Protonix

This page contains recent news articles, when available, and an overview of Protonix but does not offer medical advice. You should contact your physician with regard to any health issues or concerns.


Overview:

Protonix
(when available)

Pharmacology and use:
Pantoprazole is a substituted benzimidazole indicated for the short-term treatment (up to 16 weeks) in the healing and symptomatic relief of erosive esophagitis. Pantoprazole is a proton pump inhibitor (PPI) that suppresses the final step in gastric acid production. Short-term (up to 16 weeks) treatment of erosive esophagitis.

Mechanism Of Action:
Pantoprazole is a proton pump inhibitor (PPI) that suppresses the final step in gastric acid production by forming a covalent bond to two sites of the (H+,K+ )- ATPase enzyme system at the secretory surface of the gastric parietal cell. This effect is dose- related and leads to inhibition of both basal and stimulated gastric acid secretion irrespective of the stimulus.

News Articles on Pantoprazole

Indian drug makers maintain pace of US marketing approvals  -  ‎Jan 3, 2010‎
Cellcept; GlaxoSmithKline's blockbuster epilepsy drug, Keppra, and Wyeth's heartburn drug, Protonix, had lost patent protection in the past two years. ... Business Standard

Medical marijuana attorney Rob Corry: "The future is here"  -  ‎Dec 18, 2009‎
...which also utilizes conventional pharmaceuticals, including Levothyroxin, Welbutrin, Nasacort, Protonix, Enbrel, Albutorol, Valium, Morphine Sulphate, ... Westword (blog)

Saving money on prescriptions  -  ‎Dec 27, 2009‎
Plavix (France), Prevacid (Japan), Protonix (Germany), Symbicort (France and Singapore), Vytorin (Singapore), and Wellbutrin XL (Canada). ... Tampa Tribune

Research shows effectiveness of nondrug approaches  -  ‎Dec 10, 2009‎
That's why vegetarians taking heartburn drugs such as Aciphex, Nexium, Prevacid, Prilosec, Protonix or the diabetes drug metformin may be at higher risk of ... Youngstown Vindicator

Pain Meds Can Cause Serious Side Effects  -  ‎Dec 18, 2009‎
...omeprazole (Prilosec), esomeprazole (Nexium) and pantoprazole (Protonix). Another less common therapy that may be used is misoprostol (Cytotec). ... Greenwood Today

Generic Name: Pantoprazole, Pantopan, Protium, Pantozol, Pantor, Pantoloc ...  -  ‎Nov 11, 2009‎
Protonix is used to treat and maintain healing of erosive acid reflux disease, also known as erosive GERD (breaks in the lining of the esophagus), ... Pattaya Daily News

Acid Blockers Cause Pneumonia in Critically Ill Patients  -  ‎Nov 9, 2009‎
Online PR News – 09-November-2009 – A new study* shows that Protonix®, a popular drug prescribed for acid reflux, greatly increases the risk of ... Online PR News (press release)

What You Don't Know May Cost You When It Comes To Prescriptions  -  ‎Nov 4, 2009‎
For instance, if you have gastric reflux, Prilosec, Nexium, AcipHex or Protonix might be prescribed. But only Prilosec and Protonix have generics. ... WPXI.com

Teva Reports Third Quarter 2009 Results  -  ‎Nov 2, 2009‎
Lotrel, Protonix and Eloxatin, the current economic conditions, competition from brand-name companies that are under increased pressure to counter ... Reuters

Sun Pharmaceuticals reported Net Sales of Rs1,185.2cr for 2Q FY2010  -  ‎Oct 30, 2009‎
Sun's US subsidiary, Caraco, reported Net Sales of US$78.4mn which were up by 63.3% sequentially, driven by Protonix sales. Caraco received a one-time ... Stock Markets Review

Zacks Analyst Blog Highlights: Baker Hughes Inc., BJ Services, Teva ...  -  ‎Nov 5, 2009‎
...strong sales from existing products like generic versions of Adderall XR, Yasmin and Protonix helped North America sales grow 34% to $2164 million. ... Reuters

Teva Files Amended Complaint Against Momenta/Sandoz to Include Infringement of ...  -  ‎Nov 9, 2009‎
Lotrel®, Protonix® and Eloxatin®, the current economic conditions, competition from brand-name companies that are under increased pressure to counter ... WELT ONLINE

Teva Reports Strong Quarter  -  ‎Nov 4, 2009‎
...strong sales from existing products like generic versions of Adderall XR, Yasmin and Protonix helped North America sales grow 34% to $2164 million. ... Zacks.com

