Paroxetine

This page contains recent news articles, when available, and an overview of Paroxetine but does not offer medical advice. You should contact your physician with regard to any health issues or concerns.


Overview:

Paroxetine
(when available)

Pharmacology and use:
Paroxetine, an antidepressant drug of the selective serotonin reuptake inhibitor (SSRI) type, has no active metabolites and has the highest specificity for serotonin receptors of all the SSRIs. It is used to treat depression resistant to other antidepressants, depression complicated by anxiety, panic disorder, social and general anxiety disorder, obsessive-compulsive disorder (OCD), premenstrual dysphoric disorder, premature ejaculation, and hot flashes of menopause in women with breast cancer. For the treatment of depression, depression accompanied by anxiety, obsessive compulsive disorder and panic attacks

Mechanism Of Action:
Paroxetine is a potent and highly selective inhibitor of neuronal serotonin reuptake. Paroxetine likely inhibits the reuptake of serotonin at the neuronal membrane, enhances serotonergic neurotransmission by reducing turnover of the neurotransmitter, therefore it prolongs its activity at synaptic receptor sites and potentiates 5-HT in the CNS; paroxetine is more potent than both sertraline and fluoxetine in its ability to inhibit 5-HT reuptake. Compared to the tricyclic antidepressants, SSRIs have dramatically decreased binding to histamine, acetylcholine, and norepinephrine receptors.

News Articles on Paroxetine

Limits to antidepressants' effectiveness: study  -  05 Jan 2010
Combining data from six studies that examined the effectiveness of two commonly prescribed antidepressants -- paroxetine and imipramine -- found the drugs ... Reuters

항우울제 효과, 매우 심ê°?한 환ìž?ì—?서만 나타나  -  05 Jan 2010
...펜실베니아 대학ì?˜ 로버트 드루베스 박사는 ì?¼ë°˜ì ?으로 ë§Žì?´ 사용ë?˜ëŠ” GSKì?˜ 'íŒ?실(Paxil, paroxetine)'ê³¼ ì?´ë¯¸í”„ë?¼ë¯¼(imipramine)ì—? 대한 효과를 조사한 6ê±´ì?˜ 연구를 ... 메디게이트뉴스

Study: Anti-Depressants May Alter Personality  -  ‎Jan 4, 2010‎
In this most recent study, 120 participants were randomly assigned to take the antidepressant paroxetine (Paxil and Seroxat), and, as in most trials of ... TIME (blog)

Lena Palaniyappan , Lisa Insole and Nicol Ferrier  -  ‎Jan 3, 2010‎
...[CrossRef][Medline] Bitsios P, Szabadi E, Bradshaw CM (1999) Comparison of the effects of venlafaxine, paroxetine and desipramine on the pupillary light ... Adv Psychiatric Treat (subscription)

Antidepressants and Suicide Risk: How Did Specific Information in FDA Safety ...  -  ‎Dec 31, 2009‎
Treatment recommendations pertained to the use of the antidepressants paroxetine and fluoxetine and to patient monitoring. Treatment patterns were expected ... Psychiatric Services (subscription)

Can a Change in Neuroticism Improve Depression? Part 1  -  ‎Dec 16, 2009‎
Now a study using the drug Paroxetine suggests that by controlling personality features or neuroticism, the symptoms of depression can be better controlled. ... EmpowHer (blog)

Report: GSK paid nearly $1 billion for Paxil suits  -  ‎Dec 14, 2009‎
...$200 million for addiction and birth-defect cases in lawsuits concerning the drug Paxil (paroxetine hydrochloride) since the drug's 1993 introduction. ... Drug Store News (blog)

Antidepressants May Change Personality for the Better  -  ‎Dec 10, 2009‎
Tang and his colleagues studied the effects of the SSRI paroxetine (Seroxat and Paxil) as compared to a placebo given in a trial that involved 240 adults ... HealthNews

No Word on Birth Defects in New SSRI Research  -  ‎Dec 26, 2009‎
Of these, 120 were assigned to take the SSRI paroxetine (Paxil) for 16 weeks. Another 60 received cognitive therapy for 16 weeks, and a further 60 were ... Lawyers and Settlements

Penn Collaboration Suggest Antidepressants May Change Personality, Leading To ...  -  ‎Dec 20, 2009‎
In this study, the advantage of paroxetine over placebo in changing personality appears far more drastic than its advantage over placebo in alleviating ... Medical News Today (press release)

Combining antidepressants: understanding drug interactions is the sine qua non  -  ‎Jan 3, 2010‎
Albers LJ, Reist C, Helmeste D, et al (1996) Paroxetine shifts imipramine metabolism. Psychiatry Research; 59: 189–96.[CrossRef][Medline] Bakish D, ... Adv Psychiatric Treat (subscription)

Comment on "Antidepressant Use and Risk of Incident Cardiovascular Morbidity ...  -  ‎Dec 14, 2009‎
A double-blind placebo-controlled pilot study of controlled-release paroxetine on depression and quality of life in chronic heart failure. ... Archives of Internal Medicine

Author(s): US Preventive Services Task Force.  -  ‎Dec 22, 2009‎
...(SSRIs) to increase suicidal behaviors in adults ages 18-29 years, particularly those with a major depressive disorder and those using paroxetine. ... Cardiosource

