Nelfinavir

This page contains recent news articles, when available, and an overview of Nelfinavir but does not offer medical advice. You should contact your physician with regard to any health issues or concerns.


Overview:

Nelfinavir
(when available)

Pharmacology and use:
Nelfinavir is a protease inhibitor with activity against Human Immunodeficiency Virus Type 1 (HIV-1). Protease inhibitors block the part of HIV called protease. HIV-1 protease is an enzyme required for the proteolytic cleavage of the viral polyprotein precursors into the individual functional proteins found in infectious HIV-1. Nelfinavir binds to the protease active site and inhibits the activity of the enzyme. This inhibition prevents cleavage of the viral polyproteins resulting in the formation of immature non-infectious viral particles. Protease inhibitors are almost always used in combination with at least two other anti-HIV drugs. For the treatment of HIV infection.

Mechanism Of Action:
Nelfinavir inhibits the HIV viral proteinase enzyme which prevents cleavage of the gag-pol polyprotein, resulting in noninfectious, immature viral particles.

News Articles on Nelfinavir

SEXUALLY TRANSMITTED DISEASES:- THEIR NATURE AND CURE - THIRD PUBLICATION  -  ‎Dec 18, 2009‎
Didanosine, Efavirenz, Lamivudine, Stavudine, Indinavir, Nelfinavir, Abalavir. Eminence Consult Natural Medicine destroys HIV and cures AIDS. ... Modern Ghana

Coalescing purpuric plaques  -  ‎Nov 10, 2009‎
His medications included Combivir (lamivudine/zidovudine) and nelfinavir. A biopsy revealed increased spindle cells with vascular slits. ... Clinical Advisor

Market Watch  -  ‎Nov 5, 2009‎
...ketoconazole, atazanavir, clarithromycin, indinavir, itraconazole, nefazodone, nelfinavir, ritonavir, saquinavir, or telithromycin). ... The Hospitalist Online

New drug for type 2 diabetes  -  ‎Oct 29, 2009‎
Interactions: Potentiated by strong CYP3A4/5 inhibitors (eg, ketoconazole, atazanavir, clarithromycin, indinavir, itraconazole, nefazodone, nelfinavir, ... Clinical Advisor

How antiretroviral therapy prolongs life  -  ‎Oct 21, 2009‎
...ritonavir and nelfinavir prevent the cutting of the precursor polypeptide that is processed into smaller core proteins. l Entry inhibitors: these drugs ... The Southern Times

AIDS Drugs May Help Against Cancer, Too  -  Sep 18, 2007
Nelfinavir was also found to be effective against breast cancer cells that are resistant to ... The scientists also tested nelfinavir in mice that had been ... New York Times

HIV Drug Might Fight Cancer  -  Sep 1, 2007
Based on this new finding, the HIV protease inhibitor nelfinavir is being ... The researchers hit upon the idea of testing nelfinavir and other protease ... Washington Post

Nelfinavir (Viracept) recalled in UK and Europe following contaminatio...  -  Jun 6, 2007
Drug company, Roche, the UK's Medicines and Healthcare products Regulatory Agency (MHRA) and the European Medicines Agency (EMEA) issued alerts tonight ... Aidsmap

Nelfinavir and nevirapine well tolerated during pregnancy  -  May 9, 2005
HAART regimens containing either the protease inhibitor nelfinavir or the NNRTI nevirapine are well tolerated during pregnancy, according to a Dutch study ... Aidsmap

Warning Issued on Nelfinavir (Viracept) for Children and Pregnant …  -  Sep 10, 2007
By Michael Smith, Senior Staff Writer, MedPage Today. NEW YORK, Sept. 10 -- In the wake of a recall in Europe of nelfinavir (Viracept) because of a ... MedPage Today

Learn about Nelfinavir from Consumer Reports Health.  -  Jan 1, 2008
Nelfinavir is used in combination with other medications to treat human immunodeficiency virus (HIV) infection in patients with or without acquired ... consumerreports.org

… and Pharmacodynamics of Efavirenz and Nelfinavir in HIV-infected …  -  Mar 27, 2007
Efavirenz and nelfinavir doses were adjusted to achieve AUC values of ... Efavirenz and nelfinavir oral clearance increased 37 and 62% from weeks 2 to 56, ... Nature.com

