Misoprostol

This page contains recent news articles, when available, and an overview of Misoprostol but does not offer medical advice. You should contact your physician with regard to any health issues or concerns.


Overview:

Misoprostol
(when available)

Pharmacology and use:
Misoprostol is a prostaglandin E1 (PGE1) analogue used for the treatment and prevention of stomach ulcers. When administered, misoprostol stimulates increased secretion of the protective mucus that lines the gastrointestinal tract and increases mucosal blood flow, thereby increasing mucosal integrity. It is sometimes co-prescribed with non-steroidal anti-inflammatory drugs (NSAIDs) to prevent the occurrence of gastric ulceration, a common adverse effect of the NSAIDs. Indicated for the treatment of ulceration (duodenal, gastric and NSAID induced) and prophylaxis for NSAID induced ulceration.

Mechanism Of Action:
Misoprostol seems to inhibit gastric acid secretion by a direct action on the parietal cells through binding to the prostaglandin receptor. The activity of this receptor is mediated by G proteins which normally activate adenylate cyclase. The indirect inhibition of adenylate cyclase by Misoprostol may be dependent on guanosine-5’-triphosphate (GTP). The significant cytoprotective actions of misoprostol are related to several mechanisms. These include: 1. Increased secretion of bicarbonate, 2. Considerable decrease in the volume and pepsin content of the gastric secretions, 3. It prevents harmful agents from disrupting the tight junctions between the epithelial cells which stops the subsequent back diffusion of H+ ions into the gastric mucosa, 4. Increased thickness of mucus layer, 5. Enhanced mucosal blood flow as a result of direct vasodilatation, 6. Stabilization of tissue lysozymes/vascular endothelium, and 7. Improvement of mucosal regeneration capacity.

News Articles on Misoprostol

New paper links "safe" abortion to maternal deaths  -  ‎Dec 21, 2009‎
What is more, a WHO study showed that "one out of every five women who had 'safe' misoprostol abortions failed to abort and required surgical intervention. ... eTaiwan News

Italy: RU-486 abortion pill will be available in hospitals  -  ‎Dec 10, 2009‎
A second pill, misoprostol, is used afterward to cause contractions and push the embryo out of the uterus. Italy already approved the so-called ... The Canadian Press

Govind Armstrong to Close Table 8 in Cooper Square Hotel  -  ‎Dec 21, 2009‎
Josh Woodward - who was... last month with killing his unborn fetus by lacing his girlfriend's panties with a drug called Misoprostol. ... Martiniboys.com

Recommendations for Prescribing NSAIDs in the Primary Care Setting  -  ‎Dec 28, 2009‎
Physicians should consider prescribing PPIs, double-dose histamine H 2 blockers, or misoprostol with NSAIDs for persons who must take NSAIDs, although they ... Medscape

Police Find Body of Unborn Baby Killed in Abortion in Christmas Gift Box  -  ‎Dec 15, 2009‎
...seven weeks into pregnancy to kill an unborn child, but the second part of the two-drug process, misoprostol, can be used to cause contractions. ... LifeNews.com

Men Gets Jail for Forcing Wife to Undergo Abortion  -  ‎Dec 28, 2009‎
She was forced to take Cytotec pills which contained misoprostol which is used in cases of gastric ulcers. The Dubai Criminal Court of First Instance on ... Khaleej Times

What they concealed, what we revealed and what happened afterwards  -  ‎Dec 17, 2009‎
Informanté discovered that abortion drugs - Cytotec or Misoprostol – are readily available on the streets of Windhoek while in the North, abortion doctors ... Informante

The Risk for Adverse Pregnancy Outcomes After Induced Pregnancy Termination  -  ‎Dec 17, 2009‎
Obviously, one has to choose the least traumatic approach and should use "cervical ripening" methods (laminaria, misoprostol) to induce the least amount of ... Medscape

Refusing to Provide Contraception to Women: Whose 'Right' Is it Anyway?  -  ‎Dec 11, 2009‎
What follows is my response to the above commenter: To your point about Cytotec: First off, while Cytotec (misoprostol) is used in medication abortion, ... RH Reality Check (blog)

Homerton Hospital apologises after midwives' errors lead to death of baby girl  -  ‎Dec 17, 2009‎
Mrs Willicombe, now 39, was prescribed two doses of Misoprostol, which meant her and her unborn child - the couple's first - needed extra attention. ... Hackney Gazette

Pain Meds Can Cause Serious Side Effects  -  ‎Dec 18, 2009‎
Another less common therapy that may be used is misoprostol (Cytotec). Celecoxib (Celebrex), a COX-2 specific NSAID, may also be considered an option for ... Greenwood Today

Anvisa entrega à PF remédio vendido ilegalmente pela internet  -  ‎Dec 14, 2009‎
O Cytotec é um dos nomes comerciais do misoprostol, uma substância abortiva. Nos hospitais, serve para induzir o parto em mulheres com dificuldades para ter ... G1.com.br

Clínicas abortivas tienden a desaparecer en Uruguay  -  ‎Dec 28, 2009‎
En entrevista con Ultimas Noticias, Cóppola explicó que la Sociedad de Ginecología va a impulsar el uso del misoprostol como medicamento esencial aprobado ... El Espectador Uruguay

Cóppola: tres años sin muertes por aborto  -  ‎Dec 29, 2009‎
...en los últimos 10 años, que casi la totalidad de los abortos se efectúan actualmente con Misoprostol y que las clínicas clandestinas desaparecieron. ... El Espectador Uruguay