Sleep disorders: When going to bed is a nightmare  -  ‎Dec 14, 2009‎
Dr Idzikowski recommends paroxetine and clonazepam for adult sleep walkers – as well as cutting back on caffeine, cigarettes and alcohol, and going to bed ... Independent

Chemoinformatics: Where 'magic bullets' go astray  -  ‎Dec 11, 2009‎
Fluoxetine and paroxetine, both of which are selective serotonin reuptake inhibitors, were found to interact with -adrenergic receptors. ... Nature.com (subscription)

Tamoxifen, Endoxifen, and CYP2D6: The Rules for Evaluating a Predictive Factor  -  ‎Dec 17, 2009‎
...et al: Active tamoxifen metabolite plasma concentrations after coadministration of tamoxifen and the selective serotonin reuptake inhibitor paroxetine. ... Cancer Network

Women Turn to Natural Menopause Remedies for Safe, Effective Relief  -  ‎Dec 21, 2009‎
Noven Pharmaceuticals, Inc. (NASDAQ:NOVN) today announced positive top-line results from its Phase 2 clinical study evaluating Mesafemâ„¢ (low-dose paroxetine ... India Business Blog (blog)

Pharmacotherapy for borderline personality disorder: Cochrane systematic ...  -  ‎Dec 31, 2009‎
...lithium, oxcarbazepine), antidepressants (eg tranylcypromine, reboxetine, venlafaxine, duloxetine, sertraline, paroxetine, desipramine and imipramine), ... British Journal of Psychiatry

Brain serotonin-2 receptors in acute mania  -  ‎Dec 31, 2009‎
The effect of paroxetine on 5-HT2A receptors in depression. An [F-18]setoperone PET imaging study. Am J Psychiatry 2001; 158: 78 –85. ... British Journal of Psychiatry

Antidepresan Ubah Kepribadian  -  ‎Dec 10, 2009‎
Tim yang dikomandoi Tang itu menguji coba 240 pasien gangguan depresi berat yang diberi antara obat antidepresan SSRI bernama paroxetine dan placebo. ... Media Indonesia

Bu ilaçlar kiÅŸiliÄŸinizi deÄŸiÅŸtiriyor  -  ‎Dec 11, 2009‎
Araştırmacılar, önemli depresif bozukluğu olan 240 yetişkini 3 gruba ayırdı: 120'si paroxetine içti, 60'ı bilişsel tedavi gördü ve kalan 60 kişi ise yalancı ... Internet Haber

우울ì¦? 치료약물 '성격' 변화시킨다  -  ‎Dec 20, 2009‎
...연구결과 위약ì—? 비해 파로세틴(Paroxetine)ì?´ 우울ì¦? ì¦?ìƒ?ì?„ 줄ì?´ëŠ” 효과 보다 성격ì?„ 변화시키는 효과가 ë?” í?° 것으로 드러났다. 연구팀ì?€ "ì„ íƒ?절세로토닌재í?¡ìˆ˜ ... 메디컬투데이

å°?æ–¼é‡?度憂鬱症併用抗憂鬱藥物治療比單用Fluoxetine更有效  -  ‎Jan 3, 2010‎
...以å‰?的研究顯示,使用mirtazapineå’Œé?¸æ“‡æ€§è¡€æ¸…ç´ å†?å?¸æ”¶æŠ‘制劑(SSRI)paroxetine治療的MDD病患,改善程度優於使用單一種藥物。 本研究中,Blierå?šå£«ç­‰äººè©¦åœ–比較從治療 ... 臺灣新浪網

The Tangent - Down and Out in Paris and London  -  ‎Dec 17, 2009‎
Het tweede nummer 'Paroxetine – 20 mg' probeert je met wat gitaargeweld uit de winterdepressie te halen waardoor dit pilletje niet meer nodig is. ... Festivalinfo.nl

GlaxoSmithKline told to pay family $2.5m after jury finds paroxetine caused ...  -  ‎Oct 26, 2009‎
A Philadelphia jury has found that the antidepressant paroxetine (marketed as Paxil in the United States and Seroxat in the United Kingdom) caused heart ... cybermed.it

Antidepressants and depression may both harm a fetus  -  ‎Oct 21, 2009‎
While pregnant, Kilker's mother took the antidepressant paroxetine (Seroxat or Paxil), which belongs to the most commonly prescribed class of ... New Scientist

Are antidepressants affecting your sex drive?  -  ‎Nov 10, 2009‎
This class includes Prozac (fluoxetine), Zoloft (sertraline), Paxil (paroxetine) and others. SSRIs work by helping to restore the right balance of the brain ... KIVI-TV

Disciplinary panel puts sanctions on pharmacist who made errors  -  ‎Nov 12, 2009‎
Errors included dispensing 30mg instead of 20mg paroxetine tablets and supplying 15mg meloxicam tablets instead of 7.5mg. Mrs Hill said she had not been ... Chemist+Druggist

Mom's antidepressants tied to child health risks  -  ‎Nov 7, 2009‎
Most women on medication during pregnancy -- 71 percent -- used a selective serotonin reuptake inhibitor (SSRI) such as paroxetine (Paxil) or fluoxetine ... Tehran Times

