Quetiapine

This page contains recent news articles, when available, and an overview of Quetiapine but does not offer medical advice. You should contact your physician with regard to any health issues or concerns.


Overview:

Quetiapine
(when available)

Pharmacology and use:
Quetiapine is a psychotropic agent belonging to the chemical class of benzisoxazole derivatives and is indicated for the treatment of schizophrenia. Quetiapine is a selective monoaminergic antagonist with high affinity for the serotonin Type 2 (5HT2), and dopamine type 2 (D2) receptors. Quetiapine is an antagonist at serotonin 5-HT1A and 5HT2, dopamine D1 and D2, histamine H1, and adrenergic alpha 1 and alpha 2 receptors. Quetiapine has no significant affinity for cholinergic muscarinic or benzodiazepine receptors. Drowsiness and orthostatic hypotension associated with use of quetiapine may be explained by its antagonism of histamine H1 and adrenergic alpha 1 receptors, respectively. Quetiapine's antagonism of adrenergic a1 receptors may explain the orthostatic hypotension observed with this drug. For the treatment of schizophrenia and acute manic episodes associated with bipolar I disorder, as either monotherapy or adjunct therapy to lithium or divalproex.

Mechanism Of Action:
The mechanism of action of quetiapine, as with other drugs used to treat schizophrenia, is unknown. However, it is thought that the drug's therapeutic activity in schizophrenia is mediated through a combination of dopamine type 2 (D2) and serotonin type 2 (5HT2) receptor antagonism. Although quetiapine is known to bind other receptors with similar affinity, only the dopamine D2 and serotonin 5HT2 receptor binding is responsible for quetiapine's therapeutic activity in schizophrenia.

News Articles on Quetiapine

Corcept Therapeutics Announces Four Anticipated Milestones for 2010  -  05 Jan 2010
The group of medications known as atypical antipsychotics, including olanzapine, risperidone, clozapine and quetiapine, are widely used to treat ... CNNMoney.com (press release)

Antipsychotic Use Among Young Children Up Despite Risks and Questions  -  05 Jan 2010
Atypical antipsychotics generate more than $12 billion in sales every year, with Seroquel (quetiapine fumarate) leading the pack with nearly $4.45 billion ... AboutLawsuits.com

Atypical Antipsychotics Increase Cardiometabolic Risk in Children  -  ‎Dec 29, 2009‎
After approximately 11 weeks, there was a mean weight gain of 8.5 kg with olanzapine, 6.1 kg with quetiapine, 5.3 kg with risperidone, and 4.4 kg with ... Psychiatric Times

AstraZeneca welcomes FDA decision on CRESTOR  -  ‎Dec 16, 2009‎
Earlier this month, the company announced that the FDA has approved once-daily SEROQUEL XR (quetiapine fumarate) extended release tablets as an add-on ... Zenopa

Antipsychotic Use and Risk for Hyperglycemia in Elderly Patients With DM  -  ‎Dec 14, 2009‎
First, the included drugs in the atypical group consisted not of the 6 aforementioned drugs but only of 3 drugs (olanzapine, quetiapine, and risperidone). ... Archives of Internal Medicine

Which Antidepressant Is Right for a Given Patient?  -  ‎Dec 29, 2009‎
...[3] If the patient has an anxiety or substance abuse component in his or her Axis 2, perhaps an atypical antipsychotic such as quetiapine may be used. ... Medscape

Psychiatry: Science or Science Fiction?  -  ‎Dec 23, 2009‎
..."The addition of aripiprazole to risperidone or quetiapine was not associated with improvement in psychiatric symptoms but was generally safe and well ... Gather.com

"Naughty" Pharma Still Got Christmas Presents From FDA in 2009  -  ‎Dec 31, 2009‎
...agents," says the DPV report in addition to "a number of lawsuits against olanzapine [Zyprexa] and quetiapine [Seroquel] involving metabolic effects. ... NewsBlaze

Antipsychotic Prescribing in Children: What We Know—What We Need to Know  -  ‎Dec 16, 2009‎
...all naive to antipsychotic medications, was followed for approximately 10 weeks after initiating treatment with olanzapine, risperidone, quetiapine, ... Psychiatric Times

Pharmacotherapy for borderline personality disorder: Cochrane systematic ...  -  ‎Dec 31, 2009‎
Additionally, there are findings from lower-level evidence studies on further FGAs and SGAs (eg trifluoperazine, clozapine, quetiapine, risperidone), ... British Journal of Psychiatry

Should you take Seroquel XR to treat depression?  -  ‎Dec 29, 2009‎
...version of quetiapine (Seroquel XR) – recently gained FDA approval for the treatment of depression that hasn't responded to an antidepressant alone. ... Seattle Post Intelligencer (blog)

Overdose prompts coronor's inquest  -  ‎Dec 16, 2009‎
An autopsy found he had died from an overdose of Quetiapine, a derivative of the prescription drug Seroquel which he had been prescribed for depression. ... Toowoomba Chronicle

Use Of Antipsychotic Medications By Children And Adolescents Associated With ...  -  ‎Oct 28, 2009‎
Patients were treated with the antipsychotic medications aripiprazole, olanzapine, quetiapine, or risperidone for 12 weeks. After a median (midpoint) of ... Science Daily (press release)

Antipsychotic drugs tied to weight gain in children  -  ‎Nov 3, 2009‎
Two drugs, olanzapine and quetiapine, were linked to higher cholesterol and triglyceride levels, which are risk factors for metabolic syndrome. ... Boston Globe

