Premarin

This page contains recent news articles, when available, and an overview of Premarin but does not offer medical advice. You should contact your physician with regard to any health issues or concerns.


Overview:

Premarin
(when available)

Pharmacology and use:
Conjugated estrogens, a mixture of the water soluble salts of sulfate esters from estrone, equilin, 17 α-dihydroequilin, and other related steroids, may be derived from pregnant equine urine or yam and soy plants. Estrogens are important in the development and maintenance of the female reproductive system and secondary sex characteristics. They promote growth and development of the vagina, uterus, and fallopian tubes, and enlargement of the breasts. Indirectly, they contribute to the shaping of the skeleton, maintenance of tone and elasticity of urogenital structures, changes in the epiphyses of the long bones that allow for the pubertal growth spurt and its termination, growth of axillary and pubic hair, and pigmentation of the nipples and genitals. Decline of estrogenic activity at the end of the menstrual cycle can bring on menstruation, although the cessation of progesterone secretion is the most important factor in the mature ovulatory cycle. However, in the preovulatory or nonovulatory cycle, estrogen is the primary determinant in the onset of menstruation. Estrogens also affect the release of pituitary gonadotropins. The pharmacologic effects of conjugated estrogens are similar to those of endogenous estrogens. For the treatment of moderate to severe vasomotor symptoms associated with the menopause, atrophic vaginitis, osteoporosis, hypoestrogenism due to hypogonadism, castration, primary ovarian failure, breast cancer (for palliation only), and Advanced androgen-dependent carcinoma of the prostate (for palliation only)

Mechanism Of Action:
Estrogens enter the cells of responsive tissues (e.g., female organs, breasts, hypothalamus, pituitary) where they interact with a protein receptor, subsequently increasing the rate of synthesis of DNA, RNA, and some proteins. Estrogens decrease the secretion of gonadotropin-releasing hormone by the hypothalamus, reducing the secretion of follicle-stimulating hormone (FSH) and luteinizing hormone (LH) from the pituitary.

News Articles on Conjugated Estrogens

Manassas Park woman sues drug company over breast cancer  -  ‎Jan 2, 2010‎
She had been taking Premarin and Prempro, two hormone therapy drugs that have been under scrutiny for potentially causing breast cancer. ... Washington Post

Menopause, as Brought to You by Big Pharma  -  ‎Dec 12, 2009‎
A 1950s ad for Premarin, far left; a popular 1966 book that referred to menopause as though it were a disease that could be cured with hormones; ... New York Times

Menopause: Marketing Fear  -  ‎Dec 15, 2009‎
The book that put Premarin, the pregnant-horse-urine-derived hormone drug, on the map was Feminine Forever, written by gynecologist Dr. Robert A. Wilson in ... Huffington Post (blog)

Pfizer Unit Loses Bid to Dismiss British Columbia Drug Suit  -  ‎Dec 23, 2009‎
23 (Bloomberg) -- Pfizer Inc.'s Wyeth unit failed to persuade a British Columbia appeals court to dismiss a lawsuit alleging the menopause drug Premarin ... Bloomberg

Simon v. Wyeth Pharmaceuticals, Inc.  -  ‎Jan 1, 2010‎
6 As noted supra, none of Appellant's three gynecologists who prescribed Premarin, Provera, or Prempro advised her that taking these hormones increased her ... Leagle, Inc.

Dr. Lynne Shuster - False Advertising Casts a Shadow On Menopausal Hormone ...  -  ‎Dec 15, 2009‎
Drugs such as Premarin, an estrogen derived from the urine of female horses, were developed to treat the “menopausal disease,� creating massive profits for ... Vitals Spotlight

Foal-time job  -  ‎Dec 27, 2009‎
Beau is among thousands of unwanted Premarin foals across the country, a byproduct of the hormone replacement medicine made from pregnant mare urine. ... Middletown Press

Paxil Suits Cost Glaxosmithkline 1 Billion For Settlements  -  ‎Dec 14, 2009‎
Pfizer faces thousands of additional lawsuits over Premarin and other hormone therapies. Last month, the company was ordered to pay more than $100 million ... Portfolio.com (blog)

Wyeth Pharmaceuticals, a Subsidiary of Wyeth, Currently Known as Pfizer ...  -  ‎Dec 11, 2009‎
The workers are engaged in activities related to the production of various pharmaceutical products such as Rapaume Liquid, Effexor, Premarin IV, Premarin, ... Trading Markets (press release)

This Year, Get In the Mood Again, by Making Just a Few Simple Changes in Your ...  -  ‎Jan 4, 2010‎
This approach is not accomplished by prescribing previously popular synthetic hormones (such as the brand names Premarin or Prempro) that many recent ... PR Web (press release)

Credit Suisse, Galleon, DiPascali, UBS in Court News  -  ‎Dec 16, 2009‎
Until 1995, many patients combined Premarin, an estrogen-based drug made by Pfizer's Wyeth unit, with progestin-laden Provera, made by Upjohn, ... Bloomberg