Teva, In Turnabout, Sues to Protect Its Multiple Sclerosis Drug Copaxone  -  ‎Nov 6, 2009‎
Eloxatin (oxaliplatin) to such blockbuster drugs as Adderall XR (amphetamine salts) for narcolepsy and ADHD and Protonix (pantoprazole) for acid reflux. ... BNET

Teva Introduces Fexofenadine HCl and Pseudoephedrine HCl Extended-Release ...  -  ‎Nov 3, 2009‎
...including that relating to the generic versions of Neurontin, Lotrel and Protonix, the current economic conditions, competition from brand-name ... Reuters

GERD Drugs May Cause Unexpected Side Effects  -  ‎Nov 1, 2009‎
...dexlansoprazole (Kapidex), esomeprazole (Nexium), lansoprazole (Prevacid), omeprazole (Prilosec), pantoprazole (Protonix), and rabeprazole (Aciphex). ... eMaxHealth

Wyeth to cut costs as Teva ships generic Protonix  -  Dec 24, 2007
By Toni Clarke. BOSTON, Dec 24 (Reuters) - Wyeth (WYE.N: Quote, Profile, Research) said on Monday it expects to revise its business plan and initiate cost ... Reuters UK

Wyeth launches generic of Protonix heartburn drug  -  Jan 29, 2008
By Ransdell Pierson. NEW YORK (Reuters) - Wyeth (WYE.N) said on Tuesday it had launched a US generic form of its blockbuster Protonix heartburn drug, ... Reuters

Wyeth files to block Teva, Sun forms of Protonix  -  Jun 25, 2007
NEW YORK, June 25 (Reuters) - Wyeth (WYE.N) said on Monday it asked a New Jersey federal court to stop Teva Pharmaceutical Industries Ltd. (TEVA. ... Reuters

Teva says it has not relaunched generic Protonix  -  Feb 1, 2008
SAN FRANCISCO (Thomson Financial) - Teva Pharmaceutical Industries Ltd. said Friday it has not relaunched and does not plan to ship additional units of ... Forbes

Wyeth injunction on Protonix denied, Teva says  -  Sep 7, 2007
WASHINGTON (Reuters) - A US court has denied a motion by drugmakers Wyeth and Altana aimed at stopping Teva Pharmaceutical from selling a generic version of ... Reuters India

Wyeth gets US subpoenas tied to Protonix  -  Aug 5, 2008
NEW YORK, Aug 4 (Reuters) - US prosecutors have sent subpoenas to Wyeth WYE.N seeking information related to the drugmaker's promotion and pricing of its ... Reuters India

Wyeth seeks injunction against generic Protonix  -  Aug 1, 2007
LOS ANGELES (Reuters) - Wyeth and its partner Nycomed said on Tuesday that Teva Pharmaceuticals and Sun Pharmaceuticals have committed to not launching ... Reuters India

AstraZeneca says generic Protonix will hit Nexium  -  Jan 31, 2008
LONDON (Reuters) - The US launch of two generic forms of Wyeth's WYE.N ulcer drug Protonix will inevitably impact volume demand and increase pressure on ... Reuters UK

Wyeth Pharma and Teva extend standstill period in generic Protonix …  -  Jan 22, 2008
Since Teva received FDA approval for pantoprazole, a generic version of Wyeth's heartburn drug Protonix in Aug 2007, garnering 180 days of market ... Forbes

Teva says court gives it win in Protonix case  -  Sep 6, 2007
WASHINGTON, Sept 6 (Reuters) - Teva Pharmaceutical (TEVA.O) on Thursday said a US court denied a motion by drugmakers Wyeth and Altana aiming to stop Teva ... Reuters

Teva says gets FDA OK for generic Protonix  -  Aug 2, 2007
Aug 2 (Reuters) - Teva Pharmaceutical Industries Ltd. (TEVA.O) said the US health regulators have approved its generic version of Wyeth's heartburn drug ... Reuters

Teva generic Protonix has 68 pct of new prescriptions  -  Feb 12, 2008
TEL AVIV, Feb 12 (Reuters) - Teva Pharmaceutical Industries (TEVA.O) (TEVA.TA), the world's leading generic drugmaker, said on Tuesday its generic version ... Reuters

Teva Gets Protonix Nod  -  Apr 24, 2006
By TSC and IRIS Staff. Teva Pharmaceutical (TEVA - commentary - Cramer's Take) got tentative approval from the Food and Drug Administration to market its ... TheStreet.com - TheStreet.com (subscription)

Teva OK'd on generic of Wyeth's Protonix  -  Apr 21, 2006
JERUSALEM, April 21 (UPI) -- Teva said Friday it has been tentatively approved to market a generic version of Wyeth's Protonix for reflux disease. ... United Press International

