Nevirapine

This page contains recent news articles, when available, and an overview of Nevirapine but does not offer medical advice. You should contact your physician with regard to any health issues or concerns.


Overview:

Nevirapine
(when available)

Pharmacology and use:
Nevirapine is a non-nucleoside reverse transcriptase inhibitor (nNRTI) with activity against Human Immunodeficiency Virus Type 1 (HIV-1). HIV-2 RT and eukaryotic DNA polymerases (such as human DNA polymerases alpha, beta, or sigma) are not inhibited by nevirapine. Nevirapine is, in general, only prescribed after the immune system has declined and infections have become evident. It is always taken with at least one other HIV medication such as Retrovir or Videx. The virus can develop resistance to nevirapine if the drug is taken alone, although even if used properly, nevirapine is effective for only a limited time. For use in combination with other antiretroviral drugs in the ongoing treatment of HIV-1 infection.

Mechanism Of Action:
Nevirapine binds directly to reverse transcriptase (RT) and blocks the RNA-dependent and DNA-dependent DNA polymerase activities by causing a disruption of the enzyme's catalytic site. The activity of nevirapine does not compete with template or nucleoside triphosphates.

News Articles on Nevirapine

New resistance becoming rarer as more patients achieve undetectable HIV viral load  -  05 Jan 2010
Older drugs from the NNRTI class (efavirenz and nevirapine) are the antiretroviral agents most vulnerable to resistance. “However even for this drug class�, ... Aidsmap

South Africa: Urban Women Bear Brunt of Aids in KZN  -  ‎Dec 13, 2009‎
Interestingly, the study showed that nevirapine alone was relatively ineffective at preventing mothers from infecting their babies. Since 2002, pregnant HIV ... AllAfrica.com

RIP the health minister who cost thousands of lives  -  ‎Dec 16, 2009‎
She fought an application in the Constitutional Court for the roll-out of nevirapine, then the leading drug for the prevention of mother-to-child Aids ... Times LIVE

Pune college study gets WHO nod  -  ‎Dec 15, 2009‎
The study -- Six-Week Extended Dose of Nevirapine (SWEN) -- was conducted between February 2002 and March 2007. The WHO made the revisions on November 30 ... Daily News & Analysis

TB, pregnancy, most common reasons for treatment changes in African study  -  ‎Dec 10, 2009‎
The finding calls attention to the dilemma facing physicians who need to decide whether to prescribe nevirapine (Viramune) or efavirenz (Sustiva), ... Aidsmap

Most NNRTI-experienced patients in southern Africa will benefit from etravirine  -  ‎Dec 17, 2009‎
Nearly all patients in southern Africa who have received treatment with the NNRTIs efavirenz or nevirapine would benefit from therapy with etravirine, ... Aidsmap

Should Health activists take fund from pharmaceuticals?  -  ‎Dec 12, 2009‎
It is a drug called nevirapine and we had the support from the manufacturers of nevirapine to do those studies. Now that is openly acknowledged, ... The New Nation

AIDS control staff intensify strike  -  ‎Dec 22, 2009‎
...“The HIV positive patients, who are dependent on ART and nevirapine, are suffering due to non-availability of counselling. ... Sakaal Times

Mali gets tool to detect bogus medicine  -  ‎Dec 31, 2009‎
...the HIV therapy of lamivudine, zidovudine and nevirapine; anti-malarial quinidine; and the antibiotic rifampicin, to treat tuberculosis and leprosy. ... UPI.com

Mumbai city newborns, mums lack HIV shield  -  ‎Dec 28, 2009‎
Also, an hour before delivery, the mother is given a dose of Nevirapine, a common drug, to lessen the chances of transmission of the disease to the newborn. ... Daily News & Analysis

Tshabalala-Msimang 'an undisputed hero'  -  ‎Dec 22, 2009‎
She was criticised for delaying the roll-out of antiretroviral drugs and nevirapine to HIV- positive patients and promoting unscientific remedies including ... Business Day

Manto misinformation  -  ‎Dec 23, 2009‎
In 2002 South Africa's High Court ordered the government to make the drug nevirapine available to pregnant women to help prevent mother to child ... News24

HIV Positive cases rise in Volta Region  -  ‎Dec 16, 2009‎
It said of the pregnant women, 319 were attending Ante-Natal Clinic (ANC) and receiving Nevirapine, a drug meant to prevent mother-to-child transmission of ... Ghana News Agency

Volta Region records more HIV cases in 2009  -  ‎Dec 17, 2009‎
Out of this number 319 are attending Ante-Natal Clinic (ANC) and receiving Nevirapine, a drug meant to prevent mother-to-child transmission of the virus. ... Ghana News Agency