Weight gain worries over psychiatric drugs for children  -  ‎Oct 28, 2009‎
Children who'd taken olanzapine and quetiapine had worsened cholesterol levels and also higher levels of a group of fats called triglycerides. ... guardian.co.uk

AstraZeneca to Pay $520 Million to Resolve Seroquel Dispute  -  ‎Nov 11, 2009‎
...including California and Arkansas, that have sued or investigated the company over its alleged off-label promotion of Seroquel (quetiapine fumarate) and ... FDA news (subscription)

Children Gain Weight on Antipsychotic Medications  -  ‎Oct 31, 2009‎
Average gain was as follows: 18.7 pounds with onanzapine, 13.7 pounds with quetiapine, 11.7 pounds with risperidone, and 9.7 pounds with aripiprazole. ... Healia Health (blog)

30 to 40 % of mental illnesses in UAE are schizophrenia-related  -  ‎Oct 31, 2009‎
Leading doctors practicing in the UAE threw light on mental illnesses prevailing in the country and discussed the effectiveness of Quetiapine Sustained ... Al-Bawaba

The Puzzling Difference Between Schmutz X and Compound 24028 in AstraZeneca  -  ‎Oct 27, 2009‎
Teva Pharmaceuticals, Inc. to make you reach for an antipsychotic drug like quetiapine which is at the heart of this case. For those who are unfamiliar with ... IPWatchdog.com

AstraZeneca close to settling Seroquel investigations in USA  -  ‎Oct 30, 2009‎
The US Attorney's Office in Philadelphia has been directing an investigation relating to Seroquel (quetiapine) involving a review of sales and marketing ... Pharma Times

Antipsychotic Drugs Put Kids at Risk  -  ‎Nov 1, 2009‎
After about 11 weeks of treatment, patients on average had gained 18.7 pounds with olanzapine, 13.4 pounds with quetiapine, 11.7 pounds with risperidone and ... Ivanhoe

Corcept Therapeutics Announces Recent Highlights and Third Quarter 2009 ...  -  ‎Nov 10, 2009‎
The group of medications known as atypical antipsychotics, including olanzapine, risperidone, clozapine and quetiapine, are widely used to treat ... CNNMoney.com (press release)

Children on antipsychotic drugs more prone to diabetes: Canadian study  -  ‎Nov 11, 2009‎
The medications include risperidone, quetiapine, olanzapine and clozapine, used to treat aggression or mood changes, attention deficit, developmental delays ... Vancouver Sun

Is Your Doctor's Continuing Ed Funded by Pharma?  -  ‎Nov 7, 2009‎
Study of Quetiapine in Combination With Lithium or Divalproex� in the American Journal of Psychiatry (AJP) by CME presenter Trisha Suppes fare well. ... The Epoch Times

Is Your Doctor's Continuing Ed Funded by Pharma?  -  ‎Nov 4, 2009‎
Study Of Quetiapine In Combination With Lithium Or Divalproex� in the American Journal of Psychiatry (AJP) by CME presenter Trisha Suppes fare well. ... Dissident Voice

Dropouts and Missing Data in Psychiatric Clinical Trials  -  ‎Nov 2, 2009‎
...it would be difficult to interpret the early responses to paliperidone therapy at day 5 relative to quetiapine (p<0.05) and placebo (p<0.001) (2). ... Am J Psychiatry (subscription)

Bipolar drug market “to plummet from 2011â€?  -  ‎Nov 10, 2009‎
...by the patent expiries and subsequent generic erosion of a number of key antipsychotic agents including AstraZeneca's Seroquel (quetiapine fumarate), ... Pharma Times

This Week in JAMA  -  ‎Oct 27, 2009‎
Correll and colleagues (SEE ARTICLE) assessed the association of 12-week treatment with aripiprazole, olanzapine, quetiapine, or risperidone with body ... Journal of American Medical Association (subscription)

IDF: Diabetes Plus Schizophrenia Increases Risk of Heart Disease  -  ‎Oct 22, 2009‎
The current first-line treatments for schizophrenia are the atypical antipsychotic agents, such as clozapine, olanzapine, quetiapine, risperidone, ... MedPage Today

Anti-Psychotic Medications Associated With Childhood Weight Gain  -  ‎Oct 28, 2009‎
Specifically, an average of 18.7 pounds with olanzapine, by 13.4 pounds with quetiapine, by 11.7 pounds with risperidone and by 9.7 lbs. with aripiprazole, ... Gant Daily

AstraZeneca withdraws filings for lung cancer drug  -  ‎Nov 2, 2009‎
...on drug such as gastrointestinal Nexium (esomeprazole), Seroquel (quetiapine) for schizophrenia and cholesterol-lowerer Crestor (rosuvastatin). ... Pharmafocus

Bipolar II Postpartum Depression: Detection, Diagnosis, and Treatment  -  ‎Nov 2, 2009‎
There is preliminary evidence supporting the use of quetiapine during breastfeeding (22), even though data on the safety of the atypical antipsychotics in ... Am J Psychiatry (subscription)

New systematic study for managing treatment-resistant bipolar depression  -  ‎Oct 27, 2009‎
...lamotrigine plus lithium, mood stabilizers plus multiple antidepressants, plus trials with olanzapine and quetiapine, and a trial of pramipexole. ... News-Medical.net

