Peginterferon alfa-2b

This page contains recent news articles, when available, and an overview of Peginterferon alfa-2b but does not offer medical advice. You should contact your physician with regard to any health issues or concerns.


Overview:

Peginterferon alfa-2b
(when available)

Pharmacology and use:
Upregulates the expression of MHC I proteins, allowing for increased presentation of peptides derived from viral antigens. This enhances the activation of CD8+ T cells that are the precursors for cytotoxic T lymphocytes (CTLs) and makes the macrophage a better target for CTL-mediated killing. Interferon alpha also induce the synthesis of several key antiviral mediators, including 2'-5' oligoadenylate synthetase (2'-5' A synthetase) and protein kinase R. For treatment of hairy cell leukemia, malignant melanoma, and AIDS-related Kaposi's sarcoma

Mechanism Of Action:
Interferon alpha binds to type I interferon receptors (IFNAR1 and IFNAR2c) which, upon dimerization, activate two Jak (Janus kinase) tyrosine kinases (Jak1 and Tyk2). These transphosphorylate themselves and phosphorylate the receptors. The phosphorylated INFAR receptors then bind to Stat1 and Stat2 (signal transducers and activators of transcription)which dimerize and activate multiple (~100) immunomodulatory and antiviral proteins. Interferon alpha binds less stably to type I interferon receptors than interferon beta.

News Articles on Peginterferon alfa-2b

SILENCE THERAPEUTICS PLC - Acquisition  -  ‎Dec 16, 2009‎
...oncology therapeutics including Doxil(R) (doxorubicin HCL liposome injection), PegIntron(R) (Peginterferon alfa-2b) and Vectibix(R) (panitumumab). ... Trading Markets (press release)

Schering-Plough Reports Potent Antiviral Activity With Narlaprevir (SCH 900518 ...  -  ‎Nov 2, 2009‎
Once-Daily Narlaprevir (SCH 900518) in Combination with Peginterferon alfa-2b/Ribavirin for Treatment-Naive Patients with Genotype-1 Chronic Hepatitis C: ... Reuters

Results from two Canadian studies confirm sustained viral response rates seen ...  -  ‎Nov 2, 2009‎
...consistent with the 40 per cent SVR attained with approved peginterferon alfa-2B/ribavirin (PEGETRON) therapy in the recent United States-based IDEAL ... Canada NewsWire (press release)

Successful Treatment with Peginterferon alfa-2b of HBeAg-positive HBV...  -  Mar 2, 2006
Correspondence: Harry LA Janssen, MD, PhD, Department of Gastroenterology and Hepatology, Erasmus Medical Center, Dr. Molewaterplein 40, Room Ca 326, ... Nature.com

Roche presents favorable data on hepatitis drug Pegasys  -  Apr 28, 2008
By Zurich Bureau. ZURICH (MarketWatch) -- Swiss drug company Roche Holding AG (NQB:RHHB.Y) said Monday studies of its hepatitis treatment Pegasys shows it ... MarketWatch

Learn about Peginterferon alfa-2b from Consumer Reports Health.  -  Jan 7, 2005
Peginterferon alfa-2b may cause or worsen the following conditions that may be serious or cause ... Full Alert. Peginterferon alfa-2b is used alone or in ... consumerreports.org

Hepatitis C therapy peginterferon alfa-2b shows promise  -  Apr 24, 2008
The hepatitis C therapy peginterferon alfa-2b, when given as low-dose maintenance therapy, can prevent disease progression in certain patients who failed ... News-Medical.net

Peginterferon alfa-2b produced sustained responses in patients with …  -  Jan 7, 2005
Results from a large international clinical study reported in this week's issue of The Lancet showed that peginterferon alfa-2b produced sustained responses ... News-Medical.net

Examining Gene Expression, Drug Compounds And Liver …  -  May 20, 2007
Hepatitis C not only affects more than 3.9 million Americans, but continues to impact and influence the occurrence of related inflammatory conditions. ... Medical News Today - Medical News Today (press release)

Long-Term Pegylated Interferon Alfa-2b Therapy in Stage III Melanoma ...  -  Jul 11, 2008
KENILWORTH, NJ, July 11 /PRNewswire-FirstCall/ -- Today, Schering-Plough and the EORTC announced that long-term treatment with pegylated interferon alfa-2b ... RedOrbit

