Orlistat

This page contains recent news articles, when available, and an overview of Orlistat but does not offer medical advice. You should contact your physician with regard to any health issues or concerns.


Overview:

Orlistat
(when available)

Pharmacology and use:
Orlistat is a lipase inhibitor used for obesity management that acts by inhibiting the absorption of dietary fats. For the treatment of Obesity including management of weight loss and weight maintenance

Mechanism Of Action:
Orlistat is a reversible inhibitor of lipases. It exerts its therapeutic activity in the lumen of the stomach and small intestine by forming a covalent bond with the active serine residue site of gastric and pancreatic lipases. The inactivated enzymes are thus unavailable to hydrolyze dietary fat in the form of triglycerides into absorbable free fatty acids and monoglycerides. As undigested triglycerides are not absorbed, the resulting caloric deficit may have a positive effect on weight control.

News Articles on Orlistat

美国FDAå?‘布奥利å?¸ä»–早期安全评估结果  -  05 Jan 2010
1999å¹´FDA批准Xenical(Orlista 120mg)作为一ç§?é…?å?ˆä½Žå?¡è·¯é‡Œé£Ÿè°±ä½¿ç”¨çš„å‡?肥处方è?¯ï¼Œå¹¶å?¯ä»¥é™?低å‡?è‚¥å?Žä½“é‡?å??弹的风险。2007å¹´Alli(Orlistat 60mg)也被批准为é…?å?ˆä½Ž ... 中国医药网

İlaç kavgasında hapı kim yutacak?  -  05 Jan 2010
Dr. Osman Müftüoğlu da, ilaçların yan ve olumsuz etkilerine karşı uyarıyor: “Orlistat, kilo kaybı için kullanılan, yağ emilimini azaltan bir ilaçtır. ... Aksiyon

Arena Pharmaceuticals Submits Application for New Weight Loss Drug Lorcaserin  -  ‎Dec 22, 2009‎
Xenical (orlistat) made by Roche prevents the absoprtion of fat in the intestine. Alli is a reduced strength version of orlistat and available ... eMaxHealth

Did you get one of these health products for Christmas? If so, do you have a ...  -  ‎Jan 1, 2010‎
Consumer Reports notes that the active ingredient in Alli and Xenical, called orlistat, has embarrassing side effects. Orlando Sentinel

Extreme Ways to Lose Weight Pills and drastic diets are still popular, despite ...  -  ‎Jan 1, 2010‎
Orlistat comes next, yet another prescription drug, which is now available in diluted concentration over the counter in many territories. ... Softpedia

Viagra rrp australia  -  ‎Dec 19, 2009‎
Orlistat is used in patients with 3 6 Viagra rrp australia with diabetes mellitus or following radical anti obesity drugs intracavernosal injections are. Australia.TO

Method Discovered to Make Leukemic Cells Vulnerable to Apoptosis  -  ‎Dec 22, 2009‎
Likewise, treatment with the fatty acid synthase/lipolysis inhibitor orlistat also sensitized leukemia cells to ABT-737. Etomoxir decreased the number of ... Genetic Engineering News (press release)

Piden llevar control médico para perder peso  -  ‎Jan 3, 2010‎
También utilizan el Orlistat, fármaco que disminuye hasta en un 30 por ciento la absorción de grasas pero los medicamentos que contienen estos activos ... Diario Digital Juárez

Alli, la pilule qui fait maigrir, est souvent mal utilisée  -  ‎Dec 21, 2009‎
L'Afssaps (Agence française de Sécurité sanitaire des Produits de Santé) vient de publier le bilan de l'utilisation de Alli (Orlistat à 60 mg). ... Futura Sciences

ALLI® : Indiqué pour l'obésité, pas pour les excès  -  ‎Jan 1, 2010‎
Le principe actif d'Alli®, l'orlistat, est un inhibiteur spécifique et d'action prolongée des lipases gastrointestinales qui limite l'absorption des ... santé log

Wijziging productinformatie alli (orlistat) 60 mg  -  ‎Dec 11, 2009‎
Patiënten met een nieraandoening moeten, voordat het gebruik van alli (orlistat) 60 mg capsules wordt gestart, een arts raadplegen. In zeldzame gevallen kan ... Medical facts

Cintura peligrosa (cont.)  -  ‎Dec 22, 2009‎
Hoy por hoy sólo hay dos medicamentos indicados para obesidad: uno que disminuye la absorción intestinal (Orlistat) y otro que aumenta la sensación de ... La Vanguardia

Alli - racionálnÄ› proti obezitÄ›  -  ‎Jan 1, 2010‎
Mezi léky používanými pro léÄ?bu obezity se nejÄ?astÄ›ji používají dvÄ› úÄ?inné látky: orlistat a sibutramin. Až donedávna vÅ¡ak byli obÄ› látky dostupné pouze v ... Pressweb (tisková zpráva)

Advarer mot nok en slankepille  -  ‎Dec 21, 2009‎
Medisinen inneholder virkestoffet orlistat, som skal hindre fettopptak i tarmen. Det var de amerikanske legemiddelmyndigheter som i august først gikk ut med ... Kvinner og klær

백혈병 치료 새 방법 개발 가능  -  ‎Dec 27, 2009‎
...연구진ì?€ 지방ì?˜ í?¡ìˆ˜ë¥¼ 줄여 ì‚´ì?„ 빼게 해주는 '올리스탯(orlistat)'ë?„ 백혈병 세í?¬ë¥¼ 민ê°?화시켜서 ABT-737ì?˜ 항암효과를 ì¦?대시켰다고 ë°?혔다. ... 헬스코리아뉴스

El Peligro de las Dietas de Emergencia  -  ‎Dec 18, 2009‎
...hay sólo dos fármacos con evidencia científica y que cuentan con aprobación internacional para el tratamiento de la obesidad: orlistat y sibutramina. ... Chile.com

Meer bijwerkingen Alli afslankpil bekend  -  ‎Dec 13, 2009‎
Alli bevat de helft van de werkzame stof orlistat (60 mg) en is vrij verkrijgbaar. Alli kan als ondersteuning van een dieet worden gebruikt door mensen met ... Blog.nl (Blog)

Alli : un bilan sanitaire plutôt positif après sept mois de commercialisation  -  ‎Dec 22, 2009‎
Elle contient une molécule (orlistat) qui était disponible jusque là sur ordonnance, dans un dosage deux fois supérieur (120 mg contre 60mg pour Alli). Toute la diététique !