VIDEO: Second Generation Antipsychotic Drugs Show Almost Immediate Unwanted ...  -  ‎Oct 27, 2009‎
Two of the drugs – olanzapine and quetiapine – were associated with increases in total cholesterol, non-HDL cholesterol, and the ratio of triglycerides to ... Insidermedicine

Orion Group Interim Report January-September 2009  -  ‎Oct 26, 2009‎
For example, the anti-psychotic drug Ketipinor(R) (quetiapine) and the cholesterol-lowering drug Atorvastatin Orion(R) (atorvastatin) have been particularly ... Trading Markets (press release)

Secret Documents Reveal AstraZeneca Knowingly Promoted Psych Drugs for ...  -  ‎Oct 28, 2009‎
Seroquel (generic name quetiapine) was approved for the treatment of psychotic disorders in adults in 1997. In 2001, the FDA extended this approval to cover ... Prison Planet.com

Nieuwe mogelijkheid onderhoudsbehandeling bipolaire stoornis  -  ‎Nov 11, 2009‎
Het College ter Beoordeling van Geneesmiddelen (CBG) heeft Seroquel XR® (quetiapine, éénmaal daags) goedgekeurd als geneesmiddel voor de behandeling van de ... Medical facts

Des antipsychotiques provoquent l'obésité chez les enfants et les adolescents  -  ‎Nov 2, 2009‎
Ils se sont tous vus prescrire quatre différents types d'antipsychotiques à savoir l'aripiprazole, l'olanzapine, le quetiapine et le risperidone pendant 12 ... Algérie Soir

æ—¥ 제네릭 시장 '외ìž?사 진출러시'  -  ‎Nov 2, 2009‎
...pramipexole)ê°€, 2012ë…„ì—” '아리미ë?±ìФ'(Arimidex, anastrozole), 'ì½”ìž?'(Cozaar, losartan), '쎄로켈'(Seroquel, quetiapine), '파리ì—?트'(Pariet, rabeprazole), ... 디지틀보사

Les antipsychotiques causent un rapide et important gain de poids chez les jeunes  -  ‎Oct 27, 2009‎
...pour la première fois, un des quatre antipsychotiques Abilify (aripiprazole), Risperdal (risperidone), Seroquel (quetiapine) ou Zyprexa (olanzapine). ... PsychoMédia

Les anti-psychotiques pour enfants créent des problèmes de poids  -  ‎Oct 28, 2009‎
Chez les enfants et les adolescents, les médicaments antipsychotiques atypiques conduisent à un gain marquée et rapide de poids, selon les chercheurs. ... Le blog bébé (Blog)

Concerns over Alzheimer's drug  -  Feb 18, 2005
Quetiapine (Seroquel) is commonly used in nursing homes to combat ... Antipsychotic drugs such as quetiapine are used in up to 45% of nursing homes to treat ... BBC News

Quetiapine ineffective for dementia with parkinsonism  -  May 10, 2007
By David Douglas. NEW YORK (Reuters Health) - The antipsychotic drug quetiapine (Seroquel) is of limited use in treating agitation or psychosis in patients ... Reuters

Studies Compare New Antipsychotic Drugs  -  Mar 2, 2007
FRIDAY, March 2 (HealthDay News) -- The antipsychotic drug quetiapine and, ... Patients taking quetiapine stayed on the drug for an average of 10 months ... Washington Post

Antipsychotics curb violence in some schizophrenics  -  Jul 3, 2008
..."In fact, one of the newer medications, quetiapine, performed worse than the first-generation drug perphenanize," Dr. Jeffrey W. Swanson, ... Reuters

… Disorder: Pivotal Study Confirms Potential of Quetiapine as First...  -  May 24, 2006
The results of a pivotal study confirm the potential of quetiapine fumarate ... Quetiapine is an atypical anti-psychotic and it is already established as an ... Newswit.com

Warning over 'chemical cosh' dementia drugs  -  Feb 23, 2005
Compared with patients on a placebo, those taking quetiapine had a doubled rate of decline in mental abilities while those on rivastigmine showed no ... Telegraph.co.uk

The Nation; Older Drug Is Best for Schizophrenia; But no option...  -  Apr 1, 2006
...olanzapine or risperidone were able to tolerate the drugs, compared with 23% of those who took ziprasidone and 16% of those who received quetiapine. ... Pay-Per-View - Los Angeles Times - ProQuest Archiver

Seroquel® (Quetiapine) Sustained Release Schizophrenia Data Show …  -  Mar 19, 2007
AstraZeneca today announced clinical trial data presented at the European Congress of Psychiatry (ECP) in Madrid that found the once-daily quetiapine ... Medical News Today - Medical News Today (press release)

Quetiapine XR Shown to Improve Quality of Life of Patients With …  -  Mar 10, 2008
By Mike Fillon. SAVANNAH, Ga -- March 10, 2008 -- The onset of action of quetiapine XR monotherapy (50 and 150 mg/day) for the treatment of generalised ... DG News

Quetiapine Shows Promising Results for Treatment of Generalized …  -  Mar 27, 2006
By Fran Lowry. MIAMI, FL -- March 27, 2006 -- Two studies presented here at the 26 th annual conference of the Anxiety Disorders Association of America ... DG News

Quetiapine Extended-Release May Be Effective for Generalized Anxiety ...  -  May 9, 2008
By Charlene Laino. WASHINGTON, DC -- May 9, 2008 -- Extended-release (ER) quetiapine monotherapy may help decrease symptoms of anxiety in patients with ... DG News