How to take Peginterferon alfa-2b from Consumer Reports Health.  -  Jan 7, 2005
Peginterferon alfa-2b may cause or worsen the following conditions that may be serious or cause ... Full Alert. tell your doctor and pharmacist if you are ... consumerreports.org

Results of Peginterferon Alfa-2b and Ribavirin Study in Retreating …  -  Oct 30, 2006
BOSTON, MA -- October 30, 2006 -- Schering-Plough today reported data from EPIC3, a large ongoing clinical study, showing that retreatment with ... DG News

PegIntron(R) (peginterferon alfa-2b) Clinical Studies in Hepatitis to...  -  Apr 7, 2005
Schering-Plough's PegIntron(R) (peginterferon alfa-2b), used in combination therapy with Rebetol(R) (ribavirin), is proven effective in treating patients ... Free with registration - PR Newswire Europe - AccessMyLibrary.com

… Review for Schering-Plough's Peginterferon Alfa-2b for the...  -  Jan 31, 2008
FDA Grants Priority Review for Schering-Plough's Peginterferon Alfa-2b for the Adjuvant Treatment of Patients With Stage III Melanoma. from PR Newswire. Pay-Per-View - PR Newswire - HighBeam Research

PegInterferon-alfa-2b with Ribavirin Shows Promise  -  May 3, 2005
By American Association for the Study of Liver Diseases (AASLD), [RxPG] More than half of 61 children infected with chronic hepatitis C achieved a sustained ... RxPG NEWS

Press Release: Human Genome Sciences Announces Full Presentation …  -  Nov 5, 2007
Human Genome Sciences Announces Full Presentation of Quality-of-Life Results From Phase 2b Trial of Albuferon(R) for Hepatitis C. from PR Newswire. Pay-Per-View - PR Newswire - HighBeam Research

peginterferon alfa-2b Schering Plough clinical data (hepatitis C).  -  Dec 11, 2006
On 27 October 2006 Shering-Plough reported further data from EPIC3, a large multicenter clinical study in chronic HCV patients who failed previous ... Pay-Per-View - R & D Focus Drug News - Factiva, from Dow Jones

… First Study Showing Peginterferon Alfa-2b Effective as Monotherapy...  -  Jan 7, 2005
The Lancet Publishes First Study Showing Peginterferon Alfa-2b Effective as Monotherapy in the Treatment of Chronic Hepatitis B. ... find PR Newswire Europe ... Pay-Per-View - PR Newswire Europe - HighBeam Research

Schering-Plough Highlights PEGINTRON(TM) Clinical Data Presentations …  -  Oct 30, 2007
KENILWORTH, NJ, Oct. 30 /PRNewswire-FirstCall/ -- Leading researchers will present 68 data presentations involving Schering-Plough's hepatitis products, ... RedOrbit

Press Release: New Data from Largest US Hepatitis C Trial Provide …  -  Oct 30, 2006
New Data from Largest US Hepatitis C Trial Provide Insights Into Optimizing Treatment for Patient Populations Traditionally Considered Difficult to Treat. Pay-Per-View - PR Newswire - HighBeam Research

… Review for Schering-Plough's Peginterferon Alfa-2b for the...  -  Feb 1, 2008
FDA Grants Priority Review for Schering-Plough's Peginterferon Alfa-2b for the Adjuvant Treatment of Patients With Stage III Melanoma. ... find BIOTECH ... Pay-Per-View - BIOTECH Patent News - HighBeam Research

… B Therapy; Study shows peginterferon alfa-2b effective monotherapy...  -  Feb 8, 2005
2005 FEB 8 - (NewsRx.com & NewsRx.net) -- Results from a large international clinical study reported in The Lancet showed that peginterferon alfa-2b ... Pay-Per-View - Science Letter - Factiva, from Dow Jones

Press Release: Human Genome Sciences Announces Presentation at …  -  Nov 5, 2007
Human Genome Sciences Announces Presentation at AASLD of Results of Phase 2b Trial of Albuferon(R) for Chronic Hepatitis C. from PR Newswire. Pay-Per-View - PR Newswire - HighBeam Research