Impact of the STAR*D Trial From the Perspective of the Payer  -  ‎Oct 30, 2009‎
Annals of Internal Medicine 132:743–756,2000[Abstract/Free Full Text] Kroenke K, West SL, Swindle R, et al: Similar effectiveness of paroxetine, fluoxetine, ... Psychiatric Services (subscription)

Which Antidepressants Treat Comorbid Anxiety and Depression?  -  ‎Oct 28, 2009‎
...[8] Antidepressants such as selective serotonin reuptake inhibitors (SSRIs) (eg, sertraline, paroxetine, fluoxetine, escitalopram), serotonin-norepinephrine ... Medscape

See the light if you feel SAD  -  ‎Oct 29, 2009‎
Antidepressant drugs such as fluoxetine, paroxetine and citalopram, collectively known as the SSRIs, act to increase levels of seretonin in the brain and so ... WalesOnline

BREAKING NEWS: Relenza helps GSK return to sales growth  -  ‎Oct 28, 2009‎
Turnover from the antidepressant Seroxat/Paxil (paroxetine) decreased 12% to £120 million. Vaccine sales slipped 2% to £802 million, and revenues from the ... Pharma Times

Mom's antidepressants tied to child health risks  -  ‎Nov 5, 2009‎
Most women on medication during pregnancy -- 71 percent -- used a selective serotonin reuptake inhibitor (SSRI) such as paroxetine (Paxil) or fluoxetine ... Reuters

항울제 'íŒ?실' 日서 ì‹ ìƒ?ì•„ 부작용 30ê±´  -  ‎Oct 21, 2009‎
...ì?¼ë³¸ì—?서 항우울제 'íŒ?실'(Paxil, paroxetine)ì?„ 투여받ì?€ 임산부ì—?서 태어난 ì‹ ìƒ?ì•„ì—? 선천성 ì?´ìƒ? 등 부작용ì?„ ì?¼ìœ¼í‚¨ 피해가 8ë…„ê°„ 약 30ê±´ì—? ì?´ë¥¸ 것으로 조사ë??다 ... 디지틀보사

Bijlmoordenares werd vaak mishandeld  -  ‎Nov 6, 2009‎
Toxicologische experts meldden de rechtbank dat paroxetine, het meest gebruikte middel tegen depressies, onafhankelijk van de dosering, vooral aan het begin ... De Telegraaf

Arts: pil leidde niet tot moord met bijl  -  ‎Nov 3, 2009‎
Paroxetine, dat in Nederland wordt verkocht als Seroxat, kan leiden tot agressief gedrag. Kort voor de moorden had de huisarts haar dit medicijn ... Volkskrant

Cruise, Tom (1962)  -  ‎Oct 30, 2009‎
Een controverse brak uit in 2005 nadat hij actrice Brooke Shields openlijk bekritiseerde voor het gebruik van het medicament Paxil (paroxetine), ... Gayworld.be

Drug suicide risk fears renewed  -  Aug 22, 2005
The drug Seroxat (paroxetine) is already banned from use by adolescents because of an ... Paroxetine is one in a class of drugs known as Selective Serotonin ... BBC News

US FDA, GlaxoSmithKline warn on Paxil suicide risk  -  May 14, 2006
...'Results of this analysis showed a higher frequency of suicidal behavior in young adults treated with paroxetine compared with placebo,' the FDA said in a ... Forbes

St John's wort may be effective anti-depressant  -  Feb 11, 2005
So to compare St John's wort to the widely-prescribed antidepressant paroxetine, Meinhard Kieser and his colleagues from Dr Willmar Schwabe Pharmaceuticals ... New Scientist

Doctors told not to prescribe Seroxat  -  Dec 11, 2005
A separate study revealed that use of paroxetine, rather than other ... The FDA noted that studies had only looked at the effects of paroxetine in the first ... Telegraph.co.uk

Antidepressants 'may harm sperm'  -  Sep 24, 2008
A small number of healthy men given the antidepressant paroxetine for four weeks had ... Paroxetine, sold as Seroxat or Paxil, is one of the most commonly ... BBC News

Common antidepressant does not increase birth defects  -  Jun 19, 2006
That stated that exposure to paroxetine, also known as Seroxat, ... Three abnormalities were reported after exposure to paroxetine: club feet after exposure ... New Scientist

Study Finds Antidepressant Use May Cause Male Infertility  -  Nov 11, 2008
Treatment with paroxetine (Paxil), which belongs to the selective serotonin reuptake ... Paroxetine was also associated with significant sexual dysfunction, ... FOXNews

… following in utero exposure to paroxetine, clonazepam and olanzapin...  -  Jan 19, 2007
We describe a full-term infant with failed respiratory effort and decerebrate posturing following in utero exposure to paroxetine. All signs and symptoms ... Nature.com

Changes to Warnings on Paroxetine  -  May 12, 2006
BETHESDA, MD -- May 12, 2006 -- GlaxoSmithKline and FDA notified healthcare professionals of changes to the Clinical Worsening and Suicide Risk subsection ... DG News