ยาลด ความอ้วน  -  ‎Dec 20, 2009‎
1.2สารยับยั้งà¸?ารทำงานของเอนไซม์ ไลเปส เช่น Orlistat จะออà¸?ฤทธิ์ยับยั้งà¸?ารทำงานของเอนไซม์ไลเปส ซึ่งเป็นเอน ไซม์ที่ย่อยไขมันในรูปที่ร่างà¸?ายนำไปใช้ได้ ... สยามธุรกิจ

Das Dilemma mit den leckeren Weihnachtskeksen Genuss ohne Reue Das Dilemma mit ...  -  ‎Dec 16, 2009‎
Genieß einfach die tolle Zeit und die heimeligen Momente – Wir wünschen viel Erfolg und frohe Weihnachten! alli, Orlistat 60 mg. ... Krone.at

Abnehmen ist Neujahrsvorsatz Nummer eins: Mit dem Drei-Säulen-Prinzip gesund ...  -  ‎Dec 16, 2009‎
Dort blockiert der Wirkstoff Orlistat etwa 25 Prozent des aufgenommenen Fetts, so dass dieses gar nicht erst in den Stoffwechsel gelangen kann, ... food-monitor (Pressemitteilung)

Liraglutide treatment led to greater reduction in body weight than placebo ...  -  ‎Oct 26, 2009‎
Those assigned to placebo lost a mean 2.8 kg and those assigned to orlistat lost a mean 4.1 kg. In comparison, participants assigned to liraglutide lost a ... Endocrine Today

Get effective Obesity Treatment through Xenical Weight loss pills  -  ‎Nov 11, 2009‎
Xenical, active ingredient orlistat, is a highly effective weight loss pill used by men and women. A product of Roche laboratories, it can help you to ... Best Syndication

On the Pulse - 13th November 2009  -  ‎Nov 13, 2009‎
By comparison, those substituting liraglutide with placebo lost only 2.8 kg, and those receiving orlistat, 4.1 kg. An accompanying Comment observes that the ... OnMedica

Looking for an ally? Take a pill  -  ‎Oct 29, 2009‎
One such weight loss drug garnering interest is Orlistat (also known as tetrahydrolipstatin). It's already being marketed in the Philippines under the trade ... BusinessWorld Online

Fears emerge over weight-loss drug's links with kidney damage  -  ‎Nov 2, 2009‎
Alli, also known as Orlistat, became the first weight-loss drug approved by the Food and Drugs Administration in the US to be sold over the counter in 2007. ... Irish Times

How a new drug helps one lose weight the healthy way  -  ‎Nov 9, 2009‎
That's where Orlistat (Alli) steps in. “Alli helps boost weight loss. For every two pounds you lose, Alli helps you lose one pound more. ... Inquirer.net

Weight loss ally supports healthy lifestyle options  -  ‎Nov 9, 2009‎
Orlistat (alli) t helps boost weight loss. So for every two pounds you lose on your own, the formulation helps you lose one pound more. ... Malaya

New weight loss drugs on the horizon!  -  ‎Nov 7, 2009‎
In addition to the two medications currently available (Sibutramine (Meridia) and Orlistat (Xenical)), there are at least three new medications that are in ... Drumheller Mail

Effects of liraglutide in the treatment of obesity: a randomised, double-blind ...  -  ‎Oct 30, 2009‎
In the trial, 564 patients were randomized to one of six groups: orlistat (120 mg, 3 times daily), placebo, and liraglutide 1.2 mg, 1.8 mg, 2.4 mg, ... Gerson Lehrman Group

LC: Speech bySFH on Pharmacy and Poisons Ordinance  -  ‎Oct 22, 2009‎
In addition, the Pharmacy and Poisons Board proposes to relax the control of "orlistat when contained in pharmaceutical products the recommended daily dose ... 7thSpace Interactive (press release)

New Prescription Diet Pills Coming Soon  -  ‎Oct 23, 2009‎
Orlistat is sold in a lower dose over-the-counter, like Alli. The Food and Drug Administration is reviewing safety information regarding reports of ... That's Fit

Victoza yields substantial weight loss in diabetic patients, study finds  -  ‎Oct 26, 2009‎
...(liraglutide) in a 1.2 mg, 1.8mg, 2.4 mg or 3 mg dose, GlaxoSmithKline's weight-loss drug Alli (orlistat) in a 120 mg dose or placebo three times a day. ... Drug Store News (blog)

Too fat? Weigh up risks of gastric band  -  ‎Nov 11, 2009‎
For example, orlistat - which stops you absorbing fat - can cause gut problems like wind or leakage. An alternative, sibutramine, is an appetite-suppressant ... The Sun

Jeremy Laurance: A breakthrough – but the real answer lies in exercise and diet  -  ‎Oct 22, 2009‎
This could give it the edge over sibutramine, which raises blood pressure, and orlistat, which has unpleasant, although not unsafe, effects on the digestion ... Independent

New Diabetes Drug Helps Obese Adults With Weight Loss  -  ‎Oct 26, 2009‎
One group received the weight loss medication orlistat, found in the currently available medications Xenical and Alli. The control group received a placebo. ... eMaxHealth

Adherence to the Mediterranean Diet Moderates the Association of ...  -  ‎Oct 22, 2009‎
Harrison SA, Fecht W, Brunt EM, Neuschwander-Tetri BA: Orlistat for overweight subjects with nonalcoholic steatohepatitis: A randomized, prospective trial. ... Medscape

Nueva promesa en la batalla antiobesidad  -  ‎Oct 22, 2009‎
Según los resultados de un estudio preliminar, el fármaco podría ser más efectivo -en su dosis más alta- que el ya comercializado orlistat. ... elmundo.es

Übergewicht und Bluthochdruck: Unheiliges Duo  -  ‎Nov 12, 2009‎
Für Orlistat zeigte sich eine Gewichtsabnahme von im Mittel 3,7 kg, für Sibutramin von 3,4 kg. Bei der Reduzierung des Blutdruckes berichtet das IQWiG für ... MedizinAuskunft