Nelfinavir (Systemic).(Drug overview)  -  Aug 1, 2006
Nelfinavir ( nel-FIN-a-veer) is used, usually in combination with other medicines, in the treatment of the infection caused by the human immunodeficiency ... Free with registration - USP DI-Volume II, Advice for the... - AccessMyLibrary.com

Nelfinavir (Systemic).  -  Feb 1, 2006
Nelfinavir ( nel-FIN-a-veer) is used, usually in combination with other medicines, in the treatment of the infection caused by the human immunodeficiency ... Free with registration - USP DI-Volume II, Advice for the... - AccessMyLibrary.com

Nelfinavir Acts in HIV-Infected Neonates as in Adults, But Individual...  -  Feb 7, 2008
By Maria Bishop. BOSTON, MA -- February 7, 2008 -- Adequate exposure to nelfinavir is undetermined for neonates diagnosed with HIV in the first 2 weeks of ... DG News

AIDS drug shows potential as weapon against cancer  -  Aug 31, 2007
The most effective of the drugs was nelfinavir, sold by Roche Holding AG (ROG.VX) as Viracept, the researchers said. The drug also slowed the growth of both ... Reuters

HIV/AIDS Therapy; Nelfinavir induces adipocyte necrosis by oxidative ...  -  Mar 20, 2005
..."Protease inhibitor treatment strongly diminishes mortality in HIV-infected patients. This treatment has also been associated with lipodystrophy and has ... Pay-Per-View - Medical Devices & Surgical Technology... - Factiva, from Dow Jones

Taking Nelfinavir from Consumer Reports Health.  -  Jan 1, 2008
Nelfinavir may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:. If high blood sugar is not treated, a serious, ... consumerreports.org

Roche says Viracept licence in Europe re-instated  -  Sep 20, 2007
..."Roche fully intends to re-supply Viracept (nelfinavir) once the suspension is lifted," the company said. "However, it may take a few months for Viracept to ... Reuters

… ; HIV-infected newborns may need higher nelfinavir dose than FDA …  -  Apr 26, 2006
..."As a relationship between nelfinavir antiretroviral efficacy and plasma concentrations has been previously established, nelfinavir pharmacokinetics" were ... Pay-Per-View - Immunotherapy Weekly - Factiva, from Dow Jones

Drug Safety; Low-dose ritonavir added to nelfinavir regimen is safe...  -  Nov 29, 2005
2005 NOV 29 - (NewsRx.com) -- Low-dose ritonavir added to a nelfinavir regimen is safe in HIV-infected patients. In a recent report, researchers in Denmark ... Pay-Per-View - Life Science Weekly - Factiva, from Dow Jones

HIV Protease Inhibitor Nelfinavir Being Tested in Cancer  -  Sep 6, 2007
September 6, 2007 — The human immunodeficiency virus (HIV) protease inhibitor nelfinavir ( Viracept, Pfizer) has shown anticancer activity in cell cultures ... Medscape

Nelfinavir Added to Chemotherapy Shows Promise for Pancreatic Cancer  -  Jun 24, 2008
NEW YORK JUN 24, 2008 (Reuters Health) - A combination of the protease inhibitor nelfinavir and a conventional chemotherapy regimen of gemcitabine and ... Cancerpage.com

… ; HIV-infected newborns may need higher nelfinavir dose than FDA …  -  Apr 24, 2006
..."As a relationship between nelfinavir antiretroviral efficacy and plasma concentrations has been previously established, nelfinavir pharmacokinetics" were ... Pay-Per-View - AIDS Weekly - Factiva, from Dow Jones

HIV/AIDS Therapy; CYP2C19 converts nelfinavir to a bioactive metabolit...  -  Feb 18, 2005
However, the protease inhibitor nelfinavir (Viracept) is metabolized mainly to nelfinavir hydroxy-t-butylamide (M8), which exhibits potent antiviral ... Pay-Per-View - Drug Week - Factiva, from Dow Jones

Kenya: HIV Patients Suffer As Drug is Recalled  -  Aug 9, 2007
The drug, whose generic name is Nelfinavir, is considered to be an important defence against HIV and is used by patients who don't respond to first-line ... AllAfrica.com

