Pravastatin

This page contains recent news articles, when available, and an overview of Pravastatin but does not offer medical advice. You should contact your physician with regard to any health issues or concerns.


Overview:

Pravastatin
(when available)

Pharmacology and use:
Pravastatin, an antilipemic agent, is used to treat primary hypercholesterolemia. Unlike lovastatin and simvastatin, pravastatin is relatively hydrophilic and does not require hydrolysis for activation. For the treatment of hypercholesterolemia to reduce the risk of myocardial infarction.

Mechanism Of Action:
Like lovastatin and simvastatin, pravastatin inhibits hydroxymethylglutaryl-CoA (HMG-CoA) reductase. As HMG-CoA is necessary for the intracellular synthesis of cholesterol, its inhibition results in increased clearance of circulating LDL. Pravastatin also inhibits hepatic synthesis of VLDL, the precursor for LDL, reducing circulating cholesterol and LDL cholesterol.

News Articles on Pravastatin

Clinical Trial: No  -  ‎Dec 11, 2009‎
Poisson regression analysis was performed to compare the number of occurrences of the primary endpoint between high-dose atorvastatin and pravastatin in the ... Cardiosource

Two Studies Show Prolonged Protective Effects of High-Dose Statins  -  ‎Dec 12, 2009‎
The current analysis found that subsequent cardiovascular events were reduced by 19% in the atorvastatin group compared with the pravastatin group (275 ... TCTMD

Intensive statin therapy linked with prevention of first occurrence of death ...  -  ‎Dec 15, 2009‎
They randomly assigned 4162 patients to receive either moderate lipid-lowering therapy with 40 mg pravastatin (Pravachol, Bristol-Meyers Squibb) or ... Cardiology Today

50 per cent Australians suffer from obesity, high BP  -  ‎Dec 11, 2009‎
Between 1995 and 2005 there was a 13-fold rise in the use of statins, with atorvastatin, simvastatin and pravastatin being the most common in 2007. ... TopNews United States

Eli Lilly Deal to Sell Livalo Not Without Risks  -  ‎Dec 28, 2009‎
...before approving a formulary change from one of the generically available statins (simvastatin, pravastatin, or lovastatin) to a branded-only statin. ... BNET

Lilly, Kowa and Kowa Pharmaceuticals America Announce Co-Promotion and ...  -  ‎Dec 26, 2009‎
The efficacy of LIVALO has been evaluated against atorvastatin, simvastatin, and pravastatin in patients with primary hyperlipidemia or mixed dyslipidemia. ... AUTO-MOBI.info

Modifiable Risk Factors For Heart Disease Identified By New Research  -  ‎Dec 14, 2009‎
...or revascularization) were reduced by 16 percent with atorvastatin 80 mg (intensive lipid lowering) versus pravastatin 40 mg (moderate lipid lowering) ... Medical News Today (press release)

Cross-breeding leading to native livestock decline in Orissa  -  ‎Dec 13, 2009‎
Oxytetracycline, Pergolide, Piroxicam, Pravastatin, Prochlorperazine, Spironolactone, Sulfasalazine, Sumatriptan, Terbinafine, Trifluoperazine. ... TopNews

Surgery not first approach to foot pain  -  14 Nov 2009
...a vitamin B12 injection once a month due to poor absorption, pravastatin for high cholesterol and Prevacid for gastroesophageal reflux disease (GERD). ... Telegraph-Journal

Statins Protect Against Parkinson's Progression in Mice  -  ‎Nov 2, 2009‎
Mice given the equivalent of standard simvastatin (Zocor) or pravastatin (Pravachol) doses lost fewer dopaminergic neurons and neurotransmitters, ... MedPage Today

UPI NewsTrack Health and Science News  -  ‎Nov 2, 2009‎
Pravastatin also increased the expression of another Alzheimer's hallmark, amyloid precursor protein. While increased levels of these two proteins may ... United Press International

What Risks Are Associated With High-Dose Rosuvastatin?  -  ‎Oct 22, 2009‎
...[1] Rosuvastatin is a potent statin, about twice as potent as atorvastatin, 4 times as potent as simvastatin, and at least 8 times as potent as pravastatin ... Medscape

Obesity and Survival Among Patients With Pancreatic Cancer  -  ‎Oct 27, 2009‎
Shepherd J, Blauw GJ, Murphy MB; et al, PROSPER study group; PROspective Study of Pravastatin in the Elderly at Risk. Pravastatin in elderly individuals at ... Journal of American Medical Association (subscription)

