Piperazine

This page contains recent news articles, when available, and an overview of Piperazine but does not offer medical advice. You should contact your physician with regard to any health issues or concerns.


Overview:

Piperazine
(when available)

Pharmacology and use:
Piperazine is an antinematodal agent indicated as alternative treatment for ascariasis caused by Ascaris lumbricoides (roundworm) and enterobiasis (oxyuriasis) caused by Enterobius vermicularis (pinworm). Piperazine is especially useful in the treatment of partial intestinal obstruction caused by Ascaris worms, which is a condition primarily seen in children. Used as alternative treatment for ascariasis caused by Ascaris lumbricoides(roundworm) and enterobiasis (oxyuriasis) caused by Enterobius vermicularis (pinworm).

Mechanism Of Action:
Piperazine is a GABA receptor agonist. Piperzine binds directly and selectively to muscle membrane GABA receptors, presumably causing hyperpolarization of nerve endings, resulting in flaccid paralysis of the worm. While the worm is paralyzed, it is dislodged from the intestinal lumen and expelled live from the body by normal intestinal peristalsis.

News Articles on Piperazine

What Are Pinworms (threadworms)? What Causes Pinworm Infection?  -  05 Jan 2010
Piperazine - this medication paralyzes the worm so that it is rapidly expelled out of the bowel. Sometimes the patient is also given senna (a slight ... Medical News Today

Banning 'legal' highs  -  ‎Dec 21, 2009‎
Its sometimes sold as ecstasy or legal E. It is a derivative of piperazine, which is used as an anti-worming agent for farm animals. ... GMTV

The Puzzling Difference Between Schmutz X and Compound 24028 in AstraZeneca  -  ‎Oct 27, 2009‎
By contrast, Schmutz X differs from quetiapine in having an ethyl side chainattached to the upper nitrogen of the piperazine ring. ... IPWatchdog.com

Britain is 'designer drugs' capital of Europe, says EU agency  -  ‎Nov 5, 2009‎
...the active ingredient in his tablets was not the illegal chemical MDMA, but a new legal synthetic drug mCPP, or Piperazine, which has similar effects. ... guardian.co.uk

Charging down a pH gradient  -  ‎Nov 9, 2009‎
Farnan and Moreno designed an IEC system consisting of a cation exchange stationary phase and a mobile phase comprising piperazine, imidazole and tris. ... separationsNOW.com

Medical warning over dance drug  -  Apr 27, 2007
The active ingredient in BZP is piperazine, developed in the 1950s as a ... "Therefore a piperazine poisoning can easily be wrongly diagnosed as an ... BBC News

Warning over 'legal high' pills  -  Mar 20, 2007
BZP stands for Benzyl Piperazine - the main active ingredient is piperazine, which is more commonly used as an anti-worming medicine, in animals and humans. ... BBC News

BASF to Start New Piperazine Chip Plant on Drug Client Demand  -  Nov 21, 2008
By Sheenagh Matthews. Nov. 21 (Bloomberg) -- BASF SE, the world's largest chemical company, plans to start up a new plant to produce piperazine chips in the ... Bloomberg

ImQuest Pharmaceuticals Licenses Piperazine Series of Anti-Cancer …  -  Apr 26, 2006
FREDERICK, Md., April 26 /PRNewswire/ -- ImQuest Pharmaceuticals, Inc. announced today the signing of an exclusive worldwide license for the development and ... RedOrbit

Piperazine (Systemic).  -  Oct 27, 2005
Piperazine (PI-per-a-zeen) belongs to the family of medicines called anthelmintics ant-hel-MIN-tiks. Anthelmintics are used in the treatment of worm ... Free with registration - USP DI-Volume II, Advice for the... - AccessMyLibrary.com

BASF hikes prices for ethyleneamines to offset rising costs  -  Dec 27, 2007
Prices will increase by 100 eur per ton for ethylenediamine and 50 eur per ton each for aminoethylethanolamine, diethylenetriamine, piperazine and AMIX 1000 ... Forbes

Anhydrous piperazine: slow demand growth.(Fine and Specialty) |...  -  May 16, 2008
Anhydrous piperazine: slow demand growth.(Fine and Specialty) ... find China Chemical Reporter articles. Anhydrous piperazine is an important fine chemical ... Pay-Per-View - China Chemical Reporter - HighBeam Research

