Orlistat

This page contains recent news articles, when available, and an overview of Orlistat but does not offer medical advice. You should contact your physician with regard to any health issues or concerns.


Overview:

Orlistat
(when available)

Pharmacology and use:
Orlistat is a lipase inhibitor used for obesity management that acts by inhibiting the absorption of dietary fats. For the treatment of Obesity including management of weight loss and weight maintenance

Mechanism Of Action:
Orlistat is a reversible inhibitor of lipases. It exerts its therapeutic activity in the lumen of the stomach and small intestine by forming a covalent bond with the active serine residue site of gastric and pancreatic lipases. The inactivated enzymes are thus unavailable to hydrolyze dietary fat in the form of triglycerides into absorbable free fatty acids and monoglycerides. As undigested triglycerides are not absorbed, the resulting caloric deficit may have a positive effect on weight control.

News Articles on Orlistat

Liraglutide treatment led to greater reduction in body weight than placebo ...  -  ‎Oct 26, 2009‎
Those assigned to placebo lost a mean 2.8 kg and those assigned to orlistat lost a mean 4.1 kg. In comparison, participants assigned to liraglutide lost a ... Endocrine Today

Get effective Obesity Treatment through Xenical Weight loss pills  -  ‎Nov 11, 2009‎
Xenical, active ingredient orlistat, is a highly effective weight loss pill used by men and women. A product of Roche laboratories, it can help you to ... Best Syndication

On the Pulse - 13th November 2009  -  ‎Nov 13, 2009‎
By comparison, those substituting liraglutide with placebo lost only 2.8 kg, and those receiving orlistat, 4.1 kg. An accompanying Comment observes that the ... OnMedica

Looking for an ally? Take a pill  -  ‎Oct 29, 2009‎
One such weight loss drug garnering interest is Orlistat (also known as tetrahydrolipstatin). It's already being marketed in the Philippines under the trade ... BusinessWorld Online

Fears emerge over weight-loss drug's links with kidney damage  -  ‎Nov 2, 2009‎
Alli, also known as Orlistat, became the first weight-loss drug approved by the Food and Drugs Administration in the US to be sold over the counter in 2007. ... Irish Times

How a new drug helps one lose weight the healthy way  -  ‎Nov 9, 2009‎
That's where Orlistat (Alli) steps in. “Alli helps boost weight loss. For every two pounds you lose, Alli helps you lose one pound more. ... Inquirer.net

Weight loss ally supports healthy lifestyle options  -  ‎Nov 9, 2009‎
Orlistat (alli) t helps boost weight loss. So for every two pounds you lose on your own, the formulation helps you lose one pound more. ... Malaya

New weight loss drugs on the horizon!  -  ‎Nov 7, 2009‎
In addition to the two medications currently available (Sibutramine (Meridia) and Orlistat (Xenical)), there are at least three new medications that are in ... Drumheller Mail

Effects of liraglutide in the treatment of obesity: a randomised, double-blind ...  -  ‎Oct 30, 2009‎
In the trial, 564 patients were randomized to one of six groups: orlistat (120 mg, 3 times daily), placebo, and liraglutide 1.2 mg, 1.8 mg, 2.4 mg, ... Gerson Lehrman Group

LC: Speech bySFH on Pharmacy and Poisons Ordinance  -  ‎Oct 22, 2009‎
In addition, the Pharmacy and Poisons Board proposes to relax the control of "orlistat when contained in pharmaceutical products the recommended daily dose ... 7thSpace Interactive (press release)

New Prescription Diet Pills Coming Soon  -  ‎Oct 23, 2009‎
Orlistat is sold in a lower dose over-the-counter, like Alli. The Food and Drug Administration is reviewing safety information regarding reports of ... That's Fit

Victoza yields substantial weight loss in diabetic patients, study finds  -  ‎Oct 26, 2009‎
...(liraglutide) in a 1.2 mg, 1.8mg, 2.4 mg or 3 mg dose, GlaxoSmithKline's weight-loss drug Alli (orlistat) in a 120 mg dose or placebo three times a day. ... Drug Store News (blog)

Too fat? Weigh up risks of gastric band  -  ‎Nov 11, 2009‎
For example, orlistat - which stops you absorbing fat - can cause gut problems like wind or leakage. An alternative, sibutramine, is an appetite-suppressant ... The Sun