Older antidepressants work for Parkinson patients  -  Dec 18, 2008
The study found that paroxetine (brand name, Paxil), a so-called SSRI antidepressant, appears to be less effective than the "tricyclic" antidepressant ... Reuters India

The Brain: How The Brain Rewires Itself  -  Jan 19, 2007
Thirteen other patients received paroxetine (the generic form of the ... Paroxetine lowered activity there. As Toronto's Helen Mayberg explains, ... TIME

Anti-depressants pregnancy risk  -  Feb 4, 2005
Of these cases 64 were associated with Seroxat (paroxetine), 14 with Prozac ... The dose was only reported in 13 of the cases associated with paroxetine and ... BBC News

Pilot evaluation of selective serotonin reuptake inhibitor antidepress...  -  Jan 6, 2006
In this study, we evaluated the efficacy of paroxetine (selective serotonin ... 1 Loptinzi suggested that 12.5–37.5 mg/day of paroxetine is effective for ... Nature.com

Adult suicides linked to popular antidepressant  -  Aug 25, 2005
Patients taking paroxetine are more likely to attempt suicide than those taking a ... Paroxetine, which is sold as Seroxat and Paxil, belongs to a class of ... Nature.com

Effect of antidepressant warnings moderate-US study  -  Jan 7, 2008
L) antidepressant Paxil, known generically as paroxetine hydrochloride, for signs of worsening depression and suicidal thoughts. ... Reuters

Pharmac under fire over moves to phase out widely used antidepressant  -  Jan 19, 2007
But the move to phase out the Aropax brand of paroxetine in favour of generic ... For some patients transferring from their current form of paroxetine to ... New Zealand Herald

Paroxetine could harm babies  -  Sep 10, 2005
By Martin Johnston. The Ministry of Health is warning pregnant women who take a common anti-depressant to consult their doctors after the medicine was ... New Zealand Herald

Mylan begins selling generics of antidepressant  -  May 14, 2008
Because Mylan was the first company to file for approval to make a generic version of paroxetine extended-release, it is eligible for 180 days of market ... Boston Globe

Is paroxetine an effective treatment for hot flashes?  -  Nov 30, 2005
Stearns V et al. (2005) Paroxetine is an effective treatment for hot flashes: results from a prospective randomized clinical trial. ... Nature.com

CBT vs. paroxetine equally effective for hypochondriasis.(What's New...  -  May 1, 2007
To the authors' knowledge, this is the first report of a randomized, controlled trial comparing the efficacy of cognitive behavior therapy (CBT) with that ... Free with registration - Brown University Psychopharmacology... - AccessMyLibrary.com

Antipanic Efficacy of Paroxetine and Polymorphism within the Promoter...  -  Jul 20, 2005
Correspondence: Dr G Perna, Department of Neuropsychiatric Sciences, Anxiety Disorders Clinical and Research Unit, Istituto Scientifico HS Raffaele, ... Nature.com

SSRIs associated with severe violence in a small number of individuals  -  Sep 12, 2006
The sources used were data on paroxetine presented to the UK Committee on Safety of ... Of the SSRIs, paroxetine was primarily studied for two reasons. ... News-Medical.net

IN BRIEF/ HEALTHCARE; Glaxo May Have Shipped Inactive …  -  Oct 5, 2006
Glaxo doesn't know how many of the 7.5 million pills it voluntarily recalled last month were missing paroxetine hydrochloride, the active ingredient, ... Pay-Per-View - Los Angeles Times - ProQuest Archiver

Caraco OK'd on generic Paxil  -  Jul 3, 2007
The paroxetine hydrochloride tablet is indicated for a range of psychological disorders including major depressive disorder, panic disorder, ... United Press International

Paroxetine Decreases Social Anxiety–Related Drinking  -  Mar 12, 2008
March 12, 2008 (Savannah, Georgia) — In a trial of the selective serotonin reuptake inhibitor paroxetine (Paxil, GlaxoSmithKline) in individuals with both ... Medscape

Antidepressant Paxil possibly linked to birth defects  -  Sep 28, 2005
GlaxoSmithKline said it will include the results of the study in the product labeling of the drug, or paroxetine in generic form. ... 新�网

At the request of FDA, paroxetine's (Paxil, GlaxoSmithKline) pregnancy...  -  Jan 1, 2006
The change is the result of FDA findings that exposure to paroxetine during the first trimester of pregnancy may increase the risk of congenital ... Free with registration - Formulary - AccessMyLibrary.com

… Tentative FDA Approval for Paroxetine Hydrochloride Extended...  -  May 31, 2007
Mylan Announces Tentative FDA Approval for Paroxetine Hydrochloride Extended-Release Tablets. from PR Newswire. Highbeam Research – FREE Trial. Pay-Per-View - PR Newswire - HighBeam Research

JOURNAL WATCH: St John's wort matches paroxetine  -  Feb 19, 2005
An extract of St John's wort is at least as effective in treating depression as paroxetine, a German study concludes. The randomised, double-blind trial ... Pay-Per-View - Pulse - Factiva, from Dow Jones

