Montelukast

This page contains recent news articles, when available, and an overview of Montelukast but does not offer medical advice. You should contact your physician with regard to any health issues or concerns.


Overview:

Montelukast
(when available)

Pharmacology and use:
Montelukast, like zafirlukast, is a leukotriene receptor antagonist used as an alternative to anti-inflammatory medications in the management and chronic treatment of asthma and exercise-induced bronchospasm (EIB). Unlike zafirlukast, montelukast does not inhibit CYP2C9 or CYP3A4 and is, therefore, not expected to affect the hepatic clearance of drugs metabolized by these enzymes. For the treatment of asthma

Mechanism Of Action:
Montelukast selectively antagonizes leukotriene D4 (LTD4) at the cysteinyl leukotriene receptor, CysLT1, in the human airway. Montelukast inhibits the actions of LTD4 at the CysLT1 receptor, preventing airway edema, smooth muscle contraction, and enhanced secretion of thick, viscous mucus.

News Articles on Montelukast

Montelukast cannot replace prednisolone in children with stabilized acute asthma  -  ‎Dec 10, 2009‎
NEW YORK (Reuters Health) - Montelukast is not an adequate alternative to oral corticosteroids for children with mild-to-moderate acute asthma after ... news Stories

Best Evidence Review: Long-acting Beta-Agonists -- Are They Appropriate for ...  -  ‎Dec 30, 2009‎
Linear growth in prepubertal asthmatic children treated with montelukast, beclomethasone, or placebo: a 56-week randomized double-blind study. ... Medscape

Pharmaceutical industry financial performance  -  ‎Dec 11, 2009‎
Several major branded products — for example, atorvastatin (Lipitor; Pfizer), venlafaxine (Effexor; Wyeth), olanzapine (Zyprexa; Lilly), montelukast ... Nature.com (subscription)

Инхалаторните кортикоÑ?тероиди Ñ?а по-ефективни от montelukast при деца Ñ? аÑ?тма ...  -  ‎Dec 11, 2009‎
Инхалаторните кортикоÑ?тероидите може би Ñ?а по-ефективни от montelukast при деца и юноши Ñ? аÑ?тма, Ñ?очат резултатите на широк мета-анализ, публикуван в ... DoctorBG.com

En Pastillas  -  ‎Dec 14, 2009‎
...cumple su producto Singular (Montelukast, MSD), tratamiento para el control del asma y la rinitis alérgica, desde su lanzamiento al mercado venezolano. ... El Universal (Venezuela)

SÄ… wreszcie rozporzÄ…dzenia refundacyjne  -  ‎Dec 10, 2009‎
Spowodowane to będzie obniżkami limitów, w szczególności dotyczących produktów z grupy substancji montelukast, olanzapina i fentanyl. ... Medycyna Praktyczna

ACAAI: Tots with Asthma Benefit from Montelukast  -  ‎Nov 12, 2009‎
Explain to interested patietns that this study suggests that montelukast therapy is effective in children ... MedPage Today

Fluticasone Plus Salmeterol Associated With Fewer Asthma Exacerbations ...  -  ‎Nov 13, 2009‎
...on a fixed-dose combination, experienced fewer serious asthma exacerbations when compared with the use of inhaled corticosteroids plus montelukast, ... DG News

Merck Announces Third-Quarter 2009 Financial Results  -  ‎Oct 22, 2009‎
Product Performance Highlights Worldwide sales of SINGULAIR (montelukast sodium), a once-a-day oral medicine indicated for the chronic treatment of asthma ... Reuters

Inhaled Steroids Still Most Effective Treatment for Asthma  -  ‎Oct 22, 2009‎
Nonsteroidal controller medications such as Singulair (montelukast) are the latest drug treatment option to become available. There is not yet enough data ... UK News

POpuliÅ›ci, nieroby i partacze  -  ‎Nov 12, 2009‎
...opieszałość ekipy Tuska, budżet NFZ-u traci duuże pieniądze (podpowiem, że chodzi np. o limity na montelukast). Podobno nowe listy mają wejść 1 grudnia. ... Salon 24