… of Federal Regulations - 21 CFR § 520.2380f Thiabendazole, piperazi...  -  Jul 11, 2006
21 CFR § 520.2380f Thiabendazole, piperazine phosphate powder. ... 2 grams of thiabendazole and 2.5 grams of piperazine (0.3 ounce of powder) per 100 pounds ... Pay-Per-View - United States Code of Federal Regulation... - Loislaw

Severe supply shortage of piperazine.  -  Apr 16, 2005
Severe supply shortage of piperazine. Piperazine is an important pharmaceutical intermediate, and mainly used in pharmaceutical sector to synthesize ... $9.94 - China Chemical Reporter - Alacra Store

PIPERAZINE (Oral route) - PI-per-a-zeen.(Drug overview)  -  May 1, 2007
Piperazine belongs to the family of medicines called anthelmintics. Anthelmintics are used in the treatment of worm infections. ... Free with registration - USP DI-Volume II, Advice for the... - AccessMyLibrary.com

Anhydrous piperazine: slow demand growth.  -  May 16, 2008
Anhydrous piperazine: slow demand growth. Anhydrous piperazine is an important fine chemical extensively used in pharmaceutical, pesticide, dyestuff and ... $20.00 - China Chemical Reporter - Alacra Store

Severe supply shortage of piperazine.(MARKET REPORT: Fine …  -  Apr 16, 2005
Severe supply shortage of piperazine.(MARKET REPORT: Fine Chemicals) ... find China Chemical Reporter articles. Piperazine is an important pharmaceutical ... Pay-Per-View - China Chemical Reporter - HighBeam Research

Press Release: New piperazine flaker for BASF in Antwerp. - M2 …  -  Nov 21, 2008
New piperazine flaker for BASF in Antwerp. from M2 Presswire. Highbeam Research – FREE Trial. Pay-Per-View - M2 Presswire - HighBeam Research

… Regulations - 21 CFR § 520.1802a Piperazine-carbon disulfide...  -  Jul 11, 2006
21 CFR § 520.1802a Piperazine-carbon disulfide complex suspension. ... Each fluid ounce of suspension contains 7.5 grams of piperazine-carbon disulfide ... Pay-Per-View - United States Code of Federal Regulation... - Loislaw

piperazine -- Britannica Online Encyclopedia  -  Jun 20, 2008
Britannica online encyclopedia article on piperazine: anthelmintic drug used in the treatment of intestinal roundworm infection in humans and domestic ... Subscription - Encyclopedia Britannica

… Regulations - 21 CFR § 520.1805 Piperazine phosphate with thenium ...  -  Jul 11, 2006
21 CFR § 520.1805 Piperazine phosphate with thenium closylate tablets. ... Each scored tablet contains the equivalent of 250 milligrams piperazine ... Pay-Per-View - United States Code of Federal Regulation... - Loislaw

A Practical Synthesis of Differentially Protected 2-(Hydroxymethyl) …  -  Oct 4, 2007
The piperazine ring is a favored structural element in medicinal chemistry and is often ... 2 Piperazine-2-carboxylic acid is traditionally prepared from ... Environmental Science & Technology

Pneumocystis Carinii Therapy; Piperazine-linked bisbenzamidines...  -  Feb 8, 2005
..."Trimethoprim-sulfamethoxazole and pentamidine isethionate have been used extensively for the prophylaxis and therapy of pneumonia caused by Pneumoeystis ... Pay-Per-View - Cancer Weekly - Factiva, from Dow Jones

… States Code of Federal Regulations - 21 CFR § 520.1806 Piperazine ...  -  Jul 11, 2006
21 CFR § 520.1806 Piperazine suspension. (a) Specifications. Each milliliter of suspension contains piperazine monohydrochloride equivalent to 33.5 ... Pay-Per-View - United States Code of Federal Regulation... - Loislaw

University of Cincinnati; Piperazine-linked bisbenzamidines active …  -  Feb 9, 2005
..."Trimethoprim-sulfamethoxazole and pentamidine isethionate have been used extensively for the prophylaxis and therapy of pneumonia caused by Pneumoeystis ... Pay-Per-View - Biotech Week - Factiva, from Dow Jones

Genoral - Piperazine oestrone sulfate - Medical Drug  -  Jan 2, 2008
Genoral contains a drug that acts like oestrogen, and thus can help correct symptoms in oestrogen-deficient women. Genoral is usually taken daily in a dose ... Virtual Medical Centre - The Virtual Medical Centre

