Protopic

This page contains recent news articles, when available, and an overview of Protopic but does not offer medical advice. You should contact your physician with regard to any health issues or concerns.


Overview:

Protopic
(when available)

Pharmacology and use:
Tacrolimus, a macrolide immunosuppressant produced by Streptomyces tsukubaensis, is an immunosuppressive agent indicated for the treatment of patients receiving kidney and/or liver transplants. Tacrolimus has been demonstrated to suppress humoral immunity and, to a greater extent, cell-mediated reactions such as allograft rejection, delayed type hypersensitivity, collagen- induced arthritis, experimental allergic encephalomyelitis, and graft versus host disease. It has similar immunosuppressive properties to cyclosporine, but is much more potent in equal volumes. Tacrolimus is indicated for the prophylaxis of organ rejection in patients receiving allogeneic liver or kidney transplants. Used in a topical preparation in the treatment of severe atopic dermatitis, also used after bone marrow transplants and for severe refractory uveitis.

Mechanism Of Action:
Tacrolimus inhibits T-lymphocyte activation by first binding to an intracellular protein, FKBP-12. A complex of Tacrolimus-FKBP-12, calcium, calmodulin, and calcineurin is then formed and the phosphatase activity of calcineurin is inhibited. This prevents the dephosphorylation and translocation of nuclear factor of activated T-cells (NF-AT), a nuclear component thought to initiate gene transcription for the formation of lymphokines. Tacrolimus also inhibits the transcription for genes which encode IL-3, IL-4, IL-5, GM-CSF, and TNF-, all of which are involved in the early stages of T-cell activation. Additionally, Tacrolimus has been shown to inhibit the release of pre-formed mediators from skin mast cells and basophils, and to downregulate the expression of FceRI on Langerhans cells.

News Articles on Tacrolimus

Hur länge ska jag använda krämen?  -  ‎Dec 14, 2009‎
Mot det har jag fått protopic som jag ska ta en gång per dag vid behov. Vad innebär det? Ska jag ta det så länge jag har klåda eller tills det "vita" ... Expressen

Diary of a homeophobe: part four  -  ‎Nov 12, 2009‎
I took out the Protopic (horrible cream; good last resort) and decided enough was enough. People - specifically you people - may say that I have not ... guardian.co.uk

Astellas Pharma set to launch Prograf in India, works on marketing strategy  -  ‎Nov 12, 2009‎
Tacrolimus, owned by Astellas Pharma Inc., is sold under the tradenames Prograf, Advagraf, and Protopic. Prograf (tacrolimus) is indicated for the ... pharmabiz.com

Nielsen Announces Finalists for the First-Ever CLIO Healthcare Awards  -  ‎Oct 21, 2009‎
...the Whole Story -- Company: GSW Worldwide -- Uroxatral - Uroxatral Patient Brochure -- Company: Medicus Life Brands -- Protopic - A (Slightly Confusing) ... Reuters

Stay home with mild symptoms  -  ‎Oct 31, 2009‎
Embrel, Remicade,, Humira, Orencia, CellCept Protopic, cancer chemotherapy, radiation therapy; under five years; pregnant, heart failure, liver failure, ... Brantford Expositor

ΛεÏ?κη: Με ποιες μοÏ?φές εμφανίζεται  -  ‎Nov 10, 2009‎
τοπικά ανοσοτÏ?οποποιητικά φάÏ?μακα με εκπÏ?οσώπους το τακÏ?όλιμους (Elidel) και πιμεκÏ?όλιμους (Protopic), φωτοχημειοθεÏ?απεία (PUVA). ... Ιατροnet

„Gegen Cellulite gibt es kein Mittel“  -  ‎Nov 11, 2009‎
Mit einer entzündungshemmenden Salbe, die Kortison enthält, oder auch mit einer kortison-freien Alternative, zum Beispiel Protopic-Salbe, sollten die Hände ... Kölner Stadt-Anzeiger

US FDA orders cancer risk label on Novartis' Elidel, Astellas' Protopi...  -  Jan 20, 2006
Elidel Cream (pimecrolimus) produced by Novartis AG and Protopic Ointment (tacrolimus) made by Japan's Astellas Pharma - to the strongest category. ... Forbes

Eczema Treatments Get New Cancer Warning  -  Mar 10, 2005
Research presented at the meeting also linked Elidel and Protopic to about 25 ... Elidel was approved in 2001 and Protopic in 2000 to treat adult eczema, ... FOXNews

