Ramipril

This page contains recent news articles, when available, and an overview of Ramipril but does not offer medical advice. You should contact your physician with regard to any health issues or concerns.


Overview:

Ramipril
(when available)

Pharmacology and use:
Ramipril is an angiotensin-converting enzyme (ACE) inhibitor similar to benazepril, fosinopril, and quinapril. An inactive prodrug, ramipril is converted to ramiprilat in the liver and is used to treat hypertension and heart failure, to reduce proteinuria and renal disease in patients with nephropathies, and to prevent stroke, myocardial infarction, and cardiac death in high-risk patients. Indicated for diuretics and digitalis in congestive heart failure as adjunctive therapy; prophylaxis in post MI.

Mechanism Of Action:
Ramiprilat, the active metabolite, competes with angiotensin I for binding at the angiotensin-converting enzyme, blocking the conversion of angiotensin I to angiotensin II. As angiotensin II is a vasoconstrictor and a negative-feedback mediator for renin activity, lower concentrations result in a decrease in blood pressure and an increase in plasma renin. Ramiprilat may also act on kininase II, an enzyme identical to ACE that degrades the vasodilator bradykinin.

News Articles on Ramipril

Sanofi-Aventis to buy Chattem for about $1.9B  -  ‎Dec 22, 2009‎
Sanofi-Aventis makes diabetes treatment Lantus (insulin glargine), a long-acting basal insulin analogue, and Tritace (ramipril) an ACE inhibitor indicated ... NephrOnline

Prescription drugs stolen from car in Hagley  -  ‎Dec 29, 2009‎
...pen called Novorapid and a grey pen called Lantus Solostar) and two packets of tablets - Ramipril for blood pressure and Simvastatin for cholesterol. ... Stourbridge News

AT HIGH RISK FOR HEART ATTACK  -  ‎Jan 4, 2010‎
Concomitant use of telmisartan and ramipril is not recommended. The most common adverse events occurring with MICARDIS Tablets at a rate of ≥1% and greater ... North American Press Syndicate

50 per cent Australians suffer from obesity, high BP  -  ‎Dec 11, 2009‎
Drugs for blood pressure alone accounted for 20 per cent of all drugs dispensed, with four off patent blood pressure-lowering medications like ramipril, ... TopNews United States

How to control high blood pressure  -  ‎Dec 17, 2009‎
The three main groups used as first-line treatment include ACE inhibitors (eg ramipril), calcium channel blockers (eg amlodipine) and a type of water tablet ... WalesOnline

Gift fürs Pharma-Geschäft  -  ‎Dec 10, 2009‎
Beispiel Ramipril: An einer Packung mit 20 Tabletten seines Blutdrucksenkers, dessen Patentschutz abgelaufen ist, verdient der französische Hersteller ... Financial Times Deutschland

The Case for Dual Renin-Angiotensin System Inhibition  -  ‎Nov 9, 2009‎
Ku et al 1 cite the findings of the Renal Outcomes With Telmisartan, Ramipril, or Both, in People at High Vascular Risk (ONTARGET) trial 2 in arguing ... Archives of Internal Medicine

Clinical Trial: No  -  ‎Nov 6, 2009‎
Methods: The authors analyzed data from the Ongoing Telmisartan Alone and in Combination With Ramipril Global End Point Trial (ONTARGET), as well as the ... Cardiosource

Strict Blood Pressure Control and Progression of Renal Failure in Children  -  ‎Nov 3, 2009‎
All participants were treated with high-dose ramipril (6 mg/m 2 ). Participants were then randomized to the conventional BP target of 50-90th percentile for ... Cardiosource

Strict BP Control Helps Save Kids' Renal Function  -  ‎Oct 21, 2009‎
Among patients treated with an intensified regimen that included a fixed high dose of ramipril, 29.9% reached the primary endpoint, a 50% reduction in ... MedPage Today

FDA approves additional use for hypertension drug  -  ‎Oct 20, 2009‎
55 years and older who can't take drugs belonging to the class known as ACE inhibitors, which includes such generic drugs as ramipril and lisinopril. ... Drug Store News (blog)

ACG: ACE Inhibitor Use Linked to Liver Toxicity  -  ‎Oct 26, 2009‎
...which showed that 26 of the cases resulted from captopril use, nine involved enalapril, and three each involved lisinopril, ramipril, and fosinopril. ... MedPage Today

FDA Approves New Use for Micardis(R) in Cardiovascular Risk Reduction and ...  -  ‎Oct 19, 2009‎
Concomitant use of telmisartan and ramipril is not recommended. The most common adverse events occurring with MICARDIS Tablets at a rate of greater than or ... Reuters

ALLHAT Findings Revisited in the Context of Subsequent Analyses, Other Trials ...  -  ‎Oct 26, 2009‎
The Ongoing Telmisartan Alone and in Combination with Ramipril Global Endpoint Trial (ONTARGET) report has raised further doubts of renoprotection with ... Archives of Internal Medicine

King Pharmaceuticals Reports Strong Third Quarter 2009 Financial Results  -  ‎Nov 5, 2009‎
...of generic substitutes for ALTACE ® (ramipril) beginning in December 2007, offset by the addition of revenues from sales of FLECTOR ® PATCH and EMBEDA™. ... WELT ONLINE

