|
 |
MitoxantroneThis page contains recent news articles, when available, and an overview of Mitoxantrone but does not offer medical advice. You should contact your physician with regard to any health issues or concerns.Overview: Mitoxantrone (when available) Mitoxantrone has been shown in vitro to inhibit B cell, T cell, and macrophage proliferation and impair antigen presentation, as well as the secretion of interferon gamma, TNFa, and IL-2. For the treatment of secondary (chronic) progressive, progressive relapsing, or worsening relapsing-remitting multiple sclerosis Mechanism Of Action: Mitoxantrone, a DNA-reactive agent that intercalates into deoxyribonucleic acid (DNA) through hydrogen bonding, causes crosslinks and strand breaks. Mitoxantrone also interferes with ribonucleic acid (RNA) and is a potent inhibitor of topoisomerase II, an enzyme responsible for uncoiling and repairing damaged DNA. It has a cytocidal effect on both proliferating and nonproliferating cultured human cells, suggesting lack of cell cycle phase specificity. News Articles on Mitoxantrone Zevalin® (Ibritumomab Tiuxetan) Demonstrated Activity in Several ... - Dec 11, 2009 Bologna, Italy Introduction: In 2008 we published a multicenter non-randomized phase II trial of fludarabine and mitoxantrone plus 90Y-IT in untreated ... Benzinga Genzyme's Mozobil shows promise in chemosensitization - Dec 9, 2009 The patients were given Mozobil, and four hours later received the AML combination chemotherapy regimen mitoxantrone, etoposide, and cytarabine (MEC). ... pharmabiz.com Quando la cura costa cara - Dec 10, 2009 Io purtroppo mi sono rovinato perché ero seguito da un ospedale, camminavo con un bastone, mi hanno fatto il mitoxantrone; dopo due infusioni, ... Associazione Luca Coscioni Preop Chemotherapy Could Aid Prostate Cancer Treatment - Oct 22, 2009 ORLANDO—Preoperative combination chemotherapy with docetaxel and mitoxantrone appears to be safe, and about 50% of men with high-risk localized prostate ... Renal and Urology News IPF 2009 - Management of castrate resistant prostate cancer - Session Highlights - Oct 25, 2009 Two major randomized trials found docetaxel every 3 weeks provided 20% improvement in survival (2.6 months) compared to mitoxantrone + prednisone. ... UroToday BUYINS.NET: FFIV, PTV, OSIP, RJF, CFR, DST Expected To Be Higher After ... - Oct 19, 2009 The company also offers Novantrone, a mitoxantrone for injection concentrate. OSI Pharmaceuticalsa products in Phase I clinical trials include OSI-906, ... Trading Markets (press release) New Oral Agent, Tasquinimod, May Have Activity in Prostate Cancer - Oct 26, 2009 Chemotherapy agents for patients with HRPC include: Taxotere® (docetaxel), Emcyt® (estramustine), Novantrone® (mitoxantrone), ixabepilone, ... Cancer Consultants Comparing notes: UK's cancer leaders discuss the latest advances - Oct 28, 2009 Also highlighted were results from SWOG S9921, a trial of adjuvant combined androgen deprivation with or without mitoxantrone chemotherapy in patients with ... Pharmafocus … Dabur Pharma gets US FDA approval to market generic Mitoxantrone - May 21, 2008 ...for the abbreviated new drug application (ANDA) to market the generic version of EMD Serono's Novantrone or Mitoxantrone Hydrochloride injection. ... Forbes Mitoxantrone for multiple sclerosis - Feb 28, 2008 Mitoxantrone (Novantrone) is an immunosuppressant, a type of medication that reduces the activity of the immune system. It has been used to treat leukemia ... WebMD Prostate Cancer Trial Halted Due to 3 Cases of Leukemia - Jan 19, 2007 ..."The initial studies of mitoxantrone were done in men with end-stage prostate ... Mitoxantrone has been approved for use in prostate cancer as well as in ... Washington Post … acute promyelocytic leukemia following mitoxantrone treatment in... - Oct 19, 2006 Mitoxantrone, a DNA topoisomerase II inhibitor used in cancer therapy, was the first ... A recent report suggests that mitoxantrone induces in vitro ... Nature.com US advice on heart tests for mitoxantrone - Jul 25, 2008 The Food and Drug Administration, which checks the safety of drugs in the United States, advises that you should have one of the following tests on your ... guardian.co.uk High-dose cytarabine and mitoxantrone in consolidation therapy for... - Apr 21, 2005 Correspondence: Dr RF Schlenk, Department of Internal Medicine III, University Hospital of Ulm, Robert-Koch-Strasse 8, 89081 Ulm, Germany. ... Nature.com … Multiple Sclerosis A combination between Mitoxantrone anti-cancer... - Jul 22, 2006 Mitoxantrone is an extremely powerful anti-cancer drug that is not recommended to be taken for long periods of time, as it can become highly toxic for the ... Softpedia … of the effectiveness of docetaxel and mitoxantrone for the... - Apr 28, 2006 A scoping search identified a trial of docetaxel plus prednisone vs mitoxantrone plus prednisone, but did not identify any trials comparing docetaxel plus ... Nature.com Fludarabine, mitoxantrone and dexamethasone as first-line treatment... - May 24, 2007 There is currently no consensus on the optimal treatment of T-cell large granular lymphocyte (T-LGL) leukemia. Conventional treatment including oral ... Nature.com Paclitaxel and carboplatin versus mitoxantrone: lessons of an … - May 9, 2006 Cabrespine A et al. (2006) Randomized phase II study comparing paclitaxel and carboplatin versus mitoxantrone in patients with hormone-refractory prostate ... Nature.com Wales News What is Mitoxantrone? - Nov 1, 2005 Mitoxantrone is primarily used as a chemotherapy drug for patients with leukaemia, but it has been licensed in the US as a means of slowing down the ... WalesOnline Learn about Mitoxantrone Injection from Consumer Reports Health. - Jan 4, 2008 Mitoxantrone should be given only under the supervision of a doctor with experience in the use of ... Full Alert. Mitoxantrone injection is used to decrease ... consumerreports.org … After Maximum Cumulative Mitoxantrone Dosing: Presented at - Oct 4, 2005 Mitoxantrone is the main treatment for aggressive multiple sclerosis (MS) ... However, mitoxantrone is limited to a maximal cumulative dose of 140 mg/m 2 . ... DG News Mitoxantrone as Induction Followed by Interferon Beta-1b Versus … - Oct 18, 2007 By Chris Berrie. PRAGUE, CZECH REPUBLIC -- October 18, 2007 -- Mitoxantrone induction in combination with methylprednisone prior to interferon beta-1b ... DG News What is the current status of second-line chemotherapy for castration... - Sep 9, 2008 Mitoxantrone plus prednisone is frequently used in this setting. The retrospective analysis by Berthold et al. of mitoxantrone after first-line docetaxel in ... Nature.com Mayne Announces FDA Approval of Mitoxantrone - Apr 11, 2006 PARAMUS, NJ, April 11 /PRNewswire/ -- Mayne Pharma (USA) Inc. announces that the US Food and Drug Administration (FDA) has granted final approval for the ... RedOrbit Multiple Sclerosis; Clinical study of mitoxantrone is in progress to... - Mar 7, 2005 2005 MAR 7 - (NewsRx.com & NewsRx.net) -- A recent report focused on safety considerations of mitoxantrone treatment of multiple sclerosis. ... Pay-Per-View - Pain & Central Nervous System Week - Factiva, from Dow Jones Mitoxantrone Can Extend Time to Disease Progression in Worsening … - May 7, 2007 By Maria Bishop. BOSTON, MA -- May 7, 2007 -- The results of the Registry to Evaluate Novantrone Effects in Worsening MS (RENEW) study continue to ... DG News The blend of drugs