FDA Panel Urges Warnings on 2 Eczema Drugs  -  Feb 16, 2005
Although the risks posed by Elidel and Protopic remain far from clear, ... Protopic was approved in 2000 and Elidel in 2001 to treat eczema, a chronic, ... Washington Post

Are Elidel And Protopic Safe To Use On My Child's Skin?  -  Feb 27, 2008
Question: Are Elidel and Protopic safe to use on my child's skin and why do they have a "Black Box" warning? Answer: Elidel and Protopic are two relatively ... ABC News

Cancer warning over eczema creams  -  Mar 11, 2005
The Food and Drug Administration said research had shown that Elidel and Protopic may pose a cancer risk when absorbed into the body. ... BBC News

Sucampo Pharmaceuticals, Inc. v. Astellas Pharma, Inc., 471 F.3d 544...  -  Dec 22, 2006
On February 14, 2005, the United States Food and Drug Administration ("FDA") issued two alerts regarding a link between cancer and the use of Protopic, ... $2.95 - U.S. Court of Appeals, Fourth Circuit - VersusLaw

FDA Considers Warnings for Eczema Creams  -  Feb 12, 2005
Protopic and Elidel were approved in 2000 and 2001, respectively, to treat eczema, ... Both Novartis and Fujisawa Healthcare Inc., which makes Protopic, ... Washington Post

Digital Chosunilbo (English Edition) : Daily News in English About...  -  Mar 16, 2005
Since going on sale in the US, it has been reported that Protopic caused cancer ... Korea imported Elidel worth W2.1 billion (US$2.1 million) and Protopic ... 조선�보 - 조선�보(�문�)

… Agency Recommends Cautious Use Of Protopic/Protopy And Elidel  -  Mar 28, 2006
Finalising its safety review of Protopic/Protopy (tacrolimus) and Elidel ... Patients who are using Protopic/Protopy or Elidel should not stop or modify ... Medical News Today - Medical News Today (press release)

Skin Conditions: Atopic Dermatitis (Eczema)  -  Mar 1, 2007
The drugs, Elidel and Protopic, are skin creams that work by altering the immune system response to prevent flare-ups. On March 10, 2005, the FDA warned ... WebMD

Topical calcineurin inhibitors for atopic dermatitis  -  May 5, 2008
The US Food and Drug Administration (FDA) recommends caution when prescribing or using Elidel (pimecrolimus) cream and Protopic (tacrolimus) ointment ... WebMD

Astellas Pharma sued in St. Clair County by Protopic users  -  Oct 15, 2007
The manufacturer of a skin disease ointment is being sued in St. Clair County Circuit Court by plaintiffs who claim that use of Protopic caused cancer. ... St. Clair Record

FDA Approves Updated Labeling for Elidel and Protopic  -  Jan 22, 2006
Washington, DC - infoZine - The Food and Drug Administration (FDA) announced the approval of updated labeling for two topical eczema drugs, Elidel Cream ... Kansas City infoZine

Protopic suit refiled in St. Clair County  -  Feb 25, 2008
Astellas Pharma Inc. is being sued in St. Clair County Circuit Court again by claimants who allege Protopic, a skin disease ointment, caused lymphoma. ... Madison County Record

Protopic and Elidel for eczema: FDA takes inadequate action on cancer...  -  May 1, 2006
Early this year, the Food and Drug Administration issued a warning about two prescription topical creams for the common skin disease, eczema. ... $4.95 - HealthFacts - ECNext

FDA Orders 'Black Box' Warning for Eczema Drugs, Elidel and Protopic  -  Jan 26, 2006
In an important notification, the Federal Drug Administration (FDA) has announced the approval of updated labeling for two topical eczema drugs, Protopic ... Newsinferno.com

… Public Health Advisory About Elidel (Pimecrolimus) Cream and Protop...  -  Apr 19, 2005
Use Elidel and Protopic only as second-line agents for short-term and ... Avoid use of Elidel and Protopic in children younger than 2 years of age. ... DG News

Questionable risk  -  Mar 20, 2005
Since their introduction several years ago, Protopic and Elidel have provided relief ... Health-care providers should prescribe Elidel and Protopic only as ... OCRegister

Duplo launches GMP-Protopic digital laminator  -  Nov 29, 2006
Duplo International has officially launched the GMP-Protopic 520 Digital Laminator, following its technology debut at Digital print World in London last ... Graphic Repro