Statin drugs may lower deaths from flu: study  -  ‎Oct 29, 2009‎
Statin drugs include AstraZeneca's Crestor, known generically as rosuvastatin, Bristol-Myers Squibb Pravachol or pravastatin and Merck's Mevacor, ... Reuters

Crestor Reduces Lipids Better Than Pravachol in People With HIV  -  ‎Oct 27, 2009‎
Crestor (rosuvastatin) is better than Pravachol (pravastatin) in reducing triglycerides and low-density lipoprotein (LDL) levels—“bad� cholesterol levels—in ... AIDSmeds.com HIV/AIDS Treatment News

Red Yeast Rice and Hyperlipidemia: How Strong Is the Evidence?  -  ‎Oct 28, 2009‎
Fluvastatin and pravastatin may promote lower rates of rhabdomyolysis compared with other statins. There are wide-ranging estimates with regard to the ... Medscape

Rx copay cards: There's an easier way  -  ‎Nov 3, 2009‎
There are reasons that your physician may want you on atorvastatin instead of pravastatin or lovastatin. Not all medications are created equal. ... ModernMedicine

Open enrollment: Time for your own health care debate  -  ‎Oct 24, 2009‎
But it does have therapeutic equivalents -- simvastatin, lovastatin, pravastatin, according to health insurer AmeriHealth. Most insurance plans will have ... Hillsboro Argus - OregonLive.com

Parkinson: Cholesterinsenker stoppt Krankheit  -  ‎Nov 2, 2009‎
Die Neurologen testeten die Wirkung von Simvastatin und Pravastatin bei Mäusen, die nach einer chemischen Behandlung einen ähnlichen Krankheitsverlauf ... NetDoktor.de

Statin berpotensi sebabkan sakit otot  -  ‎Oct 25, 2009‎
Pasien pengguna simvastatin melaporkan efek samping paling banyak sedang pengguna pravastatin mengalami sakit otot paling ringan. ... Waspada Online

India Ranbaxy gets US FDA approval for pravastatin  -  Apr 25, 2007
MUMBAI, April 25 (Reuters) - Indian drug maker Ranbaxy Laboratories Ltd. (RANB.BO) said on Wednesday it had US Food and Drug Administration approval to ... Reuters

Barr's Pliva gets US FDA approval for 10mg, 20mg, 40mg Pravastatin …  -  Nov 28, 2006
The tablets are a generic version of Bristol-Myers Squibb's cholesterol-lowering agent Pravachol. Pliva also received tentative approval for its Pravastatin ... Forbes

India Glenmark gets US nod for pravastatin sodium  -  May 16, 2007
MUMBAI, May 16 (Reuters) - India's Glenmark Pharmaceuticals (GLEN.BO) said on Wednesday it had approval from the US Food and Drug Administration to sell ... Reuters

What's the evidence for statins for people with heart disease?  -  Nov 6, 2008
The study looked at two groups of people: some took the drug pravastatin while ... Effect of pravastatin on cardiovascular events and mortality in 1516 ... guardian.co.uk

Does pravastatin safely and effectively improve lipid profiles in...  -  Dec 8, 2005
Butani L (2005) Prospective monitoring of lipid profiles in children receiving pravastatin preemptively after renal transplantation. ... Nature.com

Statins cut risk of heart attack, but lifestyle changes still needed:...  -  Oct 10, 2007
One was given pravastatin, a drug that lowers LDL while increasing HDL, ... During the followup period, 619 study participants in the pravastatin group and ... CBC.ca

Amiodarone Interacts with Simvastatin but not with Pravastatin Disposi...  -  Nov 9, 2006
Effect of amiodarone on simvastatin and pravastatin pharmacokinetics. ... During period 1, the AUC 0–24 h of pravastatin did not differ between the subjects ... Nature.com

Ranbaxy gets nod to market Ran-Pravastatin in Canada  -  May 22, 2007
MUMBAI: Pharma major Ranbaxy Laboratories on Monday said that it has received approval from Canada's Therapeutic Products Directorate (TPD) to manufacture ... Hindu Business Line

… polypeptide 1B1 haplotype on pharmacokinetics of pravastatin,...  -  Aug 22, 2005
In each period, after a single oral administration of pravastatin, valsartan, ... In the case of valsartan we observed a similar trend as with pravastatin, ... Nature.com

… and sex affect the pharmacokinetics of pravastatin but not...  -  Jun 7, 2006
Objective: Pravastatin is a hydrophilic substrate and fluvastatin a ... Plasma fluvastatin and pravastatin concentrations were measured for 12 hours. ... Nature.com

