Persantine

This page contains recent news articles, when available, and an overview of Persantine but does not offer medical advice. You should contact your physician with regard to any health issues or concerns.


Overview:

Persantine
(when available)

Pharmacology and use:
Dipyridamole, a non-nitrate coronary vasodilator that also inhibits platelet aggregation, is combined with other anticoagulant drugs, such as warfarin, to prevent thrombosis in patients with valvular or vascular disorders. Dipyridamole is also used in myocardial perfusion imaging, as an antiplatelet agent, and in combination with aspirin for stroke prophylaxis. For as an adjunct to coumarin anticoagulants in the prevention of postoperative thromboembolic complications of cardiac valve replacement and also used in prevention of angina

Mechanism Of Action:
Dipyridamole likely inhibits both adenosine deaminase and phosphodiesterase, preventing the degradation of cAMP, an inhibitor of platelet function. This elevation in cAMP blocks the release of arachidonic acid from membrane phospholipids and reduces thromboxane A2 activity. Dipyridamole also directly stimulates the release of prostacyclin, which induces adenylate cyclase activity, thereby raising the intraplatelet concentration of cAMP and further inhibiting platelet aggregation.

News Articles on Dipyridamole

Steven Girgenti, Irwin Lerner, and Mel Rubin Voted Into Medical Advertising ...  -  ‎Oct 23, 2009‎
He moved to Geigy Pharmaceuticals as sales promotion manager, working on Butazolidin, Tandearil, Anturane, Persantine, and Preludin. ... Reuters

Drug May Aid Aspirin After Ministroke  -  May 18, 2006
Dipyridamole is found in the drugs Aggrenox (which also contains aspirin) and Persantine. A study in The Lancet shows that among people who had already had ... WebMD

What causes my purple blotches?  -  Apr 23, 2005
Moreover, you may be taking too much Persantine, a drug that is supposed to aid circulation by interfering with coagulation. Check with your physician, ... $2.95 - Erie Times-News - NewsBank

Aspirin-Persantine Duo Best After Ischemic Stroke  -  May 19, 2006
By Judith Groch, MedPage Today Senior Writer. UTRECHT, The Netherlands, May 19 — Aspirin teamed with the antiplatelet drug Persantine (dipyridamole) ... MedPage Today

Persantine thallium stress test.  -  May 1, 2006
...* Do not eat or drink anything except water for six hours before the test. Do not eat or drink anything with caffeine for 24 hours (one day) before the test ... Free with registration - CareNotes - AccessMyLibrary.com

Newer Blood Pressure Drug No Better Than Placebo in Preventing Stroke  -  Aug 27, 2008
During two-and-a-half years of follow-up, 9 percent of the patients taking Persantine and aspirin suffered a stroke compared with 8.8 percent of those ... Washington Post

Illinois Appellate Court Reports - CURI v. MURPHY, 366 Ill. App.3d...  -  Jun 27, 2006
On October 30, 2000, Bray underwent a Persantine Cardiolite Stress Test ... Dr. Murphy assumed Bray passed his Persantine test because he could not imagine ... Pay-Per-View - Illinois Appellate Court Reports - Loislaw

Does aggrenox have a generic brand  -  Aug 23, 2008
It is possible to take aspirin and generic persantine as a substitute, but the persantine is not long acting and should be taken at least three times a day. ... HealthCentral.com

Harris v. Commissioner of Social Security, No. CIV S-06-2734-CMK ( …  -  Feb 26, 2008
Notes indicated that Mr. Harris's myocardial study indicated he had a dilated left ventricle on both the Persantine and resting images, and thinning of the ... $2.95 - U.S. District Court, Eastern District... - VersusLaw

Federal Register 2007 - 72 FR 28982 Determination That Protamine …  -  May 23, 2007
NDA 19-243 for PROVENTIL Inhalation Solution, NDA 19-471 for CARDIZEM SR Capsules, and NDA 19-817 for PERSANTINE Injection in the Federal Register of ... Pay-Per-View - Federal Register 2007 - Loislaw

