAUSKOPF, STAFF WRITER The Record (Bergen County, NJ) 01-12-2005 Will Mevacor ... Pay-Per-View - The Record - HighBeam Research

FDA to Merck: Mevacor OTC not approvable  -  Jan 28, 2008
The FDA needs to see additional data from Merck before approving an OTC version of the drugmaker's cholesterol-lowering drug Mevacor (lovastatin). ... Medical Marketing & Media - Medical Marketing and Media

Article: Stick to script with Mevacor, feds say Over-the-counter...  -  Jan 15, 2005
Stick to script with Mevacor, feds say Over-the-counter sales of cholesterol drug discouraged ... find Chicago Sun-Times articles. Pay-Per-View - Chicago Sun-Times - HighBeam Research

Cholesterol Drugs May Avert Cataracts  -  Jun 20, 2006
Those who took Pravachol, Lescol, and Mevacor had a combined 33% lower risk. Risk for other kinds of age-related cataracts did not go down with the use of ... WebMD

Advisory Committee Rejects OTC Mevacor  -  Dec 17, 2007
A joint FDA Nonprescription Drugs and Endocrinologic and Metabolic Advisory Committee voted 10–2 with one abstention recommending the FDA not approve ... FDA news - FDA news (subscription)

… Merck & Co/J&J's application for OTC Mevacor.(Food and...  -  Jan 24, 2005
Although the panel's recommendation on Mevacor, one of the oldest statins ... The approval of Mevacor for non-prescription sales would have marked the first ... Free with registration - Pharma Marketletter - AccessMyLibrary.com

FDA panels vote against Mevacor Daily OTC switch.  -  Jan 14, 2008
FDA panels vote against Mevacor Daily OTC switch. SILVER SPRING, Md. -- It's safe. It's effective. But again it was the lack of appropriate self-selection ... $9.94 - Drug Store News - Alacra Store

Mevacor No Rx  -  Oct 30, 2007
...and Behavior study of chemicals requires intimate knowledge Mevacor No Rx cell biology and biochemistry increasing, the Mevacor No Rx of medication is a ... Sokwanele

DEAR PHARMACIST, Weight-loss stimulants can be a danger  -  May 2, 2006
Yes, it's safer than statins - popular ones are Lipitor, Zocor, Pravachol, Lescol, Advicor, Crestor and Mevacor. Statins reduce cholesterol well, ... Pay-Per-View - Newsday - ProQuest Archiver

Why Merck Lost Its 3rd Bid to Sell Mevacor Over the Counter  -  Feb 4, 2008
...(NaturalNews) An expert panel working with the FDA recently voted 10 to 2 against approving Merck's statin drug Mevacor for over-the-counter (OTC) sales. ... Natural News.com

Pfizer's Drug Problem: Lipitor  -  Jun 14, 2007
Generic copies of Mevacor, an older Merck drug, control 8%. Brand-name drugs are taking their toll, too. Schering-Plough's (SGP - commentary - Cramer's ... TheStreet.com - TheStreet.com (subscription)

Mevacor users will still need a prescription | Article from The...  -  Jan 15, 2005
Mevacor users will still need a prescription ... find The Record (Bergen County, NJ) articles. LEWIS KRAUSKOPF, STAFF WRITER The Record (Bergen County, ... Pay-Per-View - The Record - HighBeam Research

Cholesterol drugs linked to muscle pain  -  Aug 10, 2008
A: Statin-type cholesterol-lowering drugs such as Crestor (rosuvastatin), Lipitor (atorvastatin), Mevacor (lovastatin) and Zocor (simvastatin) are linked to ... Seattle Times

FDA Panel Rejects Merck Statin Mevacor  -  Dec 14, 2007
An FDA advisorypanel on Thursday voted 10-2 against recommending that Merck'scholesterol drug Mevacor be granted over-the-counter status, the Philadelphia ... emaxhealth.com

Atlanta health, diet and fitness news | ajc.com  -  Jan 13, 2005
In its petition to the agency, Merck said Mevacor has a low risk of muscle ... Supporters of the proposal say approval of OTC Mevacor would help people who ... Atlanta Journal Constitution

Grapefruit Might Lower Cholesterol .  -  Mar 14, 2006
Grapefruit can interact with dozens of drugs, in cluding some very popular cholesterol-lowering medications lipitor Mevacor and Zocor). ... Lakeland Ledger - Google News Archive

