Prochlorperazine

This page contains recent news articles, when available, and an overview of Prochlorperazine but does not offer medical advice. You should contact your physician with regard to any health issues or concerns.


Overview:

Prochlorperazine
(when available)

Pharmacology and use:
Prochlorperazine, a piperazine phenothiazine related to high-potency neuroleptics such as perphenazine, is used as an antiemetic and antipsychotic agent in the management of nausea and vomiting. It shares many of the actions and adverse effects of the antipsychotics. For control of severe nausea and vomiting, also used in management of the manifestations of psychotic disorders

Mechanism Of Action:
Prochlorperazine blocks the D2 somatodendritic autoreceptor, resulting in the blockade of postsynaptic dopamine receptors in the mesolimbic system and an increased dopamine turnover. The antiemetic effects of prochlorperazine can be attributed to dopamine blockade in the chemoreceptor trigger zone. Prochlorperazine also blocks anticholinergic and alpha-adrenergic receptors, the blockade of alpha(1)-adrenergic receptors resulting in sedation, muscle relaxation, and hypotension.

News Articles on Prochlorperazine

Alexza Announces Submission of AZ-004 (Staccato(R) Loxapine) NDA  -  ‎Dec 14, 2009‎
Alexza has completed an end-of-Phase 2 meeting with the FDA for AZ-001 (Staccato prochlorperazine) and has completed two Phase 2 studies with AZ-104 ... CNNMoney.com (press release)

Cross-breeding leading to native livestock decline in Orissa  -  ‎Dec 13, 2009‎
Oxytetracycline, Pergolide, Piroxicam, Pravastatin, Prochlorperazine, Spironolactone, Sulfasalazine, Sumatriptan, Terbinafine, Trifluoperazine. ... TopNews

Alexza anuncia la presentación de la NDA de AZ-004 Loxapina)  -  ‎Dec 15, 2009‎
Alexza ha completado un encuentro de final de fase 2 con la FDA para AZ-001 (Staccato prochlorperazine) y ha completado dos estudios de fase 2 con AZ-104 ... Finanzas.com

Alexza gibt Einreichung einer NDA fur AZ-004 (Staccato(R) Loxapine) bekannt  -  ‎Dec 15, 2009‎
Alexza hat eine Besprechung zum Abschluss von Phase 2 fur AZ-001 (Staccato prochlorperazine) mit der FDA abgehalten sowie zwei Studien der Phase 2 mit ... PR-Inside.com (Pressemitteilung)

Alexza annonce la présentation de nouveau médicament concernant l'AZ-004 ...  -  ‎Dec 15, 2009‎
Alexza a tenu une rencontre de fin de la phase 2 avec la FDA concernant l'AZ-001 (Staccato prochlorperazine) et a réalisé deux études de phase 2 ... Capital.fr

Alexza to Announce 2009 Third Quarter Financial Results and Update Its AZ-004 ...  -  ‎Nov 2, 2009‎
Alexza has completed an end-of-Phase 2 meeting with the FDA for AZ-001 (Staccato prochlorperazine) and has completed two Phase 2 studies with AZ-104 ... Reuters

My brain abscess and me  -  ‎Nov 2, 2009‎
I pass the weekend in a miserable blur: dozing, sipping squash, swallowing grapes and prochlorperazine (tablets for dizziness and nausea), and then hurling ... guardian.co.uk

Before Prozac: The Troubled History of Mood Disorders in Psychiatry  -  ‎Nov 2, 2009‎
Maybe a combination drug like Eskatrol (dextroamphetamine and prochlorperazine), hair raising as it sounds, does have its place. ... Am J Psychiatry (subscription)

Alexza posts positive drug trial data; stock soars  -  Mar 26, 2007
Alexza said its lead product, a vaporized version of an old anti-nausea drug called prochlorperazine, reduced migraine pain by a statistically significant ... Reuters

In-vitro characterization of the metabolism of prochlorperazine  -  Aug 1, 2006
Background: Prochlorperazine (PCZ) is an antiemetic widely used in the management of nausea and vomiting. PCZ is reported to be extensively metabolized via ... Nature.com

Learn about Prochlorperazine from Consumer Reports Health.  -  Jan 11, 2008
Studies have shown that older adults with dementia (a brain disorder that affects the ability to ... Full Alert. Prochlorperazine suppositories and tablets ... consumerreports.org