that can 'stop MS in its tracks' - Jul 24, 2006 It involves a limited course of the chemotherapy drug Mitoxantrone, ... Mitoxantrone appears to work in MS sufferers by suppressing the immune system and ... Daily Mail Multiple Sclerosis; Clinical study of mitoxantrone is in progress to... - Mar 8, 2005 2005 MAR 8 - (NewsRx.com & NewsRx.net) -- A recent report focused on safety considerations of mitoxantrone treatment of multiple sclerosis. ... Pay-Per-View - Life Science Weekly - Factiva, from Dow Jones Do estroprogestinic hormones protect against chemotherapy-induced … - Oct 6, 2008 This commentary discusses a paper by Cocco et al. that addresses the treatment of multiple sclerosis (MS) with the drug mitoxantrone in women of ... Nature.com Novantrone Linked to Cardiotoxicity and AML in MS and Cancer Patients - May 25, 2005 Postmarketing reports have shown that mitoxantrone is associated with a risk of ... Mitoxantrone should not be administered to MS patients who demonstrate a ... Medscape … : Watch Cardiac Function in MS Patients During and After Mitoxantron... - Jul 29, 2008 In March 2005, the labeling for mitoxantrone was changed to recommend that patients with left ventricular ejection fraction (LVEF) be evaluated before ... DG News Long-Term Follow-Up Data of Mitoxantrone in Multiple Sclerosis Show … - Apr 7, 2006 By Claire Sowerbutt. SAN DIEGO, CA -- April 7, 2006 -- Five-year cardiac and haematological data from a large cohort of multiple sclerosis (MS) patients ... DG News … Use of estramustine, vinorelbine, and mitoxantrone for hormone... - Nov 29, 2005 The treatment schedule consisted of estramustine capsules (140 mg 3 times daily on days 1 to 3 and days 8 to 10 per os), intravenous mitoxantrone (12 mg/m2 ... Pay-Per-View - Life Science Weekly - Factiva, from Dow Jones Mitoxantrone Injection Side Effects from Consumer Reports Health. - Jan 4, 2008 Mitoxantrone should be given only under the supervision of a doctor with experience in the use of ... Full Alert. Mitoxantrone should be given only under ... consumerreports.org … Pharmaceutical Partners receives US FDA approval for Mitoxantrone - May 11, 2006 According to IMS, sales in 2005 of mitoxantrone in the United States exceeded $76 million. APP expects to commence marketing mitoxantrone immediately. ... Pay-Per-View - Biotech Business Week - Factiva, from Dow Jones Novacea Presents New Evidence That Its AQ4N Prodrug Candidate … - Apr 17, 2007 ..."The study demonstrates that mitoxantrone alone has limited drug penetration ... However, when AQ4N is combined with mitoxantrone, AQ4N is able to permeate ... Genetic Engineering News - Genetic Engineering News (press release) Docetaxel chemotherapy remains the standard of care in castration- … - May 5, 2008 Contemporary clinical trials with mitoxantrone and docetaxel have reversed this ... A randomized trial showed that mitoxantrone combined with low-dose ... Nature.com Real-Life Mitoxantrone (Novantrone) Study Confirms Efficacy, Safety... - Oct 3, 2005 By Bruce Sylvester. THESSALONIKI, GREECE -- October 3, 2005 -- A real-life, postapproval study of mitoxantrone (Novantrone) confirms the drug's efficacy as ... DG News Safety and Tolerability of Mitoxantrone for Worsening Multiple... - Oct 2, 2006 By Bruce Sylvester. MADRID, SPAIN -- October 2, 2006 -- Researchers report that the safety and tolerability of Novantrone (mitoxantrone) in long-term ... DG News How to take Mitoxantrone Injection from Consumer Reports Health. - Jan 4, 2008 Mitoxantrone should be given only under the supervision of a doctor with experience in the use of ... Full Alert. tell your doctor and pharmacist if you are ... consumerreports.org Bedford Laboratories(TM) to Begin Shipping Mitoxantrone Injection