Rapamune

This page contains recent news articles, when available, and an overview of Rapamune but does not offer medical advice. You should contact your physician with regard to any health issues or concerns.


Overview:

Rapamune
(when available)

Pharmacology and use:
Sirolimus, a macrocyclic lactone produced by Streptomyces hygroscopicus, is an immunosuppressive agent indicated for the prophylaxis of organ rejection in patients receiving renal transplants. It is recommended that Sirolimus be used in a regimen with cyclosporine and corticosteroids. For the treatmnet of post operative pain

Mechanism Of Action:
Sirolimus inhibits T lymphocyte activation and proliferation that occurs in response to antigenic and cytokine (Interleukin IL-2, IL-4, and IL-15) stimulation by a mechanism that is distinct from that of other immunosuppressants. Sirolimus also inhibits antibody production. In cells, Sirolimus binds to the immunophilin, FK Binding Protein-12 (FKBP-12), to generate an immunosuppressive complex. The Sirolimus:FKBP-12 complex has no effect on calcineurin activity. This complex binds to and inhibits the activation of the mammalian Target Of Rapamycin (mTOR), a key regulatory kinase. This inhibition suppresses cytokine-driven T-cell proliferation, inhibiting the progression from the G1 to the S phase of the cell cycle.

News Articles on Sirolimus

Getting a Handle on Posttransplant Recurrence of HCC  -  ‎Dec 17, 2009‎
Two other promising agents that are unproven include the oral agent sorafenib (Nexavar), and the immunosuppressant sirolimus (Rapamune). ... Cancer Network

美国FDA更新部分抗排异è?¯è¯´æ˜Žä¹¦ 警示增加感染风险  -  ‎Jan 3, 2010‎
...需è¦?修改说明书的è?¯ç‰©æœ‰ï¼šRapamune(西罗莫å?¸ï¼‰ã€?Sandimmune(山地明,通用å??:环孢毒素A)和环孢毒素A仿制è?¯ã€?Neoral(环孢毒素Aè¡?生物)和Neoral仿制 ... 中国武汉

Rapamuneâ„¢ May Improve Responses to Gleevec® in Patients with Chordoma  -  ‎Nov 4, 2009‎
Researchers from Italy have reported that the addition of Rapamune® (sirolimus, rapamycin) to Gleevec® (imatinib) may improve disease control in patients ... Cancer Consultants

… New Dosing Recommendations For RAPAMUNE In High Immunologic …  -  Feb 3, 2007
Wyeth Pharmaceuticals, a division of Wyeth (NYSE: WYE), today announced that the US Food and Drug Administration (FDA) has approved new dosing ... Medical News Today - Medical News Today (press release)

Kidney Transplant Patients Who Took Rapamune(R) Achieved Superior …  -  May 23, 2005
SEATTLE, May 23 /PRNewswire-FirstCall/ -- Data from a large comparative study presented today at the American Transplant Congress showed that kidney ... RedOrbit

US FDA says Roche cancels heart transplant study  -  Feb 22, 2007
N under the brand name Rapamune. Immunosuppressant drugs aim to prevent organ rejection in people who have undergone transplant surgery. ... Reuters

… New Dosing Recommendations for RAPAMUNE in High Immunologic …  -  Feb 2, 2007
MADISON, NJ, Feb. 2 /PRNewswire-FirstCall/ -- Wyeth Pharmaceuticals, a division of Wyeth , today announced that the US Food and Drug Administration (FDA) ... Free with registration - PR Newswire - AccessMyLibrary.com

Health Canada Endorsed Important Safety Information on Rapamune ( …  -  Aug 25, 2006
In Canada, Rapamune® is authorized for the prevention of rejection only in patients who ... Such patients should continue to use Rapamune® as prescribed. ... DG News

Terminally Ill Kids Get `Chance' of Cancer Cure From Wyeth Drug  -  Jun 26, 2008
After the researchers found that Rapamune, also known as rapamycin, showed activity against the cells, Canadian regulators said the drug could be tested in ... Bloomberg

Medical News: General Nephrology  -  Mar 30, 2005
Consider using Rapamune (sirolimus) for immunosuppression in kidney transplant patients who develop Kaposi's sarcoma, as an alternative the standard ... MedPage Today