HIV/AIDS Therapy; CYP2C19 converts nelfinavir to a bioactive metabolit...  -  Feb 14, 2005
However, the protease inhibitor nelfinavir (Viracept) is metabolized mainly to nelfinavir hydroxy-t-butylamide (M8), which exhibits potent antiviral ... Pay-Per-View - AIDS Weekly - Factiva, from Dow Jones

… ; HIV-infected newborns may need higher nelfinavir dose than FDA …  -  Apr 28, 2006
..."As a relationship between nelfinavir antiretroviral efficacy and plasma concentrations has been previously established, nelfinavir pharmacokinetics" were ... Pay-Per-View - Drug Week - Factiva, from Dow Jones

HIV/AIDS Therapy; CYP2C19 converts nelfinavir to a bioactive metabolit...  -  Feb 14, 2005
However, the protease inhibitor nelfinavir (Viracept) is metabolized mainly to nelfinavir hydroxy-t-butylamide (M8), which exhibits potent antiviral ... Pay-Per-View - Anti-Infectives Week - Factiva, from Dow Jones

DRUG CAPSULE WHAT YOU SHOULD KNOW  -  Aug 28, 2006
...or non-prescription/herbal products, particularly aluminum- and magnesium-containing antacids, digoxin, live vaccines, lovastatin, nelfinavir, warfarin. $2.95 - Milwaukee Journal Sentinel - NewsBank

HIV/AIDS Therapy; CYP2C19 converts nelfinavir to a bioactive metabolit...  -  Feb 14, 2005
However, the protease inhibitor nelfinavir (Viracept) is metabolized mainly to nelfinavir hydroxy-t-butylamide (M8), which exhibits potent antiviral ... Pay-Per-View - Hematology Week - Factiva, from Dow Jones

… to temporary suspension of nelfinavir's (Viracept) European...  -  Jun 21, 2007
The license for nelfinavir (Viracept) has been temporarily suspended by European drug ... Roche, the manufacturer of nelfinavir announced that following ... Aidsmap

HIV/AIDS Therapy; CYP2C19 converts nelfinavir to a bioactive metabolit...  -  Feb 19, 2005
However, the protease inhibitor nelfinavir (Viracept) is metabolized mainly to nelfinavir hydroxy-t-butylamide (M8), which exhibits potent antiviral ... Pay-Per-View - Obesity, Fitness & Wellness Week - Factiva, from Dow Jones

… Drug Reaction; Step-wise intervention effectively manages nelfinavi...  -  Jan 2, 2006
Keywords: Toronto, Ontario, Canada, HIV/AIDS, Nelfinavir, Diarrhea, Drug Side Effect, Step-Wise Intervention. This article was prepared by AIDS Weekly ... Pay-Per-View - AIDS Weekly - Factiva, from Dow Jones

HIV/AIDS Therapy; CYP2C19 converts nelfinavir to a bioactive metabolit...  -  Feb 14, 2005
However, the protease inhibitor nelfinavir (Viracept) is metabolized mainly to nelfinavir hydroxy-t-butylamide (M8), which exhibits potent antiviral ... Pay-Per-View - Health & Medicine Week - Factiva, from Dow Jones

IAS: Roche admits long-standing low-level contamination of nelfinavir  -  Jul 26, 2007
Nelfinavir (Viracept) manufacturer, Roche, has admitted that some batches of the now-withdrawn protease inhibitor have been contaminated with unacceptable ... Aidsmap

HIV/AIDS Therapy; CYP2C19 converts nelfinavir to a bioactive metabolit...  -  Feb 20, 2005
However, the protease inhibitor nelfinavir (Viracept) is metabolized mainly to nelfinavir hydroxy-t-butylamide (M8), which exhibits potent antiviral ... Pay-Per-View - Medical Devices & Surgical Technology... - Factiva, from Dow Jones

Recall of Viracept (Nelfinavir)  -  Jun 8, 2007
Pharmaceutical company Roche is taking responsible action with its voluntary recall of the anti-HIV treatment nelfinavir (Viracept), says government ... scoop.co.nz

HIV/AIDS Therapy; CYP2C19 converts nelfinavir to a bioactive metabolit...  -  Feb 14, 2005
However, the protease inhibitor nelfinavir (Viracept) is metabolized mainly to nelfinavir hydroxy-t-butylamide (M8), which exhibits potent antiviral ... Pay-Per-View - Hepatitis Weekly - Factiva, from Dow Jones