Seis de cada mil mujeres, al año, hospitalizadas por abortos inseguros  -  ‎Dec 10, 2009‎
Tres de cada diez mujeres en México abortan con el uso del Misoprostol y el 14 por ciento usan los servicios de los proveedores tradicionales; ... La Jornada Aguascalientes

Farmaci proibiti tra Italia e Brasile  -  ‎Dec 19, 2009‎
Il Misoprostol o Cytotec è un gastroprotettore che in Italia viene impiegato per gli aborti terapeutici, in quanto favorisce la dilatazione del collo ... Musibrasil

Au Mexique, bataille acharnée sur le droit à l'avortement  -  ‎Jan 1, 2010‎
Velasco de Aleman, un établissement public géré par la ville de Mexico, elle attend que le misoprostol, une pilule abortive, déclenche les contractions. ... Le Monde

Anvisa e PF fecham farmácias e prendem 5 por venda de abortivo em Alagoas  -  ‎Dec 17, 2009‎
O Cytotec é um dos nomes comerciais do misoprostol, substância abortiva que só pode ser comercializada para hospitais e é utilizada para induzir partos ou ... G1.com.br

Piel de cordero  -  ‎Dec 28, 2009‎
...pudieran tomar misoprostol: un medicamento avalado por la Organización Mundial de la Salud que permite interrumpir una gestación en el curso de los tres ... Crítica Digital

Aborto y violencia contra la mujer  -  ‎Dec 14, 2009‎
Dos días más tarde volví al hospital, como me había dicho el médico y tomé la otra pastilla, el Misoprostol. Fue todo muy fácil�. ... Hazte Oir

"Sin proponérselo, Wikipedia se está convirtiendo en un medio de comunicacion ...  -  14 Nov 2009
Un buen ejemplo, ya superado, es cuando Wikipedia en español habló sobre el fármaco misoprostol. En 2007, informaban sobre el fármaco, pero no hablaban de ... Rebelión

Abortion Activists Reach Rural Tanzania  -  ‎Nov 12, 2009‎
In 2007, misoprostol was registered in Tanzania as a drug to stop postpartum hemorrhage (PPH). PPH is the leading cause of maternal mortality in Tanzania ... Huffington Post (blog)

Stupak is as Stupak Does  -  ‎Nov 13, 2009‎
I think that low-income women who have to induce their abortions with coathangers and black-market misoprostol are at risk either way. ... About - News & Issues (blog)

Treatment of retained placenta with misoprostol: a randomised controlled trial ...  -  ‎Oct 23, 2009‎
Medical treatment of retained placenta with prostaglandins E1 (misoprostol) could be cost-effective and easy-to-use and could be a life-saving option in ... 7thSpace Interactive (press release)

To treat acute ulcers in the stomach (gastric ulcers), or in the first part of ...  -  ‎Nov 11, 2009‎
Misoprostol protects the stomach lining from ulcerating effects of NSAIDs (such as aspirin and ibuprofen) and prevents stomach ulceration and related ulcer ... Pattaya Daily News

Patrick O'Brien: 'Most women in Uganda's villages deliver on their own'  -  ‎Oct 26, 2009‎
He helped staff in Kampala roll out the use of a pill called misoprostol that significantly reduces the risk of haemorrhage. Because it only costs a few ... BBC News

Cheap drug to make childbirth safer in poor countries  -  ‎Oct 22, 2009‎
The results of a clinical trial in rural India published last week in The Lancet medical journal indicate that misoprostol reduced the incidence of ... The Southern Times

'No conveyor belt'  -  ‎Nov 4, 2009‎
In fact, the benefits to health outweigh the risks to the extent that the World Health Organisation in 2005 placed both mifepristone and misoprostol on the ... Gisborne Herald

4th Pro-Life World Congress Calls Abortion "Mega-Genocide"  -  ‎Nov 10, 2009‎
...the "morning after" pill, systemic use contraceptive pills, injectable or subdermal implants, and the chemical abortifacient drug misoprostol. ... Lifesite

Water Is Key to Reducing Maternal Mortality  -  ‎Nov 4, 2009‎
..."There's a panoply of factors that contribute to maternal mortality--everything from (the drug) misoprostol not being available to treat postpartum ... Women's eNews

Mystery over how much drugs poisoning case mistress ingested  -  ‎Oct 26, 2009‎
Two of the drugs – misoprostol and methotrexate – can cause miscarriage or severe birth defects. A third, Diclofenac can cause devastating side-effects for ... WalesOnline

Abortion women told: 'see a lawyer first'  -  ‎Oct 25, 2009‎
...procuring her own miscarriage, while her partner Sergie Brennan, 21, was charged for procuring a miscarriage and supplying a drug, namely misoprostol. ... Brisbane Times

Consent for flu vaccine but not abortion?  -  ‎Oct 27, 2009‎
To prevent infection, she will be given antibiotics and possibly misoprostol, a medication to induce labor. The rest of the procedure involves pain ... Anchorage Daily News

Maternal mortality needs a multifaceted approach  -  ‎Oct 29, 2009‎
In an attempt to reduce maternal deaths from bleeding, the Ministry of Health has started pilot projects on the use of the drug misoprostol, an effective ... New Vision

CHILE: Teen Pregnancy, a Problem That Won't Go Away  -  ‎Nov 2, 2009‎
She drank herbal concoctions, took martial art classes and even considered buying misoprostol, known as the "abortion pill." But she had no money. ... IPS