Rotary Club contributes to AIDS relief for African children  -  ‎Dec 16, 2009‎
...efforts in Liberia using counseling, treatment and the medication Nevirapine to halt mother-to-child transmission of HIV during the birth process. ... Los Altos Town Crier

South Africa: Improved PMTCT yields dramatic results  -  ‎Dec 10, 2009‎
But a 2005 study found that on the nevirapine-only regimen, one in five HIV-positive mothers were still transmitting the virus to their infants. ... ReliefWeb (press release)

A big year for our justice system  -  ‎Dec 20, 2009‎
He also gave advocate Geoff Budlender hell about his comments regarding the Nevirapine case, conveniently managing to mention that he was the opposing ... The Daily Maverick

SEXUALLY TRANSMITTED DISEASES:- THEIR NATURE AND CURE - THIRD PUBLICATION  -  ‎Dec 18, 2009‎
Examples of Anti-retroviral drugs are: Zidovudine (AZT or 31 Azido 31 deoxy thymidine) or retrovir, Nevirapine, Didanosine, Efavirenz, Lamivudine, ... Modern Ghana

Soldiers being tortured to death at Harare army barracks  -  14 Nov 2009
According to official reports, Samudzi allegedly carried three packets containing cotrimoxazole, aspirin and nevirapine tablets in his left trousers pocket. ... ZimEye

Combination Antiretroviral Therapy Effective At Reducing HIV Resistance In ...  -  ‎Oct 27, 2009‎
Such resistance can compromise later treatment regimens that include the same class of drug as nevirapine. The researchers report that the combination drug ... Science Daily (press release)

HLA-Cw*04 allele associated with nevirapine-induced rash in HIV-infected Thai ...  -  ‎Oct 22, 2009‎
A high incidence of rash has been reported in HIV-1 patients who received the anti-retroviral drug nevirapine. In addition, several studies have suggested ... 7thSpace Interactive (press release)

Improving the coverage of the PMTCT programme through a participatory quality ...  -  ‎Nov 5, 2009‎
Coverage of CD4 testing increased from 40 to 97%, uptake of maternal nevirapine from 57 to 96%, uptake of infant nevirapine from 15 to 68% and six week PCR ... 7thSpace Interactive (press release)

Harare. 120 soldiers are being tortured.  -  ‎Nov 12, 2009‎
Samudzi allegedly carried three packets containing cotrimohazole aspirin and nevirapine in his left trousers pocket.� But The Zimbabwe Times says “It was, ... Times LIVE

Rotary AIDS project marks 20th anniversary with focus on prevention for ...  -  ‎Oct 21, 2009‎
A single dose of nevirapine administered to mothers could prevent 350000 infant infections each year. “Nevirapine is a wonder drug,� Casey said. ... Los Altos Town Crier

Fighting HIV, a Community at a Time  -  ‎Oct 26, 2009‎
In July, researchers conducting a large randomized trial in Malawi reported that giving the antiretroviral drug nevirapine to breast-feeding infants of ... New York Times

FDA Approves Labeling Update for REYATAZ® (atazanavir sulfate) Capsules to ...  -  ‎Nov 5, 2009‎
Coadministration with the following is not recommended: nevirapine; other protease inhibitors, fluticasone propionate or voriconazole when REYATAZ is given ... WELT ONLINE

Postexposure Prophylaxis for HIV Infection  -  ‎Oct 28, 2009‎
Nevirapine is not recommended for use in regimens for postexposure prophylaxis, given its associated risks of toxicity, including fulminant hepatitis and ... New England Journal of Medicine (subscription)

ART offer at antenatal clinics doubles uptake in Lusaka  -  ‎Nov 10, 2009‎
...countries are receiving antiretroviral treatment, a third of whom get single-dose nevirapine, the least effective form of preventive treatment. ... Aidsmap

Uganda: Baryamureeba's Dream for Makerere  -  ‎Oct 28, 2009‎
It is also an active centre for research; its scientists were part of the team that discovered Nevirapine, a drug used to prevent mother-to-child ... AllAfrica.com

Maternal HIV-1 treatment protects against transmission to newborns  -  ‎Oct 20, 2009‎
The authors had reported in 2008 that daily use of either nevirapine or nevirapine and zidovudine from birth up to the age of 14 weeks in breastfeeding ... innovations report

Business Update: Children's Cottage moves, Kristen's Marche changes ...  -  ‎Oct 31, 2009‎
Boehringer Ingelheim Pharmaceuticals, Inc. has begun the Viramune (nevirapine) tablets/oral suspension Co-Pay Savings Program, a special program that will ... Ridgefield Press

Boehringer Ingelheim continues providing non assert declarations to ...  -  ‎Oct 20, 2009‎
The company has further waived the provision of a nominal royalty fee under the access policy so the partnering companies can supply the nevirapine ... News-Medical.net