Loislaw Federal District Court Opinions - HARRIS v. COMMISSIONER OF …  -  Feb 26, 2008
Notes indicated that Mr. Harris's myocardial study indicated he had a dilated left ventricle on both the Persantine and resting images, and thinning of the ... Pay-Per-View - Loislaw Federal District Court Opinions - Loislaw

Muy urgente: Gravísima situación médica y secuestro leGAL de Josefina...  -  Apr 1, 2006
Vistos los resultados, el mismo cardiólogo pide que se me realice una centigrafía miocárdica con “thalium persantine� y , entre tanto, me prescribe una ... kaosenlared.net

Should patients with type 2 diabetes asymptomatic for coronary artery...  -  Jun 2, 2005
...during treadmill exercise testing or pharmacologic stress, with use of persantine or adenosine, followed by a repeat resting study several hours later. ... Nature.com

Arteriosclerosis of the Extremities  -  May 15, 2008
Dipyridamole (Persantine) may help prevent complications of PAD when taken along with aspirin. Studies are mixed on the benefits of the combination. ... New York Times

Stroke drugs show similar results, or no benefits  -  Aug 28, 2008
Clopidogrel is sold by Bristol-Myers Squibb under the brand name Plavix while Boehringer Ingelheim GmbH makes dipyridamole under the brand name Persantine. ... Reuters India

McCoy v. Montgomery, 370 Ark. 333 (Ark. 06/21/2007)  -  Jun 21, 2007
On June 25, 1998, Dr. Timothy A. Waack, a cardiologist, performed a Persantine nuclear stress test on Montgomery to evaluate the severity of his known ... $2.95 - Arkansas Supreme Court - VersusLaw

Spontaneous bruising a red flag for doctors .  -  May 10, 2005
My medications are and Persantine. Dear Reader: Spontaneous bruising (without antecedent injury) is always a red flag for doctors, because it may reflect a ... Reading Eagle - Google News Archive

Aminophylline IV : User Ratings covering uses, effectiveness,...  -  May 16, 2008
I was given this drug following Persantine I was to have received 200 mgs, but after 100mg was injected, I went into bigeminy along with an extreme flushing ... WebMD

DON'T STRESS OVER HEART TEST  -  Oct 15, 2006
I was then given a radioactive stress test, preceded by a Persantine infusion. The stress test report says: "Normal pattern of Cardiolite distribution. ... Pay-Per-View - South Florida Sun - Sentinel - ProQuest Archiver

Combined Antithrombotic Therapy Increases Risk of Gastrointestinal …  -  Apr 1, 2007
...dipyridamole (Persantine), and vitamin K antagonists. Pharmacy records also were examined for use of nonsteroidal anti-inflammatory drugs (NSAIDs), ... AAFP News Now

Surgical images: soft tissue recurrent aneurysms.(Continuing Medical ...  -  Oct 1, 2005
The patient still had Canadian Cardiovascular Society class II angina and reversible inferior ischemia on thallium-Persantine scanning. ... Free with registration - Canadian Journal of Surgery - AccessMyLibrary.com

Testing the Heart  -  Mar 23, 2007
An alternative to the Treadmill Test is the use or coronary artery dilators (arterial channel openers), Dipyridamole (commonly known as Persantine) given ... News Today Online

Maine v. Astrue, No. 4:07CV1074 CDP (EDMo. 05/27/2008)  -  May 27, 2008
Dr. Martin administered an electrocardiogram, which showed no acute changes, and he scheduled Maine for a stress Myoview study and Persantine stress test. ... $2.95 - U.S. District Court, Eastern District... - VersusLaw

The cure may be worse than the disease.  -  Nov 8, 2005
The test required injection of radioactive isotope and intravenous administration of a drug Persantine or Dipyridamoleto dilate blood vessels. ... Free with registration - Asia Africa Intelligence Wire - AccessMyLibrary.com