… dosing recommendations for Wyeth's Rapamune in high immunologic …  -  Mar 1, 2007
The company says Rapamune is the first and only kidney transplant drug with dosing recommendations specifically for the treatment of high immunologic risk ... Pay-Per-View - Transplant News - HighBeam Research

Is Wyeth's Torisel Better Than Wyeth's Rapamune?  -  Jun 6, 2007
Torisel is a prodrug of Rapamune, Wyeth's marketed immunosuppressant product. It is possible that cost concerns could lead to use of Rapamune as a "poor ... Gerson Lehrman Group

Study Suggests Drug-Eluting Stent Type And  -  May 16, 2006
Sirolimus, the active drug released for the stent, is marketed by Wyeth Pharmaceuticals, a division of Wyeth, under the name Rapamune®. ... Angioplasty.Org

Wyeth's Rapamune shown to reduce cancer risk in transplant recipients.  -  Nov 21, 2005
The Rapamune maintenance regimen trial, the largest randomized cyclosporine-withdrawal assessment undertaken to date, enrolled 430 patients from Europe, ... $4.95 - Pharma Marketletter - ECNext

Drug Takes Aim at Kidney Transplant Rejection  -  Nov 24, 2006
The study involved about 450 high-risk patients who were randomly assigned to receive sirolimus (Rapamune) and the standard anti-rejection drug tacrolimus ... Ivanhoe Broadcast News

… Transplant Patients Receiving Rapamune Without Cyclosporine Sho  -  Oct 19, 2005
Five Year Study Shows That Renal Transplant Patients Receiving Rapamune Without Cyclosporine Show Reduced Incidence of Non-Skin Cancer. from PR Newswire ... Pay-Per-View - PR Newswire Europe - HighBeam Research

New Rapamune dosing guide OKed by FDA.  -  Feb 12, 2007
New Jersey, USA-based Wyeth Pharmaceuticals says that the Food and Drug Administration has cleared new dosing recommendations for its immunosuppressant ... Free with registration - Pharma Marketletter - AccessMyLibrary.com

… : Kidney Transplant Patients Who Took Rapamune(R) Achieved Superior...  -  May 23, 2005
Kidney Transplant Patients Who Took Rapamune(R) Achieved Superior Graft Survival at 4 Years After Early Cyclosporine Withdrawal. from PR Newswire. Pay-Per-View - PR Newswire - HighBeam Research

Rapamune.(NEW DOSING)(Food and Drug Administration)(Brief article)  -  Mar 5, 2007
The FDA has approved new dosing recommendations for Rapamune (sirolimus), from Wyeth Pharmaceuticals, Madison, NJ, (973) 660-5000. ... Free with registration - Drug Topics - AccessMyLibrary.com

… New Dosing Recommendations for RAPAMUNE in High Immunologic …  -  Feb 2, 2007
FDA Approves New Dosing Recommendations for RAPAMUNE in High Immunologic Risk Renal Transplant Patients. from PR Newswire. Highbeam Research – FREE Trial. Pay-Per-View - PR Newswire - HighBeam Research

… device for Wyeth's Rapamune.(Abbott Laboratories manufacturing …  -  May 2, 2005
Drug Administration for an automated test for monitoring the therapeutic levels of Wyeth's anti-rejection drug, Rapamune (sirolimus), in whole blood. ... $4.95 - Pharma Marketletter - ECNext

Long Term Sirolimus Data Brings Hope for Kidney Transplant Patients.  -  Jan 31, 2005
4,5) Sirolimus (rapamycin, Rapamune(R)) is an immunosuppressive that is not nephrotoxic. The results clearly highlight sirolimus as a major advance in ... $4.95 - PR Newswire - ECNext

LifeCycle Pharma Announces New Product Candidate; Initiates Phase I …  -  Nov 29, 2007
Sirolimus is today marketed by Wyeth under the brand name Rapamune[R]. Rapamune is sold as an oral solution and tablet and coats the CYPHER coronary stent ... Free with registration - Business Wire - AccessMyLibrary.com