Dr Reddy's seeks US marketing rights for `Lipitor' generic  -  ‎Nov 7, 2009‎
Risperidone (Risperdal - Janssen), Ramipril (Altace - King), Venlafaxine (Effexor -Wyeth), Lamotrigine (Lamictal - Glaxo Smith Kline), and Levetiracetam ... domain-B

FDA Approves MICARDIS® (Telmisartan) As the First Treatment in its Class to ...  -  ‎Oct 19, 2009‎
The results also demonstrated that MICARDIS® is better tolerated than the previous gold standard ramipril and associated with higher treatment adherence.1-2 ... Reuters

AstraZeneca takes Lupin to NJ court over Nexium  -  ‎Nov 9, 2009‎
First go ahead, challenge and then enter into a settlement, Effexor XR, Desloratadine, Ramipril and bunch of other filings. All of these have probably been ... Moneycontrol.com

CHMP Issues Positive Opinion for MICARDIS® (telmisartan) as the First ...  -  ‎Oct 23, 2009‎
...that MICARDIS® is better tolerated than the previous gold standard ramipril and is associated with higher treatment adherence.1-2 Professor Klaus Dugi, ... Reuters

ACE inhibitors of benefit in ischemic heart disease patients with preserved LV ...  -  ‎Oct 20, 2009‎
...from ONTARGET: the ACE inhibitor/ARB (ramipril/telmisartan) combination was associated with more adverse events, specifically hypotension and syncope, ... TheHeart.Org

Intensified Blood Pressure Control May Improve Renal Function in Children With CKD  -  ‎Oct 27, 2009‎
They underwent a 6-month run-in period and were then treated with ramipril, 6 mg per square meter of body surface area per day. ... Medscape

PRESS RELEASE: Novartis Delivers Strong New -4-  -  ‎Oct 21, 2009‎
...for more than 24 hours, and superiority in clinical trials over ramipril, a leading ACE inhibitor (an older class of high blood pressure medicines). ... Capital.gr (press release)

* The ONTARGET Trial results reviewed by the CHMP showed that Micardis® may ...  -  ‎Oct 23, 2009‎
Telmisartan, ramipril, or both in patients at high risk for vascular events. N Eng J Med.2008;358:1547-1559. 2 The TRANSCEND Investigators 2008. ... PipelineReview.com (press release)

Telmisartan – evidenzbasierte Schutzwirkung für Risikopatienten  -  ‎Oct 22, 2009‎
Evidenzbasiert in Endpunktstudien dokumentiert sind sie nach Asmar bei den ACE-Hemmern nur für Ramipril und bei den AT1-Blockern nur für Telmisartan. ... IBTimes Deutschland

미카르디스 유럽서ë?„ í?¬ì†Œì‹?  -  ‎Oct 25, 2009‎
...ì?´ë²ˆ 시험ì?€ ONTARGET ìž„ìƒ?시험 ê²°ê³¼ì—? 근거한 것으로 ì?´ 시험ì?€ 표준 치료(gold standard)로 여겨졌ë?˜ ë?¼ë¯¸í”„릴(ramipril)ì—? 비해 내약성ì?´ ë?” 좋고 치료 순ì?‘ë?„ë?„ ë?” ... 메디칼트리뷴

'미카르디스' 심혈관계 치료제 승ì?¸  -  ‎Oct 22, 2009‎
ONTARGET 결과는 ë˜?한 미카르디스가 ì?´ì „까지 표준치료(gold standard)로 여겨졌ë?˜ ë?¼ë¯¸í”„릴(ramipril) 보다 내약성ì?´ 우수하고, 치료 순ì?‘ë?„ë?„ ë?” 높ì?Œì?„ ìž…ì¦?했다. ... 디지틀보사

EXFORGEì?˜ 효능 효과  -  ‎Nov 2, 2009‎
2000년대 ë³´ê³ ë?œ HOPE 연구ì—?ì„  위약 êµ°ì—? 비해 ACE억제제ì?¸ ramiprilì?„ 투여한 êµ°ì—?서 심혈관계 사ë§?, 심근경색, 뇌졸중ì?„ 줄ì?´ëŠ” ë³´ê³ ê°€ 있었으며 ONTARGET 연구 ... 코리아헬스로그

“Bu ölümcül bir adımdır!â€?  -  ‎Oct 20, 2009‎
Yeni listeden örnek olarak 'ramipril' ve 'silazapin' etken maddelerinin eÅŸdeÄŸer olmadığı halde, eÅŸdeÄŸer kabul edildiÄŸi belirtildi. ... Hürriyet

Strengere bloeddrukverlaging spaart nierfunctie kinderen  -  ‎Oct 26, 2009‎
Zij kregen ramipril, allemaal in eenzelfde dosis in verhouding tot hun gewicht. Bij een deel van de kinderen werd de streefwaarde van de bloeddruk gesteld ... NierNieuws.nl