Cheap Mevacor Online  -  May 30, 2007
...outlay pharmaceutical companies may do a number of things:[2] * Carefully research the demand for their potential new medicines typically only one Cheap ... Sokwanele

Do cholesterol medicines really work?  -  Jul 29, 2008
...(Statins are: Zocor, Pravachol, Crestor, Lescol, Mevacor and Lipitor.) Muscle pain occurs in one in 1000 users. Muscle damage occurs in much fewer. ... Roanoke Times

No RX Mevacor  -  May 29, 2007
...describes the effect of the No RX Mevacor on the legal jurisdiction. Medications are typically produced by pharmaceutical companies No RX Mevacor No RX ... Sokwanele

Press Release: Mevacor's Future Undecided as an Over-The-Counter …  -  Feb 9, 2006
Mevacor has twice been rejected by the FDA for OTC status. High cholesterol, for which statins are prescribed, is thought to be a condition that may be too ... Pay-Per-View - PR Newswire - HighBeam Research

Article: HEART DRUG MAY GET OTC SALES APPROVAL.(News) - The …  -  Jan 14, 2005
Allowing over-the-counter sales for Mevacor would put a new sort of medication on ... ... Article: FDA approves new prescription drug Mevacor, shown to ... ... Pay-Per-View - Cincinnati Post - HighBeam Research

Mevacor from Canadian Pharmacy  -  Jul 28, 2007
...is practiced Mevacor pharmacologists. Subdisciplines include clinical pharmacology (the medical field of medication on Mevacor and nervous system ... Sokwanele

PUT CHOLESTEROL IN PERSPECTIVE  -  Mar 12, 2008
The medicines that gave you muscle pain were probably the statin drugs - Zocor, Pravachol, Crestor, Lescol, Lipitor and Mevacor. They are the most-often- ... Pay-Per-View - South Florida Sun - Sentinel - ProQuest Archiver

Cholesterol drugs all alike, new research says  -  Apr 26, 2005
In addition to Lipitor and Lescol, researchers looked at Zocor, Mevacor and ... Patients taking Mevacor had a slightly higher risk of having a heart attack, ... Globe and Mail

Mevacor's Future Undecided as an Over-The-Counter Drug.  -  Feb 9, 2006
Mevacor has twice been rejected by the FDA for OTC status. High cholesterol, for which statins are prescribed, is thought to be a condition that may be too ... $4.95 - PR Newswire - ECNext

Mevacor.(Drug overview)  -  Jan 22, 2007
Mevacor is used, along with diet, to lower cholesterol levels in people with primary hypercholesterolemia (too much cholesterol in the bloodstream). ... Free with registration - PDR Family Guide to Prescription Drugs - AccessMyLibrary.com

Article: FDA TO WEIGH STATINS SALES OVER THE COUNTER.(News) - …  -  Jan 13, 2005
...s request to sell its 20-milligram Mevacor pill over-the-counter. ... Doctors generally regard 20-mg Mevacor -- the usual recommended starting dose -- as ... Pay-Per-View - Cincinnati Post - HighBeam Research

Merck Receives Another Not-Approvable Letter for OTC Statin Mevacor  -  Jan 31, 2008
Merck's attempt to bring an OTC statin to the market suffered another blow as the FDA issued a not-approvable letter for the company's switch application ... FDA news - FDA news (subscription)

Joe and Teresa  -  Mar 14, 2006
...dozens of drugs, including some very popular cholesterollowering medications lipitor Mevacor and Zocor). Because of biological variability, ... Times-News - Google News Archive

Purchase Mevacor  -  Oct 29, 2007
To protect the consumer and prevent abuse, many governments regulate the manufacture, sale, and administration of medication. ... Sokwanele

Fresh onion juice eases kitchen burns, prevents blisters  -  Jul 24, 2008
But I heard that in 2007, the Food and Drug Administration restricted sales of red yeast rice if it contained lovastatin, the ingredient in Mevacor. ... Youngstown Vindicator

Purchase Mevacor Online  -  Aug 24, 2007
...abuse, many governments regulate Purchase Mevacor Online manufacture, sale, and administration of medication. In the United States Pharmacopoeia. ... Sokwanele

Colonoscopy better for colon exam .  -  Sep 6, 2006
The proper response to the orig inal question was that red yeast rice contains a natural form of Mevacor, which is a statin drug. ... Rock Hill Herald - Google News Archive