Letter: Consider breast cancer prevention  -  ‎Dec 11, 2009‎
Hormone replacements such as Premarin and Prempro significantly increase breast cancer risks. There are non-drug methods for controlling hot flashes and ... The Daily News Online

Ladies, Pick Your Cancer  -  ‎Dec 17, 2009‎
For forty years women obligingly swallowed the “fly� of Premarin, a horse urine menopause drug manufactured by Wyeth, now Pfizer, until it was shown to ... The Epoch Times

Pfizer Units Win Dismissal of 23 Menopause Drug Suits  -  ‎Dec 16, 2009‎
...separate complaints they were diagnosed with breast cancer after being prescribed hormone therapy medications including Premarin, Prempro and Provera. ... Bloomberg

Pfizer extends medication giveaway for jobless  -  ‎Dec 10, 2009‎
Wyeth drugs added include the blockbuster antidepressant Effexor, and the menopause treatments Premarin and Prempro. A Pfizer spokesman said in May the ... The Associated Press

23 Hormone Replacement Therapy Breast Cancer Lawsuits Dismissed  -  ‎Dec 18, 2009‎
...for Pfizer to dismiss the 23 lawsuits brought by women who alleged problems with hormone replacement therapy (HRT) drugs Prempro, Premarin and Provera. ... AboutLawsuits.com

Horse Heros: Group rescues mistreated horses  -  ‎Dec 23, 2009‎
..."When we were taking in Premarin horses from Canada, we would get up to 30 horses at a time. So, 64 from one location was quite different for us, ... Sulphur Springs Country World News

Pfizer Jury Said to Set Prempro Punitive Damages at $8 Million  -  ‎Dec 22, 2009‎
Until 1995, many patients combined Premarin, an estrogen- based drug made by Wyeth, with progestin-laden Provera, made by Upjohn, another subsidiary of ... Bloomberg

Pastile pentru menopauză, vinovate pentru cancer  -  ‎Dec 15, 2009‎
Prempro are la bază un alt medicament cu estrogen - Premarin, derivat din urina iepelor gestante, aprobat încă din 1942 de autorităţile americane. ... Gândul

I guai di Pfizer  -  ‎Dec 14, 2009‎
Negli Stati Uniti sono oltre diecimila le denunce di donne colpite da cancro al seno, dopo aver utilizzato i farmaci Prempro e Premarin, prodotti da Wyeth, ... RSI news

éš?处å?¯è§?的雌激素  -  ‎Dec 24, 2009‎
...常è§?çš„å?ˆæˆ?激素替代è?¯ç‰©åŒ…括å€?美力(Premarin)ã€?å€?美安(Prempro)ã€?酯化雌激素制剂(Menest)ã€?奥索雌酮片剂(Ortho-Est)ã€?雌二醇(Femhrt)ã€?炔诺酮(Activella) ... 腾讯网 (博客)

New damages trial for Wyeth in Ark. hormones case  -  ‎Nov 2, 2009‎
Jurors said Wyeth inadequately warned Scroggin that drugs Premarin and Prempro carried an increased risk of breast cancer. The suit also involved Upjohn's ... The Associated Press

Treat moderate to severe dryness, itching, and burning, in and around the vagina  -  ‎Nov 11, 2009‎
In general, you can expect relief from your moderate to severe menopausal symptoms to begin quickly with Premarin. You may begin to feel relief from hot ... Pattaya Daily News

Hidreth: The Unity of the Inner Man: digestion and assimilation  -  ‎Nov 9, 2009‎
This is why Premarin got into so much trouble as was shown in the great study that was done in Women's Initiative in 2002. This study, as, of course, ... Green Valley News

Pfizer in court again, this time for Wyeth's menopause treatment Prempro  -  ‎Oct 27, 2009‎
The drug, Prempro, from Pfizer's unit Wyeth, is a combination of hormones estrogen-progestin (Premarin and Provera) and is taken as a menopause treatment. ... Daily Finance (blog)

Bioidenticals are safe  -  ‎Nov 5, 2009‎
Premarin (8 conjugated equine hormones) and Provera (a synthetic progestin) were proven in a trial of 10000 women to increase heart attack, stroke, ... Helena Independent Record

Wine, auction benefit for Equine Voices this Sunday  -  ‎Oct 27, 2009‎
Many of the horses brought here by Pomroy are Premarin mares and their foals. Premarin is an artificial estrogen used for treating symptoms of menopause. ... Explorer News

Charities rally to save horses used in drug production  -  ‎Oct 25, 2009‎
Horse charities in North America have rallied in a bid to save more than 400 horses used in the production of the drug, Premarin, from slaughter. ... Horsetalk

Hormone Therapy Victims Win Important Appeal  -  ‎Nov 11, 2009‎
Donna Scroggin took Wyeth's Premarin (estrogen) and Pfizer-subsidiary, Upjohn's Provera (progestin). She then took Wyeth's Prempro, which combined estrogen ... Trading Markets (press release)

Birth control drugs and breast cancer  -  ‎Nov 6, 2009‎
4: Hormone replacement therapy sales of Premarin and Prempo dropped by 60 percent in 2002, when the National Women's Health Initiative showed that HRT drugs ... Gloucester Daily Times