고혈압 'ARB+CCB' 복합제…미국 FDA 승ì?¸  -  ‎Oct 21, 2009‎
ONTARGET 결과는 ë˜?한 미카르디스가 ì?´ì „까지 표준치료(gold standard)로 여겨졌ë?˜ ë?¼ë¯¸í”„릴(ramipril) 보다 내약성ì?´ 우수하고, 치료 순ì?‘ë?„ë?„ ë?” 높ì?Œì?„ ìž…ì¦?했다. ... 메디컬헤럴드

ベーリンガーインゲルãƒ?イムã€?アンジオテンシンIIå?—容体拮抗薬「ミカルディスã€?ã?§ ...  -  ‎Oct 20, 2009‎
...Telï½?isï½?ï½’ï½”ï½?n,rï½?ï½?iï½?ril,ï½?ï½’ bï½?th in ï½?ï½?tients ï½?ï½” high risk fï½?ï½’ ï½–ï½?sculï½?ï½’ events. ... 日本経済新聞 (プレスリリース)

미카르디스, ACE 억제제를 복용할 수 없는 환ìž? 치료제 FDA 승ì?¸  -  ‎Oct 21, 2009‎
ONTARGET 결과는 ë˜?한 미카르디스®가 ì?´ì „까지 표준치료(gold standard)로 여겨졌ë?˜ ë?¼ë¯¸í”„릴(ramipril) 보다 내약성ì?´ 우수하고, 치료 순ì?‘ë?„ë?„ ë?” 높ì?Œì?„ ìž…ì¦?했다. ... 헬스코리아뉴스

DJ HUGIN NEWS/Novartis verzeichnet in den ersten -6-  -  ‎Oct 21, 2009‎
Überlegenheit von Rasilez/Tekturna in klinischen Studien gegenüber Ramipril, einem führenden ACE-Hemmer (eine ältere Kategorie von Blutdrucksenkern). ... unternehmer.de

India's Lupin gets final FDA approval for Ramipril hypertension drug  -  Jun 11, 2008
MUMBAI (Thomson Financial) - India's Lupin Ltd. said the US Food and Drug Administration has granted final approval for the company's abbreviated new drug ... Forbes

Novartis says renin inhibitor Rasilez superior in tests over Ramipril  -  Jun 13, 2006
BASEL (AFX) - Novartis AG said new clinical data shows that its oral direct renin inhibitor Rasilez reduces systolic blood pressure better than the standard ... Forbes

THE NATION; Drug May Delay or Even Prevent Type 2 Diabetes  -  Sep 16, 2006
Earlier studies on treating diabetes had suggested that rosiglitazone and a second drug, ramipril, might also halt progression to diabetes. ... Pay-Per-View - Los Angeles Times - ProQuest Archiver

Blood pressure drug Micardis cuts heart risk: study  -  Mar 31, 2008
Ramipril is an angiotensin converting enzyme, or ACE, inhibitor. ... Telmisartan and ramipril alone worked equally well to reduce cardiovascular death, ... Reuters

A Multicenter, 14-Week Study of Telmisartan and Ramipril in Patients...  -  Mar 22, 2005
Correspondence: Dr. Yves Lacourcière, Director, Hypertension Research Unit, CHUL, Centre Hospitalier Universitaire de Quebec, 2705 boul Laurier S-135, ... Nature.com

Telmisartan (MICARDIS(R)) as Effective as Ramipril  -  Oct 24, 2008
New results from the landmark ONTARGET(R) Trial show that, in Asian patients at high risk of cardiovascular disease (CVD), telmisartan (MICARDIS(R)) 80mg is ... ANTARA

… of single versus twice daily dosing of ramipril by ambulatory...  -  Apr 9, 2006
This paper was dealt with by a Guest Editor, Associate Professor Bernard Cheung from the University of Hong Kong, and editorial decisions were independent ... Nature.com

King Pharma Seeks Rehearing  -  Sep 12, 2007
Earlier this year King announced positive results from a phase III clinical trial evaluating its Altace (ramipril) diuretic combination product, ... TheStreet.com - TheStreet.com (subscription)

New blood-pressure drug has fewer side effects: study  -  Mar 31, 2008
Telmisartan rivals the commonly used ramipril in keeping heart attacks at ... They received either 10 mg a day of ramipril, 18 mg a day of telmisartan or a ... CBC.ca

Differential Effects of Ramipril on Ambulatory Blood Pressure in...  -  Nov 15, 2006
Correspondence: Dr. Ronald M. Krauss, Atherosclerosis Research, Children's Hospital Oakland Research Institute, 5700 Martin Luther King, Jr. Way, Oakland, ... Nature.com

… Effects on Blood Pressure Compared With Ramipril: Presented at ACC  -  Mar 27, 2007
Dose titration to aliskiren 300 mg/ramipril 10 mg and subsequent HCTZ addition ... More patients in the ramipril group required addition of HCTZ (49.5% vs. ... DG News

India's Cipla gets FDA nod for ramipril capsules  -  Aug 12, 2008
MUMBAI, Aug 12 (Reuters) - Indian drugmaker Cipla Ltd (CIPL.BO) has received approval from the US Food and Drug Administration to market ramipril capsules, ... Reuters