USP. - Apr 11, 2006 BEDFORD, Ohio, April 11 /PRNewswire/ -- Bedford Laboratories(TM), a division of Ben Venue Laboratories Inc., has announced that it began shipping ... $4.95 - PR Newswire - ECNext Treatment with COPAXONE(R) Plus Minocycline Showed Substantial … - May 4, 2007 COPAXONE([R]) has shown efficacy and safety both in combination with intravenous steroids and after induction with the immunosuppressant mitoxantrone; ... Free with registration - Business Wire - AccessMyLibrary.com Multiple Sclerosis; Clinical study of mitoxantrone is in progress to... - Mar 11, 2005 2005 MAR 11 - (NewsRx.com & NewsRx.net) -- A recent report focused on safety considerations of mitoxantrone treatment of multiple sclerosis. ... Pay-Per-View - Drug Week - Factiva, from Dow Jones A new drug improves long term survival for mantle cell lymphoma - Jul 2, 2007 The usual treatment is MCP(mitoxantrone, chlorambucil, and prednisolone), a type of chemotherapy. The Journal of Clinical Oncology found that by adding ... TopCancerNews.com Positive Phase 2 Prostate Cancer results with YM BioSciences' Lead … - Oct 14, 2005 The paper reported that the prostate specific antigen (PSA) decrease and reduction of symptoms observed with tesmilifene plus mitoxantrone/prednisone ... DG News Docetaxel Plus Prednisone Versus Mitoxantrone Plus Prednisone for … - Jan 4, 2008 To preliminarily investigate the efficacy of docetaxel plus prednisone and mitoxantrone plus prednisone for treating metastatic hormone-refractory prostate ... UroToday International Journal How It Works - Nov 30, 2006 Mitoxantrone belongs to a group of medications that interfere with the growth of the ... Mitoxantrone is used to treat acute myelogenous leukemia (AML) and ... WebMD OncoGenex Reports That Low Serum Clusterin Levels Were Predictive of ... - Jun 2, 2008 Median survival has been estimated at 11.4 months in the mitoxantrone plus OGX-011 group and 14.7 months in the docetaxel plus OGX-011 group. ... RedOrbit ECTRIMS 2006 - Diagnosis and Monitoring of Multiple Sclerosis - Nov 21, 2006 Mitoxantrone is approved for the treatment of worsening ... Therefore, mitoxantrone favorably reduced the rate of new T1-hypodense lesion volume and reduced ... Medscape Publication on Pixantrone Preclinical Studies Demonstrates Reduced … - Jun 26, 2007 The studies compared the cardiac side effects of equiactive doses of pixantrone to doxorubicin and mitoxantrone in mice pre-treated with a cardiotoxic dose ... Free with registration - PR Newswire - AccessMyLibrary.com Randomized trial of two therapies for acute lymphocytic leukemia... - May 12, 2005 Patients treated with cytarabine plus high-dose mitoxantrone appeared to have a survival advantage at three, four, and five years. ... PsychCentral.com OncoGenex Technologies Inc. Reports Lead Drug Candidate OGX-011 … - Feb 18, 2008 ..."These data show that the combination of OGX-011 with docetaxel or mitoxantrone may improve treatment outcomes in second-line prostate cancer," said Dr. ... Lifescience-online Teva Announces Approval of Mitoxantrone Hydrochloride Injection USP - Apr 12, 2006 Teva Pharmaceutical Industries Ltd. (Nasdaq: TEVA) announced today that the US Food and Drug Administration has granted final approval for the Company's ... Genetic Engineering News - Genetic Engineering News (press release) Press Release: Publication on Pixantrone Preclinical Studies … - Jun 26, 2007 Publication on Pixantrone Preclinical Studies Demonstrates Reduced Cardiotoxicity Compared to Equiactive Doses of Doxorubicin and Mitoxantrone. from PR ... Pay-Per-View - PR Newswire - HighBeam Research Press Release: Fludarabine, Mitoxantrone and Zevalin(R) Produces 96% ... - Mar 17, 2008 Fludarabine, Mitoxantrone and Zevalin(R) Produces 