Clinical quiz.  -  Aug 1, 2007
D. Patients who experience headaches with dipyridamole (Persantine). Q12. The childhood management of Turner's syndrome focuses on which of the following? ... Free with registration - American Family Physician - AccessMyLibrary.com

How to take Heparin Injection from Consumer Reports Health.  -  Jan 8, 2007
Motrin) and naproxen (Aleve, Naprosyn); dextran; digoxin (Digitek, Lanoxin); dipyridamole (Persantine, in Aggrenox); hydroxychloroquine (Plaquenil); ... consumerreports.org

Thomas v. Astrue, No. 07-308-GWU (EDKy. 06/04/2008)  -  Jun 4, 2008
A nuclear stress test with Persantine sestambi study was normal with no sign of myocardial ischemia. (Id.). The claimant was discharged stable and ... $2.95 - U.S. District Court, Eastern District... - VersusLaw

Combination therapy better after cerebral ischemia.(Tips)  -  Oct 15, 2006
...but one large study reported a 22 percent relative risk reduction from a combination of 50 mg aspirin and 200 mg dipyridamole (Persantine). ... Free with registration - American Family Physician - AccessMyLibrary.com

Loislaw Federal District Court Opinions - GIBSON v. BARNHART (NDIll. ...  -  Mar 29, 2005
On December 4, 1992, Plaintiff underwent a Persantine stress test. (Tr. 230). A moderate to large posterior wall defect with partial marginal reperfusion ... Pay-Per-View - Loislaw Federal District Court Opinions - Loislaw

Antiplatelet Drugs  -  May 19, 2006
Other members of this family of drugs include abciximab (brand name Reopro), clopidogrel (Plavix), dipyridamole (Persantine), eptifibatide (Integrilin), ... Diabetes Self Management

Salicylates (Systemic).  -  Jul 28, 2005
Cefobid) or Cefotetan (e.g., Cefotan) or Dipyridamole (e.g., Persantine) or Divalproex (e.g., Depakote) or Heparin or Inflammation or pain medicine, ... Free with registration - USP DI-Volume II, Advice for the... - AccessMyLibrary.com

Noninvasive cardiac imaging.  -  Apr 15, 2007
...(2) Pharmacologic stress SPECT myocardial perfusion imaging with vasodilator agents (eg, adenosine [Adenoscan] and dipyridamole [Persantine]) is often used ... $4.95 - American Family Physician - ECNext

Abciximab (Systemic).  -  Aug 1, 2006
...urokinase [eg, Abbokinase]), or Dextran, or Dipyridamole (eg, Persantine, Aggrenox) or Heparin, or Inflammation or pain medicine, except narcotics, ... Free with registration - USP DI-Volume II, Advice for the... - AccessMyLibrary.com

Salicylates (Systemic).  -  Oct 27, 2005
Cefobid) or Cefotetan (e.g., Cefotan) or Dipyridamole (e.g., Persantine) or Divalproex (e.g., Depakote) or Heparin or Inflammation or pain medicine, ... Free with registration - USP DI-Volume II, Advice for the... - AccessMyLibrary.com

Pennsylvania Superior Court Reports - WINSCHEL v. JAIN, 2007 PA …  -  Jul 6, 2007
Dr. Jain then performed another diagnostic test, known as a persantine SPECT scan test,[fn1] on Decedent. No abnormalities were detected by these diagnostic ... Pay-Per-View - Pennsylvania Superior Court Reports - Loislaw

Actavis Group.(RX/GENERIC DRUGS--Profiles)  -  Sep 25, 2006
...amantadine, the generic version of Endo Pharmaceuticals' Symmetrel; and dipyridamole, the generic equivalent of Boehringer Ingelheim's Persantine. ... Free with registration - Chain Drug Review - AccessMyLibrary.com