Orkan in den Atemwegen  -  ‎Oct 27, 2009‎
Es ist auch eine antientzündliche Therapie mit Leukotrienantagonisten (Zafirlukast, Montelukast) möglich. In der überwiegenden Anzahl der Fälle sistiert ... Pharmazeutische Zeitung online

Mild Asthmatics May Do Well With Less Medicine  -  May 16, 2007
About 30 percent of the montelukast group experienced a treatment failure. For the purposes of this study, Peters and his colleagues very broadly defined ... Washington Post

Singulair not linked to suicide, depression  -  Sep 4, 2008
In fact, there was an indication that montelukast therapy actually had a beneficial effect in this regard. "While our review of ACRC trial data is ... Reuters India

Telithromycin, but not montelukast, increases the plasma concentration...  -  Aug 4, 2005
Lauri I. Kajosaari MB 1 , Mikko Niemi MD 1 , Janne T. Backman MD 1 and Pertti J. Neuvonen MD 1. Correspondence: Janne T. Backman, MD, Department of Clinical ... Nature.com

Short-Course Montelukast Improves Outcomes for Intermittent Asthma...  -  Feb 16, 2007
February 16, 2007 — In children with intermittent asthma, a short course of montelukast resulted in reduction in acute healthcare resources, asthma symptoms ... Medscape

Sudafed As Effective Treating Hay Fever As Prescription Drug  -  Feb 21, 2006
...“Our hypothesis was that montelukast would have additional benefits and pseudoephedrine would interfere with sleep, but when we compared them head-to-head ... FOXNews

… US Label Change for SINGULAIR(R) (Montelukast Sodium): New Growth …  -  Dec 13, 2005
The structural formula is: (Graphic Omitted) Montelukast sodium is a ... Montelukast sodium is freely soluble in ethanol, methanol, and water and ... RedOrbit

Schering-Plough and Merck say FDA accepts allergy drug for review  -  Aug 28, 2007
The companies said they are seeking approval for loratadine/montelukast as treatment of allergic rhinitis symptoms in patients who want relief from nasal ... Forbes

No Added Benefit When Montelukast Added to Fluticasone/Salmeterol in ...  -  May 23, 2008
By Marvin Ross. TORONTO -- May 23, 2008 -- Patients with both asthma and allergic rhinitis experience significantly better lung function when they are ... DG News

Dealing with both asthma and allergic rhinitis  -  Sep 22, 2007
Montelukast belongs to a class of medications called leukotriene modifiers ... Montelukast is used to prevent asthma attacks (not used to relieve an attack ... Inquirer.net

Montelukast (Systemic).(Drug overview)  -  May 1, 2006
Montelukast (mon-te-LOO-kast) is used in mild to moderate asthma to decrease the symptoms of asthma and the number of acute asthma attacks. ... Free with registration - USP DI-Volume II, Advice for the... - AccessMyLibrary.com

Montelukast significantly reduced Asthma exacerbations in young …  -  Feb 16, 2005
By Nikhil, Journals Correspondent, [RxPG] Montelukast, a leukotriene receptor antagonist, significantly decreased the rate of exacerbations and lengthened ... RxPG NEWS

… NBA/Jr. WNBA Skills Challenge sponsored by SINGULAIR® (montelukast …  -  Dec 1, 2008
The Jr. NBA/Jr. WNBA Skills Challenge, sponsored by SINGULAIR, is a FREE program that is easy to administer. Boys and girls ages 9 - 14* compete separately ... NBA.com

Don't sniff at cheaper allergy drugs  -  Feb 21, 2006
Montelukast, originally designed to treat asthma, reduces leukotrienes, substances released during the allergic response that cause inflammation. ... Globe and Mail

… -Plough/Merck Pharmaceuticals Submit NDA for Loratadine/Montelukast  -  Aug 29, 2007
Schering-Plough/Merck Pharmaceuticals said they are seeking US marketing approval of loratadine/montelukast for treatment of allergic rhinitis symptoms. ... FDA news - FDA news (subscription)

Montelukast (Systemic).  -  Oct 27, 2005
Montelukast (mon-te-LOO-kast) is used in mild to moderate asthma to decrease the symptoms of asthma and the number of acute asthma attacks. ... Free with registration - USP DI-Volume II, Advice for the... - AccessMyLibrary.com