10 Outrageous Menstrual Facts That'll Freak You Out  -  ‎Nov 10, 2009‎
Premarin is a synthetic estrogen product extracted from pregnant mares' urine, or “PMU.� Since more than nine million women in the United States take it, ... The Frisky

Bioidentical Hormones, a True Prevention for Breast Cancer  -  ‎Oct 21, 2009‎
Free radicals; Insulin resistance; Melatonin; Premarin; Progesterone; SHBG; vitamin D. Some will be covered by Dr. Khalid Mahmud as the Special Guest; ... Reuters

Zimmerman: Who can we trust if FDA puts stamp on snake oil?  -  ‎Nov 8, 2009‎
But they were written by hired hands of Wyeth, which benefitted to the tune of almost $2 billion on sales of Premarin and Prempro. In 2001, a big, ... Longview Daily News

Equine therapy helps teens' lives begin to blossom  -  ‎Oct 28, 2009‎
...and Sadie had been used by drug companies to extract her urine, a controversial practice used to develop the hormone replacement therapy drug Premarin. ... Local IQ

Think Disease Mongering Started with Consumer Ads?  -  ‎Oct 21, 2009‎
Since 85 percent of women said you want us to take WHAT and dropped HRT, closing Wyeth plants and hopefully Premarin ranches, pharma has scrambled to ... Scoop.co.nz

Pfizer Jury Said to Award $75 Million Prempro Verdict to Woman  -  ‎Nov 4, 2009‎
Until 1995, many patients combined Premarin, Wyeth's estrogen-based drug, with progestin-laden Provera, made by Upjohn, another Pfizer unit. ... Bloomberg

Business news in brief  -  ‎Nov 3, 2009‎
Jurors said Wyeth, which has operations in the Philadelphia area, inadequately warned Scroggin that drugs Premarin and Prempro carried an increased risk of ... Philadelphia Inquirer

奇美醫學中心研究 雌激素腦創傷有療效  -  ‎Oct 20, 2009‎
...雌激素(Premarin)原使用在å?œç¶“或更年期婦女的è?·çˆ¾è’™è£œå……療法上,但奇美醫學中心今天公布最新研究,Premarin也能用於腦創傷治療,具抗發炎ã€?抗細胞凋亡å?Šä¿?護腦神經 ... 聯合新聞網

Hormone Patches Safer Than Pills in Treating Menopause, Study Finds  -  Feb 25, 2007
The study tested Wyeth's Prempro and Premarin, which contain synthetic ... Before the Women's Health study, Prempro and Premarin accounted for half of the ... FOXNews

Legal Questions Still Dogging Wyeth  -  Jul 21, 2008
Prempro and Premphase contain both, while Premarin contains estrogen. ... Because the Premarin family of drugs remains on the market, lawsuits against Wyeth ... TheStreet.com - TheStreet.com (subscription)

Article: Wyeth closing plant due to poor Premarin sales  -  Oct 12, 2005
By The Record's staff. Drug maker Wyeth said Tuesday it will close its plant in Rouses Point, NY, due to declining sales of its hormone replacement drug ... Pay-Per-View - The Record - HighBeam Research

Brand-Name Drug Prices Up 7.1% in '04, Study Says  -  Apr 13, 2005
Wyeth's 26% increase on its Premarin menopause treatment was the biggest ... "We're committed to research in women's health, plus demand for Premarin is ... Pay-Per-View - Los Angeles Times - ProQuest Archiver

Homegrown Hormone Therapy: How Safe?  -  Jun 19, 2006
Annual sales of the Premarin family of drugs shriveled in the wake of ... Wyeth is now fighting 4500 personal injury cases related to Premarin and Prempro. ... BusinessWeek

Estrogen and your heart: Does it help or hurt?  -  Nov 15, 2005
When Premarin and synthetic progestin (MPA or Provera) was given to half of ... Was it the Premarin (Prem) or the Provera (Pro) that was to blame for some ... msnbc.com

Wyeth's Court Win a Good Sign  -  Sep 18, 2006
However, so far, Wyeth hasn't set up a reserve for liabilities for Prempro and Premarin. The hormone therapy drugs remain on the market. ... TheStreet.com - TheStreet.com (subscription)

Wyeth appeals $58M award in Nevada case  -  Mar 7, 2008
All involve the drugs Premarin, an estrogen replacement, and Prempro, a combination of estrogen and progestin. The drugs are prescribed to women to ease ... Forbes

Wyeth jury awards $99 mln punitive damages  -  Oct 15, 2007
The drugs, Premarin and Prempro, remain available on the US market. The Reno case is the seventh to reach a verdict since trials began in the hormone ... Reuters

Wyeth latest drugmaker to narrow focus of research  -  Oct 29, 2008
Norplant, Premarin and Prempro all triggered numerous lawsuits against the company. Wyeth will continue with late-stage testing of three experimental drugs ... FOXNews

After menopause, estrogen pills have little effect  -  Sep 26, 2005
Later results showed estrogen-only pills, sold as Premarin, slightly increased older women's risk of a stroke and possibly dementia. ... msnbc.com