Studies focus on schizophrenia treatment  -  Mar 1, 2007
Researchers found quetiapine, and to some extent olanzapine, might be more effective ... Researchers found patients taking quetiapine stayed on the longest, ... United Press International

Quetiapine and EPS.(EVIDENCE-BASED PSYCHIATRIC MEDICINE)  -  Feb 1, 2008
How likely is it that this patient actually needs trihexyphenidyl, a medication wanted by inmates for its abuse potential? In other words, what is the ... Free with registration - Clinical Psychiatry News - AccessMyLibrary.com

Quetiapine may help manage depression in bipolar adolescents.(care …  -  Apr 1, 2006
TORONTO -- Quetiapine appears to improve symptoms of depression and suicidal ideation in adolescents with bipolar disorder, mood disorder, ... Free with registration - Clinical Psychiatry News - AccessMyLibrary.com

Quetiapine-Induced Weight Gain and Escitalopram  -  Jan 22, 2005
TO THE EDITOR: Quetiapine-induced weight gain in an adolescent girl started with treatment with adjunctive escitalopram only. A slight decrease in weight ... RedOrbit

Extended-Release Quetiapine Effective in Treating Acute Schizophrenia:...  -  May 24, 2007
By Paula Moyer. SAN DIEGO, CA -- May 24, 2007 -- A once-daily extended-release formulation of quetiapine (Seroquel) is effective in the treatment of acute ... DG News

Trial Shows Efficacy and Tolerability of Quetiapine and Olanzapine in...  -  Sep 20, 2006
By Chris Berrie. PARIS, FRANCE -- September 20, 2006 -- The second-generation antipsychotics quetiapine and olanzapine show similar efficacies and ... DG News

Article: Quetiapine: not for AD agitation.(Geriatrics)(Brief Article)...  -  Apr 15, 2005
Quetiapine: not for AD agitation.(Geriatrics)(Brief Article) ... find Internal Medicine News articles. Neither rivastigmine nor quetiapine appears effective ... Pay-Per-View - Internal Medicine News - HighBeam Research

Quetiapine fails to reduce agitation/psychosis in patients with...  -  Jul 1, 2007
Quetiapine showed no efficacy for reducing agitation and psychosis in patients with dementia with Lewy bodies, Parkinson disease with dementia, ... Free with registration - Brown University Geriatric Psychopharmac... - AccessMyLibrary.com

Acute respiratory failure and quetiapine.(Adverse Events)  -  Jul 1, 2006
Quetiapine (Seroquel[R]) is one member of a growing list of atypical antipsychotic agents used in the treatment of psychosis in patients with schizophrenia ... Free with registration - Brown University Geriatric Psychopharmac... - AccessMyLibrary.com

Does Quetiapine Produce False-Positive Methadone Tests?  -  Jan 15, 2008
Can you discuss the reports of alleged false-positive methadone blood tests attributed to quetiapine (Seroquel)? Methadone urine drug screens use ... Medscape

Quetiapine Monotherapy Controls Bipolar II Depression: Presented at …  -  Oct 26, 2005
By Paula Moyer. AMSTERDAM, THE NETHERLANDS -- October 26, 2005 -- Patients with bipolar II depression get sufficient relief from quetiapine (Seroquel) that ... DG News

Quetiapine and quality of life in bipolar depression.(What's New in …  -  Mar 1, 2007
In a new report on the effects of quetiapine (Seroquel) on quality of life (QOL) improvements in adults with bipolar depression, Endicott and colleagues ... Free with registration - Brown University Psychopharmacology... - AccessMyLibrary.com

… Schizophrenia Exacerbations Faster Than Quetiapine: Presented at...  -  Jul 18, 2008
Changes in PANSS scores were not significantly different in the paliperidone and quetiapine arms during the first 4 days of monotherapy, but beginning on ... DG News

FDA Approves Seroquel(R) (Quetiapine Fumarate) for Bipolar Depression...  -  Oct 20, 2006
LONDON, UK -- October 20, 2006 -- AstraZeneca today announced that the US Food and Drug Administration (FDA) approved Seroquel® (quetiapine fumarate) for ... DG News

Neuroleptic Malignant Syndrome Induced By Quetiapine and …  -  Apr 23, 2005
TO THE EDITOR: Neuroleptic malignant syndrome is induced less by atypical antipsychotics than by conventional antipsychotics, and one particular atypical ... RedOrbit

Quetiapine facilitates oligodendrocyte development and prevents mice ...  -  Aug 7, 2007
Correspondence: Dr XM Li, Current address: Department of Psychiatry, University of Manitoba, PZ432-771 Bannatyne Ave., Winnipeg, MB, Canada R3E 3N4. ... Nature.com

Safety and Tolerability of Quetiapine in Children and Adolescents...  -  Nov 6, 2008
By Laura Gater. CHICAGO -- November 6, 2008 -- Quetiapine therapy appears to increase the level of function of children and adolescents with bipolar I ... DG News

Quetiapine (Systemic).(Used to treat psychotic disorders)(Drug...  -  Aug 1, 2006
Quetiapine (kwe-TYE-a-peen ) is used to treat psychotic disorders, such as schizophrenia. This medicine has NOT been approved to treat behavioral problems ... Free with registration - USP DI-Volume II, Advice for the... - AccessMyLibrary.com