Active Management of Third Stage of Labour May Increase Total Oxytocin ...  -  ‎Oct 22, 2009‎
...prostaglandin 15-methyl F2 alpha, or misoprostol), occurrence of hypotension requiring vasopressor administration, and estimated blood loss. ... DG News

Abortion, scientifically speaking  -  ‎Oct 26, 2009‎
One of the most common methods of medical abortion includes a combination of the drugs methotrexate (MTX) and misoprostol; the first stops the growth of ... McGill Daily

Family Planning initiative Hamilton  -  ‎Nov 1, 2009‎
Early Medical Abortion is the use of pills (Mifegyne, also knownas RU486, followed by misoprostol) to cause a miscarriage early in the pregnancy. ... Scoop.co.nz (press release)

State that outlawed kindness  -  ‎Oct 30, 2009‎
Veteran Brisbane obstetrician Adrienne Freeman, who is licensed to prescribe the abortion drug misoprostol, offered to defy the Queensland Medical Board and ... The Australian

Doctor guilty of poisoning pregnant lover  -  ‎Oct 20, 2009‎
Misoprostol is used to induce medical abortion, although this is not a licensed use of the drug in the UK. After contacting police with the liquids and ... UK Net Guide

Diputados aprueba una Ley que ya era Ley  -  ‎Nov 11, 2009‎
Sancionaron hoy una ley para que los medicamentos con misoprostol, una droga abortiva, se vendan bajo receta. Sin embargo, por disposición de la ANMAT, ... Los Andes (Argentina)

Voice For Life opposed to `abortion conveyer-belt'  -  ‎Oct 22, 2009‎
After 1-3 days, Misoprostol is administered to expel the `corpse'. This drug can be administered in the clinic or at home. Bleeding and the expulsion of the ... Scoop.co.nz (press release)

Accorsi Alerta por Falta de Medicamento  -  ‎Oct 30, 2009‎
...(ORBE) El diputado PPD, Enrique Accorsi, alertó sobre la falta del medicamento Misoprostol en los servicios de obstetricia y ginecología. ... Chile.com

Tucumán: PREOCUPACIÓN Y RECHAZO POR EL “TELÉFONO DE LA MUERTEâ€?. Por Mónica del Río  -  ‎Oct 27, 2009‎
...“Mujeres sobre las olas� (Women on waves) con la finalidad de asesorar sobre el modo de abortar con misoprostol hasta la semana 12 del embarazo. ... Periodismo de Verdad

Denuncian que una mujer abortó y la enviaron a casa para que ella misma se tratara  -  ‎Oct 26, 2009‎
..."El tratamiento era con Misoprostol y consistía en meterme tres pastillas por la vagina y en cuestión de horas empezaría a expulsarlo", señala en la misiva ... Cadena Ser

Feroz resistencia al aborto legal en América Latina  -  ‎Oct 22, 2009‎
...sino la aparición de un medicamento que se llama Misoprostol, que se receta para el tratamiento de úlceras gástricas, pero que tiene un efecto abortivo. ... El País (España)

La Ru486 allunga l'aborto  -  ‎Oct 22, 2009‎
...tra la prima somministrazione di mifepristone (che uccide il feto) e la seconda fase con il misoprostol, la prostaglandina che provoca l'espulsione. ... Libero-News.it

从英国一桩奇案é‡?新审视婚外æ?‹  -  ‎Nov 1, 2009‎
...警方化验结果,饮料里å?«æœ‰Dicofenac, Misoprostol and Methotrexate,都是å?¯èƒ½å¯¼è‡´å­•妇æµ?产的è?¯ç‰©ã€‚埃伦被æ?•,最终被é€?上英国最高法庭,Old Bailey。 ... 新浪网 (博客)

騰é¾?說事:å?¦çœ¼ç›¸çœ‹å©šå¤–戀  -  ‎Oct 27, 2009‎
...警方化驗çµ?果,飲料è£?å?«æœ‰Dicofenac, Misoprostol and Methotrexate,都是å?¯èƒ½å°Žè‡´å­•婦æµ?產的藥物。埃倫被æ?•,最終被é€?上英國最高法庭,Old Bailey。 ... BBC中文網

Trigeminus: Schmerzfrei mit Gen-GABA  -  ‎Oct 29, 2009‎
Eine Besonderheit bei MS-Kranken mit Trigeminusneuralgie ist das Prostaglandin-E-Analogon Misoprostol, das primär zur Behandlung bei medikamentenbedingten ... DocCheck News

Las jornadas científicas de la Sociedad Valenciana de Contracepción y Salud ...  -  ‎Oct 28, 2009‎
El reconocimiento fue para el trabajo titulado: Shock tóxico por clostriduim Sordellii asociado a aborto con mifepristona más misoprostol. ... Noticias Médicas (Comunicado de prensa)

(Vulcano - giornale universitario della Statale di Milano) Ops…Good Morning ...  -  ‎Oct 28, 2009‎
...la quale può essere assunta fino a 8 settimane dopo il rapporto e che prevede l'assunzione di due farmaci (mifepristone e misoprostol) di cui il primo è ... Radicali Milano

Las autoridades buscan reducir los abortos con su propia 'píldora del día después'  -  ‎Nov 2, 2009‎
Pero el aborto, advierte, lleva riesgos por lo que se impulsa un plan para sustituir la vía quirúrgica por la medicamentosa —un 40% se hacen con Misoprostol ... CUBAENCUENTRO.com

