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PipobromanThis page contains recent news articles, when available, and an overview of Pipobroman but does not offer medical advice. You should contact your physician with regard to any health issues or concerns.Overview: Pipobroman (when available) Pipobroman is an antineoplastic agent. Specifically it is a piperazine derivative with a chemical structure close to that of many DNA alkylating agents. Pipobroman has well documented clinical activity against polycythemia vera and essential thrombocythemia. For the treatment of polycythaemia vera and refractory chronic myeloid leukaemia. Mechanism Of Action: The mechanism of action is uncertain but pipobroman is thought to alkylate DNA leading to disruption of DNA synthesis and eventual cell death. News Articles on Pipobroman … , Diagnostik und Therapie: Pipobroman im Ausland zugelassen - Jan 25, 2008 Zum leukämogenen Risiko von Pipobroman bei der ET gibt es Langzeitdaten, die kein erhöhtes Risiko für eine Leukämie bei der ET gezeigt haben (3). ... Deutsches Ärzteblatt Leukemia - Comparison of whole blood vs purified blood granulocytes... - Feb 15, 2007 Twelve MPD patients (five PV, five ET and two IMF) had been receiving cytoreductive treatment (pipobroman or hydroxyurea); all other patients were examined ... Nature.com Essential thrombocythemia in young individuals: frequency and risk … - Apr 12, 2007 ...of hematological evolution in three French prospective studies of hydroxyurea and pipobroman in polycythemia vera and essential thrombocythemia. ... Nature.com Alabama Administrative Code - 540-X-4-.07 Emergency Prescription … - Aug 17, 2005 Uracil Mustard (II) Nitrosoureas I Lomustine II Carmustine III Streptozocin (III) Thiotepa (IV) Busulfan (V) Pipobroman (VI) Cisplatin (iii) Antimetabolite ... Pay-Per-View - Alabama Administrative Code - Loislaw Alabama Administrative Code - 680-X-2-.26 Emergency Prescription … - Aug 17, 2005 Streptozocin (III) Thiotepa (IV) Busulfan (V) Pipobroman (VI) Cisplatin (iii) Antimetabolite (I) Methotrexate (II) Fluorouracil and Floxuridine (III) ... Pay-Per-View - Alabama Administrative Code - Loislaw Acute Leukemia in Polycythemia Vera - Jul 1, 2005 Treatment of polycythemia vera: the use of hydroxyurea and pipobroman in 292 patients under the age of 65 years. Blood. 1997;90:3370-3377. ... Pay-Per-View - Clinical Oncology Report - Factiva, from Dow Jones Annales de Biologie Clinique - Aug 27, 2005 à un traitement de fond cytoréducteur par, notamment, le phosphore 32 (P32) chez le sujet âgé, le pipobroman (Vercyte ® ) ou l'hydroxyurée (Hydréa ® ). ... john-libbey-eurotext.fr Brand Names/Synonyms: Pipobroman is also known by the following brand names and/or synonymsA 1803; A-8103; Amedel; NSC-25154; Pipobroman; Pipobroman [Usan:Inn]; Pipobromanum [Inn-Latin]; Vercyte Drug Category: Pipobroman is categorized under the following by the FDA: Antineoplastic Agents; ATC:L01AX02 Dosage Forms: TABLET (25 mg) Absorption: Well absorbed from the GI tract. Interactions: Not Available Chemical IUPAC Name: 3-bromo-1-[4-(3-bromopropanoyl)piperazin-1-yl]-propan-1-one |
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