Making a case for 'marked' meds: Elidel, Protopic still important...  -  Apr 1, 2007
Some dermatologists continue to prescribe both Elidel and Protopic, despite a federally mandated "black box" warning on the labels. ... $4.95 - Dermatology Times - ECNext

TradeName : Pangraf, Vingraf, Prograf, Protopic, Tacromus  -  Dec 31, 2008
Why it is prescribed (Indications) : Tacrolimus is used to prevent rejection of Kidney, Heart and Liver Transplanted organ . It is also used for treatment ... MedIndia

… box warning to be added to Elidel and Protopic: FDA cautions...  -  Apr 1, 2005
ROCKVILLE, MD. -- The Food and Drug Administration is adding a black box warning to the health professional labels of pimecrolimus and tacrolimus and is ... Pay-Per-View - Skin & Allergy News - Factiva, from Dow Jones

… For Legal Action Against The Manufacturers Of Protopic Or Elidel...  -  Dec 4, 2006
LOS ANGELES/EWORLDWIRE/Dec. 4, 2006 --- "If you have been diagnosed with some form of lymphoma (including Non-Hodgkin's and Hodgkin's Disease), ... eworldwire.com

… health advisory issued for Elidel[R] and Protopic[R].(DRUG UPDATE)...  -  Jun 1, 2005
Public health advisory issued for Elidel[R] and Protopic[R].(DRUG UPDATE) ... find Dermatology Nursing articles. According to FDA MedWatch and the US Food ... Pay-Per-View - Dermatology Nursing - HighBeam Research

FDA Panel Urges Warnings on 2 Eczema Drugs | Article from The …  -  Feb 16, 2005
Although the risks posed by Elidel and Protopic remain far from clear, ... Protopic was approved in 2000 and Elidel in 2001 to treat eczema, a chronic, ... Pay-Per-View - Washington Post - HighBeam Research

Protopic effective for nickel-induced allergy  -  Jul 28, 2006
NEW YORK (Reuters Health) - Protopic, also known as tacrolimus 0.1 percent ointment, suppresses the signs and symptoms of skin allergy resulting in contact ... RedOrbit

FDA warns about Elidel, Protopic.(MEDICATION)(Food and Drug …  -  May 1, 2005
Two months ago, the US Food and Drug Administration asked it's Pediatric Advisory Committee to review two medications that are used to treat children with ... $4.95 - Child Health Alert - ECNext

Novartiss Elidel and Astellas's Protopic Were the Leading Branded …  -  Jul 10, 2006
Atopic dermatitis is one of the largest segments of the dermatology disease market in terms of patient population. However, sales in this market are ... Free with registration - M2 Presswire - AccessMyLibrary.com

FDA Warns About Cancer Risks of Elidel, Protopic for Eczema  -  Mar 18, 2005
The FDA has issued a public health warning about the potential cancer risks of two eczema drugs -- Novartis Pharmaceutical's Elidel and Fujisawa ... Pay-Per-View - FDAnews Drug Daily Bulletin - Factiva, from Dow Jones

Naperville woman says skin ointment caused breast cancer  -  Feb 22, 2007
Protopic and Elidel have been on the market for the last five years and, combined, ... A 2005 FDA report involving animals given high doses of protopic ... $2.95 - Naperville Sun - NewsBank

… health advisory issued for Elidel[R] and Protopic[R].(DRUG UPDATE)  -  Jun 1, 2005
According to FDA MedWatch and the US Food and Drug Administration (FDA) Web site (www.fda.org), on March 10, 2005 the FDA issued a public health advisory to ... $4.95 - Dermatology Nursing - ECNext

'I would have never put this on my body'  -  Mar 2, 2007
Protopic and Elidel have been on the market for the last five years and, combined, ... A 2005 FDA report involving animals given high doses of Protopic ... $2.95 - Naperville Sun - NewsBank

… black box for Elidel and Protopic.(Dermatologic Therapy) | Article...  -  Feb 1, 2006
FDA approves black box for Elidel and Protopic.(Dermatologic Therapy) ... find Skin & Allergy News articles. The US Food and Drug Administration last month ... Pay-Per-View - Skin & Allergy News - HighBeam Research

Eczema; FDA published advisory regarding Protopic and Elidel  -  Apr 12, 2005
2005 APR 12 - (NewsRx.com) -- The US Food and Drug Administration (FDA) has published a Public Health Advisory concerning the skin creams Protopic and ... Pay-Per-View - Life Science Weekly - Factiva, from Dow Jones