Panel Makes Recommendation Against Mevacor | Article from AP Online |...  -  Jan 15, 2005
Panel Makes Recommendation Against Mevacor ... find AP Online articles. LAURA MECKLER, Associated Press Writer AP Online 01-15-2005 Dateline: BETHESDA, ... Pay-Per-View - AP Online - HighBeam Research

FDA issues "non-approvable" letter for Merck & Co's OTC Mevacor.  -  Feb 11, 2008
...for an over-the-counter formulation of drug major Merck & Co's cholesterol-lowerer Mevacor (lovastatin) 20mg, which has been under review since 1999. Free with registration - Pharma Marketletter - AccessMyLibrary.com

Breaking the vicious cycle  -  Oct 24, 2006
...(Glucophage) for diabetes, fluoxetine (Prozac) for depression, metoprolol (Lopressor) for high blood pressure and lovastain (Mevacor) for cholesterol. ... $2.95 - Ocala Star-Banner - NewsBank

FDA may loosen sales of Merck's Mevacor  -  Oct 23, 2007
By : Agencies. WASHINGTON (AP) - Drug maker Merck will attempt to convince government health advisers in December that its cholesterol-lowering pill Mevacor ... ABCmoney.co.uk

Panel Makes Recommendation Against Mevacor | Article from AP Online |...  -  Jan 16, 2005
Panel Makes Recommendation Against Mevacor ... find AP Online articles. LAURA MECKLER, Associated Press Writer AP Online 01-16-2005 Dateline: BETHESDA, ... Pay-Per-View - AP Online - HighBeam Research

FDA Bans Selling Mevacor Over-the-Counter | Article from AP Online | ...  -  Jan 15, 2005
FDA Bans Selling Mevacor Over-the-Counter ... find AP Online articles. LAURA MECKLER, Associated Press Writer AP Online 01-15-2005 Dateline: BETHESDA, ... Pay-Per-View - AP Online - HighBeam Research

Statins less effective for women post-heart attack  -  Jan 30, 2007
The statins included in the study were atorvastatin (Lipitor), pravastatin (Pravachol), simvastatin (Zocor), lovastatin (Mevacor), rosuvastatin (Crestor) ... CTV.ca

Article: Advisers to FDA restrict over-the-counter sales of cholestero...  -  Jan 15, 2005
The two pharmaceutical companies that want to sell the drug, Mevacor, ... He voted against over-the-counter sales of Mevacor, one of a class of "statin" ... Pay-Per-View - Washington Times - HighBeam Research

Article: FDA Bans Selling Mevacor Over-The-Counter - AP Online | …  -  Jan 15, 2005
FDA Bans Selling Mevacor Over-The-Counter ... find AP Online articles. LAURA MECKLER, Associated Press Writer AP Online 01-15-2005 Dateline: BETHESDA, ... Pay-Per-View - AP Online - HighBeam Research

Health Canada issues advisory over statins  -  Jul 14, 2005
The medications, which include Lipitor (atorvastatin), Zocor (simvastatin), Mevacor (lovastatin), Lescol and Lescol XL (fluvastatin), ... CTV.ca

Article: FDA nixes OTC status for Mevacor.(RX/Government)(Brief...  -  Jan 31, 2005
FDA nixes OTC status for Mevacor.(RX/Government)(Brief Article) ... find Chain Drug Review articles. BETHESDA, Md. -- An advisory panel to the Food and Drug ... Pay-Per-View - Chain Drug Review - HighBeam Research

Use exercise to free a locked shoulder  -  Apr 28, 2007
My friend takes Mevacor. We wonder if combining the two medicines would bring our ... However, the combination of Mevacor and Lopid is not a good one. ... Chattanooga Times Free Press

Advisers to FDA restrict Mevacor; Want to limit to prescriptions.( …  -  Jan 15, 2005
Advisers to FDA restrict Mevacor; Want to limit to prescriptions.(BUSINESS) ... find The Washington Times articles. Byline: Tom Ramstack, THE WASHINGTON ... Pay-Per-View - Washington Times - HighBeam Research

Switches are now harder to come by.  -  Jan 2, 2006
In January 2005 an FDA panel voted against recommending the over-the-counter sale of the drug Mevacor (the brand name of lovastatin), asserting that Merck ... $9.94 - Chain Drug Review - Alacra Store