Lannett Company Receives Approval For Dipyridamole Tablets USP, 25 …  -  Apr 28, 2008
...(ANDA) for Dipyridamole Tablets USP, 25mg, 50mg, and 75mg, the generic equivalent of Persantine® Tablets manufactured by Boehringer Ingelheim GmbH. ... Medical News Today - Medical News Today (press release)

Use of dipyridamole in patients with recent stroke or TIA.(transient ...  -  Aug 1, 2005
...and extended-release dipyridamole (Persantine), compared with placebo or aspirin alone, as noted in the European Stroke Prevention Study 2 (ESPS-2). ... $4.95 - American Family Physician - ECNext

'It really hurts when I walk!' Arterial disease--differential...  -  Jun 1, 2007
Low-dose aspirin does not affect arterial disease but other anti-platelet drugs such as dipyridamole (Persantine[TM]), cilostazol (Pletal[TM]) and ... $4.95 - Dermatology Nursing - ECNext

What is the best management for patients who have a TIA while on...  -  Jul 1, 2006
Persantine Aspirin Trial in cerebral ischemia, II: end point results. Stroke 1985; 16:406-415. (3.) The ESPS Group. The European Stroke Prevention Study ... Free with registration - Journal of Family Practice - AccessMyLibrary.com

FDA Approves Lannett's Dipyridamole Tablets  -  Apr 25, 2008
...drug application for dipyridamole tablets USP, 25mg, 50mg, and 75mg, the generic equivalent of Persantine tablets manufactured by Boehringer Ingelheim. ... RedOrbit

Article: Job growth points interest rates up.(Brief Article) - Pro...  -  Mar 5, 2005
China Chemical Reporter; April 6, 2000 ; 589 words ... ... produce persantine and praziquantel. These products will mainly be exported to the overseas ... Pay-Per-View - Pro Farmer - HighBeam Research

Two-drug combo may improve overactive bladder in some men.(drug …  -  Feb 1, 2007
Taking aspirin together with the antiplatelet drug dipyridamole (Persantine) is more effective at preventing another stroke than taking either drug alone, ... Pay-Per-View - Focus on Healthy Aging - HighBeam Research

Penicillins and Beta-Lactamase Inhibitors (Systemic ).  -  Aug 1, 2006
Anticoagulants (blood thinners) or Dipyridamole (eg, Persantine) or Divalproex (eg, Depakote) or Heparin (eg, Panheprin) or Inflammation or pain medicine ... Free with registration - USP DI-Volume II, Advice for the... - AccessMyLibrary.com

What is the difference between Warfarin and Plavix  -  Sep 1, 2008
Other medications in this class of drug are aspirin, persantine and aggrenox. Unlike warfarin, monitoring blood levels or activity is not necessary. ... HealthCentral.com

Drug Development; Agents that target signaling pathways hold promise...  -  Oct 30, 2005
Aspirin, dipyridamole (Persantine), and thienopyridines (ticlopidine and clopidogrel) are all examples of agents that specifically target discrete platelet ... Pay-Per-View - Heart Disease Weekly - Factiva, from Dow Jones

Antiplatelet therapy in children with left-sided mechanical prostheses  -  Jun 1, 2008
All patients were anticoagulated (warfarin) for 3 months post implantation and then switched to a regimen of aspirin and persantine. ... European Journal of Cardio-Thoracic...

Penicillins (Systemic).  -  Feb 1, 2006
Persantine) or Divalproex (e.g., Depakote) or Heparin (e.g., Panheprin) or Inflammation or pain medicine (except narcotics) or Pentoxifylline (e.g., ... Free with registration - USP DI-Volume II, Advice for the... - AccessMyLibrary.com

De memoires van wielerverzorger Jef D'Hont (1): de zaak-Telekom  -  May 1, 2007
Plus: Persantine, een middel dat de doorbloeding verbetert. En verder, door een stom toeval eraan toegevoegd: Alupent, een product dat de longinhoud ... Humo The Wild Site