Ranbaxy launches Pravastatin in US  -  Jun 26, 2007
New Delhi June 25 Two months after it finally received the go ahead from the US Food and Drug Administration, Ranbaxy has launched the 80 mg generic version ... Hindu Business Line

'Statins cut cholesterol and blood pressure'  -  Apr 15, 2008
A trial of 973 people between 2000 and 2004 compared those who took a placebo with those who took two types of statins - simvastatin and pravastatin. ... Telegraph.co.uk

Effect of pravastatin on blood pressure in people with cardiovascular...  -  Jan 17, 2006
Correspondence: Dr M Tonelli, Division of Nephrology, University of Alberta, 7-129 Clinical Science Building, 8440 112 Street, Edmonton, Alberta, Canada, ... Nature.com

Simvastatin, but Not Pravastatin, May Reduce Sleep Quality  -  Nov 8, 2007
The supporter had no role in selecting the study or interview sources for news coverage, and it did not review or approve the news article before ... Medscape

Ranbaxy locks horns with US FDA.  -  Nov 1, 2005
On October 21, the US court had ruled in favour of Teva's exclusivity for other strengths (10 mg, 20 mg, 40 mg) of Pravastatin tablets, as a result of which ... Free with registration - Economic Times - AccessMyLibrary.com

New Benefits From Old Heart Measures  -  Apr 14, 2008
It was a classic double-blind, controlled trial with some of the 973 participants taking either simvastatin (Zocor) or pravastatin (Pravachol), ... Washington Post

The pravastatin chance  -  Apr 25, 2006
The patent litigation scene in the US is becoming more and more interesting. The latest is about pravastatin, a cholesterol reducing blockbuster medication, ... Daily News & Analysis

Cadila gets US FDA approval  -  May 15, 2008
The US market of lipid lowering agent Pravastatin Sodium tablet was estimated at 1.9 million dollar in 2007, while the branded sales of anti-depressant ... Business Standard

Generic statins to shrink prices, brand power of cholesterol pills.  -  May 20, 2006
The third-most prescribed brand statin, Pravachol, became available as a cheaper generic, pravastatin, earlier this month. ... Free with registration - Chicago Tribune - AccessMyLibrary.com

Effects of Pravastatin on Obesity, Diabetes, and Adiponectin in Diet-...  -  Feb 21, 2007
The aim of this study was to investigate the in vivo effects of pravastatin on the development of obesity and diabetes in diet-induced obese (DIO) mice. ... Nature.com

Teva Announces Approval of Pravastatin Sodium Tablets, 80 Mg.  -  Jan 17, 2008
JERUSALEM -- Teva Pharmaceutical Industries Ltd. (Nasdaq: TEVA) announced today that the US Food and Drug Administration has granted final approval for the ... Free with registration - Business Wire - AccessMyLibrary.com

Prescribing old statins could help save £85m  -  Dec 28, 2006
However, prices differ significantly, with the older drugs simvastatin and pravastatin significantly cheaper than newer ones, such as atorvastatin (Lipitor) ... Times Online

Does reducing a patient's CRP levels with statin therapy reduce their...  -  Feb 7, 2005
This prospective analysis was part of the international, multicenter, randomized, double-blind Pravastatin or Atorvastatin Evaluation and Infection ... Nature.com

Teva Pharmaceuticals USA, Inc. v. Food & Drug Administration, 441...  -  Mar 16, 2006
In a letter to Teva and the other generic pravastatin sodium applicants, the FDA concluded that the Apotex "stipulation and order" qualified as a "decision ... $2.95 - U.S. Court of Appeals, District of... - VersusLaw

Pravastatin restores fat during protease inhibitor treatment  -  Nov 16, 2005
The lipid-lowering drug pravastatin produced significant gains in limb fat in HIV-positive people who received the drug during a small 12 week study, ... Aidsmap

Ranbaxy launches Pravastatin Sodium 80 mg tablets in USA, to benefit ...  -  Jun 25, 2007
Ranbaxy Laboratories Ltd on June 25, 2007, has announced that the Company's wholly owned subsidiary, Ranbaxy Pharmaceuticals Inc. (RPI), has launched ... Equity Bulls

Health Canada issues advisory over statins  -  Jul 14, 2005
Pravachol (pravastatin) and Crestor (rosuvastatin), put some patients with pre-existing medical conditions at greater risk of muscle-related problems. ... CTV.ca

Does pravastatin promote cancer in elderly patients? A meta-analysis.(...  -  Feb 27, 2007
Background: An increase in the incidence of cancer among elderly people assigned to pravastatin therapy has been reported in a randomized controlled trial; ... Free with registration - CMAJ: Canadian Medical Association... - AccessMyLibrary.com

Pravastatin prolongs graft survival in an allogeneic rat model of...  -  Sep 6, 2005
Yijiang Li a , Thorsten Köster a , Christiane Mörike a , Stephan v. Hörsten b , Ullrich Martin a , Michael Bader c , Axel Haverich a , Andre R. Simon a , * ... European Journal of Cardio-Thoracic...