Jeremy Laurance: A breakthrough – but the real answer lies in exercise and diet  -  ‎Oct 22, 2009‎
This could give it the edge over sibutramine, which raises blood pressure, and orlistat, which has unpleasant, although not unsafe, effects on the digestion ... Independent

New Diabetes Drug Helps Obese Adults With Weight Loss  -  ‎Oct 26, 2009‎
One group received the weight loss medication orlistat, found in the currently available medications Xenical and Alli. The control group received a placebo. ... eMaxHealth

Adherence to the Mediterranean Diet Moderates the Association of ...  -  ‎Oct 22, 2009‎
Harrison SA, Fecht W, Brunt EM, Neuschwander-Tetri BA: Orlistat for overweight subjects with nonalcoholic steatohepatitis: A randomized, prospective trial. ... Medscape

Nueva promesa en la batalla antiobesidad  -  ‎Oct 22, 2009‎
Según los resultados de un estudio preliminar, el fármaco podría ser más efectivo -en su dosis más alta- que el ya comercializado orlistat. ... elmundo.es

Übergewicht und Bluthochdruck: Unheiliges Duo  -  ‎Nov 12, 2009‎
Für Orlistat zeigte sich eine Gewichtsabnahme von im Mittel 3,7 kg, für Sibutramin von 3,4 kg. Bei der Reduzierung des Blutdruckes berichtet das IQWiG für ... MedizinAuskunft

Droga contra la diabetes que adelgaza  -  ‎Oct 23, 2009‎
Un portavoz de GlaxoSmithKline, que produce orlistat, dijo que la comparación era injusta pues las drogas fueron administradas en diferentes dosis y maneras ... BBC Mundo

FDA onderzoekt meldingen van leverschade door orlistat  -  ‎Oct 23, 2009‎
De Amerikaanse Food and Drug Administration (FDA) onderzoekt een mogelijk verband tussen het gebruik van het vermageringsmiddel orlistat en het optreden van ... Gezondheid.be

Bien trop tôt pour crier Victoza  -  ‎Oct 26, 2009‎
Comparé à l'orlistat (Xenical, Alli), ce dernier pourrait s'avérer un blockbuster sans précédent… avec un impact moyen de 9% sur le poids par rapport à la ... Bloob

Hilft Liraglutid Nichtdiabetikern beim Abnehmen?  -  ‎Nov 9, 2009‎
Verglichen wurde die Therapie mit Liraglutid in den Dosierungen 1,2 mg, 1,8 mg, 2,4 mg und 3,0 mg einmal täglich subkutan, mit Placebo und mit Orlistat in ... Ärzte Zeitung

Trois millions de nouveaux obèses en France  -  ‎Nov 13, 2009‎
Financée par Roche -qui commercialise le traitement de l'obésité Xenical* (orlistat)-, l'enquête est réalisée par TNS Healthcare Sofres. ... Mondesante.com

시오노기 항비만제 복합제 개발 추진  -  ‎Nov 9, 2009‎
...ì?¼ë³¸ 시오노기제약ì?€ 미국ì—?서 후기2ìƒ? ìž„ìƒ? 중ì?¸ 항비만제 'S-2367'(velneperit)ì—? 대해 체중ê°?소 효과를 높ì?´ê¸° 위해 GSKì?˜ 항비만제 '오를리스타트'(orlistat)와ì?˜ ... 메디파나뉴스

Un medicament antidiabetic ajută obezii să slăbească  -  ‎Oct 26, 2009‎
...al doilea grup a primit Orlistat, un medicament împotriva obezităţii comercializat sub numele de Xenical, iar al treilea grup a primit un placebo. ... Anima News

Thuốc mập, thuốc ốm  -  ‎Nov 12, 2009‎
...thá»±c phẩm Mỹ chấp thuận dùng trong Ä‘iá»?u trị và ở ta cÅ©ng thưá»?ng hay chỉ định dùng cho ngưá»?i cần làm ốm là orlistat (Xenical) và sibutramin (Reductil). ... Người Lao Động