Quetiapine bests paroxetine in bipolar trial.(Adult Psychiatry)(Clinic...  -  Oct 1, 2008
Quetiapine bests paroxetine in bipolar trial.(Adult Psychiatry)(Clinical report) ... find Clinical Psychiatry News articles. Pay-Per-View - Clinical Psychiatry News - HighBeam Research

FDA advisory on paroxetine.(Food and Drug Administration)  -  Mar 15, 2006
Multiple studies over the past decade have been supportive of the reproductive safety of the selective serotonin reuptake inhibitors (SSRIs) when used ... Free with registration - Internal Medicine News - AccessMyLibrary.com

… paroxetine for PMDD.(What's New in Research: Focus on Paroxetine)(...  -  Apr 1, 2007
The authors of this Swedish study write that numerous controlled trials have demonstrated serotonin reuptake inhibitors (SRIs) to be effective in treating ... Free with registration - Brown University Psychopharmacology... - AccessMyLibrary.com

Increased suicide risk linked to antidepressants  -  Aug 23, 2005
The studies included 916 patients on paroxetine and 550 on placebos. ... "Paroxetine is an important medicine designed to treat serious psychiatric diseases ... The Age

The FDA advisory on paroxetine.(DRUGS, PREGNANCY, AND …  -  Jan 15, 2006
Multiple studies over the past decade have been supportive of the reproductive safety of the selective serotonin reuptake inhibitors (SSRIs) when used ... Free with registration - OB GYN News - AccessMyLibrary.com

Depression not a normal part of aging  -  Jun 1, 2007
...treatment with the antidepressant paroxetine and interpersonal psychotherapy, or to those who responded to the initial treatment but quickly relapsed, ... United Press International

AMA Urges Paroxetine Users To Consult Their Doctors  -  Sep 7, 2005
By Australian Medical Association (AMA), Sep 7, 2005 - 11:52:00 PM. The AMA(australia) is today alerting its members of a decision by pharmaceutical company ... RxPG NEWS

… and Tolerability of Escitalopram Over Paroxetine in Long-Term...  -  Sep 2, 2008
A total of 383 patients received at least 1 dose of paroxetine 20 mg QD for the first week, with the first dose increased to 40 mg after 1 week. ... DG News

ACOG advises against paroxetine in pregnancy.(Women's Health)(The …  -  Jan 15, 2007
The American College of Obstetricians and Gynecologists is advising physicians to avoid prescribing the antidepressant paroxetine (Paxil) to pregnant women ... $4.95 - Internal Medicine News - ECNext

Trial tests maintenance paroxetine and psychotherapy in elderly...  -  Jun 1, 2006
Without adequate treatment, depression in older people can trigger "a downward spiral of disability, depression, and suffering," Charles F. Reynolds III, ... Free with registration - Brown University Psychopharmacology... - AccessMyLibrary.com

Medical board charges Hickory doctor.  -  May 2, 2007
The notice of charges says that Greer prescribed for himself Ambien, a sleep aid, paroxetine, an antidepressant, prednisone, an anti-inflammatory steroid, ... Free with registration - Charlotte Observer - AccessMyLibrary.com

Antidepressant Paroxetine Shown to Increase Suicidal Tendencies in …  -  Aug 22, 2005
By BioMed Central, Adult patients taking the antidepressant drug paroxetine are at higher risk of attempting to commit suicide than those not taking ... RxPG NEWS

Paroxetine effective as post-hormone therapy treatment  -  Feb 13, 2008
Following menopausal hormone cessation, paroxetine (Paxil, GlaxoSmithKline) controlled release may be an effective option for perimenopausal and ... Endocrine Today

FDA strengthens label warning on paroxetine; riskier pregnancy...  -  Jan 1, 2006
FDA strengthens label warning on paroxetine; riskier pregnancy category.(News) ... find Family Practice News articles. The Food and Drug Administration has ... Pay-Per-View - Family Practice News - HighBeam Research

… Interaction Observed Between Paroxetine and Investigational...  -  Sep 12, 2007
By Ed Susman. SAN FRANCISCO, CA -- September 12, 2007 -- Researchers observed no drug-drug interactions between the selective serotonin reuptake inhibitor ... DG News

… Release: Mylan Launches Paroxetine Hydrochloride Extended-Release ...  -  May 14, 2008
Mylan Launches Paroxetine Hydrochloride Extended-Release Tablets. from PR Newswire. Highbeam Research – FREE Trial. Pay-Per-View - PR Newswire - HighBeam Research

Paroxetine (Systemic).  -  Oct 27, 2005
Paroxetine (pa-ROX-uh-teen) is used to treat mental depression, obsessive-compulsive disorder, panic disorder, generalized anxiety disorder, social anxiety ... Free with registration - USP DI-Volume II, Advice for the... - AccessMyLibrary.com

Risk Of Violent Behavior With Selective Serotonin Reuptake Inhibitors...  -  Sep 14, 2006
The sources used were data on paroxetine presented to the UK Committee on Safety of ... Of the SSRIs, paroxetine was primarily studied for two reasons. ... Medical News Today - Medical News Today (press release)

Abstract and Introduction  -  May 31, 2007
Results: Controlled-release paroxetine resulted in significantly more recovery ... Controlled-release paroxetine was associated with higher general health ... Medscape