… States Code of Federal Regulations - 21 CFR § 520.1803 Piperazine ...  -  Jul 11, 2006
21 CFR § 520.1803 Piperazine citrate capsules. (a) Specifications. Piperazine citrate capsules contain piperazine citrate equivalent to 140 milligrams of ... Pay-Per-View - United States Code of Federal Regulation... - Loislaw

Benzylpiperazine (PEP) Pills Are Dangerous And Illegal, UK  -  Mar 28, 2007
There are piperazine containing medicines for human use which must be sold in ... Any other pills containing piperazine or its salts or derivatives would be ... Medical News Today - Medical News Today (press release)

Pneumocystis Carinii Therapy; Piperazine-linked bisbenzamidines...  -  Feb 12, 2005
..."Trimethoprim-sulfamethoxazole and pentamidine isethionate have been used extensively for the prophylaxis and therapy of pneumonia caused by Pneumoeystis ... Pay-Per-View - Obesity, Fitness & Wellness Week - Factiva, from Dow Jones

… States Code of Federal Regulations - 21 CFR § 520.1804 Piperazine ...  -  Jul 11, 2006
21 CFR § 520.1804 Piperazine phosphate capsules. (a) Specifications. Each capsule contains 120, 300, or 600 milligrams of piperazine phosphate monohydrate. ... Pay-Per-View - United States Code of Federal Regulation... - Loislaw

… of concentrated aqueous potassium carbonate/piperazine for...  -  Feb 15, 2005
Piperazine contributes to a CO(sub)2 absorption rate as much as four times faster than conventional absorbents (eg, MEA, DEA/K(sub)2CO(sub)3 and PZ/MDEA). Pay-Per-View - Ei EnCompass: Environment - Factiva, from Dow Jones

… States Code of Federal Regulations - 21 CFR § 520.1807 Piperazine.  -  Jul 11, 2006
21 CFR § 520.1807 Piperazine. (a) Specifications. A soluble powder or liquid containing piperazine dihydrochloride or dipiperazine sulfate, equivalent to 17 ... Pay-Per-View - United States Code of Federal Regulation... - Loislaw

Police swoop on Dunedin house  -  Jul 9, 2008
...seized more than an ounce of cannabis, 186 "party pill" capsules and more than 350g of benzyl-piperazine (BZP) from a Maitland St house, police said. ... Otago Daily Times

Federal Register 2005 - 70 FR 17319 New Animal Drugs; Change of …  -  Apr 6, 2005
Section 520.1806 is revised to read as follows: § 520.1806 Piperazine suspension. ... Each milliliter of suspension contains piperazine monohydrochloride ... Pay-Per-View - Federal Register 2005 - Loislaw

piperazine | Definition of piperazine | HighBeam.com: Online Dictionar...  -  Jul 12, 2006
Find out what piperazine means: The Oxford American College Dictionary has the definition of piperazine. Research related newspaper, magazine, ... Pay-Per-View - Oxford American College Dictionary - HighBeam Research

Latest drug craze in Britain's clubs alarms doctors  -  Apr 28, 2007
The active ingredient in BZP is piperazine, which was developed in the 1950s as a ... Therefore a piperazine poisoning can easily be wrongly diagnosed as an ... New Zealand Herald

Illinois Administrative Code - 77 Ill. Adm. Code 790.7260 PIPERAZINE ...  -  Aug 10, 2005
77 Ill. Adm. Code 790.7260 PIPERAZINE CITRATE (Repealed) Repealed. (Source: Repealed at 17 Ill. Reg. 15916, effective September 20, 1993) ... Pay-Per-View - Illinois Administrative Code - Loislaw

… States Code of Federal Regulations - 21 CFR § 556.513 Piperazine.  -  Jul 11, 2006
21 C.F.R. § 556.513 Piperazine. A tolerance of 0.1 part per million piperazine base is established for edible tissues of poultry and swine. ... Pay-Per-View - United States Code of Federal Regulation... - Loislaw

… Code - 77 Ill. Adm. Code 790.3875 ESTROPIPATE (PIPERAZINE …  -  Aug 10, 2005
77 Ill. Adm. Code 790.3875 ESTROPIPATE (PIPERAZINE ESTRONE SULFATE) (Repealed) Repealed. (Source: Repealed at 17 Ill. Reg. 15916, effective September 20, ... Pay-Per-View - Illinois Administrative Code - Loislaw