Venta de medicamentos por Internet y ferias libres es un peligro latente  -  ‎Oct 20, 2009‎
Tal es el caso de misoprostol (Misotrol®) un efectivo antiulceroso gástrico, que entre sus efectos adversos es provocar abortos, por lo que está ... universia.cl

Misunderstood misoprostol  -  Jun 5, 2006
Cheap drug could prevent millions of deaths from postpartum hemorrhage, but governments are skittish to embrace it because it also can induce abortions. ... Salon

Abortion Might Outgrow Its Need for Roe v. Wade  -  Oct 2, 2005
In the United States, misoprostol is typically used off label with the ... A spokeswoman for Pfizer, which sells misoprostol under the name Cytotec, ... New York Times

Scientists Will Gather to Discuss Safety of Abortion Pill  -  May 11, 2006
The oral administration of misoprostol is more common in Europe, but vaginal use there has been growing. Ann Furedi, chief executive of the British ... New York Times

Abortion Pill Treatments Tied to Two New Deaths  -  Mar 17, 2006
Doctors say misoprostol has been given in the vagina because it reduces the nausea ... For them, the dose of misoprostol was twice as high, taken through ... Bloomberg

Article could kindle abortion pill fight.  -  Dec 1, 2005
It is used with a second drug, misoprostol, to induce early-stage abortions. ... Nor does vaginal administration of misoprostol increase the risk of ... Free with registration - Boston Globe - AccessMyLibrary.com

Medical Abortion Won't Affect Future Pregnancies  -  Aug 15, 2007
There are three different methods of medical abortion: a drug called misoprostol used alone; methotrexate followed by misoprostol; and mifepristone followed ... Washington Post

Study Compares Oral, Vaginal Use of Abortion Drug  -  Jun 7, 2007
While the use of another drug, mifepristone, followed by misoprostol, is the only approved method ... Among women who took misoprostol at 12-hour intervals, ... Washington Post

RU-486 did not cause woman's death  -  Apr 11, 2006
Additionally, all of the Californians who died after taking the drug were given misoprostol vaginally, rather than orally, which doctors are no longer ... Salon

FDA Issues Infection Warning on Abortion Pill  -  Jul 19, 2005
When followed by another medicine, misoprostol, the pregnancy is terminated. The FDA's instructions call for women to swallow both pills, but most abortion ... FOXNews

Deaths After Abortion Pill to Be Studied by Officials  -  Nov 23, 2005
But in the United States, most physicians give Mifeprex and an accompanying drug, misoprostol, in a regimen that involves inserting misoprostol vaginally. ... New York Times

Nurse gave wrong woman abortion  -  Jul 18, 2008
Ms Downer failed to carry out an identity check and gave a drug, Misoprostol, to a woman who was due to have an initial consultation. ... BBC News

Mifepristone and misoprostol for abortion  -  Sep 29, 2008
First, your doctor gives you a dose of mifepristone tablets by mouth. Mifepristone causes the placenta to separate from the endometrium. ... MSN Health & Fitness

FDA: Unclear If Abortion Pill Causes Infection  -  May 17, 2006
When followed two days later by another medicine, misoprostol, to induce contractions, a pregnancy is terminated. Opponents of RU-486 have pointed to the ... FOXNews

Abortion Pill Investigated in Four California Deaths; The FDA warns …  -  Aug 15, 2005
Misoprostol, which is not a Danco product, has been in use since the mid-1980s. ... Studies have shown that taking the misoprostol vaginally makes the drug ... Pay-Per-View - Los Angeles Times - ProQuest Archiver

Hundreds in baby drug scandal  -  Nov 20, 2007
In August 2000, the maker of misoprostol, Searle, since acquired by ... Misoprostol is more likely to result in an excessive uterine response if given in ... Sydney Morning Herald

Abortion drug off-label use could be fatal  -  Jun 17, 2008
University of Michigan scientists says that the drug misoprostol is US Food ... The off-label use of misoprostol drug may be responsible for a handful of ... United Press International

Beat-up alleged on drug dangers  -  Nov 21, 2007
It asked "anybody who gave birth to a child at the St George Hospital between 1997 and 2006 who was administered the drug misoprostol for the induction of ... The Australian

Abortion Pill Effective, Safe Treatment for Miscarriage  -  Aug 24, 2005
The treatment is called misoprostol, a pill used to prevent the risk of developing a ... Physicians have begun prescribing misoprostol to women who have ... FOXNews

RU486 delays prompt use of other abortion drugs  -  Sep 18, 2006
Misoprostol, she said, was also being used for late-term abortions — that is, ... Both methotrexate and misoprostol are licensed in Australia, ... The Age

Abortion pill safe to take at home  -  Oct 12, 2007
..."Regarding abortion at home, there is an increasing body of evidence from both developed and developing countries that home use of mifepristone/misoprostol ... TVNZ

Uganda: Govt Approves Low-Cost Drug to Control Maternal Bleeding  -  Sep 18, 2008
Misoprostol can be administered to women immediately after childbirth. ... Mallinga said although Misoprostol was available in the country, ... AllAfrica.com

Africa: Cheap Drug to Make Childbirth Safer in Poor Countries  -  Oct 6, 2006
The abortion drug misoprostol can be used to help save the lives of women ... "The researchers showed that giving women misoprostol after birth is a safe, ... AllAfrica.com