St. John's Wort at Least as Effective as Paroxetine in the Treatment...  -  Feb 13, 2005
According to latest research, Dr. Willmar Schwabe Pharmaceuticals' proprietary St. John's Wort extract WS® 5570 is at least as effective and better ... i-newswire.com

Mylan Launches Paroxetine Hydrochloride Extended-Release Tablets  -  May 15, 2008
Mylan Pharmaceuticals has launched Paroxetine Hydrochloride (HCl) Extended-release (ER) Tablets, the generic version of GlaxoSmithKline's (GSK) Paxil CR. ... emaxhealth.com

The FDA advisory on paroxetine.(DRUGS, PREGNANCY, AND …  -  Jan 15, 2006
The FDA advisory on paroxetine.(DRUGS, PREGNANCY, AND LACTATION) ... find OB GYN News articles. Multiple studies over the past decade have been supportive ... Pay-Per-View - OB GYN News - HighBeam Research

Use of sertraline, paroxetine and fluvoxamine by nursing women  -  May 1, 2005
Declaration of interest This study was supported by the National Institute of Mental Health, Smith Kline Beecham and Pfizer. ... British Journal of Psychiatry (subscript...

Plant extract better for depression: Rediff.com India News  -  Feb 16, 2005
Participants who took paroxetine suffered more side-effects, with 269 adverse effects being reported over the treatment period, while those taking St John's ... Rediff

… With Anxiety Disorders Treated With Paroxetine: Presented at ADAA  -  Apr 3, 2007
The investigators found no significant differences between paroxetine and placebo ... Likewise, there was no significant difference between paroxetine and ... DG News

Article: The FDA advisory on paroxetine.(Drugs, Pregnancy, And …  -  Feb 1, 2006
The FDA advisory on paroxetine.(Drugs, Pregnancy, And Lactation) ... find Family Practice News articles. Multiple studies over the past decade have been ... Pay-Per-View - Family Practice News - HighBeam Research

Withdrawal Symptoms From Paroxetine May Last For A Long Time  -  Jan 17, 2008
When withdrawal symptoms ensue after discontinuation of a drug, such as paroxetine, it is generally assumed they will last for a few weeks and then they ... Medical News Today - Medical News Today (press release)

… standardized hyperforin content equivalent to paroxetine for...  -  Jun 1, 2005
More adverse events (AEs) were experienced in the paroxetine group than the ... The risk of AEs was 1.72 times greater in the paroxetine group than in the ... $4.95 - Original Internist - ECNext

Paroxetine Exposure in Early Pregnancy Linked to Risk of Defects  -  Dec 8, 2005
Dec. 8, 2005 — The US Food and Drug Administration (FDA) has warned healthcare professionals that exposure to paroxetine during the first trimester of ... Medscape

Study links Paxil to higher number of birth defects .  -  Oct 3, 2005
The drug, which goes by the generic name paroxetine, is al ready classified as a category drug for pregnant women —meaning comprehensive studies of its ... Milwaukee Journal Sentinel - Google News Archive

Paroxetine plus psychotherapy for major depression in the elderly.(Wha...  -  May 1, 2006
In a 2-year randomized, double-blind, placebo-controlled maintenance trial of elderly patients, who had fully or partially recovered from major depressive ... Free with registration - Brown University Geriatric Psychopharmac... - AccessMyLibrary.com

Triiodothyronine Addition to Paroxetine in the Treatment of Major …  -  Feb 20, 2008
Bente C. Appelhof 1 , Jantien P. Brouwer 1 , Richard van Dyck, Eric Fliers, Witte JG Hoogendijk, Jochanan Huyser, Aart H. Schene, Jan GP Tijssen and Wilmar ... Journal of Clinical Endocrinology and...

… Announces Settlement of Paroxetine Hydrochloride Extended-Release ...  -  Oct 23, 2007
PITTSBURGH, Oct. 23 /PRNewswire-FirstCall/ -- Mylan Inc. today announced that it and its subsidiary Mylan Pharmaceuticals Inc. have entered into a patent ... Free with registration - PR Newswire - AccessMyLibrary.com

Paxil label to warn of suicide risk in adults.(Paroxetine)(Drug...  -  Jun 15, 2006
Paroxetine may increase the risk of suicidal behavior in adults, particularly in young adults, findings from a recent metaanalysis suggest. ... Free with registration - Internal Medicine News - AccessMyLibrary.com

St. John's Wort vs. Paroxetine in Moderate to Severe Depression  -  Jul 1, 2005
Clinical Question: In adults with moderate to severe major depression, is an extract of St. John's wort as effective as paroxetine (Paxil) in the short term ... AAFP News Now

Paroxetine in pregnancy warning issued.(Brief Article)  -  Dec 17, 2005
The Medicines and Healthcare products Regulatory Agency has written to health professionals following concerns over the safety of paroxetine during ... $4.95 - Chemist & Druggist - ECNext

Paxil may raise birth defect risk, Health Canada warns  -  Oct 11, 2005
Patients should not stop taking paroxetine, the drug's generic name, without first checking with their doctor, because of the risk of symptoms when ... CBC.ca