King Pharma says petition for rehearing on Altace ruling denied  -  Dec 3, 2007
The ruling would allow the sale of cheaper generic versions of the medicine known chemically as ramipril. (Reporting by Aniruddha Basu in Bangalore; ... Reuters

… -Effectiveness in Italy of Preventive Treatment With Ramipril in...  -  Jul 13, 2005
The cohorts used were 1000 subjects on ramipril, and 1000 subjects on placebo ... Conclusions: On the basis of these results, the use of ramipril is likely ... RedOrbit

Novartis - Tekturna works better in older patients  -  Nov 11, 2008
VX) Tekturna reduced blood pressure in patients aged 65 and over by significantly more than the older drug ramipril, the Swiss drugmaker said on Tuesday. ... Reuters

Ramipril Improves Walking Ability in Patients with Peripheral...  -  May 2, 2006
Summaries for Patients are a service provided by Annals to help patients better understand the complicated and often mystifying language of modern medicine. ... Annals of Internal Medicine

Dip in DRL net profit  -  May 7, 2005
Citing VAT as the reason behind the fall in domestic markets, CEO GV Prasad said: ''Fluoxetine, Tizanidine in the US and Ramipril in Europe witnessed ... Indian Express

RAMIPRIL (Oral route) - ra-MI-pril.(Drug overview)  -  May 1, 2007
When used in pregnancy during the second and third trimesters, ACE inhibitors can cause injury and even death to the developing fetus. ... Free with registration - USP DI-Volume II, Advice for the... - AccessMyLibrary.com

… May Be an Effective and Safe Alternative to Ramipril in Patients...  -  Apr 7, 2008
After 2 weeks, the dose of ramipril was increased to 10 mg per day. ... The proportion of patients receiving the full dose of ramipril at 2 years was 81.7% ... DG News

Ramipril of Limited Benefit in Preventing Diabetes, But………..  -  Oct 17, 2006
However, ramipril may improve glucose metabolism by promoting regression to normal blood sugar levels or "normoglycemia," according to investigators ... Diabetes In Control

Ramipril Reduces C-reactive Protein and Endothelial Function:...  -  Nov 4, 2005
By Danny Kucharsky. MONTREAL, CANADA -- November 4, 2005 -- Ramipril reduces the levels of high sensitivity C-reactive protein (CRP) in a cohort of healthy ... DG News

… Pharmaceuticals Reports DREAM Data on Ramipril; Results Presented...  -  Sep 15, 2006
BRISTOL, Tenn. -- King Pharmaceuticals, Inc. (NYSE:KG) today reported that the results of the Diabetes Reduction Assessment with Ramipril and Rosiglitazone ... $4.95 - Business Wire - ECNext

Dr Reddy's launches atorvastatin and ramipril combo in India.  -  May 30, 2008
Dr Reddy's Laboratories Ltd. has launched Atocor-R (Atorvastatin + Ramipril) in India. It is the first such combination to be approved by DCGI and has ... pharmabiz.com

Telmisartan Superior to Ramipril in Preventing Morning Blood Pressure...  -  May 19, 2005
By Ed Susman. SAN FRANCISCO, CA -- May 19, 2005 -- The sometimes problematic early morning blood pressure surge is better prevented by the angiotensin ... DG News

A Mid-Summer's Night DREAM: Diabetes Prevention (Part 2- Ramipril …  -  Sep 19, 2006
The Dream Study also found that the ACE-inhibitor Altace (ramipril) does not prevent type 2 diabetes in patients with impaired glucose metabolism. ... Diabetes In Control

… Alone and in Combination With Ramipril Global Endpoint Trial ( …  -  May 19, 2008
Description: The goal of this trial was to determine whether the angiotensin-receptor blocker (ARB) telmisartan was noninferior to the ... Medscape

Lupin wins Ramipril product patent challenge  -  Oct 15, 2007
Lupin has announced that the Court of Appeals for the Federal Circuit has reversed a district court decision on Ramipril in its favor, finding the Aventis ... Express Pharma

Rosiglitazone, Not Ramipril, Prevents Progression to Diabetes in...  -  Dec 14, 2006
Among patients at risk for progression to diabetes, metformin and acarbose therapy each modestly reduce the likelihood of progression; dietary modifications ... Medscape

King Pharmaceuticals Reports Publication of HOPE-TOO Clinical Trial …  -  Sep 6, 2005
The currently ongoing Diabetes REduction Assessment with ramipril and rosiglitazone ... The HOPE-TOO results confirm the sustained value of ramipril." ... RedOrbit

… ramipril's ability to prevent diabetes.(Diabetes Assessment with...  -  Oct 14, 2006
The Diabetes Assessment with Ramipril and Rosiglitazone Medication study ... The incidences of diabetes and death in the ramipril and placebo groups were ... Free with registration - Chemist & Druggist - AccessMyLibrary.com

Re-examining RAS-blocking treatment regimens for abrogating …  -  Sep 11, 2008
ONTARGET investigators (2008) Telmisartan, ramipril, or both in patients at high risk for vascular events. N Engl J Med 358: 1547–1559 | Article | PubMed ... Nature.com