How to take Prochlorperazine from Consumer Reports Health.  -  Jan 11, 2008
Studies have shown that older adults with dementia (a brain disorder that affects the ability to ... Full Alert. tell your doctor and pharmacist if you are ... consumerreports.org

The role of prochlorperazine.  -  Mar 12, 2005
Prochlorperazine is a very useful drug in the management of acute vertigenous symptoms. It is a vestibular seditive that can offer symptomatic relief of ... Free with registration - Pulse - AccessMyLibrary.com

Morrisville biotech files for federal approval of drug  -  May 2, 2005
The drug is a formulation of prochlorperazine, which already has been approved for the treatment of nausea and vomiting. BDSI (NASDAQ:BDSI) says its version ... Bizjournals.com

… - 21 CFR § 522.1920 Prochlorperazine, isopropamide for injection.  -  Jul 11, 2006
21 CFR § 522.1920 Prochlorperazine, isopropamide for injection. (a) Specifications. Prochlorperazine, isopropamide for injection, veterinary, ... Pay-Per-View - United States Code of Federal Regulation... - Loislaw

Prochlorperazine Side Effects from Consumer Reports Health.  -  Jan 11, 2008
Studies have shown that older adults with dementia (a brain disorder that affects the ability to ... Full Alert. Studies have shown that older adults with ... consumerreports.org

Alexza's AZ-001 Phase IIb Trial Meets Primary Endpoint of 2-Hour Pain...  -  Mar 25, 2007
..."Prochlorperazine has long been administered intravenously with significant success ... In the trial, three doses of AZ-001 (Staccato prochlorperazine in 5, ... Genetic Engineering News - Genetic Engineering News (press release)

… Drug; Caution must be paid with the use of prochlorperazine  -  Apr 4, 2005
..."Thus, caution has to be paid on the use of prochlorperazine particularly for patients ... Keywords: Yamanashi, Japan, Prochlorperazine, Antipsychotic Drug, ... Pay-Per-View - Cardiovascular Week - Factiva, from Dow Jones

… Drug; Caution must be paid with the use of prochlorperazine  -  Apr 8, 2005
..."Thus, caution has to be paid on the use of prochlorperazine particularly for patients ... Keywords: Yamanashi, Japan, Prochlorperazine, Antipsychotic Drug, ... Pay-Per-View - Drug Week - Factiva, from Dow Jones

Throwing Sea Sickness Overboard  -  Oct 29, 2007
Meclizine, Dimenhydrinate, Prochlorperazine, and Promethazine can all treat the symptoms of sea sickness and should be taken prior to boarding. ... Ivanhoe Broadcast News

… Administrative Code - 77 Ill. Adm. Code 790.7580 PROCHLORPERAZINE …  -  Aug 10, 2005
77 Ill. Adm. Code 790.7580 PROCHLORPERAZINE MALEATE (Repealed) Repealed. (Source: Repealed at 17 Ill. Reg. 15916, effective September 20, 1993) ... Pay-Per-View - Illinois Administrative Code - Loislaw

… Administrative Code - 77 Ill. Adm. Code 790.7540 PROCHLORPERAZINE …  -  Aug 10, 2005
77 Ill. Adm. Code 790.7540 PROCHLORPERAZINE EDISYLATE (Repealed) Repealed. (Source: Repealed at 17 Ill. Reg. 15916, effective September 20, 1993) ... Pay-Per-View - Illinois Administrative Code - Loislaw

drug delivery system, buccal prochlorperazine, BioDelivery Sciences …  -  Feb 21, 2005
...second quarter 2005. BDSI (through its subsidiary Arius) licensed the product from Reckitt Benckiser. BDSI has entered into a licensing agreement with an ... Pay-Per-View - R & D Focus Drug News - Factiva, from Dow Jones

Phenothiazines (Systemic).  -  May 1, 2006
Prochlorperazine (proe-klor-PAIR-a-zeen)(***) 9.Promazine ( PROE-ma-zeen)(s.)(*) 10.Thioproperazine (thye-oh-proe-PAIR-a-zeen)(*) ... Free with registration - USP DI-Volume II, Advice for the... - AccessMyLibrary.com

Valeant receives FDA marketing approval for cannabinoid Cesamet.  -  May 16, 2006
Either prochlorperazine or placebo was used as the comparator. The prochlorperazine-controlled studies consisted of two flexible-dose, crossover studies ... Pay-Per-View - Company Reports - Factiva, from Dow Jones