University of Pennsylvania; Agents that target signaling pathways...  -  Oct 26, 2005
Aspirin, dipyridamole (Persantine), and thienopyridines (ticlopidine and clopidogrel) are all examples of agents that specifically target discrete platelet ... Pay-Per-View - Biotech Week - Factiva, from Dow Jones

Cephalosporins (Systemic).  -  Aug 1, 2006
Geopen) or Dipyridamole (e.g., Persantine) or Divalproex (e.g., Depakote) or Heparin (e.g., Hepalean, Liquaemin) or Pentoxifylline (e.g., ... Free with registration - USP DI-Volume II, Advice for the... - AccessMyLibrary.com

Drug Development; Agents that target signaling pathways hold promise...  -  Oct 24, 2005
Aspirin, dipyridamole (Persantine), and thienopyridines (ticlopidine and clopidogrel) are all examples of agents that specifically target discrete platelet ... Pay-Per-View - Health & Medicine Week - Factiva, from Dow Jones

Ask the doctor.(creativity and mental illness)  -  Nov 1, 2006
Other drugs that should not be combined with gingko include: warfarin (Coumadin), ticlopidine (Ticlid), clopidogrel (Plavix), dipyridamole (Persantine), ... Free with registration - Mind, Mood & Memory - AccessMyLibrary.com

Narcotic Analgesics and Aspirin (Systemic).  -  Feb 1, 2006
Cefobid) or Cefotetan (e.g., Cefotan) or Dipyridamole (e.g., Persantine) or Divalproex (e.g., Depakote) or Heparin or Medicine for inflammation or pain, ... Free with registration - USP DI-Volume II, Advice for the... - AccessMyLibrary.com

Actavis launches five new products in USA.  -  Jul 17, 2006
...dipyridamole, the active ingredient of Boehringer Ingelheim's anti-platelet drug Persantine; and spironolactone, the generic of Pfizer's Aldactone, ... Free with registration - Pharma Marketletter - AccessMyLibrary.com

Lipicard Technologies Survey: US Cardiologists Ready to Prescribe …  -  Aug 16, 2006
It is well known that all currently available antiplatelet drugs viz- Aspirin, PLAVIX(R), Persantine, Aggrastat, and Ticlid are toxic. ... Free with registration - Business Wire - AccessMyLibrary.com

Clinical question: Does cardiac rehabilitation improve quality of...  -  Dec 1, 2006
His cardiologist prescribed dipyridamole (Persantine, * 75 mg 3 times a day) for dilation of the coronary arteries and for anticoagulation and recommended ... Free with registration - Physical Therapy - AccessMyLibrary.com

Drug Development; Agents that target signaling pathways hold promise...  -  Oct 29, 2005
Aspirin, dipyridamole (Persantine), and thienopyridines (ticlopidine and clopidogrel) are all examples of agents that specifically target discrete platelet ... Pay-Per-View - Obesity, Fitness & Wellness Week - Factiva, from Dow Jones

Drug Development; Agents that target signaling pathways hold promise...  -  Oct 25, 2005
Aspirin, dipyridamole (Persantine), and thienopyridines (ticlopidine and clopidogrel) are all examples of agents that specifically target discrete platelet ... Pay-Per-View - Science Letter - Factiva, from Dow Jones

Washington Administrative Code - WAC 260-70-680 This section …  -  Mar 17, 2006
Dimefline Diphenhydramine Benadryl Dipyridamole Persantine Divalproex Depakote Dobutamine Dobutrex Doxazosin Doxylamine Decapryn Dyphylline Edrophonium ... Pay-Per-View - Washington Administrative Code - Loislaw

Lipicard Technologies Survey: US Cardiologists Ready to Prescribe …  -  Aug 16, 2006
It is well known that all currently available antiplatelet drugs viz- Aspirin, PLAVIX(R), Persantine, Aggrastat, and Ticlid are toxic. ... $4.95 - Business Wire - ECNext