Ranbaxy gets approval to market Ran-Pravastatin in Canada  -  May 21, 2007
Ranbaxy Laboratories Limited (RLL), announced today that the Company has received approval in Canada to manufacture and market Ran®-Pravastatin Tablets, ... Moneycontrol.com

Teva Announces Approval Of Pravastatin Sodium Tablets, 80 Mg  -  Jan 21, 2008
Teva Pharmaceutical Industries Ltd. (Nasdaq: TEVA) announced that the US Food and Drug Administration has granted final approval for the Company's ... Medical News Today - Medical News Today (press release)

Pravastatin slows kidney-function loss in CKD  -  Jul 18, 2005
Dallas, TX - Pravastatin slows the rate of kidney-function loss in patients with or at risk for cardiovascular disease (CVD), although its effect is modest ... Medscape

Pravastatin Increased Subcutaneous Fat in HIV-Infected Men  -  Aug 1, 2006
Twelve weeks of pravastatin therapy significantly increased subcutaneous fat and had limited effects on plasma lipid parameters. ... Medscape

Novartis unit sues Bristol, Watson  -  Jan 3, 2007
Lek owns two patents for crystalline forms of pravastatin, ... Lek claims that the Bristol-Myers version of the drug uses pravastatin in the forms covered ... Pay-Per-View - Los Angeles Times - ProQuest Archiver

Pravastatin 40mg TEVA vs Pravastatin 40mg APOTEK  -  Aug 11, 2008
For four years I have been taking Teva 40mg Pravastatin daily, with lipid panel tests every 90 days. All numbers dropped to normal/satisfactory levels. ... HealthCentral.com

Pravastatin Safe in Children With Hypercholesterolemia  -  May 10, 2005
A satisfactory reduction in total and LDL-cholesterol can be expected in those with slight or moderate but not severe hypercholesterolemia. ... Diabetes In Control

Pravastatin Is Cost-effective in High-Risk Patients  -  Nov 15, 2006
Clinical Question: What is the cost-effectiveness of pravastatin (Pravachol) treatment for patients at high risk of complications from high cholesterol who ... AAFP News Now

CV risk in diabetics with CKD  -  Oct 26, 2005
Investigators report that across all the subgroups, pravastatin reduced the relative ... Pravastatin reduced the absolute risk of MI, coronary death, CABG, ... Medscape

Sciele to Work on Fenofibrate and Pravastatin Combination  -  Feb 6, 2007
Sciele Pharma entered into an agreement with Galephar Pharmaceutical Research to develop and market a combination of fenofibrate and pravastatin to treat ... Genetic Engineering News - Genetic Engineering News (press release)

FDA Approves First Generic Pravastatin  -  Apr 24, 2006
The Food and Drug Administration today approved the first generic version of Bristol-Myers Squibb's Pravachol (Pravastatin Sodium Tablets), an important ... Pay-Per-View - U.S. Food & Drug Administration Documents - Factiva, from Dow Jones

Competitors by Product Report  -  Jul 19, 2008
IVAX Simvastatin; Lovastatin; Pravastatin Sodium; Simvastatin ... Andrx Pharmaceuticals Lovastatin; Pravastatin Sodium. Hyperlipidemia ... $75.00 - Revere Reports - Revere

Simvastatin, pravastatin may also lower blood pressure.(Cardiovascular...  -  Feb 15, 2005
NEW ORLEANS -- Treatment with either simvastatin or pravastatin led to significant reductions of both systolic and diastolic blood pressure that averaged ... Free with registration - Family Practice News - AccessMyLibrary.com

Par Pharmaceutical Begins Shipment of Pravastatin Tablets.  -  Oct 23, 2006
WOODCLIFF LAKE, NJ, Oct. 23 /PRNewswire-FirstCall/ -- Par Pharmaceutical Companies, Inc. today announced that it's partner, Genpharm Inc. of Toronto, ... $4.95 - PR Newswire - ECNext