Evidence-based Review of the Black-box Warning for Droperidol  -  Jul 3, 2007
Comparisons of the efficacy of ondansetron, droperidol, prochlorperazine, and metoclopramide have found that droperidol and prochlorperazine are comparable ... Medscape

Alexza Completes Enrollment in AZ-001 Phase IIb Clinical Trial in …  -  Dec 13, 2006
Prochlorperazine is currently approved in the United States for the treatment of ... In several published clinical studies, 10 mg of prochlorperazine ... Free with registration - PR Newswire - AccessMyLibrary.com

Press Release: Alexza Completes Enrollment in Second Phase 3 Clinical...  -  Oct 16, 2008
AZ-001 (Staccato prochlorperazine ... migraine headaches has completed Phase 2 testing. AZ-104 (Staccato loxapine) for ... ... Pay-Per-View - PR Newswire - HighBeam Research

Alexza Initiates AZ-001 Phase IIb Clinical Trial in Patients With...  -  Jun 6, 2006
Prochlorperazine is currently approved in the United States for the treatment of ... In several published clinical studies, 10 mg of prochlorperazine ... RedOrbit

Press Release: Alexza Pharmaceuticals to Present AZ-001 Phase IIb …  -  May 31, 2007
The Company has five product candidates in clinical development; AZ-001 (Staccato prochlorperazine) for the acute treatment of migraine headaches, ... Pay-Per-View - PR Newswire - HighBeam Research

Cancer Therapy; US FDA grants marketing approval to Valeant for …  -  Jun 14, 2006
Either prochlorperazine or placebo was used as the comparator. The prochlorperazine-controlled studies consisted of 2 flexible-dose, crossover studies (143 ... Pay-Per-View - Medical Letter on the CDC & FDA - Factiva, from Dow Jones

Cancer Therapy; US FDA grants marketing approval to Valeant for …  -  Jun 16, 2006
Either prochlorperazine or placebo was used as the comparator. The prochlorperazine-controlled studies consisted of 2 flexible-dose, crossover studies (143 ... Pay-Per-View - Science Letter - Factiva, from Dow Jones

Press Release: Merrill Lynch Global Pharmaceutical, Biotechnology & …  -  Jan 29, 2008
About Alexza Pharmaceuticals Alexza Pharmaceuticals is an emerging pharmaceutical ... clinical development; AZ-001 (Staccato prochlorperazine ... ... Pay-Per-View - PR Newswire - HighBeam Research

Stock Market Update, IPO profiles, Earnings Call Transcripts,...  -  Dec 22, 2005
The API of AZ-001 is prochlorperazine, a drug belonging to the class of drugs known as ... Prochlorperazine is currently approved in oral, injectable and ... 123Jump.com

Droperidol Better Antiemetic, but It Causes Akathisia  -  Jul 1, 2006
Bottom Line: Although droperidol is significantly better at reducing the severity of nausea than metoclopramide or prochlorperazine, it causes significantly ... AAFP News Now

PulseClinical: NEED TO KNOW - VERTIGO.  -  Jan 23, 2008
The standard treatment is prochlorperazine prescribed at 5-10mg three ... Buccal prochlorperazine is useful for patients with severe vertigo as it acts more ... Free with registration - Pulse - AccessMyLibrary.com

Cannabis.(Drug overview)  -  Feb 1, 2007
Herman TS, Einhorn LE, Jones SE et al: Superiority of nabilone over prochlorperazine as an antiemetic in patients receiving cancer chemotherapy. ... Free with registration - AltCareDex Alternative Medicines - AccessMyLibrary.com

Pennsylvania Code of Regulations - 28 Pa. Code § 25.58B. Generically ...  -  Jul 16, 2005
Labs Steris Labs PROCHLORPERAZINE EDISYLATE Injection Prochlorperazine Edisylate ... Kline & French PROCHLORPERAZINE MALEATE Tablets Compazine Smith, ... Pay-Per-View - Pennsylvania Code of Regulations - Loislaw

Press Release: Alexza to Present AZ-001 Phase IIa Clinical Data at...  -  Jun 12, 2006
The poster presentation, "Inhaled prochlorperazine in patients having an acute migraine attack" (Abstract F51) will be available for viewing at the meeting ... Pay-Per-View - PR Newswire - HighBeam Research

Merger and Acquisition Scenario  -  Feb 9, 2008
Target. AZ-001 (Inhaled Staccato Prochlorperazine); AZ-002 (Staccato Alprazolam); AZ-007 (Staccato Zaleplon); AZ-104 (Low-Dose Staccato Loxapine) ... $250.00 - Revere Reports - Revere