Search irishhealth.com  -  Jun 10, 2007
Do get protopic cream if bad. Avoid coffee like the plague. Sugar and diary products. ... He is advising that she starts on Protopic as she is severe. ... Irish Health

Duplo plans major debuts at Digital Print World  -  Sep 15, 2006
For the first time in the UK, the new GMP-Protopic 520 Digital Laminator ... The GMP-Protopic 520 runs at a maximum speed of 15m per minute and uses GMP's ... Graphic Repro

Eczema drugs tacrolimus (Protopic) and pimecrolimus (Elidel): cancer ...  -  Apr 26, 2005
Reason for posting: Many patients with eczema, or atopic dermatitis, are prescribed the topical immunomodulators tacrolimus and pimecrolimus. ... Free with registration - CMAJ: Canadian Medical Association... - AccessMyLibrary.com

Eczema; FDA published advisory regarding Protopic and Elidel  -  Apr 16, 2005
2005 APR 16 - (NewsRx.com) -- The US Food and Drug Administration (FDA) has published a Public Health Advisory concerning the skin creams Protopic and ... Pay-Per-View - Obesity, Fitness & Wellness Week - Factiva, from Dow Jones

… and Drug Administration; FDA published advisory regarding Protopic...  -  Apr 13, 2005
2005 APR 13 - (NewsRx.com) -- The US Food and Drug Administration (FDA) has published a Public Health Advisory concerning the skin creams Protopic and ... Pay-Per-View - Biotech Week - Factiva, from Dow Jones

… -center study of short and long-term use of Protopic Ointment in...  -  Sep 1, 2005
Inc. The purpose of the study is to determine the impact of topical corticosteroids on the safety and effectiveness of Protopic Ointment in the ... Free with registration - Journal of Drugs in Dermatology - AccessMyLibrary.com

Astellas puts warning on Protopic labels  -  Jan 21, 2006
DEERFIELD - Astellas Pharma US Inc. recently announced it has added new information to the labels on its topical calcineurin inhibitors, which includes ... $4.95 - Daily Herald - ECNext

Elidel (pimecrolimus) and Protopic (tacrolimus) may have a potential ...  -  May 1, 2005
Elidel (pimecrolimus) and Protopic (tacrolimus) may have a potential cancer risk, and the FDA advises that the products be used only as second-line agents ... Free with registration - Patient Care for the Nurse Practitioner - AccessMyLibrary.com

… made GSW Worldwide agency of record for eczema treatment Protopic.(...  -  Mar 1, 2005
Fujisawa Healthcare made GSW Worldwide agency of record for eczema treatment Protopic. Free with registration - Pharmaceutical Executive - AccessMyLibrary.com

… box warning to be added to Elidel and Protopic: FDA cautions...  -  Apr 1, 2005
Black box warning to be added to Elidel and Protopic: FDA cautions against off-label prescribing.(Dermatologic Therapy) ... find Skin & Allergy News ... Pay-Per-View - Skin & Allergy News - HighBeam Research

Black box warnings have hampered eczema therapy  -  Dec 25, 2008
Lawsuits were filed last year against the makers of Elidel and Protopic claiming ... “The black-box warnings placed on Elidel and Protopic are based on this ... HemOncToday

Update on Immunomodulating Topical Agents and NSAIDS  -  Aug 26, 2005
Protopic and Elidel are calcineurin inhibitors and immunosuppressants. Although their exact mechanism of action is not known, they exert direct ... RedOrbit

Sucampo suspends eye-drop tests, cites FDA concern  -  Jun 29, 2005
Sucampo is developing a drop for dry eye using tacrolimus, a drug to suppress the immune system which is also the active ingredient in Protopic. ... Washington Business Journal

… : Black box recommended for Elidel and protopic.(Skin Disorders) -...  -  Mar 15, 2005
Black box recommended for Elidel and protopic.(Skin Disorders) ... find Family Practice News articles. ROCKVILLE, MD. -- The Food and Drug Administration's ... Pay-Per-View - Family Practice News - HighBeam Research

Personal Lubricant Eases Dry Nostrils  -  Apr 25, 2005
The manufacturers of Elidel and Protopic claim the warnings are unjustified. Because the FDA says it could be years before the actual risk is clarified, ... HealthCentral.com

Drug Update  -  Jun 29, 2005
Elidel cream and Protopic ointment are topical immunosuppressant calcineurin ... Use Elidel and Protopic only as second-line agents for short- term and ... RedOrbit