Blood Dyscrasia With Quetiapine and Ziprasidone  -  Feb 3, 2005
To THE EDITOR: Pharmaceutically induced blood dyscrasias with bone marrow suppression from antipsychotic drugs are a subject of current concern. ... RedOrbit

Quetiapine Combined With Naltrexone Does Not Enhance Efficacy for …  -  Oct 23, 2007
By Paula Moyer. VIENNA, AUSTRIA -- October 23, 2007 -- Patients do not receive any additional efficacy benefits when they receive quetiapine in addition to ... DG News

Quetiapine and EPS.(EVIDENCE-BASED PSYCHIATRIC MEDICINE) | …  -  Feb 1, 2008
Quetiapine and EPS.(EVIDENCE-BASED PSYCHIATRIC MEDICINE) ... find Clinical Psychiatry News articles. The Problem An inmate-patient at the state prison in ... Pay-Per-View - Clinical Psychiatry News - HighBeam Research

Quetiapine equal to divalproex for adolescent mania.(What's New In …  -  Jul 1, 2006
The results of this 28-day double-blind randomized pilot study suggest that quetiapine (Seroquel) is equally as effective as divalproex (Depakote) in the ... Free with registration - Brown University Child and Adolescent... - AccessMyLibrary.com

Seroquel (brand): Quetiapine (generic).(Your Medication Information)  -  Mar 1, 2005
COMMON USAGE: Quetiapine is used for the treatment of schizophrenia; it is also indicated for the short-term treatment of acute manic episodes associated ... Free with registration - Psychopharmacology Update - AccessMyLibrary.com

Quetiapine Widely Used Off-Label in Psychiatric Inpatients  -  May 24, 2007
May 24, 2007 (San Diego) — A recent study found that among patients in a psychiatric hospital, the atypical antipsychotic quetiapine (Seroquel, AstraZeneca) ... Medscape

Quetiapine Treats Bipolar Depression without Inducing Manic or …  -  Nov 10, 2005
By Steve Pridgeon. VANCOUVER, CANADA -- November 10, 2005 -- Bipolar depression can be treated with adjunctive quetiapine, without inducing manic or ... DG News

… Determination That SEROQUEL (Quetiapine Fumarate) Tablets, 150  -  Jan 25, 2008
SEROQUEL (quetiapine fumarate) tablets are in a class of medications called ... SEROQUEL (quetiapine fumarate) tablets may be used alone or with lithium or ... Pay-Per-View - Federal Register 2008 - Loislaw

… Efficacy and Superior Tolerability of Quetiapine Compared to...  -  Jan 4, 2006
This small, but tightly controlled pilot study shows that quetiapine and ... Patients treated with quetiapine had a significantly lower incidence of EPS, ... DG News

Quetiapine Sustained Release Schizophrenia Data Show Relapse …  -  Apr 2, 2007
AstraZeneca today announced clinical trial data presented at the European Congress of Psychiatry (ECP) in Madrid that found the once-daily quetiapine ... Virtual Medical Centre - The Virtual Medical Centre

… Efficacy and Superior Tolerability of quetiapine Compared to...  -  Apr 1, 2006
This small, but tightly controlled pilot study shows that quetiapine and ... Patients treated with quetiapine had a significantly lower incidence of EPS, ... presseportal.de

Quetiapine speeds up rate of decline in Alzheimers  -  Feb 20, 2005
Quetiapine, a drug commonly used in nursing homes to treat agitation and related symptoms in people with Alzheimers' disease actually worsens patients' ... News-Medical.net

Seroquel XL (Quetiapine Prolonged Release): A Once Daily Formulation ...  -  Sep 15, 2008
AstraZeneca has developed the new formulation of its atypical antipsychotic treatment to meet the needs of patients for whom a once daily dose is preferred ... Medical News Today - Medical News Today (press release)

How to take Quetiapine from Consumer Reports Health.  -  Jan 8, 2007
Use in Older Adults: Studies have shown that older adults with dementia (a brain disorder that ... Full Alert. tell your doctor and pharmacist if you are ... consumerreports.org

Quetiapine, Divalproex Equally Effective in Adolescent Bipolar With...  -  Oct 25, 2005
Oct. 25, 2005 (Toronto) — Adolescents with both bipolar disorder and a disruptive behavior disorder get equal relief from their aggressive symptoms with ... Medscape

Quetiapine Monotherapy Has Benefits for Treatment of Generalized …  -  May 29, 2006
By Danny Kucharsky. TORONTO, CANADA -- May 29, 2006 -- Quetiapine may be a useful option for the treatment of generalized anxiety disorder (GAD), ... DG News

Learn about Quetiapine from Consumer Reports Health.  -  Jan 8, 2007
Use in Older Adults: Studies have shown that older adults with dementia (a brain disorder that ... Full Alert. Quetiapine is used to treat the symptoms of ... consumerreports.org

… Behavior Respond Equally Well to Quetiapine and Divalproex:...  -  Oct 31, 2005
Patients were randomized to received quetiapine or divalproex in a ... Those in the quetiapine group received an initial dose of 100 mg per day on day 1, ... DG News

AstraZeneca Submits Seroquel XRâ„¢ in Europe for the Treatment of Major...  -  Jun 11, 2008
Data from eight randomised placebo-controlled studies of quetiapine XR at once-daily ... The short-term studies demonstrated that quetiapine XR reduced ... webwire.com