Urticarial vasculitis secondary to paroxetine.(CASE REPORTS)  -  Nov 1, 2006
Paroxetine (Paxil) is a widely prescribed antidepressant of the selective ... This case represents the first reported incidence of paroxetine-induced ... Free with registration - Journal of Drugs in Dermatology - AccessMyLibrary.com

Paroxetine: first trimester exposure and congenital malformations.(Saf...  -  Sep 22, 2005
Canada -- The manufacturer of paroxetine (Paxil[R]) has informed health care professionals of important new safety information regarding use during the ... Free with registration - WHO Drug Information - AccessMyLibrary.com

Venlafaxine (Effexor XR) and Paroxetine Effective for Short-Term …  -  Nov 10, 2005
By Steve Pridgeon. VANCOUVER, CANADA -- November 10, 2005 -- Venlafaxine (Effexor XR) and paroxetine are effective in the short-term treatment of panic ... DG News

Multiple Doses of Paroxetine Safe and Well Tolerated in Children and ...  -  Nov 14, 2005
By Paula Moyer. TORONTO, CANADA -- November 14, 2005 -- Children and adolescents appear to tolerate paroxetine (Paxil) well, whether they have major ... DG News

FDA advisory on paroxetine.(Food and Drug Administration) | Article...  -  Mar 15, 2006
FDA advisory on paroxetine.(Food and Drug Administration) ... find Internal Medicine News articles. Multiple studies over the past decade have been ... Pay-Per-View - Internal Medicine News - HighBeam Research

Paroxetine May Increase Risk for Congenital Malformations  -  Feb 14, 2006
By Cuzzell, Janice Zeigler. On December 8, 2005, the Food and Drag Administration (FDA) issued a public health advisory for paroxetine hydrochloride (PaxiP, ... RedOrbit

Paroxetine (Paxil) and congenital malformations.  -  Nov 22, 2005
Reason for posting: Selective serotonin reuptake inhibitors (SSRIs) have not previously been demonstrated, as a group, to be teratogenic. ... Free with registration - CMAJ: Canadian Medical Association... - AccessMyLibrary.com

GSK Changes Paroxetine Prescribing Information  -  Dec 12, 2005
GlaxoSmithKline (NYSE: GSK) has changed the Paxil® (paroxetine hydrochloride) labeling to reflect updated epidemiological studies which show that infants ... Medical News Today - Medical News Today (press release)

QOL in Depressed Patients with Type 2 Diabetes Treated with Paroxetine...  -  Jun 15, 2007
The aim of this investigator-initiated trial was to evaluate the effect of the antidepressant paroxetine on quality of life, metabolic control, ... Medscape

FDA Warnings Affected Prescriptions Of Antidepressants To Youth  -  Jan 10, 2008
..."After the FDA first recommended not treating youth with paroxetine, there was a significant absolute decline in paroxetine use by youth but not significant ... sciencedaily.com

Depressed Elderly May Benefit From 2 Years of Maintenance...  -  Mar 15, 2006
This study evaluated the efficacy of maintenance paroxetine and monthly ... GlaxoSmithKline provided paroxetine tablets. Two authors have disclosed various ... Medscape

… secondary to risperidone and paroxetine.(Adverse Events)(Clinical...  -  Sep 1, 2006
Hypothermia is a condition in which the core body temperature falls below 35[degrees]C. While commonly caused by accidental cold exposure, it can also be ... Free with registration - Brown University Geriatric Psychopharmac... - AccessMyLibrary.com

Paroxetine treats premenstrual mood disorder  -  Aug 31, 2005
By David Douglas. NEW YORK (Reuters Health) - Intermittent dosing of controlled release paroxetine (Paxil-CR) is successful for the treatment of ... RedOrbit

Paroxetine: possible risk of teratogenicity.(Safety and Efficacy...  -  Jan 1, 2006
Singapore -- The manufacturer of paroxetine has notified healthcare professionals of preliminary findings of a retrospective epidemiological study which ... Free with registration - WHO Drug Information - AccessMyLibrary.com

New data on paroxetine-suicide link.(Brief article)  -  May 11, 2006
A new analysis by GlaxoSmith-Kline of its data on paroxetine has shown increased risks of suicidal behaviour are mainly restricted to young adults. ... Free with registration - Pulse - AccessMyLibrary.com

Paroxetine (Paxil) and congenital malformations  -  Jun 28, 2007
Reason for posting: Selective serotonin reuptake inhibitors (SSRIs) have not previously been demonstrated, as a group, to be teratogenic. ... CMAJ

Paroxetine exposure may not raise birth defect risk.(News) | Article...  -  Jul 15, 2006
Paroxetine exposure may not raise birth defect risk.(News) ... find OB GYN News articles. PRAGUE -- Despite last year's warnings from the US Food and Drug ... Pay-Per-View - OB GYN News - HighBeam Research

Paroxetine HCl Oral: Dosage, Uses and Warnings  -  Oct 24, 2007
This information is generalized and not intended as specific medical advice. Consult your healthcare professional before taking or discontinuing any drug or ... Medscape

… standardized hyperforin content equivalent to paroxetine for...  -  Jun 1, 2005
St. John's Wort extract with standardized hyperforin content equivalent to paroxetine for treatment of moderate to severe depression. Pay-Per-View - Original Internist - HighBeam Research