Merger and Acquisition Scenario  -  Oct 13, 2007
AZ-002 (Staccato Alprazolam); AZ-001 (Inhaled Staccato Prochlorperazine); AZ-104 (Low-Dose Staccato Loxapine); AZ-004 (Staccato Loxapine) ... $250.00 - Revere Reports - Revere

Press Release: Alexza Announces Positive Phase 1 Results With AZ-007 ...  -  Apr 29, 2008
About Alexza Pharmaceuticals Alexza Pharmaceuticals is an emerging pharmaceutical ... clinical development; AZ-001 (Staccato prochlorperazine ... ... Pay-Per-View - PR Newswire - HighBeam Research

Merger and Acquisition Scenario  -  May 12, 2007
Target. AZ-002 (Staccato Alprazolam); AZ-001 (Inhaled Staccato Prochlorperazine); AZ-004 (Staccato Loxapine); AZ-007 (Staccato Zaleplon) ... $250.00 - Revere Reports - Revere

New study shows Emezine® demonstrates more efficient absorption  -  Dec 12, 2005
Gary Cantrell, Executive Vice President of Sales and Marketing for Accentia's specialty pharmaceuticals division said, "Prochlorperazine is widely used for ... eurekalert.org

BioDelivery Sciences Announces Promising Results of Meeting with FDA ...  -  Jun 9, 2006
...regarding BDSI's new drug application (NDA) for the Emezine(R) (prochlorperazine maleate) buccal tablets for the treatment of nausea and vomiting. ... Free with registration - Business Wire - AccessMyLibrary.com

Alexza Pharmaceuticals to Present AZ-001 Phase IIb Clinical Data at...  -  May 31, 2007
The Company has five product candidates in clinical development; AZ-001 (Staccato prochlorperazine) for the acute treatment of migraine headaches, ... $4.95 - PR Newswire - ECNext

Cleanup of phenothiazine drugs from plasma using the novel polymeric ...  -  Sep 1, 2005
However, with 2% TFA in methanol/acetonitrile, the recovery yield of prochlorperazine increased to 87%. This behavior is attributable to strong multiple ... Free with registration - LC-GC North America - AccessMyLibrary.com

Why It Is Used  -  Dec 29, 2008
Promethazine and prochlorperazine are prescribed to control severe nausea and ... Promethazine and prochlorperazine can help stop nausea and vomiting caused ... WebMD

Merger and Acquisition Scenario  -  Aug 11, 2007
The Company's lead product candidates are AZ-001 (Staccato prochlorperazine), AZ-002 (Staccato alprazolam), AZ-004 (Staccato loxapine) and AZ-003 (Staccato ... $250.00 - Revere Reports - Revere

A case of metoclopramide-induced oculogyric crisis in a 16-year-old...  -  Nov 1, 2006
Schumock GT, Martinez E. Acute oculogyric crisis after administration of prochlorperazine. South Med J 1991;84:407-408. 3. Skorin L Jr, Onofrey BE, ... Free with registration - Southern Medical Journal - AccessMyLibrary.com

Merger and Acquisition Scenario  -  Dec 15, 2007
Target. AZ-002 (Staccato Alprazolam); AZ-001 (Inhaled Staccato Prochlorperazine); AZ-104 (Low-Dose Staccato Loxapine); AZ-004 (Staccato Loxapine) ... $250.00 - Revere Reports - Revere

Cannabis.  -  May 1, 2006
Herman TS, Einhorn LE, Jones SE et al:Superiority of nabilone over prochlorperazine as an antiemetic in patients receiving cancer chemotherapy. ... Free with registration - AltCareDex Alternative Medicines - AccessMyLibrary.com

Merger and Acquisition Scenario  -  Sep 15, 2007
Target. AZ-002 (Staccato Alprazolam); AZ-001 (Inhaled Staccato Prochlorperazine); AZ-104 (Low-Dose Staccato Loxapine); AZ-004 (Staccato Loxapine) ... $250.00 - Revere Reports - Revere

Alexza to Present AZ-001 Phase IIa Clinical Data at the American …  -  Jun 12, 2006
The poster presentation, "Inhaled prochlorperazine in patients having an acute migraine attack" (Abstract F51) will be available for viewing at the meeting ... RedOrbit