CsA withdrawal reduces cancer risk  -  Oct 20, 2005
...than patients who stay on a combination of cyclosporine plus sirolimus, five-year data from the Rapamune Maintenance Regimen (RMR) trial suggest [ 1 ]. ... Medscape

Rapamune.  -  Mar 5, 2007
The FDA has approved new dosing recommendations for Rapamune (sirolimus), from Wyeth Pharmaceuticals, Madison, N.J., (973) 660-5000. ... $9.94 - Drug Topics - Alacra Store

Rapamune.  -  Mar 1, 2007
FDA approved new dosing recommendations for sirolimus (Rapamune, Wyeth) for the treatment of renal transplant recipients at high immunologic risk. ... $9.94 - Formulary - Alacra Store

Early steroid withdrawal after renal transplantation.(Practice Issues...  -  Jan 1, 2006
Dose reduction or temporary cessation of Rapamune[R] or Cellcept[R] is ... Although steroids also contribute to increased serum lipids, Rapamune[R] can ... Free with registration - Nephrology Nursing Journal - AccessMyLibrary.com

Empresas.-Combinar 'Rapamune' (Wyeth) y micofenolato mejora la …  -  Jul 16, 2008
La asociación de micofenolato mofetilo y sirolimus, comercializado como 'Rapamune' por los laboratorios Wyeth, como terapia inmunosupresora de mantenimiento ... ecodiario

Infliximab Injection Side Effects from Consumer Reports Health.  -  Jan 4, 2007
Sandimmune), oral corticosteroids; 6-mercaptopurine (Purinethol); methotrexate (Rheumatrex), sirolimus (Rapamune), and tacrolimus (Prograf). ... consumerreports.org

La Rapamune, ou comment accepter son greffon  -  Jun 6, 2008
Des chercheurs de l'University of California de San Diego, dirigés par Robert Steiner, Professeur en Médecine et Directeur du "Transplant Nephrology", ... bulletins-electroniques.com

Press Release: Abbott and Axis-Shield Announce US 510(K) Clearance …  -  Apr 19, 2005
Wyeth's anti-rejection drug, Rapamune (sirolimus), in whole blood. The assay utilizes Abbott's IMx System, an automated ... in patients. ... Pay-Per-View - PR Newswire - HighBeam Research

Abbott and Axis-Shield Announce US 510(K) Clearance of an Automated …  -  Apr 19, 2005
RAPAMUNE is indicated for the prophylaxis of organ rejection in patients aged 13 ... It is recommended that RAPAMUNE be used initially in a regimen with ... $4.95 - PR Newswire - ECNext

Rapamune tablet  -  Apr 28, 2005
...* Dit geneesmiddel is alleen aan u voorgeschreven. Geef het dus niet door aan iemand anders. Het kan schadelijk voor hen zijn, zelfs als ze dezelfde ... Consumed

Enticing cells to 'eat' Huntington's  -  May 8, 2007
Although Rapamune is precribed over long periods to prevent rejection in transplant patients, there are side-effects associated with its use, including an ... DrugResearcher.com

Immune rejection drug shrinks rare tumors  -  Jan 9, 2008
N drug Rapamune dramatically reduces rare growths known as angiomyolipomas ... In four of the patients, Rapamune had to be stopped because of side effects, ... Reuters

Immune rejection drug shrinks rare tumors  -  Jan 10, 2008
BOSTON (Reuters) - The Wyeth drug Rapamune dramatically reduces rare growths ... In four of the patients, Rapamune had to be stopped because of side effects ... Reuters India

Ð’ СШÐ? разработаны новые рекомендации по применению препарата  -  Feb 7, 2007
FDA разработало новые рекомендации по режиму дозированиÑ? препарата RAPAMUNE® (Sirolimus) компании Wyeth Pharmaceuticals. Это ЛС предназначено длÑ? применениÑ? ... ФармацевтичеÑ?кий веÑ?тник

The prospect of quick riches has biotechs targeting the rarest of...  -  Oct 31, 2005
Rapamune was discovered in 1975, but only 20 years later did scientists figure out how it really worked:by hitting a cell receptor called mTOR, ... Pay-Per-View - Forbes - Factiva, from Dow Jones

