|
 |
MitomycinThis page contains recent news articles, when available, and an overview of Mitomycin but does not offer medical advice. You should contact your physician with regard to any health issues or concerns.Overview: Mitomycin (when available) Mitomycin is an antibiotic which has been shown to have antitumor activity. Mitomycin selectively inhibits the synthesis of deoxyribonucleic acid (DNA). The guanine and cytosine content of the targeted DNA correlates with the degree of mitomycin-induced cross-linking. At high concentrations of the drug, cellular vitro to inhibit B cell, T cell, and macrophage proliferation and impair antigen presentation, as well as the secretion of interferon gamma, TNFa, and Bleomycin (which has major effects in G2 and M phases). Mitomycin is indicated in the palliative treatment of squamous cell carcinoma, lymphomas, testicular carcinoma, alone or in combination with other drugs. For treatment of malignant neoplasm of lip, oral cavity, pharynx, digestive organs, peritoneum, female breast, urinary bladder Mechanism Of Action: Mitomycin is a purple antibiotic isolated from Streptomyces caespitosus. Mitomycin is activated in vivo to a bifunctional and trifunctional alkylating agent. Binding to DNA leads to cross-linking and inhibition of DNA synthesis and function. Mitomycin is cell cycle phase-nonspecific. There is some evidence of lesser inhibition of RNA and protein synthesis. News Articles on Mitomycin Successful treatment of tracheal stenosis by rigid bronchoscopy and topical ... - Jan 4, 2010 Topical application of Mitomycin C, a potent fibroblast inhibitor reduces granulation tissue formation and prevents recurrence. 7thSpace Interactive (press release) Bilateral choanal atresia in an adult - management with mitomycin C and ... - Dec 11, 2009 The orifice was widened with a curette and, to prevent stenosis, mitomycin-C (1 mg/ml) was applied topically to the nasopharyngeal orifice for 5 minutes. ... 7thSpace Interactive (press release) Monoketone analogs of curcumin, a new class of Fanconi anemia pathway inhibitors - Dec 31, 2009 Survival assays revealed that EF24 specifically sensitizes FA-competent cells to the DNA crosslinking agent mitomycin C (MMC). In addition, in contrast with ... 7thSpace Interactive (press release) PALB2 variants in hereditary and unselected Finnish Prostate cancer cases - Dec 15, 2009 Hypersensitivity to mitomycin C (MMC) of lymphoblasts from individuals from the family with 1592delT revealed haploinsufficiency among carriers with altered ... 7thSpace Interactive (press release) Mắt má»™ng thịt, nên Ä‘i khám sá»›m - Dec 16, 2009 Vá»›i các phÆ°Æ¡ng pháp mổ cÅ© nhÆ° cắt má»™ng, để hở củng mạc, di chuyển hÆ°á»›ng Ä‘i của đầu má»™ng, ghép má»™ng kết hợp vá»›i áp tia beta và nhá»? Mitomycin sau phẫu ... Thanh Niên Higher success rate found for initial trabeculectomy cases with MMC compared ... - Nov 10, 2009 Open-angle glaucoma cases that underwent initial trabeculectomy with mitomycin C showed better overall results than those that had repeat trabeculectomy ... OSN SuperSite Mitomycin C induces bystander killing in homogeneous and heterogeneous ... - Oct 21, 2009 Hence, chemotherapy induced bystander phenomenon in hepatoma cells was explored by utilizing Mitomycin C (MMC). Results: MMC induced bystander killing was ... 7thSpace Interactive (press release) Advanced Surface Ablation Following LASIK Successful: Presented at AAO-PAAO - Oct 27, 2009 He added that there has only been a single report of PRK plus mitomycin C as a safe and effective option. Researchers performed a retrospective review of 43 ... DG News Gemcitabine more effective than mytomicin for recurrent bladder transitional ... - Oct 27, 2009 Gemcitabine was more effective and had a lower toxicity than mitomycin for treatment of patients with recurrent superficial bladder cancer. ... HemOncToday Tube shunt surgery has higher success rate than trabeculectomy with MMC at 3 years - Nov 11, 2009 ...results of the Tube Versus Trabeculectomy Study have found that tube shunts have a higher percentage of success than