Fluticasone vs. Montelukast for Mild Persistent Asthma  -  Mar 1, 2006
Inhaled corticosteroids are first-line medications for daily control of persistent asthma. Leukotriene receptor antagonists have shown a comparable ... AAFP News Now

Codexis, Arch Pharmalabs in strategic collaboration Silicon Valley /...  -  Aug 25, 2008
Other planned future products include generic intermediates and APIs for montelukast (asthma/allergy) and esomeprazole (ulcers), as well as a key ... Bizjournals.com

Learn about Montelukast from Consumer Reports Health.  -  Jan 5, 2007
Pending revision, the material in this section should be considered in light of more recently available information in the MedWatch notification at the ... consumerreports.org

Safety, Tolerability, and Exploratory Efficacy of Montelukast in 6-...  -  Jul 13, 2005
Objective: The purpose of this study was to determine the safety and tolerability profile of montelukast 4-mg oral granules compared with placebo in ... RedOrbit

Montelukast ineffective for bronchiolitis in hospitalized infants  -  Dec 26, 2008
...by Will Boggs, MD. NEW YORK (Reuters Health) - The cysteinyl leukotriene receptor antagonist montelukast is of no benefit in treating acute bronchiolitis in ... news Stories

The Effect of Montelukast on Exhaled Nitric Oxide and Lung Function...  -  Feb 23, 2005
Objective: The study was undertaken to investigate the influence of once-daily treatment with montelukast (Singulair; MSD; Glattbrugg, Switzerland) on ... RedOrbit

Over-the-counter decongestant equals prescription drug in relieving...  -  Feb 20, 2006
..."Our hypothesis was that montelukast would have additional benefits and ... On the other hand, Montelukast, originally designed to treat asthma, ... eurekalert.org

Montelukast Helps Reduce Risk for Worsened Asthma Symptoms in …  -  Sep 14, 2007
September 14, 2007 — During the annual September asthma epidemic, adding montelukast to usual treatment in children reduces the risk for worsened asthma ... Medscape

Study downgrades montelukast link with syndrome  -  Feb 15, 2008
Onset of Churg-Strauss syndrome (CSS), a rare but potentially life-threatening condition, is probably not specifically associated with the drug montelukast ... Pharmacy Europe

Montelukast (Singulair) Added to Antihistamine or Corticosteroid...  -  Nov 11, 2005
By Crystal Phend. ANAHEIM, CA -- November 11, 2005 -- Antihistamines appear to have similar efficacy to corticosteroid nasal sprays for poorly controlled ... DG News

Asthma; Montelukast treated children age 2-5 demonstrate less health ...  -  Sep 26, 2006
2006 SEP 26 - (NewsRx.com) -- Children 2-5 years old demonstrate less asthma-related health care resource use while on montelukast. ... Pay-Per-View - Life Science Weekly - Factiva, from Dow Jones

Modest relief with montelukast for kids' asthma attacks.(POEMs[R]:...  -  May 1, 2007
Robertson CF, Price D, Henry R, et al. Short-course montelukast for intermittent asthma in children: a randomized controlled trial. ... Free with registration - Journal of Family Practice - AccessMyLibrary.com

FDA Investigates Possible Suicide Link With Montelukast (Singulair)  -  Mar 27, 2008
By Peggy Peck, Executive Editor, MedPage Today. ROCKVILLE, Md., March 27 -- The FDA said it will probably take at least nine months for it to complete a ... MedPage Today

Montelukast Therapy in Children with Asthma  -  Nov 1, 2005
Results of studies assessing the effectiveness of anti-inflammatory agents for young children with asthma have been inconsistent. ... AAFP News Now

Over-the-counter Decongestant Equals Popular Prescription Drug in …  -  Mar 16, 2006
..."Our hypothesis was that montelukast would have additional benefits and ... On the other hand, Montelukast, originally designed to treat asthma, ... emaxhealth.com

Montelukast protects against exercise-induced bronchoconstriction  -  Oct 9, 2007
NEW YORK (Reuters Health) - A single dose of montelukast provides significant protection against exercise-induced bronchoconstriction, according to results ... news Stories