Study finds low-dose Pharma drug best after transplant  -  Dec 19, 2007
It was highest -- 37 percent -- for low-dose Rapamune, known generically as sirolimus. After one year, the survival rate for the transplanted kidneys was ... Reuters

Press Release: International Cyclosporine-Withdrawal Trial Shows …  -  Nov 13, 2005
This analysis was part of the largest randomized cyclosporine-withdrawal study undertaken to date, the Rapamune Maintenance Regimen (RMR) Study. ... Pay-Per-View - PR Newswire Europe - HighBeam Research

Proteinuria following conversion from azathioprine to sirolimus in...  -  Aug 16, 2006
In a randomized, prospective, multicenter study called RESCUE (Recurrent cutanEous Squamous cell Carcinoma Under RapamunE) the efficacy and safety is ... Nature.com

Wyeth Reports Earnings Results for the 2005 Third Quarter and First...  -  Oct 21, 2005
RAPAMUNE(R), indicated for the prophylaxis of organ rejection in patients ... Prescription volume for Rapamune is currently growing at more than three times ... $4.95 - PR Newswire - ECNext

Philadelphia Inquirer, The : Clearing the Record  -  Nov 6, 2008
Rapamune is provided to Hawk through RapAssist, the Wyeth Pharmaceutical Assistance Foundation's specialized program for individuals who cannot afford the ... $2.95 - Philadelphia Inquirer - NewsBank

Philadelphia Inquirer, The (PA)  -  Nov 6, 2008
Rapamune is provided to Hawk through RapAssist, the Wyeth Pharmaceutical Assistance Foundation's specialized program for individuals who cannot afford the ... $2.95 - Philadelphia Inquirer - NewsBank

International Cyclosporine-Withdrawal Trial Shows Reduced Incidence...  -  Nov 13, 2005
This analysis was part of the largest randomized cyclosporine-withdrawal study undertaken to date, the Rapamune Maintenance Regimen (RMR) Study. ... Free with registration - PR Newswire - AccessMyLibrary.com

New Randomized Clinical Trial Results Show the Cypher(R) Sirolimus- …  -  Oct 23, 2006
Sirolimus, the active drug released for the stent, is marketed by Wyeth Pharmaceuticals, a division of Wyeth, under the name Rapamune(R). ... Free with registration - PR Newswire - AccessMyLibrary.com

SMART-Studie: Sirolimus 2-3 Wochen nach Nierentransplantation …  -  Oct 8, 2008
Sirolimus (Rapamune®) sollte initial in Kombination mit Ciclosporin Mikroemulsion und ... Rapamune® kann zusammen mit Kortikosteroiden im Rahmen einer ... journalmed.de

The place of sirolimus in kidney transplantation: Can we reduce …  -  Jul 26, 2006
Sehgal S. Rapamune (RAPA, rapamycin, sirolimus): mechanism of action ... MacDonald AS, for the Rapamune Study Group. A worldwide, phase III, randomized, ... Nature.com

Press Release: Competitive Technologies Licenses Homocysteine Assay …  -  Apr 28, 2005
Abbott's manufacturing partner Axis-Shield plc, based in Dundee, Scotland ... available at www.rapamune.com . Axis-Shield is a global manufacturer of in ... Pay-Per-View - PR Newswire - HighBeam Research

Press Release: International Cyclosporine-Withdrawal Trial Shows …  -  Nov 13, 2005
This analysis was part of the largest randomized cyclosporine-withdrawal study undertaken to date, the Rapamune Maintenance Regimen (RMR) Study. ... Pay-Per-View - PR Newswire - HighBeam Research

Cordis Corporation Announces Plans to Build State-of-the-Art …  -  Jul 25, 2006
Sirolimus, the active drug released for the stent, is marketed by Wyeth Pharmaceuticals, a division of Wyeth, under the name Rapamune(R). ... Free with registration - PR Newswire - AccessMyLibrary.com

Mission Improbable  -  Oct 21, 2005
Rapamune was discovered in 1975, but only 20 years later did scientists figure out how it really worked:by hitting a cell receptor called mTOR, ... RedOrbit