96% Complete Remission Rate in First-Line Treatment of Patients with Follicular Non-Hodgkin's Lymphoma. Pay-Per-View - PR Newswire - HighBeam Research drug delivery system, nanoparticle-encapsulated mitoxantrone, NanoDel... - Aug 1, 2005 NanoDel is utilizing its proprietary polymeric nanoparticle drug delivery technology to develop a formulation of mitoxantrone, for the potential treatment ... Pay-Per-View - R & D Focus Drug News - Factiva, from Dow Jones … Announces FDA Approval of Mitoxantrone. - PR Newswire | HighBeam … - Apr 11, 2006 Mayne Announces FDA Approval of Mitoxantrone. from PR Newswire. Highbeam Research – FREE Trial. Pay-Per-View - PR Newswire - HighBeam Research Radioimmunotherapy After Chemotherapy Effective for Non-Hodgkin … - Mar 13, 2008 The researchers aimed to assess the efficacy and safety of fludarabine (Fludar) and mitoxantrone (Novantrone) followed by radioimmunotherapy in untreated ... MedPage Today Docetaxel Plus Prednisone or Mitoxantrone Plus Prednisone for … - Jan 25, 2008 The TAX 327 study compared docetaxel administered every 3 weeks (D3), weekly docetaxel (D1), and mitoxantrone (M), each with prednisone (P), ... UroToday International Journal Docetaxel Plus Prednisone Or Mitoxantrone Plus Prednisone For … - Jan 20, 2008 UroToday.com- The TAX 327 study was reported in 2004 and evaluated patients with hormone-refractory prostate cancer (HRPC) in three treatment arms; ... Medical News Today - Medical News Today (press release) √ Docetaxel Plus Prednisone or Mitoxantrone Plus Prednisone for … - Jan 17, 2008 BERKELEY, CA (UroToday.com) - The TAX 327 study was reported in 2004 and evaluated patients with hormone-refractory prostate cancer (HRPC) in three ... UroToday International Journal … Laboratories(TM) to Begin Shipping Mitoxantrone Injection USP. -... - Apr 11, 2006 Bedford Laboratories(TM) to Begin Shipping Mitoxantrone Injection USP. from PR Newswire. Highbeam Research – FREE Trial. Pay-Per-View - PR Newswire - HighBeam Research Randomized Phase 2 Study of IMC-A12 and IMC-1121B for Advanced … - Aug 26, 2008 IMC-A12 and IMC-1121B are administered weekly, whereas mitoxantrone is administered every three weeks with oral daily prednisone. ... Lifescience-online Wales News MS sufferer battles drugs ban - Nov 1, 2005 But if he is to benefit from mitoxantrone, he must be prescribed it while he can ... "Mitoxantrone is licensed as a chemotherapy treatment for some types of ... WalesOnline Pixantrone Produces High Rate (77 percent) of Complete Tumor … - May 16, 2006 This trial examines the safety and potential efficacy for pixantrone when substituted for mitoxantrone in the FND-R regimen (fludarabine, mitoxantrone, ... Free with registration - PR Newswire - AccessMyLibrary.com OncoGenex, Isis report Phase II success - Feb 15, 2008 OncoGenex and collaborator Isis Pharmaceuticals say that in a Phase II trial, OGX-011, in combination with either docetaxel or mitoxantrone, ... FierceBiotech MS treatment in pill form trialled - Jun 20, 2008 Drugs currently available for relapse-remitting MS include glatiramer acetate, interferon, natalizumab and mitoxantrone. However, they all have to be ... Nursing in Practice Orange County Business Journal Online - May 9, 2008 The drugs are ondansetron, which treats nausea and vomiting, and cancer treatments carboplatin, fludarabine and mitoxantrone. ... Orange County Business Journal - Orange County Business Journal Drug Combo Shown to Reverse Multiple Sclerosis - Sep 19, 2006 Mitoxantrone is an anti-cancer drug so powerful that it is potentially toxic ... Patients were first given a limited course of mitoxantrone, before being ... FOXNews Behind the Headlines: Can 'miracle' therapy reverse MS?