DA rejects green paper on national planning  -  ‎Nov 10, 2009‎
Antiretroviral Drugs: In January 2000, the DA defied national government policy to implement the country's first Nevirapine programme in Khayelitsha, ... Politicsweb

Aseguran que 14 mil contraen virus de sida cada 24 horas en el mundo  -  ‎Oct 31, 2009‎
Se inició en en el país el 15 de Mayo del 20000, con una donación de tres años de Nevirapine del gobierno de La Rioja, España. Actualmente opera en en 130 ... El Nacional (República Dominicana)

Pesquisa nos EUA quer examinar e tratar comunidades inteiras contra o HIV  -  ‎Oct 30, 2009‎
Em julho, pesquisadores conduzindo um grande experimento aleatório no Maláui relataram que administrar o remédio anti-retroviral nevirapine a bebês ... G1.com.br

Stevens-johnson syndrome  -  ‎Oct 23, 2009‎
...barbiturates, sulfonamides, phenytoin, azithromycin, modafinil[3], lamotrigine, nevirapine, ibuprofen[4], ethosuximide, carbamazepine)a tiez NSAID radu. ... Zdravie.sk

Comment les médicaments antirétroviraux ont transformé la vie des enfants ...  -  ‎Nov 4, 2009‎
Les ARV que nous disposons c'est essentiellement l'AZT, la stavudine, efavirenz, le nevirapine, lamivudine, le Viracept®. ... papamamanbebe.net

中国医è?¯äº§ä¸šç«žäº‰åŠ›æž„å»ºä¸Žå?¯æŒ?ç»­å?‘展  -  ‎Nov 2, 2009‎
...其中有国产的包括:阿扎那韦 (Atazanavir),2014å¹´1月美国专利到期;奈韦拉平(Nevirapine),2011å¹´11月美国专利到期;å?Œæ ·å°†äºŽ2011å¹´11月美国专利到期的还有HIV ... 中国生物技术信息网

Use of AIDS Medicine Might Be Altered to Avert Drug Resistance  -  Feb 26, 2005
24 -- AIDS experts have reached the conclusion that nevirapine, ... The current nevirapine regimen -- which requires an infant to also get a dose of the ... Washington Post

Study Finds Drug Resistance Fades Quickly in Key AIDS Drug  -  Jan 10, 2007
One of the main weapons to prevent mother-to-child transmission of the AIDS virus during birth is the drug nevirapine. But when nevirapine is used alone ... Voice of America

Africa: Africa: New Nevirapine Research Challenges Earlier Findings  -  Feb 10, 2006
Johannesburg — New research from the US Centres for Disease Control and Prevention (CDC) shows that the anti-AIDS drug, nevirapine, can prevent the spread ... AllAfrica.com

Whistleblower says US bungled AIDS study  -  Jan 4, 2005
Fishbein did not draw any conclusions about whether nevirapine is a safe or ... Nevirapine is an antiretroviral drug used since the 1990s to treat adult ... msnbc.com

Review backs efficacy of AIDS regimen.  -  Apr 8, 2005
..."Nevirapine is really the cornerstone of efforts to reduce transmission of ... Because nevirapine is seen as both effective and affordable -- treatment for ... Free with registration - Boston Globe - AccessMyLibrary.com

Strides gets USFDA approval for Nevirapine  -  Aug 14, 2006
Strides Arcolab has received tentative approval from the United States Food and Drug Administration for Nevirapine Tablets 200mg. ... Business Standard

Efavirenz Superior to Nevirapine for Treating HIV in Coinfected...  -  Aug 4, 2008
By Ed Susman. MEXICO CITY -- August 4, 2008 -- An efavirenz-based regimen appears more successful than a nevirapine-based regimen in the treatment of human ... DG News

Study: HIV drug can persist in mothers' milk_English_Xinhua  -  Aug 6, 2008
The researchers found that the drug, nevirapine, stays in the blood and breast milk ... "In the short term, nevirapine is better than nothing," said David ... 新�网

When a Pill Is Not Enough  -  Aug 6, 2006
Nevirapine is widely available, yet more than 70000 babies a year are born there with ... Mothers sometimes reject nevirapine. People decline AIDS tests. ... New York Times

Article: Cheap HIV drug said to be safe for pregnant women - Internati...  -  Jan 12, 2007
Women can take the anti-AIDS drug nevirapine to protect their unborn ... ''There was real concern that single-dose nevirapine was blowing the use of that ... Pay-Per-View - International Herald Tribune - HighBeam Research

CORRECTED: HIV drugs make breast-feeding safer  -  Feb 5, 2008
Babies of HIV-infected women who were given the drug nevirapine while they breast-fed were ... Nevirapine is already widely used to protect babies at birth. ... Reuters India