trabeculectomy with mitomycin C, ... OSN SuperSite Gemzar® More Effective than Mutamycin® for Recurrent Superficial Bladder Cancer - Oct 23, 2009 Researchers from Italy have reported that intrabladder treatment with Gemzar® (gemcitabine) is more effective than Mutamycin® (mitomycin C) for the ... Cancer Consultants BSD Medical Reports Hyperthermia Therapy Contributes to Improved Survival Rate ... - Oct 30, 2009 57.5% tumor recurrence rate for those treated with Mitomycin-C alone, p = 0.002). J. van der Zee, et al., reported in The Lancet in 2000 on a study of 101 ... WELT ONLINE Topical drugs may overtake NSAIDs for control of postsurgical haze and ... - Oct 25, 2009 SAN FRANCISCO — While topical NSAIDs will continue to play a role in pain management after corneal refractive surgery, topical mitomycin C and cyclosporine ... OSN SuperSite Leading Vision Correction Experts in Trusted LASIK Surgeons Directory Educate ... - Nov 5, 2009 ...were co-authors on a presentation demonstrating that wavefront-guided and conventional PRK followed by the applicaton of Mitomycin C are both effective ... PR Web (press release) Mitomycin C, Mutamycin - May 25, 2007 Mitomycin is an intravenous (IV) medication. It is usually given once every 4 to 8 weeks. The type and extent of a cancer determines the exact dose and ... WebMD … combination of intravesical and BCG electromotive mitomycin for... - Nov 1, 2006 Di Stasi SM et al. (2006) Sequential BCG and electromotive mitomycin versus BCG alone for high-risk superficial bladder cancer: a randomised controlled ... Nature.com New Anal Cancer Therapy Fails to Improve Outcomes - Apr 22, 2008 The five-year overall survival rate was 75 percent in the mitomycin group and 70 percent in the ... Severe blood toxicity was worse in the mitomycin group. ... Washington Post … sclerectomy (PDS) with intraoperative mitomycin C (MMC) augmentatio... - Apr 20, 2007 To report the safety and efficacy of intraoperative mitomycin (MMC) augmentation of ... Mitomycin C (MMC) augmentation increases the IOP lowering effect of ... Nature.com Deep sclerectomy with mitomycin C in failed trabeculectomy - Nov 25, 2005 Correspondence: G Rebolleda, Glaucoma Unit, Ophthalmology Department, Hospital Ramón y Cajal, Carretera Colmenar Viejo, km 9.1, Madrid E 28034, Spain. ... Nature.com Mitomycin C and Vinorelbine for second-line chemotherapy in NSCLC – a... - Nov 23, 2006 Single-agent therapy with Docetaxel or Pemetrexed is the current therapy of choice for second-line treatment in advanced non-small-cell lung cancer (NSCLC). ... Nature.com Capecitabine and mitomycin C as third-line therapy for patients with ... - Aug 9, 2005 Correspondence: Professor D Cunningham, Department of Medicine, The Royal Marsden Hospital, Downs Road, Sutton, Surrey SM2 5PT, UK. ... Nature.com Reduction of mitomycin C is catalysed by human recombinant NRH: … - Jul 31, 2006 NRH:Quinone Oxidoreductase 2 (NQO2) has been described as having no enzymatic activity with nicotinamide adenine dinucleotide (NADH) or NADPH as electron ... Nature.com Halozyme says Chemophases meets primary endpoint in Phase I/IIa trial - Jun 30, 2008 Based on the results, the Chemophase combination treatment of mitomycin plus the recombinant human hyaluronidase enzyme was 'well tolerated and appears safe ... Forbes … of trabeculectomy with intraoperative mitomycin-C between Asian … - Oct 14, 2005 Low-dose mitomycin C trabeculectomy in patients with advanced glaucoma. ... Outcomes of primary trabeculectomy with the use of adjunctive mitomycin. ... Nature.com … of the conjunctival flap from contact with mitomycin C during... - Jun 2, 2006 We declare that we have no financial or proprietary interest in any material, product or company mentioned in this paper. ... Nature.com Deep sclerectomy augmented with mitomycin C - Mar 4, 2005 Correspondence: N Anand, Department of Ophthalmology, Huddersfield Royal Infirmary, Lindley, Huddersfield HD3 3EA, UK. Tel: +44 1484 342526; ... Nature.com The structure-specific endonuclease Mus81–Eme1 promotes conversion … - Oct 12, 2006 Analysis of mitomycin