Jury Awards $134.5 Million in Wyeth Hormone Drug Case  -  Oct 12, 2007
During the trial concluded here, the women testified that they had started taking Premarin, an estrogen replacement, and Prempro, a combination of estrogen ... New York Times

Wyeth Wins Breast Cancer Suit  -  Sep 15, 2006
She initially took Premarin, a form of estrogen, and her doctor soon added progestin to her daily regimen. She switched to Prempro in 1996, which for the ... CBS News

Wyeth Loses Suit Involving Its Hormone Drug  -  Feb 26, 2008
All the cases involve the drugs Premarin, an estrogen replacement, and Prempro, a combination of estrogen and progestin. Both drugs remain on the market and ... New York Times

Wyeth wins Arkansas hormone replacement trial  -  Feb 15, 2007
...also found that Wyeth was not negligent in its promotion of the drugs, Prempro and Premarin, and that plaintiff Helene Rush, 72, should have known about ... Reuters

Ark. woman says she didn't read Prempro risks, trusted doctor  -  Sep 1, 2006
Pruitt showed Reeves a label for Premarin that mentioned breast cancer as a risk of ... “If you had read that label in 1991, would you have taken Premarin? ... San Diego Union - Tribune - San Diego Union Tribune

Reno Jury Orders Wyeth to Pay $134 Million in Premarin Case  -  Oct 12, 2007
Pharmaceutical company Wyeth was ordered to pay three women about $43 million each, after a jury found the company liable for the women's cancer. ... Buzzle

Celebrity Drug Ads Avoid Mentioning Risks  -  Jul 19, 2005
The site is sponsored by Wyeth (search), maker of leading hormone replacement pills Prempro (search) and Premarin (search), and Wyeth's logo appears in the ... FOXNews

Blog this on:  -  Apr 17, 2006
Two years later, the estrogen-only (Premarin) part of the trial, which focused on nearly 11000 postmenopausal women who had undergone a hysterectomy, ... TIME

Judge dismisses two lawsuits against Wyeth  -  Jul 14, 2008
The plaintiffs in both cases claimed that their breast cancer was caused by their use of Wyeth's Prempro and Premarin hormone therapy products. ... Reuters UK

Wyeth Told Prempro Studies May Embarrass Drugmaker  -  Aug 26, 2006
Premarin contains estrogen and Prempro combines that hormone with another, progestin. ... Reeves was among as many as 6 million women who took Premarin and ... Bloomberg

Wyeth's First Non-Hormone Menopause Pill May Be Safer  -  Jul 23, 2007
Sales slowed for Wyeth's hormone-based menopausal treatments, Premarin and Prempro, ... US prescriptions for Premarin and Prempro, which contain two female ... Bloomberg

Premarin & Prempro Re-Classified 'Carcinogenic To Humans'  -  Jul 31, 2005
By DL McCracken. The World Health Organization's announcement that their International Agency for Research on Cancer division has re-classified Hormone ... halifaxlive.com

FDA Approves Low-dose Regimen Of Premarin Vaginal Cream To Treat …  -  Nov 15, 2008
PREMARIN® (conjugated estrogens) Vaginal Cream 0.5 g has been approved by the US Food and Drug Administration (FDA) for a new indication and a new less ... Medical News Today - Medical News Today (press release)

Cancer Claim Is Dismissed Against Wyeth Hormone Drugs  -  Oct 31, 2007
Wyeth, the largest maker of hormone-replacement medicines used during menopause, won dismissal of a lawsuit in Minnesota linking its Premarin and Prempro ... New York Times

Ruling prompts Barr to drop generic Premarin application | Article...  -  Jan 26, 2005
Ruling prompts Barr to drop generic Premarin application ... find The Record (Bergen County, NJ) articles. SUSAN DECKER, Bloomberg News The Record (Bergen ... Pay-Per-View - The Record - HighBeam Research

Jury orders $27M award in hormone suit  -  Mar 6, 2008
All the cases involve the drugs Premarin, an estrogen replacement, and Prempro, a combination of estrogen and progestin. Both drugs remain on the market and ... Boston Globe

Wyeth Beats Profit Targets  -  Apr 21, 2006
Sales of the Premarin family of products for treating menopause symptoms rose 26% to $266 million. However, that comparison was affected by wholesalers ... TheStreet.com - TheStreet.com (subscription)

Wyeth Cuts Sales Force, Doctor Visits  -  Jun 20, 2005
...drugs as anti-depressant Effexor (search), Protinix (search) for ulcers and Premarin (search) to prevent osteoporosis and treat symptoms of menopause. ... FOXNews

Wyeth Turns to Menopause Pills After Hormone Debacle  -  May 3, 2007
Sales of Wyeth's Premarin and Prempro hormones evaporated after a US study in 2002 ... US prescriptions for Premarin and Prempro, which contain two female ... Bloomberg

Premarin 90 Pills X 0.625 Mg  -  Jun 18, 2007
...medication. In the United States, the main body Premarin 90 Pills X 0.625 Mg regulates pharmaceuticals is the Food and Drug Administration and they enforce ... Sokwanele