(Multiple … - Aug 4, 2006 The two drugs used in the study were mitoxantrone, which is normally used to ... They gave mitoxantrone to patients who had had MS for five or fewer years ... Free with registration - GP - AccessMyLibrary.com FDA Safety Labeling Changes: Novantrone, Mevacor, Nitro-Dur - Jul 6, 2005 Postmarketing reports have revealed that mitoxantrone is associated with a risk of ... Mitoxantrone should not be administered in patients demonstrating a ... Medscape Very Active Multiple Sclerosis Patients Benefited from COPAXONE(R) … - Sep 29, 2006 Patients who received COPAXONE(R) after mitoxantrone showed a trend in experiencing ... "Mitoxantrone carries certain risks which limit its use to a maximum ... Genetic Engineering News - Genetic Engineering News (press release) What's next? Rescue protocols for canine lymphoma.(SMALL ANIMAL) - Aug 1, 2007 Mitoxantrone is considered inferior to doxorubicin for the treatment of canine lymphoma ... Mitoxantrone has the advantage of not having a cumulative limit, ... Free with registration - DVM Newsmagazine - AccessMyLibrary.com Taxotere® (docetaxel) Significantly Improves The Survival Of Patients... - Feb 26, 2007 All statistical comparisons were against mitoxantrone. A primary analysis performed in August 2003 and published in the New England Journal of Medicine in ... Medical News Today - Medical News Today (press release) … Adds to Its Broad Oncology Portfolio With the Approval of Mitoxantr... - Apr 11, 2006 According to IMS, sales in 2005 of mitoxantrone in the United States exceeded $76 million. APP expects to commence marketing mitoxantrone immediately. ... RedOrbit Taxane is new standard for HRPC, but questions remain.(News) - Apr 1, 2006 Quality of life also shows improvement versus mitoxantrone" ... The SWOG 9916 trial compared docetaxel plus estramustine to mitoxantrone plus prednisone. ... $4.95 - Urology Times - ECNext New drug combo fuels hope for MS patients | Article from Deseret News... - Jul 23, 2006 Mitoxantrone is so powerful that it is potentially toxic and can only be used ... Patients were first given a limited course of mitoxantrone, before being ... Pay-Per-View - Deseret News - HighBeam Research Risk factors for invasive aspergillosis in neutropenic patients with ... - Feb 24, 2005 Patients with relapsed AML received two cycles of high dose cytarabin (3000 mg/m 2 given iv over a period of 3 h every 12 h on days 1–4) and mitoxantrone ... Nature.com The outcome of intensive induction therapy in patients 70 years with... - Mar 8, 2007 Those who did not achieve CR with one course were given a second course with mitoxantrone, etoposide and cytarabine as described previously. ... Nature.com QoL improves with 21-day docetaxel regimen: quality of life deteriorat... - Sep 1, 2006 Quality of life deteriorated for fewer patients overall (25.5%) on the mitoxantrone regimen compared with 28.4% of patients on the every-3-weeks docetaxel ... Free with registration - Urology Times - AccessMyLibrary.com Gemtuzumab therapy for isolated extramedullary AML relapse following ... - Feb 27, 2007 Background A 19-year-old male with primary refractory acute myeloid leukemia received salvage therapy with mitoxantrone and cytarabine combination. ... Nature.com Press Release: Pixantrone Shows Activity in a Preclinical Study of … - Feb 11, 2008 The study compared pixantrone with the related drug, mitoxantrone, ... Mitoxantrone has a broad immunosuppressive effect, but has cumulative cardiotoxicity ... Pay-Per-View - PR Newswire - HighBeam Research Press Release: OncoGenex reports lead drug candidate OGX-011 … - Feb 15, 2008 ..."These data show that the combination of OGX-011 with docetaxel or mitoxantrone may improve treatment outcomes in second-line prostate cancer," said Dr. ... Pay-Per-View - PR Newswire - HighBeam Research 使用Mitoxantrone的病患需è¦?