Obesity Affects Response to Asthma Treatments: Presented at ACAAI  -  Nov 10, 2008
The analysis pooled data from 2 previously published, double-blind, randomised, parallel-group, 12-week trials that compared fluticasone and montelukast in ... DG News

Montelukast, fluticasone propionate similarly cut ED visits for...  -  Jan 1, 2005
ORLANDO, FLA. -- Medicaid patients with asthma responded similarly to monotherapy with either montelukast or fluticasone propionate in a study presented as ... Free with registration - Family Practice News - AccessMyLibrary.com

Montelukast role in childhood asthma  -  Dec 1, 2006
By Gabrielle Babbington. A SHORT course of montelukast (Singulair) in children with virally triggered asthma can improve symptoms and reduce school absences ... Pay-Per-View - Australian Doctor - Factiva, from Dow Jones

Fluticasone and Montelukast in Mild-to-Moderate Childhood Asthma  -  Feb 14, 2006
This study of 144 children was conducted by the Childhood Asthma Research and Education (CARE) Network of the National Heart, Lung, and Blood Institute, ... Medscape

New Indication for SINGULAIR(R) (montelukast sodium) Approved to …  -  Apr 25, 2007
EIB is typically characterized by shortness of breath, cough, wheeze and chest tightness brought on by exercise. "EIB affects a broad spectrum of the asthma ... Free with registration - Business Wire - AccessMyLibrary.com

Leukotriene Receptor Antagonists for the Treatment of Allergic Skin …  -  Jul 1, 2008
In four trials enrolling adults, the effectiveness of montelukast was measured using ... One case series and one small RCT suggested that montelukast was ... AAFP News Now

No Additional Benefit From Adding Montelukast to Fluticasone Propionat...  -  Nov 10, 2005
By Crystal Phend. ANAHEIM, CA -- November 10, 2005 -- Adding montelukast (Singulair) to fluticasone propionate may not improve airway inflammation in ... DG News

… -daily fluticasone plus salmeterol superior to montelukast as step...  -  Aug 1, 2007
Patients receiving either of these therapies had statistically significant lower rates of treatment failure compared with patients receiving montelukast ... Free with registration - Formulary - AccessMyLibrary.com

Inhaled Steroid Use and Asthma Control in Patients with Mild Persisten...  -  Jul 1, 2008
In this case, the authors use the montelukast failure rate of 30 percent as a baseline, and consider the 20 percent failure rate with once-daily ... AAFP News Now

Effects of Asthma Medications May Vary Between Obese, Lean People; …  -  Feb 22, 2006
Singulair is the brand name of montelukast sodium and is sold by Merck & Co., ... The data included the patients' responses to Singulair/montelukast, ... Free with registration - Europe Intelligence Wire - AccessMyLibrary.com

Pfizer Global Research & Development; Montelukast is a selective …  -  Apr 27, 2005
2005 APR 27 - (NewsRx.com) -- In addition to its other effects, montelukast acts as a selective CYP2C8 inhibitor. In a study from the United States, ... Pay-Per-View - Biotech Week - Factiva, from Dow Jones

Temporary Addition of Montelukast to Usual Therapy Reduces Risk of …  -  Feb 26, 2007
By Bryan DeBusk. SAN DIEGO, CA -- February 26, 2007 -- By supplementing existing control measures with a readily available leukotriene receptor antagonist, ... DG News

The effect of montelukast on exhaled nitric oxide and lung function...  -  Feb 1, 2005
Objective: The study was undertaken to investigate the influence of once-daily treatment with montelukast (Singulair; MSD; Glattbrugg, Switzerland) on ... Pay-Per-View - Chest - Factiva, from Dow Jones

ICS Most Effective for Persistent Asthma in Children  -  Jan 17, 2006
Response Profiles to Fluticasone and Montelukast in Mild-to-Moderate Persistent ... Researchers found both fluticasone and montelukast led to significant ... newswise.com