Customizing treatment to patient populations  -  Aug 10, 2006
Combination treatment with pegylated interferon plus ribavirin is the most effective therapy for patients with chronic hepatitis C virus (HCV); however, ... Nature.com

Press Release: Three Studies Presented at 43rd EASL Showed Higher …  -  Apr 26, 2008
Three Studies Presented at 43rd EASL Showed Higher SVR for PEGASYS(R) (Peginterferon Alfa-2a) Plus Ribavirin Than Peginterferon Alfa-2b Plus Ribavirin in ... Pay-Per-View - PR Newswire - HighBeam Research

… Center; Study shows peginterferon alfa-2b effective monotherapy...  -  Feb 9, 2005
2005 FEB 9 - (NewsRx.com & NewsRx.net) -- Results from a large international clinical study reported in The Lancet showed that peginterferon alfa-2b ... Pay-Per-View - Biotech Week - Factiva, from Dow Jones

Similar Efficacy Shown For Pegylated Interferon Alfa-2b, Pegylated …  -  Nov 7, 2007
By Maria Bishop. BOSTON, MA -- November 7, 2007 -- There is no difference in sustained viral response (SVR) rates between patients with hepatitis C virus ... DG News

… B Therapy; Study shows peginterferon alfa-2b effective monotherapy...  -  Feb 12, 2005
2005 FEB 12 - (NewsRx.com & NewsRx.net) -- Results from a large international clinical study reported in The Lancet showed that peginterferon alfa-2b ... Pay-Per-View - Obesity, Fitness & Wellness Week - Factiva, from Dow Jones

Press Release: MIGENIX Receives Approval for MX-3253 Phase II …  -  May 16, 2006
Article: Peginterferon alfa-2b (PegIntron) has to be given ... PR Newswire; July 28, 2003 ; 700+ words ... ... prescribed once weekly dosing schedule of ... Pay-Per-View - PR Newswire - HighBeam Research

Press Release: Three Studies Presented at 43rd EASL Strongly Indicate...  -  Apr 26, 2008
Three Studies Presented at 43rd EASL Strongly Indicate Better Efficacy for PEGASYS in Curing Hepatitis C.(Clinical report) from PR Newswire Europe. Pay-Per-View - PR Newswire Europe - HighBeam Research

Press Release: Roche Driving PROGRESS in Treatment of Difficult-to- …  -  Mar 14, 2007
Roche Driving PROGRESS in Treatment of Difficult-to-Cure Hepatitis C Patients With New PEGASYS (R) (peginterferon alfa-2a (40KD)) and COPEGUS(R) (ribavirin) ... Pay-Per-View - PR Newswire Europe - HighBeam Research

PegIntron(R) (peginterferon alfa-2b) Clinical Studies in Hepatitis to...  -  Apr 7, 2005
PegIntron(R) (peginterferon alfa-2b) Clinical Studies in Hepatitis to be Presented at 40th Annual Meeting of the European Association for the Study of the ... Pay-Per-View - PR Newswire Europe - HighBeam Research

Press Release: MIGENIX Reports First Quarter Fiscal Year 2007...  -  Sep 15, 2006
MIGENIX Reports First Quarter Fiscal Year 2007 Financial Results. from PR Newswire. Highbeam Research – FREE Trial. Pay-Per-View - PR Newswire - HighBeam Research

… labeling changes for peginterferon alfa-2b (PegIntron, Schering...  -  May 1, 2008
FDA approved labeling changes for peginterferon alfa-2b (PegIntron, Schering-Plough) and ribavirin (Rebetul, Schering-Plough) as combination therapy for the ... $9.94 - Formulary - Alacra Store

Press Release: Schering-Plough Highlights PEGINTRON(TM) Clinical …  -  Oct 30, 2007
Schering-Plough Highlights PEGINTRON(TM) Clinical Data Presentations at the American Association for the Study of Liver Diseases (AASLD) 2007 Annual ... Pay-Per-View - PR Newswire - HighBeam Research

Press Release: MIGENIX Completes Enrollment of Celgosivir (MX-3253) …  -  Jun 15, 2006
MIGENIX Completes Enrollment of Celgosivir (MX-3253) Phase IIb HCV Combination Study. from PR Newswire. Highbeam Research – FREE Trial. Pay-Per-View - PR Newswire - HighBeam Research