ЛекарÑ?тво за диабет бори и затлъÑ?Ñ‚Ñ?ването  -  ‎Oct 22, 2009‎
Първата получавала дневно liraglutide на четири различни дози; втората - orlistat; на третата учените давали безвредна Ñ?убÑ?танциÑ?, наричана плацебо. ... БГНЕС

Liraglutide helpt diabeteslijder afslanken  -  ‎Nov 4, 2009‎
Het medicijn is effectiever dan het afvalmiddel orlistat. PW meldt dat Deense onderzoekers in de online versie van The Lancet de resultaten bekend hebben ... Medical facts

Substância acelera perda de peso e com menos efeitos colaterais, indica teste  -  ‎Oct 22, 2009‎
...além do uso de liraglutida (em quatro doses diferentes) ou orlistat (conhecido como Xenical, o mais popular tratamento contra a obesidade) e placebo. ... O Globo

Une molécule réduirait l'obésité plus efficacement qu'Alli  -  ‎Oct 28, 2009‎
Une molécule, le liraglutide, permettrait de réduire le poids des personnes obèses ne souffrant pas de diabète, de façon plus efficace que l'orlistat, ... La République du Centre

Adipositas: Antidiabetikum lässt Pfund purzeln  -  ‎Oct 23, 2009‎
Damit bieten beide Wirkstoffe keinen Vorteil gegenüber Orlistat, das seit 1998 als Adipositasmedikament zugelassen ist und seine Wirkung im Darm erzielt. ... Deutsches Ärzteblatt

سؤال وجواب عن أدوية Ù?قدان الوزن  -  ‎Oct 30, 2009‎
اورليستات (Orlistat) يزيد من نقص المتناول من الشحوم وهذا بدوره ينقص السعرات الحرارية المتناولة وبالتالي لنقص الوزن ويجب أن ينبه المريض للالتزام بحمية قليلة ... الوقت البحرينية

糖尿病藥物促使體é‡?減輕  -  ‎Oct 31, 2009‎
...最新發表的研究中,沒有糖尿病的é?Žé‡?患者接å?—æ¯?天注射一次的liraglutide,減輕的體é‡?多於æœ?用å?£æœ?減é‡?藥物orlistat(在美國以Xenicalå’ŒAlli等商å“?å??販售)治療者。 ... 臺灣新浪網

أدوية Ù?قدان الوزن  -  ‎Nov 13, 2009‎
الأدوية الثلاثة مناسبة للاستخدام Ù?ÙŠ المرضى الذين يزيد مؤشر كتلة الجسم )حة( على 30 بالنسبة للـ «أورليستات» (Orlistat)ØŒ Ù?المريض بحاجة إلى إحداث نقص وزن على ... الوقت البحرينية

Lancet 온ë?¼ì?¸íŒ?ì—? 실려  -  ‎Oct 23, 2009‎
...체중ê°?량 약물ì?¸ 오르리스타트(orlistat, Xenical)보다 당뇨병 치료제ì?¸ 리ë?¼ê¸€ë£¨íƒ€ì?´ë“œ(liraglutide, Victoza)ê°€ 비만성ì?¸ì?˜ 체중 ê°?량 효과가 ë?” 좋다는 연구결과가 ... 메디게이트뉴스

살빼고 ì‹¶ì?€ 여성 제니칼 먹지마ë?¼?  -  ‎Oct 25, 2009‎
...주민우 기ìž? [헬스코리아뉴스] 지난 7ì›” 유럽ì—?서 당뇨병 치료제로 승ì?¸ì?„ ë°›ì?€ '빅토ìž?(Victoza/liraglutide)'ê°€ 비만치료제 '제니칼(Xenical/ orlistat,)' 보다 ... 헬스코리아뉴스

Läkemedel mot diabetes var effektivt som bantningsmedel  -  ‎Oct 22, 2009‎
Resultaten visar att patienterna som hade fått liraglutid minskade i vikt signifikant mer än dem som behandlades med placebo eller orlistat. ... Dagens Medicin

Slankemidlene Xenical og Alli og leverpÃ¥virkning  -  ‎Oct 27, 2009‎
Det er ikke dokumentert at slankemidler som inneholder orlistat (Xenical og Alli) fører til mer alvorlige leverproblemer enn det som allerede er beskrevet i ... Statens legemiddelverk