Quetiapine may ease mania in teens.(research, care and treatment)(Brie...  -  Apr 1, 2006
Quetiapine was at least as effective as divalproex in alleviating manic symptoms in adolescents in a randomized, double-blind pilot study, wrote Dr. Melissa ... Free with registration - Clinical Psychiatry News - AccessMyLibrary.com

Quetiapine and venlafaxine intoxication.(Drug-Drug Interactions)  -  Feb 1, 2005
Venlafaxine (Effexor) and quetiapine (Seroquel) are two psychotropic agents generally considered to have better safety profiles than those from earlier ... Free with registration - Brown University Psychopharmacology... - AccessMyLibrary.com

Extended-release quetiapine maintained antianxiety effects.(Psychiatry...  -  Nov 1, 2008
Extended-release quetiapine maintained antianxiety effects.(Psychiatry) ... find Internal Medicine News articles. Phoenix -- The extended-release form of ... Pay-Per-View - Internal Medicine News - HighBeam Research

The Use of Imaging in the Early Development of Neuropharmacological …  -  Jun 28, 2007
Identifying a rational dosing interval for quetiapine. Quetiapine is an example of the use of imaging during the early drug development to identify a ... Nature.com

Quetiapine has efficacy for adolescent mania.(Disease/Disorder...  -  May 1, 2006
Quetiapine was at least as effective as divalproex in alleviating manic symptoms in adolescents in a randomized, double-blind pilot study, wrote Dr. Melissa ... Free with registration - Internal Medicine News - AccessMyLibrary.com

Atypical Antipsychotics May Offer Benefits for AD  -  Jun 2, 2005
Of the three study drugs and placebo, olanzapine and risperidone had the fewest discontinuations due to effectiveness, whereas the placebo and quetiapine ... Medscape

Biovail Announces Filing of ANDA for Quetiapine XR Tablets  -  Dec 1, 2008
Biovail Corporation (NYSE:BVF) (TSX:BVF) today announced that the United States Food and Drug Administration (FDA) has accepted the Company's abbreviated ... International Business Times

Taking Quetiapine from Consumer Reports Health.  -  Jan 8, 2007
Use in Older Adults: Studies have shown that older adults with dementia (a brain disorder that ... Full Alert. Quetiapine may cause side effects. ... consumerreports.org

Psychiatric Times.  -  Aug 1, 2006
Analysis of dropouts in patients who received quetiapine also showed higher rates of ... Those who may respond best to quetiapine are typically agitated, ... Psychiatric Times

New era for SEROQUEL® (quetiapine fumarate) - approval from the FDA  -  May 19, 2008
With the acceptance of SEROQUEL® (quetiapine fumarate) by the FDA to treat Bipolar disorder, medical research can yet again rely on extensive clinical ... Gerson Lehrman Group

Low Cortisol Caused by Quetiapine: Presented at APA  -  May 23, 2007
By Kristina R. Anderson. SAN DIEGO, CA -- May 23, 2007 -- Some patients taking the atypical antipsychotic quetiapine (Seroquel) are being diagnosed with ... DG News

Atypical quetiapine appears to reduce bipolar depression.(Rx) |...  -  May 1, 2005
Atypical quetiapine appears to reduce bipolar depression.(Rx) ... find Internal Medicine News articles. SAN DIEGO -- The atypical antipsychotic quetiapine ... Pay-Per-View - Internal Medicine News - HighBeam Research

Quetiapine treatment for pediatric Tourette's Syndrome.(News Notes)( …  -  Mar 1, 2007
Quetiapine may be a safe and effective treatment for children and adolescents with Tourette's Syndrome (TS). According to a small, 8-week retrospective ... Free with registration - Brown University Child and Adolescent... - AccessMyLibrary.com

Studies Examine Quetiapine Fumarate in Combination With …  -  May 30, 2006
WILMINGTON, DE -- May 30 2006 -- AstraZeneca announced results of two clinical studies that examined Seroquel(R) (quetiapine fumarate) in combination with ... DG News

New data for quetiapine (Seroquel).(News from the APA Annual Meeting ...  -  Jul 1, 2005
According to new data from an 8-week, double-blind, placebo-controlled trial of quetiapine, significant improvement was seen in quality of life measures ... Free with registration - Brown University Psychopharmacology... - AccessMyLibrary.com

Quetiapine Well Tolerated in Adolescents With Mood Disorders at Risk...  -  Nov 3, 2006
By Paula Moyer. SAN DIEGO, CA -- November 3, 2006 -- Adolescents with mood disorders who are at risk of bipolar disorder respond well to quetiapine ... DG News

CAFE Study Shows Varying Benefits Among Atypical Antipsychotics  -  Oct 25, 2005
There were 134 patients in the quetiapine group and 133 each in the olanzapine and ... The average doses were 11.7 mg for olanzapine, 506 mg for quetiapine, ... Medscape

Quetiapine monotherapy appears effective for bipolar II depression.(ca...  -  Nov 1, 2005
Quetiapine monotherapy appears effective for bipolar II depression.(care and treatment)(Statistical data) ... find Clinical Psychiatry News articles. Pay-Per-View - Clinical Psychiatry News - HighBeam Research

Dementia patients warned off new drugs  -  Jun 16, 2005
The warning relates to four drugs - olanzapine (Zyprexa), risperidone (Risperdal), quetiapine (Seroquel) and clozapine (Clozaril) - and was issued yesterday ... Pay-Per-View - Toronto Star - ProQuest Archiver