Aliskiren as Monotherapy and in Combination With Other Agents  -  Jun 12, 2007
Dose titration (to aliskiren 300 mg/ramipril 10 mg) and subsequent addition of a diuretic, HCTZ 12.5 mg, titrated to 25 mg if required, were permitted at ... Medscape

… of single versus twice daily dosing of ramipril by ambulatory...  -  Apr 9, 2006
This paper was dealt with by a Guest Editor, Associate Professor Bernard Cheung from the University of Hong Kong, and editorial decisions were independent ... Nature.com

… Nephropathy; Lercanidipine and ramipril reduce albumin excretion...  -  Mar 14, 2005
2005 MAR 14 - (NewsRx.com) -- Lercanidipine and ramipril reduce albumin excretion rate in hypertensive type 2 diabetic patients with microalbuminuria. ... Pay-Per-View - Health & Medicine Week - Factiva, from Dow Jones

Zydus Pharma gets USFDA nod for Ramipril capsules  -  Sep 4, 2008
US-based Zydus Pharmaceuticals, a subsidiary of Zydus Cadila, has received final approval from the US Food and Drug Administration (USFDA) to market ... Myiris.com

… Nephropathy; Lercanidipine and ramipril reduce albumin excretion...  -  Mar 18, 2005
2005 MAR 18 - (NewsRx.com) -- Lercanidipine and ramipril reduce albumin excretion rate in hypertensive type 2 diabetic patients with microalbuminuria. ... Pay-Per-View - Drug Week - Factiva, from Dow Jones

Triasyn - Felodipine/Ramipril - Medical Drug  -  Apr 12, 2007
Triasyn comes in two strengths, these are a 2.5mg/2.5mg tablet and a 5mg/5mg tablet. Your doctor will decide which strength to initiate you on depending on ... Virtual Medical Centre - The Virtual Medical Centre

Lupin announces District Court Ruling on Ramipril  -  Jul 19, 2006
Lupin Ltd has announced that the United State District Court for the Eastern District of Virginia has issued an opinion following the completion of a trial ... Equity Bulls

Pritor® And Kinzalmono® As Protective As Current Gold Standard …  -  Apr 5, 2008
The HOPE (2) trial, by which ramipril was established as the current gold standard ... 25 patients stopped their treatment in the ramipril arm because of ... Medical News Today - Medical News Today (press release)

Statins; Simvastatin alone or with ramipril had positive effects on …  -  Feb 8, 2005
..."Simvastatin alone or combined with ramipril significantly changed lipoproteins, ... "However, simvastatin combined with ramipril changed to greater but ... Pay-Per-View - Life Science Weekly - Factiva, from Dow Jones

Ramipril fails to reduce the incidence of new-onset diabetes or death.  -  Nov 1, 2006
Ramipril fails to reduce the incidence of new-onset diabetes or death. In a randomized, double-blind, placebo-controlled trial, the angiotensin-converting ... $9.94 - Formulary - Alacra Store

Companies Dispute Cobalt's Generic Altace Exclusivity  -  Oct 23, 2007
The companies entered into an agreement under which Cobalt admitted that making, using, offering to sell, importing or selling ramipril capsules would ... FDA news - FDA news (subscription)

Statins; Simvastatin alone or with ramipril had positive effects on …  -  Feb 13, 2005
..."Simvastatin alone or combined with ramipril significantly changed lipoproteins, ... "However, simvastatin combined with ramipril changed to greater but ... Pay-Per-View - Heart Disease Weekly - Factiva, from Dow Jones

Colesterol high or what?  -  Nov 8, 2008
I'm sure that's a bit high, but as I'm taking azathioprine as well as ramipril, does that have an effect on the results? ... Daily Mail

Poor Results for King Pharmaceuticals' Ramipril Drug  -  Sep 18, 2006
The drug was manufactured to prevent the development of type 2 diabetes in non-diabetic patients. Patients taking ramipril showed no difference to the ... RedOrbit

Renal Outcomes With Telmisartan, Ramipril, or Both, in People at High...  -  Sep 15, 2008
Author(s): Mann JF, Schmieder RE, McQueen M, et al., on behalf of the ONTARGET Investigators. Study Question: What are the renal effects of ramipril, ... Cardiosource

Generic name: Ramipril  -  Dec 1, 2005
Altace is used in the treatment of high blood pressure. It is effective when used alone or in combination with other high blood pressure medications, ... Free with registration - PDR Family Guide to Prescription Drugs - AccessMyLibrary.com

Single Drug May Suffice to Lower Albumin Excretion Rate  -  Oct 16, 2007
Baseline mean seated BP was 163/90 and 164/89 mm Hg in the ramipril plus irbesartan group and ramipril plus placebo groups, respectively. ... Renal and Urology News

Brief Communication: Ramipril Markedly Improves Walking Ability in …  -  May 2, 2006
Background: Peripheral arterial disease (PAD) affects up to 12% of adults older than 50 years of age. Conventional therapies have only modest effects in ... Annals of Internal Medicine

Roxane Laboratories, Inc. Announces the Launch of Ramipril Capsules  -  Jun 18, 2008
COLUMBUS, Ohio, June 18 /PRNewswire/ -- Roxane Laboratories, Inc. announced today the approval of its Abbreviated New Drug Application (ANDA) for Ramipril ... RedOrbit