Alexza Reports Second Quarter Financial Results and Updates Its …  -  Aug 10, 2006
An abstract of these results, "Inhaled prochlorperazine reduces headache pain in patients having an acute migraine attack," was published in the May issue ... Free with registration - PR Newswire - AccessMyLibrary.com

Migraine Headaches - Medications  -  Jul 3, 2007
Antinausea drugs (such as prochlorperazine or metoclopramide) may also be prescribed alone to treat migraine symptoms. ... WebMD

Cannabis.  -  Aug 1, 2006
Herman TS, Einhorn LE, Jones SE et al:Superiority of nabilone over prochlorperazine as an antiemetic in patients receiving cancer chemotherapy. ... Free with registration - AltCareDex Alternative Medicines - AccessMyLibrary.com

Deputies: This growhouse was also a home  -  Apr 5, 2008
...in a bedroom weighing 19.5 grams, plus various quantities of pills identified as Darvocet, Serex, Neurontin, Carisoprodal and Prochlorperazine. ... WINKNEWS.com

Merger and Acquisition Scenario  -  Apr 1, 2006
Target. AZ-001 (Staccato Prochlorperazine); AZ-002 (Staccato Alprazolam); AZ-004 (Staccato Loxapine); AZ-003 (Staccato Fentanyl) ... $250.00 - Revere Reports - Revere

What are effective medical treatments for adults with acute migraine?(...  -  Jun 1, 2006
Prochlorperazine is more effective than metoclopramide in headache pain ... Valproate, ketorolac, IV magnesium, prochlorperazine, and metoclopramide are all ... $4.95 - Journal of Family Practice - ECNext

Press Release: Alexza Initiates AZ-001 Phase IIb Clinical Trial in...  -  Jun 6, 2006
PR Newswire; December 13, 2006 ; 700+ words ... ... prochlorperazine) in patients ... About AZ-001 (Staccato prochlorperazine ... the acute treatment of ... Pay-Per-View - PR Newswire - HighBeam Research

Q and A - Health In Focus - Health And Fitness - smh.com.au  -  Mar 23, 2006
The problem with using anti-emetics such as metoclopramide (Maxolon) and prochlorperazine (Stemetil) in anybody is the risk of side effects. ... Sydney Morning Herald

Management of common opioid-induced adverse effects.(dosage and …  -  Oct 15, 2006
...(14) Haloperidol (Haldol) and prochlorperazine (Compazine) are considered first-line options, primarily based on expert opinion. (3,10) Adverse effects such ... Free with registration - American Family Physician - AccessMyLibrary.com

Home administration of high-dose oral busulfan in patients undergoing...  -  Feb 26, 2007
Antiemetic therapy consisted of prochlorperazine 10 mg orally 30 min before each BU ... Patients were also given lorazepam and prochlorperazine for home ... Nature.com

The Prolactin Response to Neuroleptic Drugs. A Test of Dopaminergic …  -  Aug 1, 2005
Repeated administrations of haloperidol (1 mg im) and prochlorperazine (4 mg iv) demonstrated ... Dose-PRL response curves of haloperidol, prochlorperazine, ... Journal of Clinical Endocrinology and...

Management of common opioid-induced adverse effects.(dosage and …  -  Oct 15, 2006
...(14) Haloperidol (Haldol) and prochlorperazine (Compazine) are considered first-line options, primarily based on expert opinion. (3,10) Adverse effects such ... $4.95 - American Family Physician - ECNext

Press Release: Alexza Reports 2007 Year-End Financial Results and …  -  Mar 17, 2008
AZ-001 (Staccato prochlorperazine) is being developed for the acute treatment of migraine headaches. Alexza reported positive results from a 400 patient ... Pay-Per-View - PR Newswire - HighBeam Research

Drugs, pregnancy, and lactation: GI agents: part I.(Obstetrics)  -  Nov 15, 2005
Other common oral medications for NVP include prochlorperazine (Compazine), metoclopramide (Reglan), trimethobenzamide (Tigan), promethazine (Phenergan), ... Free with registration - OB GYN News - AccessMyLibrary.com

Press Release: Alexza Pharmaceuticals to Present AZ-004 Phase 2a …  -  May 1, 2008
Phase IIb clinical trial of AZ-001 (Staccato prochlorperazine ... headaches. More information on Alexza Pharmaceuticals Inc available in the members ... ... Pay-Per-View - PR Newswire - HighBeam Research

Merger and Acquisition Scenario  -  May 10, 2008
Target. AZ-002 (Staccato Alprazolam); AZ-007 (Staccato Zaleplon); AZ-104 (Low-Dose Staccato Loxapine); AZ-001 (Inhaled Staccato Prochlorperazine) ... $250.00 - Revere Reports - Revere