… ; Report: Cholesterol drugs still poised for OTC switch despite...  -  Feb 27, 2005
..."Everyone will be looking at the FDA's final judgment on Mevacor very carefully to ... These are the areas where Mevacor fell short, the advisory committee ... Pay-Per-View - Medical Letter on the CDC & FDA - Factiva, from Dow Jones

FDA Weighs Over-Counter Cholesterol Drug  -  Jan 19, 2008
But when Merck tested if consumers could judge who was a proper Mevacor candidate, only 20 percent answered all the questions completely correctly _ 50 ... FOXNews

March of Dimes; Group opposes over-the-counter status for Mevacor  -  Feb 16, 2005
2005 FEB 16 - (NewsRx.com & NewsRx.net) -- The March of Dimes opposes over-the-counter (OTC) status for Mevacor (lovastatin), a Pregnancy Category X drug ... Pay-Per-View - Biotech Week - Factiva, from Dow Jones

UNRESTRICTED SALE OF MEVACOR OPPOSED  -  Jan 15, 2005
Federal health advisers recommended against over-the-counter sales of a cholesterol drug Friday, saying that patients need medical guidance for treatment of ... $2.95 - Beacon Journal - NewsBank

PEOPLE'S PHARMACY  -  Mar 23, 2007
My pharmacist says I must not eat grapefruit while I am taking lovastatin (a generic for Mevacor). Would it be safe if I eat my grapefruit at breakfast and ... Pay-Per-View - The Sun - ProQuest Archiver

Pungent Spice Cures Scalp Of Psoriasis .  -  May 18, 2005
I take for blood pressure and Mevacor to con trol cholesterol and triglycerides. ... Could Mevacor being doing this? If so, are there any less expensive ... Lakeland Ledger - Google News Archive

A MIRACLE SOLUTION FOR FLAKY SCALP? ; PEOPLE'S PHARMACY  -  Jun 21, 2007
Cholesterol-lowering drugs like atorvastatin (Lipitor), lovastatin (Mevacor) and simvastatin (Zocor) are all affected by grapefruit. ... Pay-Per-View - The Sun - ProQuest Archiver

… Exclusive US OTC Marketing Rights to MEVACOR(R) (lovastatin) from ...  -  Nov 26, 2007
GlaxoSmithKline Obtains Exclusive US OTC Marketing Rights to MEVACOR(R) (lovastatin) from Merck & Co., Inc. from PR Newswire. Pay-Per-View - PR Newswire - HighBeam Research

Physically active man tells Dr. Gott a daily oatmeal  -  Sep 8, 2005
He prescribed Mevacor. I took the medicine for three or four days and did not feel about the effect it was having on me, so I . ... Spokesman-Review - Google News Archive

More cholesterol-lowering drugs on the market than statins .  -  Oct 21, 2005
RE Answer: The statin medi cines — Mevacor, Zocor, Pravachol, Lipitor and Crestor— are the most potent choles terol-lowering medicines avail able. ... Herald-Journal - Google News Archive

HOW TO PREVENT FAINTING SPELL  -  Aug 15, 2007
Statin drugs that stay a relatively short time in the blood are taken before going to bed to stop the liver's nighttime cholesterol output - Mevacor, ... Pay-Per-View - South Florida Sun - Sentinel - ProQuest Archiver

GRAEDONS | People's Herbal Pharmacy Indian spice tumeric can help …  -  May 19, 2005
I take diltiazem for blood pressure and Mevacor to control cholesterol and ... Could Mevacor be doing this? If so, are there any less expensive alternatives ... Youngstown Vindicator

Lipitor or Mevacor?  -  May 12, 2007
Presently take Lipitor for Chlolestoral, understand taking Lipitor prevents one from eating Grapefruit, as it tends to increase and retain lipitor's ... HealthCentral.com

Warning letters.  -  Aug 20, 2007
Lovastatin is the active pharmaceutical ingredient in Mevacor, a drug approved by ... Mevacor was approved Aug. 31, 1987 and neither lovastatin as a single ... Free with registration - Food Chemical News - AccessMyLibrary.com

Statins.(Cardiology Advisor 2006)  -  Nov 1, 2006
They include atorvastatin (Lipitor), fluvastatin (Lescol), lovastatin (Mevacor), pravastatin (Pravachol), rosuvastatin (Crestor), and simvastatin (Zocor). ... $4.95 - Clinical Reference Systems - ECNext

Statins Could Still Go OTC, Despite Recent Setback  -  Feb 21, 2005
Mevacor, which lost patent protection in 2001, has in many ways served as the guinea pig for switches of nonlifestyle drugs. Given the FDA's continued ... ICIS