Ramipril Combined With Candesartan Plus ACE Inhibitor Shows …  -  Nov 17, 2006
By Ed Susman. CHICAGO, IL -- November 17, 2006 -- Combining the angiotensin converting enzyme inhibitor ramipril with the angiotensin receptor blocker ... DG News

… With Warfarin, Digoxin or Ramipril Considered Safe: Presented at...  -  Sep 21, 2006
Eighteen of 22 healthy adults completed the vildagliptin/ramipril ... Coadministration of ramipril 5 mg daily and vildagliptin 100 mg daily did not result ... DG News

More data with aliskiren  -  Jun 15, 2006
Patients were randomized to one of three treatment strategies?ramipril alone, ... Ramipril was started at a dose of 5 mg once daily, and aliskiren was ... Medscape

Ramipril Lowers Diabetes Risk Among African Americans With …  -  Apr 25, 2006
Compared with metoprolol and amlodipine, ramipril treatment is associated with a lower risk of developing type 2 diabetes in African American patients with ... Diabetes In Control

Safety, efficacy shown for metoprolol, ramipril.(Clinical Rounds)  -  Nov 1, 2006
NEW YORK -- Two different classes of antihypertensive drugs were safe and effective for use in children based on results from two separate studies reported ... Free with registration - Pediatric News - AccessMyLibrary.com

Press Release: Lupin Launches Ramipril Capsules. - PR Newswire | …  -  Jun 11, 2008
Lupin Launches Ramipril Capsules. from PR Newswire. Highbeam Research – FREE Trial. Pay-Per-View - PR Newswire - HighBeam Research

Pharmaceutical Research; Two ramipril formulations were compared for ...  -  Mar 28, 2006
Plasma ramipril and ramiprilat concentrations were analyzed by liquid ... From the ramipril and ramiprilat plasma concentration vs. time curves, ... Pay-Per-View - Life Science Weekly - Factiva, from Dow Jones

Ramace - Ramipril - Medical Drug  -  Apr 7, 2006
Ramipril is used for the treatment of mild to moderate high blood pressure. It is also used to reduce the risks of heart attacks, strokes and death in ... Virtual Medical Centre - The Virtual Medical Centre

Diabetes Therapy; Ramipril was linked to lower diabetes mellitus risk...  -  Jun 7, 2006
2006 JUN 7 - (NewsRx.com) -- Ramipril treatment was linked to a lower risk of diabetes mellitus in African Americans with hypertensive kidney disease. ... Pay-Per-View - Life Science Weekly - Factiva, from Dow Jones

Cipla gets USFDA nod for Ramipril capsules  -  Aug 8, 2008
Drug maker, Cipla has received final approval from the US Food and Drug Administration (USFDA) to market Ramipril capsules, in the strengths of 1.25 mg, ... Myiris.com

Aliskiren bests ramipril for hypertension in diabetics.(Cardiovascular...  -  Aug 15, 2006
Aliskiren bests ramipril for hypertension in diabetics.(Cardiovascular Medicine) ... find Family Practice News articles. Madrid -- Aliskiren, the novel ... Pay-Per-View - Family Practice News - HighBeam Research

… , Inc. Announces the Launch of Ramipril Capsules. - PR Newswire | …  -  Jun 18, 2008
Roxane Laboratories, Inc. Announces the Launch of Ramipril Capsules. from PR Newswire. Highbeam Research – FREE Trial. Pay-Per-View - PR Newswire - HighBeam Research

United States Federal Circuit Court of Appeals Reports - AVENTIS …  -  Sep 11, 2007
This is a patent infringement action concerning the pharmaceutical compound ramipril, which is marketed by King Pharmaceuticals, Inc. ("King") as a blood ... Pay-Per-View - United States Federal Circuit Court of... - Loislaw

Angiotensin-Converting Enzyme Inhibitors after Acute Myocardial …  -  Jan 4, 2005
All of the 95% CIs for the risk reduction seen with ramipril versus other ... The results show that the lower mortality rates in the ramipril group are ... Annals of Internal Medicine

Press Release: New Data On Renin Inhibitor SPP100 (Rasilez) …  -  Jun 13, 2006
Ramipril also is indicated in cardiovascular risk reduction. Ramipril is the ethyl ester of a non-sulfhydryl ACE inhibitor ... ... Pay-Per-View - PR Newswire - HighBeam Research

Article: Sandoz launches ramipril.(RX: RETAIL PHARMACY: Generic …  -  Jul 14, 2008
Sandoz launches ramipril.(RX: RETAIL PHARMACY: Generic Drugs)(Brief article) ... find Chain Drug Review articles. Sandoz Inc. has introduced ramipril, ... Pay-Per-View - Chain Drug Review - HighBeam Research

Dual inhibition with losartan and aliskiren: a promising therapeutic...  -  Aug 4, 2008
The combination of telmisartan and ramipril did not reduce the primary ... ONTARGET Investigators (2008) Telmisartan, ramipril, or both in patients at high ... Nature.com

