Olsalazine

This page contains recent news articles, when available, and an overview of Olsalazine but does not offer medical advice. You should contact your physician with regard to any health issues or concerns.


Overview:

Olsalazine
(when available)

Pharmacology and use:
Mirtazapine, an antidepressant of the piperazinoazepine class, is a tetracyclic compound with an anxiolytic effect. Mirtazapine has fewer ADRs than tricyclic antidepressants and is better tolerated. Selective blockade of specific serotonin receptors by mirtazapine likey minimizes side effects typical of other antidepressants. For the treatment of major depressive disorder

Mechanism Of Action:
Mirtazapine acts as an antagonist at central pre-synaptic alpha(2)-receptors, inhibiting negative feedback to the presynaptic nerve and causing an increase in NE release. Blockade of heteroreceptors, alpha(2)-receptors contained in serotenergic neurons, enhances the release of 5-HT, increasing the interactions between 5-HT and 5-HT1 receptors and contributing to the anxiolytic effects of mirtazapine. Mirtazapine also acts as a weak antagonist at 5-HT1 receptors and as a potent antagonist at 5-HT2 (particularly subtypes 2A and 2C) and 5-HT3 receptors. Blockade of these receptors may explain the lower incidence of adverse effects such as anxiety, insomnia, and nausea. Mirtazapine also exhibits significant antagonism at H1-receptors, resulting in sedation. Mirtazapine has no effects on the reuptake of either NE or 5-HT and has only minimal activity at dopaminergic and muscarinic receptors.

News Articles on Mirtazapine

Shire Presents Results of Five Lialda(R) (mesalamine) Analyses at ACG 2009 ...  -  ‎Oct 26, 2009‎
...balsalazide [combined results from generic balsalazide disodium and Colazal® (balsalazide disodium)], and Dipentum® (olsalazine sodium) (500mg). ... Reuters

Olsalazine (Oral).  -  Feb 1, 2006
Olsalazine (ole-SAL-a-zeen) is used in patients who have had ulcerative colitis to prevent the condition from occurring again. It works inside the bowel by ... Free with registration - USP DI-Volume II, Advice for the... - AccessMyLibrary.com

Ulcerative colitis  -  Oct 4, 2005
Mesalamine (Asacol, Rowasa) and olsalazine (Dipentum). These medications tend to have ... Olsalazine may cause or worsen existing diarrhea in some people. ... cnn.com

Aminosalicylates for inflammatory bowel disease  -  Oct 9, 2008
Mesalamine, olsalazine, and balsalazide do not contain sulfa, ... Sulfasalazine, mesalamine, balsalazide, and olsalazine can be used to maintain remission ... WebMD

Practice Guidelines  -  Feb 1, 2005
The following drug regimens were all found to be effective in maintaining remission in distal disease: sulfasalazine, 2 g per day; olsalazine, 1 g per day, ... AAFP News Now

How to take Mesalamine from Consumer Reports Health.  -  Jan 10, 2006
...tell your doctor and pharmacist if you are allergic to mesalamine, balsalazide (Colazal); olsalazine (Dipentum); salicylate pain relievers such as aspirin, ... consumerreports.org

Sulfasalazine, dapsone: good alternative options, for treatment of...  -  Jan 1, 2007
Unlike sulfasalazine, olsalazine has no sulfa moiety, and therefore, agranulocytosis is not a risk; it can be used in sulfa-allergic patients or patients ... $4.95 - Dermatology Times - ECNext

Crohn's Disease Medications - Crohn's Disease Health Information - NY...  -  Feb 20, 2008
...including mesalamine (Asacol, Pentasa), olsalazine (Dipentum), and balsalazide (Colazal). These drugs, like sulfazine, are available as pills. ... New York Times

A 36 year-old male with ulcerative colitis and renal failure <!-...  -  Nov 11, 2007
Dipentum (olsalazine) is a dimerized form of 5-ASA which, similar to sulfasalazine, requires bacterial cleavage in the colon for activation. ... Nature.com