Droga contra la diabetes que adelgaza  -  ‎Oct 23, 2009‎
Un portavoz de GlaxoSmithKline, que produce orlistat, dijo que la comparación era injusta pues las drogas fueron administradas en diferentes dosis y maneras ... BBC Mundo

FDA onderzoekt meldingen van leverschade door orlistat  -  ‎Oct 23, 2009‎
De Amerikaanse Food and Drug Administration (FDA) onderzoekt een mogelijk verband tussen het gebruik van het vermageringsmiddel orlistat en het optreden van ... Gezondheid.be

Bien trop tôt pour crier Victoza  -  ‎Oct 26, 2009‎
Comparé à l'orlistat (Xenical, Alli), ce dernier pourrait s'avérer un blockbuster sans précédent… avec un impact moyen de 9% sur le poids par rapport à la ... Bloob

Hilft Liraglutid Nichtdiabetikern beim Abnehmen?  -  ‎Nov 9, 2009‎
Verglichen wurde die Therapie mit Liraglutid in den Dosierungen 1,2 mg, 1,8 mg, 2,4 mg und 3,0 mg einmal täglich subkutan, mit Placebo und mit Orlistat in ... Ärzte Zeitung

Trois millions de nouveaux obèses en France  -  ‎Nov 13, 2009‎
Financée par Roche -qui commercialise le traitement de l'obésité Xenical* (orlistat)-, l'enquête est réalisée par TNS Healthcare Sofres. ... Mondesante.com

시오노기 항비만제 복합제 개발 추진  -  ‎Nov 9, 2009‎
...ì?¼ë³¸ 시오노기제약ì?€ 미국ì—?서 후기2ìƒ? ìž„ìƒ? 중ì?¸ 항비만제 'S-2367'(velneperit)ì—? 대해 체중ê°?소 효과를 높ì?´ê¸° 위해 GSKì?˜ 항비만제 '오를리스타트'(orlistat)와ì?˜ ... 메디파나뉴스

Un medicament antidiabetic ajută obezii să slăbească  -  ‎Oct 26, 2009‎
...al doilea grup a primit Orlistat, un medicament împotriva obezităţii comercializat sub numele de Xenical, iar al treilea grup a primit un placebo. ... Anima News

Thuốc mập, thuốc ốm  -  ‎Nov 12, 2009‎
...thá»±c phẩm Mỹ chấp thuận dùng trong Ä‘iá»?u trị và ở ta cÅ©ng thưá»?ng hay chỉ định dùng cho ngưá»?i cần làm ốm là orlistat (Xenical) và sibutramin (Reductil). ... Người Lao Động

ЛекарÑ?тво за диабет бори и затлъÑ?Ñ‚Ñ?ването  -  ‎Oct 22, 2009‎
Първата получавала дневно liraglutide на четири различни дози; втората - orlistat; на третата учените давали безвредна Ñ?убÑ?танциÑ?, наричана плацебо. ... БГНЕС

Liraglutide helpt diabeteslijder afslanken  -  ‎Nov 4, 2009‎
Het medicijn is effectiever dan het afvalmiddel orlistat. PW meldt dat Deense onderzoekers in de online versie van The Lancet de resultaten bekend hebben ... Medical facts

Substância acelera perda de peso e com menos efeitos colaterais, indica teste  -  ‎Oct 22, 2009‎
...além do uso de liraglutida (em quatro doses diferentes) ou orlistat (conhecido como Xenical, o mais popular tratamento contra a obesidade) e placebo. ... O Globo

Une molécule réduirait l'obésité plus efficacement qu'Alli  -  ‎Oct 28, 2009‎
Une molécule, le liraglutide, permettrait de réduire le poids des personnes obèses ne souffrant pas de diabète, de façon plus efficace que l'orlistat, ... La République du Centre

Adipositas: Antidiabetikum lässt Pfund purzeln  -  ‎Oct 23, 2009‎
Damit bieten beide Wirkstoffe keinen Vorteil gegenüber Orlistat, das seit 1998 als Adipositasmedikament zugelassen ist und seine Wirkung im Darm erzielt. ... Deutsches Ärzteblatt

سؤال وجواب عن أدوية Ù?قدان الوزن  -  ‎Oct 30, 2009‎
اورليستات (Orlistat) يزيد من نقص المتناول من الشحوم وهذا بدوره ينقص السعرات الحرارية المتناولة وبالتالي لنقص الوزن ويجب أن ينبه المريض للالتزام بحمية قليلة ... الوقت البحرينية

糖尿病藥物促使體é‡?減輕  -  ‎Oct 31, 2009‎
...最新發表的研究中,沒有糖尿病的é?Žé‡?患者接å?—æ¯?天注射一次的liraglutide,減輕的體é‡?多於æœ?用å?£æœ?減é‡?藥物orlistat(在美國以Xenicalå’ŒAlli等商å“?å??販售)治療者。 ... 臺灣新浪網

أدوية Ù?قدان الوزن  -  ‎Nov 13, 2009‎
الأدوية الثلاثة مناسبة للاستخدام Ù?ÙŠ المرضى الذين يزيد مؤشر كتلة الجسم )حة( على 30 بالنسبة للـ «أورليستات» (Orlistat)ØŒ Ù?المريض بحاجة إلى إحداث نقص وزن على ... الوقت البحرينية

Lancet 온ë?¼ì?¸íŒ?ì—? 실려  -  ‎Oct 23, 2009‎
...체중ê°?량 약물ì?¸ 오르리스타트(orlistat, Xenical)보다 당뇨병 치료제ì?¸ 리ë?¼ê¸€ë£¨íƒ€ì?´ë“œ(liraglutide, Victoza)ê°€ 비만성ì?¸ì?˜ 체중 ê°?량 효과가 ë?” 좋다는 연구결과가 ... 메디게이트뉴스

살빼고 ì‹¶ì?€ 여성 제니칼 먹지마ë?¼?  -  ‎Oct 25, 2009‎
...주민우 기ìž? [헬스코리아뉴스] 지난 7ì›” 유럽ì—?서 당뇨병 치료제로 승ì?¸ì?„ ë°›ì?€ '빅토ìž?(Victoza/liraglutide)'ê°€ 비만치료제 '제니칼(Xenical/ orlistat,)' 보다 ... 헬스코리아뉴스