… Regulations - 21 CFR § 520.1802b Piperazine-carbon disulfide...  -  Jul 11, 2006
21 CFR § 520.1802b Piperazine-carbon disulfide complex boluses. (a) Specifications. Each bolus contains 20 grams of piperazine-carbon disulfide complex. ... Pay-Per-View - United States Code of Federal Regulation... - Loislaw

Absorption of carbon dioxide with piperazine and its mixtures in a...  -  Apr 15, 2006
The removal efficiency of CO(sub)2 from gases containing 10% CO(sub)2 by the aqueous solutions containing piperazine (PZ) and its mixture with ... Pay-Per-View - Ei EnCompass: Environment - Factiva, from Dow Jones

… Regulations - 21 CFR § 520.1802c Piperazine-carbon disulfide...  -  Jul 11, 2006
21 C.F.R. § 520.1802c Piperazine-carbon disulfide complex with ... Each fluid ounce contains 5 grams of piperazine-carbon disulfide complex and 0.83 gram of ... Pay-Per-View - United States Code of Federal Regulation... - Loislaw

… Regulations - 21 CFR § 520.1802 Piperazine-carbon disulfide...  -  Jul 11, 2006
21 C.F.R. § 520.1802 Piperazine-carbon disulfide complex oral dosage forms. Copyright © 2009 Loislaw.com, Inc. All Rights Reserved. Pay-Per-View - United States Code of Federal Regulation... - Loislaw

'Party pills' on sale over the counter  -  May 15, 2007
Meintjies added: "Piperazine has been taken off the market in some European ... BZP products could be mislabelled as containing "piperazine blend", ... Independent Online

Federal Register 2008 - 73 FR 51823 International Drug Scheduling; …  -  Sep 5, 2008
1-(4-Methoxyphenyl)piperazine (MeOPP) 8. 1-(3,4-methylenedioxybenzyl)piperazine (MDBP) 9. Gamma-butyrolactone 10. 1,4-Butanediol One of the essential ... Pay-Per-View - Federal Register 2008 - Loislaw

Pennsylvania Code of Regulations - 28 Pa. Code § 25.58B. Generically ...  -  Jul 16, 2005
Ser Paco Pharmaceutical Ser Ocu-Carpine Ocumed Ocumed PIPERAZINE CITRATE Syrup Piperazine Citrate Barre Drug National Pharmaceutical Piperazine Citrate ... Pay-Per-View - Pennsylvania Code of Regulations - Loislaw

삼진제약, í•­ë°”ì?´ëŸ¬ìŠ¤Â·í•­ì•” 신물질 개발 ë°•ì°¨  -  Apr 5, 2007
...치료제 개발ì?„ 위한 연구과제로 ì„ ì •ë??다"ë©° "피페ë?¼ì§„(Piperazine) 계열ì?˜ í•­ì•” 신물질 ë˜?한 미국 국립 암연구소(NCI)로부터 ê·¸ íƒ?월성ì?„ ì?¸ì •받는 등 항암제, ... 머니투ë?°ì?´

United States Code of Federal Regulations - 21 CFR § 573.940 Silicon ...  -  Jul 11, 2006
...as follows: Feed component Limitations (percent) BHT (butylated hydroxytoluene) 2 Methionine hydroxy analog and its calcium salts 1 Piperazine, ... Pay-Per-View - United States Code of Federal Regulation... - Loislaw

Next generation of party pills to roll out  -  Jan 4, 2008
Parliament passed the Misuse of Drugs Amendment Act in February, banning the active ingredient in party pills — piperazine, commonly known as BZP ... Stuff.co.nz

Independent Nurse: Clinical - Preventing threadworms.  -  Oct 29, 2007
Mebendazole and piperazine cure around 90 per cent of infestations.3 ... Piperazine phosphate is the only drug treatment for threadworms that can be given ... Free with registration - GP - AccessMyLibrary.com

중국, Piperazine 공급부족 심ê°?  -  Aug 9, 2005
Piperazine� �약중간체� 하나로 Piperazine Sulfate, Norfloxacin, Pipendic Acid, Quinolones, Rifampin 합성� 사용�며 섬유, 염료, �쇄, 고무 가황촉진제나 ... �로커스