SUSPECT'S GIRLFRIEND 'ANGRY, UPSET'  -  Mar 3, 2007
..."Do not take misoprostol to prevent ulcers if you are pregnant or plan to become ... Misoprostol may cause miscarriages, premature labor or birth defects. ... Pay-Per-View - Daily Press - ProQuest Archiver

Women 'can have safe abortions at home'  -  Feb 16, 2006
In a medical abortion, a woman takes a tablet of the drug mifepristone under supervision before returning two days later to take four pills of misoprostol ... Telegraph.co.uk

Judge gives go-ahead to terminate pregnancy of girl, 12  -  Sep 26, 2008
Justice Wilson made a declaration which allowed government doctors to terminate the child's pregnancy by administering the drug misoprostol. NEWS.com.au

DEATHS OF WOMEN WHO USED RU-486 PROBED FOUR CALIFORNIA …  -  Aug 21, 2005
Misoprostol, which is not a Danco product, has been in use since the mid-1980s. ... Studies have shown that taking the misoprostol vaginally makes the drug ... $2.95 - St. Paul Pioneer Press - NewsBank

Experts: Labor drug's safe, in right hands  -  Jan 25, 2007
...[Abreu] faces a charge that she took three Misoprostol pills over two days ... Women's health advocates say that Misoprostol, the drug that a Lawrence teen ... Pay-Per-View - Boston Herald - ProQuest Archiver

Uganda: Misoprostol Will Reduce Maternal Mortality Rate  -  Jul 18, 2006
Kampala — THE 505 per 100, 000 live births is a shameful maternal mortality rate for modern Uganda. The figure has not declined substantially over the past ... AllAfrica.com

The other abortion pill  -  Mar 26, 2008
That drug is a "little white pill" called misoprostol (brand name: Cytotec). In the US, misoprostol is used in combination with mifepristone (RU-486) for ... Salon

DA declines to seek murder charges in abortion case  -  Mar 29, 2007
Cytotec is the brand name for misoprostol, which forms part of a government-approved abortion method. It is typically prescribed for ulcers. ... Boston Globe

Rare bacteria connect women's deaths.  -  Nov 24, 2005
FDA guidelines say RU-486 should be given in the first seven weeks of pregnancy and call for its follow-up drug, misoprostol, to be given orally during a ... Free with registration - Contra Costa Times - AccessMyLibrary.com

Uganda: Cheap, Easy Drug to Save Mothers From Bleeding to Death  -  Jan 23, 2008
Kampala — If misoprostol, a drug that treats and prevents excessive ... Misoprostol is a single dose white generic tablet, which a woman can put under her ... AllAfrica.com

Abortion doctor says pill is safe  -  Oct 21, 2006
RU486, also known as mifepristone, is used in conjunction with misoprostol, which expels the foetus. Professor De Costa said all the women had an abortion ... The Age

Oral vs. vaginal misoprostol for cervical ripening.(Tips)  -  Dec 1, 2005
Labor induction during pregnancy is sometimes necessary when the benefits of intervening are greater than the risks of continuing the pregnancy. ... Free with registration - American Family Physician - AccessMyLibrary.com

Hospital gets abortion drug  -  Aug 29, 2007
Dr McGee is already using a drug called misoprostol on its own to carry out these terminations, but she said using RU486 before misoprostol was a more ... Sydney Morning Herald

Vaginal misoprostol for cervical ripening in term pregnancy.(FPIN's …  -  Feb 1, 2006
How safe and effective is vaginal misoprostol (Cytotec) for cervical ripening in a ... Low-dose (25 mcg) intravaginal misoprostol appears to be safe and ... Free with registration - American Family Physician - AccessMyLibrary.com

Misoprostol (Systemic).  -  Oct 27, 2005
Misoprostol (mye-soe-PROST-ole ) is taken to prevent stomach ulcers in patients taking anti-inflammatory drugs, including aspirin. Misoprostol may also be ... Free with registration - USP DI-Volume II, Advice for the... - AccessMyLibrary.com

Lincoln Pharmaceuticals applied for new patent for MISOPROSTOL  -  Aug 28, 2006
Lincoln Pharmaceuticals Ltd has announced that the Company has applied for the patent for Pharmaceutical composition containing a hormone MISOPROSTOL for ... Equity Bulls

Kenya: Abortion Pill Available Over the Counter  -  Apr 7, 2007
One is advised that a combination of misoprostol and mifeprex drugs is ... The site says mifepristone and misoprostol are for early abortion - about eight ... AllAfrica.com

Drug Offers Alternative to Surgical Treatment After Miscarriage  -  Aug 26, 2005
The drug, misoprostol, has been used to reduce the risk of stomach ulcers that ... Misoprostol is now more commonly used to induce labor, as it stimulates ... emaxhealth.com

Life blood: drug stops mothers' bleeding after births.(postpartum …  -  Oct 14, 2006
The drug in the new study is misoprostol. Because it causes uterine ... Some doctors have suggested giving misoprostol, which is manufactured as a tablet, ... $4.95 - Science News - ECNext

Rare but fatal outcome: four deaths may trace to abortion pill.(This...  -  Dec 3, 2005
Misoprostol causes uterine contractions that expel the fetal tissue. Cramping and bleeding are typical side effects of the treatment. ... Free with registration - Science News - AccessMyLibrary.com

In low-resource settings, misoprostol can reduce risk of postpartum …  -  Mar 1, 2007
In a randomized, controlled trial in rural India, women who took oral misoprostol after delivery were significantly less likely than those who took a ... $4.95 - International Family Planning Perspectiv... - ECNext