STATINS: A risk to your baby? ; With cholesterol drug possibly going...  -  Jan 13, 2005
One of those babies, as well as a baby whose mother took Mevacor, ... Over-the-counter Mevacor would widen access to cholesterol treatment, thereby helping ... Pay-Per-View - USA TODAY - ProQuest Archiver

FDA Safety Labeling Changes: Novantrone, Mevacor, Nitro-Dur  -  Jul 6, 2005
July 6, 2005 — The US Food and Drug Administration (FDA) approved in April revisions to safety labeling to advise that use of mitoxantrone is associated ... Medscape

FDA questions Mevacor instructions  -  Dec 11, 2007
...by The Star-Ledger Business Desk. Merck has not provided evidence that consumers can adequately understand the instructions on a proposed over-the-counter ... nj.com

Over-the-counter Sales Of Mevacor Rejected .  -  Dec 14, 2007
...thecounter sales of Mevacor, the granddaddy of the famed cholesterol-lowering drugs. Too many of the wrong people would use the drug if it no longer ... Tuscaloosa News - Google News Archive

FDA Safety Labeling Changes: Hectorol, Mevacor, Pulmicort Respules  -  Sep 28, 2005
Sept. 28, 2005 ( updated Oct. 6, 2005) -- The US Food and Drug Administration (FDA) approved safety labeling revisions in June to advise that ... Medscape

… signs agreement for OTC form of Mevacor.(OT-Cs)(GlaxoSmithKline …  -  Dec 17, 2007
GlaxoSmithKline PLC (GSK) has signed a deal with Merck & Co. to sell a nonprescription version of the latter's cholesterol drug Mevacor. ... Free with registration - Chain Drug Review - AccessMyLibrary.com

Restrictions urged for Mevacor sales  -  Jan 15, 2005
The safety of Mevacor is wellestablished, but advisers worried that the wrong people might take it if sat on open drugstore shelves, particularly after a ... Tri City Herald - Google News Archive

LOW CHOLESTEROL AFFECTS CONCENTRATION  -  Feb 28, 2005
...barley, eggplant, okra, almonds, soy and cholesterol-lowering margarine in a combination diet lower cholesterol nearly as well as lovastatin (Mevacor). ... $3.50 - Press Telegram - NewsBank

Reaching 'ideal' cholesterol: Try first without medicines  -  Nov 5, 2007
Statins — Mevacor, Lipitor, Zocor, Lescol, Pravachol and Crestor — are the most powerful cholesterol-lowering drugs. They can cause muscle pain and can ... SouthCoastToday.com - SouthCoastToday.com

… Still Poised for OTC Switch Despite Mevacor Setback. - PR Newswire...  -  Jan 27, 2005
Cholesterol Drugs Still Poised for OTC Switch Despite Mevacor Setback. from PR Newswire. Highbeam Research – FREE Trial. Pay-Per-View - PR Newswire - HighBeam Research

Drugs For ADD Turn Teenager Testy  -  Mar 21, 2005
A. Although statin-type drugs such as lovastatin (Mevacor), simvastatin (Zocor) and atorvastatin (Lipitor) are powerful tools for lowering cholesterol, ... HealthCentral.com

Cholesterol Drop .  -  Dec 13, 2007
Another is Mevacor, a product Merck hopes to be gin selling over the counter. However, federal health officials worry that some con sumers can't be trusted ... Lakeland Ledger - Google News Archive

La Conchita Mourns; Mevacor Might Go Over-the-Counter.  -  Jan 13, 2005
RICK SANCHEZ, CNN ANCHOR: We are halfway through the hour, exactly at the 30 minute point. I'm Rick Sanchez. Why you looking at me like that? ... Free with registration - America's Intelligence Wire - AccessMyLibrary.com

… ; Report: Cholesterol drugs still poised for OTC switch despite...  -  Feb 25, 2005
..."Everyone will be looking at the FDA's final judgment on Mevacor very carefully to ... These are the areas where Mevacor fell short, the advisory committee ... Pay-Per-View - Drug Week - Factiva, from Dow Jones

Cholesterol Drugs Still Poised for OTC Switch Despite Mevacor Setback.  -  Jan 27, 2005
LITTLE FALLS, NJ, Jan. 27 /PRNewswire/ -- In its application to switch its cholesterol-lowering drug Mevacor from prescription to over-the-counter status, ... $4.95 - PR Newswire - ECNext