Coming to a bad end: lost chromosome tips linked to heart problems.(Th...  -  Jan 20, 2007
Researchers randomly assigned them to receive pravastatin or a placebo. ... Regardless of their telomeres' lengths, men taking pravastatin developed heart ... $4.95 - Science News - ECNext

Pioglitazone and Major Adverse Cardiovascular Event in High-Risk …  -  Jun 9, 2008
Pravastatin in elderly individuals at risk of vascular disease (PROSPER): a ... Cardiovascular events and their reduction with pravastatin in diabetic and ... Medscape

Teva Comments on FDA Letter Regarding Pravastatin Exclusivity  -  Jul 6, 2005
Teva Pharmaceutical Industries Ltd. (Nasdaq: TEVA) announced today that it has received a letter from the US Food and Drug Administration ("FDA") concerning ... RedOrbit

Sankyo to Supply Hyperlipidemia Drug Pravastatin in US  -  Feb 20, 2006
Tokyo, Feb 20, 2006 (JCN) - Sankyo, a group company of Daiichi Sankyo, has announced its plan for pravastatin, a hyperlipidemia drug, in the US. ... japancorp.net

Statins May Simulate Stem Cells for Heart Repair  -  Nov 16, 2005
16, 2005 - The drug pravastatin, which is used widely to decrease high cholesterol ... Researchers at the University at Buffalo have found that pravastatin, ... SeniorJournal.com

Sankyo to Supply Hyperlipidemia Drug Pravastatin in US.  -  Feb 21, 2006
Tokyo, Japan, Feb 20, 2006 - (JCN) - Sankyo, a group company of Daiichi Sankyo, has announced its plan for pravastatin, a hyperlipidemia drug, in the US. ... Free with registration - JCNN News Summaries - AccessMyLibrary.com

Statin drugs may delay progressive artery damage in children  -  Aug 7, 2007
The children were randomized to receive the drug pravastatin or placebo for two ... At the end of the two years, the pravastatin-treated group continued ... News-Medical.net

Are the benefits of statins a class effect?  -  Apr 26, 2005
Fourth, the study was large enough to provide a precise estimate of the treatment effect (the 95% CIs are narrow and within a 10% range for pravastatin and ... CMAJ

Efficacy and Safety of Pravastatin in Children and Adolescents with …  -  Apr 10, 2007
Address all correspondence and requests for reprints to: Dr. Marjatta Antikainen, Hospital for Children and Adolescents, University of Helsinki, PO Box 281, ... Journal of Clinical Endocrinology and...

Acute Pravastatin Therapy Improves Clinical Outcomes After Aneurysmal...  -  Apr 27, 2006
April 27, 2006 (San Francisco) -- Immediate treatment of patients who have suffered an aneurysmal subarachnoid hemorrhage (SAH) with pravastatin for 14 days ... Medscape

… Pliva unit approval for generic pravastatin.(mergers and acquisitio...  -  Dec 4, 2006
Barr Pharmaceuticals says that its recently-acquired Croatian subsidiary Pliva (Marketletters passim) has received final approval from the US Food and Drug ... Free with registration - Pharma Marketletter - AccessMyLibrary.com

Impact of the SLCO1B1 polymorphism on the pharmacokinetics and lipid-...  -  Oct 13, 2005
Pravastatin pharmacokinetics and reduction in total and low-density lipoprotein ... Pravastatin significantly reduced the concentrations of total and LDL ... Nature.com

Sciele Pharma to test cholesterol drugs  -  Apr 18, 2007
The study will compare the combination of pravastatin and fenofibrate to pravastatin ... "Pravastatin already is a well-recognized statin that has been used ... Atlanta Business Chronicle

Maintenance therapies offer lasting heart health benefits  -  Mar 14, 2006
A total of 566 patients who received pravastatin therapy were evaluated in the ... Importantly, withdrawal of pravastatin led to a significant and rapid ... PsychCentral.com

Bentley Pharmaceuticals Provides Update on Product Approvals; …  -  Feb 27, 2006
Pravastatin is a cholesterol-reducing agent marketed by Bristol-Myers Squibb under the trade name of Pravachol(R). These approvals follow the acquisition of ... Free with registration - Business Wire - AccessMyLibrary.com

EBSCOhost Connection: Generic Pravastatin Approved.  -  Jul 1, 2006
FDA Consumer: The article reports on the approval of the first generic version of Bristol-Myers Squibb's Pravachol (pravastatin sodium) Tablets by the US ... Subscription - FDA Consumer - EBSCO Publishing