Shops sell illegal 'party pills'.  -  Jan 10, 2007
She said: "Given the side effects associated with piperazine/BZP, ... But piperazine - an ingredient in all three - is used as a wormer by both vets and ... Free with registration - Europe Intelligence Wire - AccessMyLibrary.com

… - 21 CFR § 520.1242c Levamisole hydrochloride and piperazine dihydr  -  Jul 11, 2006
21 C.F.R. § 520.1242c Levamisole hydrochloride and piperazine dihydrochloride. (a) Specifications. (1) The drug is an aqueous solution which contains in ... Pay-Per-View - United States Code of Federal Regulation... - Loislaw

Federal Register 2008 - 73 FR 60705 International Drug Scheduling; …  -  Oct 14, 2008
1-(3-trifluoromethylphenyl) piperazine; 1-(3-chlorophenyl) piperazine; 1-(4-Methoxyphenyl) piperazine; 1-(3,4-methylenedioxybenzyl) piperazine; ... Pay-Per-View - Federal Register 2008 - Loislaw

Mind-altering drugs: does legal mean safe?  -  Sep 29, 2006
Stargate now produces and sells a range of pills based on piperazine blends. BZP is often combined with another piperazine, ... New Scientist

New to poultry keeping  -  Aug 19, 2006
Maybe give the Piperazine twice .. then the other worming med ... Piperazine should be given in the drinking water twice, with a 3-week interval. ... ThePoultrySite.com

Smoking Reduces Breast Tenderness During Oral Estrogen-Progestogen …  -  Feb 27, 2005
The placebo and piperazine interventions were double-blind and ... For the present analyses, we pooled the two groups receiving piperazine estrone sulfate ... RedOrbit

… - 21 CFR § 520.2520g Trichlorfon, phenothiazine, and piperazine...  -  Jul 11, 2006
21 CFR § 520.2520g Trichlorfon, phenothiazine, and piperazine dihydrochloride powder. (a) Specifications. Each 54.10 grams (1.91 ounces) of water ... Pay-Per-View - United States Code of Federal Regulation... - Loislaw

OTC: Back to school.(analysis of head lice infections)  -  Aug 18, 2007
For piperazine (combined with senna) a single dose, repeated after two weeks, ... Piperazine paralyses the threadworms and they are then excreted; ... Free with registration - Chemist & Druggist - AccessMyLibrary.com

… - 40 CFR § 721.10102 Diphosphoric acid, compd. with piperazine...  -  Dec 31, 2008
40 CFR § 721.10102 Diphosphoric acid, compd. with piperazine (1:1). (a) Chemical substance and significant new uses subject to reporting. ... Pay-Per-View - United States Code of Federal Regulation... - Loislaw

… Regulations - 21 CFR § 520.763c Dithiazanine iodide and piperazine...  -  Jul 11, 2006
21 CFR § 520.763c Dithiazanine iodide and piperazine citrate suspension. (a) Specifications. Each milliliter of the drug contains 69 milligrams of ... Pay-Per-View - United States Code of Federal Regulation... - Loislaw

Osaka University, Japan; Osaka University, Japan, scientists describe...  -  Dec 5, 2006
..."New series of radioiodinated analogues of 1-[2-(3,4-dimethoxyphenyl)ethyl]-4-[3-(2-iodophenyl)propyl]piperazine (o-BON) and 1-[2-(3 ... Pay-Per-View - Life Science Weekly - Factiva, from Dow Jones

Pharmacyupdate: Conquering creepy crawlies  -  Apr 8, 2006
Piperazine has been in use as an enterobiacide for many years, ... Mebendazole kills the parasite, whereas piperazine causes flaccid paralysis by blocking ... Pay-Per-View - Chemist & Druggist - Factiva, from Dow Jones

Clubbers snap up new legal high  -  Dec 13, 2005
Licensed companies are now allowed to make and sell piperazine-based highs. The bulk of Britain's supply is imported from New Zealand where they are ... guardian.co.uk

Xinhua - English  -  Jun 14, 2006
The main active ingredients are benzyl piperazine (BZP) and triflouro phenyl methyl piperazine (TFMPP). These substances are produced synthetically. ... 新�网

Warning over club drug after woman collapses | Article from Evening …  -  Apr 27, 2007
The active ingredient in BZP is piperazine, which was developed in the Fifties as a veterinary antiworm medicine. It has become an increasingly popular ... Pay-Per-View - Evening Standard - London - HighBeam Research