GSK revises pregnancy/precautions section for paroxetine.( …  -  Oct 10, 2005
The study results suggest an increase in the risk of overall major congenital malformations for paroxetine as compared with other antidepressants. ... Free with registration - Drug Topics - AccessMyLibrary.com

… Tentative FDA Approval for Paroxetine Hydrochloride Extended...  -  Jun 4, 2007
Paroxetine Hydrochloride Extended-release Tablets are the generic version of GlaxoSmithKline's Paxil CR(R). Paroxetine Hydrochloride Extended-release ... Compliance Home - Compliance Home

SSRIs and deliberate self-harm * Response from Pfizer * Response from...  -  Jul 8, 2006
Similarly, in the paroxetine trial programme reported by Khan et al, ... With respect to paroxetine, Dr Healy misstates the scope of the Khan et al ... British Journal of Psychiatry (subscript...

Few options other than hormone therapy work  -  May 12, 2006
Published last week in the Journal of the American Medical Association, it found that antidepressants such as fluoxetine (Prozac) and paroxetine (Paxil) ... Pay-Per-View - The Record - ProQuest Archiver

Case Note: Synthon BV v SmithKline Beecham plc, House of Lords.  -  Nov 8, 2005
This is a form of the well-known compound paroxetine used to treat depression and related disorders which had been marketed in the form of its hydrochloride ... $4.95 - Mondaq Business Briefing - ECNext

Article: Maternal paroxetine unrelated to cardiac malformations.(Adult...  -  Sep 1, 2008
Maternal paroxetine unrelated to cardiac malformations.(Adult Psychiatry) ... find Clinical Psychiatry News articles. MONTEREY, CALIF. Pay-Per-View - Clinical Psychiatry News - HighBeam Research

Article: Paroxetine in pregnancy okay.(exposure to paroxetine results...  -  Aug 15, 2006
Paroxetine in pregnancy okay.(exposure to paroxetine results in congenital anomalies of fetus ) ... find Family Practice News articles. Pay-Per-View - Family Practice News - HighBeam Research

Cadila Healthcare receives USFDA approval for Paroxetine  -  Mar 12, 2007
Cadila Healthcare said that it received approval from the USFDA to market Paroxetine tablets in different strengths of 10 mg, 20 mg, 30 mg and 40 mg. ... Myiris.com

… Announces Settlement of Paroxetine Hydrochloride Extended-Release ...  -  Oct 23, 2007
Mylan Announces Settlement of Paroxetine Hydrochloride Extended-Release Tablets with GlaxoSmithKline. from PR Newswire. Highbeam Research – FREE Trial. Pay-Per-View - PR Newswire - HighBeam Research

Paroxetine may increase risk for congenital malformations.  -  Feb 1, 2006
On December 8, 2005, the Food and Drug Administration (FDA) issued a public health advisory for paroxetine hydrochloride (Paxil[R], Paxil CR[R]). ... $4.95 - Dermatology Nursing - ECNext

Anti-depressants used during pregnancy linked to neonatal withdrawal ...  -  Feb 6, 2005
Of these cases 64 were associated with paroxetine, 14 with fluoxetine, ... The dose was only reported in 13 cases associated with paroxetine and ranged from ... i-newswire.com

Concert Pharmaceuticals Presents Preclinical Results Supporting Co- …  -  Sep 25, 2008
Studies have shown paroxetine is effective in the treatment of VMS. However, recent reports suggest that co-administration of paroxetine with tamoxifen may ... Genetic Engineering News - Genetic Engineering News (press release)

Article: Paroxetine tied to sperm DNA fragmentation.(Mental Health)  -  Dec 1, 2008
Use of paroxetine (Paxil) appears to put healthy men at greater risk of sperm DNA fragmentation, according to data from a small study. ... Pay-Per-View - Family Practice News - HighBeam Research

… 3A and 3B receptor genes on nausea induced by paroxetine  -  Mar 14, 2006
Blood samples were collected from 78 individuals after at least 2 weeks treatment with the same daily dose of paroxetine. The patients visited every 2 weeks ... Nature.com

IN BRIEF: Seroxat (paroxetine).(Brief article)  -  Mar 10, 2007
Seroxat (paroxetine) is now also supplied in a 10mg dose; the tablets are round, pale pink and coated. The white 20mg and blue 30mg tablets, ... Free with registration - Chemist & Druggist - AccessMyLibrary.com

Brand Names/Synonyms:
Paroxetine is also known by the following brand names and/or synonymsAropax; FG 7051; Paroxetina [Inn-Spanish]; Paroxetine; Paroxetine Hcl; Paroxetine [Usan:Ban:Inn]; Paroxetinum [Inn-Latin]; Paxil; Paxil Cr; Pexeva; Seroxat

Drug Category:
Paroxetine is categorized under the following by the FDA: Antidepressants; Selective Serotonin Reuptake Inhibitors (SSRIs); ATC:N06AB05

Dosage Forms:
Tablet

Absorption:
completely absorbed after oral dosing

Interactions:
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Chemical IUPAC Name:
3-(benzo[1,3]dioxol-5-yloxymethyl)-4-(4-fluorophenyl)-piperidine





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