… University Medical Center; CYP2C19 converts nelfinavir to a...  -  Feb 16, 2005
However, the protease inhibitor nelfinavir (Viracept) is metabolized mainly to nelfinavir hydroxy-t-butylamide (M8), which exhibits potent antiviral ... Pay-Per-View - Biotech Week - Factiva, from Dow Jones

Near-global nelfinavir (Viracept) recall 'very difficult situation'  -  Jun 20, 2007
The World Health Organization (WHO), drug companies, drug regulators, NGOs and national governments have been working together to minimise the disruption of ... Aidsmap

HIV/AIDS Therapy; Nelfinavir induces adipocyte necrosis by oxidative ...  -  Mar 14, 2005
..."Protease inhibitor treatment strongly diminishes mortality in HIV-infected patients. This treatment has also been associated with lipodystrophy and has ... Pay-Per-View - AIDS Weekly - Factiva, from Dow Jones

Nelfinavir (Viracept) recall update  -  Jun 7, 2007
Roche is recalling all nelfinavir (Viracept) manufactured at its Swiss plant with immediate effect. Patients who are currently taking nelfinavir are advised ... Aidsmap

AIDS Drug Recall Hits Poorest Patients  -  Aug 2, 2007
Viracept (generic name Nelfinavir), a medicine for the control and treatment of AIDS which is manufactured by the Swiss laboratory Roche. ... NPR

HIV/AIDS Therapy; Nelfinavir induces adipocyte necrosis by oxidative ...  -  Mar 18, 2005
..."Protease inhibitor treatment strongly diminishes mortality in HIV-infected patients. This treatment has also been associated with lipodystrophy and has ... Pay-Per-View - Drug Week - Factiva, from Dow Jones

Sida: résultats toxicologiques rassurants pour les patients traités...  -  Jul 25, 2008
La contamination était intervenue lors de la production de la substance active, le nelfinavir, utilisée pour la fabrication du médicament. ... Le Point

Depo-medroxyprogesterone in Women on Antiretroviral Therapy: …  -  Dec 27, 2006
Minor changes in nelfinavir and nevirapine drug exposure were seen after DMPA, ... Drug exposure (AUC 0–12 h) to nelfinavir was reduced with minimal changes ... Nature.com

… /AIDS Therapy; Pharmacokinetic established for nelfinavir and its...  -  Apr 25, 2005
2005 APR 25 - (NewsRx.com) -- Pharmacokinetics was established for nelfinavir and its active metabolite in HIV-1-infected infants. ... Pay-Per-View - AIDS Weekly - Factiva, from Dow Jones

Studies conclude impurity in Roche's Viracept did not increase...  -  Jul 24, 2008
The discovery of the EMS impurity in some batches of nelfinavir led to a global recall of this HIV medication in June 2007. Since then, the product has been ... eurekalert.org

… /AIDS Therapy; C/EBP alpha reverses anti-adipogenic effects of...  -  Apr 4, 2005
According to recent research from the United States, "Nelfinavir and other HIV protease ... "We report here that nelfinavir promotes loss of cytoplasmic ... Pay-Per-View - AIDS Weekly - Factiva, from Dow Jones

… ; Higher viral load/lower age correlate to nelfinavir-related L90M...  -  Feb 18, 2005
..."To assess prevalence of nelfinavir resistance mutations in children receiving highly active antiretroviral therapy, sequencing of protease gene from plasma ... Pay-Per-View - Genomics & Genetics Weekly - Factiva, from Dow Jones

… ; Higher viral load/lower age correlate to nelfinavir-related L90M...  -  Feb 14, 2005
..."To assess prevalence of nelfinavir resistance mutations in children receiving highly active antiretroviral therapy, sequencing of protease gene from plasma ... Pay-Per-View - Hematology Week - Factiva, from Dow Jones

… /AIDS Therapy; Pharmacokinetic established for nelfinavir and its...  -  Apr 29, 2005
2005 APR 29 - (NewsRx.com) -- Pharmacokinetics was established for nelfinavir and its active metabolite in HIV-1-infected infants. ... Pay-Per-View - Drug Week - Factiva, from Dow Jones