Press Release: Potential New Oral Treatment May Revolutionise …  -  Apr 26, 2008
Potential New Oral Treatment May Revolutionise Management of Deadly Hepatitis C Virus. from PR Newswire Europe. Highbeam Research – FREE Trial. Pay-Per-View - PR Newswire Europe - HighBeam Research

… Shows 12 Weeks of Peginterferon Alfa-2b and Ribavirin Combination ...  -  Jun 22, 2005
SAN GIOVANNI ROTONDO, Italy, June 22 /PRNewswire-FirstCall/ -- Results of a new study published in the current issue of the New England Journal of Medicine ... $4.95 - PR Newswire - ECNext

International Approvals: DCVax-Brain, PegIntron/Rebetol, Revlimid  -  Jul 16, 2007
July 16, 2007 — The Swiss Institute of Public Health has approved the world's first brain cancer vaccine. The European Commission (EC) has approved an ... Medscape

Press Release: Customising Treatment With PEGASYS(R) Plus …  -  Oct 27, 2006
Customising Treatment With PEGASYS(R) Plus COPEGUS(R) Improves Chances for Cure in Hepatitis C.(Clinical report) from PR Newswire Europe. Pay-Per-View - PR Newswire Europe - HighBeam Research

Hepatitis C Therapy; Peginterferon alfa-2b benefits patients diagnosed...  -  Apr 30, 2005
2005 APR 30 - (NewsRx.com) -- Peginterferon alfa-2b benefits patients diagnosed with acute hepatitis C. According to a study from Italy, "acute hepatitis C ... Pay-Per-View - Obesity, Fitness & Wellness Week - Factiva, from Dow Jones

Press Release: European Commission Approval of New Indication for …  -  Dec 4, 2008
European Commission Approval of New Indication for Roche's Pegasys(R) (peginterferon alfa-2a) Offers Hepatitis C Patients a Second Chance for a Cure. from ... Pay-Per-View - PR Newswire Europe - HighBeam Research

Early and Accurate Prediction of Peg-IFNs/Ribavirin Therapy Outcome...  -  Oct 25, 2007
A novel biomathematical model that analyzes the combined alanine transaminase (ALT) and viral-load kinetics during the first month of pegylated interferon ... Nature.com

New Data from Largest US Hepatitis C Trial Provide Insights Into …  -  Oct 31, 2006
BOSTON, MA -- October 31, 2006 -- New data from the WIN-R trial, the largest hepatitis C study ever conducted in US patients, provide important insights ... DG News

… Shows 12 Weeks of Peginterferon Alfa-2b and Ribavirin Combination ...  -  Jun 22, 2005
Study Shows 12 Weeks of Peginterferon Alfa-2b and Ribavirin Combination Therapy as Effective as 24 Weeks in Certain Hepatitis C Patients With Genotype 2 or ... Pay-Per-View - PR Newswire Europe - HighBeam Research

Press Release: European Commission Approval of New Indication for …  -  Dec 4, 2008
European Commission Approval of New Indication for Roche's Pegasys(R) (peginterferon alfa-2a) Offers Hepatitis C Patients a Second Chance for a Cure. from ... Pay-Per-View - PR Newswire Europe - HighBeam Research

New Clinical Study Results Indicate Higher Early Virologic Response...  -  Apr 11, 2007
VANCOUVER and SAN DIEGO, CA, April 11 /PRNewswire-FirstCall/ -- MIGENIX Inc. (TSX: MGI, OTC: MGIFF), a clinical-stage developer of drugs for infectious ... Free with registration - PR Newswire - AccessMyLibrary.com

MIGENIX Receives Approval for MX-3253 Phase II Combination Viral …  -  May 16, 2006
VANCOUVER and SAN DIEGO, May 16 /PRNewswire-FirstCall/ -- MIGENIX Inc. (TSX: MGI; OTC: MGIFF), a clinical-stage developer of drugs for infectious and ... Free with registration - PR Newswire - AccessMyLibrary.com

Hepatitis C Therapy; Peginterferon alfa-2b benefits patients diagnosed...  -  Apr 26, 2005
According to a study from Italy, "acute hepatitis C often progresses to chronic infection (70%). In this clinical study, we evaluated if early treatment ... Pay-Per-View - Virus Weekly - Factiva, from Dow Jones