WHO relists Ranbaxy's anti-retroviral Nevirapine  -  Oct 1, 2005
THE World Health Organisation (WHO) has relisted Ranbaxy Laboratories Ltd's anti-retroviral (ARV) drug, Nevirapine tablets 200 mg, on its pre-qualification ... Hindu Business Line

Africa: "Tail" Regimen For PMTCT the Way to Go  -  Dec 6, 2007
Single dose nevirapine given to the mother and infant are an essential part ... AZT will soon be added to the current single dose nevirapine regimen as part ... AllAfrica.com

FDA Approves Generic AIDs Drug Combo  -  Jan 25, 2005
...a generic version of the Nevirapine drug made by Boehringer Ingelheim GmbH of Germany. The two drugmakers earlier licensed Aspen to produce the drugs. ... FOXNews

Rift Over AIDS Treatment Lingers in South Africa  -  Mar 9, 2008
His mother, not shown here, was given only nevirapine before his birth in 2006. ... The evidence that two drugs together — AZT plus nevirapine — work better ... New York Times

… : New Zambian Research Contradicts Ugandan Study On Nevirapine  -  Sep 13, 2006
Nairobi — Recent Zambian research into the antiretroviral (ARV) drug, nevirapine, has found that it does not compromise the long-term health of women, ... AllAfrica.com

Anti-AIDS drug for newborns gets boost  -  Apr 10, 2005
New research suggests that nevirapine works best when given with a drug called ... Combivir dramatically reduces the likelihood that single-dose nevirapine ... USA Today

US Opens the Door to Chinese Pills  -  Oct 9, 2007
Huahai currently sells nevirapine to the Chinese government for around $3.50 ... Whether or not Huahai meets its ambitious goals, the nevirapine approval is ... Wall Street Journal

Longer drug therapy helps babies ward off AIDS  -  Jun 4, 2008
Nevirapine is sold under the brand name Viramune by privately held Boehringer ... Giving nevirapine plus AZT for 14 weeks offered no additional benefit, ... Reuters UK

Africa: Nevirapine is 'Safe'  -  Mar 14, 2006
Nairobi — LATEST STUDIES ON THE controversy-ridden Nevirapine drug show that the resistance to other HIV/Aids medicines that it was feared to occasion poses ... AllAfrica.com

In Botswana, a success in reducing HIV in newborns  -  Aug 28, 2007
With a single dose of nevirapine, that risk is cut roughly in half. In the cases where a mother passes HIV to her child, roughly two-thirds occur during ... New York Times

Relooking at single-dose nevirapine strategy, to cut drug resistance  -  Jun 5, 2008
Eight years after starting the programme of giving single-dose nevirapine to both mother and infant to cut the mother-to-child transmission (vertical ... Hindu

… and plasma pharmacokinetics of nevirapine in human immunodeficiency...  -  Jan 31, 2005
Lisa M. Almond PhD 1 , Damitha Edirisinghe MRCP 1 , Mark Dalton RGN 1 , Alec Bonington FRCP 1 , David J. Back PhD 1 and Saye H. Khoo FRCP 1 ... Nature.com

Drug to protect babies from HIV creates resistance  -  Apr 29, 2006
Previous studies had suggested that any nevirapine-resistant HIV arising as ... This means that if a woman takes nevirapine again, whether to treat her own ... New Scientist

Boehringer Ingelheim drug in combination halves HIV resistance risk -...  -  Nov 7, 2007
LONDON (Thomson Financial) - Boehringer Ingelheim's HIV drug nevirapine taken ... Up to now, a single dose of the drug nevirapine during labour reduced the ... Forbes

Article: Use of AIDS Medicine Might Be Altered to Avert Drug Resistanc...  -  Feb 25, 2005
AIDS experts have reached the conclusion that nevirapine, the workhorse drug that has prevented tens of thousands of cas... Pay-Per-View - Washington Post - HighBeam Research

Zimbabwe: Nevirapine Resistance Poses No Long-Term Risk  -  Mar 9, 2006
This means women who take a single dose of the drug to prevent transmission of HIV to their babies can still use Nevirapine successfully in subsequent ... AllAfrica.com

US OKs pediatric AIDS pill for global relief plan  -  Aug 14, 2007
The FDA also said it gave tentative approval to generic nevirapine tablets made by Hetero Drugs Ltd of India, which will also be available for the program. ... Reuters India

AIDS Panel Gets Money From Agency in Probe  -  Mar 16, 2005
IOM's review of NIH's study in Uganda of the AIDS drug nevirapine (search) has international implications. The study was relied on by the Bush ... FOXNews

Probe into drugs in South Africa  -  Aug 12, 2008
Certain types of Nevirapine, used by HIV-positive pregnant women, and Adco-Zidovudine (AZT) were recalled by Adcock Ingram over the weekend. ... BBC News