Läkemedel mot diabetes var effektivt som bantningsmedel  -  ‎Oct 22, 2009‎
Resultaten visar att patienterna som hade fått liraglutid minskade i vikt signifikant mer än dem som behandlades med placebo eller orlistat. ... Dagens Medicin

Slankemidlene Xenical og Alli og leverpÃ¥virkning  -  ‎Oct 27, 2009‎
Det er ikke dokumentert at slankemidler som inneholder orlistat (Xenical og Alli) fører til mer alvorlige leverproblemer enn det som allerede er beskrevet i ... Statens legemiddelverk

Nuevo fármaco te ayuda a reducir siete kilos en 20 semanas  -  ‎Oct 27, 2009‎
A distintos grupos se les administró liraglútido en cuatro dosis diferentes, orlistat, el tratamiento más popular contra la obesidad, o un placebo. La Raza

Un farmaco per il diabete per perdere peso  -  ‎Oct 26, 2009‎
...generalmente usato per il diabete di tipo II piuttosto che assumendo un farmaco a base di orlistat specifico per la riduzione del peso corporeo: è ... Sanihelp.it

Un nuovo farmaco ridurrebbe l'obesità del doppio rispetto ai normali farmaci  -  ‎Oct 25, 2009‎
E' stato rlevato che alte dosi di farmaco hanno avuto molto più successo rispetto alla pillola anti-obesità Orlistat oa una iniezione di placebo. ... In dies (Blog)

Los medicamentos para bajar de peso se venden sin controles  -  ‎Nov 8, 2009‎
En el mercado local, únicamente dos tipos de fármacos están autorizados para el expendio: Orlistat y Sibutramina (ver infografía). ... El Comercio (Ecuador)

תרופה חדשה להפחתה במשקל?!  -  ‎Oct 24, 2009‎
75% מהשמני×? לל×? סוכרת, שקבלו מנת תרופה גבוהה - 3 מ"×’, ירדו למעלה מ - 5% ממשקל×?, למול 30% בקבוצת הפלצבו, ו - 44% בקבוצתצכשיר להורדה במשקל - ORLISTAT. ... מרכז הרופאים המומחים

OBESITA': EFFICACE FARMACO CONTRO DIABETE, STUDIO  -  ‎Oct 23, 2009‎
I pazienti cui e' stato somministrato hanno perso il 44% del peso mentre i pazienti sotto l'effetto dell'orlistat sono dimagriti solo del 5%. ... L'Unità

Profesionales apuestan por aumentar los recursos para la investigación en ...  -  ‎Oct 27, 2009‎
...las unidades coronarias, la efectividad del Orlistat en el tratamiento de la obesidad o la hospitalización a domicilio como una alternativa asistencial. El Norte de Castilla

PERTE DE POIDS : Le second effet des nouveaux anti-diabétiques  -  ‎Oct 27, 2009‎
...(Université de Copenhague) a testé : C'est un effet perte de poids, plus efficace qu'un produit ciblé, comme l'orlistat (Xénical® de Roche et Alli® de GSK), ... santé log - communauté des professionnels de santé

ÖKO-TEST Jahrbuch Gesundheit für 2010  -  ‎Nov 8, 2009‎
Ihr Wirkstoff Orlistat hemmt die Spaltung der Fette im Dünndarm, sodass der Körper weniger Fett und Kalorien aufnimmt. Doch die Pille allein macht nicht ... Öko Test

Fármaco para la diabetes ayudaría a adelgazar  -  ‎Oct 27, 2009‎
Los adultos obesos adelgazarían más con un fármaco para tratar la diabetes llamado liraglutida que con el medicamento específico llamado orlistat (Xenical, ... Terra Perú

Adelgazantes causan males de mucho peso  -  ‎Oct 31, 2009‎
Entre las que suprimen el apetito la marca más conocida es Meridiay (Sibutramina), y de las que inhiben la grasa, Xenical (Orlistat). ... El Pais - Cali Colombia

¿La obesidad debe ser tratada sólo por médicos?  -  ‎Oct 22, 2009‎
Conoce las reacciones adversas de la sibutramina o el orlistat saben las contraindicaciones de estos fármacos. “La aplicación de los diferentes tipos de ... La Cronica del Quindio

Orlistat Approved for Over-the-Counter Sale  -  Feb 7, 2007
WEDNESDAY, Feb. 7 (HealthDay News) -- The US Food and Drug Administration has approved an over-the-counter version of orlistat, a prescription weight-loss ... Washington Post

FDA panel recommends Glaxo's drug Orlistat for over-the-counter sales...  -  Jan 24, 2006
LONDON (AFX) - A panel of doctors and scientists in the United States have recommended that the Food and Drug Administration approve over-the-counter sales ... Forbes

REFILE-UPDATE 1-Roche says out-licenses orlistat rights to Glaxo  -  Feb 20, 2007
ZURICH, Feb 20 (Reuters) - Swiss drugmaker Roche Holding AG (ROG.VX) said on Tuesday it had agreed to out-license the non-prescription rights to ... Reuters

Group: Diet Drug Alli Linked to Colon Cancer  -  Jun 14, 2007
The FDA approved orlistat, to be sold under the brand name Alli, ... Study participants took orlistat or a placebo three times daily with meals for 16 weeks ... FOXNews

Long-term persistence with orlistat and sibutramine in a population...  -  Sep 18, 2006
Correspondence: Dr R Padwal, Division of General Internal Medicine, 2E3.22 Walter C. Mackenzie Health Sciences Center, University of Alberta Hospital, ... Nature.com

FDA Questions a Planned Over-the-Counter Diet Drug  -  Jan 21, 2006
..."It is not clear to this reviewer what benefit a consumer purchasing orlistat OTC can possibly reap from six months of OTC use," the documents said. ... New York Times

Xenical Helps Obese Teens Shed Weight  -  Jun 15, 2005
Xenical, known generically as orlistat, produces weight loss by markedly reducing ... After that point, the average BMI held steady in the orlistat group ... ABC News

Weight-loss pill a wonder drug?: Orlistat receives mixed reviews...  -  Feb 12, 2007
Feb. 12--Lynn Moreau works out faithfully at Curves in Libbie Place in Henrico County and is a few workouts away from earning a T-shirt for her 300th ... Free with registration - Richmond Times - Dispatch - AccessMyLibrary.com