Antipsychotic Drug; Disposition of quetiapine in determined specimens...  -  Apr 4, 2005
2005 APR 4 - (NewsRx.com) -- Researchers have determined the disposition of quetiapine in biological specimens from postmortem cases. ... Pay-Per-View - Health & Medicine Week - Factiva, from Dow Jones

Quetiapine bests paroxetine in bipolar trial.(Adult Psychiatry)(Clinic...  -  Oct 1, 2008
Quetiapine bests paroxetine in bipolar trial.(Adult Psychiatry)(Clinical report) ... find Clinical Psychiatry News articles. Pay-Per-View - Clinical Psychiatry News - HighBeam Research

Diffuse muscle pain with quetiapine  -  Jan 9, 2005
KNF has participated in field trials sponsored by Eli Lilley & Co. and by Astra-Zeneca. We report the case of a 28-year-old female out-patient with bipolar ... British Journal of Psychiatry (subscript...

Antipsychotic Drug; Disposition of quetiapine in determined specimens...  -  Apr 9, 2005
2005 APR 9 - (NewsRx.com) -- Researchers have determined the disposition of quetiapine in biological specimens from postmortem cases. ... Pay-Per-View - Obesity, Fitness & Wellness Week - Factiva, from Dow Jones

Clozapine 'wins again' in phase II of CATIE.(drug usage)(clinical...  -  May 1, 2006
Clozapine did significantly better than quetiapine and risperidone (overall P value .028), but not olanzapine. At the same time olanzapine was neither ... Free with registration - Clinical Psychiatry News - AccessMyLibrary.com

Study Sheds Light on Value of Newer Antipsychotic Drugs for …  -  Mar 6, 2007
Those taking quetiapine stayed on the longest — averaging about 10 months ... While none of those patients taking quetiapine discontinued use due to weight ... newswise.com

New Antipsychotic Meds Have Value  -  Mar 8, 2007
Those taking quetiapine stayed on the longest — averaging about 10 months ... While none of those patients taking quetiapine discontinued use due to weight ... PsychCentral.com

… and Compliance With SEROQUEL(R) (quetiapine fumarate) Examined in …  -  May 23, 2005
Cognitive Function and Compliance With SEROQUEL(R) (quetiapine fumarate) Examined in Separate Studies in Patients With Schizophrenia. from PR Newswire. Pay-Per-View - PR Newswire - HighBeam Research

… Efficacy and Superior Tolerability of quetiapine Compared to...  -  Jan 4, 2006
Article: Quetiapine efficacy equal to risperidone.(Brief Article) Pharma Marketletter; January 9, 2006 ; 700+ words ... ... predominately negative symptoms, ... Pay-Per-View - PR Newswire Europe - HighBeam Research

Quetiapine effective for acute bipolar mania in older adults.(care...  -  Jan 1, 2006
Quetiapine effective for acute bipolar mania in older adults.(care and treatment) ... find Clinical Psychiatry News articles. Pay-Per-View - Clinical Psychiatry News - HighBeam Research

Article: Atypical quetiapine appears effective for bipolar depression....  -  Aug 1, 2005
Atypical quetiapine appears effective for bipolar depression.(Adult Psychiatry) ... find Clinical Psychiatry News articles. SAN DIEGO -- The atypical ... Pay-Per-View - Clinical Psychiatry News - HighBeam Research

Quetiapine effective in reducing aggression & violent behaviour in …  -  Jun 20, 2005
By AstraZeneca, [RxPG] A new study, published today in the journal Human Psychopharmacology: Clinical and Experimental,1 shows that the atypical ... RxPG NEWS

BOLDER II (BipOLar DEpRession) study - Quetiapine effective in...  -  Oct 24, 2005
By AstraZeneca, Newly released top-line results from the BOLDER II (BipOLar DEpRession) study have underlined the potential for SEROQUEL (quetiapine ... RxPG NEWS

Bloomberg Printer-Friendly Page  -  Jan 2, 2008
Quetiapine should be prescribed in a manner that is most likely to minimize ... In long-term clinical trials of quetiapine, hyperglycemia (fasting glucose ... Bloomberg

Neuroscienze PharmaNess SCaRL; Quetiapine elevates noradrenaline …  -  Jan 26, 2005
2005 JAN 26 - (NewsRx.com & NewsRx.net) -- Quetiapine elevates both noradrenaline and dopamine release in the rat prefrontal cortex. ... Pay-Per-View - Biotech Week - Factiva, from Dow Jones

Mental Health; Quetiapine elevates noradrenaline and dopamine release...  -  Jan 24, 2005
2005 JAN 24 - (NewsRx.com & NewsRx.net) -- Quetiapine elevates both noradrenaline and dopamine release in the rat prefrontal cortex. ... Pay-Per-View - Health & Medicine Week - Factiva, from Dow Jones

Mental Health; Quetiapine elevates noradrenaline and dopamine release...  -  Jan 28, 2005
2005 JAN 28 - (NewsRx.com & NewsRx.net) -- Quetiapine elevates both noradrenaline and dopamine release in the rat prefrontal cortex. ... Pay-Per-View - Drug Week - Factiva, from Dow Jones

Atypical Antipsychotics Have Very Different Adverse Effect Profiles...  -  Mar 13, 2006
3 As reflected in our sample, there is less experience with quetiapine ... Only 1 published clinical trial has evaluated quetiapine in the context of BPSD, ... Archives of Internal Medicine