Sciele Enrolls Patients in Combination Pravastatin and Fenofibrate...  -  Oct 10, 2007
Sciele Pharma has completed enrollment of patients in a Phase III clinical trial using pravastatin and fenofibrate to treat mixed dyslipidemia. ... FDA news - FDA news (subscription)

Generic Pravastatin Sodium Tablets Approved  -  Dec 1, 2006
The FDA has approved PLIVA's ANDA to manufacture and market pravastatin sodium 10, 20, and 40 mg tablets, indicated for the primary prevention of coronary ... Facts and Comparisons

Press Release: Ranbaxy Launches Pravastatin Sodium 80 Mg Tablets. - …  -  Jun 25, 2007
Ranbaxy Launches Pravastatin Sodium 80 Mg Tablets. from PR Newswire. Highbeam Research – FREE Trial. Pay-Per-View - PR Newswire - HighBeam Research

… Subsidiary PLIVA Receives Approval for Pravastatin Tablets 10mg,...  -  Nov 28, 2006
Barr's Subsidiary PLIVA Receives Approval for Pravastatin Tablets 10mg, 20mg, and 40mg and Tentative Approval for 80mg. from PR Newswire. Pay-Per-View - PR Newswire - HighBeam Research

Statins and the Risk of Cancer—Reply  -  Jun 21, 2006
Pravastatin and rosuvastatin have low lipophilicity, atorvastatin and fluvastatin have ... 1 Pravastatin, fluvastatin, and atorvastatin do not penetrate the ... Journal of American Medical Association - Journal of American Medical Association...

Competitors by Product Report  -  Jul 19, 2008
IVAX Simvastatin; Lovastatin; Pravastatin Sodium; Simvastatin ... Andrx Pharmaceuticals Lovastatin; Pravastatin Sodium. Hyperlipidemia ... $75.00 - Revere - Alacra Store

… of primary and secondary prevention trials with lovastatin, pravast...  -  Sep 12, 2005
Although six statins are currently available, large clinical trials reported thus far have mainly evaluated atorvastatin, lovastatin, pravastatin, ... OnMedica

Effect of a Treatment Strategy Consisting of Pravastatin, Vitamin E,...  -  Jun 25, 2007
Prabath WB Nanayakkara, MD; Coen van Guldener, MD; Piet M. ter Wee, MD, PhD; Peter G. Scheffer, MD, PhD; Frans J. van Ittersum, MD, PhD; Jos W. Twisk, MD, ... Archives of Internal Medicine

Pravastatin.(NEW GENERICS)(Brief article)  -  Dec 11, 2006
Genpharm Inc., Toronto, (416) 236-2631, has been granted FDA approval to market pravastatin in 10-, 20-, and 40-mg tablets. ... Free with registration - Drug Topics - AccessMyLibrary.com

Statins Stop Hepatitis C Virus From Replicating  -  Jul 6, 2006
Using the OR6 cell culture assay system, they evaluated the anti-HCV activities of five statins: atorvastatin, fluvastatin, lovastatin, pravastatin and ... EndoNurse

Simvastatin, pravastatin may also lower blood pressure.(Cardiovascular...  -  Feb 15, 2005
Simvastatin, pravastatin may also lower blood pressure.(Cardiovascular Medicine) ... find Family Practice News articles. NEW ORLEANS -- Treatment with ... Pay-Per-View - Family Practice News - HighBeam Research

… : FDA approves first generic Pravastatin. - M2 Presswire | HighBeam...  -  Apr 25, 2006
FDA approves first generic Pravastatin. from M2 Presswire. Highbeam Research – FREE Trial. Pay-Per-View - M2 Presswire - HighBeam Research

… net profit leaps 11.2%, despite 1.4% sales decline on weak pravasta...  -  Jun 6, 2005
Revenues from pravastatin in Japan dropped 19.0% year-on-year to 82.5 billion yen, reflecting an 11% drug reimbursement price reduction on the drug and ... $4.95 - Pharma Marketletter - ECNext

Simvastatin, pravastatin lower blood pressure.(Cardiovascular...  -  Feb 1, 2005
Simvastatin, pravastatin lower blood pressure.(Cardiovascular Medicine) ... find Internal Medicine News articles. NEW ORLEANS -- Statins produce a small but ... Pay-Per-View - Internal Medicine News - HighBeam Research