é¡?外的心臟檢查 - Jul 30, 2008 July 30, 2008 — 食å“?藥物管ç?†å±€(FDA)ç™¼å‡ºä¸€é …è¦è¨Šï¼Œé€šçŸ¥å?¥åº·ç…§è·å°ˆå®¶å€‘有關於多發性 硬化症（MS）病患接å?—mitoxantrone（以Novaantroneå??稱販售）需è¦?é¡?外接å?—心臟檢查 ... udn.com … Pharmaceutical Partners receives US FDA approval for Mitoxantrone - May 8, 2006 According to IMS, sales in 2005 of mitoxantrone in the United States exceeded $76 million. APP expects to commence marketing mitoxantrone immediately. ... Pay-Per-View - Biotech Week - Factiva, from Dow Jones L'association de la mitoxantrone à la méthylprednisolone améliore la ... - May 12, 2006 Edan G, Miller D, Clanet M, et al. Therapeutic effect of mitoxantrone combined with methylprednisolone in multiple sclerosis: a randomised multicentre study ... EBM Journal (Abonnement) 'Impressive' Complete Remission And 'Survival Data In Relapsed... - Dec 25, 2006 This trial examined the safety and potential efficacy for pixantrone when substituted for mitoxantrone in the FND-R regimen (fludarabine, mitoxantrone, ... Medical News Today - Medical News Today (press release) VENCEN LA ESCLEROSIS MÚLTIPLE CON FÃ?RMACOS PARA EL … - Jul 22, 2006 La mitoxantrone es una droga para combatir el cáncer tan potente que puede resultar tóxica. Se usa solo por perÃodos cortos. Por ello, Boggild y sus colegas ... $2.95 - El Nuevo Herald - NewsBank Taxane-refractory PCa: Regimens offer modest results: research paves ... - Sep 1, 2006 The options are few for these patients, and mitoxantrone/prednisone has become the ... "Mitoxantrone looks more active than we expected," Dr. Rosenberg told ... $4.95 - Urology Times - ECNext Phase II study of oral capecitabine in patients with hormone-refractor... - Mar 23, 2005 Chemotherapy with mitoxantrone plus prednisone or prednisone alone for symptomatic ... Hydrocortisone with or without mitoxantrone in men with ... Nature.com Article: Drug Combination Fuels Hope for MS Fight - AP Online | … - Jul 21, 2006 Mitoxantrone is an anti-cancer drug so powerful that it is potentially toxic ... Patients were first given a limited course of mitoxantrone, before being ... Pay-Per-View - Associated Press/AP Online - HighBeam Research Drug Combination Fuels Hope for MS Fight | Article from AP Online | … - Jul 21, 2006 Mitoxantrone is an anti-cancer drug so powerful that it is potentially toxic ... Patients were first given a limited course of mitoxantrone, before being ... Pay-Per-View - Associated Press/AP Online - HighBeam Research Radioimmunotherapy After Chemo Safe for Common Lymphoma - Mar 12, 2008 It found that radioimmunotherapy with the radioactive drug yttrium-90 (90Y) ibritumombab tiuxetan, following chemotherapy with fludarabine and mitoxantrone ... ABC News 'Impressive' Complete Remission and 'Durable' Survival Data in... - Dec 10, 2006 This trial examined the safety and potential efficacy for pixantrone when substituted for mitoxantrone in the FND-R regimen (fludarabine, mitoxantrone, ... Genetic Engineering News - Genetic Engineering News (press release) Diagnosis, treatment of transitional cell carcinoma (TCC) in dogs - Jul 1, 2008 The addition of adjuvant therapies such as piroxicam and/or mitoxantrone may ... As a single agent, mitoxantrone has been shown to have limited activity, ... DVM 360 טר×? תחילת הטיפול בקופקסון משיג תוצ×?ות טובות בהרבה מ×?שר טיפול ? - Sep 29, 2006 ...הטוען ×›×™ חולי×? במחלת הטרשת ×”× ×¤×•×¦×” ×?שר טופלו תחילה בתרופת ×”- Mitoxantrone ורק ל×?