Weighing a Pill For Weight Loss  -  Jan 24, 2006
Orlistat was approved as a weight loss and weight maintenance drug by the FDA in ... "Orlistat is a very safe and effective drug with a long history of use ... Washington Post

GPs too busy to advise on exercise and diet – so hand out £47m in...  -  Feb 1, 2008
Two drugs, orlistat (Xenical) and sibutramine (Reductil), made up the bulk of recent ... Orlistat was licensed in Britain in 1998 and sibutramine in 2001. ... Times Online

Safety profile of orlistat: results of a prescription-event monitoring...  -  Aug 3, 2005
Correspondence: Dr LV Wilton, Drug Safety Research Unit, Bursledon Hall, Blundell Lane, Southampton SO31 1AA, UK. E-mail: lynda.wilton@dsru.org ... Nature.com

Group seeks to stop Xenical from going OTC  -  Apr 10, 2006
The FDA delayed approving orlistat in the late 1990s because of concerns that it ... Because orlistat blocks fat absorption, it can cause unpleasant bowel ... USA Today

Controversial diet drug approved  -  Jun 24, 2008
...they have tried and failed using alternative drugs such as orlistat. ... "This is good news for patients for whom orlistat and sibutramine are not ... BBC News

Obesity Drugs Work — Modestly  -  Nov 15, 2007
In one four-year trial, orlistat reduced the incidence of type 2 diabetes by ... Orlistat prompts weight loss by limiting the body's ability to absorb fat, ... TIME

Weighing in on orlistat: NO MAGIC PILL - Fat blocker's side effects...  -  Jan 31, 2006
With two-thirds of Americans now classified as overweight, there's no question there's a market for a drug proven to help block the body's fat absorption. ... $2.95 - Salt Lake Tribune, The - NewsBank

Effect of Orlistat on Eating Behavior Among Participants in a 3-year ...  -  Jan 16, 2007
To examine the effect of orlistat on dietary restraint, disinhibition, hunger, and binge eating and to understand the relation between changes in eating ... Nature.com

Roche, GlaxoSmithKline's Xenical found effective in US weight loss...  -  Oct 16, 2005
Orlistat patients also demonstrated significant decreases in total cholesterol, LDL cholesterol, systolic and diastolic blood pressure, according to a joint ... Forbes

So can a £1 pill from the chemist REALLY cure obesity?  -  Apr 17, 2008
The active ingredient in both drugs is orlistat, known as a lipase inhibitor. ... 'Orlistat acts only in the gut. But it potentially inhibits the absorption ... Daily Mail

THE LEAN PLATE; Weight loss drug is ally, not cure-all  -  Jan 30, 2006
In 1999, Orlistat was approved for use by obese people and by some ... GlaxoSmithKline Consumer Healthcare, maker of Orlistat, says that 22 million people ... Pay-Per-View - Los Angeles Times - ProQuest Archiver

… Examines Effects Of Over-The-Counter Strength Orlistat For Weight...  -  Jun 17, 2007
The first and only over-the-counter product for weight loss approved by the Food and Drug Administration was available from Friday, June 15. Orlistat ... Medical News Today - Medical News Today (press release)

Orlistat, a drug that decreases fat absorption, appears helpful for …  -  Jun 14, 2005
When combined with diet, exercise and behavioral therapy, orlistat, a drug that decreases fat absorption, appears helpful for improving weight management in ... News-Medical.net

Working of Xenical Orlistat  -  Jul 5, 2008
If you are tired of your unyielding weight and want to lose significant amount of weight, try Xenical orlistat. This is a prescription medication and does ... Buzzle

Panel Supports Offering Diet Pill Orlistat Over the Counter | Article...  -  Jan 24, 2006
Panel Supports Offering Diet Pill Orlistat Over the Counter ... find The Washington Post articles. A panel of doctors and scientists recommended yesterday ... Pay-Per-View - Washington Post - HighBeam Research

Despite failures, search for obesity drugs still looks golden  -  Nov 16, 2008
..."There are now just two drugs left, orlistat and sibutramine," said Dr Waine, ... Orlistat, marketed as Xenical or alli, curbs absorption of fat in the ... eTaiwan News

Compliance, Behavior Change, and Weight Loss With Orlistat in an Over...  -  Feb 26, 2007
The study was conducted to provide information on how consumers would use orlistat 60 mg, especially in terms of product dosing, in a setting without ... Nature.com

Diet drug offers multiple health benefit  -  Sep 8, 2006
NEW YORK - A low dose of the diet drug orlistat, coupled with a ... Orlistat 60 milligrams, which will be marketed as Alli (pronounced AL-eye) is a low-dose ... 中国日报 - 中国日报

Orlistat (Oral -- Local ).  -  Oct 27, 2005
Orlistat(OR-li-stat ) is used as an aid to help you lose weight. The medicine prevents the digestion of some of the fat you eat. Fats that are not digested ... Free with registration - USP DI-Volume II, Advice for the... - AccessMyLibrary.com

FDA OKs first non-prescription diet pill  -  Mar 2, 2007
When taken with meals the drug — known generically as orlistat — blocks the ... "OTC orlistat, along with diet and exercise, may aid overweight adults who ... USA Today

Low-dose Orlistat helps in fat war -- but heed warning; EAT WELL  -  May 16, 2006
Q: Did I read that there is a new over-the-counter drug that will help with weight loss? A: The magic weight-loss pill does not exist, but there are some ... Pay-Per-View - Miami Herald - Factiva, from Dow Jones

A Case Series Describing Orlistat Use in Patients on Psychotropic …  -  Jan 15, 2005
Weight gain induced by long-term psychopharmacotherapy has emerged as a relevant clinical issue because it affects compliance and long-term outcome. ... RedOrbit

Critics Trash FDA's OTC Approval of Orlistat  -  Feb 9, 2007
By Truman Lewis. Federal approval of an over-the-counter version of orlistat weight-loss capsules drew rave press notices this week despite critics who say ... Consumer Affairs

Novo Nordisk's Liraglutide Sustained Weight Loss  -  Jun 16, 2008
That compared with weight loss of up to 4 kilograms for patients taking orlistat. Novo Nordisk has tested liraglutide as an obesity and a diabetes drug. ... Bloomberg