… : FDA adds black box warning for Elidel, Protopic: the manufacturers...  -  Apr 1, 2005
FDA adds black box warning for Elidel, Protopic: the manufacturers have agreed to conduct research to determine if there is a risk of cancer in humans. Pay-Per-View - Internal Medicine News - HighBeam Research

… boxes added to labels for Elidel and Protopic: increased use,...  -  Apr 1, 2005
Black boxes added to labels for Elidel and Protopic: increased use, greater cancer risk is cited.(News) ... find Pediatric News articles. ROCKVILLE, MD. Pay-Per-View - Pediatric News - HighBeam Research

Elidel og Protopic: Bekymring for mulig kreftrisiko  -  Oct 20, 2007
Protopic og Elidel er immundempende legemidler i gruppen kalcineurinhemmere. Midler som virker dempende på immunsystemet øker risikoen for kreft og ... Statens legemiddelverk

Update on immunomodulating topical agents and NSAIDS.( …  -  Aug 1, 2005
Protopic and Elidel are calcineurin inhibitors and immunosuppressants. Although their exact mechanism of action is not known, they exert direct ... $4.95 - Dermatology Nursing - ECNext

SpørsmÃ¥l ang Pergotime og Protopic  -  Nov 14, 2008
1. I forbindelse med vanlig gyn undersøkelse hos Gynekolog nylig, nevnte jeg for henne at jeg i nærmere ett år har forsøkt å bli gravid uten resultat. ... Lommelegen.no

… and Informs Physicians and Patients on Changes to Protopic Label...  -  Jan 19, 2006
Astellas Pharma, whose local ... production of Protopic to Toyama, Japan . ... Protopic sales fall 32.7% Astellas' eczema treatment Protopic (tacrolimus) ... Pay-Per-View - PR Newswire - HighBeam Research

… – nye presiseringer om riktig bruk av Elidel (pimecrolimus) og...  -  Oct 20, 2007
Europeiske legemiddelmyndigheter anbefaler at Elidel og Protopic bare brukes ... Elidel og Protopic blir kontinuerlig overvåket med hensyn til sikkerhet og ... Statens legemiddelverk

DOCTORS QUESTION FDA'S BLACK-BOX WARNING ON CREAMS  -  Apr 24, 2005
Elidel and Protopic are both nonsteroidal creams used to treat eczema, ... And he said he would use Elidel and Protopic on children only age 2 or older. ... $2.95 - Charlotte Observer - NewsBank

Loislaw Federal District Court Opinions - LANCASTER v. ASTELLAS …  -  Sep 23, 2008
This case arises from injuries that Plaintiffs allege were caused by their use of Defendants' product, Protopic. Plaintiffs allege that Protopic causes ... Pay-Per-View - Loislaw Federal District Court Opinions - Loislaw

FINDINGS  -  Mar 11, 2005
Elidel and Protopic should be used only for short periods and only after other treatments ... Since the FDA approved Protopic in 2000 and Elidel in 2001, ... Pay-Per-View - Washington Post - ProQuest Archiver

Is FDA Playing Politics with Drug Warnings?  -  Mar 24, 2005
Help came from two skin creams for eczema, Protopic and Elidel, ... Tim Warner, a spokesman for Fujisawa, the manufacturer of Protopic, said that the ... ABC News

Loislaw Federal District Court Opinions - WEISS v. ASTELLAS PHARMA …  -  May 10, 2006
BACKGROUND Plaintiffs Philip and Cassandra Weiss filed this action alleging that the prescription drugs Protopic and Elidel, which are manufactured and sold ... Pay-Per-View - Loislaw Federal District Court Opinions - Loislaw

Best Fast Printing uses Renz Masterbind's celloglazing machine  -  Aug 10, 2007
Wong saw the benefit and opportunities that the Protopic Plus 520 ... Best Fast Printing has limited floor space and the Protopic fits in correctly. ... Ferret

Eczema: Discover the cream that can provide much-needed relief from …  -  Apr 4, 2005
Protopic is a topical treatment for eczema that may cause stinging, ... In the US, product packaging for Protopic and Elidel will be required to carry a ... Healthier Life - The Healthier Life

FDA advises using 2 atopic dermatitis drugs only as labeled  -  May 5, 2005
Both Elidel and Protopic are approved agents for the second line treatment of AD in ... Elidel and Protopic are 150% to 800% more expensive than comparable ... AAP News - AAP News (subscription)