Wyeth will seek OK for 7 drugs in next 18 months  -  Oct 6, 2006
Wyeth also needs to make up for revenue lost since its Premarin hormone drugs were linked to cancer and heart risks in 2002. ... Boston Globe

Wyeth, Pfizer Ordered to Pay $27 Million in Punitives  -  Mar 6, 2008
Wyeth has lost four of seven cases over Premarin and Prempro since they began going to ... Until 1996, some menopausal women used Premarin, which contained ... Bloomberg

Wyeth says wins Philadelphia hormone therapy trial  -  May 15, 2007
Wyeth faces some 5000 lawsuits over HRT drugs Premarin and Prempro. The drugs remain on the market, even though a major government-sponsored health study ... Reuters

New Evidence Linking Premarin to Breast Cancer Will Spike Number of …  -  Dec 20, 2006
SACRAMENTO, Calif., Dec. 20 /PRNewswire-USNewswire/ -- According to a leading animal advocacy and rescue group, thousands of pregnant horses used on hormone ... Free with registration - PR Newswire - AccessMyLibrary.com

… ON PETA RESOLUTION TO END PREMARIN PROMOTION AND RETIRE …  -  Apr 20, 2005
The pregnant mares used in the production of Premarin (whose name derives ... Sales of Premarin and related products have seen a dramatic decrease in market ... peta.org

FDA Approves Low-Dose Regimen of PREMARIN Vaginal Cream to Treat …  -  Nov 13, 2008
COLLEGEVILLE, Pa., Nov. 13 /PRNewswire-FirstCall/ -- PREMARIN(R) (conjugated estrogens) Vaginal Cream 0.5 g has been approved by the US Food and Drug ... RedOrbit

Drug Maker Shares Breast Cancer Survivor's Pain  -  Oct 16, 2007
Rowatt followed her doctors' orders and took Premarin, and then Prempro, to ease the symptoms of menopuase for nearly eight years. ... ABC News

Premarin derived from mare urine, maker tells jurors Wyeth division …  -  Aug 25, 2006
BY LINDA SATTER ARKANSAS DEMOCRAT-GAZETTE. A Wyeth Pharmaceuticals president acknowledged Thursday from the witness stand that its estrogen-only drug, ... Pay-Per-View - Arkansas Democrat Gazette - Factiva, from Dow Jones

New Data Show Most Postmenopausal Women in Study Who Initiated …  -  Mar 24, 2005
The Women's HOPE Study evaluated four low dose options: Premarin 0.3 mg, PREMARIN 0.45 mg, Prempro 0.3 mg/1.5 mg, and PREMPRO 0.45 mg/1.5 mg. ... Free with registration - PR Newswire - AccessMyLibrary.com

BC court clears path for HRT class-action suit  -  Jun 30, 2008
Stanway alleges she got breast cancer after taking Premarin. The drug's maker, Wyeth-Ayerst International, asked the court to dismiss the legal action, ... CTV.ca

Judge dismisses hormone case against Wyeth  -  Oct 30, 2007
...not offered any scientifically valid evidence to support her claim that she had developed breast cancer as a result using Wyeth's Premarin and Prempro. ... Reuters

Estrogen Alone Does Not Increase Risk of Breast Cancer  -  Apr 11, 2006
Moreover, women taking 0.625 mg/day of Premarin (conjugated equine estrogen) had ... These Premarin data emerged from the Women's Health Initiative (WHI) ... MedPage Today

New Data Show Most Postmenopausal Women in Study Who Initiated …  -  Mar 27, 2005
The Women's HOPE Study evaluated four low dose options: PREMARIN 0.3 mg, PREMARIN 0.45 mg, PREMPRO 0.3 mg/1.5 mg, and PREMPRO 0.45 mg/1.5 mg. ... i-newswire.com

51 Utahns pin cancer on drugs  -  Feb 12, 2007
The Utah women allege they took Prempro or Premarin alone or with Provera for ... That campaign helped make Premarin the most prescribed drug in the country ... $2.95 - Salt Lake Tribune, The - NewsBank

Judge cuts jury award in Wyeth suit  -  Feb 21, 2008
The women claimed Wyeth's hormone-therapy drugs Premarin and Prempro caused their breast cancer. They alleged Wyeth produced a dangerous product, ... United Press International

Press Release: New Evidence Linking Premarin to Breast Cancer Will …  -  Dec 20, 2006
New Evidence Linking Premarin to Breast Cancer Will Spike Number of Hormone Farm Horses in Need of Rescue in 2007, According to Leading Animal Advocacy and ... Pay-Per-View - PR Newswire - HighBeam Research

New menopause pill, Aprela, may reduce hot flashes  -  Oct 7, 2007
The company predicts sales of Aprela, if it's approved by regulators, will hit $2 billion a year - offsetting a plunge in revenue from the hormones Premarin ... New York Daily News

HRT, Breast Cancer, And Bioidentical Hormones  -  Aug 19, 2006
Premarin is one of the best well know, and oldest, types of hormone treatment. Premarin is made from the urine of pregnant horses, and is an estrogen only ... Buzzle