Ramipril.  -  Jul 14, 2008
Lupin Pharmaceuticals is offering ramipril in 1.25-, 2.5-, 5-, and 10-mg capsules. Ramipril is an AB-rated equivalent of King Pharmaceutical's Altace and is ... $9.94 - Drug Topics - Alacra Store

… , Arrow, affiliates collaborate on new formulations of ramipril  -  Mar 14, 2006
Additionally, King has granted Cobalt Pharmaceuticals, Inc. a non-exclusive right to enter into the US ramipril market with a generic capsule formulation of ... Pay-Per-View - Life Science Weekly - Factiva, from Dow Jones

Sandoz launches ramipril.  -  Jul 14, 2008
Sandoz Inc. has introduced ramipril, a generic equivalent of King ... Sandoz is marketing ramipril capsules in 1.25-mg, 2.5-mg, 5-mg and 10-mg strengths. ... $9.94 - Chain Drug Review - Alacra Store

… Pressure Control Alone or in Combination With Valsartan or Ramipril...  -  Sep 13, 2007
Individually, aliskiren treatment provided a higher smoothness index of 0.81 over those seen for both valsartan and ramipril, at 0.72 and 0.74, respectively ... DG News

Safety, efficacy shown for metoprolol, ramipril.(Clinical Rounds) |...  -  Nov 1, 2006
Safety, efficacy shown for metoprolol, ramipril.(Clinical Rounds) ... find Pediatric News articles. NEW YORK -- Two different classes of antihypertensive ... Pay-Per-View - Pediatric News - HighBeam Research

Angiotensin receptor blocker reduces CV death risk  -  Sep 3, 2008
This latest study builds on earlier research from the ONTARGET trial which first showed that telmisartan was as effective as ramipril at reducing CVD risk ... Healthcare Republic - Healthcare Republic

Research and Markets: Analyze Dr Reddy's - the Second Largest …  -  Sep 30, 2006
The company's current best selling product is ramipril (Altace, ... Sales of ramipril amounted to Rs 1314.2 million in 2004, equal to 6.5% of total company ... businesswire.com

She looks like a man She's black People are uninformed bigots Women …  -  Mar 7, 2008
Ramipril is the active ingredient of Austell-Ramipril, Ramace, Ramipril Hexal, ... Ramipril is also one of multiple active ingredients found in Tri-Plen and ... Health24.com

ARBs versus ACEIs for High-Risk Vascular Patients  -  Jun 20, 2008
Telmisartan, Ramipril, or Both in Patients at High Risk for Vascular Events. ... The combination of telmisartan and ramipril offered no advantage over ... Medscape

DER SPIEGEL - SPIEGEL ONLINE - Nachrichten  -  Jan 24, 2005
Bis zum Verkauf hatte Hoechst mit Ramipril einen mäßigen Umsatz von rund 90 ... "Für uns war Ramipril", erinnert sich der damalige Chef der klinischen ... Spiegel Online

Aliskiren in Combination With ACE Inhibitor in Hypertensive Diabetics  -  Jul 13, 2006
The data also showed that in combination with ramipril, blood pressure ... After 4 weeks, dosages were force-titrated to aliskiren 300 mg, ramipril 10 mg, ... Medscape

Novel renin blocker effective in diabetics.(Cardiovascular Medicine)  -  Sep 1, 2006
This was significantly better than the 12.0 and 10.7 mm Hg reductions obtained with ramipril alone. In combination, the two drugs gave mean pressure ... $4.95 - Internal Medicine News - ECNext

The DREAM of ACE Inhibitors Replaced by the Reliability of Lifestyle ...  -  Jan 11, 2007
...[2] These results seemed particularly valid because ramipril improved the risk of developing diabetes even when different definitions of diabetes were ... Medscape

Does the angiotensin receptor blocker telmisartan prevent morbid …  -  May 21, 2008
The groups treated with either ramipril or telmisartan exhibited similar incidence ... The equivalence of the telmisartan and ramipril outcomes, therefore, ... Nature.com

Loislaw Federal District Court Opinions - AVENTIS PHARMA …  -  Jun 5, 2006
2: The active ingredient in Lupin's ramipril capsules is ramipril. ... 4: Lupin's ANDA protocol for manufacturing its ramipril requires an isomer ... Pay-Per-View - Loislaw Federal District Court Opinions - Loislaw

Pharmacokinetics and pharmacodynamics of the vasopeptidase inhibitor ...  -  Jul 6, 2005
Methods: We compared the effects of single oral doses of AVE7688 (5 and 25 mg) with those of 10 mg ramipril (R10), a selective ACE inhibitor, ... Nature.com

United States: No Explicit Teaching Necessary To Render Isolation Of ...  -  Feb 11, 2007
Aventis and its competitor Schering created new ACE inhibitors, including ramipril. Ramipril has five carbon atoms, each of which can be spatially oriented ... Mondaq News Alerts - Mondaq News Alerts (Registration)

Rationale and design of a study to evaluate management of proteinuria...  -  Mar 20, 2006
The trial compares ACE inhibitor therapy using ramipril with the ACE ... 20, 30 Should the combination of ramipril and irbesartan investigated in the ... Nature.com