… , DE) antipsychotic Seroquel (quetiapine) worsened Alzheimer's...  -  Apr 1, 2005
AstraZeneca's (Wilmington, DE) antipsychotic Seroquel (quetiapine) worsened Alzheimer's patients, according to a study at King's College of London. Free with registration - Applied Clinical Trials - AccessMyLibrary.com

… study of AstraZeneca's (Wilmington, DE) Seroquel (quetiapine).(Phas...  -  Jul 1, 2005
A postmarketing study of AstraZeneca's (Wilmington, DE) Seroquel (quetiapine) showed it may be an effective treatment for aggression in schizophrenia. Free with registration - Applied Clinical Trials - AccessMyLibrary.com

AstraZeneca's schizophrenia drug gets the nod in the Netherlands  -  Aug 30, 2007
Seroquel XR (quetiapine fumerate), a once-daily treatment for schizophrenia, ... The active pharmaceutical ingredient in Seroquel is quetiapine, ... In-PharmaTechnologist.com

Quetiapine efficacy equal to risperidone.  -  Jan 9, 2006
A new study published in the European Archives of Psychiatry and Clinical Neuroscience (January 4) demonstrates that quetiapine (AstraZeneca's Seroquel) and ... Pay-Per-View - Pharma Marketletter - Factiva, from Dow Jones

CATIE Phase I Helps Clinicians Tailor Schizophrenia Treatment  -  Dec 1, 2005
The average time to discontinuation, according to Lilly's press statement, was 9.2 months for olanzapine, 4.6 months for quetiapine, 4.8 months for ... Psychiatric Times

Data further examines SeroquelÆ (quetiapine fumarate) treatment for …  -  May 20, 2005
WILMINGTON, Del, Tuesday May 24 2005 ñ AstraZeneca (NYSE: AZN) today announced additional findings at the annual meeting of the American Psychiatric ... PsychCentral.com

Quetiapine okayed for treatment of bipolar depression.(Mental...  -  Nov 15, 2006
Quetiapine okayed for treatment of bipolar depression.(Mental Health)(Brief article) ... find Family Practice News articles. Quetiapine has been approved ... Pay-Per-View - Family Practice News - HighBeam Research

Quetiapine may help manage depression in bipolar adolescents.(care …  -  Apr 1, 2006
Quetiapine may help manage depression in bipolar adolescents.(care and treatment) ... find Clinical Psychiatry News articles. TORONTO -- Quetiapine appears ... Pay-Per-View - Clinical Psychiatry News - HighBeam Research

Bipolar Disorder; Quetiapine effective as long-term adjunctive...  -  Aug 30, 2005
2005 AUG 30 - (NewsRx.com) -- Quetiapine is safe and effective as a long-term adjunctive treatment for bipolar mania. In a recent study from South Korea, ... Pay-Per-View - Life Science Weekly - Factiva, from Dow Jones

New Data Offers Hope to Patients With Bipolar Disorder and …  -  Sep 19, 2006
...significantly greater with quetiapine 300 and 600 mg/d than with placebo (week 1 ... Two placebo-controlled trials of quetiapine monotherapy in 403 patients ... Newswit.com

… Comparative Analysis of INVEGA(TM) and Quetiapine in Schizophrenia...  -  Oct 8, 2007
Topline Findings from Comparative Analysis of INVEGA(TM) and Quetiapine in Schizophrenia to be Postered at the 20th Annual US Psychiatric and Mental Health ... Pay-Per-View - PR Newswire - HighBeam Research

Article: Quetiapine has efficacy for adolescent mania.(Disease/Disorde...  -  May 1, 2006
Quetiapine has efficacy for adolescent mania.(Disease/Disorder overview)(Brief article) ... find Internal Medicine News articles. Quetiapine was at least as ... Pay-Per-View - Internal Medicine News - HighBeam Research

quetiapine AstraZeneca ceases development of granule formulation.(Brie...  -  Jul 18, 2005
...quetiapine, quetiapine fumarate, ZD 5077, Zeneca 204636, ICI 204636, FK 949, SEROQUEL, N5A, Antipsychotics, AstraZeneca. Pay-Per-View - R & D Focus Drug News - Factiva, from Dow Jones

Quetiapine for bipolar disorder  -  Jul 9, 2005
Over 500 patients with bipolar disorder who were experiencing a major depressive episode were randomised to receive quetiapine at a daily dose of 300mg or ... Pay-Per-View - Chemist & Druggist - Factiva, from Dow Jones

quetiapine AstraZeneca provides development update.(Brief Article)  -  Sep 5, 2005
AstraZeneca reported on 28 July 2005 that phase III trials of quetiapine (SEROQUEL) are under way in the USA in patients with bipolar depression. ... Pay-Per-View - R & D Focus Drug News - Factiva, from Dow Jones

Brand Names/Synonyms:
Quetiapine is also known by the following brand names and/or synonymsCHEMBANK1802; Quetiapin Hemifumarate; Quetiapine; Quetiapine Fumarate; Quetiapine Hemifumarate; Seroquel; ZD5077

Drug Category:
Quetiapine is categorized under the following by the FDA: Antipsychotics; ATC:N05AH04

Dosage Forms:
TABLET

Absorption:
Rapidly and well absorbed.

Interactions:
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Chemical IUPAC Name:
Not Available





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