C-induced DSB formation in wild-type, Ercc1 -/- and ... Cells were either untreated or incubated with 2.0 g/ml mitomycin C. (C) Time ... Nature.com Bladder Cancer - Medications - May 25, 2007 Mitomycin C is an antitumor antibiotic that interferes with the ... When administered directly into the bladder, mitomycin may help prevent the recurrence ... WebMD Mitomycin in PRK can affect endothelial cell count - Apr 18, 2005 WASHINGTON — Use of mitomycin-C in patients undergoing PRK can cause endothelial cell loss, as well as increased patient discomfort, according to Alberto J. ... OSN SuperSite Mitomycin (Systemic). - May 1, 2006 Mitomycin ( mye-toe-MYE-sin) belongs to the group of medicines known as antineoplastics. It is used to treat some kinds of cancer. ... Free with registration - USP DI-Volume II, Advice for the... - AccessMyLibrary.com Effect Of Mitomycin C On Anterior Urethral Stricture Recurrence After... - Jun 11, 2007 UroToday.com- Multiple variations to the procedure of the direct vision internal urethrotomy (DVIU) have been proposed to increase the efficacy of this ... Medical News Today - Medical News Today (press release) Topical mitomycin C was safe, effective for airway stenosis.(Pulmonary... - Dec 15, 2005 LOS ANGELES -- Topical mitomycin C sharply reduced recurrence rates in patients undergoing endoscopic treatment for airway stenosis, Joshua C. James, MD, ... Free with registration - Internal Medicine News - AccessMyLibrary.com … of Standard (0.02%) and Low Dose (0.002%) Mitomycin C in the … - Jan 1, 2008 To retrospectively compare the safety and efficacy of lower dose mitomycin C (MMC) (0.002%) to that of the standard dose (0.02%) in eyes treated with ... OSN SuperSite Low-dose mitomycin-C safe in treating, preventing haze associated... - Mar 18, 2006 Refractive surgeons can safely and effectively use a single application of low-dose mitomycin-C to treat or prevent corneal haze and scarring associated ... Ophthalmology Times Intraoperative use of mitomycin C in fibrous atresia of the external ... - Dec 1, 2005 The ability of mitomycin C to inhibit fibroblasts in vitro has prompted its use ... During the procedure, we applied I ml of mitomycin C (0.4 mg/ml)for 4 ... Free with registration - Ear, Nose and Throat Journal - AccessMyLibrary.com MyFox Lubbock | Mutamycin - Uses, Side Effects, Interactions,... - Mar 12, 2007 Mitomycin belongs to the group of cancer-fighting medications known as ... Mitomycin causes the death of cancer cells by interfering with their growth and ... myFOXlubbock.com Effect of Prophylactic and Therapeutic Mitomycin C on Corneal... - Jun 1, 2006 ...by Marcelo V. Netto, MD; Rajiv R. Mohan, PhD; Sunilima Sinha, MS; Ajay Sharma, PhD; Pankaj C. Gupta, MD; Steven E. Wilson, MD ... OSN SuperSite Article: Topical mitomycin C was safe, effective for airway stenosis.(... - Dec 15, 2005 Topical mitomycin C was safe, effective for airway stenosis.(Pulmonary Medicine) ... find Internal Medicine News articles. LOS ANGELES -- Topical mitomycin ... Pay-Per-View - Internal Medicine News - HighBeam Research Mitomycin C, BCG Comparable For High-Risk Bladder Cancer - May 8, 2007 A 10-year follow-up study of patients with high-risk bladder cancer shows that mitomycin C (MMC) and bacillus Calmette-Guérin (BCG) have similar effects on ... Renal and Urology News LASEK, epi-LASIK to remain niche procedures despite some advantages, … - Feb 20, 2008 ..."This is, in my opinion, the only potential benefit of these procedures: They minimize the risk of haze without the use of mitomycin-C, which is not such an ... OSN SuperSite Immediate Intravesical Mitomycin C After Bladder Tumor Resection Safe - Apr 4, 2006 ..."Many large studies have confirmed that administration of chemotherapy (usually mitomycin C) into the bladder within 6 hours of resection of a bladder ... UroToday International Journal … a Delivery System for Standardized Application of Mitomycin C in... - Sep 1, 2007 Mitomycin C contact surface area, amount absorbed, and amount released by each corneal light shield were reproducible. Uniform dimensions