两ç§?å?¯èƒ½è‡´ç™Œè?¯è†?对中国患者“影å“?范围ä¸?大â€?  -  Jan 20, 2006
FDA的公告说,由安斯泰æ?¥åˆ¶è?¯å…¬å?¸ç”Ÿäº§çš„“普特彼(PROTOPIC)â€?和由诺å?Žåˆ¶è?¯å…¬å?¸ç”Ÿäº§ 的“ELIDELâ€?这两ç§?è?¯ç‰©ï¼Œè™½ç„¶ç›®å‰?尚无直接è¯?æ?®è¡¨æ˜Žå…¶è‡´ç™Œæ€§ï¼Œä½†æ ¹æ?®å¤šå??患者ä¸?良å??应 ... 中新网

New Medication For Eczema Patients In Malaysia  -  Sep 28, 2005
..."Protopic is effective and well tolerated for long-term management of eczema in ... Protopic is an ointment-based topical immunomodulator first launched in ... Bernama - Bernama

Riesgo de cáncer con cremas antieczema Elidel y Protopic  -  Feb 17, 2005
Un grupo de expertos independientes de la agencia federal que regula la comercialización de medicamentos (FDA) estadounidense recomendó que las cremas de ... El Universo

Early data confirm the safety of tacrolimus.(News)(Clinical report) |...  -  Mar 1, 2007
Article: Black boxes added to labels for Elidel and Protopic: increased . ... Tacrolimus ointment (Protopic) is made ... in children aged 2 years and older. ... Pay-Per-View - Pediatric News - HighBeam Research

两ç§?湿疹è?¯å?¯èƒ½è‡´ç™ŒFDA责令须加"黑框警示"  -  Mar 27, 2006
...的医立妥(Elidel)和日本安斯泰�公�(AstellasPharma)生产的普特彼(Protopic)。 它们都是通过抑制人体�疫系统,�缓解湿疹症状。由于这两��物��类固醇,因此问世时 ... 新�网河�频�

Nuevas alertas en dos cremas para el eccema  -  Mar 12, 2005
La FDA (agencia del medicamento estadounidense) ha decidido que dos cremas recetadas para tratar la dermatitis atópica -Elidel (pimecrolimus) y Protopic ... elmundo.es

美國指Elidel å?ŠProtopic 濕疹藥è†?å?¯èƒ½è‡´ç™Œ  -  Jan 20, 2006
...美國食å“?å?Šè—¥ç‰©ç®¡ç?†å±€ï¼Œ è¦?求兩種å??為Elidel å?ŠProtopic 的濕疹藥è†?, 必須在包è£?加 上使用後å?¯èƒ½è‡´ç™Œå?Šåœ¨é†«ç™‚人員指導下使用的字å?¥ã€‚ 管ç?†å±€è¡¨ç¤ºï¼Œ 公眾應該在嘗試其他 ... 香港電å?° - 香港電å?°

Protopic – Emplois, Effets secondaires, Interactions - Médicaments - ...  -  Apr 27, 2005
Prenez votre santé en main avec notre bulletin d'information. Demeurez informé et en bonne santé! Nous recherchons des gens souffrant de pression artérielle ... Canoë

Cremes perigosos:autoridade recomenda alternativas  -  Mar 11, 2005
Trata-se do Elidel (pimecrolimus) e do Protopic (tacrolimus), dois medicamentos imunossupressores de aplicação tópica e indicados no tratamento de dermatite ... Diário IOL

美è?¯ç®¡å±€å»ºè®®æ…Žç”¨ä¸¤ç§?皮肤病è?¯è†?  -  Mar 15, 2005
...美国食�和�物管�局(FDA)日�建议慎用处方��美莫�(Elidel)和他克莫�(Protopic) 治疗湿疹,以���能产生的严��患。 �美国食�和�物管�局网站报�,研究显示 ... 中金在线

两ç§?è?¯è†?å?¯èƒ½è‡´ç™Œå…¶ä¸­ä¸€ç§?已在中国销售  -  Jan 23, 2006
FDA的公告说,由安斯泰æ?¥åˆ¶è?¯å…¬å?¸ç”Ÿäº§çš„“普特彼(PROTOPIC)â€?和由诺å?Žåˆ¶è?¯å…¬å?¸ç”Ÿäº§ 的“ELIDELâ€?这两ç§?è?¯ç‰©ï¼Œè™½ç„¶ç›®å‰?尚无直接è¯?æ?®è¡¨æ˜Žå…¶è‡´ç™Œæ€§ï¼Œä½†æ ¹æ?®å¤šå??患者ä¸?良å??应 ... 新浪网