EDITORIAL: Over the Counter Diet Drug A fat pill with worries.(Editori...  -  Jan 28, 2006
The latest effort, orlistat, by Glaxo SmithKline Consumer Health, received preliminary ... Glaxo argues that orlistat, marketed as Alli, will be the first ... Free with registration - Philadelphia Inquirer - AccessMyLibrary.com

Long-term data needed on anti-obesity drugs  -  Jan 5, 2007
Orlistat reduces weight by an average of 3 kilograms, ... Treatment with orlistat is associated with frequent gastrointestinal side effects, sibutramine may ... Reuters

Orlistat Most Effective Antiobesity Drug for Reducing Blood Pressure...  -  May 22, 2008
By Timothy A. O'Leary. GENEVA -- May 22, 2008 -- The antiobesity drug orlistat reduces blood pressure, total cholesterol, and low-density lipoprotein (LDL) ... DG News

Review: Fluoxetine, Orlistat, and Sibutramine Modestly Reduce Weight...  -  Jan 25, 2005
Norris SL, Zhang X, Avenell A, et al. Efficacy of pharmacotherapy for weight loss in adults with type 2 diabetes mellitus: a meta- analysis. ... RedOrbit

The Safety Profiles of Orlistat and Sibutramine: Results of Prescripti...  -  Nov 8, 2006
Correspondence: Michael Perrio Drug Safety Research Unit, Bursledon Hall, Blundell Lane, Southampton, United Kingdom S031 1AA. E-mail: michael.perrio@dsru. ... Nature.com

Medication orlistat appears helpful in improving weight management...  -  Jun 19, 2005
When combined with diet, exercise and behavioral therapy, orlistat, a drug that decreases fat absorption, appears helpful for improving weight management in ... i-newswire.com

Preventing "horsewoman's tan"  -  Jun 22, 2008
A: Alli is over-the-counter orlistat. It has been prescribed under the name Xenical. Diarrhea and increased bowel movements are common side effects of ... Seattle Times

A miracle drug? Alli packs plenty of pros, cons  -  Jun 20, 2007
Orlistat, the active ingredient in Alli, has been used by an estimated 28 ... After one year, individuals in the orlistat group lost an average of 19.27 ... Pay-Per-View - Chicago Tribune - ProQuest Archiver

Sweet pill  -  Jan 25, 2006
..."Glaxo Smithkline's weight-loss pill Orlistat is set to become the only ... Orlistat is already sold as a prescription medicine under the brand name Xenical ... Telegraph.co.uk

… shows drug helps obese teenagers lose weight; Orlistat's side...  -  Jun 15, 2005
Obese teenagers who took orlistat, a drug that blocks fat absorption in the body, ... The majority of the patients on orlistat experienced moderate ... Pay-Per-View - Washington Times - HighBeam Research

Ryckman: Lose weight or lose control  -  Feb 20, 2007
Remember, orlistat works by blocking absorption of fat. And it's gotta come out somewhere. • Dr. David Katz, director of the Yale Prevention Research Center ... Rocky Mountain News

Weighing a Pill For Weight Loss | Article from The Washington Post | ...  -  Jan 24, 2006
Orlistat was approved as a weight loss and weight maintenance drug by the FDA in ... "Orlistat is a very safe and effective drug with a long history of use ... Pay-Per-View - Washington Post - HighBeam Research

Billions Spent On Quack Health Foods That Don't Help Weight Loss Or …  -  Nov 26, 2008
He said that of all the hundreds of products currently on sale to help people lose weight, only the drugs orlistat and sibutramine, and in some cases ... Sky News

Orlistat Cuts Pounds, Cholesterol Levels: Study  -  Jan 10, 2005
The prescription weight-loss drug orlistat helps obese adults shed pounds and lower their cholesterol levels -- including those with diabetes or other risk ... Virtual Medical Centre - The Virtual Medical Centre

GSK Receives Positive Opinion For Alli(R) (orlistat 60 Mg) As A Non- …  -  Oct 24, 2008
Thursday 23 October 2008, London GlaxoSmithKline (GSK) announced today that alli (orlistat 60 mg) has received a positive opinion as a non-prescription ... Medical News Today - Medical News Today (press release)

New Nonprescription Weight Loss Product: Orlistat  -  Jun 25, 2007
Orlistat debuted as Xenical 120-mg capsules in 1999. [9] Its mechanism of action is inhibition of gastric and pancreatic lipases in the stomach lumen and ... Medscape

Article: Health: Weightwatcher.(orlistat)(Brief Article) - Newsweek |...  -  Feb 6, 2006
Health: Weightwatcher.(orlistat)(Brief Article) ... find Newsweek articles. Byline: Karen Springen Should you take the weight-loss drug orlistat? Pay-Per-View - Newsweek - HighBeam Research

EU regulators back Glaxo's OTC obesity treatment  -  May 25, 2007
The European Medicines Agency said on Friday its experts had recommended granting marketing authorisation for Glaxo's version of orlistat -- the active ... Reuters

Orlistat Improves Weight Management in Obese Adolescents  -  Oct 15, 2005
Synopsis: Investigators identified 539 adolescents, 12 to 16 years of age, who met the criteria for obesity (a body mass index [BMI] of more than two units ... AAFP News Now

Orlistat Effective for Obese Adolescents With Menstrual Disorders: …  -  May 21, 2008
By Timothy O'Leary. GENEVA -- May 21, 2008 -- Weight-loss therapy with the anti-obesity drug orlistat is an effective first option for obese adolescents ... DG News

Doubts over obesity pill claims  -  May 29, 2007
The DTB paper stated: "Orlistat is the drug for obesity for which there is the most evidence for efficacy and safety to date, and we have previously ... BBC News

Over-counter sales of diet pill near OK  -  Apr 8, 2006
That interim step means the over-the-counter form of orlistat is eligible ... If the FDA approves orlistat as a nonprescription drug, it would become the ... Boston Globe

Weight-loss drug gets OK  -  Mar 6, 2007
Since 1999, orlistat has been available in the United States in the form of a prescription ... The over-the-counter version of orlistat, marketed as Alli, ... $2.95 - Buffalo News - NewsBank

Low-Dose Orlistat Data Show Weight Loss, Improved Lipids and Blood …  -  Sep 12, 2006
According to 3 recent double-blind placebo-controlled studies, low-dose orlistat (60 mg), coupled with a reduced-calorie diet, leads to significant weight ... Diabetes In Control