Generic name: Pravastatin sodium  -  Dec 1, 2005
Pravachol is a cholesterol-lowering drug. Your doctor may prescribe it along with a cholesterol-lowering diet if your blood cholesterol level is dangerously ... Free with registration - PDR Family Guide to Prescription Drugs - AccessMyLibrary.com

The Peninsula On-line: Qatar's leading English Daily  -  Nov 9, 2007
Researchers at the University of California at San Diego who compared two types of cholesterol-lowering drugs called statins — simvastatin and pravastatin ... Peninsula On-line

… Shows that Availability of Generic Simvastatin and Pravastatin in...  -  May 17, 2006
WALTHAM, Mass., May 17 /PRNewswire/ -- Decision Resources, Inc., one of the world's leading research and advisory firms for pharmaceutical and health care ... Free with registration - PR Newswire - AccessMyLibrary.com

… Favorable Ruling from Japanese Patent Office Regarding Pravastatin.  -  Oct 14, 2005
Following a trial last August, the Patent Office found Sankyo's patent relating to pravastatin free of epipravastatin to be invalid based on prior ... $4.95 - Business Wire - ECNext

Generic pravastatin approved.(Bristol-Myers Squibb Co.'s Pravachol …  -  Jul 1, 2006
The FDA has approved the first genetic version of Bristol-Myers Squibb's Pravachol (pravastatin sodium) Tablets, an important step in the agency's effort to ... $4.95 - FDA Consumer - ECNext

Part 1: Comprehensive lipid-lowering update: how to get your high...  -  Feb 1, 2006
The Heart Protection Study (HPS) and the Pravastatin or Atorvastatin Evaluation ... (3) Treatment with standard therapy (pravastatin, 40 mg/d) or intensive ... Free with registration - Patient Care for the Nurse Practitioner - AccessMyLibrary.com

Pravastatin tablets.  -  Jan 22, 2007
Pravastatin tablets. Pliva Inc. has received approval for 10-, 20-, and 40mg pravastatin tablets, along with tentative approval for 80 mg. ... $9.94 - Drug Topics - Alacra Store

… : Watson Pharmaceuticals Launches Pravastatin Tablets. - PR...  -  Apr 25, 2006
Watson Pharmaceuticals Launches Pravastatin Tablets. from PR Newswire. Highbeam Research – FREE Trial. Pay-Per-View - PR Newswire - HighBeam Research

Par begins shipment of pravastatin tablets.(Industry News) | Article...  -  Nov 1, 2006
Par begins shipment of pravastatin tablets.(Industry News) ... find Pharmaceutical Processing articles. Par Pharmaceutical Companies, Inc. has announced ... Pay-Per-View - Pharmaceutical Processing - HighBeam Research

… Approval to Manufacture and Market Pravastatin Sodium Tablets in...  -  Apr 25, 2007
Ranbaxy Receives Approval to Manufacture and Market Pravastatin Sodium Tablets in US from PR Newswire. Highbeam Research – FREE Trial. Pay-Per-View - PR Newswire - HighBeam Research

… Pharmaceutical Begins Shipment of Pravastatin Tablets. - PR...  -  Oct 23, 2006
Par Pharmaceutical Begins Shipment of Pravastatin Tablets. from PR Newswire. Highbeam Research – FREE Trial. Pay-Per-View - PR Newswire - HighBeam Research

Statins Have Neutral Effect On Risk Of Cancer  -  Jan 5, 2006
The authors continue, "... the patients in our meta-analysis were primarily treated with simvastatin and pravastatin. As such, we evaluated pravastatin ... sciencedaily.com

NHS Could Save Millions Through Smarter Prescribing Of Cholesterol- …  -  Jan 2, 2007
They show that if every PCT prescribed pravastatin and simvastatin in 69 per cent of cases - the level achieved by the top quarter of trusts - then over ... Medical News Today - Medical News Today (press release)

Ranbaxy locks horns with US FDA. | Article from Economic Times (New …  -  Nov 1, 2005
On October 21, the US court had ruled in favour of Teva's exclusivity for other strengths (10 mg, 20 mg, 40 mg) of Pravastatin tablets, as a result of which ... Pay-Per-View - Economic Times - HighBeam Research

Pravastatin.(NEW GENERICS)(Brief article)  -  Dec 11, 2006
Genpharm Inc., Toronto, (416) 236-2631, has been granted FDA approval to market pravastatin in 10-, 20-, and 40-mg tablets. $4.95 - Drug Topics - ECNext