The REALITY Trial and Accompanying Editorial Appear in Prestigious …  -  Feb 21, 2006
Sirolimus, the active drug released for the stent, is marketed by Wyeth Pharmaceuticals, a division of Wyeth, under the name Rapamune(R). ... Free with registration - PR Newswire - AccessMyLibrary.com

Patient Enrollment Complete for Pivotal Trial of the NEVO(TM)...  -  Oct 27, 2008
Sirolimus, the active drug released for the stent, is marketed by Wyeth Pharmaceuticals, a division of Wyeth, under the name Rapamune(R). ... Genetic Engineering News - Genetic Engineering News (press release)

Internationale Studie zum Absetzen von Cyclosporin zeigt gesenkte …  -  Nov 13, 2005
Zum Fünfjahreszeitpunkt hatten 18 Patienten, die Rapamune plus Cyclosporin eingenommen hatten, einen Nicht-Haut-Krebs entwickelt im Vergleich zu acht ... presseportal.ch

DATA SUGGEST DRUG-ELUTING STENTS DIFFER IN RATE OF BLOOD …  -  Mar 7, 2005
Sirolimus, the active drug released for the stent, is marketed by Wyeth Pharmaceuticals, a division of Wyeth, under the name Rapamune(R). ... Free with registration - Asia Africa Intelligence Wire - AccessMyLibrary.com

Two-Year Data Suggest Different Rates Of Blood Clots And Heart...  -  Sep 6, 2006
Sirolimus, the active drug released for the stent, is marketed by Wyeth Pharmaceuticals, a division of Wyeth, under the name Rapamune(R). ... Medical News Today - Medical News Today (press release)

Transplant Medicine; Long term data on implant rejection is hopeful...  -  Feb 28, 2005
Sirolimus (rapamycin, Rapamune) is an immunosuppressive that is not nephrotoxic. The results clearly highlight sirolimus as a major advance in ... Pay-Per-View - Gastroenterology Week - Factiva, from Dow Jones

TCT2008 Concludes with Presentation of Positive Data for the CYPHER( …  -  Oct 30, 2008
Sirolimus, the active drug released for the stent, is marketed by Wyeth Pharmaceuticals, a division of Wyeth, under the name Rapamune(R). ... Genetic Engineering News - Genetic Engineering News (press release)

Transplant Medicine; Long term data on implant rejection is hopeful...  -  Mar 3, 2005
Sirolimus (rapamycin, Rapamune) is an immunosuppressive that is not nephrotoxic. The results clearly highlight sirolimus as a major advance in ... Pay-Per-View - Blood Weekly - Factiva, from Dow Jones

Transplant Medicine; Long term data on implant rejection is hopeful...  -  Mar 5, 2005
Sirolimus (rapamycin, Rapamune) is an immunosuppressive that is not nephrotoxic. The results clearly highlight sirolimus as a major advance in ... Pay-Per-View - Obesity, Fitness & Wellness Week - Factiva, from Dow Jones

Article: New dosing.(RXs)(Brief article) - Chain Drug Review |...  -  Apr 23, 2007
U.S. Food and Drug Administration (FDA) has approved new dosing recommendations for its immunosuppressant drug RAPAMUNE ... corticosteroids for the first ... Pay-Per-View - Chain Drug Review - HighBeam Research

Federal Register 2005 - 70 FR 43440 Summaries of Medical and Clinical  -  Jul 27, 2005
RAPAMUNE (sirolimus), and ZOFRAN (ondansetron). The summaries are being made available consistent with section 9 of the BPCA (Public Law 107-109). ... Pay-Per-View - Federal Register 2005 - Loislaw

Nanotechnology raises hopes for better drugs, diagnostics.  -  Apr 27, 2006
Other available nano drugs include Rapamune, developed by Wyeth Pharmaceuticals and approved in 1999 to prevent organ rejection in kidney transplant ... Free with registration - America's Intelligence Wire - AccessMyLibrary.com

People in the News  -  Aug 13, 2007
Orlando was most recently at Wyeth as the executive director of Rapamune global ... Rapamune is an immunosuppressant drug for the prevention of transplant ... $2.95 - Philadelphia Inquirer - NewsBank