Strong 2004 performance: Positive outlook for 2005. | Article from PR...  -  Mar 2, 2005
US prescription volumes increased 2% over the same period, in line with the oral mesalamine/olsalazine market growth. The difference between sales growth ... Pay-Per-View - PR Newswire UK Disclose - HighBeam Research

Giaconda gets European patent for drug  -  Dec 28, 2006
The patent provides protection in 19 European countries for the Sydney company's Ibaconda drug - combination of olsalazine and colchicine - for the ... Sydney Morning Herald

Combined oral and topical mesalazine treatment for extensive ulcerativ...  -  Nov 30, 2005
The initial therapy given for ulcerative colitis is usually 5-aminosalicylates (5-ASAs), such as sulfasalazine, mesalazine, or olsalazine. ... Nature.com

Inflammatory bowel disease: "new treatments won't set market alight".  -  Mar 12, 2007
...mesalazine, olsalazine and sulfasalazine), an existing class of medication, Datamonitor predicts less success for biologics in this indication. ... Free with registration - Pharma Marketletter - AccessMyLibrary.com

Hollis-Eden Pharmaceuticals Commences Phase I/II Clinical Trial In …  -  Feb 11, 2008
Current first-line anti-inflammatory drugs for the treatment of UC are topical 5-ASA compounds such as sulfasalazine-, olsalazine- and mesalimine-based ... Medical News Today - Medical News Today (press release)

Clinical: Ulcerative colitis and Crohn's disease.  -  May 26, 2006
Aminosalicylates are the most widely used medications in IBD, and include mesalazine (5-aminosalicylic acid or 5-ASAs) sulfasalazine, olsalazine, ... Free with registration - GP - AccessMyLibrary.com

Hollis-Eden Pharmaceuticals Commences Phase I/II Clinical Trial in …  -  Feb 7, 2008
Current first-line anti-inflammatory drugs for the treatment of UC are topical 5-ASA compounds such as sulfasalazine-, olsalazine- and mesalimine-based ... Lifescience-online

Dan Shen.  -  Feb 1, 2007
Medicine used for pain, swelling, and certain stomach or intestinal problems (examples: aspirin, mesalamine (Asacol(R), Pentasa(R)), olsalazine ... Free with registration - AltCareDex Alternative Medicines - AccessMyLibrary.com

Inflammatory Bowel Disease  -  Feb 1, 2005
Some of these medicines are sulfasalazine (brand name: Azulfidine), olsalazine (brand name: Dipentum), and mesalamine (brand names: Asacol, Pentasa, Rowasa) ... AAFP News Now

Mesalamine (Oral).(Drug overview)  -  May 1, 2006
Tell your doctor if you have ever had any unusual or allergic reaction to mesalamine, olsalazine, sulfasalazine, or any salicylates (for example, aspirin). ... Free with registration - USP DI-Volume II, Advice for the... - AccessMyLibrary.com

Ulcerative Colitis  -  Aug 27, 2007
Some medicines in this group include sulfasalazine (Azulfidine), mesalamine (Asacol, Pentasa, Rowasa) and olsalazine (Dipentum). These medicines clear up ... HealthCentral.com

How to recognize and treat IBD: recognizing, diagnosing, and managing...  -  Dec 1, 2005
Oral medications include mesalamine (Asacol, Pentasa) and olsalazine (Dipentum). For patients whose disease is limited to the rectum or lower part of the ... Free with registration - Patient Care for the Nurse Practitioner - AccessMyLibrary.com

Mesalamine (Oral).  -  Aug 1, 2006
Tell your doctor if you have ever had any unusual or allergic reaction to mesalamine, olsalazine, sulfasalazine, or any salicylates (for example, aspirin). ... Free with registration - USP DI-Volume II, Advice for the... - AccessMyLibrary.com

Pharmacy Update - Ulcerative colitis: an overview.(Medical condition ...  -  May 5, 2007
Eighty per cent of patients intolerant of sulphasalazine can tolerate mesalazine, olsalazine and balsalazide. Rarely, interstitial nephritis or the ... Free with registration - Chemist & Druggist - AccessMyLibrary.com