ANTIHISTAMINE (Oral route, Parenteral route, Rectal route).(Drug …  -  May 1, 2007
Prochlorperazine * Propafenone * Quetiapine * Quinidine * Quinine * Risperidone ... Prochlorperazine * Propafenone * Protriptyline * Quetiapine * Quinidine ... Free with registration - USP DI-Volume II, Advice for the... - AccessMyLibrary.com

Preventing postoperative nausea and vomiting.(Tips)  -  Oct 15, 2006
Layeeque and colleagues studied the ability of the combination of dronabinol (Marinol; an anticannabinoid) and prochlorperazine (Compazine; ... Free with registration - American Family Physician - AccessMyLibrary.com

Alexza Reports Second Quarter Financial Results and Updates …  -  Aug 13, 2007
The Company has six product candidates in development; AZ-001 (Staccato prochlorperazine) for the acute treatment of migraine headaches, AZ-004 (Staccato ... Free with registration - PR Newswire - AccessMyLibrary.com

Manage headaches while pregnant  -  Jan 5, 2007
Trimethobenzamide, chlorpromazine, prochlorperazine can be taken orally, as an injection, and suppository, and can all be used safely. ... iAfrica.com - iafrica.com

FLUOROQUINOLONE (Oral route, Injection route, Intravenous route).( …  -  May 1, 2007
Prochlorperazine * Promazine * Promethazine * Propiomazine * Protriptyline * Quinidine * Ranolazine * Recainam * Sotalol * Terfenadine * Thiethylperazine ... Free with registration - USP DI-Volume II, Advice for the... - AccessMyLibrary.com

Withdrawal Effects When Discontinuing Antipsychotic Medications  -  Apr 18, 2006
For instance, anticholinergics, beta-blockers, prochlorperazine (Compazine), or benzodiazepines have all been used for this purpose. [4] ... Medscape

Intramuscular droperidol for acute migraine: cause for concern?( …  -  Feb 1, 2005
In fact, droperidol has been directly compared with prochlorperazine for the acute treatment of migraine, with favorable results. (6) ... $4.95 - Consultant - ECNext

Merger and Acquisition Scenario  -  May 10, 2008
Target. AZ-002 (Staccato Alprazolam); AZ-007 (Staccato Zaleplon); AZ-104 (Low-Dose Staccato Loxapine); AZ-001 (Inhaled Staccato Prochlorperazine) ... $250.00 - Revere Reports - Revere

FINAL TRANSCRIPT  -  May 1, 2008
So the most advanced is Staccato prochlorperazine, our drug AZ-001. About a year ago, we. had very strong Phase IIa results and then Phase IIb results in a ... $54.00 - Thomson StreetEvents - Alacra Store

Factiva Search  -  Apr 5, 2005
2005 APR 5 - (NewsRx.com) -- The antipsychotic and antiemetic drug prochlorperazine delays the ventricular repolarization ... ... Pay-Per-View - Life Science Weekly - Factiva, from Dow Jones

Merger and Acquisition Scenario  -  May 10, 2008
Target. AZ-002 (Staccato Alprazolam); AZ-007 (Staccato Zaleplon); AZ-104 (Low-Dose Staccato Loxapine); AZ-001 (Inhaled Staccato Prochlorperazine) ... $250.00 - Revere Reports - Revere

Merger and Acquisition Scenario  -  Oct 21, 2006
Target. AZ-002 (Staccato Alprazolam); AZ-001 (Staccato Prochlorperazine); AZ-004 (Staccato Loxapine); AZ-003 (Staccato Fentanyl) ... $250.00 - Revere Reports - Revere

Merger and Acquisition Scenario  -  Jul 7, 2007
AZ-002 (Staccato Alprazolam); AZ-001 (Inhaled Staccato Prochlorperazine); AZ-104 (Low-Dose Staccato Loxapine); AZ-004 (Staccato Loxapine) ... $250.00 - Revere Reports - Revere

Article: Migraine headaches.(MEDICAL MAILBOX) - Saturday Evening …  -  Sep 1, 2005
PR Newswire; June 6, 2006 ; 700+ words ... ... prochlorperazine) in patients with migraine headaches. AZ-001 is an inhalation product ... developed for the ... Pay-Per-View - Saturday Evening Post - HighBeam Research