… Africa: Many HIV-Positive Pregnant Women Not Receiving Nevirapine ...  -  Aug 30, 2006
Johannesburg — Nearly a quarter of pregnant women who test positive for HIV in South Africa's Gauteng Province are not receiving nevirapine to prevent ... AllAfrica.com

South Africa: New PMTCT Protocol in Two Weeks  -  Nov 30, 2007
Yet only 74052 women received nevirapine prophylaxis ie less than half the ... Transmission rates using single-dose nevirapine are over 8% at best and ... AllAfrica.com

FDA Approves Two Drugs For AIDS Treatment - THINK MTV  -  Jun 22, 2005
Nevirapine is part of a class of drugs that keeps the AIDS virus from multiplying, and the drug is often used to prevent pregnant women from passing the HIV ... MTV.com

Antiretroviral drugs reduce HIV transmission via breast …  -  Feb 10, 2008
Public health officials have had great success blocking HIV transmission to newborns using the drugs AZT and nevirapine about the time of delivery, ... 新�网

Six-Month Delay In Onset Of Nevirapine-Based Antiretroviral Therapy …  -  Jan 15, 2007
Delaying the start of a nevirapine-based antiretroviral therapy by six months can prevent the development of drug resistance in HIV-positive women who took ... Medical News Today - Medical News Today (press release)

FDA OKs 3-Drug Combo Pill to Treat HIV  -  Jun 30, 2006
The twice-daily pills combine three drugs already widely used to treat human immunodeficiency virus: lamivudine, zidovudine and nevirapine. ... FOXNews

Packing error leads to huge Aids drug recall  -  Aug 9, 2008
Adcock Ingram retrieved nine boxes wrongly packed with Nevirapine but, to be safe, ... The problem arose when a worker packed Nevirapine into boxes for ... Independent Online

Nevirapine tablets.(International Pharmacopoeia)(Drug overview)  -  Jun 22, 2007
Draft proposal for the International Pharmocopoeia (April 2007). Please address any comments to Quality Assurance and Safety: Medicines, Medicines Policy ... Free with registration - WHO Drug Information - AccessMyLibrary.com

A drug is effective if better than a harmless control  -  Apr 28, 2005
Hence, our finding that single-dose nevirapine was significantly more effective in preventing HIV transmission than a very short course of zidovudine ... Nature.com

Extended-Dose Nevirapine May Reduce Risk of Mother-to-Infant HIV …  -  Jul 24, 2008
NEW YORK -- July 24, 2008 -- A regimen of extended-dose nevirapine could reduce the risk of infants contracting the HIV virus from their HIV-infected ... DG News

Uganda: Nevirapine Saved Reagan From Getting HIV  -  Nov 5, 2007
Kampala — EVERY time you say bye and continue to shoot a photo of him waving back, he says: "Bye bisuba," (meaning bye liar). Reagan Mujuni is only coming ... AllAfrica.com

ICAAC: Nevirapine's manufacturer examines rates of liver toxicity in...  -  Jan 9, 2006
The high rates of liver side-effects seen in a major study of nevirapine (Viramune) ... The study also found that exclusion of patients starting nevirapine ... Aidsmap

Nevirapine's effectiveness questioned after latest study  -  Jul 18, 2005
Nevirapine had a very long half-life, meaning that it took a long time for ... This meant that after giving the mother a dose of nevirapine during labour, ... The Mercury - The Mercury (subscription)

Breastfeeding made safer for infants of HIV-infected mothers  -  Feb 6, 2008
The researchers have claimed that an extended course of the antiretroviral drug, nevirapine (NVP), helps the breastfeeding babies of HIV-infected mothers to ... Indian Express

Mbeki Aids denial 'caused 300,000 deaths'  -  Mar 18, 2007
But South Africa restricted the availability of nevirapine to two pilot sites per province until December 2002. Under international pressure, South Africa ... guardian.co.uk

Calls to halt nevirapine  -  Sep 17, 2006
Calls are mounting for an end to the nevirapine programme for HIV-infected pregnant women, on the grounds that it is not working and should be integrated ... Mail & Guardian Online

Pediatric AIDS pill approved  -  Aug 13, 2007
The FDA also said it gave tentative approval to generic nevirapine tablets made by Hetero Drugs Ltd of India, which will also be available for the program. ... Reuters

ICAAC: Nevirapine still present in breastmilk two weeks after last...  -  Dec 20, 2005
Nevirapine (Viramune) can persist in the breastmilk of HIV-positive women treated with the drug to prevent mother-to-child transmission of HIV for up to 14 ... Aidsmap

India rejects Boehringer's AIDS drug patent plea  -  Jun 20, 2008
The company was trying to claim a patent on the syrup form of nevirapine, which is particularly important for children living with HIV who are unable to ... Times of India