חר מכן עברו ... Bizportal The Use of Imaging in the Early Development of Neuropharmacological … - Jun 28, 2007 Imaging to support the clinical efficacy of mitoxantrone. Mitoxantrone is indicated for reducing neurologic disability and/or the frequency of clinical ... Nature.com Il Pixandrone riduce gravità malattia MG, Cell T. vola - Feb 11, 2008 Lo studio ha comparato l'efficacia del Pixantrone con il Mitoxantrone, un farmaco di uso corrente nel trattamento della sclerosi multipla grave, ... Milano Finanza Stage 4 neuroblastoma: sequential hemi-body irradiation or high-dose ... - May 17, 2005 Our aim was to explore the role of high-dose sequential cyclophosphamide, etoposide and mitoxantrone+melphalan in erasing residual neoplastic clones proving ... Nature.com Prostate cancer drug cleared for free use - Jun 28, 2006 Another anti-cancer drug, mitoxantrone, is sometimes given to this group of ... In practice both Taxotere and mitoxantrone are given in conjunction with a ... Daily Mail ixabepilone Bristol-Myers Squibb clinical data (phase II) (prostate... - Jun 13, 2005 Data from a randomized phase II trial of ixabepilone or mitoxantrone and ... mitoxantrone and prednisone patients and six third line mitoxantrone and ... Pay-Per-View - R & D Focus Drug News - Factiva, from Dow Jones Aplidin synergizes with cytosine arabinoside: functional relevance of... - Aug 23, 2007 Aplidin was combined with methotrexate, doxorubicin, mitoxantrone, methylprednisolone, vinblastine and cytarabine at a fixed ratio of doses that ... Nature.com Long-term follow-up of patients with peripheral T-cell lymphomas... - Jul 27, 2006 Conditioning regimen consisted of mitoxantrone (60 mg/m 2 ) and melphalan (180 mg/m 2 ) or carmustine, etoposide, Ara-C and melphalan followed by peripheral ... Nature.com Graft clonogenicity and intensity of pre-treatment: factors affecting... - May 31, 2005 Every patient received two induction courses (IC) consisting of MAV (mitoxantrone 10 mg/m 2 once daily intravenously (iv) days 4–8, total dose 50 mg/m 2 ... Nature.com Intensive consolidation versus oral maintenance therapy in patients... - Jan 26, 2006 Postremission therapy in older patients with de novo acute myeloid leukemia: a randomized trial comparing mitoxantrone and intermediate-dose cytarabine with ... Nature.com Phase III trials in oncology: setting standards of care? - Feb 17, 2005 8 examined docetaxel plus prednisone and mitoxantrone plus prednisone in such patients. ... Hence, the issue is not whether a mitoxantrone or a taxane-based ... Nature.com Imatinib mesylate for refractory acute myeloblastic leukemia harboring... - Jul 28, 2005 HDAC combined with mitoxantrone and vindesine had no response. On the basis of Western blot analysis (Figure 1b), he received imatinib at a dosage 400 ... Nature.com A role for topoisomerase II in the formation of radiation-induced... - Jul 29, 2008 Promyelocytic leukaemic parental HL60 and mitoxantrone-resistant variants ... Harker WG, Slade DL, Drake FH, Parr RL (1991) Mitoxantrone Resistance in HL-60 ... Nature.com Brand Names/Synonyms: Mitoxantrone is also known by the following brand names and/or synonymsCCRIS 7604; CHEMBANK1135; DHAD; DHAQ; Dhaq Hcl; Dihydroxyanthraquinone; Immunex; M6545; Mitox; Mitoxanthrone; Mitoxantron; Mitoxantrona [Inn-Spanish]; Mitoxantrone; Mitoxantrone 2hcl; Mitoxantrone Dihydrochloride; Mitoxantrone Hcl; Mitoxantrone Hydrochloride; Mitoxantronum [Inn-Latin]; Mitozantrone; Mitozantrone Hydrochloride; Novantron; Novantrone Drug Category: Mitoxantrone is categorized under the following by the FDA: Antineoplastic Agents; Analgesics; ATC:L01DB07 Dosage Forms: Solution Absorption: poor (oral) Interactions: [an error occurred while processing this directive] Chemical IUPAC Name: 1,4-dihydroxy-5,8-bis[2-(2-hydroxyethylamino)ethylamino]-anthracene-9,10-dione |
|
Health Home | Conditions | Cancer | Medications | Surgery | Vaccines The Cancer News Network
COPYRIGHT 2009 CANCERNEWSNETWORK | Privacy |