What is the safe duration of therapy for patients infected with HCV …  -  Oct 15, 2008
Until prospective trials are conducted, 48 weeks of combination therapy with pegylated interferon plus ribavirin should be used to treat patients with ... Nature.com

Data on PEG-INTRON(R) and REBETOL(R) Combination Therapy in …  -  May 12, 2005
KENILWORTH, NJ, May 12 /PRNewswire-FirstCall/ -- Important new data on PEG-INTRON(R) (peginterferon alfa-2b) and REBETOL(R) (ribavirin, USP) combination ... RedOrbit

MIGENIX Reports Fourth Quarter and Fiscal Year 2006 Financial Results.  -  Jul 13, 2006
VANCOUVER, BC, and SAN DIEGO, CA, July 13 /PRNewswire-FirstCall/ -- MIGENIX Inc. (TSX: MGI; OTC: MGIFF), a clinical-stage developer of drugs for infectious ... Free with registration - PR Newswire - AccessMyLibrary.com

… Shows 12 Weeks of Peginterferon Alfa-2b and Ribavirin Combination ...  -  Jun 22, 2005
Study Shows 12 Weeks of Peginterferon Alfa-2b and Ribavirin Combination Therapy as Effective as 24 Weeks in Certain Hepatitis C Patients With Genotype 2 or ... Pay-Per-View - PR Newswire - HighBeam Research

Meeting Highlights From The Committee For Medicinal Products For …  -  Apr 23, 2007
The European Medicines Agency's (EMEA) Committee for Medicinal Products for Human Use (CHMP) has adopted a positive opinion recommending the granting of a ... Medical News Today - Medical News Today (press release)

Schering-Plough Presents Positive Results From Phase III Melanoma …  -  Jul 14, 2008
Schering-Plough and the European Organization for the Research and Treatment of Cancer have announced positive results from a randomized Phase III melanoma ... RedOrbit

Press Release: Data on PEG-INTRON(R) and REBETOL(R) Combination …  -  May 12, 2005
Data on PEG-INTRON(R) and REBETOL(R) Combination Therapy in Diverse Patient Populations to Be Presented at 2005 Digestive Disease Week (DDW) Meeting. from ... Pay-Per-View - PR Newswire - HighBeam Research

Schering-Plough Highlights Hepatitis C Presentations at the American ...  -  Oct 24, 2006
KENILWORTH, NJ -- More than 50 data presentations involving Schering-Plough's hepatitis products, including PEG- INTRON® (peginterferon alfa-2b) and ... EndoNurse

Data on Schering-Plough's Oral HCV Protease Inhibitor to be Presented...  -  Nov 7, 2005
KENILWORTH, New Jersey, November 7/PRNewswire/ -- Important new data on Schering-Plough's investigational oral protease inhibitor in development for ... biotech-intelligence.com

Bartlett HIV/AIDS Review: March 15, 2005: HIV and Hepatitis  -  Mar 15, 2005
Carrat F, Bani-Sadr F, Pol S, et al. Pegylated interferon alfa-2b vs. standard interferon alfa-2b, plus ribavirin, for chronic hepatitis C in HIV-infected ... Medscape

MIGENIX Completes Enrollment of Celgosivir (MX-3253) Phase IIb HCV …  -  Jun 15, 2006
VANCOUVER/SAN DIEGO, June 15 /PRNewswire-FirstCall/ -- MIGENIX Inc. (TSX: MGI; OTC: MGIFF), a clinical-stage developer of drugs for infectious and ... Free with registration - PR Newswire - AccessMyLibrary.com

Press Release: Telenor Resists Alfa's Attempt to Gain Control of …  -  Jun 7, 2005
Telenor Resists Alfa's Attempt to Gain Control of VimpelCom. from PR Newswire Europe. Highbeam Research – FREE Trial. Pay-Per-View - PR Newswire Europe - HighBeam Research

Summary and Introduction  -  Sep 12, 2005
Both absolute viral load and log decline in viral load from baseline were found clinically useful in predicting sustained virological response and lack of ... Medscape