… Announce Withdrawal of Loratadine/Montelukast NDA and Termination ...  -  Jun 27, 2008
Schering-Plough and Merck Announce Withdrawal of Loratadine/Montelukast NDA and Termination of Respiratory Joint Venture. from PR Newswire. Pay-Per-View - PR Newswire - HighBeam Research

Drug Reduces Unscheduled Trips To Doctor for Childhood Asthma …  -  Feb 8, 2007
By the end of the year-long study, the patients treated with montelukast had 163 ... Montelukast sodium, a specific leukotriene receptor antagonist that has ... newswise.com

Intermittent asthma flares reduced in children taking montelukast.(Cli...  -  Sep 1, 2005
A daily dose of the leukotriene-receptor antagonist montelukast resulted in ... Patients were randomized to receive one daily montelukast tablet (4 mg or 5 ... Pay-Per-View - Family Practice News - Factiva, from Dow Jones

Treatments and drugs  -  Nov 14, 2008
Churg-Strauss syndrome in patients receiving montelukast as treatment for asthma. Chest. ... The leukotriene receptor antagonist montelukast and the risk of ... MayoClinic.com

JournalWatch: Montelukast doubts.(Brief article)  -  Mar 1, 2007
Their randomised, placebo-controlled crossover trial compared treatment with montelukast plus salmeterol and beclomethasone plus salmeterol in 192 patients ... Free with registration - Pulse - AccessMyLibrary.com

… flares reduced in children taking montelukast.(Clinical Rounds) |...  -  Sep 1, 2005
Intermittent asthma flares reduced in children taking montelukast. ... A daily dose of the leukotriene-receptor antagonist montelukast resulted in fewer ... Pay-Per-View - Family Practice News - HighBeam Research

Montelukast acts rapidly to prevent bronchospasm.(Pulmonary Medicine)...  -  Jun 15, 2005
Montelukast acts rapidly to prevent bronchospasm.(Pulmonary Medicine) ... find Internal Medicine News articles. SAN ANTONIO -- Montelukast can protect ... Pay-Per-View - Internal Medicine News - HighBeam Research

New Indication for SINGULAIR® (montelukast sodium) Approved to …  -  Apr 30, 2007
WHITEHOUSE STATION, NJ,- Merck & Co., Inc. announced today that the US Food and Drug Administration (FDA) has approved a new indication for SINGULAIR® ... webwire.com

Some Kids Benefit More From Asthma Drug  -  May 14, 2008
Montelukast, one of the most widely prescribed medications for asthma and ... However, physicians have found that montelukast is quite variable in its ... sciencedaily.com

Asthma; Montelukast significantly reduces asthma exacerbations in...  -  Mar 8, 2005
2005 MAR 8 - (NewsRx.com & NewsRx.net) -- Montelukast, a leukotriene receptor antagonist, significantly decreased the rate of exacerbations and lengthened ... Pay-Per-View - Life Science Weekly - Factiva, from Dow Jones

Research guides medication choices for young Asthma patients  -  Jan 28, 2005
Patients who responded to montelukast were generally younger and had asthma ... Response to fluticasone but not montelukast was associated with more use and ... PsychCentral.com

Asthma; Montelukast significantly reduces asthma exacerbations in...  -  Mar 11, 2005
2005 MAR 11 - (NewsRx.com & NewsRx.net) -- Montelukast, a leukotriene receptor antagonist, significantly decreased the rate of exacerbations and lengthened ... Pay-Per-View - Drug Week - Factiva, from Dow Jones

American Lung Association Study Finds No Evidence Of Depression Or …  -  Sep 2, 2008
There has been recent concern that suicide may be a complication of montelukast (Singulair) therapy. Montelukast is a Food and Drug Administration (FDA) ... Medical News Today - Medical News Today (press release)

US FDA accepts for filing NDA for fixed-dose loratadine/montelukast …  -  Sep 3, 2007
US FDA accepts for filing NDA for fixed-dose loratadine/montelukast combo pill. Schering-Plough and Merck Pharmaceuticals, a unit of fellow US drug major ... $9.94 - Pharma Marketletter - Alacra Store

Montelukast.  -  Jul 1, 2007
Montelukast. Camargo CA, Smithline HA, Malice MP, Green SA, Reiss TEA randomized controlled trial of intravenous montelukast in acute asthma. ... $9.94 - Formulary - Alacra Store