… ; Higher viral load/lower age correlate to nelfinavir-related L90M...  -  Feb 16, 2005
..."To assess prevalence of nelfinavir resistance mutations in children receiving highly active antiretroviral therapy, sequencing of protease gene from plasma ... Pay-Per-View - Biotech Week - Factiva, from Dow Jones

… /AIDS Therapy; C/EBP alpha reverses anti-adipogenic effects of...  -  Apr 8, 2005
According to recent research from the United States, "Nelfinavir and other HIV protease ... "We report here that nelfinavir promotes loss of cytoplasmic ... Pay-Per-View - Genomics & Genetics Weekly - Factiva, from Dow Jones

European licence for Roche HIV drug Viracept re-established by …  -  Oct 19, 2007
Viracept (nelfinavir), a protease inhibitor is supplied by Roche outside the US, Canada and Japan. Viracept was first introduced by Roche in 1999. ... Le fermenteur à bioréaction

Press Release: Studies Assessed by European Health Authority …  -  Jul 24, 2008
The discovery of the EMS impurity in some batches of nelfinavir led to a global recall of this HIV medication in June 2007. Since then, the product has been ... Pay-Per-View - PR Newswire Europe - HighBeam Research

… Research; The pharmacokinetics of nelfinavir change in HCV and HIV...  -  Apr 11, 2005
According to recent research from Italy, "in order to evaluate the potential risk of nelfinavir (NFV) accumulation in human immunodeficiency virus ... Pay-Per-View - Health & Medicine Week - Factiva, from Dow Jones

European Licence For Roche HIV Drug Viracept Recommended For Re …  -  Oct 1, 2007
Roche fully intends to re supply Viracept (nelfinavir) once the ... Viracept (nelfinavir), a protease inhibitor is supplied by Roche outside the US, ... Medical News Today - Medical News Today (press release)

EC Reinstates License for Roche's Viracept  -  Oct 22, 2007
The timing of Viracept's (nelfinavir) reintroduction will vary in each country. It is likely to be a few months before the drug is available fully, ... FDA news - FDA news (subscription)

Governo pede que pessoas não deixem de tomar Nelfinavir  -  Jun 8, 2007
BRAS�LIA - Enquanto providencia a substituição do remédio do coquetel antiaids Nelfinavir, que está sendo recolhido mundialmente pelo Laboratório Roche por ... O Globo

HCV/HIV coinfection guidelines may lead to unnecessarily premature …  -  Sep 26, 2005
In contrast, participants on nelfinavir had mean 23.3% increases of HCV viral ... In fact, five of eleven nelfinavir-treated coinfected patients with CD4 ... Aidsmap

HIV Protease Inhibitors Show Potential As Cancer Treatments  -  Sep 8, 2007
In this study, nelfinavir and saquinavir were more potent than the other HIV ... Nelfinavir was the most effective of all the protease inhibitors tested, ... emaxhealth.com

Vervuilde nelfinavir was niet kankerverwekkend  -  Sep 2, 2008
De vervuilde nelfinavir die vorig jaar van de markt is gehaald, blijkt niet kankerverwekkend geweest te zijn. Dat blijkt uit een verklaring van het ... Hiv Vereniging Nederland

HIV/AIDS Therapy; Researchers' work adds to HIV/AIDS therapy body of ...  -  Apr 4, 2005
Study 1: CYP2C19 converts nelfinavir to a bioactive metabolite. ... However, the protease inhibitor nelfinavir (Viracept) is metabolized mainly to ... Pay-Per-View - Hepatitis Weekly - Factiva, from Dow Jones

HIV/AIDS Therapy; Researchers provide details of new studies and …  -  Apr 18, 2005
Study 2: CYP2C19 converts nelfinavir to a bioactive metabolite. ... However, the protease inhibitor nelfinavir (Viracept) is metabolized mainly to ... Pay-Per-View - Diabetes Week - Factiva, from Dow Jones

HIV/AIDS Therapy; Researchers provide details of new studies and …  -  Apr 18, 2005
Study 2: CYP2C19 converts nelfinavir to a bioactive metabolite. ... However, the protease inhibitor nelfinavir (Viracept) is metabolized mainly to ... Pay-Per-View - AIDS Weekly - Factiva, from Dow Jones