CUSTOMIZING ORLISTAT JUST FOR YOU AND YOUR DIET  -  Jan 25, 2006
BY BREANNE L. HELDMAN. Although safe, Orlistat produces some unpleasant side effects. The fat it removes from ingested food ends up in the stool, ... New York Daily News

Weight Loss Can Control Hypertension  -  Sep 28, 2007
Some also were prescribed orlistat, a drug that prevents fat from being metabolized. After six months, 53 percent of the men and 49 percent of the women in ... Washington Post

Orlistat Aids Weight Management in Adolescents  -  Aug 31, 2005
Can reducing intestinal fat absorption by pharmacotherapy aid weight management in adolescents? This multicenter, randomized double-blind placebo-controlled ... Medscape

… the thioesterase domain of human fatty acid synthase inhibited by...  -  Jul 8, 2007
...(a) Hydrolyzed Orlistat within the active site of chain B, depicted as in Figure 2. Shown covering the Orlistat product is the F o – F c simulated-annealing ... Nature.com

Orlistat Marketed as Alli is a Big, Fat Lie  -  Oct 26, 2007
...(NaturalNews) Every year more than 70 million people resolve to lose weight by going on a diet, which feeds the big, fat $58 billion diet and weight-loss ... Natural News.com

New over-the-counter diet medication offers hope, concerns.  -  Feb 15, 2007
Orlistat has been available since 1999 by prescription under the name Xenical. ... Alli and orlistat users are advised to take a vitamin supplement, ... Free with registration - Chattanooga Times/Free Press (Chattanoog... - AccessMyLibrary.com

Evaluation of Urinary Oxalate Levels in Patients Receiving …  -  Dec 29, 2006
While the patients in group I (n = 55) were treated with orlistat ... Although this specific effect of orlistat has been evaluated in the rat model (15), ... Nature.com

OTC orlistat poses potential drug interactions.(News)  -  Feb 15, 2006
BETHESDA, MD. -- The advisory panel that gave near-unanimous support for making orlistat available without a prescription also voiced several concerns about ... Free with registration - Family Practice News - AccessMyLibrary.com

For health, there's no pill to replace willpower.  -  Feb 6, 2006
The over-the-counter version of orlistat will be a lower dosage than Xenical, ... No one is calling orlistat a miracle drug, just an "aid" to those who are ... Free with registration - San Jose Mercury News - AccessMyLibrary.com

FDA committee to review GSK proposal for orlistat capsules for OTC...  -  Jan 1, 2006
GlaxoSmithKline Consumer Healthcare anticipates that on January 23, 2006, the FDA's joint Nonprescription Drugs and Endocrinologic and Metabolic Drugs ... Free with registration - Pharmaceutical Processing - AccessMyLibrary.com

Orlistat weight loss drug points to new cancer treatments  -  Jul 9, 2007
Based on their surprising discovery that an obesity drug can kill cancer cells, scientists at Wake Forest University School of Medicine have made a new ... News-Medical.net

FAT-BLOCKING GUT-BUSTER  -  Jan 25, 2006
But Orlistat - to be dubbed Alli, if the Food and Drug Administration ... Orlistat works best for people who stick to a low-fat diet - and causes the most ... New York Daily News

Xenical may be sold over-the-counter  -  Nov 8, 2005
Xenical, also known by the generic name orlistat, was approved as a ... Orlistat users who lost weight also had significant decreases in the total ... Pay-Per-View - Newsday - ProQuest Archiver

Study Results Found Low-Dose Orlistat (60 Mg) Demonstrates Significant...  -  Oct 22, 2006
BOSTON and PITTSBURGH, Oct. 22 /PRNewswire/ -- Data presented today at the 2006 Annual Scientific Meeting of NAASO, The Obesity Society, found that low-dose ... RedOrbit

Satisfy your hunger on 15 grams of fat per meal  -  Jun 21, 2007
Last week, the first FDA-approved weight-loss drug, Alli ( pronounced al-eye), once sold by prescription as Xenical (orlistat), hit store shelves. ... Atlanta Journal Constitution

Orlistat for obesity  -  Apr 20, 2007
Orlistat prevents your intestines from absorbing some of the fat from the food you eat. When taken 3 times per day with meals, orlistat blocks about ... MSN Health & Fitness

… Exclusive Rights To Over-the-counter Orlistat For Markets Outside...  -  Feb 25, 2007
GSK anticipates filing orlistat for OTC approval in Europe and certain key ... Earlier this month, GSK received FDA approval to market OTC orlistat in the ... Medical News Today - Medical News Today (press release)

Orlistat (Oral -- Local ).(Drug overview)  -  Aug 1, 2006
Orlistat(OR-li-stat ) is used as an aid to help you lose weight. The medicine prevents the digestion of some of the fat you eat. Fats that are not digested ... Free with registration - USP DI-Volume II, Advice for the... - AccessMyLibrary.com

Small Changes, Big Benefits - You don't have to break a sweat to...  -  Feb 20, 2006
Orlistat gives many people diarrhea, but the only side effect of walking is good health. Want to lose more or lose faster? You can double your losses by ... $2.95 - Newsweek - NewsBank

Dieting and Medication May Reduce Blood Pressure in Patients With …  -  Mar 24, 2008
..."Patients assigned to weight-loss diets, orlistat, or sibutramine reduced their body weight more effectively than did patients in the usual care/placebo ... DG News

Article: No magic pill Diet drug orlistat awaits OK for over-the...  -  Jan 31, 2006
No magic pill Diet drug orlistat awaits OK for over-the-counter sales.(Spotlight) ... find Rocky Mountain News (Denver, CO) articles. Pay-Per-View - Rocky Mountain News - HighBeam Research

Weight-loss drug not sole fat solution  -  Mar 29, 2006
The Food and Drug Administration is considering a proposal that would take orlistat, sold by Roche Pharmaceuticals under the brand Xenical, over the counter ... United Press International

Diet drug debuting with big splash  -  Jun 8, 2007
Orlistat is sold in prescription form under the name Xenical. The drug helps users lose weight by reducing by about 25 percent the amount of fat the body ... Pittsburgh Post-Gazette - Pittsburgh Post Gazette