FDA Considers Warnings for Eczema Creams | Article from The …  -  Feb 12, 2005
Protopic and Elidel were approved in 2000 and 2001, respectively, to treat eczema, ... Both Novartis and Fujisawa Healthcare Inc., which makes Protopic, ... Pay-Per-View - Washington Post - HighBeam Research

eczema For kids, milder medi ...  -  Oct 11, 2005
The study was funded by Astellas Pharma US Inc., which makes Protopic and which employed two of the eight primary authors; two others had received ... Pay-Per-View - Washington Post - ProQuest Archiver

'Black box' impacts TIM use: maligned meds still important; alternativ...  -  Mar 1, 2007
..."I had been using Elidel and Protopic for treating rosacea, psoriasis and ... However, she says her Elidel and Protopic prescriptions have decreased, ... $4.95 - Dermatology Times - ECNext

Vorsicht mit Elidel, Douglan und Protopic  -  Mar 23, 2006
Elidel, Douglan und Protopic sind nicht so unbedenklich, wie zuweilen verkündet: Ein Jahr nach der Medizin-Behörde in den USA hat nun auch das europäische ... Psoriasis-Netz

Nouvelles recommandations concernant l'utilisation de Protopic® et …  -  Mar 27, 2006
Une réévaluation européenne des données de sécurité d'Elidel® et Protopic® a été engagée en avril 2005 à la suite de la notification de cas de cancers ... InformationHospitaliere.com

MuszÄ… wypadać. Gdyby nie wypadaÅ‚y, nie zmieÅ›ciÅ‚yby siÄ™ na gÅ‚owie, bo ...  -  Feb 11, 2006
Ostatnio pojawiły się bardzo dobre leki do stosowania przy atopowym zapaleniu skóry - Elidel, Protopic - pozwalające osiągnąć rezultaty analogiczne do leków ... Subscription - Gazeta Wyborcza - AGORA S.A

ELIDEL ir PROTOPIC – nenustatyta ryÅ¡io tarp Å¡ių preparatų vartojimo...  -  Mar 27, 2006
JAV vaistų ir maisto administracija (FDA) 2006 m. sausio 15 d. įvykusiame pasitarime įvertino turimų vietinių kalcineurino inhibitorių saugumo duomenis ir ... medicine.lt

Seborroisk eksem  -  Nov 14, 2005
...(Elidel og Protopic kan ikke brukes samtidig med lysbehandling så man må velge en av delene, Elidel og Protopic virker dempende på betennelse i huden og tar ... Lommelegen.no

FDA Panel Urges Black Box Warnings for Two Eczema Treatments  -  Feb 20, 2005
Both Protopic and Elidel received approval as second-line treatments for patients who ... Notwithstanding, when both drugs were approved (Protopic in 2000; ... MedPage Today

Safety concern over skin drug  -  Jun 2, 2006
Speaking to irishhealth.com, a spokesperson for the IMB said that it 'is aware of the issues relating to Protopic', adding that these are currently being ... Irish Health

Search irishhealth.com  -  Jan 10, 2008
I really reccommend anyone try this, its the longest I've gone without using Elocon or protopic, which I didn't like, but had no other choice. ... Irish Health

Kortisonkrem eller ikke - hva er best?  -  Apr 1, 2005
Brukt på riktig måte er både lokale kortisonmidler, Elidel og Protopic svært effektive ... I en studie der en sammenlignet effekten av kortison og Protopic, ... Lommelegen.no

News about health and medicine  -  Mar 27, 2005
Two eczema creams, Elidel and Protopic, will receive new label warnings pointing out ... Elidel and Protopic are applied to the skin to control eczema by ... Seattle Times

Ongoing study suggests tacrolimus is safe for kids.(Skin Disorders) |...  -  Mar 1, 2007
Article: Black box recommended for Elidel and protopic.(Skin Disorders) ... Tacrolimus ointment (Protopic) is made ... in children aged 2 years and older. ... Pay-Per-View - Family Practice News - HighBeam Research

FINDINGS | Article from The Washington Post | HighBeam Research  -  Mar 11, 2005
Elidel and Protopic should be used only for short periods and only after other treatments ... Since the FDA approved Protopic in 2000 and Elidel in 2001, ... Pay-Per-View - Washington Post - HighBeam Research

eczema For kids, milder medi ... | Article from The Washington Post |...  -  Oct 11, 2005
The study was funded by Astellas Pharma US Inc., which makes Protopic and which employed two of the eight primary authors; two others had received ... Pay-Per-View - Washington Post - HighBeam Research