Wyeth Profit Falls 4.6 Percent on Protonix Decline  -  Apr 22, 2008
By Lisa Rapaport. April 22 (Bloomberg) -- Wyeth earnings fell 4.6 percent, less than analysts anticipated, after generic competition slashed sales of its ... Bloomberg

Wyeth pricing questioned  -  Mar 15, 2005
The US attorney's subpoena requested quarterly Protonix price calculation ... Wyeth sold $2.3 billion of Protonix last year, according to IMS Health, ... Boston Globe

Sun to sell generic protonix in US  -  Sep 12, 2007
Mumbai, Sept. 11 Sun Pharmaceutical Industries Ltd is evaluating the launch options for its generic version of heart-burn medicine pantoprazole in the US ... Hindu Business Line

Wyeth Maps Out Cost-Cutting Plan  -  Oct 21, 2005
Among other big products, the severe heartburn drug Protonix reported sales of $405 million, up 7%. Sales of Prevnar, a vaccine to prevent pneumococcal ... TheStreet.com - TheStreet.com (subscription)

Prasco, ESI Lederle ink deal to distribute Protonix generic  -  Jan 30, 2008
A distribution agreement between Prasco Laboratories and a division of Wyeth Pharmaceuticals will allow the Cincinnati-based company to market a generic ... Bizjournals.com

Wyeth Beats Profit Targets  -  Apr 21, 2006
Protonix, for severe heartburn, reported $482 million in first-quarter sales, up 18% compared with the same period last year. Wyeth attributed the increase ... TheStreet.com - TheStreet.com (subscription)

Wyeth awaits Protonix court ruling after setbacks  -  Aug 17, 2007
By Lewis Krauskopf. NEW YORK, Aug 17 (Reuters) - Stung by a recent string of product setbacks, Wyeth WYE.N is now awaiting a US court ruling any day ... Reuters

Teva: Settlement over Protonix possible  -  Feb 4, 2008
Teva Pharmaceutical Industries Ltd., the world's biggest generic-drug maker, said over the weekend that there is still a chance of a settlement with Wyeth ... Jerusalem Post

Wyeth quarterly profit up 17%, yearly 10% - Still, the drugmaker...  -  Feb 1, 2008
And the year saw the likely loss of patent exclusivity on Protonix, whose 2007 sales of ... Wyeth this week launched its own generic version of Protonix, ... $2.95 - Philadelphia Inquirer - NewsBank

Santarus' stomach treatment out performs Protonix  -  Jun 15, 2005
Zegerid, a stomach acid treatment produced by pharmaceutical company Santarus, has been shown to significantly reduce gastric acidity throughout the night ... Pay-Per-View - Datamonitor News and Comment - Factiva, from Dow Jones

Teva launches generic Protonix, ups EPS forecast  -  Dec 24, 2007
TEL AVIV, Dec 24 (Reuters) - Israel's Teva Pharmaceutical Industries Ltd. (TEVA.O) (TEVA.TA) said on Monday it has commercially launched pantoprazole sodium ... Reuters

Wyeth 3Q profit falls but meets forecasts  -  Oct 22, 2008
Wyeth started cutting jobs earlier this year after its blockbuster heartburn drug Protonix lost patent protection and the market opened to cheaper generic ... FOXNews

Wyeth outlook cut to stable on launch of Protonix generic - Moody's  -  Feb 1, 2008
MUMBAI (Thomson Financial) - Moody's Investors Service cut the outlook on pharma company Wyeth's ratings to stable from positive, primarily citing the ... Forbes

Wyeth 3Q profit falls on charge  -  Oct 18, 2007
Sales of severe heartburn drug Protonix fell 6 percent. With two generic drug makers challenging its patent ahead of its expiration in three years, ... San Diego Union - Tribune - San Diego Union Tribune

Altana, Wyeth sue India's Sun Pharma  -  Apr 22, 2005
Altana said Protonix generated 2.5 billion euros ($3.26 billion) in worldwide ... Altana, based in Bad Homburg, Germany, said its sales of Protonix were 1.2 ... Financial Express

Drug maker Wyeth cutting 1,200 sales jobs  -  Mar 28, 2008
4 seller Protonix, a severe heartburn drug with 2007 sales of nearly $1.9 billion, would keep total revenue flat this year. ... USA Today

Metabolic disorder might be cause of body odor  -  Dec 9, 2006
A. Medications that suppress acid formation in the stomach (Aciphex, Nexium, Prevacid, Prilosec, Protonix) are quite good at relieving symptoms of reflux ... Youngstown Vindicator