Merger and Acquisition Scenario  -  May 10, 2008
Target. AZ-002 (Staccato Alprazolam); AZ-007 (Staccato Zaleplon); AZ-104 (Low-Dose Staccato Loxapine); AZ-001 (Inhaled Staccato Prochlorperazine) ... $250.00 - Revere Reports - Revere

Drugs, pregnancy, and lactation: GI agents: part I.(Obstetrics) |...  -  Nov 15, 2005
Other common oral medications for NVP include prochlorperazine (Compazine), metoclopramide (Reglan), trimethobenzamide (Tigan), promethazine (Phenergan), ... Pay-Per-View - OB GYN News - HighBeam Research

BOY ACCUSED OF SELLING MEDICATIONS TO CLASSMATES  -  Jun 9, 2005
The following week, the boy sold 26 pills of prochlorperazine to another 14-year-old girl, police said. When police asked if he knew what the pills could do ... Pay-Per-View - Morning Call - ProQuest Archiver

GI agents: Part I.(Drugs, Pregnancy, And Lactation) | Article from...  -  Dec 1, 2005
Other common oral medications for NVP include prochlorperazine (Compazine), metoclopramide (Reglan), trimethobenzamide (Tigan), promethazine (Phenergan), ... Pay-Per-View - Family Practice News - HighBeam Research

GI agents: Part I.(Drugs, Pregnancy, And Lactation)  -  Dec 1, 2005
Other common oral medications for NVP include prochlorperazine (Compazine), metoclopramide (Reglan), trimethobenzamide (Tigan), promethazine (Phenergan), ... Pay-Per-View - Family Practice News - Factiva, from Dow Jones

Zofran, Xopenex HFA inhaler.(New & Approved) | Article from Family …  -  May 15, 2005
Hyperemesis gravidarum, requires intravenous antiemetics, such as droperidol (Inapsine), prochlorperazine, and ondansetron ... ... Pay-Per-View - Family Practice News - HighBeam Research

Merger and Acquisition Scenario  -  May 10, 2008
Target. AZ-002 (Staccato Alprazolam); AZ-007 (Staccato Zaleplon); AZ-104 (Low-Dose Staccato Loxapine); AZ-001 (Inhaled Staccato Prochlorperazine) ... $250.00 - Revere Reports - Revere

Merger and Acquisition Scenario  -  May 10, 2008
Target. AZ-002 (Staccato Alprazolam); AZ-007 (Staccato Zaleplon); AZ-104 (Low-Dose Staccato Loxapine); AZ-001 (Inhaled Staccato Prochlorperazine) ... $250.00 - Revere Reports - Revere

Merger and Acquisition Scenario  -  Feb 9, 2008
Target. AZ-001 (Inhaled Staccato Prochlorperazine); AZ-002 (Staccato Alprazolam); AZ-007 (Staccato Zaleplon); AZ-104 (Low-Dose Staccato Loxapine) ... $250.00 - Revere Reports - Revere

Merger and Acquisition Scenario  -  May 10, 2008
Target. AZ-002 (Staccato Alprazolam); AZ-007 (Staccato Zaleplon); AZ-104 (Low-Dose Staccato Loxapine); AZ-001 (Inhaled Staccato Prochlorperazine) ... $250.00 - Revere Reports - Revere

Merger and Acquisition Scenario  -  May 10, 2008
Target. AZ-002 (Staccato Alprazolam); AZ-007 (Staccato Zaleplon); AZ-104 (Low-Dose Staccato Loxapine); AZ-001 (Inhaled Staccato Prochlorperazine) ... $250.00 - Revere Reports - Revere

Merger and Acquisition Scenario  -  May 13, 2006
Target. AZ-001 (Staccato Prochlorperazine); AZ-002 (Staccato Alprazolam); AZ-004 (Staccato Loxapine); AZ-003 (Staccato Fentanyl) ... $250.00 - Revere Reports - Revere

Merger and Acquisition Scenario  -  Apr 29, 2006
AZ-001 (Staccato Prochlorperazine); AZ-002 (Staccato Alprazolam); AZ-004 (Staccato Loxapine); AZ-003 (Staccato Fentanyl) ... $250.00 - Revere Reports - Revere

Press Release: Alexza Selected to Join Russell 3000(R) Index. - PR …  -  Jun 22, 2007
The Company has six product candidates in development; AZ-001 (Staccato prochlorperazine) for the acute treatment of migraine headaches, AZ-004 (Staccato ... Pay-Per-View - PR Newswire - HighBeam Research