Newly Published Data Suggest Better Outcomes With The CYPHER® …  -  Mar 12, 2006
Sirolimus, the active drug released for the stent, is marketed by Wyeth Pharmaceuticals, a division of Wyeth, under the name Rapamune®. ... Angioplasty.Org

TRANSPLANTS' CANCER THREAT ; EXPERTS SAY PATIENTS …  -  Dec 4, 2005
...patients who took cyclosporine, tacrolimus or similar drugs versus those treated with newer drugs called mTOR inhibitors, such as Rapamune or Rapamycin. ... Pay-Per-View - Richmond Times - Dispatch - ProQuest Archiver

CORDIS CORP TO DEVELOP GLOBAL CARDIAC, VASCULAR …  -  Apr 5, 2006
Sirolimus, the active drug released for the stent, is marketed by Wyeth Pharmaceuticals, a division of Wyeth, under the name Rapamune(R). ... Free with registration - AsiaPulse News - AccessMyLibrary.com

Press Release: Making Tailored Medical Treatment a Reality: New...  -  Aug 18, 2005
Article: FDA Approves New Indication for RAPAMUNE(R); - New Drug ... PR Newswire; April 11, 2003 ; 700+ words ...Wyeth Pharmaceuticals, the pharmaceutical ... Pay-Per-View - PR Newswire - HighBeam Research

Press Release: Long Term Sirolimus Data Brings Hope for Kidney …  -  Jan 31, 2005
Article: Kidney Transplant Patients Who Took Rapamune(R) ... PR Newswire; May 23, 2005 ; 700+ words ... ... Transplant Congress showed that kidney ... Pay-Per-View - PR Newswire - HighBeam Research

CYPHER STENT OVERLAP BETTER THAN BMS OVERLAP.  -  Sep 1, 2006
Sirolimus, the active drug released for the stent, is marketed by Wyeth Pharmaceuticals, a division of Wyeth, under the name Rapamune(R). ... Free with registration - Biotech Equipment Update - AccessMyLibrary.com

Media Release: Cordis Corporation.  -  Oct 21, 2005
Sirolimus, the active drug released for the stent, is marketed by Wyeth Pharmaceuticals, a division of Wyeth, under the name Rapamune(R). ... Free with registration - Asia Africa Intelligence Wire - AccessMyLibrary.com

Elan Announces the Johnson & Johnson Pharmaceutical Research …  -  Oct 29, 2007
Rapamune[R] is a registered trademark owned by Wyeth Pharmaceuticals. Emend[R] is a registered trademark owned by Merck & Co., Inc. Free with registration - Business Wire - AccessMyLibrary.com

New study results suggest better outcomes with the CYPHER® Stent than...  -  Oct 17, 2005
Sirolimus, the active drug released for the stent, is marketed by Wyeth Pharmaceuticals, a division of Wyeth, under the name Rapamune(r). ... eurekalert.org

CYPHER® Sirolimus-Eluting Coronary Stent to Be Featured in Late- …  -  Feb 28, 2005
Sirolimus, the active drug released for the stent, is marketed by Wyeth Pharmaceuticals, a division of Wyeth, under the name Rapamune®. ... i-newswire.com

Data Suggest Different Outcomes Between The CYPHER(R) Sirolimus- …  -  Oct 4, 2006
Sirolimus, the active drug released for the stent, is marketed by Wyeth Pharmaceuticals, a division of Wyeth, under the name Rapamune(R). ... Free with registration - PR Newswire - AccessMyLibrary.com

REALITY TRIAL DATA RELEASED.  -  Mar 9, 2005
Sirolimus, the active drug released for the stent, is marketed by Wyeth Pharmaceuticals, a division of Wyeth, under the name Rapamune(R). ... Free with registration - Asia Africa Intelligence Wire - AccessMyLibrary.com

LOS TRASPLANTADOS DE RIÑÓN TRATADOS CON SIROLIMUS …  -  May 24, 2005
Este estudio reporta una mayor supervivencia del trasplante renal en aquellos pacientes a los que se les mantuvo con una terapia de RAPAMUNE® (sirolimus) y ... acceso.com