HIV/AIDS Therapy; Researchers provide details of new studies and …  -  Apr 23, 2005
Study 2: CYP2C19 converts nelfinavir to a bioactive metabolite. ... However, the protease inhibitor nelfinavir (Viracept) is metabolized mainly to ... Pay-Per-View - Obesity, Fitness & Wellness Week - Factiva, from Dow Jones

HIV/AIDS Therapy; Researchers' work adds to HIV/AIDS therapy body of ...  -  Apr 4, 2005
Study 1: CYP2C19 converts nelfinavir to a bioactive metabolite. ... However, the protease inhibitor nelfinavir (Viracept) is metabolized mainly to ... Pay-Per-View - AIDS Weekly - Factiva, from Dow Jones

HIV/AIDS Therapy; Researchers provide details of new studies and …  -  Apr 18, 2005
Study 2: CYP2C19 converts nelfinavir to a bioactive metabolite. ... However, the protease inhibitor nelfinavir (Viracept) is metabolized mainly to ... Pay-Per-View - Obesity & Diabetes Week - Factiva, from Dow Jones

HIV/AIDS Therapy; Researchers' work adds to HIV/AIDS therapy body of ...  -  Apr 7, 2005
Study 1: CYP2C19 converts nelfinavir to a bioactive metabolite. ... However, the protease inhibitor nelfinavir (Viracept) is metabolized mainly to ... Pay-Per-View - Blood Weekly - Factiva, from Dow Jones

HIV/AIDS Therapy; Researchers provide details of new studies and …  -  Apr 18, 2005
Study 2: CYP2C19 converts nelfinavir to a bioactive metabolite. ... However, the protease inhibitor nelfinavir (Viracept) is metabolized mainly to ... Pay-Per-View - Proteomics Weekly - Factiva, from Dow Jones

HIV/AIDS Therapy; Researchers provide details of new studies and …  -  Apr 20, 2005
Study 2: CYP2C19 converts nelfinavir to a bioactive metabolite. ... However, the protease inhibitor nelfinavir (Viracept) is metabolized mainly to ... Pay-Per-View - Immunotherapy Weekly - Factiva, from Dow Jones

HIV/AIDS Therapy; Researchers' work adds to HIV/AIDS therapy body of ...  -  Apr 10, 2005
Study 1: CYP2C19 converts nelfinavir to a bioactive metabolite. ... However, the protease inhibitor nelfinavir (Viracept) is metabolized mainly to ... Pay-Per-View - Medical Devices & Surgical Technology... - Factiva, from Dow Jones

HIV/AIDS Therapy; Researchers provide details of new studies and …  -  Apr 18, 2005
Study 2: CYP2C19 converts nelfinavir to a bioactive metabolite. ... However, the protease inhibitor nelfinavir (Viracept) is metabolized mainly to ... Pay-Per-View - Health & Medicine Week - Factiva, from Dow Jones

HIV/AIDS Therapy; Researchers provide details of new studies and …  -  Apr 24, 2005
Study 2: CYP2C19 converts nelfinavir to a bioactive metabolite. ... However, the protease inhibitor nelfinavir (Viracept) is metabolized mainly to ... Pay-Per-View - Medical Devices & Surgical Technology... - Factiva, from Dow Jones

Hackensack University Medical Center; Researchers' work adds to HIV/ …  -  Apr 6, 2005
Study 1: CYP2C19 converts nelfinavir to a bioactive metabolite. ... However, the protease inhibitor nelfinavir (Viracept) is metabolized mainly to ... Pay-Per-View - Biotech Week - Factiva, from Dow Jones

HIV/AIDS Therapy; Researchers' work adds to HIV/AIDS therapy body of ...  -  Apr 4, 2005
Study 1: CYP2C19 converts nelfinavir to a bioactive metabolite. ... However, the protease inhibitor nelfinavir (Viracept) is metabolized mainly to ... Pay-Per-View - Anti-Infectives Week - Factiva, from Dow Jones

Nelfinavir is weer verkrijgbaar  -  Jul 1, 2008
De proteaseremmer nelfinavir is weer verkrijgbaar. Vorig jaar juli werd er een vervuiling in sommige productiebatches van nelfinavir gevonden, waardoor het ... Hiv Vereniging Nederland

Article: Recall of HIV drug leaves poor with little choiceSubstitutes...  -  Jul 23, 2007
Batches of Roche's HIV protease inhibitor Viracept (nelfinavir) are being ... Viracept (nelfinavir), a leading PI is supplied by Roche outside the US and ... Pay-Per-View - International Herald Tribune - HighBeam Research