Diclofenac and Misoprostol (Systemic).  -  Feb 1, 2006
Diclofenac and misoprostol (dye-KLOE-fen-ak and mye-soe-PROST-ole )combination is used for patients with arthritis who may develop stomach ulcers from ... Free with registration - USP DI-Volume II, Advice for the... - AccessMyLibrary.com

Article: Oral misoprostol as effective as oxytocin injection for...  -  Sep 1, 2005
Oral misoprostol as effective as oxytocin injection for treating postpartum bleeding.(Clinical report) ... find OB GYN News articles. Pay-Per-View - OB GYN News - HighBeam Research

Parliament to debate plans to let nurses carry out abortions  -  Jul 7, 2008
Currently, the Abortion Act 1967 prevents nurses from prescribing the drugs mifepristone and misoprostol, which are needed for an EMA. ... Healthcare Republic - Healthcare Republic

… pregnancy safer in Myanmar: introducing misoprostol to prevent...  -  Nov 1, 2007
IN Myanmar, we carried out a successful pilot intervention with the prostaglandin misoprostol in the active management of the third stage of labour, ... $4.95 - Reproductive Health Matters - ECNext

Oral misoprostol as effective as oxytocin injection for treating...  -  Sep 1, 2005
QUEBEC CITY -- Oral misoprostol appears to be as effective as oxytocin by injection in reducing blood loss at delivery, but is associated with an increased ... Free with registration - OB GYN News - AccessMyLibrary.com

Diclofenac and Misoprostol Side Effects from Consumer Reports Health.  -  Jan 1, 2006
For female patients: Do not take diclofenac and misoprostol if you are pregnant or plan to become ... Full Alert. Do not take diclofenac and misoprostol if ... consumerreports.org

Mifepristone-Misoprostol Medical Abortion Mortality  -  Apr 27, 2006
Medical abortion is a non-surgical option for women who elect to terminate a pregnancy. In September 2000, the United States Food and Drug Administration ... Medscape

Misoprostol alone for medical abortion in the US.(ROUND UP: Research)(...  -  May 1, 2005
Misoprostol alone for medical abortion in the US.(ROUND UP: Research)(Brief Article) ... find Reproductive Health Matters articles. Pay-Per-View - Reproductive Health Matters - HighBeam Research

Woman charged with attempting to abort child with drug; Infant girl …  -  Jan 24, 2007
It is illegal in the United States to use misoprostol on its own to cause an abortion. ... Misoprostol was found in the baby's urine, according to reports. ... Eagle Tribune

Vaginal misoprostol for cervical ripening in term pregnancy.(FPIN's …  -  Feb 1, 2006
Clinical Question Evidence-Based Answer Low-dose (25 mcg) intravaginal misoprostol appears to be safe and effective for cervical ripening in term pregnancy ... $4.95 - American Family Physician - ECNext

Nigeria approves misoprostol for use in hospitals and clinics  -  Apr 3, 2006
When a shipment of round, white tablets of the generic drug misoprostol lands in Nigeria this week, that country will become the first ever to allow ... News-Medical.net

Drug Prevents Postpartum Hemorrhage In Resource Poor Settings  -  Oct 9, 2006
The drug misoprostol provides a safe, convenient, and inexpensive means to ... "The researchers showed that giving women misoprostol after birth is a safe ... Medical News Today - Medical News Today (press release)

Article: Vaginal misoprostol for early failed pregnancy.(Obstetrics) ...  -  May 15, 2005
Vaginal misoprostol for early failed pregnancy.(Obstetrics) ... find OB GYN News articles. NEW YORK -- Vaginal misoprostol is an effective alternative to ... Pay-Per-View - OB GYN News - HighBeam Research

Popular Pill For Inducing Labor Found Effective, But Concerns Remain  -  Apr 21, 2006
The pill - a prostaglandin known generically as misoprostol and sold as ... "Due to the limited evidence about the safety, oral misoprostol should be used ... Medical News Today - Medical News Today (press release)

Africa: Wait for Clinical Trial Data Causes 'Avoidable Deaths'  -  Oct 2, 2006
These include oral rehydration to treat diarrhoea, male circumcision to prevent HIV infection and the drug misoprostol to prevent haemorrhage in women who ... AllAfrica.com

Abortion pill shifts focus off Roe's fate ; Even if the John Roberts...  -  Oct 9, 2005
When the government in response restricted access to misoprostol, drug smugglers ... In the United States, misoprostol is typically used off-label with the ... Pay-Per-View - Orlando Sentinel - ProQuest Archiver

US tries to stop WHO from backing two abortion pills  -  Apr 22, 2005
For the first time they approved two pills, to be used in combination for the termination of early pregnancy, called Mifepristone and Misoprostol. ... Taipei Times - Taipei Times

Prostaglandin analog to prevent NSAID-induced peptic ulcer  -  Jan 7, 2008
Misoprostol is taken two times a day, or four times a day in divided doses. ... Misoprostol reduces the amount of acid produced by the stomach and enhances ... WebMD

Learn about Diclofenac and Misoprostol from Consumer Reports Health.  -  Jan 1, 2006
For female patients: Do not take diclofenac and misoprostol if you are pregnant or plan to become ... Full Alert. The combination of diclofenac and ... consumerreports.org

UC Berkeley team helps win approval for life-saving drug for African ...  -  Mar 28, 2006
Misoprostol has been marketed since 1987 for treatment of gastric ulcers. ... After its patent expired in 2000, interest in misoprostol as a PPH medication ... eurekalert.org