Montelukast.(Selected literature)(Brief article)  -  Jul 1, 2007
...* Montelukast. Camargo CA, Smithline HA, Malice MP, Green SA, Reiss TEA randomized controlled trial of intravenous montelukast in acute asthma. $4.95 - Formulary - ECNext

Article: Montelukast cuts intermittent asthma exacerbations.(Clinical...  -  May 1, 2005
Montelukast cuts intermittent asthma exacerbations.(Clinical Rounds)(Brief Article) ... find Pediatric News articles. Pay-Per-View - Pediatric News - HighBeam Research

Montelukast (Singulair, Merck) was approved to treat the symptoms of ...  -  Sep 1, 2005
...* Montelukast (Singulair, Merck) was approved to treat the symptoms of perennial allergic rhinitis in adults and children aged 6 months or older. $4.95 - Formulary - ECNext

New Data Reinforces Use of Singulair(tm) in Asthma Patients with...  -  Jul 10, 2005
Singulair(tm) (montelukast) significantly improved symptoms of both allergic ... "These results clearly confirm that montelukast can play an important role ... i-newswire.com

Ghana Football Association ::: Print News  -  Feb 24, 2007
Conclusions response to montelukast and the physician or any given patient. You have worsening of montelukast during human daily oral dose for 2 months. ... Ghana Football Association

International Approvals: Singulair and Gardasil/Silgard  -  Oct 2, 2006
On September 19, Health Canada approved a new indication for montelukast sodium ... Approval of the allergic rhinitis indication for montelukast sodium was ... Medscape

Pharmacotherapy — first-line maintenance therapy  -  Sep 13, 2005
Montelukast or placebo was administered in addition to ICSs in 28% of ... Overall, when used either as an add-on or monotherapy, montelukast was found to be ... CMAJ

American Lung Association Study Finds No Evidence of Depression or …  -  Aug 31, 2008
American Lung Association Study Finds No Evidence of Depression or Suicide Linked to Asthma and Allergy Drug Montelukast. ... find Ascribe Higher Education ... Pay-Per-View - Ascribe Higher Education News Service - HighBeam Research

Step-down therapy feasible for stabilized asthma.(Pulmonary Medicine)(...  -  Jul 15, 2006
Even so, the patients on montelukast fared well enough that all three regimens ... There were 50 treatment failures with montelukast, 34 with fluticasone, ... Free with registration - Family Practice News - AccessMyLibrary.com

Reports of suicidality in patients using Singulair to be investigated....  -  Apr 15, 2008
GlaxoSmithKline) twice daily and 170 others to 5 mg montelukast (Singulair, Merck) once daily. Participants in the randomized, double ... with montelukast. ... Pay-Per-View - Family Practice News - HighBeam Research

FDA Approvals: ProQuad, Ambien CR, Singulair  -  Sep 8, 2005
On July 27, the FDA approved a new indication for montelukast sodium (Singulair, ... Montelukast sodium is available in tablet form for adults (10 mg), ... Medscape

Step-down therapy feasible for stabilized asthma.(Pulmonary Medicine)  -  Sep 15, 2006
Even so, the patients on montelukast fared well enough that all three regimens ... There were 50 treatment failures with montelukast, 34 with fluticasone, ... $4.95 - Internal Medicine News - ECNext

Article: FDA investigating suicide risks of some drugs - Deseret News...  -  Sep 1, 2008
FDA) has approved a new indication for SINGULAIR([R]) (montelukast sodium) to prevent ... in patients aged 15 years and older. SINGULAIR is the first and ... Pay-Per-View - Deseret News - HighBeam Research

Indications for Merck's SINGULAIR(R) Expand with FDA Approval for …  -  Aug 18, 2005
The structural formula is: (GRAPHIC OMITTED) Montelukast sodium is a ... Montelukast sodium is freely soluble in ethanol, methanol, and water and ... $4.95 - Business Wire - ECNext

New Study Demonstrates Adding 'Singulair' To Children's Usual Asthma ...  -  Oct 5, 2007
The montelukast group were also four times less likely than those receiving placebo to ... In this study, the addition of an oral therapy, montelukast, ... Medical News Today - Medical News Today (press release)