theoretically ... OSN SuperSite Mitomycin C aids corneal healing after photoablation - Sep 13, 2005 Lisbon, Portugal — Application of mitomycin C after PRK prevents the development of corneal haze and improves visual acuity. Ewa Mrukwa-Kominek, MD, ... Ophthalmology Times Bullous keratopathy possible after trabeculectomy with mitomycin-C - Jul 1, 2006 Two cases suggest a compromised endothelium and mitomycin use may lead to development of the complication after glaucoma surgery. by Jared Schultz ... OSN SuperSite Cancer of the anal canal in a patient with HIV - Aug 10, 2008 C) Combination of 5-FU and mitomycin-C concurrent with radiation therapy. ... Role of mitomycin in combination with fluorouracil and radiotherapy, ... HemOncToday Mitomycin C Plus Photodynamic Therapy Promising in Recurrent Bladder ... - Jul 1, 2005 NEW YORK JUL 01, 2005 (Reuters Health) - Instillation of mitomycin C followed by 5-aminolaevulinic acid-mediated photodynamic therapy (ALA-PDT) is safe and ... Cancerpage.com Immediate mitomycin C therapy post TURBT recommended - Mar 3, 2006 Administering mitomycin C, in theatre, immediately after transurethral bladder cancer resection (TURBT) is the "earliest and surest" prophylaxis against ... Medwire (subscription) Supergen Sells Select Non-Core Assets to Intas. - Apr 20, 2007 ...that it signed a definitive agreement to sell the rights to anticancer agents mitomycin and paclitaxel to Intas Pharmaceuticals Ltd. for $1.2 million. ... Free with registration - PR Newswire - AccessMyLibrary.com New research seeks methods to ease drawbacks of surface ablation - Jan 10, 2008 ...“Low-dose mitomycin 0.002% is statistically better than no mitomycin in ... “The duration of mitomycin is probably a little less important than the standard ... OSN SuperSite Intraoperative use of mitomycin C in fibrous atresia of the external ... - Dec 1, 2005 Abstract Introduction Occlusions and closures of the external auditory canal are rare and difficult to manage. (1) Either can occur as a congenital ... $4.95 - Ear, Nose and Throat Journal - ECNext Halozyme Therapeutics Completes Enrollment in Chemophase Phase I/ … - Sep 27, 2007 The multicenter, open-label, nonrandomized trial will evaluate multiple administrations of Chemophase along with the mitomycin, a widely used anticancer ... FDA news - FDA news (subscription) Adjuvant Mitomycin C Does Not Compensate For An Inadequate … - Jun 25, 2006 UroToday.com - Due to the measurable incidence of residual disease after TUR (approaching 35%) and pathologic understaging, repeat TUR is recommended for ... Medical News Today - Medical News Today (press release) PRK plus mitomycin-C useful approach after PKP: refractive errors … - Nov 15, 2005 Intraoperative use of mitomycin-C (MMC) with photorefractive keratectomy (PRK) is a safe and efficacious method for prophylaxis against haze in eyes with ... Free with registration - Ophthalmology Times - AccessMyLibrary.com Adjuvant Mitomycin C Does Not Compensate For An Inadequate … - Jun 21, 2006 BERKELEY, CA (UroToday.com) - Due to the measurable incidence of residual disease after TUR (approaching 35%) and pathologic understaging, repeat TUR is ... UroToday International Journal Report On Proposed Guidelines On Bladder Cancer For Non Muscle … - Jun 18, 2007 Specifically, the panel recommends that patients who present with a lesion have it resected, and consideration be given to peri-operative mitomycin with ... Medical News Today - Medical News Today (press release) Bladder Cancer; SIAC with mitomycin C used to treat gallbladder cancer - Sep 20, 2005 2005 SEP 20 - (NewsRx.com) -- Superselective intra-arterial chemotherapy (SIAC) with mitomycin C in gallbladder cancer was studied. ... Pay-Per-View - Life Science Weekly - Factiva, from Dow Jones Halozyme Therapeutics Initiates Chemophase Phase I/IIa Clinical Trial... - Apr 26, 2006 The observed plasma levels of mitomycin were less than 1/40th of the levels reported to be predictive of suppression of white blood cell production. ... Free with registration - PR Newswire - AccessMyLibrary.com Experimental