2 more RU 486 deaths trigger renewed calls for suspension of …  -  Mar 20, 2006
A second drug, misoprostol, is taken two days after mifepristone and causes the uterus to contract, expelling the baby. The FDA's approved regimen calls for ... BP News

Abortion Pill Death Rate 'Very Low'  -  Jul 21, 2005
Misoprostol is taken two days after Mifeprex to complete an abortion. The two drugs were approved by the FDA as one regimen in September 2000. ... Daily News Central

Article: Early pregnancy failure: misoprostol may be good alternative...  -  Sep 1, 2006
Pregnancies that fail in the first trimester-ones that end in embryonic or fetal death or in incomplete spontaneous abortion, ones whose inevitable outcome ... Pay-Per-View - Perspectives on Sexual and Reproductive... - HighBeam Research

PHARMACY TODAY - The many faces of Cytotec  -  Oct 18, 2006
For such conditions, misoprostol is prescribed as one tablet four times to be ... However, misoprostol has a side effect that has proved controversial. ... Jamaica Gleaner

Article: In low-resource settings, misoprostol can reduce risk of …  -  Mar 1, 2007
In low-resource settings, misoprostol can reduce risk of postpartum hemorrhage. ... find International Family Planning Perspectives articles. Pay-Per-View - International Family Planning Perspectiv... - HighBeam Research

Abortion drug's off-label use may have led to deaths  -  Jun 16, 2008
M studies indicate that oral use of RU-486's companion drug misoprostol is safe, ... The drug misoprostol is FDA-approved to be taken by mouth along with ... Eureka! Science News

Misoprostol could play an important part in reducing complications of...  -  Oct 3, 2005
A relatively cheap and easy to use drug could save the lives of thousands of women in the developing world, according to a study in this week's British ... News-Medical.net

Effect of sublingual misoprostol on severe postpartum haemorrhage  -  Oct 6, 2005
By BMJ, A relatively cheap and easy to use drug could save the lives of thousands of women in the developing world, according to a study in recent BMJ. ... RxPG NEWS

… of mifepristone and vaginal misoprostol for medical abortion may...  -  May 1, 2006
The aim of medical abortion is to provide complete and safe expulsion of the fetus in the shortest time possible. The recommended regimen is 200 mg ... Free with registration - Reproductive Health Matters - AccessMyLibrary.com

Studies on Misoprostol Use To Prevent Postpartum Hemorrhage, Folic …  -  Oct 5, 2005
..."Effect of sublingual misoprostol on severe postpartum hemorrhage in a primary health center in Guinea-Bissau: randomized double blind clinical trial," BMJ ... Medical News Today - Medical News Today (press release)

… Health; Simultaneous vaginal misoprostol/oral mifepristone therapy...  -  Jun 26, 2006
Two patients required repeat misoprostol. Median time from medication to abortion was 7 h. Most women (92%) strongly preferred taking all medications in the ... Pay-Per-View - OBGYN & Reproduction Week - Factiva, from Dow Jones

Vaginal misoprostol for early failed pregnancy.(Obstetrics)  -  May 15, 2005
NEW YORK -- Vaginal misoprostol is an effective alternative to surgical intervention for management of early pregnancy failure, with a high degree of ... Pay-Per-View - OB GYN News - Factiva, from Dow Jones

Misoprostol reduces postpartum hemorrhage.(Brief Article)  -  Dec 1, 2005
Postpartum administration of misoprostol, which does not require refrigeration, beneath the tongue could reduce morbidity and mortality from hemorrhage ... $4.95 - International Family Planning Perspectiv... - ECNext

Abortion Pill Slated for New FDA Review  -  Feb 23, 2006
Most abortion providers give 200 milligrams of Mifeprex to women orally, then instruct them to take 800 milligrams of misoprostol vaginally at home. ... Women's eNews

… between mifepristone and misoprostol: preliminary findings.(ROUND...  -  Nov 1, 2005
Shortening the interval between mifepristone and misoprostol: preliminary findings.(ROUND UP: Medical Abortion)(Brief Article) ... find Reproductive Health ... Pay-Per-View - Reproductive Health Matters - HighBeam Research

FPIN's Clinical Inquiries  -  Feb 1, 2006
How safe and effective is vaginal misoprostol (Cytotec) for cervical ripening in a ... Low-dose (25 mcg) intravaginal misoprostol appears to be safe and ... AAFP News Now

Misoprostol alone for medical abortion in the US.(ROUND UP: Research)(...  -  May 1, 2005
The most common drug regime for medical abortion is mifepristone in combination with misoprostol. Where mifepfistone is hot available, misoprostol alone is ... $4.95 - Reproductive Health Matters - ECNext

FDA Officials At House Hearing Say They Do Not Know If Mifeprex Use …  -  May 21, 2006
The agency in March reported that two other women who took the Mifeprex-misoprostol regimen had died and issued a public health advisory urging physicians ... Medical News Today - Medical News Today (press release)

… pregnancy safer in Myanmar: introducing misoprostol to prevent...  -  Nov 1, 2007
Making pregnancy safer in Myanmar: introducing misoprostol to prevent post-partum haemorrhage as part of active management of the third stage of labour. Pay-Per-View - Reproductive Health Matters - HighBeam Research

Forum: Stop the bloodshed and pass Holly's Law  -  Feb 4, 2006
A second drug, misoprostol ("Cytotec"), is needed to induce contractions to expel the dead embryo, but Cytotec's manufacturer repeatedly warned against its ... washingtontimes.com