Article: FDA Panel Nixes OTC Cholesterol Drug Sales - AP Online | …  -  Jan 15, 2005
The safety of Mevacor is well-established, but advisers worried that the wrong people might take ... The cholesterol drug Mevacor has long been available by ... Pay-Per-View - AP Online - HighBeam Research

Article: FDA Weighs OTC Sales for Cholesterol Drug - AP Online | …  -  Jan 13, 2005
The cholesterol drug Mevacor has long been available by prescription. ... Allowing over-the-counter sales for Mevacor would put a new sort of medication on ... Pay-Per-View - AP Online - HighBeam Research

OTC statins vetoed again by FDA panels  -  Jan 31, 2005
...jointly 20-3 against a proposal by Merck & Co. and Johnson & Johnson to sell 20 mg tablets of Mevacor directly to consumers without a prescription. ... American Medical News

DEAR DR. DONOHUE: I .  -  Aug 11, 2006
Statin drugs Zocor, Lipi— tor, Crestor, Pravachol and Mevacor are the most-- powerful cholesterol-lowering drugs available. They stop the . Bryan Times - Google News Archive

All Questions Relating To "medical advice"  -  Jul 22, 2008
...would the sensation of like scratches beneath the skin also be a side effect of mevacor? Has anyone with fibromyalgia found a way to lower their cholesterol ... HealthCentral.com

Mevacor OTC switch.(Noted) | Article from Pharmaceutical Processing |...  -  Mar 1, 2005
Mevacor OTC switch.(Noted) ... find Pharmaceutical Processing articles. Mevacor OTC switch: FDA appears to have issued a "not approvable" letter for OTC ... Pay-Per-View - Pharmaceutical Processing - HighBeam Research

Anti-obesity drug gets first shot at OTC  -  Dec 15, 2005
This past January, an FDA advisory panel voted 20-3 against recommending approval of OTC Mevacor, a cholesterol-lowering drug. Maker Merck failed to show ... wtopnews.com

… Drug Reaction; Group opposes over-the-counter status for Mevacor  -  Feb 19, 2005
2005 FEB 19 - (NewsRx.com & NewsRx.net) -- The March of Dimes opposes over-the-counter (OTC) status for Mevacor (lovastatin), a Pregnancy Category X drug ... Pay-Per-View - Obesity, Fitness & Wellness Week - Factiva, from Dow Jones

… Drug Reaction; Group opposes over-the-counter status for Mevacor  -  Feb 14, 2005
2005 FEB 14 - (NewsRx.com & NewsRx.net) -- The March of Dimes opposes over-the-counter (OTC) status for Mevacor (lovastatin), a Pregnancy Category X drug ... Pay-Per-View - OBGYN & Reproduction Week - Factiva, from Dow Jones

Merck pushes again for OTC statin | Article from The Record (Bergen …  -  Dec 14, 2007
The worry: That too many of the wrong people would use OTC Mevacor, ... He acknowledged that letting Mevacor move over the counter would mark a big shift in ... Pay-Per-View - The Record - HighBeam Research

Brand Names/Synonyms:
Mevacor is also known by the following brand names and/or synonyms6alpha-Methylcompactin; Altocor; Altoprev; Artein; Belvas; Cholestra; Closterol; Colevix; Compactin; HSDB 6534; Hipolip; Hipovastin; Lestatin; Lipdip; Lipivas; Lipofren; Lovalip; Lovalord; Lovastatin; Lovastatin [Usan:Ban:Inn]; Lovastatina [Spanish]; Lovastatine [French]; Lovastatinum [Latin]; Lovasterol; Lovastin; Lozutin; MK 803; MK-803; ML-530B; MSD 803; Mevacor; Mevastatin; Mevinacor; Mevinolin; Mevlor; Monacolin K; Nergadan; Paschol; Pravastatin; Rodatin; Rovacor; Sivlor; Taucor; Tecnolip; Teroltrat

Drug Category:
Mevacor is categorized under the following by the FDA: Antineoplastic Agents; Anticholesteremic Agents; HMG-CoA Reductase Inhibitors; ATC:C10AA02

Dosage Forms:
Tablet

Absorption:
30%

Interactions:
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Chemical IUPAC Name:
[8-[2-(4-hydroxy-6-oxo-oxan-2-yl)ethyl]-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl] 2-methylbutanoate





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