Issues to consider in the pharmaceutical development of a cardiovascul...  -  May 14, 2008
Figure 2 High performance liquid chromatography (HPLC) results that show incompatibility between acetylsalicylic acid and ramipril. ... Nature.com

Blood pressure drug Telmisartan may help prevent stroke  -  Dec 13, 2007
Whether they used the drug alone or in combination with a different type of antihypertensive medication, ramipril, Weill Cornell Medical College researchers ... thecheers.org

HOPE-TOO: NATIONAL CANCER INSTITUTE COMMENT ON …  -  Mar 15, 2005
People in HOPE took the drug ramipril (a medicine to treat high blood pressure, ... At the end of the initial study, ramipril showed a clear benefit in ... Pay-Per-View - US Fed News - Factiva, from Dow Jones

Aliskiren Helps Elderly Patients Achieves Blood Pressure Control: …  -  Nov 14, 2008
Dr. Duprez and colleagues compared the effects of 12 weeks of monotherapy with aliskiren or ramipril on systolic blood pressure in 901 patients aged 65 ... DG News

Loislaw Federal District Court Opinions - AVENTIS PHARMA …  -  May 11, 2006
The '722 patent covers ramipril, a pharmaceutical compound. ... Ramipril is an "enzyme inhibitor" used to treat high blood pressure. ... Pay-Per-View - Loislaw Federal District Court Opinions - Loislaw

Jantungan? Lindungi dengan Telmisartan  -  Apr 9, 2008
TELMISARTAN, obat antihipertensi golongan angiotensin II Receptor Blocker (ARB) moderen, memberi perlindungan setara dengan Ramipril yang merupakan standar ... KOMPAS.com

Does the risk of developing diabetes in hypertensive kidney disease...  -  Jul 12, 2006
The incidence of diabetes per patient-year was 2.8% in the ramipril group, ... The adjusted RR of the composite endpoint with ramipril was also ... Nature.com

Science and Technology Results of global telmisartan study released  -  May 29, 2008
ONgoing Telmisartan Alone and in combination with Ramipril Global Endpoint Trial (ONTARGET) results was recently presented at the 57th Annual Scientific ... Philippine Star

Proteinuria lowering needs a multifactorial and individualized...  -  Aug 6, 2008
The regimen consisted of ramipril 5–10 mg/day, losartan 50–100 mg/day, verapamil 80–120 g/day and atorvastatin 10–20 mg/day in successive steps, ... Nature.com

Ontarget with high-risk cardiovascular patients  -  Apr 11, 2008
Ontarget results showed that telmisartan is just as good as ramipril but the former is ... Telmisartan and ramipril were originally used for the control of ... Inquirer.net

VUMC to research blood pressure medication's effect on Type 2 diabetes  -  Sep 2, 2008
The drug, Ramipril, belongs to a class of drugs known as angiotensin ... ACE inhibitors such as Ramipril work by reducing the body's production of ... Bizjournals.com

Press Release: King Pharmaceuticals Reports FDA Acceptance of Altace(...  -  Sep 22, 2005
Article: ALTACE(R) (Ramipril) Receives New Indication to Reduce ... ... Corporation (NYSE: AHP) announced today that ALTACE(R) (ramipril) received approval ... Pay-Per-View - PR Newswire - HighBeam Research

내피세í?¬ 기능 ë°? í•­ì—¼ì¦? 효과 ë³´ì—¬  -  May 23, 2005
...�번 연구 결과로 'simvastatin과 ramipril 병합요법'� ��� 단�요법보다 혈압과 고지혈�� 월등히 개선하면서, 내피세� 기능과 항염� 효과와 �불어 ��린 ... 브레��뉴스

é? é›¢ç³–尿病新藥露曙光  -  Oct 11, 2006
...在此一å‰?æ??下,一個å?–å??為「夢想ã€?(Diabetes reduction assessment with ramipril and rosiglitazone medication,DREAM)的大型臨床試驗,由加拿大麥克馬斯特大學 ... è?¯å?ˆæ–°è?žç¶²

Blood Pressure Drug Telmisartan Shows Powerful Activity Against...  -  Dec 17, 2007
Whether they used the drug alone or in combination with a different type of antihypertensive medication, ramipril, Weill Cornell Medical College researchers ... sciencedaily.com

Brand Names/Synonyms:
Ramipril is also known by the following brand names and/or synonymsAcovil; Altace; Carasel; Cardace; Delix; HOE 498; Hytren; Lostapres; Pramace; Quark; Ramace; Ramipril; Ramipril [Usan:Ban:Inn]; Ramiprilum [Latin]; Triatec; Tritace; Unipril; Vesdil

Drug Category:
Ramipril is categorized under the following by the FDA: Antihypertensive Agents; Angiotensin-converting Enzyme Inhibitors; ATC:C09AA05

Dosage Forms:
CAPSULE

Absorption:
The extent of absorption is at least 50-60% and is not significantly influenced by the presence of food in the GI tract, although the rate of absorption is reduced.

Interactions:
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Chemical IUPAC Name:
4-[2-(1-ethoxycarbonyl-3-phenyl-propyl)aminopropanoyl]-4-azabicyclo[3.3.0]octane-3-carboxylicacid





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