Orlistat wins approval as OTC weight-loss drug: the thrice-daily drug...  -  Mar 1, 2007
Orlistat will soon be available to consumers without a prescription, making it the first weight-loss product available over the counter that has been ... $4.95 - Internal Medicine News - ECNext

Orlistat may be helpful in treatment of polycystic ovaries.(News)  -  May 15, 2005
The weight loss drug orlistat may prove to be a useful adjunct in the treatment of polycystic ovarian syndrome, according to findings from a small ... Free with registration - Family Practice News - AccessMyLibrary.com

GPs accused of ignoring obesity drug side effects  -  May 21, 2007
Prescriptions for the two main anti- obesity medicines, orlistat and ... Annual orlistat prescriptions rose from 17800 to 646700 between 1998 and 2005 - a ... Daily Mail

How to take Orlistat from Consumer Reports Health.  -  Jan 8, 2007
...tell your doctor and pharmacist if you are allergic to orlistat or any other medications. talk to your doctor if you are taking medications that suppress ... consumerreports.org

Weighed down by a pill  -  Jun 22, 2007
He points out that one needs oral supplements to make up for the loss of vitamin A, D and E that Orlistat causes. The only other anti-obesity salt that was ... Indian Express

OTC orlistat poses potential drug interactions.(News) | Article from...  -  Feb 15, 2006
OTC orlistat poses potential drug interactions.(News) ... find Family Practice News articles. BETHESDA, MD. -- The advisory panel that gave near-unanimous ... Pay-Per-View - Family Practice News - HighBeam Research

Article: FDA panel backs OTC orlistat, with some concern: the...  -  Feb 15, 2006
FDA panel backs OTC orlistat, with some concern: the advisory panel was troubled about the drug's interactions with warfarin and cyclosporine. Pay-Per-View - OB GYN News - HighBeam Research

Orlistat, Lifestyle Counseling Help Maintain 3-Year Weight Loss...  -  Oct 24, 2006
October 24, 2006 (Boston) -- A randomized, placebo-controlled study shows that orlistat ( Xenical) coupled with lifestyle counseling helps obese patients ... Medscape

Article: FDA panel endorses OTC approval of orlistat: the weight loss...  -  Feb 15, 2006
FDA panel endorses OTC approval of orlistat: the weight loss drug's potential for interactions with cyclosporine and warfarin prompted concern. ... find ... Pay-Per-View - Internal Medicine News - HighBeam Research

THE DIET PILL DILEMMA ; RESEARCHERS TRYING TO BUILD A …  -  Feb 23, 2007
Glaxo plans to market Orlistat under the name Alli. ... Wolfe requested that the FDA reject Orlistat as an over-the- counter drug because studies showed ... Pay-Per-View - The Sun - ProQuest Archiver

Article: Weight-loss drug orlistat backed for OTC status: an FDA...  -  Mar 1, 2006
Weight-loss drug orlistat backed for OTC status: an FDA advisory panel has recommended OTC approval of the drug, which reduces fat absorption. Pay-Per-View - Clinical Psychiatry News - HighBeam Research

Dieting And Medication May Reduce Blood Pressure In Patients With …  -  Mar 25, 2008
..."Patients assigned to weight loss diets, orlistat or sibutramine reduced their body weight more effectively than did patients in the usual care/placebo ... sciencedaily.com

Orlistat Potentiates Weight Loss Without Affecting Eating Behaviour: ...  -  Apr 24, 2007
By Thomas S. May. BUDAPEST, HUNGARY -- April 24, 2007 -- Results of a three-year clinical study show there is no significant difference in eating behaviour ... DG News

Learn about Orlistat from Consumer Reports Health.  -  Jan 8, 2007
Orlistat (prescription and nonprescription) is used with an individualized low-calorie, low-fat diet and exercise program to help people lose weight . ... consumerreports.org

Orlistat - the only non-controlled anti-obesity prescription drug...  -  Nov 4, 2006
Obesity refers to an excessive amount of body fat. Most health care professionals agree that men with more than 25 percent body fat and women with more than ... Buzzle

Some who reduce weight reduce hypertension  -  Oct 1, 2007
...diet was designed for each patient and when diet alone did not achieve the appropriate body weight reduction, the weight-loss drug Orlistat was given. ... United Press International

Orlistat and Metformin Protect Against Antidepressant-Associated...  -  Mar 27, 2006
By Fran Lowry. MIAMI, FL -- March 27, 2006 -- Adjunctive use of both orlistat and metformin produced an improvement in body weight and body mass index (BMI) ... DG News

… to petition to ban diet drug orlistat (XENICAL). Additional...  -  Jun 5, 2006
This letter, based on an investigation published in the current issue of the Cancer Letter ("FDA Didn't Tell Advisors About Data Linking Obesity Drug With ... Public Citizen - Auto Safety & Consumer...

Scheduling Of Orlistat - National Drugs And Poisons Schedule Committee...  -  Feb 27, 2007
The National Drugs and Poisons Schedule Committee (NDPSC) reconsidered the scheduling and advertising status of orlistat (contained in the medicine Xenical) ... Medical News Today - Medical News Today (press release)

FDA questions on long term benefits of Orlistat  -  Jan 21, 2006
By FDA Advisory Committee, [RxPG] Efficacy concerns surrounding GlaxoSmithKline's orlistat may prove to be a bigger hurdle to overcome than safety or ... RxPG NEWS

Fat-blocking drug isn't the right answer  -  Feb 13, 2006
The drug, a fat blocker, already sells in the prescription form Orlistat. ... "There is no magic pill for weight loss, and Orlistat is not a magic pill," ... $2.95 - The Gazette - NewsBank

Brand Names/Synonyms:
Orlistat is also known by the following brand names and/or synonymsOrlipastat; Orlipastatum [Inn-Latin]; Orlistat; Orlistat [Usan:Inn]; Tetrahydrolipstatin; Xenical

Drug Category:
Orlistat is categorized under the following by the FDA: Antiobesity Agents; Enzyme Inhibitors; ATC:A08AB01

Dosage Forms:
CAPSULE

Absorption:
Not Available

Interactions:
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Chemical IUPAC Name:
1-[(3-hexyl-4-oxo-oxetan-2-yl)methyl]dodecyl2-formylamino-4-methyl-pentanoate





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