Article: Home-use of misoprostol highly acceptable for Swedish women ...  -  Nov 1, 2005
Home-use of misoprostol highly acceptable for Swedish women and their partners.(ROUND UP: Medical Abortion)(Brief Article) ... find Reproductive Health ... Pay-Per-View - Reproductive Health Matters - HighBeam Research

Obstetrics; Ulcer drug, misoprostol, can prevent excessive postpartum...  -  Oct 30, 2006
2006 OCT 30 - (NewsRx.com) -- The drug misoprostol, normally used to treat ulcers, was found to prevent excessive postpartum bleeding, a common cause of ... Pay-Per-View - OBGYN & Reproduction Week - Factiva, from Dow Jones

Article: Medical abortion: a fact sheet: the following information...  -  Nov 1, 2005
Article: Home use of two doses of misoprostol after mifepristone ... ... Article: Evaluation of the efficacy of mifepristone/misoprostol and ... ... Pay-Per-View - Reproductive Health Matters - HighBeam Research

Some Doctors Voice Worry Over Abortion Pills' Safety  -  Apr 1, 2006
When followed up by another drug, misoprostol, Mifeprex induces a ... This method allowed women to take lower doses of misoprostol and meant fewer office ... New York Times

Starrick: Aborting the Facts  -  Apr 24, 2006
While it is true that all four took both Mifeprex and Misoprostol, sepsis is a known to be a risk for any type of abortion. ... R-N University Observer

Pregnancy is not a disease  -  Jul 24, 2006
Misoprostol carries its own risks. It can weaken the body's ability to fight disease. There are concerns about the lasting effect on cervical and uterine ... onlineopinion.com.au

Article: High-dose misoprostol deemed safe, effective.(Obstetrics) -...  -  Feb 15, 2005
High-dose misoprostol deemed safe, effective.(Obstetrics) ... find OB GYN News articles. WHITE SULPHUR SPRINGS, W.VA. -- A high dose of vaginal misoprostol ... Pay-Per-View - OB GYN News - HighBeam Research

Article: Misoprostol reduces postpartum hemorrhage.(Brief Article) - ...  -  Dec 1, 2005
Misoprostol reduces postpartum hemorrhage.(Brief Article) ... find International Family Planning Perspectives articles. Postpartum administration of ... Pay-Per-View - International Family Planning Perspectiv... - HighBeam Research

Popular Pill for Inducing Labor Found Effective, But Concerns Remain  -  Apr 17, 2006
The pill " a prostaglandin known generically as misoprostol and sold as ... "Due to the limited evidence about the safety, oral misoprostol should be used ... newswise.com

Common but quiet: Border brings easy access to abortion 'wonder drug'  -  Feb 10, 2008
If used properly, misoprostol is about 85 percent effective in inducing abortion, ... Misoprostol has been a popular option for women in countries where ... Brownsville Herald

Drug prevents postpartum hemorrhage in resource poor settings  -  Sep 10, 2006
The drug misoprostol provides a safe, convenient, and inexpensive means to ... "The researchers showed that giving women misoprostol after birth is a safe ... innovations report

Article: Portuguese women learn about misoprostol from Women on …  -  May 1, 2005
Portuguese women learn about misoprostol from Women on Waves.(ROUND UP: Service Delivery)(Brief Article) ... find Reproductive Health Matters articles. Pay-Per-View - Reproductive Health Matters - HighBeam Research

Article: WHO adds mifepristone and misoprostol to essential medicines...  -  Nov 1, 2005
WHO adds mifepristone and misoprostol to essential medicines list.(ROUND UP: Medical Abortion)(Brief Article) ... find Reproductive Health Matters articles. Pay-Per-View - Reproductive Health Matters - HighBeam Research

Cytotec Safe and Effective for Management of Early Pregnancy Failure  -  Aug 24, 2005
The active ingredient in Cytotec, misoprostol, is combined with mifepristone in the abortion pill that is marketed as Mifeprex. ... MedPage Today

Officials Investigate Abortion Pill Deaths  -  Aug 1, 2005
A second drug, misoprostol, taken 24 hours later, induces uterine contractions. Many abortion providers instruct women to administer misoprostol at home ... Women's eNews

RU486 Abortion pill hearings begin in Australia  -  Feb 3, 2006
Dr Sharman Stone, said yesterday the issue was not about Misoprostol, but rather that "the TGA should make the decision about any drugs - that is its job. ... Wikinews

Managing incomplete miscarriages: what's better,  -  May 30, 2005
The researchers determined that misoprostol is successful in only 53% of ... Despite the lower efficacy of misoprostol, according to the article "some women ... National Review of Medicine

Brand Names/Synonyms:
Misoprostol is also known by the following brand names and/or synonymsArthrotec; Cytotec; MISOPROSTOL 1 : 100 HPMC DISPERSION; Misoprostol; Misoprostol 1:100; Misoprostol [Usan:Ban:Inn:Jan]; Misoprostolum [Inn-Latin]

Drug Category:
Misoprostol is categorized under the following by the FDA: Oxytocics; Anti-ulcer Agents; Abortifacient Agents; Prostaglandins; ATC:A02BB01

Dosage Forms:
TABLET

Absorption:
Misoprostol is extensively absorbed.

Interactions:
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Chemical IUPAC Name:
methyl7-[3-hydroxy-2-(4-hydroxy-4-methyl-oct-1-enyl)-5-oxo-cyclopentyl]heptanoate





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