Wyeth Receives FDA Approval of Protonix for Delayed-Release Oral …  -  Nov 15, 2007
COLLEGEVILLE, Pa., Nov. 15 /PRNewswire-FirstCall/ -- Wyeth Pharmaceuticals, a division of Wyeth , announced today that the US Food and Drug Administration ... Free with registration - PR Newswire - AccessMyLibrary.com

Protonix, Prevacid, Nexium linked to spread of deadly bacteria C....  -  Aug 9, 2006
A potentially deadly bacteria, C. difficile (Clostridium difficile), has been showing up outside of hospitals, and doctors at the Centers for Disease ... HealthCentral.com

Salix Pharmaceuticals Announces XIFAXAN Co-Promotion; ALTANA …  -  Mar 3, 2005
This ALTANA sales force currently promotes Protonix(R) (pantoprazole) for the ... Protonix is the most successful product of the ALTANA Pharma group with ... Free with registration - Business Wire - AccessMyLibrary.com

Wyeth, Nycomed sue Novartis' Sandoz over heartburn drug  -  May 21, 2008
VX) that sought US Food and Drug Administration approval for a generic version of the heartburn drug Protonix, court papers show. ... Reuters

Dr. Reddy's Gets Tentative US Approval for Generic Protonix  -  Dec 23, 2007
By Suresh Seshadri. Dec. 24 (Bloomberg) -- Dr. Reddy's Laboratories Ltd., India's biggest drugmaker, received tentative US approval to sell its version of ... Bloomberg

Q4 2004 WYETH Earnings Conference Call - Part 1.  -  Jan 31, 2005
Effexor, Protonix, Enbrel, Prevnar and Zosyn showed strong growth in markets ... Within Wyeth the rate of growth of Effexor and Protonix will moderate as ... Free with registration - America's Intelligence Wire - AccessMyLibrary.com

Wyeth profit crimped by generic competition, restructuring  -  Jul 23, 2008
Protonix, which recently lost patent protection, saw sales plunge 59% to $228 million. ... Protonix sales were seen as plunging 65% to $190 million. ... MarketWatch

Wyeth Profit Lifted by Effexor, Protonix | Article from AP Online | …  -  Apr 21, 2006
Wyeth Profit Lifted by Effexor, Protonix ... find AP Online articles. AP Online 04-21-2006 Dateline: MADISON, NJ The drugmaker Wyeth said Friday that its fi ... Pay-Per-View - AP Online - HighBeam Research

Cheap Protonix Without Prescription  -  Jun 4, 2007
...system functioning), toxicology and theoretical pharmacology. Pharmacology is not identical with pharmacy, though in common usage the two Cheap Protonix ... Sokwanele

Wyeth Says It May Cut 10% of Jobs  -  Jan 26, 2008
Protonix and Effexor generated a combined $5.5 billion in sales in 2006. Analysts have cut peak annual revenue estimates for the delayed drugs to less than ... New York Times

Article: Wyeth Gets Subpoena for Protonix Pricing - AP Online |...  -  Mar 14, 2005
Wyeth Gets Subpoena for Protonix Pricing ... find AP Online articles. AP Online 03-14-2005 Dateline: WASHINGTON Wyeth Pharmaceuticals said it was ser... Pay-Per-View - AP Online - HighBeam Research

Wyeth Edges Out Beat, Raises Guidance  -  Jul 23, 2008
Sales of proton pump inhibitor Protonix, however, took a 59% sales hit due to ... Wyeth, which launched its own generic version of Protonix tablets in the ... TheStreet.com - TheStreet.com (subscription)

Brand Names/Synonyms:
Protonix is also known by the following brand names and/or synonymsBY 1023; CHEMBANK1787; Pantoloc; Pantoprazol [Inn-Spanish]; Pantoprazole; Pantoprazole Na; Pantoprazole Sodium; Pantoprazole [Usan:Ban:Inn]; Pantoprazolum [Inn-Latin]; Pantoprozole; Protonix; Protonix I.V.; Protonix Iv

Drug Category:
Protonix is categorized under the following by the FDA: Anti-ulcer Agents; Proton-pump Inhibitors; ATC:A02BC02

Dosage Forms:
TABLET (ENTERIC-COATED)

Absorption:
Pantoprazole is well absorbed; it undergoes little first- pass metabolism resulting in an absolute bioavailability of approximately 77%.

Interactions:
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Chemical IUPAC Name:
5-(difluoromethoxy)-2-[(3,4-dimethoxypyridin-2-yl)methylsulfinyl]-3H-benzoimidazole





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