Therapy Not More Effective Than Standard Treatment For … - Apr 17, 2008 The 5-year disease-free survival rate was 60 percent in the mitomycin-based group and 54 percent in the cisplatin-based group. The 5-year overall survival ... newswise.com … Cancer; Intra-arterial chemotherapy with mitomycin C in gallbladder... - Sep 27, 2005 ..."There is only limited and somewhat controversial information available on hepatic artery infusion of cytotoxic agents in gallbladder cancer. ... Pay-Per-View - Life Science Weekly - Factiva, from Dow Jones AUA 2006 - ABST [832] Optimized intravesical mitomycin C treatment... - May 21, 2006 AUA 2006 - ABST [832] Optimized intravesical mitomycin C treatment for superficial bladder cancer: long-term follow-up. Jessie L Au*, Columbus, OH; ... UroToday International Journal GEI First in World to Conduct Successful Pilot Study of 'Ologen... - Aug 11, 2008 In the conventional method 'Phaco-Trab with Mitomycin-C', Mitomycin-C is used as a Chemotherapeutic Agent. Its purpose is to maintain the surgically created ... 24-7pressrelease.com Post-Operative Instillation Of Intravesical Mitomycin C Is Safe - Mar 10, 2006 BERKELEY, CA (UroToday.com) - Recurrence rates following transurethral resection of bladder tumors (TURBT) are significant. This can be due to reseeding of ... UroToday International Journal Post-Operative Instillation Of Intravesical Mitomycin C Is Safe - Mar 11, 2006 UroToday.com - Recurrence rates following transurethral resection of bladder tumors (TURBT) are significant. This can be due to reseeding of tumor cells at ... Medical News Today - Medical News Today (press release) Cancer Therapy; Capecitabine and mitomycin C exhibit efficacy as... - Oct 25, 2005 2005 OCT 25 - (NewsRx.com) -- Capecitabine and mitomycin C (MMC) exhibit efficacy as third-line therapy for metastatic colorectal cancer resistant to ... Pay-Per-View - Life Science Weekly - Factiva, from Dow Jones GEI Team presents Success Results of Revolutionary Pilot Study at... - Jul 11, 2008 In the conventional method 'Phaco-Trab with Mitomycin-C', Mitomycin-C is used as a Chemotherapeutic Agent. Its purpose is to maintain the surgically created ... exchange4media.com Halozyme Completes Enrollment in Bladder Cancer Trial - Mar 7, 2006 All of these patients may be potential candidates for Chemophase in the event it is approved as first-line treatment with mitomycin. ... RedOrbit Cancer Therapy; Capecitabine and mitomycin C exhibit efficacy as... - Oct 25, 2005 2005 OCT 25 - (NewsRx.com) -- Capecitabine and mitomycin C (MMC) exhibit efficacy as third-line therapy for metastatic colorectal cancer resistant to ... Pay-Per-View - Cancer Weekly - Factiva, from Dow Jones Cancer Therapy; Capecitabine and mitomycin C exhibit efficacy as... - Oct 24, 2005 2005 OCT 24 - (NewsRx.com) -- Capecitabine and mitomycin C (MMC) exhibit efficacy as third-line therapy for metastatic colorectal cancer resistant to ... Pay-Per-View - Health & Medicine Week - Factiva, from Dow Jones Cancer Therapy; Capecitabine and mitomycin C exhibit efficacy as... - Oct 25, 2005 2005 OCT 25 - (NewsRx.com) -- Capecitabine and mitomycin C (MMC) exhibit efficacy as third-line therapy for metastatic colorectal cancer resistant to ... Pay-Per-View - Science Letter - Factiva, from Dow Jones Combined modality chemoradiation in elderly oesophageal cancer … - Jan 8, 2007 We present a single institution experience with 5-FU, mitomycin-C based ... We opted to employ the combination of 5-FU and mitomycin with radiation, ... Nature.com Halozyme Therapeutics initiates chemophase Phase I clinical trial for... - Oct 27, 2005 The objectives of the study are to determine the safety, tolerability and pharmacokinetics of Chemophase administered intravesically with mitomycin. ... Free with registration - Asia Africa Intelligence Wire - AccessMyLibrary.com Halozyme Therapeutics receives FDA clearance to initiate Chemophase … - Aug 11, 2005 The initial clinical protocol under this IND is a Phase I study designed to evaluate a single intravesical administration of Chemophase along with mitomycin ... Pay-Per-View - Company Reports - Factiva, from Dow Jones Surgeries for near-sightedness compared - Apr 24, 2006 What these studies didn't address is the use of mitomycin C, an anti-scar drug which can be used to correct this problem. This review reveals useful ... HealthandAge.com Proteomic identification of p53-dependent protein phosphorylation - Apr 28, 2008 We first confirmed that treatment with the DNA-damaging agent mitomycin C (MMC) ... Induction and phosphorylation of p53 and apoptosis in mitomycin C ... Nature.com … recurrence rates in T1 bladder tumors, even after intravesical... - Jul 10, 2006 To compare the outcomes of repeat TUR of the bladder plus intravesical mitomycin C with the outcomes of single TUR plus mitomycin C, in patients with newly ... Nature.com Press Release: Halozyme Therapeutics Completes Enrollment in … - Sep 25, 2007 The objectives of the study included determining the maximum tolerated dose (MTD) and dose-limiting toxicities, if any, of escalating doses of mitomycin and ... Pay-Per-View - PR Newswire - HighBeam Research Pterygium treatment using 5-FU as adjuvant treatment compared to … - Jun 16, 2006 Both mitomycin-C and 5-FU have been shown to cause a reduction in recurrence ... 10 Mitomycin C is reported 11 to be more effective in preventing pterygium ... Nature.com Bladder Cancer Treatment (PDQ®) - Stage 0 Bladder Cancer - May 16, 2008 15] One study that compared mitomycin with interferon-a-2b showed an improved outcome with mitomycin, even though interferon was better tolerated.[16] WebMD Press Release: Halozyme Therapeutics Presents Preclinical and Phase I... - Apr 4, 2006 The objectives ... superficial bladder cancer in the U ... mitomycin. ... The objectives ... mitomycin. About Halozyme Therapeutics, Inc. Halozyme ... ... Pay-Per-View - PR Newswire - HighBeam Research Penetration of topically applied levofloxacin into eyes with thin... - Jul 6, 2005 Various antifibrotic medications, such as mitomycin C (MMC) and 5-fluorouracil ... Intermediate-term outcome of variable dose mitomycin C filtering surgery. ... Nature.com Early bleb leak after trabeculectomy and prognosis for bleb failure - May 23, 2008 Cellulose sponges soaked in mitomycin-C at concentrations of 0.1–0.4 mg/l ... Trabeculectomy with augmented mitomycin C application under the scleral flap. ... Nature.com Myriad Genetics Sponsors Clinical Trial in Pancreatic Cancer - Oct 24, 2006 Mitomycin-C is one member of an important class of DNA damaging agents used to treat ... When mitomycin-C damages the DNA in a patient's cancer cells, ... Genetic Engineering News - Genetic Engineering News (press release) Halozyme Therapeutics Reports First Quarter 2006 Financial Results. - May 10, 2006 The objectives of the study were to determine the safety, tolerability and pharmacokinetics of Chemophase administered intravesically with mitomycin. ... $4.95 - PR Newswire - ECNext Press Release: Halozyme Therapeutics Reports First Quarter 2006 … - May 10, 2006 The objectives of the study were to determine the safety, tolerability and pharmacokinetics of Chemophase administered intravesically with mitomycin. ... Pay-Per-View - PR Newswire - HighBeam Research Press Release: Halozyme Therapeutics Begins Phase 2 Clinical Trial of... - Nov 3, 2008 Chemophase ... treatment with mitomycin. About Halozyme Therapeutics, Inc. Halozyme is ... "By initiating Phase I enrollment and dosing ... with mitomycin. ... Pay-Per-View - PR Newswire - HighBeam Research Press Release: Halozyme Therapeutics Completes Enrollment of … - Mar 6, 2006 The Company ... mitomycin in patients with superficial bladder cancer. This dose ... enrolled 27 patients with superficial bladder cancer. The ... ... Pay-Per-View - PR Newswire - HighBeam Research MMC assists in preventing recurrence of neoplasia - Jul 1, 2008 HONG KONG — The use of adjunctive mitomycin-C in addition to excision provides the best ... "Mitomycin-C treatment following surgical excision of localized ... OSN SuperSite University of Bonn, Germany; Findings from University of Bonn,... - Nov 14, 2006 This effect was