NEJM, JAMA ARTICLES UNDERSCORE CLINICAL BENEFITS OF …  -  Aug 17, 2005
Sirolimus, the active drug released for the stent, is marketed by Wyeth Pharmaceuticals, a division of Wyeth, under the name Rapamune(R). ... $4.95 - AsiaPulse News - ECNext

New Long-Term Data Suggest Clinical Differences in Safety and...  -  Oct 22, 2007
Sirolimus, the active drug released for the stent, is marketed by Wyeth Pharmaceuticals, a division of Wyeth, under the name Rapamune[R]. ... Free with registration - Business Wire - AccessMyLibrary.com

CYPHER(R) Sirolimus-eluting Coronary Stent Had Similar Results to …  -  Mar 26, 2007
Sirolimus, the active drug released for the stent, is marketed by Wyeth Pharmaceuticals, a division of Wyeth, under the name Rapamune(R). ... Free with registration - PR Newswire - AccessMyLibrary.com

GROWING BODY OF EVIDENCE EXAMINES CYPHER CORONARY …  -  Feb 24, 2005
Sirolimus, the active drug released for the stent, is marketed by Wyeth Pharmaceuticals, a division of Wyeth, under the name Rapamune(R). ... Free with registration - AsiaPulse News - AccessMyLibrary.com

Roche extends NanoCrystal license  -  Jan 10, 2005
Rapamune was previously available only as an oral solution in bottles or sachets. The oral solution requires refrigeration storage, and must be mixed with ... In-PharmaTechnologist.com

CYPHER® Sirolimus-Eluting Coronary Stent Receives FDA Approval for …  -  Apr 20, 2005
Sirolimus, the active drug released for the stent, is marketed by Wyeth Pharmaceuticals, a division of Wyeth, under the name Rapamune®. ... Angioplasty.Org

Cordis' Manufacturing Facility Recognized With Shingo Prize for …  -  Feb 8, 2007
Sirolimus, the active drug released for the stent, is marketed by Wyeth Pharmaceuticals, a division of Wyeth, under the name Rapamune(R). ... Free with registration - PR Newswire - AccessMyLibrary.com

Cordis Corporation to Emphasize Commitment to Interventional …  -  Mar 20, 2007
Sirolimus, the active drug released for the stent, is marketed by Wyeth Pharmaceuticals, a division of Wyeth, under the name Rapamune(R). ... Free with registration - PR Newswire - AccessMyLibrary.com

Study Suggests CYPHER(R) Sirolimus-Eluting Coronary Stent More Cost- …  -  Jul 27, 2006
Sirolimus, the active drug released for the stent, is marketed by Wyeth Pharmaceuticals, a division of Wyeth, under the name Rapamune(R). ... Free with registration - PR Newswire - AccessMyLibrary.com

Cordis Corporation's Third-Generation Coronary Stent Approved For Use...  -  Jun 22, 2006
Sirolimus, the active drug released for the stent, is marketed by Wyeth Pharmaceuticals, a division of Wyeth, under the name Rapamune®. ... Angioplasty.Org

CYPHER STENT OUTPERFORMS TAXUS STENT IN LONG CORONARY …  -  Dec 1, 2006
Sirolimus, the active drug released for the stent, is marketed by Wyeth Pharmaceuticals, a division of Wyeth, under the name Rapamune(R). ... Free with registration - Biotech Equipment Update - AccessMyLibrary.com

Arts II Clinical Study Shows Promising Results for the Cypher(R) …  -  Mar 6, 2005
Sirolimus, the active drug released for the stent, is marketed by Wyeth Pharmaceuticals, a division of Wyeth, under the name Rapamune(R). ... Free with registration - PR Newswire Europe - AccessMyLibrary.com

Better Patient Outcomes with CYPHER(R) Sirolimus-Eluting Coronary …  -  Jun 4, 2007
Sirolimus, the active drug released for the stent, is marketed by Wyeth Pharmaceuticals, a division of Wyeth, under the name Rapamune . ... Free with registration - M2 Presswire - AccessMyLibrary.com