Lipicard Technologies Study: Platrol(R) - A Novel Antiplatelet Drug …  -  Jul 31, 2006
HYDERABAD, India -- All currently available antiplatelet drugs viz- Aspirin, PLAVIX(R), Persantine, Aggrastat, and Ticlid are toxic. $4.95 - Business Wire - ECNext

Aspirin-drug combo better after minor stroke.(aspirin with dipyridamol...  -  Aug 1, 2006
...find Focus on Healthy Aging articles. Taking aspirin together with the antiplatelet drug dipyridamole (Persantine) is more effective at preventing ... Pay-Per-View - Focus on Healthy Aging - HighBeam Research

Loislaw Federal District Court Opinions - MAYEAUX v. US (WDLa. 2006)  -  Jul 20, 2006
Mr. Mayeaux underwent a persantine/cardiolite stress test on May 16, 2001, which revealed a Page 4 "significant reversible defect in distribution of left ... Pay-Per-View - Loislaw Federal District Court Opinions - Loislaw

khoa hoc@doi song/Phai chang thien nhien la vo hai ?  -  Dec 8, 2005
Có thể làm xuất huyết nếu xài chung với thuốc kháng đông hoặc thuốc làm máu loãng như Aspirine, vitamin E , Plavix, Persantine và Ticlid . ... Khoa H�c

Vietnam Review | Chuyên Mục | Hiểu Biết Căn Bản Vá»? Dược Thảo  -  Mar 11, 2006
Không dùng ginkgo biloba (bạch quả) với thuốc trị đau nhức aspirin, thuốc ngừa tai biến não ticlid, persantine; thuốc trị trầm cảm với St John Wort... ... Vietnam Review

'글로벌 ì„?ê°„ 종합ì?¼ê°„ì§€' 아시아투ë?°ì?´  -  Oct 23, 2006
...�사는 협심�� 효과가 있는 약(propanolol)과 심장부하를 줄�는 약(nipedipine), �혈� 예방하는 약(persantine)� 처방했다. � 약복용� �명� 연장시키기는 ... 아시아투��

Sims v. Astrue, No. 07-4085-CV-C-REL-SSA (WDMo. 06/13/2008)  -  Jun 13, 2008
..."Will schedule a Persantine Sestamibi*fn10 ." Dr. Downing assessed complaints of leg pain consistent with claudication. "The patient has diminished pedal ... $2.95 - U.S. District Court, Western District... - VersusLaw

Brand Names/Synonyms:
Persantine is also known by the following brand names and/or synonymsAggrenox; Agilease; Anginal; Apo-Dipyridamole Fc; Apo-Dipyridamole Sc; Apricor; Cardioflux; Cardoxil; Cardoxin; Chilcolan; Cleridium; Cleridium 150; Coribon; Coridil; Coronarine; Corosan; Coroxin; Curantyl; Dipiridamol; Dipyridamine; Dipyridamol; Dipyridamole; Dipyridamole, Pharma; Dipyridan; Dipyudamine; Dypyridamol; Gulliostin; Iv Persantine; Justpertin; Kurantil; Natyl; Novo-Dipiradol; Peridamol; Permiltin; Persantin; Persantine; Piroan; Prandiol; Prandiol 75; Protangix; RA 8; RA-8; Stenocardil; Stenocardiol; Stimolcardio; Usaf Ge-12

Drug Category:
Persantine is categorized under the following by the FDA: Vasodilator Agents; Vasodilator Agents; ATC:B01AC07

Dosage Forms:
tablets

Absorption:
70%

Interactions:
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Chemical IUPAC Name:
2-[[3-[bis(2-hydroxyethyl)amino]-5,10-bis(1-piperidyl)-2,4,7,9-tetrazabicyclo[4.4.0]deca-2,4,7,9,11-pentaen-8-yl]-(2-hydroxyethyl)amino]ethanol





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