Innovative Liposomes as a Transfollicular Drug Delivery System: …  -  Jun 23, 2005
Carboxyfluoresceine (Molecular Probes) was dissolved at 100 mM in 10 mM N-[2-hydroxyethyl]piperazine-N'-[2-ethanesulphonic acid] and 150 mM NaCl, ... Nature.com

… Regulations - 40 CFR § 721.9800 Poly(substituted triazinyl) piperaz...  -  Jul 11, 2006
...(1) The chemical substance poly(substituted triazinyl) piperazine (PMN P-88-436) is subject to reporting under this section for the significant new uses ... Pay-Per-View - United States Code of Federal Regulation... - Loislaw

Independent Nurse: Clinical - Parasites - Treating cases of threadworm...  -  Sep 9, 2005
Efficacy studies suggest that the vermicides piperazine and mebendazole ... Piperazine is available as a tablet or sachets of powder that can be mixed in ... Pay-Per-View - GP - Factiva, from Dow Jones

Loislaw Federal District Court Opinions - BAYER AG v. DR. REDDY'S …  -  Oct 25, 2007
Even if the inventors' success with a piperazine DBO provided a motivation to use DBOs at the 7-position (beyond a motivation to try), ... Pay-Per-View - Loislaw Federal District Court Opinions - Loislaw

Teen's fake pills shame  -  Oct 23, 2008
They were a substance called Piperazine, said the barrister. ... Mr Rouch said Piperazine was regarded as an Ecstasy substitute and sometimes called Legal E ... South Wales Evening Post

anthelmintic -- Britannica Online Encyclopedia  -  Jun 5, 2008
Piperazine, introduced into human medicine about 1950 and shortly thereafter ... Piperazine, still extensively used for infections of domesticated animals, ... Subscription - Encyclopedia Britannica

Party pills users gamble with brain and body harm  -  Jan 22, 2007
Andrew Brown, a poison information officer with the centre, said pills containing piperazine and BZP may induce severe toxicity in pregnant women which in ... Bay Of Plenty Times - The Bay of Plenty Times

Summer cleaning? What about intestinal parasites?(SPECIAL SECTION: …  -  Jul 1, 2006
...(31) Piperazine is an anthelmintic drug that has been used to treat pinworm and roundworm infections in humans for decades. ... Free with registration - Townsend Letter for Doctors and Patients - AccessMyLibrary.com

Party pills: BZP safety review  -  Jan 26, 2006
Several different piperazine derivatives are known to act as serotonin agonists at a variety of target receptors, principally the 5HT1A, 5HT1B, ... scoop.co.nz

Responsiveness of 5-H[T.sub.1A] and 5-H[T.sub.2] receptors in the rat...  -  Jul 1, 2005
...[5-HT.sub.2C] receptor agonist 3-chlorophenyl piperazine dihydrochloride (mCPP). ... ou du dychlorhydrate de piperazine 3-chlorophenyl (mCPP), ... Free with registration - Journal of Psychiatry and Neuroscience - AccessMyLibrary.com

Dexfenfluramine and norfenfluramine: comparison of mechanism of …  -  Oct 1, 2005
...(fluoxetine) and 5-HT 1B/2C receptor agonists [1-(3-trifluoromethyl-phenyl)-piperazine and 1-(3-chlorophenyl) piperazine]. The anorexia caused by these ... AJP-Regul Integr Comp Physiology...

Structure−Activity Relationship of Quinoline Derivatives as Potent...  -  Sep 28, 2006
The 3-position on the piperazine ring was also found to play an appreciable role, ... Replacing the piperazine ring proved difficult, with 1,4-diazepanes ... Environmental Science & Technology

WHO expert committee on specifications for pharmaceutical preparations...  -  Aug 1, 2005
9930385 phenoxymethylpenicillin potassium 200mg 176075 9930387 phenytoin 100mg 179089 9930388 piperazine adipate 100mg 197212 9930389 piperazine citrate ... Free with registration - Technical Report Series - AccessMyLibrary.com

Dopamine transporter ligand binding domains analyzed through …  -  Apr 1, 2005
A wide range of structurally distinct compounds such as the psychostimulant cocaine and GBR 12909, a piperazine derivative, bind to DAT and block its ... $4.95 - Proceedings of the North Dakota Academy... - ECNext

BASF increases prices for ethyleneamines.  -  Nov 16, 2006
BASF is raising its prices for ethyleneamines (ethylenediamine, diethylenetriamine, aminoethylethanoleamine, piperazine chips and piperazine solution) ... $4.95 - M2 Presswire - ECNext