comparable to exposition to mitomycin. Distilled water and mitomycin have comparable in vitro effects in bladder cancer cells," wrote G. ... Pay-Per-View - Life Science Weekly - Factiva, from Dow Jones New approach to trabeculectomy preserves episcleral tissue - May 25, 2008 Mitomycin is then applied to the under surface of the flap and the scleral bed for 4 minutes. Paracentesis is done at 2 o'clock in the clear cornea, ... OSN SuperSite Calreticulin exposure increases cancer immunogenicity - Feb 1, 2007 Tautomycin/mitomycin C was more effective than anthracyclines in the CT26 model, suggesting that combining more effective phosphatase 1 inhibitors with ... Nature.com … prevent late-onset bleb leakage after trabeculectomy with mitomycin... - Dec 15, 2006 Histopathologic effects of mitomycin C after trabeculectomy in human glaucomatous ... Bleb-related endophthalmitis after trabeculectomy with mitomycin C. ... Nature.com Long-term intraocular pressure control of eyes that developed … - Apr 1, 2005 Results of medical management and mitomycin C-augmented excisional bleb revision ... Slit-lamp needle revision of failed filtering blebs using mitomycin C. ... Nature.com The structure-specific endonuclease Mus81–Eme1 promotes conversion … - Oct 12, 2006 ...(C) Comparison of mitomycin C sensitivity of wild-type, Mus81 -/- , Rad54 -/- and Mus81 ... (D) Analysis of mitomycin C-induced DSB formation in wild-type, ... Nature.com Survival from bladder cancer in England and Wales up to 2001 - Sep 23, 2008 Perioperative intravesical chemotherapy (mitomycin or epirubicin) is effective in reducing tumour recurrence and is considered the standard of care ... Nature.com Chemotherapy for metastatic NSCLC: current status and future direction - Feb 10, 2005 The mitomycin, ifosfamide and cisplatin (MIC) regimen is commonly used in ... Patients in the MIC arm received mitomycin 6 mg/m 2 , ifosfamide 3 g/m 2 and ... Nature.com Tips offered for safe, effective antimetabolite use - Feb 22, 2006 In addition, in order to create a more diffuse posterior bleb, the flap should be fornix-based, not limbus-based, and the intraoperative mitomycin-C should ... Ophthalmology Times Corneal refractive surgery aids visual rehabilitation in PKP eyes.(LAS... - Apr 15, 2005 That experience combined with the advent of mitomycin-C as an adjunct to PRK ... In those eyes, 0.02% mitomycin-C was applied to the corneal stromal bed for ... Free with registration - Ophthalmology Times - AccessMyLibrary.com Success of trabeculotomy in patients with congenital glaucoma... - Jan 6, 2006 There have been few reports on the use of Mitomycin-C (MMC) during trabeculectomy in ... Surgical results and complications of Mitomycin-C augmented ... Nature.com Patient Selection; Scoring system predicted clinical response and … - Nov 21, 2005 ..."This is a prospective, phase III study aimed to evaluate the effect of concurrent 5-fluorouracil, mitomycin C, and radiation with or without brachytherapy ... Pay-Per-View - OBGYN & Reproduction Week - Factiva, from Dow Jones Halozyme Therapeutics to Present Preclinical, Toxicology and Phase I ... - Mar 28, 2006 Pre-clinical data on the pharmacology and toxicology of rHuPH20, a recombinant human hyaluronidase, with mitomycin will be presented along with clinical ... $4.95 - PR Newswire - ECNext HALOZYME BEGINS BLADDER CANCER TRIAL - May 2, 2006 ...used anticancer drug mitomycin in patients with superficial bladder cancer, ... initial phase I trial of single-administration Chemophase and mitomycin. ... Pay-Per-View - FDAnews Drug Pipeline Alert - Factiva, from Dow Jones Methylation-induced silencing of ASC and the effect of expressed ASC... - May 31, 2005 At 24 h after infection, the cells were treated with mitomycin C (MMC, 10 g/ml), actinomycin D (Act D, 100 ng/ml), doxorubicin (Dox, 600 ng/ml), ... Nature.com Phase III study of 5FU, etoposide and leucovorin (FELV) compared to … - Mar 3, 2005 Harvey JH, Smith FP, Schein PS (1984) 5-Fluorouracil, mitomycin, and doxorubicin (FAM) in carcinoma of the biliary tract. J Clin Oncol 2: 1245–1248 | PubMed ... Nature.com Study finds MMC useful adjunct in LASEK on thin corneas - Nov 10, 2007 NEW ORLEANS — LASEK performed in myopes with thin corneas yielded long-term stable results with the use of mitomycin-C, according to a study presented here. ... OSN SuperSite Managing malignant conjunctival lesions - Apr 16, 2007 Other options are cryotherapy, application of mitomycin C, or a combination therapy. With diffuse lesions, multiple biopsies should be performed. ... Ophthalmology Times Halozyme Therapeutics Reports Second Quarter 2006 Financial Results. - Aug 10, 2006 ...designed to evaluate multiple intravesical (in the bladder) administrations of Chemophase along with the widely-used anticancer drug mitomycin, or MMC, ... Free with registration - PR Newswire - AccessMyLibrary.com Halozyme Therapeutics Presents Preclinical and Phase I … - Apr 4, 2006 ..."Achieving effective penetration into residual tumor without elevating systemic mitomycin levels could potentially enhance efficacy without increasing risk ... Free with registration - PR Newswire - AccessMyLibrary.com Deep sclerectomy, trabeculectomy effectively lower IOP: comparative … - Sep 1, 2005 This eye was treated with trabeculectomy supplemented with mitomycin C. ... These two then underwent trabeculectomy with mitomycin C. Of the remaining 39 ... Free with registration - Ophthalmology Times - AccessMyLibrary.com Post-LASIK ectasia management circumvents need for keratoplasty: … - Oct 1, 2007 Mitomycin 0.02% was applied to the ablated stromal bed for 30 seconds to minimize keratocyte-activated corneal haze postoperatively. ... Free with registration - Ophthalmology Times - AccessMyLibrary.com Chemoembolization Useful for Palliative Treatment of Liver Metastases - Dec 24, 2008 The local chemotherapy protocol consisted of mitomycin C alone (n = 243), mitomycin C with gemcitabine (n = 153), or mitomycin C with irinotecan (n = 67). ... Medscape Flap architecture, MMC play key roles in trabeculectomy - Jul 3, 2008 HONG KONG — Both flap architecture and mitomycin-C significantly affect bleb ... "Mitomycin-C actually can affect the ciliary body and can actually create ... OSN SuperSite 6 When medical therapy fails: surgical options for glaucoma management... - Oct 15, 2006 One concern is that anti-metabolites, particularly mitomycin, have been associated with a higher risk for late wound leak, blebitis and endophthalmitis. ... Free with registration - Review of Optometry - AccessMyLibrary.com A study of bone marrow failure syndrome in children.(ORIGINAL … - Jan 1, 2008 Chromosomal study using Mitomycin-C (MMC) was done to diagnose patients of Fanconi ... Mitomycin-C was added in concentration of 40 ng/mL of media for the ... Free with registration - Indian Journal of Medical Sciences - AccessMyLibrary.com Combined corneal scar excision, PRK surgery seeks unaided … - Jun 10, 2008 Application of mitomycin-C 0.02% to the central cornea. Immediate postoperative view of the cornea after combined mechanical removal of the corneal scar and ... OSN SuperSite Brand Names/Synonyms: Mitomycin is also known by the following brand names and/or synonymsAmetycin; Ametycine; CCRIS 414; HSDB 3239; MITOMYCIN; MMC; MUTAMYCIN; Mit-C; Mitamycin; Mito-C; Mitocin-C; Mitomycin; Mitomycin C; Mitomycin C/Nacl; Mitomycin [Usan:Ban:Inn]; Mitomycin-C; Mitomycinum; Mitomycinum C; Mitomycyna C [Polish]; Mitozytrex; Muamycin; Mutamycin; Mytomycin; Mytozytrex; Rcra Waste No. U010; Rcra Waste Number U010 Drug Category: Mitomycin is categorized under the following by the FDA: Antibiotics; Alkylating Agents; Antineoplastic Agents; Cross-Linking Reagents; Nucleic Acid Synthesis Inhibitors; ATC:L01DC03 Dosage Forms: POWDER FOR SOLUTION Absorption: Erratic Interactions: [an error occurred while processing this directive] Chemical IUPAC Name: (1aS,8S,8aR,8bS)-6-amino-8a-methoxy-5-methyl-4,7-dioxo-1,1a,2,4,7,8,8a,8b-octahydroazirino[2',3':3,4]pyrrolo[1,2-a]indol-8-yl]methyl carbamate |
|
Health Home | Conditions | Cancer | Medications | Surgery | Vaccines The Cancer News Network
COPYRIGHT 2009 CANCERNEWSNETWORK | Privacy |