Press Release: Boceprevir Phase II Study Showed High Rate of …  -  Nov 1, 2008
Boceprevir Phase II Study Showed High Rate of Sustained Response With 28- and 48-Week Regimens in Genotype 1 Treatment-Naive Hepatitis C Patients. from PR ... Pay-Per-View - PR Newswire - HighBeam Research

GI Journal Scan Dec 2004  -  Jan 18, 2005
Journal Scan is the clinician's guide to the latest clinical research findings in Gastroenterology, Hepatology, The American Journal of Gastroenterology, ... Medscape

Approvals: Herceptin, Reyataz, and Peg-Intron  -  May 21, 2007
May 21, 2007 — The European Commission has approved a new indication for trastuzumab infusion, allowing its use with hormonal therapy in the treatment of ... Medscape

New paradigms in the management of hepatitis C virus co-infections  -  Jul 31, 2006
Liver disease has emerged as a major contributor to morbidity and mortality in patients with HIV infection. Hepatitis C virus (HCV) infection is a key ... Nature.com

Treatment of Chronic Hepatitis C Virus in African Americans With …  -  May 12, 2006
Previous studies have documented that sustained virologic response (SVR) is significantly reduced in African Americans with chronic HCV genotype 1 following ... Nature.com

Press Release: Milliman Releases MG-ALFA(R) Version 6.6. - PR …  -  Jun 16, 2008
Milliman Releases MG-ALFA(R) Version 6.6. from PR Newswire. Highbeam Research – FREE Trial. Pay-Per-View - PR Newswire - HighBeam Research

Summary and Introduction  -  Mar 1, 2006
In therapy with standard interferon and ribavirin, five independent risk factors (RF) were predictive of relapse. The aim was to prospectively validate an a ... Medscape

Long-Term Follow-Up of Previous Hepatitis C Virus Positive …  -  Dec 14, 2005
Peginterferon alfa-2b plus ribavirin compared with interferon alfa-2b plus ... Peginterferon alfa- 2b and ribavirin for treatment-refractory chronic ... Nature.com

An overview of European Association for the Study of Liver 41st...  -  May 22, 2006
Hepatitis C patients who have no sign of virus 24 weeks after completing treatment (sustained virological response) can be told they are cured, ... $4.95 - Pharma Marketletter - ECNext

Press Release: Shorter Course of PEG-INTRON(R) and REBETOL(R) …  -  Oct 5, 2005
Shorter Course of PEG-INTRON(R) and REBETOL(R) Combination Therapy Approved in European Union for Certain Hepatitis C Patients With Genotype 1 and Low Viral ... Pay-Per-View - PR Newswire - HighBeam Research

Peginterferon Plus Ribavirin May Be Helpful in Pediatric HCV Infection  -  May 10, 2005
May 10, 2005 — Combination treatment with peginterferon alfa-2b and ribavirin is well tolerated and offers encouraging results for children and adolescents ... Medscape

Celgosivir Combination Therapy Demonstrates Positive Clinical Benefit...  -  Nov 6, 2006
VANCOUVER, BC and SAN DIEGO, CA, Nov. 6 /PRNewswire-FirstCall/ -- MIGENIX Inc. (TSX: MGI, OTC: MGIFF), a clinical-stage developer of drugs for infectious ... $4.95 - PR Newswire - ECNext

Ribavirin (Systemic).  -  Oct 27, 2005
Ribavirin (rye-ba-VYE-rin) is used to treat severe virus pneumonia in infants and young children. It is given by oral inhalation (breathing in the medicine ... Free with registration - USP DI-Volume II, Advice for the... - AccessMyLibrary.com

Ribavirin (Systemic).  -  Feb 1, 2006
Interferon alfa-2b and peginterferon alfa-2b are used to treat a variety of tumors and viruses including the hepatitis C virus. ... Free with registration - USP DI-Volume II, Advice for the... - AccessMyLibrary.com

Albuferon in Phase 2b Trial for the Treatment of Chronic Hepatitis C  -  Jun 2, 2005
For more information about Albuferon, see http://www.hgsi.com/products/albuferon.html. Health professionals interested in more information about trials ... RxPG NEWS