Press Release: BASF increases prices for ethyleneamines. - M2 …  -  Nov 16, 2006
BASF is raising its prices for ethyleneamines (ethylenediamine, diethylenetriamine, aminoethylethanoleamine, piperazine chips and piperazine solution) ... Pay-Per-View - M2 Presswire - HighBeam Research

NE Chemcat Corp tenders to purchase shares of itself - Deal Snapshot ...  -  Jan 13, 2005
Piperazine salts and derivatives, Amines NES, Amides NES, Carbamates, Esters and salts of…blowing agent, solvent and aerosol needs. ... Pay-Per-View - deals - Alacra Store

Researching the toxicity of party pills: party pill use is on the...  -  Dec 1, 2005
Three months ago a 16-year-old female had a life threatening event as a result of 1-Benzyl piperazine (BZP), the main ingredient in most party pills in New ... Pay-Per-View - Kai Tiaki: Nursing New Zealand - HighBeam Research

United States Code of Federal Regulations - 21 CFR § 177.2550 Reverse...  -  Jul 11, 2006
4422-95-1) with piperazine (CAS Reg. No. 110-85-0) and 1,2-diaminoethane (CAS Reg. No. 107-15-3). The membrane is the food-contact layer and may be applied ... Pay-Per-View - United States Code of Federal Regulation... - Loislaw

Factiva Search  -  Feb 7, 2005
Pneumocystis Carinii Therapy; Piperazine-linked bisbenzamidines active against Pneumocystis ... 2005 FEB 7 - (NewsRx.com & NewsRx.net) -- Piperazine-linked ... Pay-Per-View - Hematology Week - Factiva, from Dow Jones

Factiva Search  -  Feb 7, 2005
Pneumocystis Carinii Therapy; Piperazine-linked bisbenzamidines active against Pneumocystis ... 2005 FEB 7 - (NewsRx.com & NewsRx.net) -- Piperazine-linked ... Pay-Per-View - AIDS Weekly - Factiva, from Dow Jones

Wisconsin Administrative Code - APPENDIX A TO CHAPTER NR 235 — …  -  Jul 16, 2005
...neutralize with nickel base Piperazine Reductive amination of ethanol amine (ammonia and ... N-Dimethylpiperazine Condensation piperazine + formaldehyde ... Pay-Per-View - Wisconsin Administrative Code - Loislaw

Article: HEAD HUNT; Call for ban on shops that sell pep pills over...  -  Sep 24, 2006
...'Pep' pills contain the active ingredient piperazine / benzylpiperazine ... ... Any other pills containing piperazine or its salts, e.g. BZP or PEP pills ... Pay-Per-View - Sunday Mirror - HighBeam Research

United States Code of Federal Regulations - Appendix A to Part 414 — ...  -  Jul 11, 2006
...neutralize with Nickel base Piperazine/Reductive amination of ethanol amine ... catalyst) N,N-Dimethylpiperazine/Condensation piperazine + formaldehyde, ... Pay-Per-View - United States Code of Federal Regulation... - Loislaw

Chemicals, raw materials & specialties.(ABIETIC ACID-4.4'-BIS( …  -  Jan 1, 2007
N-ACETYL PIPERAZINE Organo Fine Chemicals N-ACETYL-4-PIPERIDONE Alfa Aesar, A Johnson Matthey Company N-ACETYL-L-PROLINE COMPLANT NINGBO IMP.& EXP. ... Free with registration - Chemical Week - AccessMyLibrary.com

Chemicals, raw materials & specialties.(ABIETIC ACID-4.4'-BIS( …  -  Jan 1, 2007
N-ACETYL PIPERAZINE Organo Fine Chemicals N-ACETYL-4-PIPERIDONE Alfa Aesar, A Johnson Matthey Company N-ACETYL-L-PROLINE COMPLANT NINGBO IMP.& EXP. ... $4.95 - Chemical Week - ECNext

Ancora pastiglie che distruggono la vita dei giovani  -  Apr 30, 2007
In realtà le piperazine sono usate già da tempo come droghe; si sono diffuse negli anni novanta soprattutto in Nuova Zelanda e Australia, non a caso sono ... yahoo.net