Nuevo fármaco te ayuda a reducir siete kilos en 20 semanas  -  ‎Oct 27, 2009‎
A distintos grupos se les administró liraglútido en cuatro dosis diferentes, orlistat, el tratamiento más popular contra la obesidad, o un placebo. La Raza

Un farmaco per il diabete per perdere peso  -  ‎Oct 26, 2009‎
...generalmente usato per il diabete di tipo II piuttosto che assumendo un farmaco a base di orlistat specifico per la riduzione del peso corporeo: è ... Sanihelp.it

Un nuovo farmaco ridurrebbe l'obesità del doppio rispetto ai normali farmaci  -  ‎Oct 25, 2009‎
E' stato rlevato che alte dosi di farmaco hanno avuto molto più successo rispetto alla pillola anti-obesità Orlistat oa una iniezione di placebo. ... In dies (Blog)

Los medicamentos para bajar de peso se venden sin controles  -  ‎Nov 8, 2009‎
En el mercado local, únicamente dos tipos de fármacos están autorizados para el expendio: Orlistat y Sibutramina (ver infografía). ... El Comercio (Ecuador)

תרופה חדשה להפחתה במשקל?!  -  ‎Oct 24, 2009‎
75% מהשמני×? לל×? סוכרת, שקבלו מנת תרופה גבוהה - 3 מ"×’, ירדו למעלה מ - 5% ממשקל×?, למול 30% בקבוצת הפלצבו, ו - 44% בקבוצתצכשיר להורדה במשקל - ORLISTAT. ... מרכז הרופאים המומחים

OBESITA': EFFICACE FARMACO CONTRO DIABETE, STUDIO  -  ‎Oct 23, 2009‎
I pazienti cui e' stato somministrato hanno perso il 44% del peso mentre i pazienti sotto l'effetto dell'orlistat sono dimagriti solo del 5%. ... L'Unità

Profesionales apuestan por aumentar los recursos para la investigación en ...  -  ‎Oct 27, 2009‎
...las unidades coronarias, la efectividad del Orlistat en el tratamiento de la obesidad o la hospitalización a domicilio como una alternativa asistencial. El Norte de Castilla

PERTE DE POIDS : Le second effet des nouveaux anti-diabétiques  -  ‎Oct 27, 2009‎
...(Université de Copenhague) a testé : C'est un effet perte de poids, plus efficace qu'un produit ciblé, comme l'orlistat (Xénical® de Roche et Alli® de GSK), ... santé log - communauté des professionnels de santé

ÖKO-TEST Jahrbuch Gesundheit für 2010  -  ‎Nov 8, 2009‎
Ihr Wirkstoff Orlistat hemmt die Spaltung der Fette im Dünndarm, sodass der Körper weniger Fett und Kalorien aufnimmt. Doch die Pille allein macht nicht ... Öko Test

Fármaco para la diabetes ayudaría a adelgazar  -  ‎Oct 27, 2009‎
Los adultos obesos adelgazarían más con un fármaco para tratar la diabetes llamado liraglutida que con el medicamento específico llamado orlistat (Xenical, ... Terra Perú

Adelgazantes causan males de mucho peso  -  ‎Oct 31, 2009‎
Entre las que suprimen el apetito la marca más conocida es Meridiay (Sibutramina), y de las que inhiben la grasa, Xenical (Orlistat). ... El Pais - Cali Colombia

¿La obesidad debe ser tratada sólo por médicos?  -  ‎Oct 22, 2009‎
Conoce las reacciones adversas de la sibutramina o el orlistat saben las contraindicaciones de estos fármacos. “La aplicación de los diferentes tipos de ... La Cronica del Quindio

Brand Names/Synonyms:
Orlistat is also known by the following brand names and/or synonyms:
Orlipastat; Orlipastatum [Inn-Latin]; Orlistat; Orlistat [Usan:Inn]; Tetrahydrolipstatin; Xenical

Drug Category:
Orlistat is categorized under the following by the FDA: Antiobesity Agents; Enzyme Inhibitors; ATC:A08AB01

Dosage Forms:
CAPSULE

Absorption:
Not Available

Interactions:
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Chemical IUPAC Name:
1-[(3-hexyl-4-oxo-oxetan-2-yl)methyl]dodecyl2-formylamino-4-methyl-pentanoate





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