An overview of European Association for the Study of Liver 41st...  -  May 15, 2006
Hepatitis C patients who have no sign of virus 24 weeks after completing treatment (sustained virological response) can be told they are cured, ... Pay-Per-View - Pharma Marketletter - Factiva, from Dow Jones

MIGENIX Reports First Quarter Fiscal Year 2007 Financial Results.  -  Sep 15, 2006
VANCOUVER and SAN DIEGO, Sept. 15 /PRNewswire-FirstCall/ -- MIGENIX Inc. (TSX: MGI; OTC: MGIFF), a clinical-stage developer of drugs for infectious and ... $4.95 - PR Newswire - ECNext

New Study Shows That Pegasys Regimen Provides Higher Cure Rates …  -  Jan 11, 2008
BASEL, Switzerland, November 1 /PRNewswire/ -- A new, independently-conducted study being presented at AASLD shows that PEGASYS(R) (peginterferon alfa-2a ... ITNews

New Study Shows That Pegasys Regimen Provides Higher Cure Rates …  -  Nov 2, 2008
A new, independently-conducted study being presented at AASLD shows that PEGASYS(R) (peginterferon alfa-2a (40KD)) regimens result in higher cure rates for ... Medical News Today - Medical News Today (press release)

Schering-Plough Addresses Major Milestones and Challenges in …  -  Apr 11, 2007
KENILWORTH, NJ, April 11 /PRNewswire-FirstCall/ -- Schering-Plough Corporation reaffirms its commitment to advancing the science and treatment of chronic ... Free with registration - PR Newswire - AccessMyLibrary.com

MIGENIX Initiates Enrollment in Phase IIb Hepatitis C Clinical Study...  -  Nov 22, 2005
VANCOUVER and SAN DIEGO, Nov. 22 /PRNewswire-FirstCall/ -- MIGENIX Inc. (TSX: MGI; OTC: MGIFF), a clinical-stage developer of drugs for infectious and ... biotech-intelligence.com

Schering-Plough Highlights PEGINTRON(TM) And Boceprevir Data …  -  Apr 18, 2008
Colchicine versus peginterferon alfa 2b long term therapy: results of the 4 year COPILOT trial. Afdhal, NH et al. General Session 1, Thursday, April 24, ... Medical News Today - Medical News Today (press release)

MIGENIX Reports Second Quarter Fiscal Year 2007 Financial Results.  -  Dec 13, 2006
VANCOUVER and SAN DIEGO, Dec. 13 /PRNewswire-FirstCall/ -- MIGENIX Inc. (TSX: MGI; OTC: MGIFF), a clinical-stage developer of drugs for infectious and ... Free with registration - PR Newswire - AccessMyLibrary.com

Schering-Plough Highlights PEGINTRON(TM) And Boceprevir Hepatitis C …  -  May 16, 2008
Schering-Plough Corporation (NYSE: SGP), a leader in advancing the science and treatment of chronic hepatitis C virus (HCV) infection, announced that data ... Medical News Today - Medical News Today (press release)

Press Release: MIGENIX receives approval to initiate MX-3253 Phase...  -  Aug 11, 2005
MIGENIX receives approval to initiate MX-3253 Phase IIb combination study in HCV non-responders. from PR Newswire. Highbeam Research – FREE Trial. Pay-Per-View - PR Newswire - HighBeam Research

Experimental Drug Combo Tested in Tough-to-Treat Patients  -  Apr 27, 2005
...by John C. Martin. An experimental combination of medications may be effective in a certain group of people with hepatitis C (HCV) who historically have ... Hepatitis Neighborhood

Press Release: Roche responds to announcement of 'IDEAL' hepatitis C ...  -  Jan 14, 2008
Roche responds to announcement of 'IDEAL' hepatitis C trial results. from PR Newswire. Highbeam Research – FREE Trial. Pay-Per-View - PR Newswire - HighBeam Research

New data show SP's PegIntron to be an effective monotherapy for …  -  Jan 17, 2005
Results from a large international clinical study, organized and sponsored by the Foundation for Liver Research and published in the January 8 issue of The ... Pay-Per-View - Pharma Marketletter - Factiva, from Dow Jones

Treating children with chronic hepatitis C  -  Mar 5, 2005
More than half of 61 children infected with chronic hepatitis C achieved a sustained viral response after treatment with peginterferon-alfa-2b and ribavirin ... innovations report - Innovations-Report