Counterfeit medicines: the pills that kill  -  Apr 5, 2008
They are not counterfeits, but capsules of BZP - piperazine - a worming treatment sold illegally in clubs and at music festivals to produce amphetamine-type ... Telegraph.co.uk

pinworm -- Britannica Online Encyclopedia  -  Jun 20, 2008
Pinworms can be eradicated with piperazine or vyprinium embonate. > piperazine anthelmintic drug used in the treatment of intestinal roundworm infection in ... Subscription - Encyclopedia Britannica

Loislaw Federal District Court Opinions - ELI LILLY & CO. v. ZENITH …  -  Apr 14, 2005
Speculation abounded inside Lilly regarding possible causes, including reactions involving the "piperazine nitrogen" and the fluorine atom. ... Pay-Per-View - Loislaw Federal District Court Opinions - Loislaw

Press Release: BASF increases capacity for epsilon-caprolactone. - M2...  -  Nov 15, 2007
Article: New piperazine flaker for BASF in Antwerp. ... Piperazine is used to produce pharmaceuticals, flame retardants and adhesives. ... Pay-Per-View - M2 Presswire - HighBeam Research

United States v. Dotz, 446 F.3d 632, 2006 Fed.App. 0153P (6th Cir....  -  May 8, 2006
Nathan Dotz pled guilty to possessing trifluoromenthylphenyl piperazine (TMFPP), a Schedule I narcotic, with the intent to distribute, and to possessing ... $2.95 - U.S. Court of Appeals, Sixth Circuit - VersusLaw

`Government will consider banning nimulid'  -  Feb 18, 2006
...nise, novalgin, ciza syspride, droperole, furozone, lomofen, furacin, agarol, D'cold, Vicks Action 500, sioril, piperazine and enteroquinol etc. ... Hindu

MPs told of party-pill threat to toddlers  -  Oct 11, 2007
The figures show that from July 2002 to last October, the centre was contacted regarding 16 children and teenagers under 16 consuming piperazine-based party ... New Zealand Herald

Hypertension and ulcers  -  Jul 9, 2006
Mebex) or piperazine for round worms, niclosemide/albendazole for flukes and praziquental for tapeworms. A a course of de-worming medicines does not protect ... The Hindu

Coffa unaware of trio's positive tests report  -  Dec 8, 2005
It is understood they returned positive samples to the banned stimulant benzyl piperazine at the national championships in Brisbane in October. ... Sydney Morning Herald

Man blames party pills for sex attack  -  Jan 17, 2007
BZPs are benzyl piperazine pills, a popular type of party pill said to induce feelings of euphoria, energy and heightened senses. ... New Zealand Herald

Abl inhibitor BMS354825 binding mode in Abelson kinase revealed by …  -  Apr 28, 2005
In fact, while the piperazine moiety of BMS354825 is aligned to the one of imatinib in the closed conformation (Figure 1a), it points in the opposite ... Nature.com

Restraints on party pills delayed  -  Apr 2, 2005
Party pills, often incorrectly described as herbal highs, are pills based on the synthetic piperazine compounds BZP and TFMPP, which mimic the effects of ... New Zealand Herald

Brand Names/Synonyms:
Piperazine is also known by the following brand names and/or synonymsAnatensol; Antepan; Antepar; Antiren; Asca-Trol No. 3; Bryrel; Dapotum; Diethylenediamine; Diethyleneimine; Dispermine; Entacyl; Eraverm; Fluphenazine Dihydrochloride; Hexahydropyrazine; Lumbrical; Lyogen; Moditen; Multifuge; Omca; Pacinol; Permitil; Piperazidine; Piperazin; Piperazine; Piperazine Anhydrous; Piperazine Citrate; Piperazine, Anhydrous; Pipersol; Prolixin Decanoate; Pyrazine Hexahydride; Pyrazine, Hexahydro-; Siqualone; Tasnon; Tensofin; UN 2579; Upixon; Uvilon; Valamina; Vermex; Vermidol; Worm-Away; Wurmirazin

Drug Category:
Piperazine is categorized under the following by the FDA: Antinematodal Agents; Anthelmintics; ATC:P02CB01; ATC:R03DA09

Dosage Forms:
CAPSULE; DROPS; LIQUID; POWDER; POWDER FOR SOLUTION; SOLUTION; SUSPENSION; SYRUP; TABLET

Absorption:
Rapidly absorbed from the gastrointestinal tract

Interactions:
Not Available



Chemical IUPAC Name:
piperazine





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