Singulair helpful for kids with asthma and allergies  -  Sep 7, 2005
Rather than a steroid, montelukast is technically a leukotriene receptor ... The study suggests that "montelukast is a cost-effective alternative to inhaled ... RedOrbit

FDA Approvals: Fluocinolone Ear Drops, Fosrenol, Singulair  -  Dec 15, 2005
Growth rates (expressed as LS mean in cm/year) for the montelukast sodium, ... Montelukast sodium is indicated for the prophylaxis and chronic treatment of ... Medscape

Can a leukotriene modifier manage both asthma and allergic rhinitis?(...  -  Feb 1, 2005
Protective effect of montelukast on lower and upper respiratory tract ... They found that montelukast had a protective effect against both upper and lower ... $4.95 - Journal of Respiratory Diseases - ECNext

æœ?氣喘藥欣æµ?想自殺? 醫師:國內未è?½é?Žä¸?良å??應通報  -  Mar 28, 2008
...美國FDA日�發布治療氣喘的藥物「欣��(Montelukast)�能導致病患行為改變,甚至 ... 目�國內衛生署核准�Montelukast�分藥�許�證共8張,核准的�應症為「�用於 ... NOWnews

Over-the-counter decongestant as good as prescription drug in...  -  Feb 24, 2006
24 Hour) were just as effective as 10 mg daily of montelukast sodium (Singulair. ... "Our hypothesis was that montelukast would have additional benefits and ... News-Medical.net

… -PLOUGH/MERCK: STOPP SAMARBETE LORATADINE/MONTELUKAST  -  Jun 27, 2008
STOCKHOLM (Direkt) Läkemedelsbolagen Schering-Plough och Merck avslutar samarbetet när det gäller läkemedlen loratidine och montelukast. ... Dagens Nyheter

Once-daily corticosteroids for mild, persistent asthma.(Tips from...  -  Jan 15, 2008
The montelukast group had a significantly greater treatment failure rate (30.3 ... Nocturnal asthma symptoms were more commonly reported in the montelukast ... Free with registration - American Family Physician - AccessMyLibrary.com

Leukotriene inhibitors in the treatment of allergy and asthma.  -  Jan 1, 2007
Montelukast is administered orally once daily and is approved for treatment ... Montelukast is classified by the U.S. Food and Drug Administration (FDA) as ... Free with registration - American Family Physician - AccessMyLibrary.com

Article: Pricey drug no better than cheap allergy medication, study...  -  Feb 20, 2006
FDA) has approved a new indication for SINGULAIR([R]) (montelukast sodium) to prevent ... in patients aged 15 years and older. SINGULAIR is the first and ... Pay-Per-View - South Florida Sun - Sentinel - HighBeam Research

Two asthma drugs' efficacy compared.(Pulmonary Medicine)  -  Oct 15, 2005
Fluticasone was significantly more cost effective than was montelukast and earned higher satisfaction ratings among parents and physicians, reported Nancy ... Free with registration - Family Practice News - AccessMyLibrary.com

OTC Decongestant Equals Prescription Drug for Hay Fever  -  Feb 16, 2006
..."Our hypothesis was that montelukast would have additional benefits and ... On the other hand, Montelukast, originally designed to treat asthma, ... newswise.com

Drug Reduces Unscheduled Trips To Doctor For Childhood Asthma …  -  Feb 12, 2007
By the end of the year-long study, the patients treated with montelukast had 163 ... Montelukast sodium, a specific leukotriene receptor antagonist that has ... Medical News Today - Medical News Today (press release)

Reducing Treatment in Mild Persistent Asthma  -  Jul 3, 2007
Matching placebo controls for montelukast tablets and the inhaled medications ... They note that montelukast is not as effective, but provides good asthma ... Medscape

… -Rezeptor-Antagonisten - therapeutischer Nutzen von Montelukast …  -  May 17, 2006
Geprüft wurden die Indikationen und Therapieansätze, für die Montelukast zum ... Aussagen zu langfristigen Nebenwirkungen von Montelukast sind derzeit ... uni-protokolle.de