Retiran del mercado mexicano el antirretroviral Nelfinavir  -  Jun 12, 2007
Laboratorios Roche anunció ayer su decisión de retirar del mercado mexicano el medicamento Nelfinavir, de nombre comercial Viracept, debido a que en algunos ... La Jornada - La Jornada (México)

Remise à disposition de Viracept® (nelfinavir) pour le traitement de...  -  Oct 28, 2008
Depuis le 19 octobre, l'antiprotéase Viracept® (nelfinavir), sous forme de comprimés et de poudre orale, est remis à disposition dans les pharmacies par le ... Femmes et sida

Kaletra not associated with raised blood pressure, manufacturer...  -  Oct 30, 2006
The second was in 155 treatment-naïve people randomised to receive either Kaletra plus zidovudine and lamivudine or nelfinavir plus zidovudine and ... Aidsmap

Saúde suspende uso do Nelfinavir no Ceará  -  Jun 12, 2007
O medicamento Nelfinavir, usado na terapia de pessoas infectadas pelo HIV, foi retirado de circulação no Ceará e demais estados da Federação, ... Diário do Nordeste - Diário do Nordeste (Assinatura)

CROI: Saquinavir-based combination prevents mother-to-child HIV …  -  Feb 22, 2006
One woman switched from ritonavir-boosted saquinavir to nelfinavir after ten days ... This occurred in the nelfinavir group in a woman whose viral load was ... Aidsmap

Contamination de Viracept® (nelfinavir) par l'éthylmésylate : pas d' …  -  Aug 12, 2008
En juin 2007, les Autorités de santé européennes suspendaient temporairement l'autorisation de mise sur le marché de Viracept® (nelfinavir) en raison d'une ... Femmes et sida

Long-term complete remission of laryngeal Kaposi's sarcoma after …  -  Mar 24, 2005
11 The drug combination used in this case followed an institutional protocol: didanosine, an inosine antimetabolite; nelfinavir, an HIV protease inhibitor; ... Nature.com

UNIÃO EUROPÉIA SUSPENDE VENDAS DO REMÉDIO ANTI-AIDS …  -  Aug 7, 2007
O Viracept (mesilato de nelfinavir) também foi recolhido no Brasil em junho, por iniciativa da Roche. A comissão disse que o anúncio baseou-se nas ... G1.com.br

Usado no coquetel anti-HIV, Mesilato de Nelfinavir contém impurezas  -  Jun 8, 2007
Rio - Todos os pacientes que fazem uso do medicamento Mesilato de Nelfinavir (Viracept) contra HIV devem procurar os serviços de saúde onde fazem tratamento ... O Dia Online

Descubren un posible cancerígeno en un medicamento contra el sida  -  Sep 11, 2007
El 'Viracept', cuyo nombre genérico es 'nelfinavir', pertenece al grupo de medicamentos contra el sida llamados inhibidores de proteasa que son cruciales en ... La Vanguardia

La retirada de uno de los antirretrovirales más usados, un drama en...  -  Jul 24, 2007
La retirada del mercado de todas las formulaciones del nelfinavir afecta a todo el mundo salvo a Estados Unidos, Canadá y Japón, donde no se habrían ... El Diario Montañés

醫管局已è?¯çµ¡ç›¸é—œç—…人å?œæœ?Nelfinavir  -  Jun 7, 2007
...醫管局表示, 知悉羅æ°?藥廠在香港自願全é?¢å›žæ”¶æ‰€æœ‰æ‰¹è™Ÿçš„Nelfinavir 藥物, 已通知 公立醫院å?³æ™‚å?œæ­¢ä½¿ç”¨æœ‰é—œè—¥ç‰©ï¼Œ 亦陸續è?¯çµ¡ç?²è™•方的約40 å??專科門診病人å?³æ™‚å?œæ­¢ ... 香港電å?° - 香港電å?°

Lopinavir/ritonavir not linked to hepatotoxicity regardless of HCV...  -  Jan 25, 2005
About 75% were male, but there were more women (31%) in the nelfinavir group. Median age was about 37 years. About three-quarters were black and about ... Aidsmap

