Nicotrol NS

This page contains recent news articles, when available, and an overview of Nicotrol NS but does not offer medical advice. You should contact your physician with regard to any health issues or concerns.

Overview:

Nicotrol NS (when available)

Pharmacology and use:
Nicotine, the primary alkaloid in tobacco products binds stereo-selectively to nicotinic-cholinergic receptors on autonomic ganglia, the adrenal medulla, neuromuscular junctions and in the brain. Nicotine exerts two effects, a stimulant effect exerted at the locus ceruleus and a reward effect in the limbic system. Itranvenous administration of nicotine causes release of acetylcholine, norepinephrine, dopamine, serotonine, vasopressin, beta-endorphin and ACTH. Nicotine is a highly addictive substance. Nicotine also induces peripheral vasoconstriction, tachycardia and elevated blood pressure. Nicotine inhalers and patches are used to treat smoking withdrawl syndrome. Nicotine is classified as a stimulant of autonomic ganglia. For the relief of nicotine withdrawal symptoms and as an aid to smoking cessation

Mechanism Of Action:
Nicotine binds to the nicotinic acetylcholine receptor. Stimulation of nicotinic receptors leads to a variety of cholinergic and adrenergic effects; tachycardia or bradycardia mediated by either stimulation or interference with sympathetic or parasympathetic pathways, stimulation of receptors in the carotic and aortic bodies, release of epinephrine from the adrenal medulla, and stimulation of the chemoreceptor-trigger zone.

News Articles on Nicotine

Nicotrol NS.(Drug overview)  -  Jan 22, 2007
Nicotrol NS is used to relieve withdrawal symptoms in people who are attempting to give up smoking. It should be used as part of a comprehensive smoking ... Free with registration - PDR Family Guide to Prescription Drugs - AccessMyLibrary.com

Nicotine dependence  -  Nov 26, 2008
Nicotine nasal spray (Nicotrol NS). The nicotine in this product, sprayed directly into each nostril, is absorbed through your nasal membranes into your ... CNN

A MATTER OF TRUST: OXYTOCIN IN NASAL SPRAY.(News) | Article …  -  Jun 1, 2005
Nicotrol NS, a nicotine nasal spray, was approved last month by the Food and Drug Administration ... The Cincinnati Post (Cincinnati, OH) ... Pay-Per-View - Cincinnati Post - HighBeam Research

SignOnSanDiego.com > News > Health -- Up in smoke  -  Jun 28, 2005
WHAT IS IT: Sold under the brand name Nicotrol NS, the prescription nasal pump delivers nicotine to help curb withdrawal symptoms. ... San Diego Union - Tribune - San Diego Union Tribune

Article: Chew on this: Me and Obama? - Oakland Tribune | HighBeam …  -  Feb 18, 2008
NICOTROL NS, the first nicotine nasal spray to be introduced in the United ... Information NICOTROL(R) NS (nicotine nasal spray) is indicated as an aid ... ... Pay-Per-View - Oakland Tribune - HighBeam Research

Help From The Pharmacy  -  Mar 12, 2007
Products such as Nicotrol NS produce blood nicotine levels most similar to those produced by smoking, because you get a quick jolt of nicotine, ... Intelihealth.com

DRUGS used for SMOKING CESSATION THERAPY  -  Nov 19, 2007
Smoking cessation includes drug replacement therapies. Dental hygienists must be familiar with the drugs and be able to teach patients how to properly ... RDH

Case Grows to Cover Quitting  -  Apr 26, 2005
Nasal spray: Nicotrol NS, prescription required, $5 per day for average use (13 doses) or $15 per day for maximum usage (40 doses). ... Subscription - Wall Street Journal Online - Dow Jones & Company

Article: Nasal Spray Bottles.(NEW PRODUCTS) - Surgical Products | …  -  Feb 1, 2008
Article: Nicotine nasal spray (Nicotrol NS). (Medication ... Southern Medical Journal; April 1, 2002 ; 693 words ... ... Interest Potential for dependence ... Pay-Per-View - Surgical Products - HighBeam Research

Brand Names/Synonyms:
Nicotrol NS is also known by the following brand names and/or synonymsBlack Leaf; Black Leaf 40; Campbell's Nico-Soap; Commit; Destruxol Orchid Spray; Emo-Nik; Flux Maag; Fumetobac; Habitrol; L-Nicotine; Mach-Nic; Niagara P.A. Dust; Nic-Sal; Nico-Dust; Nico-Fume; Nicocide; Nicoderm; Nicoderm Cq; Nicorette; Nicorette Plus; Nicotin; Nicotina; Nicotine; Nicotine Alkaloid; Nicotine Polacrilex; Nicotrol; Nicotrol Inhaler; Nicotrol Ns; Nikotin; Nikotyna; Ortho N-4 Dust; Ortho N-5 Dust; Prostep; Tendust; Tetrahydronicotyrine, Dl-; Xl All Insecticide

Drug Category:
Nicotrol NS is categorized under the following by the FDA: Anti-craving Agents; Central Nervous System Agents; Autonomic drugs; Nicotinic Agonists; ATC:N07BA01

Dosage Forms:
Gum, Inhaler, Patches

Absorption:
Absorption of nicotine through the buccal mucosa is relatively slow and the high and rapid rise followed by the decline in nicotine arterial plasma concentrations seen with cigarette smoking are not achieved with the inhaler. About 10% of absorbed nicotine is excreted unchanged in urine.

Interactions:
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Chemical IUPAC Name:
3-(1-methylpyrrolidin-2-yl)pyridine

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