GI Agents: Part II.(Drugs, Pregnancy, And Lactation)  -  Mar 1, 2006
Two other agents in this class, balsalazide (Colazal) and olsalazine (Dipentum), are broken down in the colon to 5-ASA. Both of these agents appear to be ... Free with registration - Family Practice News - AccessMyLibrary.com

Pharmacokinetics | Practice | Nursing Times  -  Nov 19, 2007
Other formulations, such as olsalazine and balsalazide, rely on bacterial breakdown of an inactive molecule to form mesalazine in the lower bowel. ... Nursing Times

Federal Register 2007 - 72 FR 30386 Draft Guidances for Industry …  -  May 31, 2007
Nabumetone Nateglinide Nelfinavir Mesylate Nevirapine O Olanzapine Olmesartan Medoxomil Olsalazine Sodium Omeprazole (multiple dosage forms) Omeprazole ... Pay-Per-View - Federal Register 2007 - Loislaw

Oregon Regulations - 850-060-0226 Naturopathic Formulary by …  -  Feb 1, 2006
...(cc) Indomethacin; (dd) Ketorolac; (ee) Sulindac; (ff) Tolmetin; (ii) Amino Aspirins; (iii) Celecoxib; (iv) Mesalamine; (v) Olsalazine; (vi) Oxaprozin; ... Pay-Per-View - Oregon Regulations - Loislaw

Colitis ulcerosa  -  Oct 4, 2005
Voorbeelden zijn mesalazine, olsalazine en sulfasalazine. Bijnierschorshormonen, ofwel corticosteroïden, remmen de ontstekingen. Hierdoor zullen buikpijn ... kiesbeter.nl

Oregon Regulations - 850-060-0225 Naturopathic Formulary …  -  Feb 1, 2006
...(261) Olsalazine; (262) Omeprazole; (263) Opium; (264) Over the Counter (OTC) (265) Oxacillin; (266) Oxamniquine; (267) Oxaprozin; (268) Oxtriphylline; ... Pay-Per-View - Oregon Regulations - Loislaw

Lo stato dell'arte sulla colite ulcerosa  -  Nov 23, 2006
...composti di acido 5 aminosalicilico legati a molecole che ne permettono la liberazione a livello del colon (balsalazide, olsalazine, sulfasalazina). ... Pillole.org

Brand Names/Synonyms:
Olsalazine is also known by the following brand names and/or synonymsCHEMBANK1791; Mepirzepine; Mirtazapina [Inn-Spanish]; Mirtazapine; Mirtazapine [Usan:Ban:Inn]; Mirtazapinum [Inn-Latin]; Mirtazepine; ORG 3770; Olsalazine; Org-3770; Remeron; Remeron Soltab; Soltabt

Drug Category:
Olsalazine is categorized under the following by the FDA: Adrenergic alpha-Antagonists; Antidepressive Agents, Tricyclic; Histamine H1 Antagonists; ATC:N06AX11

Dosage Forms:
TABLET; TABLET (ORALLY DISINTEGRATING)

Absorption:
Rapid and complete, but, due to first-pass metabolism, absolute bioavailability is 50%.

Interactions:
[an error occurred while processing this directive]



Chemical IUPAC Name:
1,2,3,4,10,14b-hexahydro-2-methylpyrazino[2,1-a]pyrido[2,3-c][2]benzazepine





Health Home | Conditions | Cancer | Medications | Surgery | Vaccines


The Cancer News Network


Disclaimer:

Contact a physician with regard to health concerns. Email requests for further health information will be discarded.

The materials contained on this Web site are for informational purposes only and do not constitute health or medical advice. Use of information on this site does not create or constitute any kind of agreement or contract between you and the owners or users of this site, the owners of the servers upon which it is housed, or anyone else who is in any way connected with this site.

Many links on cancernewsnetwork.org lead to other sites. cancernewsnetwork.org does not sponsor, endorse or otherwise approve of the materials appearing in such sites. Nor is CancerNewsNetwork.org responsible for dead or misdirected links.

IF YOU NEED A LINK OR TEXT REMOVED FROM THIS PAGE PLEASE CONTACT cancernewsnetwork (at) live.com.
We will do our best to accommodate your request.



COPYRIGHT 2009 CANCERNEWSNETWORK | Privacy