CYPHER® Sirolimus-Eluting Coronary Stent Receives FDA Approval for …  -  Apr 24, 2005
Sirolimus, the active drug released for the stent, is marketed by Wyeth Pharmaceuticals, a division of Wyeth, under the name Rapamune®. ... i-newswire.com

CYPHER(R) Sirolimus-Eluting Coronary Stent Outperforms Taxus Stent in...  -  Feb 2, 2006
Sirolimus, the active drug released for the stent, is marketed by Wyeth Pharmaceuticals, a division of Wyeth, under the name Rapamune(R). ... Free with registration - PR Newswire - AccessMyLibrary.com

Preliminary Long-Term Clinical Data Show Promising Results for the …  -  Nov 15, 2006
Sirolimus, the active drug released for the stent, is marketed by Wyeth Pharmaceuticals, a division of Wyeth, under the name Rapamune(R). ... Free with registration - PR Newswire - AccessMyLibrary.com

Cordis Corporation Submits Pre-Market Approval Submission For …  -  May 13, 2006
Sirolimus, the active drug released for the stent, is marketed by Wyeth Pharmaceuticals, a division of Wyeth, under the name Rapamune(R). ... Medical News Today - Medical News Today (press release)

Cordis Corporation Announces Clinical Studies And Events At TCT 2007  -  Oct 21, 2007
Sirolimus, the active drug released for the stent, is marketed by Wyeth Pharmaceuticals, a division of Wyeth, under the name Rapamune®. ... Medical News Today - Medical News Today (press release)

CORDIS PLANS MANUFACTURING FACILITY IN IRELAND.  -  Sep 1, 2006
Sirolimus, the active drug released for the stent, is marketed by Wyeth Pharmaceuticals, a division of Wyeth, under the name Rapamune(R). ... Entrepreneur

Positive CYPHER(R) Stent Data on Complex Cardiac Patients Presented …  -  Sep 6, 2005
Sirolimus, the active drug released for the stent, is marketed by Wyeth Pharmaceuticals, a division of Wyeth, under the name Rapamune(R). ... RedOrbit

Sirolimus Reduces the Risk of Cancer in Kidney Transplant Patients  -  Feb 9, 2006
In this analysis of the Rapamune Maintenance Study, 430 kidney transplant patients were randomly assigned to remain on sirolimus (SRL), cyclosporine (CsA) ... DG News

CYPHER® Sirolimus-Eluting Coronary Stent Demonstrates Sustained …  -  Sep 10, 2007
Sirolimus, the active drug released for the stent, is marketed by Wyeth Pharmaceuticals, a division of Wyeth, under the name Rapamune®. ... Medical News Today - Medical News Today (press release)

CYPHER® Sirolimus-Eluting Coronary Stent Demonstrates Sustained …  -  Apr 2, 2007
Sirolimus, the active drug released for the stent, is marketed by Wyeth Pharmaceuticals, a division of Wyeth, under the name Rapamune®. ... Medical News Today - Medical News Today (press release)

CYPHER® Sirolimus-Eluting Coronary Stent Had Similar Results To …  -  May 29, 2007
Sirolimus, the active drug released for the stent, is marketed by Wyeth Pharmaceuticals, a division of Wyeth, under the name Rapamune®. ... Medical News Today - Medical News Today (press release)

Safety and Efficacy of the Cypher(R) Sirolimus-Eluting Coronary Stent...  -  Jun 8, 2005
Rapamune is a trademark of Wyeth Pharmaceuticals. Cordis Corporation has entered into an exclusive worldwide license with Wyeth for the localized delivery ... Medical News Today - Medical News Today (press release)

Brand Names/Synonyms:
Rapamune is also known by the following brand names and/or synonymsAntibiotic Ay 22989; Rapamune; Rapamycin; Rapamycin / Sirolimus; Rapamycin, ≪ 98% by Tlc; Sirolimus; Sirolimus [Usan:Ban:Inn]

Drug Category:
Rapamune is categorized under the following by the FDA: Immunosuppressive Agents; Antifungals; Antibiotics; Anti-bacterial Agents; Unclassified Therapeutic Agents (92:00.00); ATC:L04AA10

Dosage Forms:
SOLUTION

Absorption:
Not Available

Interactions:
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Chemical IUPAC Name:
Not Available





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