Atopic Dermatitis; EWGAD issues clinical guidance on use of topical …  -  Jan 29, 2005
Protopic has the most extensive clinical development programme ever conducted in dermatology. It shows efficacy over the entire spectrum of AD disease ... Pay-Per-View - Obesity, Fitness & Wellness Week - Factiva, from Dow Jones

Corrections.(Opinion)(Correction Notice) | Article from Pediatric...  -  May 1, 2005
In "Black Boxes Added to Labels for Elidel and Protopic" (April 2005, p. 1), the headline was overstated. It should have read, "Black Boxes to Be Added to ... Pay-Per-View - Pediatric News - HighBeam Research

Atopic Dermatitis; EWGAD issues clinical guidance on use of topical …  -  Jan 26, 2005
Protopic has the most extensive clinical development programme ever conducted in dermatology. It shows efficacy over the entire spectrum of AD disease ... Pay-Per-View - Immunotherapy Weekly - Factiva, from Dow Jones

Pimecrolimus (Elidel) krem  -  Jul 28, 2005
Protopic (tacrolimus salve) tilhører samme legemiddelgruppe som Elidel og er ... Indirekte sammenligninger kan tyde på at Protopic er mer effektiv enn ... Statens legemiddelverk

Astellas Pharma phase-out under way  -  Apr 12, 2006
The plant at 3125 Staley Road, which has 105 employees, makes Protopic ... Consolidating the worldwide production of Protopic in Japan is part of that ... Bizjournals.com

Best overall advertising campaign in professional press.  -  Nov 1, 2008
Protopic Ointment--Itchcraft Campaign [ILLUSTRATION OMITTED] By focusing on efficacy. GSW effectively revitalized eczema treatment Protopic. ... $9.94 - Medical Marketing & Media - Alacra Store

EMEA: cautela su impiego tacrolimus e pimecrolimus topici  -  Mar 29, 2006
Nel frattempo, il CHMP ha raccomadato che Protopic/Protopy ed Elidel siano usati con ... I pazienti che stanno usando Protopic/Protopy ed Elide non devono ... Pillole.org

Drug merger strengthens local plant  -  Apr 29, 2005
For the last five years, the plant has produced Protopic ointment, ... If Protopic manufacturing expands, the plant is big enough to handle the extra volume ... Buffalo Business First

Brand Names/Synonyms:
Protopic is also known by the following brand names and/or synonymsFK 506; FK-506; FK5; K506; Prograf; Protopic; Tacarolimus; Tacrolimus

Drug Category:
Protopic is categorized under the following by the FDA: Immunosuppressive Agents; ATC:D11AX14; ATC:L04AA05

Dosage Forms:
CAPSULE; OINTMENT; SOLUTION

Absorption:
Generally incomplete with absolute bioavailability of 17-22%

Interactions:
[an error occurred while processing this directive]



Chemical IUPAC Name:
[3S-[3R*[E(1S*,3S*,4S*)],4S*,5R*,8S*,9E,12R*,14R*,15S*,16R*,18S*,19S*,26aR*]]-5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-hexadecahydro-5, 19-dihydroxy-3- [2-(4-hydroxy-3-methoxycyclohexyl) -1-methylethenyl]-14, 16-dimethoxy-4,10,12,18-tetramethyl-8-(2-propenyl)-15, 19-epoxy-3H-pyrido[2,1-c][1,4] oxaazacyclotricosine-1,7,20, 21(4H,23H)-tetrone, monohydrate





Health Home | Conditions | Cancer | Medications | Surgery | Vaccines


The Cancer News Network


Disclaimer:

Contact a physician with regard to health concerns. Email requests for further health information will be discarded.

The materials contained on this Web site are for informational purposes only and do not constitute health or medical advice. Use of information on this site does not create or constitute any kind of agreement or contract between you and the owners or users of this site, the owners of the servers upon which it is housed, or anyone else who is in any way connected with this site.

Many links on cancernewsnetwork.org lead to other sites. cancernewsnetwork.org does not sponsor, endorse or otherwise approve of the materials appearing in such sites. Nor is CancerNewsNetwork.org responsible for dead or misdirected links.

IF YOU NEED A LINK OR TEXT REMOVED FROM THIS PAGE PLEASE CONTACT cancernewsnetwork (at) live.com.
We will do our best to accommodate your request.



COPYRIGHT 2009 CANCERNEWSNETWORK | Privacy