Nevirapine (Systemic).(Drug overview)  -  Aug 1, 2006
Nevirapine ( ne-VYE-ra-peen) is used, with other medicines, in the treatment of the infection caused by the human immunodeficiency virus (HIV). ... Free with registration - USP DI-Volume II, Advice for the... - AccessMyLibrary.com

Government's Aids policy hinders treatment  -  Jan 25, 2007
There are more effective treatments available, but nevirapine is the treatment ... Using a single dose of nevirapine reduces the risk of transmission of the ... Independent Online

Misinformation on nevirapine safety puts developing country PMTCT …  -  May 1, 2005
In mid-December 2004, three "exclusive" Associated Press stories created widespread doubts about the use of nevirapine to prevent HW in many of ... $4.95 - Reproductive Health Matters - ECNext

SOUTH AFRICA: New improved PMTCT on the way  -  Jan 29, 2008
The infant receives a single dose of nevirapine after it is born, and then AZT for seven days. Earlier that week, the AIDS lobby group, Treatment Action ... Reuters AlertNet

Nevirapine (Systemic).  -  Feb 1, 2006
Nevirapine ( ne-VYE-ra-peen) is used, with other medicines, in the treatment of the infection caused by the human immunodeficiency virus (HIV). ... Free with registration - USP DI-Volume II, Advice for the... - AccessMyLibrary.com

Proceed with caution  -  Jun 20, 2008
Nevirapine, after all, is one of the first-line drugs used in India. Realising the implications, NACO has taken the first step by entrusting the Pune-based ... The Hindu

Single-dose nevirapine reduces HIV transmission in second delivery  -  Feb 25, 2005
HIV-positive mothers who have previously used single-dose nevirapine to prevent passing on HIV to their baby during delivery can use the same procedure to ... Aidsmap

Single-dose nevirapine not jeopardising mother's treatment, large …  -  Aug 17, 2006
Single-dose nevirapine used for prevention of mother-to-child transmission does not appear to be jeopardising the future treatment responses of mothers who ... Aidsmap

Safety of Nevirapine in Pregnancy  -  Apr 18, 2007
U. Natarajan 1 ; A. Pym 2 ; C. McDonald 3 ; P. Velisetty 4 ; SG Edwards 5 ; P. Hay 4 ; J. Welch 3 ; A. de Ruiter 1 ; GP Taylor 6 ; J. Anderson 2 ... Medscape

HHS Backs Protection For Special Consultant  -  Feb 2, 2005
...in research practices, including not obtaining proper informed consent, in NIH-sponsored studies of the drug nevirapine on African research subjects. ... Washington Post

Hepatotoxicity of Nevirapine in Virologically Suppressed Patients:...  -  Mar 16, 2005
Four randomized controlled trials with a pooled total of 410 patients were analysed in the meta-analysis [155 (38%) from the NEFA study, 101 (25%) from ... Medscape

Delay in use of nevirapine-based AIDS treatment can improve outcomes  -  Dec 1, 2007
Delaying the use of nevirapine-containing antiretroviral therapy (ART) for at least six months after labor may improve treatment outcomes among HIV-infected ... innovations report - Innovations-Report

South Africa: KZN Targets Doctor But Shoots Itself in the Foot  -  Feb 15, 2008
The Western Cape has been using AZT and nevirapine since 2004 and has cut the ... In KZN, which still uses nevirapine only, 22% of HIV positive mothers ... AllAfrica.com

Nevirapine safe for HIV positive women for PMTCT: Zambia and …  -  May 1, 2007
The World Health Organization has reaffirmed its support for the use of nevirapine following a new Zambian study into the effects of the drug on HIV ... Free with registration - Reproductive Health Matters - AccessMyLibrary.com

FDA Public Health Advisory for Nevirapine (Viramune), Liver Toxicity  -  Jan 24, 2005
This public health advisory informs health care providers and patients about recent safety-related changes to the nevirapine (Viramune) label (package ... i-newswire.com

… : Two studies show single-dose nevirapine prevents HIV transmission...  -  Feb 14, 2006
Women who have used single-dose nevirapine (Viramune) to prevent mother to child transmission (PMTCT) of HIV can use it with equal or greater success during ... Aidsmap

Aurobindo's Nevirapine included in WHO list  -  Dec 12, 2005
Aurobindo pharma's anti-retroviral drug Nevirapine tablets 200 mg has been included by World Health Organisation (WHO) in its pre-qualification list. ... Andhra Cafe

Striking a better bargain with HIV: new interventions needed to save ...  -  Jun 18, 2005
Two well-timed doses of a single drug, nevirapine--one dose going to the woman ... If nevirapine or related drugs are later used to treat these mothers as ... Free with registration - Science News - AccessMyLibrary.com