Press Release: Alexza Reports Second Quarter Financial Results and …  -  Aug 10, 2006
An abstract of these results, "Inhaled prochlorperazine reduces headache pain in patients having an acute migraine attack," was published in the May issue ... Pay-Per-View - PR Newswire - HighBeam Research

Merger and Acquisition Scenario  -  May 10, 2008
Target. AZ-002 (Staccato Alprazolam); AZ-007 (Staccato Zaleplon); AZ-104 (Low-Dose Staccato Loxapine); AZ-001 (Inhaled Staccato Prochlorperazine) ... $250.00 - Revere Reports - Revere

Press Release: Alexza's AZ-001 Phase IIb Trial Meets Primary Endpoint...  -  Mar 26, 2007
PR Newswire; December 13, 2006 ; 700+ words ... ... completed patient enrollment in its Phase IIb clinical trial of AZ-001 (Staccato(R) prochlorperazine ... Pay-Per-View - PR Newswire - HighBeam Research

Merger and Acquisition Scenario  -  May 10, 2008
Target. AZ-002 (Staccato Alprazolam); AZ-007 (Staccato Zaleplon); AZ-104 (Low-Dose Staccato Loxapine); AZ-001 (Inhaled Staccato Prochlorperazine) ... $250.00 - Revere Reports - Revere

Merger and Acquisition Scenario  -  May 10, 2008
Target. AZ-002 (Staccato Alprazolam); AZ-007 (Staccato Zaleplon); AZ-104 (Low-Dose Staccato Loxapine); AZ-001 (Inhaled Staccato Prochlorperazine) ... $250.00 - Revere Reports - Revere

Merger and Acquisition Scenario  -  Oct 21, 2006
Target. AZ-002 (Staccato Alprazolam); AZ-001 (Staccato Prochlorperazine); AZ-004 (Staccato Loxapine); AZ-003 (Staccato Fentanyl) ... $250.00 - Revere Reports - Revere

Factiva Search  -  Apr 9, 2005
Antipsychotic Drug; Caution must be paid with the use of prochlorperazine. 09 April, 2005 Obesity, Fitness & Wellness Week ... Pay-Per-View - Obesity, Fitness & Wellness Week - Factiva, from Dow Jones

Press Release: Alexza Pharmaceuticals to Present AZ-104 Phase 2a …  -  Jun 23, 2008
Phase IIb clinical trial of AZ-001 (Staccato prochlorperazine ... headaches. More information on Alexza Pharmaceuticals Inc available in the members ... ... Pay-Per-View - PR Newswire - HighBeam Research

Press Release: Alexza to Release Top-Line Results from AZ-001 Phase …  -  Mar 23, 2007
The purpose of the conference call is to provide top-line results from two clinical trials: a Phase IIb study with AZ-001 (Staccato(R) prochlorperazine), ... Pay-Per-View - PR Newswire - HighBeam Research

Merger and Acquisition Scenario  -  Mar 24, 2007
Target. AZ-002 (Staccato Alprazolam); AZ-001 (Inhaled Staccato Prochlorperazine); AZ-004 (Staccato Loxapine); AZ-003 (Staccato Fentanyl) ... $250.00 - Revere Reports - Revere

Brand Names/Synonyms:
Prochlorperazine is also known by the following brand names and/or synonyms6140 R.P.; 6140 RP; Bayer a 173; Buccastem; COMPAZINE; Capazine; Chlormeprazine; Chlorperazine; Combid; Compazine; Compro; Emelent; Emetiral; Eskatrol; Kronocin; Meterazin; Meterazin Maleate; Meterazine; Nipodal; Novamin; Pasotomin; Prochloroperazine; Prochlorpemazine; Prochlorperazin; Prochlorperazine; Prochlorperazine Edisylate; Prochlorperazine Maleate; Prochlorpromazine; Procloperazine; Proclorperazine; RP-6140; SKF 4657; Stemetil; Tementil; Temetid; Vertigon

Drug Category:
Prochlorperazine is categorized under the following by the FDA: Antipsychotics; Antiemetics; Phenothiazines; ATC:N05AB04

Dosage Forms:
Tablets, Spansule, capsules, Vials, Suppositories, Syrup

Absorption:
rapidly absorbed following oral administration

Interactions:
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Chemical IUPAC Name:
2-chloro-10-[3-(4-methylpiperazin-1-yl)propyl]-10H-phenothiazine





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