Retrait de lots de Viracept® (nelfinavir)  -  Jun 6, 2007
L'Afssaps a été informée par les laboratoires Roche d'une contamination par une impureté chimique lors de la production de Viracept® (nelfinavir). ... survivreausida.net

Brasil retira medicina contra sida  -  Jun 8, 2007
Roche informó el miércoles pasado que lotes del medicamento Nelfinavir ... Simao dijo que el Nelfinavir es distribuido actualmente en Brasil a cerca de 9000 ... CNNExpansión.com

Pharmazeutische Zeitung online: Nachrichtenarchiv  -  Apr 11, 2008
Nach dem Rückruf des HIV-Mittels Viracept ® (Nelfinavir) aufgrund von ... Der Proteaseinhibitor Nelfinavir ist ein Virenhemmer der ersten Generation. ... Pharmazeutische Zeitung online

HN78 Nelfinavir en atazanavir  -  Jul 10, 2007
In een oude trial werd atazanavir met nelfinavir vergeleken, gedurende 76 weken. Alle deelnemers kregen daarnaast d4T + 3TC. De deelnemers die nelfinavir ... Hiv Vereniging Nederland

Algunas drogas contra el VIH podrían ser antitumorales  -  Sep 6, 2007
Los dos antivirales más potentes en la investigación fueron nelfinavir y saquinavir que lograron, según el estudio, frenar el crecimiento tumoral y acelerar ... Télam

Drogas antisida serían eficaces contra el cáncer  -  Sep 7, 2007
Descubrieron así que tres de las seis drogas -nelfinavir, ritonavir y ... Los dos antivirales más potentes fueron el nelfinavir y el saquinavir: no sólo ... Clarín.com

Alerta y retiro de fármaco contra Sida  -  Jun 9, 2007
Las autoridades del Minsa retiraron de las unidades de salud del país el fármaco Viracept --también conocido como Nelfinavir--, tras descubrirse lotes de ... El Nuevo Diario

Roche retirará droga antisida por impureza en químicos  -  Jun 9, 2007
El fármaco contra el virus del sida Viracept (nelfinavir), de la compañía farmacéutica suiza Roche, se retirará del mercado costarricense como medida ... La Nación Costa Rica

CCSS garantiza medicina contra sida  -  Jul 15, 2007
La Caja Costarricense de Seguro Social (CCSS) garantiza que sus farmacias cuentan con Nelfinavir, un medicamento antirretroviral para los enfermos de sida. ... La Nación Costa Rica

本港逾120 人æœ?用回收抗愛滋病藥  -  Jun 7, 2007
...瑞士羅æ°?藥廠宣布回收一種抗愛滋病藥Viracept ( è—¥å??nelfinavir ) , 因為部份å?— 化學å“?污染, 有å?¯èƒ½è‡´ç™Œã€‚ 本港衛生署表示, 這藥00 年在港註冊, 屬醫生處方藥物, ... 香港電å?° - 香港電å?°

Nelfinavir komt terug op de markt  -  Nov 8, 2007
Nelfinavir mag weer gebruikt worden. De schorsing van de registratie is ingetrokken. Dit betekent dat het middel weer geproduceerd kan worden en naar ... Hiv Vereniging Nederland

:: Agência de Notícias da Aids ::  -  Apr 23, 2008
Mariângela Simão, informou também que a farmacêutica Roche vai conduzir uma pesquisa no Brasil com gestantes que utilizaram o Nelfinavir. ... Agência de Notícias da Aids

Brand Names/Synonyms:
Nelfinavir is also known by the following brand names and/or synonyms1UN; AG1346; NELFINAVIR MESYLATE AG1343; NFV; NLF; Nelfinavir; Nelfinavir Mesylate; Nelfinavir [Inn:Ban]; Viracept

Drug Category:
Nelfinavir is categorized under the following by the FDA: Anti-HIV Agents; HIV Protease Inhibitors; ATC:J05AE04

Dosage Forms:
Tablets, Oral powder

Absorption:
Well absorbed

Interactions:
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Chemical IUPAC Name:
2-[2-hydroxy-3-(3-hydroxy-2-methyl-benzoyl)amino-4-phenylsulfanyl-butyl]-N-tert-butyl-1,2,3,4,4a,5,6,7,8,8a-decahydroisoquinoline-3-carboxamide





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