Appeals Court Rules in Favor of Wyeth in Premarin Case  -  Jan 31, 2005
Barr has elected to withdraw its pending abbreviated new drug application (ANDA) from the FDA for a generic version of Wyeth's Premarin, after a federal ... Pay-Per-View - Pharmaceutical Corporate Compliance... - Factiva, from Dow Jones

… : FDA Approves Low-dose Regimen of PREMARIN Vaginal Cream to …  -  Nov 13, 2008
FDA Approves Low-dose Regimen of PREMARIN Vaginal Cream to Treat Moderate to Severe Postmenopausal Dyspareunia - Painful Sexual Intercourse. from PR ... Pay-Per-View - PR Newswire - HighBeam Research

Generic Premarin  -  Aug 17, 2007
...* 7 Footnotes * 8 External links [edit] Medicine development and Generic Premarin testing * 2 Drug legislation and safety In the United States, ... Sokwanele

FDA Approves Low-dose Regimen of Premarin Vaginal Cream to Treat …  -  Nov 17, 2008
...(Nov 17, 2008)-- PREMARIN (conjugated estrogens) Vaginal Cream 0.5 g has been approved by the US Food and Drug Administration (FDA) for a new indication and ... Compliance Home - Compliance Home

Order Premarin  -  May 7, 2007
...include clinical pharmacology (the medical Order Premarin of medication is a licensed drug (chemical) taken to Order Premarin prevent or reduce symptoms of ... Sokwanele

Premarin' Prozac" klor-con Bextra" Zantac'  -  Apr 14, 2005
Last year, million Americans got their brand-name medications absolutely FREE! That's because they took advantage of "patient assistance programs," which ... Reading Eagle - Google News Archive

Lawyers say Wyeth drugs promoted cancer.  -  Sep 11, 2006
Premarin is a form of estrogen; its sister drug, Prempro, ... Reeves used either Premarin or Prempro for more than eight years before she was diagnosed with ... Free with registration - America's Intelligence Wire - AccessMyLibrary.com

Premarin and Prempro Heyday Finally Over  -  Mar 16, 2008
By Martha Rosenberg, AlterNet. Posted March 16, 2008. Juries and medical journals are making hormone replacement therapy-mongering increasingly difficult ... alternet.org

… HORSE LOVERS RESCUE FOALS RESULTING FROM PREMARIN …  -  Feb 5, 2005
Premarin, produced by extracting estrogens from pregnant mare urine, is marketed by ... Wyeth representatives didn't return phone calls to discuss Premarin ... $2.95 - Santa Rosa Press Democrat - NewsBank

Premarin Suit May Lead to New Opt-Out Rule  -  Jun 22, 2006
As Wyeth Pharmaceuticals defends itself against antitrust claims in San Francisco Superior Court, its legal battles may lead to a new rule for opting out of ... Law.com

Hormones seen less risky in patch or gel, Menopause study: Pills...  -  Feb 27, 2007
A spokesman for Wyeth, maker of the bestselling pills Premarin and Prempro, couldn't be reached for comment on the study, which came out on a holiday. ... Pay-Per-View - Newsday - ProQuest Archiver

Women Aged 50-59 Taking Oral Estrogen Therapy Had Reduced Levels …  -  Jun 21, 2007
PREMARIN and PREMPRO are the most widely prescribed hormone therapy products in ... What is the most important information you should know about PREMARIN ... Medical News Today - Medical News Today (press release)

DEAR PHARMACIST SUZY COHEN  -  Jan 13, 2005
And there's Premarin, a prescribed estrogen drug that comes from a pregnant horse's urine. Insulin, used to balance blood sugar, was extracted from pigs and ... Pay-Per-View - South Florida Sun - Sentinel - ProQuest Archiver

ESTROGEN AND CANCER RISK  -  Mar 20, 2008
The medications used in the study contained equine estrogen and synthetic progestins (i.e. Premarin, Prempro). A new JAMA study found that once women stop ... Pay-Per-View - South Florida Sun - Sentinel - ProQuest Archiver

… TO MARE BRED TO PRODUCE PREMARIN, HORSE ESCAPED SAME …  -  Mar 30, 2007
Hera, a dapple-gray mare who towers over her Healdsburg owner and groom, came to the Alexander Valley by chance, untamed and accustomed to running free on ... $2.95 - Santa Rosa Press Democrat - NewsBank

Study briefs, 7/18: Plantar fasciitis, estrogen, diabetes  -  Jul 17, 2006
...estrogen (Premarin) or a placebo daily. The women rated their hot flashes based on severity and frequency, creating a composite score. ... Lincoln Journal Star

Premarin: Hormone therapy hurts women, horses  -  Aug 12, 2007
Rejoice in those mood swings and night sweats, oh menopausal ones, because they sure beat the alternative. Hormone therapy increases breast cancer, stroke, ... Horsetalk

New Analysis Of Data From WHI Provides Reassurance With Respect To …  -  Apr 4, 2007
PREMARIN and PREMPRO are the most widely prescribed hormone therapy products in ... What is the most important information you should know about PREMARIN ... Medical News Today - Medical News Today (press release)