About 60 Clinical Studies Regarding Schering-Plough's Oncology …  -  May 31, 2008
Schering-Plough Corporation (NYSE: SGP) announced that about 80 posters, poster discussions, and oral presentations from about 60 clinical studies relating ... Medical News Today - Medical News Today (press release)

Hepatitis C Virus/HIV Coinfection  -  Apr 13, 2005
Data from 4 major trials evaluating the treatment of hepatitis C virus (HCV) in HIV-HCV coinfection make it clear that many HIV-infected individuals can be ... Medscape

Combining Peginterferon With Weight-Based Ribavirin Increases …  -  Mar 27, 2008
Peginterferon alfa-2b and Weight-Based or Flat-Dose Ribavirin in Chronic ... Peginterferon alfa-2b plus Ribavirin Compared with Interferon alfa-2b plus ... DG News

Press Release: Celgosivir Combination Therapy Demonstrates Positive …  -  Nov 6, 2006
Celgosivir Combination Therapy Demonstrates Positive Clinical Benefit in Chronic Hepatitis C Non-Responder Patients. from PR Newswire. Pay-Per-View - PR Newswire - HighBeam Research

Chronic Hepatitis C in Latinos: Natural History, Treatment Eligibility...  -  Feb 27, 2005
The natural history of chronic hepatitis C and treatment response are different between blacks and Caucasians, but little comparable data is available about ... Nature.com

Associations between the human MHC and sustained virologic response …  -  Apr 17, 2008
Correspondence: Dr LJ Yee, University of Pittsburgh, A511 Crabtree Hall, 130 DeSoto Street, Pittsburgh, PA 15261, USA. E-mail: YeeL@edc.pitt.edu ... Nature.com

Press Release: New Study Shows That Pegasys Regimen Provides …  -  Nov 1, 2008
New Study Shows That Pegasys Regimen Provides Higher Cure Rates for Hepatitis C Patients.(Clinical report) from PR Newswire Europe. Pay-Per-View - PR Newswire Europe - HighBeam Research

Hepatitis C: reviewing the options.(Letter to the editor)  -  Jul 4, 2006
Tom Wong and Samuel Lee (1) mention some extrahepatic manifestations of infection with hepatitis C virus (HCV), but they do not discuss the urticarias. ... Free with registration - CMAJ: Canadian Medical Association... - AccessMyLibrary.com

Results of PEG-INTRON(R) and REBETOL(R) Study in Retreating …  -  Oct 27, 2006
BOSTON, Oct. 27 /PRNewswire-FirstCall/ -- Schering-Plough today reported data from EPIC3, a large ongoing clinical study, showing that retreatment with ... RedOrbit

WIN-R Study Demonstrates Efficacy of Shorter PEG-Intron and Rebetol …  -  Apr 28, 2006
VIENNA, AUSTRIA -- April 28, 2006 -- For patients infected with hepatitis C virus (HCV) genotype 2 or 3, a shorter, 24-week course of therapy with ... DG News

MIGENIX receives approval to initiate MX-3253 Phase IIb combination …  -  Aug 11, 2005
An agreement was completed in July with Schering-Plough for (a) the supply of PEGETRON(TM) (peginterferon alfa-2b powder for solution plus ribavirin 200 mg ... $4.95 - PR Newswire - ECNext

Investigational Agent Effectively Attacks Hepatitis C Virus From New ...  -  May 28, 2007
By Em Brown. WASHINGTON, DC -- May 28, 2007 -- Celgozivir a novel agent that inhibits the alpha-glucosidase I enzyme, prevents the hepatitis C virus (HCV) ... DG News

Brand Names/Synonyms:
Peginterferon alfa-2b is also known by the following brand names and/or synonymsInterferon alpha-2 precursor;Interferon alpha-A;LeIF A; PEG-Intron

Drug Category:
Peginterferon alfa-2b is categorized under the following by the FDA: Antiviral Agents; Immunomodulatory Agents; Antineoplastic Agents; interferons (08:18.20)

Dosage Forms:
POWDER FOR SOLUTION

Absorption:
Not Available

Interactions:
Not Available



Chemical IUPAC Name:
PEGylated human interferon alpha 2b





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