Article: Striking a better bargain with HIV: new interventions needed...  -  Jun 18, 2005
Africa who received single-dose nevirapine during labor. They also applied ... of women treated with single-dose nevirapine, Dr. Palmer and her associates . ... Pay-Per-View - Science News - HighBeam Research

Manto must reinstate KZN doctor, say DA  -  Feb 4, 2008
By this stage, 88percent of pregnant women with high CD4 counts were being given dual therapy (AZT plus Nevirapine), as opposed to the national policy of ... Dispatch Online

Failure to suppress viral load more likely with nevirapine than...  -  Nov 19, 2007
People with HIV and TB who start taking a nevirapine-based antiretroviral regimen (ART) while they are already taking standard tuberculosis (TB) treatment ... Aidsmap

… of IOM Panel Investigating Ugandan Nevirapine Study Receive NIH …  -  Mar 17, 2005
Two-thirds of the members of an... Institute of Medicine panel investigating an NIH-funded study of the antiretroviral drug nevirapine among pregnant women ... Medical News Today - Medical News Today (press release)

… Therapy Might Be Better Choice Than Nevirapine Alone To Prevent …  -  Feb 27, 2005
Antiretroviral drug combination therapy might be more effective in preventing mother-to-child HIV transmission and less likely to foster drug resistance ... Medical News Today - Medical News Today (press release)

Stevens-Johnson syndrome affects mother and son taking nevirapine  -  Jun 6, 2005
Two cases of the rare side-effect of nevirapine, Stevens-Johnson syndrome, involving a mother and her son, are reported in the June 10 th edition of AIDS. ... Aidsmap

South Africa: AIDS Session Gets a Miss From Minister  -  Aug 1, 2008
The minister questioned the safety of giving nevirapine to HIV-positive mothers who would later begin life-long antiretroviral therapy with a cocktail of ... AllAfrica.com

HIV/AIDS Therapy; Background provided on nevirapine  -  Feb 1, 2005
2005 FEB 1 - (NewsRx.com & NewsRx.net) -- In light of recent interest in the use of Viramune (nevirapine), Boehringer Ingelheim (BI) provided the following ... Pay-Per-View - Virus Weekly - Factiva, from Dow Jones

Learn about Nevirapine from Consumer Reports Health.  -  Jan 7, 2005
Nevirapine can cause severe, life-threatening liver damage, skin reactions, and allergic reactions. ... Full Alert. Nevirapine is used in combination with ... consumerreports.org

Liver risk linked to key AIDS drug  -  Jan 20, 2005
..."In spite of the potential for serious and life-threatening liver toxicity and skin rashes with nevirapine, there are multiple reasons why nevirapine ... $2.95 - Philadelphia Inquirer - NewsBank

South Africa: MPs Praise State's Dual Aids Plan  -  Mar 5, 2008
...is the introduction of dual therapy -- expectant mothers and infants will get AZT and nevirapine, a regimen more effective than standalone nevirapine. ... AllAfrica.com

Africa: Daily HIV/Aids Report  -  Jun 23, 2008
P. Kousalya, president of PWN, said, "We opposed the patent application on nevirapine hemihydrates (syrup) to ensure that it remains available for our ... AllAfrica.com

… Published In AIDS Show Viramune (nevirapine) Achieves Durable...  -  Feb 5, 2007
Long-term data from the Nevirapine/Efavirenz/Abacavir (NEFA) study demonstrate that patients who switched from a protease inhibitor-based regimen to a ... Medical News Today - Medical News Today (press release)

Boehringer To Reduce Price Of Antiretroviral Nevirapine In Low-,...  -  May 18, 2007
German pharmaceutical company Boehringer Ingelheim will reduce the price of its antiretroviral drug nevirapine, sold under the brand name Viramune, ... Medical News Today - Medical News Today (press release)

Exclusive: The Truth about Nevirapine  -  Sep 28, 2006
Last week, Dr. Edmund Tramont, Head of the National Institutes of Health (NIH) AIDS division, was outed by fellow NIH AIDS researcher Dr. Jonathan Fishbein, ... gnn.tv

Drug Resistance; Nevirapine resistance may be higher than previously ...  -  Jun 21, 2005
2005 JUN 21 - (NewsRx.com) -- The incidence of drug resistance associated with single-dose nevirapine, a drug used to prevent mother-to-child transmission ... Pay-Per-View - Life Science Weekly - Factiva, from Dow Jones

Low weight in women a risk factor for severe nevirapine liver...  -  Feb 17, 2005
The use of the nevirapine (Viramune) by women with a low body mass index (BMI) should be discouraged, according to a study published in the March 15 th ... Aidsmap