Breast cancer's decline  -  Apr 26, 2007
For years, many physicians encouraged women to take drugs like Premarin, Provera or Prempro as soon as they began having hot flashes. ... $2.95 - Buffalo News - NewsBank

Wyeth to close Premarin plant, declining sales to blame  -  Oct 21, 2005
Wyeth said that it plans to cease operations at its Premarin (conjugated estrogens tablets) manufacturing plant in Rouses Point, NY, because of declining ... PR Week - PRWeek

Homes Needed for Premarin Mares, Foals  -  Feb 12, 2007
An estimated 20000 pregnant mares on farms in the US and Canada are suddenly at risk as PMU ranches face closure. By Susan Morrison ... EquiSearch.com

Pegasus Foundation Sees Some Success In Premarin Horse Adoptions  -  Oct 18, 2006
WESTMORELAND COUNTY, Pa. -- It was a happy homecoming in Westmoreland County on Wednesday for two dozen horses. The premarin horses were adopted by local ... ThePittsburghChannel.com

Part two: Are Hormones Safe?  -  May 23, 2008
The WHI study researched the effects of Premarin and Provera on ... Now let's go back to Premarin. Why would our bodies convert equine estrones into the ... nwsource.com

Post-premarin syndrome  -  Dec 2, 2005
SISTERS, Ore. - Vickie Herring and Virginia Loomis have ridden to the rescue of more than 800 horses that were most likely headed to a slaughter plant. ... $2.95 - Capital Press - NewsBank

Premarin or the PMU  -  May 17, 2006
It is a horrible thing and whoever does it should go to jail. how would you like it if YOU were hooked to a harness and got pregnant all the time and then ... PetPeoplesPlace.com

PMU Foal Controversy  -  Sep 24, 2007
..."If people can be educated about the alternatives available to Premarin, ... Says Ralston, "The Premarin industry has been in place for over thirty years ... EquiSearch.com

Rapid Genital Atrophy After Stopping Estrogen  -  Oct 22, 2005
No study in the world has shown that the use of Premarin Cream has caused an ... Premarin cream increases the thickness of the tissues of the vaginal ... canadafreepress.com

Premarin story was a shocker  -  May 10, 2007
I am shocked by this story ("Sanctuary for equine rejects," May 3 East Side/Sahuarita Star, and May 7 in the Star). How on earth was such a product and ... Arizona Daily Star

Dr. Gott: Urinary issue calls for a second opinion  -  May 30, 2007
Dear Dr. Gott: Recently, you wrote about the use of Premarin as a vaginal ... Please discuss the use of Premarin further. I am very concerned and hope I'm ... Amarillo.com

RESCUE UNWANTED FOALS BY NOT TAKING PREMARIN  -  Apr 7, 2005
Kudos to Jennifer Swanson and Florida Foal Rescue for their work to help Premarin horses ("Foals' journey brings second shot at life," March 21). ... Pay-Per-View - Palm Beach Post - NewsBank

Are Natural Hormones Better?  -  Nov 14, 2005
My physician had me on Premarin for several years. We discussed the advantages and disadvantages of this treatment several times, and he assured me that ... HealthCentral.com

Synthetic vs. "bioidentical" hormones.  -  Nov 1, 2007
What they may or may not realize is that the doctor-recommended Premarin comes from ... Second, there are approximately 30 different estrogens in Premarin. ... Free with registration - Running & FitNews - AccessMyLibrary.com

Prostate Cancer in a Transgender Woman 41 Years After Initiation of …  -  Nov 15, 2006
She continued taking conjugated estrogen tablets (Premarin, 1.25 mg daily). After 6 weeks of treatment, her PSA level had decreased by 68%, ... Journal of American Medical Association - Journal of American Medical Association...

… HRT Portfolio Strategy - Preserving the Premarin Brand and...  -  Feb 2, 2005
Wyeth HRT portfolio strategy - preserving the Premarin brand and gambling on new molecules Premarin/Prempro Bazedoxifene and trimegestone ... $4.95 - Business Wire - ECNext

Can washing your hands spread germs?  -  Sep 20, 2005
My doctor pre scribed Premarin cream to solve this problem. ... Premarin cream contains, conjugated estrogens and has long been used to treat vaginal ... Tuscaloosa News - Google News Archive

Pharma to medical press: thanks for resuscitating HRT  -  Apr 14, 2007
...(Premarin, derived from pregnant mares urine, also harms horses who are hooked up to "pee lines" while their foals are sent to slaughter. ... OpEdNews

Wyeth site rescued by new start-up firm  -  Jan 16, 2008
The plant itself covers around one million square feet in manufacturing and packaging facilities, currently used to manufacture products such as Premarin ... OutSourcing-Pharma.com

Man's breast enlargement problem traced to wife .  -  Jul 4, 2005
I was using Premarin vaginal cream for vaginal dryness about three times a week. ... The question would be, does your wife use Premarin vaginal cream? ... Rock Hill Herald - Google News Archive