Article: Teva to start Pravastatin sales following US Appeals Court...  -  Apr 16, 2006
Teva to start Pravastatin sales following US Appeals Court ruling. ... find Globes (Tel Aviv, Israel) articles. Byline: Gitit Pincas Apr. 16--The saga of ... Pay-Per-View - Globes - HighBeam Research

… lowering.(Cardiovascular Medicine)(Pravastatin or Atorvastatin...  -  Sep 15, 2005
Cardiovascular Medicine)(Pravastatin or Atorvastatin Evaluation and Infection Therapy--Thrombolysis in Myocardial Infarction 22 trial) ... find Family ... Pay-Per-View - Family Practice News - HighBeam Research

New and generic drug approvals: Pravastatin Sodium Tablets. [3 tables...  -  Oct 25, 2006
On 25 Oct 2006, the US Food and Drug Administration announced approval of ANDA 076714 for Pravastatin Sodium Tablets. The product contains pravastatin ... Pay-Per-View - US Food and Drug Administration News - Factiva, from Dow Jones

Pravastatin.  -  Dec 11, 2006
Pravastatin. Genpharm Inc., Toronto, (416) 236-2631, has been granted FDA approval to market pravastatin in 10-, 20-, and 40-mg tablets. ... $9.94 - Drug Topics - Alacra Store

Ranbaxy to launch 15 drugs in US  -  Nov 19, 2005
Pravastatin 80 mg and Simvastatin 80 mg, both cholesterol drugs, and Modafinil which is used to treat sleep disorder. Pravastatin's market size is estimated ... Calcutta Telegraph

Statins keep trucking well  -  Oct 30, 2007
At an average follow-up of nearly 15 years from the study's outset, those who had taken pravastatin for the first five years then quit were still benefiting ... National Review of Medicine

Statin May Be Keeping You Up at Night  -  Nov 9, 2007
While pravastatin is soluble only in water, simvastatin is soluble in fat, and that allows the drug to more readily penetrate the cells and travel across ... Ivanhoe Broadcast News

Teva: Court wins favorable generic Pravachol court ruling.  -  Oct 21, 2005
...generic Pravastatin sodium tablets until the company's "180-day exclusivity" expires. The company plans to launch Pravastatin sodium tablets in April 2006. Free with registration - America's Intelligence Wire - AccessMyLibrary.com

BRIEFING - ASIA HEALTH - MAY 22, 2007.  -  May 22, 2007
The approval for tablets, in multiple dosages of 10 mg, 20 mg, and 40 mg, would open up the market for Pravastatin in Canada, which is valued at 72.9 ... Free with registration - AsiaPulse News - AccessMyLibrary.com

Loislaw Federal District Court Opinions - TEVA PHARMACEUTICALS …  -  Oct 21, 2005
The '227 patent, expiring on April 20, 2006, claims the pravastatin compound ... Teva never began marketing generic pravastatin. See Admin. Rec. Exh. 11. ... Pay-Per-View - Loislaw Federal District Court Opinions - Loislaw

… CRP, look beyond LDL lowering.(Cardiovascular Medicine)(Pravastatin...  -  Sep 15, 2005
That's the most common question that Christopher P. Cannon, MD, has fielded from physicians since he presented the findings of the landmark Pravastatin or ... Pay-Per-View - Family Practice News - Factiva, from Dow Jones

cmaj.ca -- eLetters for Brophy, 176 (5) 646-647  -  Mar 23, 2007
Title: Pravastatin and cancer in the elderly: Need for individual patient data ... Our meta-analysis encompassed 12 trials of pravastatin in a total ... CMAJ

Brand Names/Synonyms:
Pravastatin is also known by the following brand names and/or synonymsCCRIS 7557; Compactin; Elisor; Lipostat; Lovastatin; Mevalotin; Mevastatin; Mevinolin; Oliprevin; Pravachol; Pravaselect; Pravastatin; Pravastatin Sodium; Pravastatina [Spanish]; Pravastatine [French]; Pravastatinum [Latin]; Selectin; Selipran; Vasten

Drug Category:
Pravastatin is categorized under the following by the FDA: Anticholesteremic Agents; HMG-CoA Reductase Inhibitors; ATC:C10AA03

Dosage Forms:
TABLET

Absorption:
Average oral absorption of pravastatin is 34% and absolute bioavailability is 17%.

Interactions:
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Chemical IUPAC Name:
3,5-dihydroxy-7-[6-hydroxy-2-methyl-8-(2-methylbutanoyloxy)-1,2,6,7,8,8a-hexahydronaphthalen-1-yl]-heptanoicacid





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