New options for HIV in pregnancy worldwide.(Obstetrics)  -  Apr 15, 2005
..."While people have been lauding [single-dose nevirapine] as a stunning ... The value of nevirapine monotherapy should be reassessed, Dr. McIntyre stressed, ... Free with registration - OB GYN News - AccessMyLibrary.com

Dr Pfaff is in the clear  -  Feb 21, 2008
At the time he was charged, official policy was that only a single drug, nevirapine, be administered. The department's decision to act against him met with ... Independent Online

… treat both themselves and new born with nevirapine, says Ugandan...  -  May 3, 2005
A total of 93 women were therefore provided with nevirapine for ... The remaining twelve women could not be provided with nevirapine because their test ... Aidsmap

Go ahead for dual HIV therapy for babies  -  Feb 14, 2008
About 60 percent of those who tested positive received nevirapine. “Various studies that have been conducted on the programme suggest that the transmission ... Citizen

Switch to nevirapine safe for treatment-experienced patients with...  -  Sep 6, 2007
Patients who experience increases in their CD4 cell counts after initiating potent antiretroviral therapy can safely change therapy to a regimen based on ... Aidsmap

Nevirapine lingers for two weeks after mums give birth  -  Jul 14, 2005
Dutch researchers this week confirmed the Thai findings reported last year, showing that women exposed to a single dose of nevirapine (Viramune)may still ... Aidsmap

Africa could stop babies getting HIV, experts say  -  Dec 4, 2005
I carried the nevirapine around with me in my handbag, ready to use it as soon as the time came," she said. Auwalu also learnt on the Internet that she ... Malaysia Star

HIV/AIDS Therapy; Background provided on nevirapine  -  Feb 5, 2005
2005 FEB 5 - (NewsRx.com & NewsRx.net) -- In light of recent interest in the use of Viramune (nevirapine), Boehringer Ingelheim (BI) provided the following ... Pay-Per-View - Obesity, Fitness & Wellness Week - Factiva, from Dow Jones

Strides Arcolab receives 1st NDA approval from USFDA  -  Mar 5, 2007
The company has already received tentative approval from FDA for Stavudine Capsules and Nevirapine Tablets. Four applications are under review with the US ... Business Standard

South Africa: Single Dose of Childbirth HIV Drug 'Can Be Fatal'  -  Nov 6, 2008
Cape Town — Taking just a single dose of nevirapine during childbirth can ... Nevirapine is widely used in SA and other developing countries to reduce the ... AllAfrica.com

Misinformation on nevirapine safety puts developing country PMTCT …  -  May 1, 2005
Misinformation on nevirapine safety puts developing country PMTCT programmes at risk.(ROUND UP: HIV/AIDS) ... find Reproductive Health Matters articles. Pay-Per-View - Reproductive Health Matters - HighBeam Research

Nevirapine Side Effects from Consumer Reports Health.  -  Jan 7, 2005
Nevirapine can cause severe, life-threatening liver damage, skin reactions, and allergic reactions. ... Full Alert. Nevirapine can cause severe, ... consumerreports.org

Should nevirapine be used to prevent mother-to-child transmission of...  -  Mar 1, 2005
Devrait-on faire appel a la nevirapine pour prevenir la transmission mere-enfant du VIH dans le cas des femmes dont le statut serologique est inconnu ? ... $4.95 - Bulletin of the World Health Organizatio... - ECNext

Timing variations don't affect nevirapine's impact on mother-to-child...  -  Oct 19, 2005
Variations in the timing of nevirapine (Viramune) dosing for both mother and infant don't ... Doctors have worried that if women take nevirapine too late, ... Aidsmap

Risk of resistance with nevirapine-containing HAART after pregnancy, ...  -  Feb 2, 2005
Women with a wide variety of HIV-1 subtypes, including B, B/G, F2 and G, who take nevirapine-containing HAART during the third trimester of their pregnancy ... Aidsmap

HIV drug researcher Mmiro dead  -  Mar 31, 2008
Mmiro was part of a team of researchers that conducted a study on Nevirapine, a drug that prevents mother-to-child transmission of the AIDS virus, in 1998. ... New Vision

Brand Names/Synonyms:
Nevirapine is also known by the following brand names and/or synonymsBIRG 0587; DRG-0116; HSDB 7164; NEV; NVP; Nevirapine; Nevirapine [Usan:Inn]; Viramune

Drug Category:
Nevirapine is categorized under the following by the FDA: Anti-HIV Agents; Nonnucleoside Reverse Transcriptase Inhibitors; ATC:J05AG01

Dosage Forms:
Tablets, Oral suspension

Absorption:
90% (absolute bioavailability 93 ± 9%)

Interactions:
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Chemical IUPAC Name:
1-cyclopropyl-5,11-dihydro-4-methyl-6H-dipyrido [3,2-b:2',3'-e][1,4] diazepin-6-one





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