Krka in Salus tožena zaradi domnevne krÅ¡itve patenta  -  Dec 5, 2008
Frosst Canada Limited iz Kanade proti toženima strankama, družbi Salus in družbi Krka, zaradi domnevne krÅ¡itve patenta, ki Å¡Ä?iti uÄ?inkovino montelukast. ... STA

Nueva indicación para montelukast aprobada en la UE  -  Apr 20, 2005
El montelukast (Singulair), tradicionalmente utilizado para el tratamiento y control del asma, acaba de recibir la aprobación por parte de las autoridades ... doyma.es

Montelukast bei bronchialer und nasaler allergischer Inflammation  -  Mar 21, 2005
Asthma bronchiale und allergische Rhinitis sind weit verbreitete Atemwegserkrankungen. In Deutschland leiden bis zu 5 Millionen Menschen unter Asthma, ... journalmed.de

Leukotrienes: their role in the treatment of asthma and seasonal...  -  Jan 1, 2005
Montelukast is recommended as an alternative medication to inhaled ... In January 2003, the FDA approved montelukast for use as monotherapy in the treatment ... $4.95 - Pediatric Nursing - ECNext

Kindliches Asthma: Wirksamkeit und gute Compliance mit Montelukast …  -  Sep 19, 2008
Bei Kindern mit leichtem intermittierenden oder persistierenden Asthma erwies sich der Leukotrien-Antagonist Montelukast als wirksame Controller-Therapie, ... journalmed.de

Monkasta nemoteno v prodaji  -  Mar 13, 2008
...izdelka v Sloveniji, ki kot zdravilno uÄ?inkovino vsebuje montelukast, in sicer zaradi domnevne krÅ¡itve patenta družbe Merck, ki Å¡Ä?iti ta proizvod. ... 24ur.com

Virusbedingte Asthmaanfälle mit Montelukast oft vermeidbar  -  Sep 28, 2006
MÜNCHEN (sto). Ein häufiger Auslöser vom Asthma-Exazerbationen bei Kindern sind Virusinfektionen. Mit dem Leukotrienrezeptor-Antagonisten Montelukast lassen ... Ärzte Zeitung

… più efficace e conveniente rispetto a montelukast nell'asma...  -  Aug 23, 2008
I bambini asmatici trattati con montelukast hanno avuto una maggior probabilità di fallimento terapeutico rispetto a quelli trattati con fluticasone spray ... Pillole.org

Leukotriene inhibitors in the treatment of allergy and asthma.  -  Jan 1, 2007
Montelukast is administered orally once daily and is approved for treatment ... Montelukast is classified by the U.S. Food and Drug Administration (FDA) as ... $4.95 - American Family Physician - ECNext

Asthma – Entzündung der besonderen Art  -  Nov 30, 2007
Der Leukotrien-Antagonist Montelukast hemmt die Entzündung über einen ... Außer bei Asthma setzt Dr. Hausen Montelukast auch zur Behandlung von Heuschnupfen ... Medical Tribune Magazin - Medical Tribune Magazin

Czy montelukast jest skuteczny w zaostrzeniach astmy u dzieci?  -  May 31, 2007
Według aktualnych zaleceń, lekami pierwszego wyboru w leczeniu zaostrzenia astmy są wziewne szybko działające beta 2 -mimetyki oraz podaż tlenu. ... Medycyna Praktyczna

Brand Names/Synonyms:
Montelukast is also known by the following brand names and/or synonymsMontelukast; Singulair; Singular

Drug Category:
Montelukast is categorized under the following by the FDA: Antiarrhythmic Agents; Unclassified Therapeutic Agents (92:00.00); ATC:R03DC03

Dosage Forms:
Oral tablets

Absorption:
rapidly absorbed following oral administration (bioavailability is 64%)

Interactions:
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Chemical IUPAC Name:
2-[1-[[1-[3-[2-(7-chloroquinolin-2-yl)ethenyl]phenyl]-3-[2-(1-hydroxy-1-methyl-ethyl)phenyl]-propyl]sulfanylmethyl]cyclopropyl]ethanoicacid





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