Illinois Administrative Code - 77 Ill. Adm. Code 2070.1984 Premarin...  -  Aug 10, 2005
77 Ill. Adm. Code 2070.1984 Premarin with Methyltestosterone Premarin with Methyltestosterone (Source: Added at 20 Ill. Reg. 3081, effective February 2, ... Pay-Per-View - Illinois Administrative Code - Loislaw

Wyeth to close further manufacturing facility on Premarin woes.  -  Oct 17, 2005
As a result of slowing sales of its once-leading hormone replacement product Premarin (conjugated estrogens), US drug major Wyeth is phasing out ... Pay-Per-View - Pharma Marketletter - Factiva, from Dow Jones

… to close further manufacturing facility on Premarin woes.(Brief...  -  Oct 17, 2005
As a result of slowing sales of its once-leading hormone replacement product Premarin (conjugated estrogens), US drug major Wyeth is phasing out ... $4.95 - Pharma Marketletter - ECNext

HRT breast cancer case thrown out of court  -  Nov 4, 2007
Patricia Zandi blames her use of the HRT drugs Premarin and Prempro for her breast cancer; the drugs are manufactured by drug company Wyeth. ... News-Medical.net

Federal appeals court upholds Wyeth's favorable verdict in Prempro...  -  Feb 14, 2008
Little Rock resident Helene Rush sued the hormone manufacturer in 2005, accusing the company of negligence in its Prempro and Premarin hormone therapy. ... Southeast Texas Record

HORMONE THERAPY CHANGING  -  Jul 14, 2005
For example, Premarin, the most widely used estrogen replacement for decades, is from the horse species, and is not identical to human estrogen. ... $2.95 - Sun Herald - NewsBank

Wyeth Settles 1st NJ Prempro Case  -  Jul 16, 2007
Maybe now the word will get out that Premarin/Prrempro the HRT's are unavoidably dangerous. breast cancers. Estrogen encourages breast cells to divide more ... Pharmalot

Loislaw Federal District Court Opinions - JBDL CORP. v. WYETH- …  -  Jun 13, 2005
Factual Background Wyeth manufactures Premarin. Premarin is Wyeth's trade name for its conjugated estrogen product approved for several therapeutic ... Pay-Per-View - Loislaw Federal District Court Opinions - Loislaw

Woman who won millions from Wyeth in cancer suit dies  -  Jun 22, 2008
...across the country in state and federal courts. All of the suits involve Prempro and Premarin, which are prescribed to women to ease symptoms of menopause. WBIR-TV

Is therapy best bet for pain in feet?  -  Dec 24, 2005
I visited my gynecologist, and he gave me Premarin vaginal cream for vaginal atrophy after asking a few questions about the health of my siblings. ... $2.95 - Erie Times-News - NewsBank

DEAR PHARMACIST .  -  Sep 29, 2006
In case you haven't heard, this study was stopped midway because too many women were suffering or dying. The landmark clinical trial used Premarin (horse ... Lodi News-Sentinel - Google News Archive

Jury rules for Wyeth in hormone lawsuit  -  Sep 20, 2006
Wyeth lawyers told jurors that the benefits of Prempro and a similar drug, Premarin, outweighed the risks and said the drug company had informed both Reeves ... Legalbrief - Legalbrief (subscription)

Anxious Employee: 'I Like My Wyeth Money'  -  Jun 21, 2007
...said they'd heard company operations in Ireland - where Rouses Point's Premarin production is being moved - were gearing up slower than expected. ... Pharmalot

Brand Names/Synonyms:
Premarin is also known by the following brand names and/or synonymsAUSTRIA; BELGIUM; BRAZIL; BULGARIA; CANADA; CHINA; COLOMBIA; COSTA-RICA; Conestoral; DENMARK; DOMINICAN-REPUBLIC; ECUADOR; EL-SALVADOR; ENGLAND; ESTRONE-SULFATE; Estrogens; Estrone Estrone Hydrogen Sulfate; Estrone Hydrogen Sulfate; Estrone Sodium Sulfate; Estrone Sulfate; Estrone Sulfate Sodium; Estrone Sulphate; Evex; FINLAND; FRANCE; GREECE; GUATEMALA; HONDURAS; HONG-KONG; HUNGARY; Hyhorin; INDIA; IRELAND; ITALY; JAPAN; KOREA; MALAYSIA; MEXICO; MIDDLEEAST; Morestin; NETHERLANDS; NEW-ZEALAND; NICARAGUA; Oestrone Sulphate; PANAMA; PERU; PHILIPPINES; PORTUGAL; Par Estro; Premarin; Prempro/Premphase; RUSSIA; SWITZERLAND; Sodium Estrone Sulfate; TAIWAN; THAILAND; TURKEY; URUGUAY; US

Drug Category:
Premarin is categorized under the following by the FDA: Estrogens; ATC:G03CA57

Dosage Forms:
Tablet; Injection; Vaginal Cream; Topical Gel

Absorption:
well absorbed

Interactions:
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Chemical IUPAC Name:
sodium 13-methyl-17-oxo-3-sulfonatooxy-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthrene





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